Pub Date : 1969-01-01DOI: 10.1177/030098586900600403
D F Johnson, D G Brown
A lesion designated as an intradural spinal lipoma was characterized by evident origin within the pia mater and by composition of well-differentiated adipose tissue with some fibrous stroma. Increased pial thickness and fibrous proliferation from the pia mater into the underlying neural tissue accompanied the neoplasm. No attachment of this growth to either the arachnoid or the dura mater could be discerned at any site examined. Since arachnoidal cells were not observed as components, the neoplastic tissue was not considered to be a variant of the meningioma.
{"title":"Intradural spinal lipoma in an experimental swine.","authors":"D F Johnson, D G Brown","doi":"10.1177/030098586900600403","DOIUrl":"https://doi.org/10.1177/030098586900600403","url":null,"abstract":"A lesion designated as an intradural spinal lipoma was characterized by evident origin within the pia mater and by composition of well-differentiated adipose tissue with some fibrous stroma. Increased pial thickness and fibrous proliferation from the pia mater into the underlying neural tissue accompanied the neoplasm. No attachment of this growth to either the arachnoid or the dura mater could be discerned at any site examined. Since arachnoidal cells were not observed as components, the neoplastic tissue was not considered to be a variant of the meningioma.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 4","pages":"342-7"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600403","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15294266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600605
L Z Saunders, L W Geib, C N Barron
An intraocular neoplasm is reported from a 5-1/2-month-old dog, which had had clinical signs of ophthalmic disease for about 3 months prior to exenteration. The vitreous chamber was filled with a subretinal neoplastic mass, which consisted histologically of a mixture of glial cells, nerve cells, nerve fibers, and cells resembling ependyma with some cartilage, bone, and bone marrow. The tumor was diagnosed as a ganglioglioma, a neoplasm which occurs occasionally in human brains and very rarely in human eyes. This is the first report of such a tumor in an animal other than man and the 5th report of it in an intraocular location. As in the human cases, the neoplasm was apparently present at birth or developed shortly thereafter.
{"title":"Intraocular ganglioglioma in a dog.","authors":"L Z Saunders, L W Geib, C N Barron","doi":"10.1177/030098586900600605","DOIUrl":"https://doi.org/10.1177/030098586900600605","url":null,"abstract":"An intraocular neoplasm is reported from a 5-1/2-month-old dog, which had had clinical signs of ophthalmic disease for about 3 months prior to exenteration. The vitreous chamber was filled with a subretinal neoplastic mass, which consisted histologically of a mixture of glial cells, nerve cells, nerve fibers, and cells resembling ependyma with some cartilage, bone, and bone marrow. The tumor was diagnosed as a ganglioglioma, a neoplasm which occurs occasionally in human brains and very rarely in human eyes. This is the first report of such a tumor in an animal other than man and the 5th report of it in an intraocular location. As in the human cases, the neoplasm was apparently present at birth or developed shortly thereafter.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 6","pages":"525-33"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600605","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16475325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600510
R D Jolly, M R Alley
Three calves with a history of neurological disturbances suggesting cerebellar dysfunction were submitted for necropsy. In each case a tumour was found attached to, and continuous with, the anterior cerebellum. Histologically all were medulloblastomas.
{"title":"Medulloblastoma in calves. A report of three cases.","authors":"R D Jolly, M R Alley","doi":"10.1177/030098586900600510","DOIUrl":"https://doi.org/10.1177/030098586900600510","url":null,"abstract":"Three calves with a history of neurological disturbances suggesting cerebellar dysfunction were submitted for necropsy. In each case a tumour was found attached to, and continuous with, the anterior cerebellum. Histologically all were medulloblastomas.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 5","pages":"463-8"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600510","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16476049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600302
C W Nichols, M Yanoff
The unique occurrence of a solid corneal dermoid in a laboratory rat is described. No other report of such a tumor could be found in the literature.
{"title":"Dermoid of a rat cornea.","authors":"C W Nichols, M Yanoff","doi":"10.1177/030098586900600302","DOIUrl":"https://doi.org/10.1177/030098586900600302","url":null,"abstract":"The unique occurrence of a solid corneal dermoid in a laboratory rat is described. No other report of such a tumor could be found in the literature.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 3","pages":"214-6"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600302","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16889766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600204
D F Brobst, G C Dulac
Fibromatous tumors were induced in the meninges of calves by inoculating the meninges with a suspension of bovine cutaneous papillomas or by implanting bovine cutaneous papillomas into the brain. Meningeal tumors were observed to occur as early as 20 days after inoculation. Meningeal tumors from calves killed 90 and 145 days after inoculation extended into the brain along the course of blood vessels. Metastasis, however, was not observed. Evidence that the induced meningeal tumors contained viral antigen was lacking.
