Pub Date : 2026-01-01Epub Date: 2025-07-23DOI: 10.1097/PHM.0000000000002803
Donald Kasitinon, Reed Williams, Veena Peraka, Levent Özçakar, Nitin B Jain
Purpose: The aim of the study was to review the current literature on the accuracy and efficacy of ultrasound- and landmark-guided intra-articular knee injections.
Methods: A systematic review was performed following the Cochrane process from April 2023 to August 2023 utilizing PubMed, Embase, Web of Science, and Scopus. Branched logic was used to include articles containing terms regarding the knee AND ultrasound AND injections. Two authors screened studies for eligibility, and any disagreement was resolved through discussion with a third reviewer. Risk-of-bias assessments were performed.
Results: A total of 13 studies were included in the review. Cumulative accuracies amounted to 95.4% (356/373) versus 82.0% (268/327) for ultrasound-guided and landmark-guided intra-articular knee injections/aspirations, respectively. All but one study looking at efficacy showed significantly improved outcomes in the ultrasound-guided injection/aspiration groups.
Conclusions: This systematic review provides data to support that ultrasound-guided intra-articular knee injections/aspirations are more accurate and efficacious than landmark-guided intra-articular knee injections/aspirations.
Level of evidence: Level I - systematic review.
目的:回顾超声(US)和路标(LM)引导下膝关节关节内注射的准确性和有效性。方法:利用PubMed、Embase、Web of Science和Scopus,对2023年4月至2023年8月的Cochrane过程进行系统评价。分支逻辑被用来包括包含关于膝盖、超声和注射的术语的文章。两位作者筛选研究的合格性,任何分歧都通过与第三位审稿人讨论来解决。进行偏倚风险评估。结果:本综述共纳入13项研究。在us引导和lm引导下,膝关节关节内注射/穿刺的累计准确率分别为95.4%(356/373)和82.0%(268/327)。除一项研究外,其他研究均显示在us引导下注射/抽吸组的疗效显著改善。结论:本系统综述提供的数据支持us引导的膝关节关节内注射/入路比lm引导的膝关节关节内注射/入路更准确和有效。证据等级:一级——系统评价。
{"title":"Accuracy and Efficacy of Intra-articular Knee Injections/Aspirations Under Ultrasound Versus Landmark Guidance: A Systematic Review.","authors":"Donald Kasitinon, Reed Williams, Veena Peraka, Levent Özçakar, Nitin B Jain","doi":"10.1097/PHM.0000000000002803","DOIUrl":"10.1097/PHM.0000000000002803","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the study was to review the current literature on the accuracy and efficacy of ultrasound- and landmark-guided intra-articular knee injections.</p><p><strong>Methods: </strong>A systematic review was performed following the Cochrane process from April 2023 to August 2023 utilizing PubMed, Embase, Web of Science, and Scopus. Branched logic was used to include articles containing terms regarding the knee AND ultrasound AND injections. Two authors screened studies for eligibility, and any disagreement was resolved through discussion with a third reviewer. Risk-of-bias assessments were performed.</p><p><strong>Results: </strong>A total of 13 studies were included in the review. Cumulative accuracies amounted to 95.4% (356/373) versus 82.0% (268/327) for ultrasound-guided and landmark-guided intra-articular knee injections/aspirations, respectively. All but one study looking at efficacy showed significantly improved outcomes in the ultrasound-guided injection/aspiration groups.</p><p><strong>Conclusions: </strong>This systematic review provides data to support that ultrasound-guided intra-articular knee injections/aspirations are more accurate and efficacious than landmark-guided intra-articular knee injections/aspirations.</p><p><strong>Level of evidence: </strong>Level I - systematic review.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"1-11"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Stroke is a major cause of disability, impacting mobility worldwide. Overground robotic-assisted gait training uses wearable exoskeletons to improve walking. This systematic review and meta-analysis assess its effectiveness versus conventional gait training in enhancing gait velocity and balance in poststroke patients.
Design: Our search was conducted in the Pubmed, Cochrane, ScienceDirect, Scopus, and PEDro electronic databases for English journal articles about human randomized controlled trials of the last two decades, investigating overground robotic-assisted gait training effects on gait parameters of poststroke patients compared with conventional gait training.
