{"title":"Dystonia Secondary to Intramedullary Lesion of Spinal Cord: A Case Report.","authors":"Hardeep Jogi, Arvind Kankane, Vikas Jain, Patel G Kumar, Preeti Gupta","doi":"10.4103/aian.aian_424_25","DOIUrl":"https://doi.org/10.4103/aian.aian_424_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145740186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-10DOI: 10.4103/aian.aian_635_25
Meena Chandu, Divyani Garg, Ajay Garg, Laveleen Singh, Govind K Makharia, Lekshmi S Hema, Divya M Radhakrishnan, Shailesh B Gaikwad, Achal K Srivastava, Ayush Agarwal
{"title":"Cerebral Venous Sinus Thrombosis as the Initial Presentation of Coeliac Disease in a Young Male with Iron Deficiency Anemia.","authors":"Meena Chandu, Divyani Garg, Ajay Garg, Laveleen Singh, Govind K Makharia, Lekshmi S Hema, Divya M Radhakrishnan, Shailesh B Gaikwad, Achal K Srivastava, Ayush Agarwal","doi":"10.4103/aian.aian_635_25","DOIUrl":"https://doi.org/10.4103/aian.aian_635_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145713017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08DOI: 10.4103/aian.aian_848_25
Vishwajeet A Burungale, Kshitij Malik, Shreya Vats, Ajay K Vats, Ramesh Rohiwal, Sudhir Kothari
{"title":"Passive Head Yawing as a Diagnostic Aid in Bow Hunter's Syndrome: A Rare Case of Bilateral Thrombosed Vertebral Artery Dissection Without Structural Compression.","authors":"Vishwajeet A Burungale, Kshitij Malik, Shreya Vats, Ajay K Vats, Ramesh Rohiwal, Sudhir Kothari","doi":"10.4103/aian.aian_848_25","DOIUrl":"10.4103/aian.aian_848_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145712739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-06DOI: 10.4103/aian.aian_795_25
Jayaram Saibaba, Saranya B Gomathy, Ramkumar Sugumaran, Sunil K Narayan
{"title":"Progressive Supranuclear Palsy or Something More? Unveiling Late-Onset Wilson's Disease.","authors":"Jayaram Saibaba, Saranya B Gomathy, Ramkumar Sugumaran, Sunil K Narayan","doi":"10.4103/aian.aian_795_25","DOIUrl":"https://doi.org/10.4103/aian.aian_795_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145699798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-06DOI: 10.4103/aian.aian_800_25
Mimi Lam, Bhavesh Trikamji
{"title":"The Neuroradiologic Spectrum of Wolfram Syndrome.","authors":"Mimi Lam, Bhavesh Trikamji","doi":"10.4103/aian.aian_800_25","DOIUrl":"https://doi.org/10.4103/aian.aian_800_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145699778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral Dentate Nucleus Involvement in a Case of Enteric Fever-Triggered Minor Encephalopathy with Reversible Splenial Lesions.","authors":"Farsana Mustafa, Ravi Teja, Manvar Heer Sanjaykumar, Divyani Garg, Ayush Agarwal, Animesh Ray, Ajay Garg, Achal Kumar Srivastava","doi":"10.4103/aian.aian_688_25","DOIUrl":"https://doi.org/10.4103/aian.aian_688_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145666797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-28DOI: 10.4103/aian.aian_845_25
Vaibhav Bhandari, Savyasachi Jain, Ayush Agarwal, Divyani Garg, Shailesh B Gaikwad, Achal K Srivastava
{"title":"Fulminant Intracranial Hypertension Secondary to Multiple Cavernomas: A Rare Association.","authors":"Vaibhav Bhandari, Savyasachi Jain, Ayush Agarwal, Divyani Garg, Shailesh B Gaikwad, Achal K Srivastava","doi":"10.4103/aian.aian_845_25","DOIUrl":"https://doi.org/10.4103/aian.aian_845_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145627388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-28DOI: 10.4103/aian.aian_526_25
Iva Fiedorova, Sarka Banikova, Tomas Adamec, Adela Konde, Pavla Hanzlikova, Aravind Ganesh, Michal Bar, Ondrej Volny
Background and objectives: Robot-assisted gait training (RAGT) constitutes a modern neurorehabilitation approach. However, limited data are available regarding the efficacy of RAGT when combined with conventional rehabilitation in the early subacute phase of stroke. This pilot study assessed the additive impact of protocol-defined RAGT on functional ambulation categories (FACs), walking abilities, and balance.