{"title":"Meningeal tumors induced in calves with the bovine cutaneous papilloma virus.","authors":"D F Brobst, G C Dulac","doi":"10.1177/030098586900600204","DOIUrl":"https://doi.org/10.1177/030098586900600204","url":null,"abstract":"Fibromatous tumors were induced in the meninges of calves by inoculating the meninges with a suspension of bovine cutaneous papillomas or by implanting bovine cutaneous papillomas into the brain. Meningeal tumors were observed to occur as early as 20 days after inoculation. Meningeal tumors from calves killed 90 and 145 days after inoculation extended into the brain along the course of blood vessels. Metastasis, however, was not observed. Evidence that the induced meningeal tumors contained viral antigen was lacking.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 2","pages":"135-45"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15416933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600607
E Teuscher, E Vásconez López
Zusammenfassung Es werden drei Fälle von Aneurysma dissecans beim Kalb beschrieben. Zwei Tiere starben an Haemopericardium, ein Tier an Haemothorax. Bei einem Tier wurden am Vorabend Kolikerscheinungen beobachtet. Alle drei Tiere waren zwischen 2 1/2 und 3 1/2 Monate alt und lebten in einer Höhe von über 2800 m, in einer Gegend, in welcher Jodmangel besteht. Alle drei Tiere zeigten ausserdem Hypertrophie des rechten Ventrikels, erstes Stadium der “Brisket Disease”. Höhe und ein Mangelfaktor (Jodmangel, Kupfermangel?) werden als mögliche Ursache vermutet, jedoch fehlen noch die nötigen Ergänzungsuntersuchungen.
{"title":"[Three cases of dissecting aneurysm in calves in Ecuador].","authors":"E Teuscher, E Vásconez López","doi":"10.1177/030098586900600607","DOIUrl":"https://doi.org/10.1177/030098586900600607","url":null,"abstract":"Zusammenfassung Es werden drei Fälle von Aneurysma dissecans beim Kalb beschrieben. Zwei Tiere starben an Haemopericardium, ein Tier an Haemothorax. Bei einem Tier wurden am Vorabend Kolikerscheinungen beobachtet. Alle drei Tiere waren zwischen 2 1/2 und 3 1/2 Monate alt und lebten in einer Höhe von über 2800 m, in einer Gegend, in welcher Jodmangel besteht. Alle drei Tiere zeigten ausserdem Hypertrophie des rechten Ventrikels, erstes Stadium der “Brisket Disease”. Höhe und ein Mangelfaktor (Jodmangel, Kupfermangel?) werden als mögliche Ursache vermutet, jedoch fehlen noch die nötigen Ergänzungsuntersuchungen.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 6","pages":"538-45"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600607","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15350945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600609
W Jakob, K Krieg, M Hilgenfeld
Zusammenfassung In den untersuchten amyloiden, fibrinoiden und hyalinen Gefässwandablagerungen konnten in wechselnder Intensität primäre Aminogruppen, Sulfhydryl- und Disulfidgruppen sowie die Aminosäuren Tryptophan, Tyrosin und Arginin histochemisch dargestellt werden. Da Tryptophan, Tyrosin und Cystin/Cystein verhaltnismassig reichlich in den Plasmaproteinen vorkommen, ist anzunehmen, dass Bluteiweisskörper einen wesentlichen Bestandteil dieser Ablagerungen darstellen. Eine morphologische Unterscheidung des Amyloids, Fibrinoids und Hyalins kann auf Grund des qualitativ-histochemischen Nachweises dieser Aminosäuren nicht vorgenommen werden, weil sie in allen 3 Substraten vorkommen.∗
{"title":"[Comparative studies on the histochemical behavior of amyloid, fibrinoid and hyalin precipitates in the walls of blood vessels of various mammals and birds. 1. Proteins].","authors":"W Jakob, K Krieg, M Hilgenfeld","doi":"10.1177/030098586900600609","DOIUrl":"https://doi.org/10.1177/030098586900600609","url":null,"abstract":"Zusammenfassung In den untersuchten amyloiden, fibrinoiden und hyalinen Gefässwandablagerungen konnten in wechselnder Intensität primäre Aminogruppen, Sulfhydryl- und Disulfidgruppen sowie die Aminosäuren Tryptophan, Tyrosin und Arginin histochemisch dargestellt werden. Da Tryptophan, Tyrosin und Cystin/Cystein verhaltnismassig reichlich in den Plasmaproteinen vorkommen, ist anzunehmen, dass Bluteiweisskörper einen wesentlichen Bestandteil dieser Ablagerungen darstellen. Eine morphologische Unterscheidung des Amyloids, Fibrinoids und Hyalins kann auf Grund des qualitativ-histochemischen Nachweises dieser Aminosäuren nicht vorgenommen werden, weil sie in allen 3 Substraten vorkommen.∗","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 6","pages":"557-67"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600609","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15302103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600104
H J Norris, H B Taylor, F M Garner
The clinical and pathologic features of 26 neoplasms derived from gonadal stroma of hovine species were analyzed. Two types were identified-1 a typical granulosa tumor, the other having a Sertoli pattern. The 13 granulosa tumors occurred in adult animals, 2 of which exhibited nymphomania. Nine of the 13 had metastasized by the time of discovery. The Sertoli type of tumor also occurred in adult animals. Estrinizing effects were more common in these, as the endometrium had varying degrees of hyperplasia or thickening in 7 instances, and 1 animal had persistent estrus. None had spread beyond the ovary. The Sertoli type was thought to be more closely related to granulosa tumors than arrhenoblastomas because it was associated with estrinizing rather than virilizing effect, all of them lacked Leydig cells, some had overlapping microscopic patterns with granulosa tumors. and a Sertoli arrangement could be identified that was similar to areas in early graafian follicles and atretic follicles. They merit separation from granulosa tumors because of their distinctive histological pattern and because of their much more benign clinical behavior.