Results: A comprehensive literature search identified seven randomized controlled trials with a total of 288 participants. Meta-analysis results indicated that overground robotic-assisted gait training significantly improved after intervention gait velocity (summary mean difference: 0.09 m/sec, 95% confidence interval 0.02-0.17), while other gait parameters, such as stride length and cadence, showed no statistically significant differences. The intervention was well-tolerated, with no major adverse events reported.
Conclusions: Despite the positive impact on gait speed, challenges remain, including high device costs and the need for further research to optimize training parameters. These findings support the potential of overground robotic-assisted gait training as an effective tool for gait rehabilitation in stroke survivors, highlighting the need for larger studies with long-term follow-up to refine its clinical application.
{"title":"Assessment of the Robotic Devices for Overground Gait Training in Poststroke Patient: A Systematic Review and Meta-analysis.","authors":"Avraam Ploumis, Panagiota Gkatziani, Paraskevi Tsingeli, Georgios Ntritsos, Dimitrios Dimopoulos, Alexandros Athanasiou, Athanasios Kefalas, Dimitrios N Varvarousis","doi":"10.1097/PHM.0000000000002793","DOIUrl":"10.1097/PHM.0000000000002793","url":null,"abstract":"<p><strong>Objective: </strong>Stroke is a major cause of disability, impacting mobility worldwide. Overground robotic-assisted gait training uses wearable exoskeletons to improve walking. This systematic review and meta-analysis assess its effectiveness versus conventional gait training in enhancing gait velocity and balance in poststroke patients.</p><p><strong>Design: </strong>Our search was conducted in the Pubmed, Cochrane, ScienceDirect, Scopus, and PEDro electronic databases for English journal articles about human randomized controlled trials of the last two decades, investigating overground robotic-assisted gait training effects on gait parameters of poststroke patients compared with conventional gait training.</p><p><strong>Results: </strong>A comprehensive literature search identified seven randomized controlled trials with a total of 288 participants. Meta-analysis results indicated that overground robotic-assisted gait training significantly improved after intervention gait velocity (summary mean difference: 0.09 m/sec, 95% confidence interval 0.02-0.17), while other gait parameters, such as stride length and cadence, showed no statistically significant differences. The intervention was well-tolerated, with no major adverse events reported.</p><p><strong>Conclusions: </strong>Despite the positive impact on gait speed, challenges remain, including high device costs and the need for further research to optimize training parameters. These findings support the potential of overground robotic-assisted gait training as an effective tool for gait rehabilitation in stroke survivors, highlighting the need for larger studies with long-term follow-up to refine its clinical application.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"12-19"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-11-19DOI: 10.1097/PHM.0000000000002802
Michelle LA Nelson, Jing Shi, M Patrice Lindsay, Nancy M Salbach, Jennifer K Yao, Debbie Timpson, Benjamin R Ritsma, Louis-Pierre Auger, Jenna Beaumont, Rebecca Bowes, Imane Samah Chibane, Sarah J Courtice, Rhina Delgado, Melanie Dunlop, Norine Foley, Kimia Ghavami, Teresa Guolla, Deborah Kean, Sandra MacFayden, Jasmine Masse, Phyllis G Paterson, Elyse Shumway, Ada Tang, Alda Tee, Clinton Y H Tsang, Stacey Turnbull, Dylan Blacquiere, Katie White, Chelsy Martin, Rebecca Lund, Elizabeth L Inness, Brodie Sakakibara, Gustavo Saposnik, Ruth Barclay, Diana Bastasi, Mark I Boulos, Joy Boyce, Geneviève Claveau, Heather L Flowers, Urvashy Gopaul, Esther S Kim, Alto Lo, Alison M McDonald, Amanda McIntyre, Colleen O'Connor, Kara K Patterson, Tricia Shoniker, Theodore Wein, Janice Wright, Brenda Yeates, Jeanne Yiu, Colleen O'Connell, Sarvenaz Mehrabi, Anita Mountain
Abstract: The Canadian Stroke Best Practice Recommendations 7 th edition update of the Rehabilitation, Recovery and Community Participation module is presented in three parts. This publication, Part One of the series, reflects the growing and changing body of research evidence available to guide planning, ongoing screening and assessment, management, education, and support of individuals with stroke, their families, and caregivers. This module provides guidance for the planning and delivery of coordinated and seamless systems of care from acute stroke onset to return to community settings by an interdisciplinary team of healthcare providers with expertise in stroke. These recommendations were developed with active involvement of people with lived experience of stroke at all phases. These recommendations are intended to support the progress achieved during the initial recovery stages and enable individuals with stroke to resume life roles and leisure activities as best as possible, to achieve optimal recovery goals. Evidence for effective rehabilitation therapies and support for individuals with stroke and their families continues to emerge and gaps in knowledge should drive future research.