Methods: This randomized controlled trial used a 1:1 Prospective Randomized Open Blinded End-point design (NCT04910217), comparing two groups: conventional rehabilitation and the RAGT group. All participants received protocol-defined conventional rehabilitation (15 sessions over 3 weeks). The RAGT group underwent additional sessions using the Lokomat Pro FreeD (15 sessions over 3 weeks). FAC, 10-meter Walk Test (10MWT), Timed Up and Go (TUG), and Berg Balance Scale (BBS) were assessed at 3 weeks and 3 months after randomization. In addition, the modified Rankin Scale was evaluated.
Results: Among 184 patients screened between June 1, 2020, and November 30, 2023, 42 were included (19 in the RAGT group and 23 in the conventional group). The median time from stroke to randomization was 13 days (interquartile range [IQR]: 11-16), and the median age was 67 years (IQR: 58-71). Both groups demonstrated improvements in FACs. Significantly, patients in the RAGT group showed better results in the endpoint of FAC improvement by 2 or more points (P = 0.044). Progress in TUG (P = 0.034) and BBS (P = 0.049) during the study period was significantly more favorable in the RAGT group.
Conclusions: The addition of RAGT to conventional rehabilitation in the subacute phase of stroke exhibited positive effects on improving gait, walking, and balance.Trial registration number: NCT04910217.
{"title":"Robot-Assisted Gait Therapy in the Subacute Phase of Ischemic Stroke: A Randomized Controlled Trial.","authors":"Iva Fiedorova, Sarka Banikova, Tomas Adamec, Adela Konde, Pavla Hanzlikova, Aravind Ganesh, Michal Bar, Ondrej Volny","doi":"10.4103/aian.aian_526_25","DOIUrl":"https://doi.org/10.4103/aian.aian_526_25","url":null,"abstract":"<p><strong>Background and objectives: </strong>Robot-assisted gait training (RAGT) constitutes a modern neurorehabilitation approach. However, limited data are available regarding the efficacy of RAGT when combined with conventional rehabilitation in the early subacute phase of stroke. This pilot study assessed the additive impact of protocol-defined RAGT on functional ambulation categories (FACs), walking abilities, and balance.</p><p><strong>Methods: </strong>This randomized controlled trial used a 1:1 Prospective Randomized Open Blinded End-point design (NCT04910217), comparing two groups: conventional rehabilitation and the RAGT group. All participants received protocol-defined conventional rehabilitation (15 sessions over 3 weeks). The RAGT group underwent additional sessions using the Lokomat Pro FreeD (15 sessions over 3 weeks). FAC, 10-meter Walk Test (10MWT), Timed Up and Go (TUG), and Berg Balance Scale (BBS) were assessed at 3 weeks and 3 months after randomization. In addition, the modified Rankin Scale was evaluated.</p><p><strong>Results: </strong>Among 184 patients screened between June 1, 2020, and November 30, 2023, 42 were included (19 in the RAGT group and 23 in the conventional group). The median time from stroke to randomization was 13 days (interquartile range [IQR]: 11-16), and the median age was 67 years (IQR: 58-71). Both groups demonstrated improvements in FACs. Significantly, patients in the RAGT group showed better results in the endpoint of FAC improvement by 2 or more points (P = 0.044). Progress in TUG (P = 0.034) and BBS (P = 0.049) during the study period was significantly more favorable in the RAGT group.</p><p><strong>Conclusions: </strong>The addition of RAGT to conventional rehabilitation in the subacute phase of stroke exhibited positive effects on improving gait, walking, and balance.Trial registration number: NCT04910217.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145627507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.4103/aian.aian_665_25
Gabriele Gaggero
{"title":"The Leptomeningeal Microenvironment in Metastasis: A Unique Central Nervous System Niche.","authors":"Gabriele Gaggero","doi":"10.4103/aian.aian_665_25","DOIUrl":"https://doi.org/10.4103/aian.aian_665_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145627497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Adult Ventriculitis due to Streptococcus pneumoniae with Obstructive Hydrocephalus: Role of Arachnoid Cyst as a Predisposing Factor.","authors":"Bhavani Madduluri, Phaninder Ln Madiraju, Surya Prabha Turaga","doi":"10.4103/aian.aian_406_25","DOIUrl":"https://doi.org/10.4103/aian.aian_406_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146123476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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