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The case against renal dose dopamine in the pediatric intensive care unit. 小儿重症监护病房肾剂量多巴胺的案例。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00014
Bonnie Anne Rice, Marla C Tanski

The use of dopamine for the treatment of renal insufficiency has become a controversial issue. Dopamine exerts its effects on the kidneys through activity on the catecholamine receptors and by its diuretic and natriuretic properties. Utilization of renal dose dopamine to increase renal blood flow has been considered beneficial for preservation of renal function for over 30 years. The hypothesis proposed was that increasing urine volume must indicate improving renal function, particularly in oliguric patients. However, recent clinical trials in adult and pediatric patients have not only failed to demonstrate any benefit, but have also suggested that this therapy may actually have detrimental effects. This article reviews basic pharmacology and physiologic effects and the potential adverse effects of "renal dose dopamine." It also examines the results of clinical trials, in both pediatric and adult patients, that evaluated its usefulness for the treatment of renal insufficiency.

使用多巴胺治疗肾功能不全已经成为一个有争议的问题。多巴胺对肾脏的作用是通过儿茶酚胺受体的活性以及它的利尿和利钠特性。30多年来,利用肾剂量多巴胺增加肾血流量被认为有利于保存肾功能。提出的假设是,尿量增加一定表明肾功能改善,特别是在少尿患者中。然而,最近在成人和儿科患者中进行的临床试验不仅没有显示出任何益处,而且还表明这种疗法实际上可能有有害的影响。本文综述了“肾剂量多巴胺”的基本药理和生理作用以及潜在的不良反应。它还检查了儿科和成人患者的临床试验结果,评估了其治疗肾功能不全的有效性。
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引用次数: 3
Cardiovascular surgeon and acute care nurse practitioner: collaboration on postoperative outcomes. 心血管外科医生和急症护理护士:术后结果的合作。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00005
Susan C Meyer, Linda J Miers

Changes occurring in the healthcare environment require healthcare delivery systems to provide high quality care services with increased efficiency and cost-effectiveness. Healthcare systems are encouraged to use less expensive care providers for medical management responsibilities while maintaining or increasing quality of patient care. Accompanying the changes in healthcare delivery modes is the parallel rise in patient acuity levels related to chronic illnesses of patients admitted for cardiac services such as cardiovascular surgeries. This retrospective, 2-group comparison study examined patient and economic outcomes between 2 groups of adult patients for whom postoperative cardiovascular care was directed by either cardiovascular surgeons alone or cardiovascular surgeons in collaboration with acute care nurse practitioners. Outcome measures included length of stay and cost for an episode of care. Findings revealed that when cardiovascular surgeons, in collaboration with acute care nurse practitioners, directed postoperative care, the length of stay decreased 1. 91 days and total cost decreased 5,038.91 dollars per patient.

医疗环境的变化要求医疗服务系统以更高的效率和成本效益提供高质量的医疗服务。鼓励医疗保健系统使用较便宜的医疗服务提供者承担医疗管理责任,同时保持或提高患者护理质量。随着医疗服务模式的改变,接受心血管手术等心脏服务的慢性疾病患者的敏锐度也相应提高。这项回顾性的两组比较研究检查了两组成年患者的患者和经济结果,这两组患者的术后心血管护理由心血管外科医生单独指导或由心血管外科医生与急症护理护士合作指导。结果测量包括住院时间和一次护理的费用。研究结果显示,当心血管外科医生与急症护理护士合作指导术后护理时,住院时间缩短了1。91天,每个病人的总费用减少了5038.91美元。
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引用次数: 79
Outcomes of an infection prevention project focusing on hand hygiene and isolation practices. 以手部卫生和隔离措施为重点的感染预防项目的成果。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00002
Daleen Aragon, Mary Lou Sole, Scott Brown

Nosocomial infections are a major health problem for hospitalized patients and their families. Since the 1800s, hand hygiene has been recognized as the single best method to prevent the spread of pathogens and nosocomial infections. Despite this fact, many healthcare workers do not adhere to hand hygiene policies. The Centers for Disease Control and Prevention issued a guideline for hand hygiene practices in 2002. Multifaceted approaches to improve hand hygiene have been shown to increase compliance among healthcare workers and subsequently reduce infections. A performance improvement project was initiated to implement this guideline and other strategies to prevent nosocomial infection. This article summarizes the performance improvement processes and the preliminary outcomes on adherence to infection prevention policies related to hand hygiene and isolation practices. Clinically and statistically significant increases were noted for hand hygiene prior to patient care and in wearing masks when indicated. Nurses and patient care technicians had the greatest increases in compliance. Increases in hand hygiene after patient contact and wearing of gown and gloves were also noted, but results were not statistically significant. Nosocomial infection rates from antibiotic-resistant organisms decreased in the first surveillance, but rates increased during the 1-year surveillance. Consumption of alcohol-based foam disinfectant doubled from baseline. Findings are consistent with other published studies. The project will continue with further reinforcement and education over the second year.

