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Chelsea Watego: foregrounding Indigenous intellectual sovereignty. 切尔西-瓦特戈:凸显土著知识主权。
Pub Date : 2023-02-04 Epub Date: 2023-02-02 DOI: 10.1016/S0140-6736(23)00173-3
Aarathi Prasad
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引用次数: 0
"Affective Adjectives"の歴史的発達と使用頻度 --Aphra Behn, Jane Austen, Virginia Woolf, Hannah Moreの形容詞Lovelyを中心に “Affective Adjectives”の历史的発达と使用频度--Aphra Behn,Jane Austen,Virginia Woolf,Hannah Moreの形容词Lovelyを中心に
Pub Date : 2020-11-14 DOI: 10.14989/ALBION_65_35
矢橋 知枝
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引用次数: 0
Aboriginal and Torres Strait Islander health promotion programs for the prevention and management of chronic diseases: a scoping review protocol. 土著居民和托雷斯海峡岛民慢性病预防和管理健康促进计划:范围界定审查协议。
Pub Date : 2017-01-01 DOI: 10.11124/JBISRIR-2016-003021
Karla Canuto, Edoardo Aromataris, Craig Lockwood, Catalin Tufanaru, Alex Brown

Review objectives: The scoping review project will identify and describe the existing research on health promotion programs and activities focusing on modifying risk factors (specifically to reduce smoking and alcohol consumption, increase physical activity and improve nutrition and social and emotional wellbeing) and/or improving the management of chronic diseases (specifically obesity, type 2 diabetes, chronic kidney disease and cardiovascular disease) for Aboriginal and Torres Strait Islander peoples across a diverse range of health and community settings.

审查目标:范围界定审查项目将确定并描述有关健康促进计划和活动的现有研究,这些计划和活动的重点是在不同的卫生和社区环境中,为土著居民和托雷斯海峡岛民改变风险因素(特别是减少吸烟和饮酒、增加体育锻炼、改善营养以及社会和情感福祉)和/或改善慢性疾病(特别是肥胖症、2 型糖尿病、慢性肾病和心血管疾病)的管理。
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引用次数: 0
On ways of knowing in medicine. 关于医学的认知方式。
IF 14.6 Pub Date : 2015-12-07 DOI: 10.1503/cmaj.150673
Miriam Solomon
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引用次数: 0
Gender, medicine, and consumer culture in Victorian England: creating the kleptomaniac. 维多利亚时代英国的性别、医学和消费文化:造就了盗窃狂。
Pub Date : 2009-01-01
T Whitlock
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引用次数: 0
In-depth fluorescence lifetime imaging analysis revealing SNAP25A-Rabphilin 3A interactions. 深入的荧光寿命成像分析揭示了 SNAP25A-Rabphilin 3A 的相互作用。
IF 2.8 Pub Date : 2008-12-01 DOI: 10.1017/S1431927608080628
Jiung-De Lee, Ping-Chun Huang, Yi-Cheng Lin, Lung-Sen Kao, Chien-Chang Huang, Fu-Jen Kao, Chung-Chih Lin, De-Ming Yang

The high sensitivity and spatial resolution enabled by two-photon excitation fluorescence lifetime imaging microscopy/fluorescence resonance energy transfer (2PE-FLIM/FRET) provide an effective approach that reveals protein-protein interactions in a single cell during stimulated exocytosis. Enhanced green fluorescence protein (EGFP)-labeled synaptosomal associated protein of 25 kDa (SNAP25A) and red fluorescence protein (mRFP)-labeled Rabphillin 3A (RPH3A) were co-expressed in PC12 cells as the FRET donor and acceptor, respectively. The FLIM images of EGFP-SNAP25A suggested that SNAP25A/RPH3A interaction was increased during exocytosis. In addition, the multidimensional (three-dimensional with time) nature of the 2PE-FLIM image datasets can also resolve the protein interactions in the z direction, and we have compared several image analysis methods to extract more accurate and detailed information from the FLIM images. Fluorescence lifetime was fitted by using one and two component analysis. The lifetime FRET efficiency was calculated by the peak lifetime (taupeak) and the left side of the half-peak width (tau1/2), respectively. The results show that FRET efficiency increased at cell surface, which suggests that SNAP25A/RPH3A interactions take place at cell surface during stimulated exocytosis. In summary, we have demonstrated that the 2PE-FLIM/FRET technique is a powerful tool to reveal dynamic SNAP25A/RPH3A interactions in single neuroendocrine cells.

