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Training in infection prevention and control: survey on the volume and on the learning demands of healthcare-associated infections control figures in the Emilia-Romagna Region (Northern Italy). 感染预防与控制培训:关于艾米利亚-罗马涅大区(意大利北部)医疗相关感染控制人数和学习需求的调查。
IF 2 Q2 Medicine Pub Date : 2024-06-20 DOI: 10.7416/ai.2024.2643
Eleonora Ferrari, Patrizia Scannavini, Lucia Palandri, Elisa Fabbri, Grazia Tura, Catia Bedosti, Angela Zanni, Daniela Mosci, Elena Righi, Elena Vecchi

Background: In the context of Infections Prevention and Control activities, the training of healthcare-associated infection control figures is crucial; the COVID-19 pandemic further emphasized the necessity of ensuring a widespread and stable level of skills over time for such professionals. The present work aims to identify the number and training needs of the personnel working in the Emilia-Romagna Region's healthcare facilities as "healthcare-associated infection control figures".

Methods: Data were collected through a survey created by experts from the Regional Group "Training in the prevention and control of antibiotic resistance". The questionnaire explored the number, professional and educational background, and training requirements of Healthcare-associated infections control figures in Emilia-Romagna.

Results: With 73 figures dedicated to Healthcare-associated infections control, the Emilia-Romagna Region appears to be in line with the European standard ratio (1 professional every 125 beds). Professionals with a nursing background, over 50 years old and of female sex prevail in the group, while the training needs expressed include both theoretical and practical aspects.

Conclusions: Healthcare assistants and nursing staff represent a fundamental resource for the implementation of infection prevention and control programs in our healthcare facilities; continuous, multidisciplinary and targeted training of these professionals is confirmed as necessary.

背景:在感染预防和控制活动中,对医疗保健相关感染控制人员的培训至关重要;COVID-19 大流行进一步强调了确保此类专业人员的技能水平长期保持广泛和稳定的必要性。本研究旨在确定在艾米利亚-罗马涅大区医疗机构工作的 "医疗相关感染控制人员 "的数量和培训需求:方法:由 "预防和控制抗生素耐药性培训 "地区小组的专家通过调查收集数据。问卷调查了艾米利亚-罗马涅地区医疗相关感染控制人员的数量、专业和教育背景以及培训要求:结果:艾米利亚-罗马涅大区共有 73 名专门从事医疗相关感染控制的人员,似乎符合欧洲标准比例(每 125 张病床配备 1 名专业人员)。具有护理背景、年龄在 50 岁以上且性别为女性的专业人员在这一群体中占多数,而他们所表达的培训需求包括理论和实践两个方面:结论:医疗助理和护理人员是医疗机构实施感染预防和控制计划的基本资源;对这些专业人员进行持续、多学科和有针对性的培训是必要的。
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引用次数: 0
The prevention of medication errors in the home care setting: a scoping review. 预防家庭护理环境中的用药错误:范围界定综述。
IF 2 Q2 Medicine Pub Date : 2024-05-30 DOI: 10.7416/ai.2024.2641
Sara Dionisi, Noemi Giannetta, Gloria Liquori, Aurora De Leo, Nicolò Panattoni, Mariasole Caiafa, Marco Di Muzio, Emanuele Di Simone

Background: The changes in health, social and demographic needs impose new approaches to cures and care without giving up patients' safety. Although several studies analysed the patient safety approach and strategies, the literature considering the home care setting seems still scarce. The analysis of the phenomenon of medication errors in the primary care setting highlights the necessity of exploring the specific variables to understand how to prevent or reduce the occurrence of a medication error in the home context. This review investigates the main preventive strategies implemented at the patients' home to prevent and/or limit the possibility of a medication error.

Design: The scoping review was conducted under the Preferred Reporting Items for Systematic Reviews and Meta-Analyses ex-tension for Scoping Reviews (PRISMA-ScR) statement and based on the guidelines of the Joanna Briggs Institute.

Methods: No time or language limit was set to obtain the most comprehensive results possible. The following databases were queried: PubMed, Cochrane, CINAHL, ERIC and PsycINFO via EBSCO. All literature published up to 31 December 2022 was considered for data collection.