医院感染是住院病人及其家属的主要健康问题。自19世纪以来,手卫生一直被认为是防止病原体传播和医院感染的唯一最佳方法。尽管如此,许多卫生保健工作者没有遵守手卫生政策。2002年,美国疾病控制与预防中心发布了一份手部卫生指南。改善手卫生的多方面方法已被证明可提高卫生保健工作者的依从性,并随后减少感染。开展了一项绩效改进项目,以实施这一指导方针和其他预防医院感染的战略。本文总结了在遵守与手部卫生和隔离措施有关的感染预防政策方面的绩效改进过程和初步结果。在临床和统计上,患者护理前的手部卫生和指征时佩戴口罩的情况显著增加。护士和病人护理技术人员的依从性增加最多。也注意到在患者接触和穿着长袍和手套后手部卫生的增加,但结果没有统计学意义。抗生素耐药菌的医院感染率在第一次监测中下降,但在1年监测期间上升。酒精泡沫消毒剂的消费量比基线增加了一倍。研究结果与其他已发表的研究结果一致。该项目将在第二年继续加强和教育。
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引用次数: 63
Oncological emergencies in the pediatric intensive care unit. 儿科重症监护室的肿瘤紧急情况。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00013
Cathy Haut

The overall 5-year survival rate of children with cancer has now reached 77%, an increase of about 45% in the past 25 years. Newer therapies, including hematopoietic cell transplantation and cutting edge chemotherapeutics evolving in the form of molecular and biological cell targeted agents, are being researched and developed and are responsible for the change in survival rates over time. Also, despite the national trend toward hospice and palliative care, children with chronic and life threatening illnesses, continue to die in the hospital setting, often in the intensive care unit. Previous studies of children with complications of cancer and its therapy document poor outcomes among those who do require intensive care. These trends are changing, however, currently leaving a hopeful, optimistic view of the outcome in children with cancer complications admitted to the pediatric intensive care unit. It is imperative that nurses and intensive care staff understand pediatric cancer and its potential emergent consequences in order to respond to the symptoms of life threatening events.

癌症儿童的总体5年生存率现已达到77%,在过去25年中增加了约45%。新的治疗方法,包括造血细胞移植和以分子和生物细胞靶向药物形式发展的尖端化疗,正在研究和开发中,并且随着时间的推移,生存率发生了变化。此外,尽管全国趋向于临终关怀和姑息治疗,但患有慢性和危及生命疾病的儿童继续在医院环境中死亡,通常是在重症监护病房。先前对患有癌症并发症的儿童及其治疗的研究表明,那些确实需要重症监护的儿童预后不佳。这些趋势正在改变,然而,目前留下了一个充满希望的,乐观的观点,结果与癌症并发症的儿童入住儿科重症监护病房。护士和重症监护人员必须了解儿童癌症及其潜在的紧急后果,以便对危及生命的事件的症状作出反应。
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引用次数: 21
"It's the people that make the environment good or bad": the patient's experience of the acute care hospital environment. “是人决定了环境的好坏”:病人对急症护理医院环境的体验。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00006
Mona Shattell, Beverly Hogan, Sandra P Thomas

A review of contemporary nursing research reveals a tendency to focus on select aspects of the hospital environment such as noise, light, and music. Although studies such as these shed light on discrete aspects of the hospital environment, this body of literature contributes little to an understanding of the entirety of that world as the patient in the sickbed experiences it. The purpose of the study detailed in this article was to describe the patient's experience of the acute care hospital environment. Nondirective, in-depth phenomenological interviews were conducted, then transcribed verbatim, and analyzed for themes. Against the backdrop of "I lived and that's all that matters," there were 3 predominant themes in patients' experience of the acute care environment: (1) disconnection/connection, (2) fear/less fear, and (3) confinement/freedom. In this environment, human-to-human contact increased security and power in an environment that was described as sterile, disorienting, and untrustworthy. Acute and critical care nurses and other caregivers can use the findings to create less noxious hospital environments.

