首页 > 最新文献

Annals of Medicine and Surgery最新文献

英文 中文
The unforeseen consequence of smart bio-implants for hemophilia: chronic inflammation and antibody development. 智能生物植入血友病的不可预见的后果:慢性炎症和抗体的发展。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004721
Fatima Zohra Ali, Muhammad Shahmeer Khan, Aiman Tahir, Eashaal Imtiaz, Raghabendra Kumar Mahato
{"title":"The unforeseen consequence of smart bio-implants for hemophilia: chronic inflammation and antibody development.","authors":"Fatima Zohra Ali, Muhammad Shahmeer Khan, Aiman Tahir, Eashaal Imtiaz, Raghabendra Kumar Mahato","doi":"10.1097/MS9.0000000000004721","DOIUrl":"10.1097/MS9.0000000000004721","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"2210-2211"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does SGLT2 inhibition modify the inflammatory profile in non-diabetic CKD patients? A new avenue beyond diabetes. SGLT2抑制是否能改变非糖尿病性CKD患者的炎症谱?一条超越糖尿病的新途径。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004672
Muddassir Khalid, Muhammad Abu Bakar, Muhammad Rizwan Javed, Rabia Narmeen Numani
{"title":"Does SGLT2 inhibition modify the inflammatory profile in non-diabetic CKD patients? A new avenue beyond diabetes.","authors":"Muddassir Khalid, Muhammad Abu Bakar, Muhammad Rizwan Javed, Rabia Narmeen Numani","doi":"10.1097/MS9.0000000000004672","DOIUrl":"10.1097/MS9.0000000000004672","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"2186-2187"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone-O2 bio-adhesive: redefining the future of fracture fixation. 骨氧生物胶粘剂:重新定义骨折固定的未来。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004766
Minal Fatima, Hamdia Gul Aslam, Hamza Sajid, Raghabendra Kumar Mahato
{"title":"Bone-O<sub>2</sub> bio-adhesive: redefining the future of fracture fixation.","authors":"Minal Fatima, Hamdia Gul Aslam, Hamza Sajid, Raghabendra Kumar Mahato","doi":"10.1097/MS9.0000000000004766","DOIUrl":"10.1097/MS9.0000000000004766","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"2226-2227"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haptic-feedback robotics in transcervical fetal endoscopy: reducing uterine irritability and the risk of preterm labor. 触觉反馈机器人在经宫颈胎儿内窥镜检查:减少子宫易怒和早产的风险。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004701
Ashbala Usman, Mahnoor Javed, Raghabendra Kumar Mahato, Eashaal Imtiaz, Aiman Tahir
{"title":"Haptic-feedback robotics in transcervical fetal endoscopy: reducing uterine irritability and the risk of preterm labor.","authors":"Ashbala Usman, Mahnoor Javed, Raghabendra Kumar Mahato, Eashaal Imtiaz, Aiman Tahir","doi":"10.1097/MS9.0000000000004701","DOIUrl":"10.1097/MS9.0000000000004701","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"2200-2201"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immediate postpartum family planning utilization and associated factors among postpartum mothers in South Ethiopia. 南埃塞俄比亚产后母亲的产后立即计划生育利用及其相关因素
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004753
Mulugeta E Shate, Robel Mesfin

Introduction: Approximately one-third of maternal deaths worldwide are attributed to unsafe contraceptive practices, a major contributor to maternal mortality. In Ethiopia, immediate postpartum family planning services are not yet widely used. Only 9% of postpartum women use immediate postpartum family planning. Additionally, there was insufficient information regarding the utilization of immediate postpartum family planning in the study area.

Objective: The objective was to assess immediate postpartum family planning utilization and associated factors among mothers attending childbirth at a tertiary hospital in Ethiopia.

Methods: A facility-based cross-sectional study was employed among 402 postpartum women from 1 June to 30 July 2023, using a systematic random sampling technique. Training was provided to data collectors, and data were collected using a structured questionnaire that had been pretested and revised as necessary. The collected data were entered into EpiData 4.6. The data were exported into the software SPSS Version 26 for data cleaning and further analysis. Factors associated with the utilization of immediate postpartum family planning were declared by odds by 95% CI and P < 0.05.

