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Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera最新文献

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Molecular Markers for Colorectal Cancer 结直肠癌的分子标记
Pub Date : 2013-03-14 DOI: 10.1024/1023-9332.7.6.243
Scheunemann, Hosch, Kutup, Izbicki
Die Einfuhrung von immunhisto-/zytochemischen und molekularbiologischen bzw. zytogenetischen Methoden in der onkologische Forschung hat trotz vieler nach wie vor bestehender offener Fragen insgesamt zu einem besseren Verstandnis der genetischen Ursachen der Tumorentstehung gefuhrt. Daruber hinaus ergaben sich in verschiedenen Studien Hinweise fur eine prognostische Relevanz von bestimmten (zyto)genetischen Veranderungen bzw. residualen Tumorzellen in Lymphknoten oder Knochenmark. Bevor diese Untersuchungen jedoch in den klinischen Alltag Einzug halten und therapeutische Konsequenzen abgeleitet werden konnen, sind weitere prospektive Studien mit groaen Patientenfallzahlen sowie vereinheitlichte und methodologisch praktikable Untersuchungstechniken zu fordern.
免疫学/细胞化学和分子生物学及细胞遗传方法此外,不同研究显示某些淋巴结或骨髓的基因增生和冠状瘤细胞有关联性。但在这些研究纳入日常生活并产生治疗效果之前,我们需要更多预先假设的病人病例数量研究,以及统一和合乎逻辑的研究技术。
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引用次数: 0
[Challenging perioperative anticoagulation in a patient with Budd-Chiari syndrome and heparin-induced thrombocytopenia]. [Budd-Chiari综合征合并肝素诱导的血小板减少症患者围手术期抗凝治疗的挑战]。
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.7.3.141
E. Gygax, P. Berdat, T. Carrel
We report on a patient suffering from Budd-Chiari disease who developed heparin-induced thrombocytopenia preoperatively. Dorsocranial liver resection and hepatoatrial anastomosis were performed with the extracorporeal circulation and perioperative anticoagulation was achieved with r-hirudin. Surprisingly, thrombus formation was observed in the venous reservoir although intraoperative anticoagulation values were within the targeted level. An additional bolus of hirudin and rinsing the reservoir allowed unproblematic discontinuation of the cardiopulmonary bypass.
我们报告了一个患有布-基亚里病的患者,他术前出现了肝素诱导的血小板减少症。经体外循环行背颅肝切除及肝房吻合,围术期应用水蛭素抗凝。令人惊讶的是,尽管术中抗凝值在目标水平内,但在静脉储层中观察到血栓形成。一个额外的水蛭素丸和冲洗水库允许无问题停止体外循环。
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引用次数: 0
Posttraumatic Pancreatic Pseudocyst in Children - Case Report and Discussion 儿童创伤后胰腺假性囊肿病例报告及讨论
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.7.5.225
Rosenthal, Vogelbach
Pankreaspseudozysten sind selten im Kindesalter. Sie sind in 80% der Falle traumatisch bedingt. Anhand eines Fallberichtes diskutieren wir die Therapie von Pankreasverletzungen und der daraus resultierenden Pseudozysten beim Kind.
胰腺炎小时候很罕见但80%的陷阱都是由创伤造成的根据它的案例,我们讨论医治胰腺癌…和因此产生的假性囊肿。
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引用次数: 1
[Monstrous, retroperitoneal liposarcoma--a case report]. [畸形腹膜后脂肪肉瘤1例报告]。
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.7.1.32
M. Niedergethmann, R. Hildenbrand, M. Winkler
Liposarcomas comprise about 20% of soft tissue sarcomas and occur in 14% in the retroperitoneal space originating in one third from the perirenal fat. The case of a patient with an extraordinary huge, resectable, well-differentiated retroperitoneal liposarcoma is reported. The presenting symptoms were abdominal pain and distension as well as weight gain. Magneticresonance imaging revealed a huge retroperitoneal tumor suspected of well-differentiated liposarcoma. Curative resection of the tumor could be obtained. Only 50% of all tumors are excised without residual tumor and recurrence, occurring in 90% after 10 years, is the main therapeutic challenge. Since neoadjuvant and adjuvant therapy as well as intraoperative radiotherapy failed to prove prognostic value, curative resection remains the main treatment for primary and recurrent liposarcomas.