Results: The main preventive strategies implemented in the patient's home to prevent a medication error are: Multidisciplinary teams, therapeutic reconciliation and computerised systems that improve information sharing. As evidenced by all of the included studies, no educational intervention or preventive strategy individually reduces the risk of making a medication error.

Conclusions: It would be desirable for healthcare professionals to be constantly updated about their knowledge and understand the importance of introducing the aforementioned preventive strategies to guarantee safe care that protects the person from me-dication errors even at the patient's home.

背景:健康、社会和人口需求的变化要求在不放弃患者安全的前提下,采取新的治疗和护理方法。虽然有多项研究分析了患者安全的方法和策略,但考虑到家庭护理环境的文献似乎仍然很少。对初级医疗环境中的用药错误现象进行分析,凸显了探索特定变量以了解如何预防或减少家庭环境中用药错误发生的必要性。本综述调查了在患者家中实施的主要预防策略,以预防和/或限制用药错误发生的可能性:范围界定综述是根据《范围界定综述的系统综述和荟萃分析首选报告项目》(PRISMA-ScR)声明和乔安娜-布里格斯研究所(Joanna Briggs Institute)的指导方针进行的:为了尽可能获得最全面的结果,没有设定时间或语言限制。查询了以下数据库:通过 EBSCO 查询了 PubMed、Cochrane、CINAHL、ERIC 和 PsycINFO。所有截至 2022 年 12 月 31 日发表的文献均被纳入数据收集范围:在患者家中实施的预防用药错误的主要策略有多学科团队、治疗协调和计算机化系统可改善信息共享。所有纳入的研究都表明,没有任何一种教育干预或预防策略能单独降低用药错误的风险:医护人员应不断更新知识,了解采用上述预防策略的重要性,以确保安全护理,保护患者即使在家中也不会发生用药错误。
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引用次数: 0
Prevalence and predictors of hand hygiene compliance in clinical, surgical and intensive care unit wards: results of a second cross sectional study at the Umberto I teaching hospital of Rome. 临床、外科和重症监护病房手部卫生依从性的普遍性和预测因素:罗马翁贝托一世教学医院第二次横断面研究的结果。
IF 2 Q2 Medicine Pub Date : 2024-05-23 DOI: 10.7416/ai.2024.2642
Mariateresa Ceparano, Antonio Covelli, Valentina Baccolini, Claudia Isonne, Antonio Sciurti, Giuseppe Migliara, Maria De Giusti, Carolina Marzuillo, Paolo Villari

Introduction: Hand hygiene is the most cost-effective procedure for the prevention of healthcare-associated infections, but healthcare worker compliance is often insufficient.

Research design: The objective of this second cross-sectional study was to quantify hand hygiene compliance among the healthcare workers of a large teaching hospital, to explore associated factors and to compare results to those of the 2021 study.

Methods: In 2022, educational sessions were conducted within each hospital department during which hospital healthcare workers received tailored feedback on the hand hygiene compliance registered in the previous year. Then, one month later, direct observations hand hygiene compliance with five World Health Organization recommendations were collected again by anonymous observers in each ward. Data were grouped by healthcare area (clinical, surgical and intensive care), and three multivariable logistic regression models were built to identify predictors of hand hygiene compliance.

Result: Overall, 5,426 observations were collected by 73 observers in three weeks. Hand hygiene compliance was 79.7%, 73.5% and 63.1% in clinical, surgical and intensive care areas, respectively, increasing in clinical wards but decreasing in surgical departments compared to the 2021 study. The multivariable analyses showed that hand hygiene compliance after patient contact was consistently higher than before patient contact, while there was some variability in compliance with other factors across the three areas.

Conclusion: The study found suboptimal adherence to good hand hygiene practice, with the lowest rates observed before patient interaction, which, together with the variability recorded across departments, underscores the challenges involved in achieving a uniform level of compliance. Hence, additional training is essential to raise awareness among healthcare workers, while repeating this survey over time will also be crucial, so that hand hygiene compliance can be monitored and any major issue identified.