Result: This study involved 393 postpartum mothers, yielding a response rate of 97.76%. As identified from this study, utilization of immediate postpartum family planning was 24.9% (95% CI: 20.6, 29.2) in the study area. Planned pregnancy [adjusted odds ratio (AOR) = 1.84, 95% CI: 1.10-3.13], Postpartum mothers who had five and above children (AOR = 4.68, 95% CI: 1.70-12.88), counseled about family planning before delivery (AOR = 1.78, 95% CI: 1.03-3.10), and intention of postpartum mothers to space their pregnancy (AOR = 3.77, 95% CI: 1.50-9.52) identified associated factors.

Conclusion and recommendation: The utilization of immediate post-partum family planning is low in the study area. Planned pregnancy, the greater number of children, prior information about family planning, and intention to space births during reproductive age were factors significantly associated with the utilization of family planning. Health workers should provide strengthening advice and counseling about family planning, from antenatal care follow-up to the postpartum period. Furthermore, the collaboration of health extension workers provides awareness for the community.

导言:全世界约三分之一的孕产妇死亡归因于不安全的避孕做法,这是孕产妇死亡的一个主要原因。在埃塞俄比亚,产后立即计划生育服务尚未广泛使用。只有9%的产后妇女立即实施产后计划生育。此外,在研究地区,关于产后立即计划生育的使用信息不足。目的:目的是评估在埃塞俄比亚一家三级医院分娩的母亲在产后立即实施计划生育的情况及其相关因素。方法:采用系统随机抽样方法,对2023年6月1日至7月30日402名产后妇女进行横断面研究。向数据收集人员提供了培训,并使用预先测试和必要时修订的结构化问卷收集数据。将收集到的数据输入EpiData 4.6。将数据导出到SPSS Version 26软件中进行数据清洗和进一步分析。产后立即计划生育相关因素的比值为95% CI, P < 0.05。结果:本研究共涉及393名产后母亲,有效率为97.76%。从本研究中发现,在研究区域,立即产后计划生育的利用率为24.9% (95% CI: 20.6, 29.2)。计划妊娠[调整优势比(AOR) = 1.84, 95% CI: 1.10-3.13],产后有5个及以上孩子的母亲(AOR = 4.68, 95% CI: 1.70-12.88),产前接受计划生育咨询(AOR = 1.78, 95% CI: 1.03-3.10),以及产后母亲有意间隔怀孕(AOR = 3.77, 95% CI: 1.50-9.52)确定了相关因素。结论与建议:研究区产后立即计划生育的使用率较低。计划怀孕、子女数目较多、事先了解计划生育的情况以及打算在育龄期间间隔生育是与计划生育的利用显著相关的因素。卫生工作者应加强对计划生育的建议和咨询,从产前保健随访到产后随访。此外,卫生推广工作者的合作提高了社区的认识。
{"title":"Immediate postpartum family planning utilization and associated factors among postpartum mothers in South Ethiopia.","authors":"Mulugeta E Shate, Robel Mesfin","doi":"10.1097/MS9.0000000000004753","DOIUrl":"10.1097/MS9.0000000000004753","url":null,"abstract":"<p><strong>Introduction: </strong>Approximately one-third of maternal deaths worldwide are attributed to unsafe contraceptive practices, a major contributor to maternal mortality. In Ethiopia, immediate postpartum family planning services are not yet widely used. Only 9% of postpartum women use immediate postpartum family planning. Additionally, there was insufficient information regarding the utilization of immediate postpartum family planning in the study area.