脂肪肉瘤约占软组织肉瘤的20%,发生在腹膜后间隙的占14%,起源于肾周脂肪的三分之一。我们报告了一例巨大的、可切除的、分化良好的腹膜后脂肪肉瘤。主要症状为腹痛、腹胀和体重增加。磁共振成像显示一个巨大的腹膜后肿瘤疑似高分化脂肪肉瘤。可获得肿瘤的根治性切除。只有50%的肿瘤被切除而无残留肿瘤,10年后90%的肿瘤复发是主要的治疗挑战。由于新辅助和辅助治疗以及术中放疗未能证明预后价值,因此治疗性切除仍然是原发性和复发性脂肪肉瘤的主要治疗方法。
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引用次数: 2
Coronary Bypass via a Mini-Thoracotomy: Advantages Become Evident with the Growing Experience of the Medical Team 小开胸冠状动脉搭桥术:随着医疗团队经验的增长,优势越来越明显
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.7.1.16
Tevaearai, Mueller, Chastonay, Favre, Ravussin, Eckert, Vogt, Delabays, von Segesser, Stumpe
But du travail: La chirurgie de revascularisation myocardique minimale invasive est fondamentalement differente de la methode classique sous circulation extra-corporelle (CEC). Elle oblige a de nombreuses adaptations tant operatoire, qu'anesthesiologique et post-operatoire. Nous evaluons l'effet eventuel d'une phase d'apprentissage sur les resultats a court terme de cette nouvelle technique. Methode: Nous presentons notre experience de 20 patients ayant beneficies de cette approche de juillet 1997 a fevrier 1999, en comparant du point de vue chirurgical et post-operatoire, 2 collectifs successifs de 10 patients chacun (groupe 1: 8H2F; 59.6 +/- 13.8 ans) aux 10 derniers (groupe 2: 8H/2F; 63.2 +/- 6.1 ans). Discussion: La progression est remarquable du point de vue operatoire et post-operatoire: Le temps de clampage de l'IVA est passe de 28.5 +/- 2.4 min. a 22.2 +/- 1.8 min. (p < 0.05) et le temps operatoire est passe de 125 +/- 4 a 97 +/- 5 min. (p < 0.005). La morbidite post-operatoire a regresse avec un ...
目的:微创心肌血管重建手术与传统的体外循环(ecc)方法有根本的不同。它需要许多手术、麻醉和术后的适应。我们评估学习阶段对这种新技术的短期结果可能产生的影响。方法:从1997年7月到1999年2月,我们展示了20例受益于该方法的患者的经验,从手术和术后的角度比较了2组连续10例患者(组1:8 h2f;组1:8 h2f;组1:8 h2f)。59.6 +/- 13.8年)至最近10年(第二组:8H/2F;63.2 +/- 6.1年)。讨论:是了不起的进步的角度来看,社群和post-operatoire: 28.5 l’IVA clampage是时间流逝的+ / - 2.4 a 22.2分钟+ / - 1.8分钟。(p < 0.05)和社群是时间流逝的+ / - 4 . 97 / 125 - 5 min (p < . 005)。术后发病率又回来了。
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引用次数: 0
The Learning Curve and Clinical Safety of Stapled Haemorrhoidectomy: A Prospective Study of 61 Patients 61例痔钉切除术的学习曲线和临床安全性:一项前瞻性研究
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.8.1.31
Hetzer, Schäfer, Demartines, Clavien
Einleitung: Mit der Stapler-Hamorrhoidektomie (SH) ist ein neues Verfahren zur Behandlung der prolabierenden Hamorrhoiden entwickelt worden. Uber Lernkurve, Komplikationsrate und Langzeitverlauf gibt es bis heute nur wenige Berichte in der Literatur. Wir haben deshalb unsere Patienten prospektiv erfasst und ambulant nachkontrolliert. Methoden: Von Marz 1999 bis Mai 2001 wurde bei 61 Patienten mit Hamorrhoiden II (n = 18), Grad III (n = 38) und Grad IV (n = 5) nach schriftlicher Einwilligung eine SH durchgefuhrt. Operationszeit und perioperative Komplikationen wurden prospektiv erfasst und mit der Erfahrung des Operationsteams korreliert. Anhand der visual analogue scale (VAS) konnte die postoperative Schmerzintensitat gemessen werden. Mittels pra- und postoperativ erhobenen Inkontinenzscore nach Williams und der histologischen Untersuchung des Exzisates wurde nach Sphinkterlasionen gesucht. Ambulante Nachkontrollen erfolgten nach drei Wochen und drei Monaten. Ergebnisse: Operationsdauer und Komplikationsr...