导言:手部卫生是预防医护人员相关感染的最具成本效益的程序,但医护人员的依从性往往不足:第二次横断面研究的目的是量化一家大型教学医院医护人员的手卫生依从性,探讨相关因素,并将结果与2021年的研究结果进行比较:2022 年,医院在每个科室开展了教育活动,在此期间,医院医护人员收到了关于上一年手卫生依从性的定制反馈。一个月后,匿名观察员在每个病房再次直接观察手部卫生是否符合世界卫生组织的五项建议。数据按医疗区域(临床、外科和重症监护)分组,并建立了三个多变量逻辑回归模型,以确定手部卫生依从性的预测因素:73名观察员在三周内共观察了5426次。与 2021 年的研究相比,临床病房的手卫生依从性有所提高,但外科部门的依从性有所下降。多变量分析表明,接触患者后的手部卫生依从性一直高于接触患者前,而这三个区域在其他因素的依从性方面存在一些差异:研究发现,良好手部卫生习惯的依从性并不理想,与患者接触前的依从性最低,再加上各科室记录的差异,凸显了要达到统一的依从性水平所面临的挑战。因此,必须开展更多培训以提高医护人员的意识,同时在一段时间内重复这项调查也很重要,这样就能监测手部卫生的依从性并找出任何重大问题。
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引用次数: 0
Enhancing Physicians' Autonomy through Practical Trainings. 通过实践培训增强医生的自主性。
IF 2 Q2 Medicine Pub Date : 2024-05-23 DOI: 10.7416/ai.2024.2638
Giuseppe Stirparo, Luca Gambolò, Dario Bottignole, Daniele Solla, Martino Trapani, Giuseppe Ristagno, Fabrizio Pregliasco, Carlo Signorelli

Background: In medical emergencies adherence to standardized clinical protocols is crucial to ensure a better outcome for patients. Newly qualified physicians may play several roles in serving the National Health Service (substituting general practitioners, on-call duty, working in emergency rooms, etc.) in Italy. In these situations, the physician may have to manage critical patients autonomously. Moreover, newly qualified physicians may show a considerable deficiency in routine medical activities. In fact, many universities do not provide a practical simulation training programme, which is why a substantial number of students only face clinical emergencies when they start working after graduation.

Study design: A cross-sectional study was performed by engaging medical doctors. Both experienced physicians and newly licensed physicians (graduated less than 24 months ago) were included in the study.

Methods: A questionnaire was distributed to each participant during SIMED's Courses from June 2021 to December 2022. The questionnaire consisted of two sections. The first one analyzed participation in standardized practical courses on medical emer gencies (Basic Life Support, Advanced Cardiac Life Support, International Trauma Life Support and a course on Advanced Airway Management). The second section analyzed the perceived autonomy of health professionals in the management of five different work settings, using a 5-point likert scale.

Results: 2,168 questionnaires were analyzed, of which 68.7% were from newly qualified doctors and 31.3% from more experienced doctors The highest rate of physicians who undertook training courses was achieved for the basic life support course (77.5%) and the lowest rate for the advanced trauma course (15.9%). Physicians perceive themselves the highest autonomy in Primary Care setting (63.1%), while in the Emergency Department they perceive themselves with less autonomy (24.0%). In the analyzed sample, experienced physicians show a higher percentage of autonomy than newly qualified doctors (31.4% vs 8.1%) in all scenarios.

Conclusions: Our analysis shows a possible correlation between the self-perceived autonomy of physicians and attending practical simulation courses. Although the role of training through practical courses is relevant, the percentage of trained professionals is insufficient and therefore the implementation of practical training projects has to be encouraged.