</p><p><strong>Objective: </strong>The objective was to assess immediate postpartum family planning utilization and associated factors among mothers attending childbirth at a tertiary hospital in Ethiopia.</p><p><strong>Methods: </strong>A facility-based cross-sectional study was employed among 402 postpartum women from 1 June to 30 July 2023, using a systematic random sampling technique. Training was provided to data collectors, and data were collected using a structured questionnaire that had been pretested and revised as necessary. The collected data were entered into EpiData 4.6. The data were exported into the software SPSS Version 26 for data cleaning and further analysis. Factors associated with the utilization of immediate postpartum family planning were declared by odds by 95% CI and <i>P</i> < 0.05.</p><p><strong>Result: </strong>This study involved 393 postpartum mothers, yielding a response rate of 97.76%. As identified from this study, utilization of immediate postpartum family planning was 24.9% (95% CI: 20.6, 29.2) in the study area. Planned pregnancy [adjusted odds ratio (AOR) = 1.84, 95% CI: 1.10-3.13], Postpartum mothers who had five and above children (AOR = 4.68, 95% CI: 1.70-12.88), counseled about family planning before delivery (AOR = 1.78, 95% CI: 1.03-3.10), and intention of postpartum mothers to space their pregnancy (AOR = 3.77, 95% CI: 1.50-9.52) identified associated factors.</p><p><strong>Conclusion and recommendation: </strong>The utilization of immediate post-partum family planning is low in the study area. Planned pregnancy, the greater number of children, prior information about family planning, and intention to space births during reproductive age were factors significantly associated with the utilization of family planning. Health workers should provide strengthening advice and counseling about family planning, from antenatal care follow-up to the postpartum period. Furthermore, the collaboration of health extension workers provides awareness for the community.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"1346-1351"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AI in endodontics: enhancing precision, efficiency, and personalized care. 人工智能在牙髓学中的应用:提高精度、效率和个性化护理。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004385
Omer Abdullah, Marhaba Saleem, Zunaira Hussain, Hamza Mukhtiar, Khushi Ochani, Sidhant Ochani, Kaleem Ullah, Md Asaduzzaman Nur