{"title":"Canadian Stroke Best Practice Recommendations: Rehabilitation, Recovery and Community Participation Following Stroke. Part One: Stroke Rehabilitation Planning for Optimal Care Delivery, 7th Edition Update 2025.","authors":"Michelle LA Nelson, Jing Shi, M Patrice Lindsay, Nancy M Salbach, Jennifer K Yao, Debbie Timpson, Benjamin R Ritsma, Louis-Pierre Auger, Jenna Beaumont, Rebecca Bowes, Imane Samah Chibane, Sarah J Courtice, Rhina Delgado, Melanie Dunlop, Norine Foley, Kimia Ghavami, Teresa Guolla, Deborah Kean, Sandra MacFayden, Jasmine Masse, Phyllis G Paterson, Elyse Shumway, Ada Tang, Alda Tee, Clinton Y H Tsang, Stacey Turnbull, Dylan Blacquiere, Katie White, Chelsy Martin, Rebecca Lund, Elizabeth L Inness, Brodie Sakakibara, Gustavo Saposnik, Ruth Barclay, Diana Bastasi, Mark I Boulos, Joy Boyce, Geneviève Claveau, Heather L Flowers, Urvashy Gopaul, Esther S Kim, Alto Lo, Alison M McDonald, Amanda McIntyre, Colleen O'Connor, Kara K Patterson, Tricia Shoniker, Theodore Wein, Janice Wright, Brenda Yeates, Jeanne Yiu, Colleen O'Connell, Sarvenaz Mehrabi, Anita Mountain","doi":"10.1097/PHM.0000000000002802","DOIUrl":"10.1097/PHM.0000000000002802","url":null,"abstract":"<p><strong>Abstract: </strong>The Canadian Stroke Best Practice Recommendations 7 th edition update of the Rehabilitation, Recovery and Community Participation module is presented in three parts. This publication, Part One of the series, reflects the growing and changing body of research evidence available to guide planning, ongoing screening and assessment, management, education, and support of individuals with stroke, their families, and caregivers. This module provides guidance for the planning and delivery of coordinated and seamless systems of care from acute stroke onset to return to community settings by an interdisciplinary team of healthcare providers with expertise in stroke. These recommendations were developed with active involvement of people with lived experience of stroke at all phases. These recommendations are intended to support the progress achieved during the initial recovery stages and enable individuals with stroke to resume life roles and leisure activities as best as possible, to achieve optimal recovery goals. Evidence for effective rehabilitation therapies and support for individuals with stroke and their families continues to emerge and gaps in knowledge should drive future research.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"59-75"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145547743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-08-18DOI: 10.1097/PHM.0000000000002843
Dylan B Combs, Joseph Ruiz, George Ross Malik
{"title":"Sudden-Onset Neck Pain in an Otherwise Healthy Young Male.","authors":"Dylan B Combs, Joseph Ruiz, George Ross Malik","doi":"10.1097/PHM.0000000000002843","DOIUrl":"10.1097/PHM.0000000000002843","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"e8-e10"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-08-11DOI: 10.1097/PHM.0000000000002792
Xinwei Zhu, Le Jiao, Qingmei Chen, Zhexuan Kuang, Jing Shang
Objective: This study compared the effects of continuous theta burst stimulation and low-frequency repetitive transcranial magnetic stimulation on cortical activity modulation and upper limb motor recovery in subacute stroke patients.