背景:在医疗紧急情况下,遵守标准化的临床规程对确保患者获得更好的治疗效果至关重要。在意大利,新近获得资格的医生在为国家卫生服务机构服务时可能会扮演多种角色(替代全科医生、值班、在急诊室工作等)。在这些情况下,医生可能需要自主管理危重病人。此外,新获得资格的医生可能在日常医疗活动中表现出相当大的不足。事实上,许多大学并不提供实际模拟培训课程,这就是为什么相当多的学生在毕业后开始工作时才面临临床紧急情况:研究设计:一项横断面研究由医生参与进行。研究对象包括经验丰富的医生和新获得执照的医生(毕业不到 24 个月):在 2021 年 6 月至 2022 年 12 月的 SIMED 课程期间,向每位参与者发放了调查问卷。问卷由两部分组成。第一部分分析了参加医疗急救标准化实践课程(基础生命支持、高级心脏生命支持、国际创伤生命支持和高级气道管理课程)的情况。结果:共分析了 2 168 份调查问卷,其中 68.7% 来自新晋医生,31.3% 来自经验丰富的医生。参加培训课程的医生中,参加基本生命支持课程的比例最高(77.5%),参加高级创伤课程的比例最低(15.9%)。在基层医疗机构,医生认为自己的自主权最大(63.1%),而在急诊科,医生认为自己的自主权较小(24.0%)。在分析的样本中,经验丰富的医生在所有情况下的自主比例都高于新晋医生(31.4% 对 8.1%):我们的分析表明,医生自我感觉的自主性与参加模拟实践课程之间可能存在关联。虽然通过实践课程进行培训的作用是相关的,但受过培训的专业人员比例不足,因此必须鼓励实施实践培训项目。
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引用次数: 0
Mpox: Awareness, knowledge and information channels used by individuals accessing a sexually transmitted infections Helpline. Mpox:使用性传播感染求助热线的个人所使用的认识、知识和信息渠道。
IF 2 Q2 Medicine Pub Date : 2024-05-23 DOI: 10.7416/ai.2024.2637
Pietro Gallo, Norman Galea, Anna Colucci, Rudi Valli, Matteo Schwarz, Emanuele Fanales Belasio, Alfredo d'Ari, Francesca Furiozzi, Anna Caraglia, Rosa Dalla Torre, Anna D'Agostini

Background: Up until recently, monkeypox (mpox) was considered to be a rare zoonotic infection restricted to Central and West Africa. However, in July 2022, the World Health Organization declared mpox to be a public health emergency of international concern, after there were several outbreaks in non-endemic countries. This study assessed the information channels used by individuals accessing the "Telefono Verde AIDS e Infezioni Sessualmente Trasmesse" of Istituto Superiore di Sanità (National Institute of Health in Italy) with regard to mpox. We also evaluated their awareness, and knowledge about mpox focusing on transmission and prevention.

Methods: This is a cross-sectional study conducted on "Telefono Verde AIDS e Infezioni Sessualmente Trasmesse" users, between January and April 2023. The target population was helpline users who were older than 18 years of age, and were phoning the service for the first time (i.e. who have not phoned in the last 12 months). Participants were interviewed using a questionnaire containing 19 questions filled by the interviewer. Collected data were analysed through descriptive statistics, and significance testing.

Results: From January to April 2023, "Telefono Verde AIDS e Infezioni Sessualmente Trasmesse" received 2,389 phone calls, 216 of which participated in this study. Most of these were male (85.2%; n=186), single (79.2%; n=171) and in employment (72.2%; n=156). Awareness about mpox was high (71.3%; n=154), with the central and south/islands regional areas having the highest percentage of participants who heard about the virus (84.3%; n=43 vs 72.4%; n=42; p=0.078). Television was the most frequently mentioned source of information about mpox by participants (63%; n=97; p<0.001). This medium was also the most preferred source of information about mpox (39%; n=60; p=0.109). The majority of participants stated that they did not know what mpox is (67.6%; n=146), and less than half knew that it is preventable (42.4%; n=89). Of those who stated that mpox is a preventable illness, less than half knew about the existence of a vaccine (44.9%; n=40; p<0.001).

Conclusions: This study provides insights into the awareness, knowledge, prevention tools and information channels of individuals who contacted the "Telefono Verde AIDS e Infezioni Sessualmente Trasmesse". Useful indications for defining future information campaigns were obtained.