Artificial Intelligence (AI) is shifting oral health care from a hardware-centric to a software-centric approach, with the potential to solve problems similarly to humans. It is transforming endodontics by enhancing diagnostic accuracy, improving treatment planning, increasing clinical efficiency, and supporting personalized care. This review explores AI applications in endodontics, including working length determination, periapical and caries detection, complex root anatomy segmentation, vertical root fracture identification, and surgical planning. AI models such as convolutional neural networks and artificial neural networks demonstrate high accuracy in interpreting cone-beam computed tomography and radiographic data. Benefits include improved workflow efficiency, reduced misdiagnoses, and individualized treatment strategies. However, challenges persist, such as limited high-quality datasets, regulatory gaps, and ethical considerations. Future directions emphasize technological advancements, collaborative AI-clinician integration, and AI-driven education and training tools. AI stands as a transformative force in endodontics, requiring responsible implementation and continued research to optimize its impact on patient care and clinical practice.

人工智能(AI)正在将口腔卫生保健从以硬件为中心转变为以软件为中心的方法,有可能解决类似于人类的问题。它正在通过提高诊断准确性、改善治疗计划、提高临床效率和支持个性化护理来改变牙髓学。本文综述了人工智能在牙髓学中的应用,包括工作长度确定、根尖周和龋齿检测、复杂根解剖分割、垂直根断裂识别和手术计划。卷积神经网络和人工神经网络等人工智能模型在解释锥束计算机断层扫描和放射成像数据方面表现出很高的准确性。其好处包括提高工作流程效率,减少误诊和个性化治疗策略。然而,挑战依然存在,例如有限的高质量数据集、监管缺口和伦理考虑。未来的发展方向强调技术进步、人工智能与临床医生的协同整合以及人工智能驱动的教育和培训工具。人工智能是牙髓学的变革力量,需要负责任的实施和持续的研究,以优化其对患者护理和临床实践的影响。
{"title":"AI in endodontics: enhancing precision, efficiency, and personalized care.","authors":"Omer Abdullah, Marhaba Saleem, Zunaira Hussain, Hamza Mukhtiar, Khushi Ochani, Sidhant Ochani, Kaleem Ullah, Md Asaduzzaman Nur","doi":"10.1097/MS9.0000000000004385","DOIUrl":"10.1097/MS9.0000000000004385","url":null,"abstract":"<p><p>Artificial Intelligence (AI) is shifting oral health care from a hardware-centric to a software-centric approach, with the potential to solve problems similarly to humans. It is transforming endodontics by enhancing diagnostic accuracy, improving treatment planning, increasing clinical efficiency, and supporting personalized care. This review explores AI applications in endodontics, including working length determination, periapical and caries detection, complex root anatomy segmentation, vertical root fracture identification, and surgical planning. AI models such as convolutional neural networks and artificial neural networks demonstrate high accuracy in interpreting cone-beam computed tomography and radiographic data. Benefits include improved workflow efficiency, reduced misdiagnoses, and individualized treatment strategies. However, challenges persist, such as limited high-quality datasets, regulatory gaps, and ethical considerations. Future directions emphasize technological advancements, collaborative AI-clinician integration, and AI-driven education and training tools. AI stands as a transformative force in endodontics, requiring responsible implementation and continued research to optimize its impact on patient care and clinical practice.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"2091-2095"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapidly enlarging dermatofibrosarcoma protuberans: a case report of atypical presentation with diagnostic complexities and reconstructive challenges. 快速扩大的皮肤纤维肉瘤隆突:一个不典型的报告,诊断的复杂性和重建的挑战。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004682
Syeda Rabiah Shahid, Maliha Khalid, Aminath Waafira

Introduction and importance: Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade dermal sarcoma known for local aggressiveness and high recurrence despite low metastatic potential. Early diagnosis and complete surgical excision with negative margins are critical for management. Reconstruction can be challenging, especially for large lesions. We report a rare case of rapidly enlarging DFSP over the lower chest-epigastric junction, complicated by diagnostic delays and complex reconstruction.

Case presentation: A 45-year-old man presented with a 4-5-month history of progressive midline chest swelling, low-grade fever, discomfort, and weight loss. Imaging revealed a vascular subcutaneous mass abutting the sternum. Fine needle aspiration cytology (FNAC) and biopsy remained inconclusive, delaying definitive diagnosis. Wide local excision with 3 cm margins created a 19 × 21 cm midline defect, requiring further extension based on frozen section. Reconstruction utilized a right paraumbilical perforator-based fasciocutaneous flap for primary closure. Final histopathology confirmed DFSP with clear margins and no high-grade transformation. Postoperative recovery was uneventful.

Clinical discussion: This case posed diagnostic and surgical challenges due to atypical presentation over the midline anterior abdominal wall, rapid enlargement of an otherwise indolent lesion, and inconclusive workup. Intraoperatively, the lesion's vascularity and ill-defined margins prolonged surgery with significant blood loss. Multidisciplinary collaboration and intraoperative flexibility remained critical for achieving optimal oncologic and reconstructive outcomes.

Conclusion: Early diagnosis, multidisciplinary planning, and tailored reconstructive strategies are vital in managing extensive, anatomically complex DFSP. This case highlights the importance of diagnosing rare presentations earlier with individualized, lesion-specific surgical approaches in achieving both functional and oncologic success.