对当代护理研究的回顾表明,人们倾向于关注医院环境的某些方面,如噪音、光线和音乐。尽管诸如此类的研究揭示了医院环境的离散方面,但这些文献对理解病人在病床上经历的整个世界贡献不大。本文详细研究的目的是描述患者对急症护理医院环境的体验。进行非指导性、深入的现象学访谈,然后逐字记录,并分析主题。在“我活着,这才是最重要的”的背景下,病人对急症护理环境的体验有三个主要主题:(1)断开/连接,(2)恐惧/减少恐惧,(3)禁闭/自由。在这种环境中,人与人之间的接触在一个被描述为贫瘠、迷失方向和不可信的环境中增加了安全和权力。急症和重症护理护士和其他护理人员可以利用这些发现来创造更少有害的医院环境。
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引用次数: 33
The use of common continuous monitoring parameters: a quality indicator for critically ill patients with sepsis. 常用连续监测参数的使用:脓毒症危重患者的质量指标
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00004
Karen K Giuliano, Ruth Kleinpell

Sepsis is a common source of morbidity and mortality among critically ill patients, and targeting measures to promote early recognition and treatment of sepsis is at the forefront of many critical care initiatives. Starting formally in 1992, with the publication of the definitions of sepsis, continuous monitoring of several common physiologic parameters, including electrocardiogram, blood pressure, and oxygen saturation, have been advocated as important in the early identification and treatment of patients with sepsis. The descriptive study detailed in this article was conducted to assess the perceptions and clinical continuous physiologic monitoring practices of experienced critical care clinicians with regard to their use of common physiologic monitoring parameters in the care of patients with sepsis. A convenience sample of 100 physicians and 517 nurses completed a 20-item survey assessing perceptions and clinical monitoring practices related to the care of patients with sepsis. Results indicated that the basic parameters of electrocardiogram, invasive blood pressure, pulmonary arterial catheter monitoring, and oxygen saturation all have value in the recognition and treatment of patients with sepsis. The majority of clinicians used these parameters routinely and felt they were necessary for patient care. These results indicate that clinical practice is in concordance with current practice recommendations.

脓毒症是危重症患者发病率和死亡率的常见来源,有针对性的措施促进早期识别和治疗脓毒症是许多危重症护理倡议的前沿。1992年,随着脓毒症定义的正式发布,连续监测几个常见的生理参数,包括心电图、血压和血氧饱和度,被认为是脓毒症患者早期识别和治疗的重要指标。本文中详细的描述性研究是为了评估经验丰富的重症监护临床医生在脓毒症患者护理中使用常见生理监测参数的认知和临床连续生理监测实践。100名医生和517名护士完成了一项20项调查,评估了与脓毒症患者护理相关的认知和临床监测实践。结果表明,心电图、有创血压、肺动脉导管监测、血氧饱和度等基本参数对脓毒症患者的识别和治疗均有价值。大多数临床医生常规使用这些参数,并认为它们对患者护理是必要的。这些结果表明临床实践与目前的实践建议是一致的。
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引用次数: 12
Quality improvement in backrest elevation: improving outcomes in critical care. 提高靠背抬高的质量:改善重症监护的结果。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00003
Mary Jo Grap, Cindy L Munro

The positioning of critically ill patients is an independent nursing decision, often has multiple rationales, and may significantly affect morbidity and mortality. Recent evidence suggests that backrest elevation in critically ill patients may reduce ventilator-associated pneumonia. However, use of recommended levels of backrest elevation is infrequent in the critical care environment. In addition, published guidelines for backrest elevation to reduce pneumonia conflict with those for protecting skin integrity. This article reviews the benefits and complications of backrest elevation, data related to current positioning practices, and recommendations for backrest elevation. A quality improvement process to guide evidence-based care related to backrest positioning is also described.

危重病人的定位是一项独立的护理决策,往往有多种理由,并可能显著影响发病率和死亡率。最近的证据表明,危重患者抬高靠背可减少呼吸机相关性肺炎。然而,在重症监护环境中,使用推荐的靠背高度水平并不常见。此外,已发表的关于抬高靠背以减少肺炎的指南与保护皮肤完整性的指南相冲突。这篇文章回顾了靠背抬高的好处和并发症,与当前定位实践相关的数据,以及对靠背抬高的建议。质量改进过程,以指导循证护理相关的靠背定位也被描述。
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引用次数: 20
The changing face of critical care medicine: nurse practitioners in the pediatric intensive care unit. 重症监护医学的变化:儿科重症监护病房的护士从业人员。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00008
Shirley Molitor-Kirsch, Lisa Thompson, Lisa Milonovich

Over the last 50 years, healthcare has undergone countless changes. Some of the important changes in recent years have been budget cuts, decreased resident work hours, and increased patient acuity. The need for additional clinical expertise at the bedside has resulted in nurse practitioners becoming an integral part of the healthcare delivery team. To date, little has been published regarding the role of the nurse practitioners in intensive care units. This article outlines how one pediatric hospital has successfully utilized nurse practitioners in the intensive care unit.