Design: A total of 105 subacute stroke patients with unilateral upper limb impairment were randomly divided into the following three groups: continuous theta burst stimulation, low-frequency repetitive transcranial magnetic stimulation, and sham. Main outcomes included upper extremity Fugl-Meyer score and modified Barthel Index scores at baseline, 4 wks (posttreatment), and 12 wks (follow-up). Secondary outcomes evaluated cortical activation via functional near-infrared spectroscopy.
Results: Among 103 recruited participants, 98 completed follow-up. Both continuous theta burst stimulation and low-frequency repetitive transcranial magnetic stimulation groups showed significantly greater upper extremity Fugl-Meyer improvement than the sham group at 4 and 12 wks ( P < 0.05), while modified Barthel Index scores did not differ significantly. Functional near-infrared spectroscopy revealed that active treatments suppressed contralesional primary motor cortex activation, with continuous theta burst stimulation additionally inhibiting premotor and supplementary motor areas.
Conclusions: Continuous theta burst stimulation and low-frequency repetitive transcranial magnetic stimulation effectively enhanced upper limb motor motricity in stroke patients compared to sham stimulation, suggesting their potential as noninvasive neuromodulatory therapies for poststroke rehabilitation.
{"title":"Effects of Transcranial Magnetic Stimulation on Patients of Poststroke Upper Extremity Motor Impairment: A Randomized Controlled Trial.","authors":"Xinwei Zhu, Le Jiao, Qingmei Chen, Zhexuan Kuang, Jing Shang","doi":"10.1097/PHM.0000000000002792","DOIUrl":"10.1097/PHM.0000000000002792","url":null,"abstract":"<p><strong>Objective: </strong>This study compared the effects of continuous theta burst stimulation and low-frequency repetitive transcranial magnetic stimulation on cortical activity modulation and upper limb motor recovery in subacute stroke patients.</p><p><strong>Design: </strong>A total of 105 subacute stroke patients with unilateral upper limb impairment were randomly divided into the following three groups: continuous theta burst stimulation, low-frequency repetitive transcranial magnetic stimulation, and sham. Main outcomes included upper extremity Fugl-Meyer score and modified Barthel Index scores at baseline, 4 wks (posttreatment), and 12 wks (follow-up). Secondary outcomes evaluated cortical activation via functional near-infrared spectroscopy.</p><p><strong>Results: </strong>Among 103 recruited participants, 98 completed follow-up. Both continuous theta burst stimulation and low-frequency repetitive transcranial magnetic stimulation groups showed significantly greater upper extremity Fugl-Meyer improvement than the sham group at 4 and 12 wks ( P < 0.05), while modified Barthel Index scores did not differ significantly. Functional near-infrared spectroscopy revealed that active treatments suppressed contralesional primary motor cortex activation, with continuous theta burst stimulation additionally inhibiting premotor and supplementary motor areas.</p><p><strong>Conclusions: </strong>Continuous theta burst stimulation and low-frequency repetitive transcranial magnetic stimulation effectively enhanced upper limb motor motricity in stroke patients compared to sham stimulation, suggesting their potential as noninvasive neuromodulatory therapies for poststroke rehabilitation.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"20-27"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-09-01DOI: 10.1097/PHM.0000000000002787
David J Rothman, Scott D McDonald, William C Walker, George Feldman
{"title":"Olfactory Changes After Military Deployment Are Associated With Emotional Distress but Not With Mild Traumatic Brain Injury History.","authors":"David J Rothman, Scott D McDonald, William C Walker, George Feldman","doi":"10.1097/PHM.0000000000002787","DOIUrl":"10.1097/PHM.0000000000002787","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"87-88"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-07-23DOI: 10.1097/PHM.0000000000002801
Jana Dengler, Maytal Perlman, Michelle Jennett, Melanie Barwick, Kristin E Musselman, Anita Kaiser, Edyta Marcon, Sander L Hitzig
Objective: Nerve and tendon transfer surgery has restored upper extremity function in cervical spinal cord injury but is not universally accessible to all eligible individuals. The purpose of this exploratory qualitative study was to understand the healthcare provider factors that are associated with access to nerve transfer surgery for people with spinal cord injury.
