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In older adults, RSV prefusion F vaccine reduced hospitalization for RSV-related respiratory tract disease vs. no vaccine. 在老年人中,与未接种相比,RSV预融合F疫苗减少了RSV相关呼吸道疾病的住院率。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2026-01-06 DOI: 10.7326/ANNALS-25-05113-JC
Henry S Sacks

Clinical impact ratings: GIM/FP/GP: [Formula: see text] Geriatrics: [Formula: see text] Infectious Disease: [Formula: see text] Pulmonology: [Formula: see text].

临床影响评级:GIM/FP/GP:[公式:见文]老年病学:[公式:见文]传染病学:[公式:见文]肺病学:[公式:见文]。
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引用次数: 0
Iron Deficiency Anemia. 缺铁性贫血。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2026-01-13 DOI: 10.7326/ANNALS-25-04416
Kylee L Martens, Thomas G DeLoughery

Iron deficiency anemia (IDA) is caused by iron deficiency, a common yet underrecognized clinical entity. Populations at greatest risk include children, menstruating and pregnant persons, and people of low socioeconomic status. Timely diagnosis and management of iron deficiency are key to preventing IDA and require thorough assessment of the underlying cause and appropriate iron repletion through either oral or parenteral therapy. Blood transfusion does not provide adequate elemental iron but is sometimes indicated along with iron therapy in patients with cardiovascular compromise, active bleeding, or severe anemia where more rapid correction is warranted. Alternative causes of anemia can be differentiated by red blood cell morphology and reticulocyte count and should be considered if anemia persists despite adequate repletion of iron stores.

缺铁性贫血(IDA)是由缺铁引起的,这是一种常见但未被充分认识的临床实体。风险最大的人群包括儿童、经期和孕妇以及社会经济地位较低的人。及时诊断和管理缺铁是预防IDA的关键,需要彻底评估潜在原因,并通过口服或肠外治疗适当补充铁。输血不能提供足够的元素铁,但有时在有心血管疾病、活动性出血或严重贫血的患者中,需要更快速的纠正时,与铁治疗一起使用。贫血的其他原因可以通过红细胞形态和网织红细胞计数来区分,如果在铁储备充足的情况下贫血仍然存在,则应考虑贫血。
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引用次数: 0
Persistence of Effects of Behavioral Interventions on Reducing Overuse of Care in Older Patients After Discontinuation. 行为干预对减少老年患者停药后过度使用护理的持续作用。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 DOI: 10.7326/ANNALS-25-04163
Ivan David Lozada-Martinez, Juan-Manuel Anaya
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引用次数: 0
Implementation of Social Needs Screening and Intervention in Primary Care : A Systematic Review of Program-Level Determinants. 社会需求筛查和干预在初级保健中的实施:项目层面决定因素的系统回顾。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-11 DOI: 10.7326/ANNALS-25-00308
Eva Chang, Iridian Guzman, Nicole Glowacki, Rasha Khatib

Background: Health care systems are investing significant resources in social needs screening and intervention programs.

Purpose: To understand characteristics contributing to implementation of social needs screening and intervention programs in primary care.

Data sources: CINAHL, Cochrane, Ovid, PubMed, and Scopus (January 2015 to April 2025).

Study selection: U.S.-based programs using structured tools to screen adult patients for at least 1 Healthcare Effectiveness Data and Information Set measure (food insecurity, transportation, and housing insecurity) and addressing social needs in primary care settings.

Data extraction: Program characteristics; screening and intervention implementation processes; and patient screening, intervention, clinical, and health care use outcomes.

Data synthesis: The review included 23 studies. Seventeen reported on screening outcomes, 11 in populations characterized by a particular condition or health care use and 6 in the general population. Programs with the highest percentage of patients screened focused on fewer than 500 patients with a particular condition or health care use and received support from additional staff or volunteers (4 of 17 studies). Of patients screened, 10.1% to 100% reported a social need. Eleven studies reported on receipt of assistance or resources, with a higher percentage of patients receiving assistance or resources among programs that targeted a smaller population. Few studies reported clinical and health care use outcomes, with mixed findings.

Limitations: Few studies had complete reporting of screening and intervention rates and outcomes. Program characteristics and other screening and intervention processes varied across and within studies.