{"title":"Comparative pathology of ovarian neoplasms. II. Gonadal stromal tumors of bovine species.","authors":"H J Norris, H B Taylor, F M Garner","doi":"10.1177/030098586900600104","DOIUrl":"https://doi.org/10.1177/030098586900600104","url":null,"abstract":"The clinical and pathologic features of 26 neoplasms derived from gonadal stroma of hovine species were analyzed. Two types were identified-1 a typical granulosa tumor, the other having a Sertoli pattern. The 13 granulosa tumors occurred in adult animals, 2 of which exhibited nymphomania. Nine of the 13 had metastasized by the time of discovery. The Sertoli type of tumor also occurred in adult animals. Estrinizing effects were more common in these, as the endometrium had varying degrees of hyperplasia or thickening in 7 instances, and 1 animal had persistent estrus. None had spread beyond the ovary. The Sertoli type was thought to be more closely related to granulosa tumors than arrhenoblastomas because it was associated with estrinizing rather than virilizing effect, all of them lacked Leydig cells, some had overlapping microscopic patterns with granulosa tumors. and a Sertoli arrangement could be identified that was similar to areas in early graafian follicles and atretic follicles. They merit separation from granulosa tumors because of their distinctive histological pattern and because of their much more benign clinical behavior.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 1","pages":"45-58"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600104","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16889668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600402
C C Capen, S L Martin
Neoplasms of the pancreatic islets in 6 of 9 dogs were functionally active and were associated with a syndrome of hyperinsulinism. The serum concentration of immunoreactive insulin in a dog with beta-cell carcinoma was increased compared to normal dogs. Metastases in the liver and lymph nodes remained functionally active and were responsive to tolbutamide following excision of the primary neoplasm. The cells comprising functional islet-cell neoplasms had ultrastructural and histochemical characteristics of beta cells. At the level of ultrastructure the neoplastic cells had definitive evidence of secretory activity and the organelles concerned with protein synthesis were well developed. Secretory granules were numerous and had unique bar-shaped or round internal cores with a wide electron-lucid halo, characteristic of the insulin-secreting cell of the canine pancreas.
{"title":"Hyperinsulinism in dogs with neoplasia of the pancreatic islets. A clinical, pathologic, and ultrastructural study.","authors":"C C Capen, S L Martin","doi":"10.1177/030098586900600402","DOIUrl":"https://doi.org/10.1177/030098586900600402","url":null,"abstract":"Neoplasms of the pancreatic islets in 6 of 9 dogs were functionally active and were associated with a syndrome of hyperinsulinism. The serum concentration of immunoreactive insulin in a dog with beta-cell carcinoma was increased compared to normal dogs. Metastases in the liver and lymph nodes remained functionally active and were responsive to tolbutamide following excision of the primary neoplasm. The cells comprising functional islet-cell neoplasms had ultrastructural and histochemical characteristics of beta cells. At the level of ultrastructure the neoplastic cells had definitive evidence of secretory activity and the organelles concerned with protein synthesis were well developed. Secretory granules were numerous and had unique bar-shaped or round internal cores with a wide electron-lucid halo, characteristic of the insulin-secreting cell of the canine pancreas.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 4","pages":"309-41"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600402","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15991899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600408
J R Lindsey, L R Wharton, J D Woodruff, H J Baker
A spontaneous neoplasm (the fourth reported from the female reproductive organs of the rhesus monkey) is described-an intrauterine choriocarcinoma with massive pulmonary metastasis.
{"title":"Intrauterine choriocarcinoma in a rhesus monkey.","authors":"J R Lindsey, L R Wharton, J D Woodruff, H J Baker","doi":"10.1177/030098586900600408","DOIUrl":"https://doi.org/10.1177/030098586900600408","url":null,"abstract":"A spontaneous neoplasm (the fourth reported from the female reproductive organs of the rhesus monkey) is described-an intrauterine choriocarcinoma with massive pulmonary metastasis.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 4","pages":"378-84"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600408","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16074469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}