The basic concept of Neuroanesthesia & Neuro Critical Care is referred to as the ABCDE of neuroanesthesia. Early Brain Injury (EBI) was formerly known as primary brain injury. In EBI there is a loss of autoregulation and loss of blood-brain barrier integrity. The presence of Cushing's triad indicates the presence of intracranial hypertension. The target of blood pressure in traumatic brain injury (TBI) is to avoid blood pressure systolic <110 mmHg, maintain cerebral perfusion pressure (CPP) 60-70 mmHg, target PaCO2 regulation is normocarbia, PaCO2 35–40 mmHg, prophylactic use of phenytoin or valproate is not recommended to prevent late post-traumatic seizures (late PTS). There is still a need to analyse decompressive craniectomy (DECRA) therapy compared with continued medical therapy for refractory intracranial pressure (ICP) elevations after TBI. General anesthesia for patients with severe TBI is preferable to total intravenous anesthesia (TIVA), the administration of fluids should consider the osmolarity of these fluids. In the new concept, in patients with elevated ICP, the volatile anesthetic concentration should be limited to 0.5 MAC. The target blood sugar is normoglycemia. Prophylactic or therapeutic hypothermia appears to have no place in the management of severe brain injury
{"title":"General anesthesia in patient with Brain Injury","authors":"Ali Anwar Alkuraishy","doi":"10.55940/medphar20224","DOIUrl":"https://doi.org/10.55940/medphar20224","url":null,"abstract":"The basic concept of Neuroanesthesia & Neuro Critical Care is referred to as the ABCDE of neuroanesthesia. Early Brain Injury (EBI) was formerly known as primary brain injury. In EBI there is a loss of autoregulation and loss of blood-brain barrier integrity. The presence of Cushing's triad indicates the presence of intracranial hypertension. The target of blood pressure in traumatic brain injury (TBI) is to avoid blood pressure systolic <110 mmHg, maintain cerebral perfusion pressure (CPP) 60-70 mmHg, target PaCO2 regulation is normocarbia, PaCO2 35–40 mmHg, prophylactic use of phenytoin or valproate is not recommended to prevent late post-traumatic seizures (late PTS). There is still a need to analyse decompressive craniectomy (DECRA) therapy compared with continued medical therapy for refractory intracranial pressure (ICP) elevations after TBI. General anesthesia for patients with severe TBI is preferable to total intravenous anesthesia (TIVA), the administration of fluids should consider the osmolarity of these fluids. In the new concept, in patients with elevated ICP, the volatile anesthetic concentration should be limited to 0.5 MAC. The target blood sugar is normoglycemia. Prophylactic or therapeutic hypothermia appears to have no place in the management of severe brain injury","PeriodicalId":7822,"journal":{"name":"Anhui Medical and Pharmaceutical Journal","volume":"185 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77345275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karam T Tawfeek, Ghufran Z. Zuhair, Hany A. Al-hussaniy, M. Naji
Background: Due to its negative effects on the unborn child and the mother as a consumer, pregnant women's intake of psychoactive substances has become a public health concern. Additionally, consuming these chemicals has been linked to several neurological development changes in children, including behavioral issues (such as attention deficit hyperactivity disorder and autism spectrum disorder), cognitive issues, and sensory and motor function changes. Objectives: To perform a thorough, comprehensive study of the neurodevelopmental problems in children linked to maternal drug use. Method: A search of the scientific literature on studies about neurodevelopmental abnormalities linked to maternal use of psychoactive medications during pregnancy and published in the previous ten years up to June 2022 was conducted from PubMed, Google Scholar, and Directory open access Journals. Results: The initial screening identified 380 articles. We excluded 50 unaccessible articles and 160 articles due to publication dates and study types; after that, 62 articles were also discarded because they were duplicates, and 68 were excluded because the information was irrelevant or systemic reviews, so we finally obtained 40 articles for full-text reading distributed as follows: 18 from PubMed, 12 from Directory Open Access Journal, and 10 from Google scholar
背景:由于对未出生的婴儿和作为消费者的母亲的负面影响，孕妇摄入精神活性物质已成为一个公共卫生问题。此外，食用这些化学物质与儿童的几种神经发育变化有关，包括行为问题(如注意力缺陷多动障碍和自闭症谱系障碍)、认知问题以及感觉和运动功能变化。目的:对与母亲吸毒有关的儿童神经发育问题进行彻底、全面的研究。方法:从PubMed、Google Scholar和Directory open access Journals检索截至2022年6月前10年发表的与孕妇妊娠期间使用精神活性药物相关的神经发育异常研究的科学文献。结果:初步筛选鉴定出380篇。由于发表日期和研究类型的原因，我们排除了50篇无法获取的文章和160篇;之后还有62篇因为重复被丢弃，68篇因为信息无关或系统评价被排除，所以我们最终获得了40篇全文阅读的文章，分布如下:18篇来自PubMed, 12篇来自Directory Open Access Journal, 10篇来自Google scholar
{"title":"Neurodevelopmental Abnormalities in Children Associated with Maternal Use of Psychoactive Medication","authors":"Karam T Tawfeek, Ghufran Z. Zuhair, Hany A. Al-hussaniy, M. Naji","doi":"10.55940/medphar202210","DOIUrl":"https://doi.org/10.55940/medphar202210","url":null,"abstract":"Background: Due to its negative effects on the unborn child and the mother as a consumer, pregnant women's intake of psychoactive substances has become a public health concern. Additionally, consuming these chemicals has been linked to several neurological development changes in children, including behavioral issues (such as attention deficit hyperactivity disorder and autism spectrum disorder), cognitive issues, and sensory and motor function changes. Objectives: To perform a thorough, comprehensive study of the neurodevelopmental problems in children linked to maternal drug use. Method: A search of the scientific literature on studies about neurodevelopmental abnormalities linked to maternal use of psychoactive medications during pregnancy and published in the previous ten years up to June 2022 was conducted from PubMed, Google Scholar, and Directory open access Journals. Results: The initial screening identified 380 articles. We excluded 50 unaccessible articles and 160 articles due to publication dates and study types; after that, 62 articles were also discarded because they were duplicates, and 68 were excluded because the information was irrelevant or systemic reviews, so we finally obtained 40 articles for full-text reading distributed as follows: 18 from PubMed, 12 from Directory Open Access Journal, and 10 from Google scholar","PeriodicalId":7822,"journal":{"name":"Anhui Medical and Pharmaceutical Journal","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77950683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-01-01DOI: 10.1016/b978-1-4160-3969-3.00254-7
Xu Fei-fan
{"title":"Cardiopulmonary cerebral resuscitation","authors":"Xu Fei-fan","doi":"10.1016/b978-1-4160-3969-3.00254-7","DOIUrl":"https://doi.org/10.1016/b978-1-4160-3969-3.00254-7","url":null,"abstract":"","PeriodicalId":7822,"journal":{"name":"Anhui Medical and Pharmaceutical Journal","volume":"175 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84999467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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