To study the problem of predicting and preventing high-temperature heat damage in deep mining of mines. The heat exchange and mass exchange algorithms of the ventilation network parting wind and surrounding rock are applied, and the model of the heat exchange coefficient of the wind flow in the drenching tunnel is adopted. TF1M3D simulation platform is developed by the College of Safety Science and Engineering of Liaoning Technical University. It is a dynamic disaster simulation software that visually and dynamically reflects the disaster spread and evolution in the ventilation system during the occurrence of major disasters in mines. Based on the theory of mass-energy active wind network, TF1M3D simulation platform can solve the problems of heat and humidity exchange, heat and mass transfer numerical calculation and so on.@Combined with the engineering example of Daqiang Mine, the algorithm is incorporated into the mine network domain system, and TF1M3D is used on the MATLAB platform to simulate and solve the temperature of the wind flow of the whole mine network domain system, and predict the temperature of the 0306 working face of Daqiang Coal Mine and put forward the simulation program of refrigeration cooling. The simulation results show that the maximum temperature of the future 3106 working face of Daqiang coal mine reaches 34.6°C, and the heat damage problem is serious. In the adopted cooling program, two refrigeration units are preferred to four refrigeration units, and the effective temperature control range of the two 250 kW refrigeration units is from 25 to 305 m, while the cooling meets the temperature of the working face airflow below 30°C. The results show that the method can accurately predict the temperature of the wind flow after cooling and the location of the cooling source, which provides a basis for the scientific development of the cooling program.