在过去的50年里,医疗保健经历了无数的变化。近年来的一些重要变化是预算削减,住院医生工作时间减少,病人的视力提高。对床边额外临床专业知识的需求导致执业护士成为医疗保健服务团队不可或缺的一部分。迄今为止,很少有关于在重症监护病房护士从业人员的作用发表。这篇文章概述了一个儿科医院如何成功地利用护士从业人员在重症监护室。
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引用次数: 25
Munchausen syndrome by proxy: a case report. 孟乔森综合症的代理:一个病例报告。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00009
Holly S Lieder, Sharon Y Irving, Rizalina Mauricio, Jeanine M Graf

Munchausen syndrome by proxy is difficult to diagnose unless healthcare providers are astute to its clinical features and management. A case is presented to educate nurses and advanced practice nurses, of the nursing, medical, legal, and social complexities associated with Munchausen syndrome by proxy. This article also provides a brief review of the definition of Munchausen syndrome by proxy, its epidemiology, common features of the perpetrator, implications for healthcare personnel, and the legal and international ramifications of Munchausen syndrome by proxy.

除非医疗保健提供者对其临床特征和管理非常敏感,否则代理孟乔森综合征很难诊断。本文提出了一个案例,以教育护士和高级执业护士,与代理孟乔森综合征相关的护理,医疗,法律和社会复杂性。本文还简要回顾了代理蒙乔森综合征的定义、流行病学、行为人的共同特征、对医护人员的影响以及代理蒙乔森综合征的法律和国际后果。
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引用次数: 6
Hyperosmolar therapy in the treatment of severe head injury in children: mannitol and hypertonic saline. 儿童重型颅脑损伤的高渗治疗:甘露醇和高渗盐水。
Pub Date : 2005-04-01 DOI: 10.1097/00044067-200504000-00011
James M Knapp

Traumatic brain injury is the result of a primary, acute injury and is complicated by the development of secondary injury due to hypotension and hypoxia. Cerebral edema due to brain injury compromises the delivery of essential nutrients and alters normal intracranial pressure. The Monroe-Kellie Doctrine defines the principles of intracranial pressure homeostasis. Treatment for intracranial hypertension is aimed at reducing the volume of 1 of the 3 intracranial compartments, brain tissue, blood, and cerebrospinal fluid. Hyperosmolar therapy is one treatment intervention in the care of patients with severe head injury resulting in cerebral edema and intracranial hypertension. The effect of hyperosmolar solutions on brain tissue was first studied nearly 90 years ago. Since that time, mannitol has become the most widely used hyperosmolar solution to treat elevated intracranial pressure. Increasingly, hypertonic saline solutions are being used as an adjunct to mannitol in basic science research and clinical studies. Hyperosmolar solutions are effective in reducing elevated intracranial pressure through 2 distinct mechanisms: plasma expansion with a resultant decrease in blood hematocrit, reduced blood viscosity, and decreased cerebral blood volume; and the creation of an osmotic gradient that draws cerebral edema fluid from brain tissue into the circulation. The pediatric section of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies adapted previously published guidelines for the treatment of adult brain injury into guidelines for the treatment of children with traumatic brain injury. These guidelines offer recommendations for the management of children with severe head injury, including the use of mannitol and hypertonic saline to treat intracranial hypertension. Acute and critical care pediatric advanced practice nurses caring for children with severe head injury should be familiar with management guidelines and the use of hyperosmolar solutions. The purpose of this article is to assist the advanced practice nurse in understanding the role of hyperosmolar therapy in the treatment of pediatric traumatic brain injury and review current guidelines for the use of mannitol and hypertonic saline.

外伤性脑损伤是原发性急性损伤的结果,并因低血压和缺氧而继发性损伤的发展而复杂化。脑损伤引起的脑水肿损害了必需营养物质的输送,并改变了正常的颅内压。门罗-凯利学说定义了颅内压稳态的原理。颅内高压的治疗旨在减少颅内三腔室之一、脑组织、血液和脑脊液的体积。高渗疗法是重型颅脑损伤致脑水肿和颅内高压患者护理中的一种治疗干预措施。高渗溶液对脑组织的影响在近90年前首次被研究。从那时起,甘露醇成为治疗颅内压升高最广泛使用的高渗溶液。在基础科学研究和临床研究中,越来越多地使用高渗盐水溶液作为甘露醇的辅助剂。高渗溶液通过两种不同的机制有效降低颅内压升高:血浆扩张导致血液红细胞压积降低,血液粘度降低,脑血容量减少;还有一种渗透梯度的产生将脑水肿液从脑组织引入血液循环。重症医学学会儿科分会和世界儿科重症监护学会联合会将先前出版的成人脑损伤治疗指南改编为创伤性脑损伤儿童治疗指南。这些指南为严重颅脑损伤儿童的治疗提供了建议,包括使用甘露醇和高渗盐水治疗颅内高压。急症和危重症儿科高级护理护士护理严重头部损伤的儿童应该熟悉管理指南和使用高渗溶液。本文的目的是帮助高级执业护士了解高渗疗法在儿童创伤性脑损伤治疗中的作用,并回顾目前使用甘露醇和高渗盐水的指南。
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引用次数: 97
期刊
AACN clinical issues
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