简介及重要性:隆突性皮肤纤维肉瘤(DFSP)是一种罕见的低级别皮肤肉瘤,以局部侵袭性和高复发率而闻名,尽管转移潜力低。早期诊断和完全手术切除阴性切缘是治疗的关键。重建是具有挑战性的,特别是对于大的病变。我们报告一个罕见的病例迅速扩大DFSP在胸腹交界处,复杂的诊断延迟和复杂的重建。病例介绍:45岁男性,4-5个月进行性胸中线肿胀、低烧、不适和体重减轻。影像学显示胸骨附近有一个皮下血管性肿块。细针穿刺细胞学(FNAC)和活检仍不确定,延误了最终诊断。宽局部切除3cm边缘造成19 × 21 cm中线缺损,需要在冰冻切片的基础上进一步扩大。重建采用右脐旁穿支筋膜皮瓣进行初步闭合。最终组织病理学证实为DFSP,边缘清晰,无高级别转化。术后恢复顺利。临床讨论:该病例由于前腹壁中线的非典型表现、病变迅速扩大和不确定的检查,对诊断和手术提出了挑战。术中,病变的血管分布和边缘不清延长了手术时间并伴有大量失血。多学科合作和术中灵活性仍然是实现最佳肿瘤和重建结果的关键。结论:早期诊断、多学科规划和量身定制的重建策略对于治疗广泛、解剖复杂的DFSP至关重要。本病例强调了早期诊断罕见表现的重要性,采用个性化的、病变特异性的手术方法,以实现功能和肿瘤的成功。
{"title":"Rapidly enlarging dermatofibrosarcoma protuberans: a case report of atypical presentation with diagnostic complexities and reconstructive challenges.","authors":"Syeda Rabiah Shahid, Maliha Khalid, Aminath Waafira","doi":"10.1097/MS9.0000000000004682","DOIUrl":"10.1097/MS9.0000000000004682","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade dermal sarcoma known for local aggressiveness and high recurrence despite low metastatic potential. Early diagnosis and complete surgical excision with negative margins are critical for management. Reconstruction can be challenging, especially for large lesions. We report a rare case of rapidly enlarging DFSP over the lower chest-epigastric junction, complicated by diagnostic delays and complex reconstruction.</p><p><strong>Case presentation: </strong>A 45-year-old man presented with a 4-5-month history of progressive midline chest swelling, low-grade fever, discomfort, and weight loss. Imaging revealed a vascular subcutaneous mass abutting the sternum. Fine needle aspiration cytology (FNAC) and biopsy remained inconclusive, delaying definitive diagnosis. Wide local excision with 3 cm margins created a 19 × 21 cm midline defect, requiring further extension based on frozen section. Reconstruction utilized a right paraumbilical perforator-based fasciocutaneous flap for primary closure. Final histopathology confirmed DFSP with clear margins and no high-grade transformation. Postoperative recovery was uneventful.</p><p><strong>Clinical discussion: </strong>This case posed diagnostic and surgical challenges due to atypical presentation over the midline anterior abdominal wall, rapid enlargement of an otherwise indolent lesion, and inconclusive workup. Intraoperatively, the lesion's vascularity and ill-defined margins prolonged surgery with significant blood loss. Multidisciplinary collaboration and intraoperative flexibility remained critical for achieving optimal oncologic and reconstructive outcomes.</p><p><strong>Conclusion: </strong>Early diagnosis, multidisciplinary planning, and tailored reconstructive strategies are vital in managing extensive, anatomically complex DFSP. This case highlights the importance of diagnosing rare presentations earlier with individualized, lesion-specific surgical approaches in achieving both functional and oncologic success.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"2001-2008"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring advancements in the management of penile cancer in the era of artificial intelligence and machine learning: a narrative review. 探索人工智能和机器学习时代阴茎癌管理的进展:叙述性回顾。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004757
Rao Nouman Ali, Sohaib Irfan, Adeel Anwaar, Muhammad Shahzad Anwar, Inam Ul Haq, Muhammad Irfan, Muhammad Shafi Ghouri, Wajiha Irfan, Aymar Akilimali

Purpose of review: This review aims to explore the current state of literature on the use of artificial intelligence (AI) in the management of penile cancer. We examined the various applications of AI in penile cancer, including but not limited to image identification, prediction of treatment results, and patient risk stratification. The review evaluates the current limitations and challenges faced in the implementation of AI in penile cancer management.

Recent findings: The present literature emphasized the use of AI using radiomics and pathomics for management strategies and outcomes.

Summary: AI has the power to shape the future of penile cancer management by improving diagnostic precision, treatment strategies, and patient outcomes. Literature has shown improved accuracy and quality of current AI models for the detection and treatment of penile cancer. Further research is required to understand its potential and limitations.