背景:直到最近,猴痘一直被认为是一种罕见的人畜共患传染病,仅限于非洲中部和西部。然而,2022年7月,在非流行国家爆发了几起猴痘疫情后,世界卫生组织宣布猴痘为国际关注的突发公共卫生事件。本研究评估了使用意大利国家卫生研究院 "Telefono Verde AIDS e Infezioni Sessualmente Trasmesse "的个人所使用的有关天花的信息渠道。我们还评估了他们对水痘的认识和知识,重点是水痘的传播和预防:这是一项横断面研究,研究对象是 2023 年 1 月至 4 月期间的 "Telefono Verde AIDS e Infezioni Sessualmente Trasmesse "用户。目标人群为 18 岁以上、首次拨打求助热线的用户(即在过去 12 个月内未曾拨打过电话的用户)。受访者接受了由访谈者填写的包含 19 个问题的调查问卷。收集到的数据通过描述性统计和显著性检验进行分析:从 2023 年 1 月到 4 月,"Telefono Verde AIDS e Infezioni Sessualmente Trasmesse "共接到 2389 个电话,其中 216 个参与了本研究。其中大部分为男性(85.2%;n=186)、单身(79.2%;n=171)和在职人员(72.2%;n=156)。对水痘的认知度较高(71.3%;n=154),中部和南部/岛屿地区听说过该病毒的参与者比例最高(84.3%;n=43 vs 72.4%;n=42;p=0.078)。电视是参与者最常提及的有关水痘的信息来源(63%;n=97;p=0.078):这项研究有助于深入了解与 "Telefono Verde AIDS e Infezioni Sessualmente Trasmesse "联系的个人的意识、知识、预防工具和信息渠道。这项研究为确定今后的宣传活动提供了有益的参考。
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引用次数: 0
Indoor air pollution: an Italian Knowledge, Attitude and Practice (KAP) study among the general population. 室内空气污染:意大利对普通人群的知识、态度和实践 (KAP) 研究。
IF 2 Q2 Medicine Pub Date : 2024-05-20 DOI: 10.7416/ai.2024.2640
Roberto Venuto, Roberta Pappalardo, Cristina Genovese, Giuseppe Trimarchi, Raffaele Squeri, Giuseppe La Spada, Vincenza La Fauci

Background: Indoor air pollution negatively affects population health and the national health services in terms of socio-economic costs. The presence of indoor pollutants depends a lot on lifestyles.

Study design: The aim of this work is to evaluate knowledge, daily habits and the preventive behaviors in order to contrast the effects on health caused by indoor pollutants.

Methods: The study was conducted through the administration of questionnaires to the population resident in the metropolitan city of Messina (Italy), asking about sociodemographic characteristics, knowledge, daily habits and preventive behaviors.

Results: The questionnaire was filled by 894 subjects (46.8% M; 53.2% F). Regarding knowledge, 66.8% had heard of indoor air pollution and 94.9% knew what the most common indoor pollutants are; regarding daily habits they often aired out the house (91.9% in the morning and 71.4% after cleaning), 24.8% were smokers and 36.7 of them smoked indoors; regarding preventive behaviors, 41.6% chose the cleaning products based on habit and only 32.9% bought plants able to purify environments.

Conclusions: Although the analyzed population had adequate knowledge of indoor air pollution, this did not strongly impact on the adoption of healthy lifestyles. Therefore, it becomes necessary to intervene on a social level with environmental education activities, starting from school age.

背景:室内空气污染在社会经济成本方面对人口健康和国家卫生服务产生了负面影响。室内污染物的存在在很大程度上取决于生活方式:研究设计:这项工作的目的是评估知识、日常习惯和预防行为,以对比室内污染物对健康的影响:研究通过向墨西拿(意大利)大都市的居民发放调查问卷的方式进行,调查内容包括社会人口学特征、知识、日常习惯和预防行为:894名受访者(46.8%为男性;53.2%为女性)填写了问卷。在知识方面,66.8%的人听说过室内空气污染,94.9%的人知道最常见的室内污染物是什么;在日常习惯方面,他们经常在屋内通风(91.9%的人在早上,71.4%的人在打扫后),24.8%的人吸烟,其中36.7%的人在室内吸烟;在预防行为方面,41.6%的人根据习惯选择清洁产品,只有32.9%的人购买能够净化环境的植物:尽管被分析人群对室内空气污染有足够的了解,但这并没有对他们采取健康的生活方式产生很大影响。因此,有必要从学龄儿童开始,在社会层面开展环境教育活动。
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引用次数: 0
A survey on hydration and use of plastic water bottles among Italian health sector workers. 关于意大利卫生部门工作人员补充水分和使用塑料水瓶情况的调查。
IF 2 Q2 Medicine Pub Date : 2024-05-13 DOI: 10.7416/ai.2024.2639
Camilla Lugli, Lucia Palandri, Simona Pedretti, Romana Bacchi, Daniela Altariva, Giulia Guerzoni, Alessia Sala, Claudia Vaccari, Tommaso Filippini, Elena Righi, Marco Vinceti, Gabriele Romani

Background: Modena's Local Health Authority (AUSL) is a public service with more than 5,000 employees. In its facilities, drinking water is available as tap water. However, disposable plastic bottles are also widely used, thus increasing plastic waste.