Conclusion: Social needs programs focused on smaller, targeted populations were more likely to screen and assist a higher percentage of patients. Programs with adequate staffing may also screen a higher proportion of patients. However, evidence is mixed, particularly for clinical and health care use outcomes. Considerable differences among screening and intervention programs preclude simple suggestions for universal implementation.

Primary funding source: Live Well Intramural Pilot Grant Program. (PROSPERO: CRD42023431151).

背景:卫生保健系统在社会需求筛选和干预项目上投入了大量资源。目的:了解有助于在初级保健中实施社会需求筛查和干预方案的特征。数据来源:CINAHL、Cochrane、Ovid、PubMed、Scopus(2015年1月- 2025年4月)。研究选择:以美国为基础的项目,使用结构化工具筛选成人患者至少1项医疗保健有效性数据和信息集测量(食品不安全、交通不安全和住房不安全),并解决初级保健机构的社会需求。数据提取:节目特点;筛查和干预措施实施过程;以及患者筛查、干预、临床和医疗保健使用结果。资料综合:本综述包括23项研究。17例报告了筛查结果,11例在具有特定疾病或保健使用特征的人群中,6例在普通人群中。筛查患者比例最高的项目集中在500名以下患有特定疾病或使用医疗保健的患者身上,并得到了额外工作人员或志愿者的支持(17项研究中的4项)。在接受筛查的患者中,10.1%至100%报告有社会需求。11项研究报告了获得援助或资源的情况,在针对较小人群的项目中,获得援助或资源的患者比例较高。很少有研究报告临床和卫生保健使用结果,结果好坏参半。局限性:很少有研究完整地报告了筛查和干预率和结果。项目特征和其他筛选和干预过程在不同的研究中有所不同。结论:社会需求项目专注于较小的目标人群,更有可能筛选和帮助更高比例的患者。配备足够人员的项目也可以筛查更高比例的患者。然而,证据是混合的,特别是在临床和卫生保健使用结果方面。筛查和干预方案之间存在巨大差异,因此无法提出普遍实施的简单建议。主要资金来源:“好好生活”校内试点资助计划。(普洛斯彼罗:CRD42023431151)。
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引用次数: 0
Web Exclusive. Annals On Call - Mediterranean Diet in the Management of Irritable Bowel Syndrome. 随叫随到——地中海饮食对肠易激综合征的治疗。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2026-01-06 DOI: 10.7326/ANNALS-25-05558-OC
Robert M Centor, Imran Aziz
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引用次数: 0
Advancing Health Care Professional Well-Being: Progress in the Face of Imperfection. 促进卫生保健专业福祉:面对不完美的进步。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-18 DOI: 10.7326/ANNALS-25-04277
Colin P West
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引用次数: 0
Revaluing Physician Services: CMS Has Some (but Not All) Answers. 重新评估医生服务:CMS有一些(但不是全部)答案。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2025-11-04 DOI: 10.7326/ANNALS-25-03638
William Fox
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引用次数: 0
In older adults, high- vs. standard-dose influenza vaccine reduced hospitalization for influenza or pneumonia. 在老年人中,与标准剂量相比,高剂量流感疫苗减少了流感或肺炎的住院治疗。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2026-01-06 DOI: 10.7326/ANNALS-25-05209-JC
Steven Y C Tong, Katherine B Gibney

Clinical impact ratings: GIM/FP/GP: [Formula: see text] Public Health: [Formula: see text].

临床影响评级:GIM/FP/GP:[公式:见文本]公共卫生:[公式:见文本]。
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引用次数: 0
Introducing I.M. Matters News. 介绍im时事新闻。
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 Epub Date: 2026-01-06 DOI: 10.7326/ANNALS-25-05046-IM
Christine Laine, Jennifer Kearney-Strouse
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引用次数: 0
Web Exclusive. Annals Consult Guys - Recurrent Atrial Fibrillation: The "Why?" and "When?" of "What to Do?" 年鉴咨询男士-复发性心房颤动:“为什么?”和“何时?”的“怎么做?”
IF 15.2 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-01 DOI: 10.7326/ANNALS-26-00134-CG
Howard H Weitz, Geno J Merli, Gregory Lip, Daniel Frisch
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引用次数: 0
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