引言:铲掉痔疮疗法(SH)开发了一种新的治疗痔疮的方法。迄今为止,文献中关于学习曲线、并发症率、长期趋势的记载很少。所以我们得告知病人探望伤病的心理医生…方法:从1999年3月至2001年5月,有61位患有痔疮II (n = 18)、氏三度(n = 38)和氏四度(n = 5)的患者在书面同意后通过SH。手术时间和术后并发症分析出来,并与其手术小组的经验相关联。通过模拟效果,病人可以测量术后疼痛。尸检和术后失禁检查表现在威廉斯和驱尸者的史前记录上门诊检查是三周零三个月后进行的。结果:手术时间与并发症
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引用次数: 9
[Intercostal nerve syndrome]. 肋间神经综合征。
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.7.2.82
A. Oesch, K. Küpfer, A. Bodoky
The intercostal nerve syndrome is caused by an impingement of the intercostals nerve at the level of the anterior rectus sheath. It may lead to acute or chronic abdominal pain, it should therefore be considered in the differential diagnosis of the acute or chronic abdomen. A positive Carnett-test and an effective local anaesthesia at the point of maximal tenderness allow the correct diagnosis. In our retrospective study 14 patients with 15 entrapment syndromes are described. If, sometimes after a few diagnostic and therapeutic detours, the diagnosis is established, surgical intervention with resection of the altered nerve at it's exit of the anterior rectus sheath can usually abolish the pain with little side effects.
肋间神经综合征是由肋间神经在前直肌鞘水平的撞击引起的。它可能导致急性或慢性腹痛,因此在急性或慢性腹部的鉴别诊断中应予以考虑。阳性的卡尼特试验和在最大压痛点有效的局部麻醉允许正确的诊断。在我们的回顾性研究中,描述了14例15种夹持综合征的患者。如果,有时经过一些诊断和治疗的迂回,诊断是确定的,手术干预切除改变的神经在前直肌鞘的出口通常可以消除疼痛,几乎没有副作用。
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引用次数: 11
Stress Fracture of the Cuboid Bone: A Rarity which Is Simple to Treat 长方体骨应力性骨折:罕见且治疗简单
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.8.1.3
Battaglia, Simmen, Meier
Stressfrakturen des Os cuboideum sind sehr selten. Meist werden diese Frakturen, wie in unserem vorliegenden Fall, bei ambitionierten Sportlern gesehen. Die geschilderten Symptome sind unspezifisch. Die Anamnese und die klinische Untersuchung, erganzt durch das konventionelle Rontgenbild, sollten einen Verdacht ergeben. Zur Diagnosesicherung konnen Knochenszintigraphie, Computertomogramm oder Magnetresonanz erforderlich werden. Therapeutisch steht die Ruhigstellung im Unterschenkelgehgips oder allenfalls mit konfektionierter Schiene im Vordergrund. Im vorliegenden Fall konnte auf konservativem Wege nach wenigen Wochen die Abheilung erzielt werden. Wichtig ist auch die Anpassung der weiteren sportlichen Aktivitaten, bei Bedarf erganzt durch fussorthopadische Massnahmen wie z.B. die Einlageversorgung, bzw. korrektes Schuhwerk. Besonders in Laufsportarten ist die Bedeutung der optimalen Schuhversorgung zur Behandlung oder Prophylaxe von Uberlastungsproblemen bekannt.