Study design and methods: In the present study, we aimed to investigate employees' drinking habits through an ad hoc 10-item online questionnaire, which was administered in spring 2023.

Results: Of the 584 participants (10.8% response rate), 75% of workers reported drinking less than 1.5 liters of water per day. In addition, 74% of workers brought water from home, while 62% used disposable plastic containers bought in the workplace or outside. When asked if they would appreciate a water refilling station in the workplace, whether that would induce them to consume less plastic and to drink more water, 91%, 82%, and 72% of workers said "yes", respectively. By installing water coolers, the estimated mean number of plastic bottles spared every day at the AUSL would be about 6,000.

Conclusions: Our data shed light on most employees' perceived need for alternative sources of drinking water, not only in order to drink more for health benefits, but also to reduce plastic usage in favor of reusable, more environmentally friendly materials.

背景介绍摩德纳地方卫生局 (AUSL) 是一家拥有 5000 多名员工的公共服务机构。在其设施中,饮用水为自来水。然而,一次性塑料瓶也被广泛使用,从而增加了塑料垃圾:在本研究中,我们于 2023 年春季通过一份特设的 10 个项目的在线问卷调查了员工的饮水习惯:结果:在 584 名参与者(回复率为 10.8%)中,75% 的工人表示每天的饮水量不足 1.5 升。此外,74% 的工人从家里带水,62% 的工人使用在工作场所或室外购买的一次性塑料容器。当被问及是否希望在工作场所设置加水站,是否会促使他们减少使用塑料制品和多喝水时,分别有 91%、82% 和 72% 的工人表示 "是"。通过安装饮水机,估计澳大拉德芳斯每天平均可减少约 6000 个塑料瓶:我们的数据揭示了大多数员工对替代性饮用水源的需求,这不仅是为了多喝水有益健康,也是为了减少塑料瓶的使用,使用可重复使用的、更环保的材料。
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引用次数: 0
Management of a Neisseria meningitidis case: factors that guarantee the effectiveness of supporting Public Health actions. 脑膜炎奈瑟菌病例的管理:保证公共卫生支持行动有效性的因素。
IF 2 Q2 Medicine Pub Date : 2024-05-02 DOI: 10.7416/ai.2024.2634
Anna Voltolini, Vincenzo Marcotrigiano, Serena Cian, Nahuel Fiorito, Alfonsina Sollano, Ilaria Dall'O, Marica Battistin, Erica Bino, Alberto Lovat, Pamela D'Incà, Tatjana Baldovin, Vincenzo Baldo, Sandro Cinquetti

Abstract: Among invasive bacterial diseases, meningococcal meningitis is a serious and contagious disease caused by Neisseria meningitidis. The disease has a high lethality grade and could have long-term sequelae. This paper describes a case of meningitis that occurred in the territory under the jurisdiction of Local Health Authority ULSS 1 Dolomiti and the related management methods. The activities described concern rapid alerts, an epidemiological investigation, the administration of chemoprophylaxis and offering vaccinations, implemented according to the current Public Health protocol through different healthcare workers. This case report aims to support the management of possible similar cases, underlining the conditions that favoured the application of the envisaged measures, including an on-call ready availability service; the presence of population vaccination centres located in the area investigated; and a network sensitive to early warnings and collaboration within and between Local Health Authorities.