Design: Semistructured interviews explored healthcare provider knowledge and practices regarding nerve and tendon transfer surgery to improve upper extremity function in cervical spinal cord injury. An inductive, iterative, constant comparative process involving descriptive and interpretive data analyses was used to identify themes, guided by the Consolidated Framework for Implementation Research.
Results: Interviews were conducted with healthcare providers ( n = 10 upper extremity surgeons, n = 10 spinal cord injury physiatrists/hospitalists, n = 6 occupational therapists, n = 6 physical therapists). The following nine themes were identified as barriers to accessing care: (1) lack of awareness; (2) lack of sufficient knowledge; (3) lack of buy-in as a priority; (4) lack of collaboration; (5) misperceptions; (6) lack of resources; (7) lack of evidence; (8) lack of ownership among rehabilitation specialists; and (9) hesitancy.
Conclusions: This study identified barriers limiting equitable access to nerve transfer surgery. These barriers highlight the need for a multimodal multidisciplinary approach to address individual-, provider-, and system-level barriers.
{"title":"Healthcare Provider Factors Affecting Access to Nerve Transfer Surgery to Improve Upper Extremity Function in Individuals With Cervical Spinal Cord Injury.","authors":"Jana Dengler, Maytal Perlman, Michelle Jennett, Melanie Barwick, Kristin E Musselman, Anita Kaiser, Edyta Marcon, Sander L Hitzig","doi":"10.1097/PHM.0000000000002801","DOIUrl":"10.1097/PHM.0000000000002801","url":null,"abstract":"<p><strong>Objective: </strong>Nerve and tendon transfer surgery has restored upper extremity function in cervical spinal cord injury but is not universally accessible to all eligible individuals. The purpose of this exploratory qualitative study was to understand the healthcare provider factors that are associated with access to nerve transfer surgery for people with spinal cord injury.</p><p><strong>Design: </strong>Semistructured interviews explored healthcare provider knowledge and practices regarding nerve and tendon transfer surgery to improve upper extremity function in cervical spinal cord injury. An inductive, iterative, constant comparative process involving descriptive and interpretive data analyses was used to identify themes, guided by the Consolidated Framework for Implementation Research.</p><p><strong>Results: </strong>Interviews were conducted with healthcare providers ( n = 10 upper extremity surgeons, n = 10 spinal cord injury physiatrists/hospitalists, n = 6 occupational therapists, n = 6 physical therapists). The following nine themes were identified as barriers to accessing care: (1) lack of awareness; (2) lack of sufficient knowledge; (3) lack of buy-in as a priority; (4) lack of collaboration; (5) misperceptions; (6) lack of resources; (7) lack of evidence; (8) lack of ownership among rehabilitation specialists; and (9) hesitancy.</p><p><strong>Conclusions: </strong>This study identified barriers limiting equitable access to nerve transfer surgery. These barriers highlight the need for a multimodal multidisciplinary approach to address individual-, provider-, and system-level barriers.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"33-40"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-07-29DOI: 10.1097/PHM.0000000000002800
Eric Lukas Voorn, Sander Oorschot, Nicolette Janine Wierdsma, Maarten René Soeters, Fieke Sophia Koopman, Annerieke Ceciel van Groenestijn
Objective: The metabolic syndrome is a growing health issue. This study evaluated the prevalence of metabolic syndrome and individual metabolic syndrome risk factors, in people with different neuromuscular diseases.
Design: We used baseline data of a randomized controlled trial on the efficacy of a physical activity program in neuromuscular diseases. Metabolic syndrome was defined as the presence of at least three out of five risk factors of the revised National Cholesterol Education Program Adult Treatment Panel III.