0到100度,腿部骨折一如本文,许多运动员都能看出以上的骨折。故事也写的经不起写肛门探针和临床试验…被传统的缩进图引起人们的怀疑为了进行诊断,可以使用不同的骨锉、电脑断层扫描或磁共振成像。手术的主题是用餐巾纸保持镇静或者适度放糖在这一案例中,几周后伤口得以恢复。此外,为运动活动的后续调整也很重要,必要时会被提供正确的鞋带的功能所取代。特别是在跑步方面,人们知道最佳的鞋护理在治疗或预防肥胖问题上的重要性。
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引用次数: 9
[Distal radius fractures--retrospective quality control after conservative and operative therapy]. [桡骨远端骨折——保守和手术治疗后的回顾性质量控制]。
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.7.2.68
Ch. Sommer, L. Brendebach, R. Meier, A. Leutenegger
BACKGROUNDThe distal radius fracture is the most frequent fracture in the adult patient. The wide spectrum of different types of fracture and the coexisting factors make the choice for the optimal treatment difficult. As an interne quality control we retrospectively evaluated all patients with distal radius fractures treated in 1995 at our institution.METHODSThe study included 69 adult patients with 71 distal radius fractures. After on average 26 months 58 patients with 59 fractures were clinically and radiologically evaluated. The patients were asked to give supplementary information about their follow-up treatment as well as any remaining physical difficulties and limitations in the daily life. All x-rays of the broken radius were carefully analysed and compared with the opposite side. The final results were evaluated according to the "Demerit Point System".RESULTSPatients were treated with five different therapeutical methods. 76.3% of the patients showed a very good/good final result. In 56.7% of the cases secondary fracture dislocation occurred; the dislocation-rate of fractures treated with percutaneous k-wires was 93.3%! A clear correlation between secondary displacement and final results was found.CONCLUSIONA main factor for an optimal outcome is the anatomic restoration of length and axis of the distal radius as well as of joint congruency, also moderate angular deformities are well tolerated. Our collective showed an unexpected high rate of secondary displacement, especially in the k-wire group. The reasons for this unsatisfactory event are manifold: too optimistic indication, insufficient follow-up examination in the first four to six weeks, inconsequent change to a more stable fixation method in case of a secondary dislocation. The results of this retrospective evaluation had a major impact on our concept of treatment. The dorso-radial double-plate technique combined with bone graft will be more used in the future especially in younger patients. The new standardised concept is the base of a present prospective study.
背景:桡骨远端骨折是成人患者中最常见的骨折。不同类型骨折的广谱性和共存的因素使得选择最佳治疗方法变得困难。作为内部质量控制,我们回顾性评估了1995年在我院治疗的所有桡骨远端骨折患者。方法对69例71例桡骨远端骨折的成人患者进行研究。平均26个月后,58例59例骨折患者进行了临床和影像学评估。患者被要求提供关于后续治疗的补充信息,以及日常生活中任何剩余的身体困难和限制。所有骨折桡骨的x光片都被仔细分析,并与另一侧进行了比较。最终成绩根据“扣分制度”进行评定。结果患者采用5种不同的治疗方法。76.3%的患者表现出很好的最终效果。继发性骨折脱位占56.7%;经皮k针治疗骨折脱位率为93.3%!二次位移与最终结果之间存在明显的相关性。结论桡骨远端长度、轴向和关节一致性的解剖恢复是获得最佳治疗效果的主要因素,中度角度畸形也能得到良好的耐受。我们的集体显示出意想不到的高二次位移率,特别是在k线组。造成这种不满意的事件的原因是多方面的:过于乐观的迹象,在最初的4到6周内随访检查不足,在继发性脱位的情况下没有及时更换更稳定的固定方法。这项回顾性评估的结果对我们的治疗理念产生了重大影响。背桡侧双钢板技术结合骨移植将在未来得到更多的应用,特别是在年轻患者中。新的标准化概念是当前前瞻性研究的基础。
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引用次数: 11
Achilles Tendon Rupture After Local Steroid Injection 局部类固醇注射后跟腱断裂
Pub Date : 2013-01-07 DOI: 10.1024/1023-9332.7.4.184
Csizy, Hintermann
Obgleich hinlanglich bekannt ist, dass Steroide das Rupturrisiko von Sehnen erhohen, werden zur Behandlung der Achillodynie lokal infiltrierte Steroide immer noch angewandt. In den drei beschriebenen Fallen zeigt sich ein inadaquater Rupturmechanismus sowie intraoperativ nekrotische Veranderungen der Sehnenstruktur, welche an intakten Sehnen nicht gesehen werden. Alle Patienten werden operativ mit einer Rekonstruktionstechnik versorgt, wobei gesundes, korpereigenes Material zur Uberbruckung von bestehenden Gewebedefekten verwendet wird. Obschon in einem Fall eine relevante lokale Heilungsstorung eintritt, zeigen alle ein Jahr postoperativ gunstige Resultate mit voller Belastbarkeit und Sportfahigkeit.
尽管众所周知类固醇可能导致肌腱脱臼,但当地潜入的类固醇仍然用于治疗肾上腺素。在3个纵横杆中,一个卵巢破裂和视神经组织的坏死畸变,都是未受破坏的部分。所有患者都能借助外科手术复原技术,用健康的纤维材料修补体内的组织缺陷。在某些情况下,当地的治疗测试是很重要的,然而每个人都表现出出一年的后外科手术成绩,都是很有韧性的,还有体育技能测试。
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引用次数: 18
期刊
Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera
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