摘要:在侵袭性细菌疾病中,脑膜炎球菌性脑膜炎是由脑膜炎奈瑟菌引起的一种严重的传染性疾病。该病致死率很高,并可能产生长期后遗症。本文介绍了发生在多洛米蒂第 1 多洛米蒂地方卫生局(ULSS 1 Dolomiti)辖区内的一例脑膜炎病例以及相关的管理方法。所描述的活动涉及快速预警、流行病学调查、实施化学预防和提供疫苗接种,这些都是根据当前的公共卫生协议通过不同的医护人员实施的。本病例报告旨在支持对可能发生的类似病例的管理,强调了有利于实施所设想措施的条件,包括随叫随到的随时可用服务、位于调查地区的人口疫苗接种中心、对预警敏感的网络以及地方卫生当局内部和之间的合作。
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引用次数: 0
Anti-rubella seroprevalence assessment in an adult sample population in Italy. 意大利成人样本人群抗风疹血清流行率评估。
IF 2 Q2 Medicine Pub Date : 2024-05-02 DOI: 10.7416/ai.2024.2632
Angela Bechini, Beatrice Zanella, Benedetta Bonito, Marta Betti, Enrica Stancanelli, Marco Del Riccio, Cristina Salvati, Paolo Bonanni, Jacopo Bianchi, Ilaria Biondi, Martina Chellini, Maddalena Innocenti, Federico Manzi, Diana Paolini, Gino Sartor, Lorenzo Baggiani, Simonetta Baretti, Monica Della Fonte, Giorgio Garofalo, Giovanna Mereu, Maria Grazia Santini, Sara Boccalini

Introduction: Despite global immunization efforts, rubella remains a public health concern, particularly in high- and middle-income countries. This study focused on rubella seroprevalence in the province of Florence, Italy, aiming to identify susceptibility clusters, especially among women in their childbearing age.

Methods: A cross-sectional study was conducted between April 2018 and December 2019, enrolling 430 adult subjects (age over 18 years). Serum samples were collected, and anti-rubella antibodies were quantified using the ELISA test. Data were analyzed descriptively and compared by sex, nationality, and age groups using statistical tests.

Results: The overall rubella seroprevalence was high (92.3%), with no significant differences between genders or nationalities. Among childbearing-age females (18-49 years), the highest seroprevalence was observed in the 30-39 age group (94.1%). However, susceptibility clusters exceeding the 5% threshold set by WHO were identified, especially in females aged 40-49 years (7.0%).

Conclusions: Despite high overall seroprevalence, the study identified pockets of susceptibility, even in childbearing age women. Continuous monitoring, targeted immunization strategies, and public health interventions are recommended to maintain rubella elimination, emphasizing the importance of sustained vaccination efforts to protect vulnerable populations.