Results: The 84 participants (50 female, median age = 63 yrs, interquartile range = 48, 68 yrs) were diagnosed with post-polio syndrome ( n = 22), Charcot-Marie-Tooth disease ( n = 37) or other neuromuscular diseases ( n = 25). Metabolic syndrome was present in 18 participants (21%). The most common risk factors were hypertension (56%), central obesity (49%), and increased fasting blood glucose (33%). Logistic regression results showed that adjusted for age and muscle strength as confounders, participants with Charcot-Marie-Tooth disease (Exp(B) = 0.107, 95% confidence interval: 0.019-0.609) and other neuromuscular diseases (Exp(B) = 0.039, 95% confidence interval: 0.004-0.390) had significantly lower odds of metabolic syndrome compared with post-polio syndrome.
Conclusions: The metabolic syndrome prevalence that we found is comparable to the general Dutch population. However, a focus on the prevention of metabolic syndrome in neuromuscular rehabilitation is warranted, as certain neuromuscular diseases subgroups may be at increased risk of developing metabolic syndrome.
{"title":"Metabolic Syndrome in Ambulatory People With Post-Polio Syndrome, Charcot-Marie-Tooth Disease, and Other Neuromuscular Diseases.","authors":"Eric Lukas Voorn, Sander Oorschot, Nicolette Janine Wierdsma, Maarten René Soeters, Fieke Sophia Koopman, Annerieke Ceciel van Groenestijn","doi":"10.1097/PHM.0000000000002800","DOIUrl":"10.1097/PHM.0000000000002800","url":null,"abstract":"<p><strong>Objective: </strong>The metabolic syndrome is a growing health issue. This study evaluated the prevalence of metabolic syndrome and individual metabolic syndrome risk factors, in people with different neuromuscular diseases.</p><p><strong>Design: </strong>We used baseline data of a randomized controlled trial on the efficacy of a physical activity program in neuromuscular diseases. Metabolic syndrome was defined as the presence of at least three out of five risk factors of the revised National Cholesterol Education Program Adult Treatment Panel III.</p><p><strong>Results: </strong>The 84 participants (50 female, median age = 63 yrs, interquartile range = 48, 68 yrs) were diagnosed with post-polio syndrome ( n = 22), Charcot-Marie-Tooth disease ( n = 37) or other neuromuscular diseases ( n = 25). Metabolic syndrome was present in 18 participants (21%). The most common risk factors were hypertension (56%), central obesity (49%), and increased fasting blood glucose (33%). Logistic regression results showed that adjusted for age and muscle strength as confounders, participants with Charcot-Marie-Tooth disease (Exp(B) = 0.107, 95% confidence interval: 0.019-0.609) and other neuromuscular diseases (Exp(B) = 0.039, 95% confidence interval: 0.004-0.390) had significantly lower odds of metabolic syndrome compared with post-polio syndrome.</p><p><strong>Conclusions: </strong>The metabolic syndrome prevalence that we found is comparable to the general Dutch population. However, a focus on the prevention of metabolic syndrome in neuromuscular rehabilitation is warranted, as certain neuromuscular diseases subgroups may be at increased risk of developing metabolic syndrome.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"41-46"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01Epub Date: 2025-06-13DOI: 10.1097/PHM.0000000000002795
Michael B Furman, Gene Tekmyster, Lelia Gilhool, Jesse S Bernstein, Ajay R Kurup, Christopher T Bednarek, Holden M Caplan, Byron Schneider
Background: Facet joint interventions are commonly performed procedures in patients with neck and back pain, including patients managed with anticoagulant/antiplatelet medications. Temporary cessation of anticoagulant/antiplatelet medications may increase the risk of thromboembolic complications, which may be unnecessary.
Objective: The aim of the study was to determine the risk of clinically relevant hemorrhagic complications in patients undergoing facet interventions.
Methods: Consecutive patients from September 19, 2009, to June 16, 2017, who were on anticoagulant/antiplatelet medication medications and scheduled for an any facet intervention in the cervical, thoracic, and lumbosacral spine were retrospectively audited for bleeding complications for a minimum of 90 days after procedure.
Results: Five hundred eighty-two procedures targeting the cervical, thoracic, or lumbosacral facet joints were performed on patients on anticoagulant or antiplatelet medications. One hundred twenty-eight patients ceased their anticoagulant/antiplatelet medications before the procedure and 454 maintained anticoagulant/antiplatelet medications. No clinically relevant epidural hematomas were noted in the patient cohort (0/582, 0%, 95% confidence interval = 0.0%-0.6%).