综述目的:本综述旨在探讨人工智能(AI)在阴茎癌治疗中的应用现状。我们研究了人工智能在阴茎癌中的各种应用,包括但不限于图像识别、治疗结果预测和患者风险分层。这篇综述评估了目前人工智能在阴茎癌管理中实施的局限性和面临的挑战。最近的发现:目前的文献强调人工智能使用放射组学和病理学的管理策略和结果。摘要:人工智能有能力通过提高诊断精度、治疗策略和患者预后来塑造阴茎癌管理的未来。文献表明,目前用于阴茎癌检测和治疗的人工智能模型的准确性和质量有所提高。需要进一步的研究来了解它的潜力和局限性。
{"title":"Exploring advancements in the management of penile cancer in the era of artificial intelligence and machine learning: a narrative review.","authors":"Rao Nouman Ali, Sohaib Irfan, Adeel Anwaar, Muhammad Shahzad Anwar, Inam Ul Haq, Muhammad Irfan, Muhammad Shafi Ghouri, Wajiha Irfan, Aymar Akilimali","doi":"10.1097/MS9.0000000000004757","DOIUrl":"10.1097/MS9.0000000000004757","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to explore the current state of literature on the use of artificial intelligence (AI) in the management of penile cancer. We examined the various applications of AI in penile cancer, including but not limited to image identification, prediction of treatment results, and patient risk stratification. The review evaluates the current limitations and challenges faced in the implementation of AI in penile cancer management.</p><p><strong>Recent findings: </strong>The present literature emphasized the use of AI using radiomics and pathomics for management strategies and outcomes.</p><p><strong>Summary: </strong>AI has the power to shape the future of penile cancer management by improving diagnostic precision, treatment strategies, and patient outcomes. Literature has shown improved accuracy and quality of current AI models for the detection and treatment of penile cancer. Further research is required to understand its potential and limitations.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"2230-2235"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergency cricothyrotomy in five in-hospital "cannot intubate, cannot oxygenate" cases: a case series. 急诊环甲环切开术治疗5例院内“不能插管,不能充氧”病例:病例系列。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004680
Munehiro Yoshitomi, Syuichirou Sagara, Yuuji Tokuda, Tomohiro Inoue, Yoshikuni Koutaki, Naoyuki Tokuyama, Takaaki Mabe, Aoi Ichikawa, Syunsuke Hisaka, Naoto Chuman, Miki Yamamoto, Ryu Mori, Hiromichi Murakami, Hitoshi Koga

Background: Emergency cricothyrotomy (CTM) is a rare but life-saving procedure performed under "cannot intubate, cannot oxygenate" (CICO) conditions. This study describes five in-hospital CICO cases requiring CTM, including one improvised procedure performed in a psychiatric ward without a formal airway kit, to highlight the procedural challenges and institutional preparedness.

Methods: This retrospective case series included five consecutive patients treated between April 2021 and April 2024. Data on patient demographics, causes of airway obstruction, procedural techniques, operator experience, and outcomes were also collected.

Results: CTM was successful in all patients on the first attempt, and they all survived and were successfully discharged. However, one patient developed hypoxic encephalopathy.

Conclusions: CTM remains a rare but essential life-saving intervention for in-hospital CICO cases. Institutional preparedness - including standardized kits, simulation-based training, and regular competency maintenance - is crucial for improving safety and outcomes across hospital departments.