双光子激发荧光寿命成像显微镜/荧光共振能量转移(2PE-FLIM/FRET)具有高灵敏度和空间分辨率,是揭示单细胞在受刺激外渗过程中蛋白质之间相互作用的有效方法。增强绿色荧光蛋白(EGFP)标记的25 kDa突触体相关蛋白(SNAP25A)和红色荧光蛋白(mRFP)标记的Rabphillin 3A(RPH3A)分别作为FRET供体和受体共表达在PC12细胞中。EGFP-SNAP25A的FLIM图像表明,SNAP25A/RPH3A的相互作用在外排过程中有所增加。此外,2PE-FLIM 图像数据集的多维性(随时间变化的三维性)还能解析蛋白质在 Z 方向上的相互作用,我们比较了几种图像分析方法,以便从 FLIM 图像中提取更准确、更详细的信息。我们使用单分量和双分量分析法拟合了荧光寿命。荧光寿命 FRET 效率分别由峰值寿命(taupeak)和半峰宽度左侧(tau1/2)计算得出。结果表明,细胞表面的 FRET 效率增加,这表明 SNAP25A/RPH3A 在刺激外吞过程中会在细胞表面发生相互作用。综上所述,我们证明了 2PE-FLIM/FRET 技术是揭示单个神经内分泌细胞中 SNAP25A/RPH3A 动态相互作用的有力工具。
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引用次数: 11
Alyson Brown. English Society and the Prison: Time, Culture and Politics in the Development of the Modem Prison, 1850–1920 . Rochester, N. Y.: Boydell Press. 2003. Pp. vii, 205. $85.00. ISBN 1-84383-017-5. 艾莉森·布朗。《英国社会与监狱:现代监狱发展中的时间、文化和政治》,1850–1920年。纽约州罗切斯特:博伊德尔出版社。2003年,第vii页,第205页$85.00亿英镑1-84383-017-5。
Pub Date : 2005-12-01 DOI: 10.2307/4054639
D. Smith
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引用次数: 0
Pierre Chaplais. English Diplomatic Practice in the Middle Ages . London: Hambledon; dist. by Palgrave, New York, N.Y. 2003. Pp. xiii, 277 Pp. $34.95. ISBN 1-85285- 395-6. 皮埃尔·卓别林。中世纪的英国外交实践。伦敦:Hambledon;作者:Palgrave,纽约,纽约,2003年。第十二页,第277页,34.95美元。是1-85285-395-6。
Pub Date : 2005-01-01 DOI: 10.2307/4054590
N. Vincent
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引用次数: 0
Michael K. Jones. Bosworth 1485: Psychology of a Battle. Stroud, U. K.: Tempus Publishing; dist. by Trafalgar Square Publishing, North Pomfret, Vt. 2004. Pp. 255. $22.95 paper. ISBN 0-7524-2594-3. 迈克尔·k·琼斯。博斯沃思1485:战争的心理学。斯特劳德,英国:Tempus Publishing;特拉法加广场出版社,佛蒙特州北庞弗雷特2004年出版。255页。22.95美元。ISBN 0-7524-2594-3。
Pub Date : 2005-01-01 DOI: 10.2307/4054595
E. Furgol
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引用次数: 0
Tim Hitchcock and Heather Shore, eds. The Streets of London: From the Great Fire to the Great Stink . London: Rivers Oram Press; dist. by Independent Publishers Group, Chicago. 2003. Pp. xvi, 256. $55.00. ISBN 1-85489-130-8. 蒂姆·希区柯克和希瑟·肖尔主编。《伦敦街头:从大火到恶臭》伦敦:Rivers Oram出版社;2003年,芝加哥独立出版集团出版。第16页,256页。55.00美元。ISBN 1-85489-130-8。
Pub Date : 2005-01-01 DOI: 10.2307/4054612
Bob Bushaway
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引用次数: 0
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