Discussion/conclusions: The risk of clinically relevant bleeding complications including epidural hematoma in properly performed facet interventions is low. This information is crucial in being able to quantitatively determine the risk of ceasing or maintaining anticoagulant/antiplatelet medications before cervical thoracic and lumbar facet interventions.
背景:小关节干预通常用于颈背痛患者,包括使用抗凝血/抗血小板药物(ACAP)治疗的患者。暂时停止ACAP药物可能会增加血栓栓塞并发症的风险,这可能是不必要的。目的:确定接受关节突介入治疗的患者发生临床相关出血并发症的风险。方法:2009年9月19日至2017年6月16日,连续接受ACAP药物治疗并计划在颈椎、胸椎和腰骶椎进行任何关节面介入治疗的患者,回顾性审查术后至少90天的出血并发症。结果:582例针对使用AC或AP药物的患者进行了针对颈椎、胸椎或腰骶关节突关节的手术。128例患者在手术前停止ACAP治疗,454例患者继续使用ACAP治疗。患者队列中未发现临床相关的硬膜外血肿(EH) (0/ 582,0%, 95% CI 0-0.6%)。讨论/结论:临床相关出血并发症(包括硬膜外血肿)在适当的关节突干预中发生的风险很低。这一信息对于定量确定在颈椎、胸椎和腰椎关节突干预前停止或维持ACAP药物治疗的风险至关重要。
{"title":"Epidural Hematoma Risks Associated With Ceasing Versus Maintaining Anticoagulant and/or Antiplatelet Medications for Spine Facet Interventions.","authors":"Michael B Furman, Gene Tekmyster, Lelia Gilhool, Jesse S Bernstein, Ajay R Kurup, Christopher T Bednarek, Holden M Caplan, Byron Schneider","doi":"10.1097/PHM.0000000000002795","DOIUrl":"10.1097/PHM.0000000000002795","url":null,"abstract":"<p><strong>Background: </strong>Facet joint interventions are commonly performed procedures in patients with neck and back pain, including patients managed with anticoagulant/antiplatelet medications. Temporary cessation of anticoagulant/antiplatelet medications may increase the risk of thromboembolic complications, which may be unnecessary.</p><p><strong>Objective: </strong>The aim of the study was to determine the risk of clinically relevant hemorrhagic complications in patients undergoing facet interventions.</p><p><strong>Methods: </strong>Consecutive patients from September 19, 2009, to June 16, 2017, who were on anticoagulant/antiplatelet medication medications and scheduled for an any facet intervention in the cervical, thoracic, and lumbosacral spine were retrospectively audited for bleeding complications for a minimum of 90 days after procedure.</p><p><strong>Results: </strong>Five hundred eighty-two procedures targeting the cervical, thoracic, or lumbosacral facet joints were performed on patients on anticoagulant or antiplatelet medications. One hundred twenty-eight patients ceased their anticoagulant/antiplatelet medications before the procedure and 454 maintained anticoagulant/antiplatelet medications. No clinically relevant epidural hematomas were noted in the patient cohort (0/582, 0%, 95% confidence interval = 0.0%-0.6%).</p><p><strong>Discussion/conclusions: </strong>The risk of clinically relevant bleeding complications including epidural hematoma in properly performed facet interventions is low. This information is crucial in being able to quantitatively determine the risk of ceasing or maintaining anticoagulant/antiplatelet medications before cervical thoracic and lumbar facet interventions.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"28-32"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of the study was to evaluate the predictive accuracy of the Global Fatty Degeneration Index for retear risk after rotator cuff repair.
Design: A single-cohort longitudinal study using historical data was conducted. Data on patient demographics, clinical comorbidities (e.g., diabetes mellitus), and preoperative rotator cuff fatty infiltration, quantified by the Global Fatty Degeneration Index from magnetic resonance imaging, were analyzed in patients undergoing primary rotator cuff repair between January 2014 and December 2018.