导言:尽管全球都在努力接种风疹疫苗,但风疹仍然是一个公共卫生问题,尤其是在中高收入国家。本研究重点关注意大利佛罗伦萨省的风疹血清流行情况,旨在确定易感人群,尤其是育龄妇女:2018年4月至2019年12月期间进行了一项横断面研究,共招募了430名成年受试者(18岁以上)。收集血清样本,并使用 ELISA 试验对抗风疹抗体进行量化。对数据进行了描述性分析,并通过统计检验对不同性别、国籍和年龄组的数据进行了比较:结果:风疹血清阳性率总体较高(92.3%),性别和国籍之间无明显差异。在育龄女性(18-49 岁)中,30-39 岁年龄组的血清阳性率最高(94.1%)。然而,在40-49岁女性(7.0%)中也发现了超过世界卫生组织规定的5%阈值的易感人群:结论:尽管总体血清流行率较高,但该研究发现了易感人群,甚至在育龄妇女中也存在易感人群。建议通过持续监测、有针对性的免疫战略和公共卫生干预措施来保持风疹的消除,同时强调持续接种疫苗以保护易感人群的重要性。
{"title":"Anti-rubella seroprevalence assessment in an adult sample population in Italy.","authors":"Angela Bechini, Beatrice Zanella, Benedetta Bonito, Marta Betti, Enrica Stancanelli, Marco Del Riccio, Cristina Salvati, Paolo Bonanni, Jacopo Bianchi, Ilaria Biondi, Martina Chellini, Maddalena Innocenti, Federico Manzi, Diana Paolini, Gino Sartor, Lorenzo Baggiani, Simonetta Baretti, Monica Della Fonte, Giorgio Garofalo, Giovanna Mereu, Maria Grazia Santini, Sara Boccalini","doi":"10.7416/ai.2024.2632","DOIUrl":"https://doi.org/10.7416/ai.2024.2632","url":null,"abstract":"<p><strong>Introduction: </strong>Despite global immunization efforts, rubella remains a public health concern, particularly in high- and middle-income countries. This study focused on rubella seroprevalence in the province of Florence, Italy, aiming to identify susceptibility clusters, especially among women in their childbearing age.</p><p><strong>Methods: </strong>A cross-sectional study was conducted between April 2018 and December 2019, enrolling 430 adult subjects (age over 18 years). Serum samples were collected, and anti-rubella antibodies were quantified using the ELISA test. Data were analyzed descriptively and compared by sex, nationality, and age groups using statistical tests.</p><p><strong>Results: </strong>The overall rubella seroprevalence was high (92.3%), with no significant differences between genders or nationalities. Among childbearing-age females (18-49 years), the highest seroprevalence was observed in the 30-39 age group (94.1%). However, susceptibility clusters exceeding the 5% threshold set by WHO were identified, especially in females aged 40-49 years (7.0%).</p><p><strong>Conclusions: </strong>Despite high overall seroprevalence, the study identified pockets of susceptibility, even in childbearing age women. Continuous monitoring, targeted immunization strategies, and public health interventions are recommended to maintain rubella elimination, emphasizing the importance of sustained vaccination efforts to protect vulnerable populations.</p>","PeriodicalId":7999,"journal":{"name":"Annali di igiene : medicina preventiva e di comunita","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Japanese Encephalitis can be devastating. 日本脑炎可能具有毁灭性。
IF 2 Q2 Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-01 DOI: 10.7416/ai.2024.2616
Pier Luigi Lopalco, Luigi Roberto Biasio

Abstract: Japanese encephalitis, caused by the JE virus transmitted by mosquitoes, is the most common type of epidemic encephalitis in Asia. It is endemic in most of South and Southeast Asia, but the number of cases can vary greatly between areas. While many infections do not lead to disease, the symptomatic cases can be very severe and life-threatening. It mainly affects children, whereas adults are generally immune to the disease due to either being infected in childhood or receiving vaccination. However, individuals who are not immune, such as travelers from non-endemic countries, are susceptible to the disease when exposed to the virus for the first time, regardless of age. Without antiviral treatment options, vaccination is the only strategy to establish effective protection against Japanese encephalitis.

摘要:由蚊子传播的日本脑炎病毒引起的日本脑炎是亚洲最常见的流行性脑炎类型。它在南亚和东南亚的大部分地区流行,但不同地区的病例数量可能相差很大。虽然许多感染不会导致疾病,但有症状的病例可能非常严重并危及生命。这种疾病主要影响儿童,而成年人由于在童年时受到感染或接种过疫苗,一般对这种疾病有免疫力。然而,没有免疫力的人,如来自非流行国家的旅行者,在首次接触病毒时,无论年龄大小,都很容易感染这种疾病。在没有抗病毒治疗方案的情况下,接种疫苗是有效预防日本脑炎的唯一策略。
{"title":"Japanese Encephalitis can be devastating.","authors":"Pier Luigi Lopalco, Luigi Roberto Biasio","doi":"10.7416/ai.2024.2616","DOIUrl":"10.7416/ai.2024.2616","url":null,"abstract":"<p><strong>Abstract: </strong>Japanese encephalitis, caused by the JE virus transmitted by mosquitoes, is the most common type of epidemic encephalitis in Asia. It is endemic in most of South and Southeast Asia, but the number of cases can vary greatly between areas. While many infections do not lead to disease, the symptomatic cases can be very severe and life-threatening. It mainly affects children, whereas adults are generally immune to the disease due to either being infected in childhood or receiving vaccination. However, individuals who are not immune, such as travelers from non-endemic countries, are susceptible to the disease when exposed to the virus for the first time, regardless of age. Without antiviral treatment options, vaccination is the only strategy to establish effective protection against Japanese encephalitis.</p>","PeriodicalId":7999,"journal":{"name":"Annali di igiene : medicina preventiva e di comunita","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140020792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Annali di igiene : medicina preventiva e di comunita
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