背景:急诊环甲环切开术(CTM)是一种在“不能插管,不能充氧”(CICO)条件下进行的罕见但挽救生命的手术。本研究描述了五个需要CTM的住院CICO病例,包括一个在没有正式气道工具包的精神病房进行的临时手术,以突出程序挑战和机构准备。方法:该回顾性病例系列包括2021年4月至2024年4月期间连续治疗的5例患者。还收集了患者人口统计学、气道阻塞原因、手术技术、操作人员经验和结果的数据。结果:所有患者首次行CTM治疗均成功,全部存活出院。然而,一名患者发生了缺氧性脑病。结论:CTM仍然是一种罕见但必要的挽救住院CICO患者生命的干预措施。机构准备——包括标准化工具包、基于模拟的培训和定期能力维护——对于提高医院各部门的安全性和结果至关重要。
{"title":"Emergency cricothyrotomy in five in-hospital \"cannot intubate, cannot oxygenate\" cases: a case series.","authors":"Munehiro Yoshitomi, Syuichirou Sagara, Yuuji Tokuda, Tomohiro Inoue, Yoshikuni Koutaki, Naoyuki Tokuyama, Takaaki Mabe, Aoi Ichikawa, Syunsuke Hisaka, Naoto Chuman, Miki Yamamoto, Ryu Mori, Hiromichi Murakami, Hitoshi Koga","doi":"10.1097/MS9.0000000000004680","DOIUrl":"10.1097/MS9.0000000000004680","url":null,"abstract":"<p><strong>Background: </strong>Emergency cricothyrotomy (CTM) is a rare but life-saving procedure performed under \"cannot intubate, cannot oxygenate\" (CICO) conditions. This study describes five in-hospital CICO cases requiring CTM, including one improvised procedure performed in a psychiatric ward without a formal airway kit, to highlight the procedural challenges and institutional preparedness.</p><p><strong>Methods: </strong>This retrospective case series included five consecutive patients treated between April 2021 and April 2024. Data on patient demographics, causes of airway obstruction, procedural techniques, operator experience, and outcomes were also collected.</p><p><strong>Results: </strong>CTM was successful in all patients on the first attempt, and they all survived and were successfully discharged. However, one patient developed hypoxic encephalopathy.</p><p><strong>Conclusions: </strong>CTM remains a rare but essential life-saving intervention for in-hospital CICO cases. Institutional preparedness - including standardized kits, simulation-based training, and regular competency maintenance - is crucial for improving safety and outcomes across hospital departments.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"1221-1224"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuromyelitis optica spectrum disorder in an 11-year-old: a case report in a pediatric patient from Nepal. 11岁儿童视神经脊髓炎谱系障碍:尼泊尔儿科患者一例报告。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2026-01-20 eCollection Date: 2026-02-01 DOI: 10.1097/MS9.0000000000004760
Prakash Thapa, Sriram Kc, Bulbul Pradhan, Inesh Khanal, Aakripa R Shrestha

Introduction and importance: Neuromyelitis optica spectrum disorder (NMOSD) is an auto-immune inflammatory disorder of the central nervous system mediated by auto-antibodies against Aquaporin-4 (AQP4). It causes vision impairment, vomiting, and paralysis.

Case presentation: We report a case of an 11-year-old Nepalese girl who initially presented with persistent vomiting for 2 months, followed by progressive limb weakness and facial asymmetry. She was initially misdiagnosed as gastroduodenitis with mesenteric lymphadenitis and later with major depressive illness and dissociative motor disorder. Neurological examination revealed multiple cranial nerve palsies and upper motor neuron signs. Magnetic resonance imaging (MRI) of the brain and cervical spine demonstrated long segment T2 hyper-intensities involving the medulla, cervicomedullary junction, and cervical spinal cord which was highly suggestive of transverse myelitis with postrema lesions. Serum anti-AQP4 antibody testing done by indirect immunofluorescence assay was positive which confirmed NMOSD. The patient was treated with intravenous methylprednisolone pulse therapy followed by intravenous immunoglobulin and transitioned to oral prednisolone with gradual improvement in neurological function.

Clinical discussion: This case highlights diagnostic challenge of NMOSD, particularly when presented with area postrema syndrome without early neurological findings. Such atypical presentations are frequently mistaken for gastrointestinal or psychiatric conditions, delaying appropriate diagnosis and management. MRI findings and a positive anti-AQP-4 antibody remain key to confirming the diagnosis. Early initiation of immunotherapy is essential to prevent irreversible neurological deficits.

Conclusion: NMOSD should be considered in children presenting with unexplained persistent vomiting and subsequent neurological deficits. A high index of suspicion, prompt antibody testing, and timely immunotherapy are vital for favorable outcomes.