Results: Among 334 patients, 42 (12.6%) experienced retears. No significant differences were found in age, sex, or body mass index, except for diabetes mellitus, which was more prevalent in the retear group ( P = 0.012). The mean Global Fatty Degeneration Index was significantly higher in the retear group (2.3 ± 0.7 vs. 1.3 ± 0.5, P < 0.001). Receiver operating characteristic analysis demonstrated strong predictive capability (area under the curve = 0.866). A Global Fatty Degeneration Index of ≥1.875 yielded a sensitivity of 77.6% and specificity of 89.4%. Logistic regression showed an odds ratio of 18.059 for retears at Global Fatty Degeneration Index ≥1.875 ( P < 0.001), with significant associations for subscapularis (OR = 4.530, P = 0.019) and infraspinatus (odds ratio = 2.928, P = 0.043) Global Fatty Degeneration Index ≥3.
Conclusions: The Global Fatty Degeneration Index is a reliable quantitative predictor of retear after rotator cuff repair, with clinical relevance for risk assessment.
目的:评价全球脂肪变性指数(GFDI)对肩袖修复(RCR)术后再撕裂风险的预测准确性。设计:采用历史数据进行单队列纵向研究。通过磁共振成像的全球脂肪变性指数(GFDI)量化患者人口统计学、临床合并症(如糖尿病)和术前肩袖脂肪浸润的数据,分析了2014年1月至2018年12月接受原发性RCR的患者。结果:334例患者中,42例(12.6%)出现复发。除糖尿病外,年龄、性别和BMI均无显著差异(P = 0.012)。retear组GFDI均值显著高于前者(2.3±0.7 vs. 1.3±0.5,P < 0.001)。ROC分析显示较强的预测能力(AUC = 0.866)。GFDI≥1.875的敏感性为77.6%,特异性为89.4%。Logistic回归结果显示,GFDI≥1.875时的优势比(OR)为18.059 (P < 0.001),肩胛下肌(OR = 4.530, P = 0.019)和冈下肌(OR = 2.928, P = 0.043) GFDI≥3时的优势比显著相关。结论:GFDI是RCR后retear的可靠定量预测因子,对风险评估具有临床意义。
{"title":"Assessing the Accuracy of Rotator Cuff Muscular Fat Infiltration Status in Predicting Symptomatic Retear After Repair Surgery.","authors":"Mei-Sean Loh, Shih-Wei Huang, Chih-Kuang Chen, Lien-Chieh Lin, Che-Li Lin, Yu-Hao Lee","doi":"10.1097/PHM.0000000000002870","DOIUrl":"10.1097/PHM.0000000000002870","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to evaluate the predictive accuracy of the Global Fatty Degeneration Index for retear risk after rotator cuff repair.</p><p><strong>Design: </strong>A single-cohort longitudinal study using historical data was conducted. Data on patient demographics, clinical comorbidities (e.g., diabetes mellitus), and preoperative rotator cuff fatty infiltration, quantified by the Global Fatty Degeneration Index from magnetic resonance imaging, were analyzed in patients undergoing primary rotator cuff repair between January 2014 and December 2018.</p><p><strong>Results: </strong>Among 334 patients, 42 (12.6%) experienced retears. No significant differences were found in age, sex, or body mass index, except for diabetes mellitus, which was more prevalent in the retear group ( P = 0.012). The mean Global Fatty Degeneration Index was significantly higher in the retear group (2.3 ± 0.7 vs. 1.3 ± 0.5, P < 0.001). Receiver operating characteristic analysis demonstrated strong predictive capability (area under the curve = 0.866). A Global Fatty Degeneration Index of ≥1.875 yielded a sensitivity of 77.6% and specificity of 89.4%. Logistic regression showed an odds ratio of 18.059 for retears at Global Fatty Degeneration Index ≥1.875 ( P < 0.001), with significant associations for subscapularis (OR = 4.530, P = 0.019) and infraspinatus (odds ratio = 2.928, P = 0.043) Global Fatty Degeneration Index ≥3.</p><p><strong>Conclusions: </strong>The Global Fatty Degeneration Index is a reliable quantitative predictor of retear after rotator cuff repair, with clinical relevance for risk assessment.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"51-58"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145501717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}