简介及重要性:视神经脊髓炎谱系障碍(NMOSD)是一种由抗水通道蛋白-4 (AQP4)自身抗体介导的中枢神经系统自身免疫性炎症性疾病。它会导致视力受损、呕吐和瘫痪。病例介绍:我们报告一例11岁尼泊尔女孩,最初表现为持续呕吐2个月,随后出现进行性肢体无力和面部不对称。她最初被误诊为胃十二指肠炎合并肠系膜淋巴结炎,后来被误诊为重度抑郁症和解离性运动障碍。神经学检查显示多发性脑神经麻痹和上运动神经元征象。脑和颈椎的磁共振成像(MRI)显示长段T2高强度累及髓质、颈髓交界处和颈脊髓,高度提示横贯脊髓炎伴术后病变。间接免疫荧光法检测血清aqp4抗体阳性,证实为NMOSD。患者接受静脉注射甲基强的松龙脉冲治疗,随后静脉注射免疫球蛋白,并过渡到口服强的松龙,神经功能逐渐改善。临床讨论:该病例强调了NMOSD的诊断挑战,特别是当出现区域后综合征而没有早期神经学表现时。这种不典型的表现经常被误认为胃肠道或精神疾病,延误了适当的诊断和治疗。MRI结果和抗aqp -4抗体阳性仍然是确诊的关键。早期开始免疫治疗对于预防不可逆转的神经功能缺陷至关重要。结论:在出现不明原因的持续性呕吐和随后的神经功能障碍的儿童中应考虑NMOSD。高怀疑指数,及时的抗体检测和及时的免疫治疗对良好的结果至关重要。
{"title":"Neuromyelitis optica spectrum disorder in an 11-year-old: a case report in a pediatric patient from Nepal.","authors":"Prakash Thapa, Sriram Kc, Bulbul Pradhan, Inesh Khanal, Aakripa R Shrestha","doi":"10.1097/MS9.0000000000004760","DOIUrl":"10.1097/MS9.0000000000004760","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Neuromyelitis optica spectrum disorder (NMOSD) is an auto-immune inflammatory disorder of the central nervous system mediated by auto-antibodies against Aquaporin-4 (AQP4). It causes vision impairment, vomiting, and paralysis.</p><p><strong>Case presentation: </strong>We report a case of an 11-year-old Nepalese girl who initially presented with persistent vomiting for 2 months, followed by progressive limb weakness and facial asymmetry. She was initially misdiagnosed as gastroduodenitis with mesenteric lymphadenitis and later with major depressive illness and dissociative motor disorder. Neurological examination revealed multiple cranial nerve palsies and upper motor neuron signs. Magnetic resonance imaging (MRI) of the brain and cervical spine demonstrated long segment T2 hyper-intensities involving the medulla, cervicomedullary junction, and cervical spinal cord which was highly suggestive of transverse myelitis with postrema lesions. Serum anti-AQP4 antibody testing done by indirect immunofluorescence assay was positive which confirmed NMOSD. The patient was treated with intravenous methylprednisolone pulse therapy followed by intravenous immunoglobulin and transitioned to oral prednisolone with gradual improvement in neurological function.</p><p><strong>Clinical discussion: </strong>This case highlights diagnostic challenge of NMOSD, particularly when presented with area postrema syndrome without early neurological findings. Such atypical presentations are frequently mistaken for gastrointestinal or psychiatric conditions, delaying appropriate diagnosis and management. MRI findings and a positive anti-AQP-4 antibody remain key to confirming the diagnosis. Early initiation of immunotherapy is essential to prevent irreversible neurological deficits.</p><p><strong>Conclusion: </strong>NMOSD should be considered in children presenting with unexplained persistent vomiting and subsequent neurological deficits. A high index of suspicion, prompt antibody testing, and timely immunotherapy are vital for favorable outcomes.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 2","pages":"2061-2066"},"PeriodicalIF":1.6,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12889369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Annals of Medicine and Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1