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Clinical Outcomes and Applicability of Serratus Anterior Muscle Flap With Split Thickness Skin Graft in Thin Resurfacing Reconstructive Surgeries: A Retrospective Analysis. 前锯肌肌皮瓣与分割厚皮瓣移植在薄面皮重建手术中的临床效果和适用性:回顾性分析。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 DOI: 10.1097/SAP.0000000000004095
Yooseok Ha, Youn Hwan Kim

Abstract: This retrospective study evaluates the efficacy of the serratus anterior muscle (SAm) free flap combined with a split thickness skin graft (STSG) for thin resurfacing in reconstructive surgery, presenting an alternative to pure skin perforator flaps. It analyzes 14 SAm free flap procedures performed between January 2015 and December 2023. The study cohort comprised 5 women and 9 men, aged 31-80 years, addressing defects caused by infection, malignancy, burn, and trauma, located in various body parts.The study involves harvesting the SAm flap while focusing on anatomical features such as the distinct direction of muscle fibers and the surface location of the vascular pedicle for efficient dissection. It emphasizes the anatomical advantages of the SAm flap, such as robust vascular supply, controlled flap thickness, and preservation of the long thoracic nerve, making it suitable for a range of surgical needs. Complications included STSG loss, partial necrosis, and infection, all managed effectively. Postoperative shoulder function assessment showed no significant impairment.Results demonstrated the successful application of the SAm flap in all cases, with an average flap dimension of 38.21 cm2 and pedicle length of 7.3 cm. The average operation time was 122.1 minutes. The study underscores the SAm flap's adaptability, versatility, and minimal donor site morbidity.It concludes that the SAm flap, in conjunction with STSG, is a viable alternative for thin resurfacing in reconstructive surgery. However, limitations such as the small sample size and procedural variability suggest the need for further research to fully establish the flap's potential in diverse surgical contexts.

摘要:这项回顾性研究评估了前锯肌游离皮瓣与分层厚度皮肤移植(STSG)结合用于整形手术薄层重塑的疗效,为纯皮肤穿孔器皮瓣提供了一种替代方案。研究分析了2015年1月至2023年12月期间进行的14例SAm游离皮瓣手术。研究对象包括5名女性和9名男性,年龄在31-80岁之间,涉及身体各部位因感染、恶性肿瘤、烧伤和外伤造成的缺损。研究涉及SAm皮瓣的采集,同时关注解剖学特征,如肌肉纤维的明显方向和血管蒂的表面位置,以实现高效解剖。研究强调了SAm皮瓣的解剖学优势,如强大的血管供应、可控的皮瓣厚度和长胸神经的保留,使其适用于各种手术需求。并发症包括STSG缺失、部分坏死和感染,均得到了有效控制。结果显示,所有病例都成功应用了SAm皮瓣,皮瓣平均面积为38.21平方厘米,蒂长为7.3厘米。平均手术时间为 122.1 分钟。该研究强调了SAm皮瓣的适应性、多功能性和最小的供体部位发病率。研究得出结论,SAm皮瓣与STSG相结合,是重建手术中薄层再植的可行替代方法。不过,由于样本量较小和手术的可变性等局限性,还需要进一步研究,以充分确定该皮瓣在不同手术环境中的潜力。
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引用次数: 0
One-Stage Surgical Resection and Functional Reconstruction for Upper Limb Soft Tissue Sarcoma. 上肢软组织肉瘤的一期手术切除和功能重建。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 DOI: 10.1097/SAP.0000000000004107
Arianna Gatto, Erica M Cavalli, Sara Stucchi, Giorgio Giacomini, Michael Belingheri, Stefano Radaelli, Alessandro Gronchi, Andrea Marchesi

Background: Currently, the gold standard of treatment for extremity soft tissue sarcoma (STS) is limb-sparing surgery. When the upper extremity is involved, the functional outcome is frequently poor. A 1-step resection and functional reconstruction would be advisable to obtain a fast recovery. Our study aims at retrospectively analyzing our case series of immediate nerves and tendons reconstructions of the upper limb after STS resection, while combining a review of the literature.

Methods: A retrospective review was conducted on a consecutive series of patients who underwent an immediate functional reconstruction after STS resection of the upper limb between 2015 and 2022 among the IRCCS Foundation "Istituto Nazionale dei Tumori." The Disabilities of the Arm, Shoulder and Hand (DASH) score was considered the primary outcome. The obtained DASH scores were compared through groups that underwent different reconstructive procedures. The literature review was conducted according to the PRISMA (Preferred Reporting Items for Systematic review and Meta-Analysis) criteria among 3 databases (PubMed, EMBASE, and Cochrane) using the search parameters "(((upper extremity) OR (upper limb)) AND (functional reconstruction) AND (soft tissue sarcoma)."

Results: Between 2015 and 2022, 52 patients required a functional reconstruction. The mean follow-up time was 49.63 months. The DASH score analysis reported a mean value of 44.1 ± 26.7. A statistically significant difference was found between groups who underwent different reconstruction techniques, whereas no difference was found regarding exposure to neoadjuvant radiation therapy. The literature review reported few articles focusing on immediate functional reconstruction after STS resection, and only 6 articles were included in the review.

Conclusions: Our review aimed at reporting our case series of immediate functional reconstructions after STS of the upper extremity, which is currently the most substantial one reported in literature to set an effective baseline for further studies in the field.

背景:目前,治疗四肢软组织肉瘤(STS)的金标准是保肢手术。当上肢受累时,功能效果往往不佳。一步到位的切除和功能重建是快速康复的明智之举。我们的研究旨在回顾性分析我们在 STS 切除术后立即进行上肢神经和肌腱重建的病例系列,同时结合文献综述:对2015年至2022年间在IRCCS基金会 "Istituto Nazionale dei Tumori "接受上肢STS切除术后立即进行功能重建的连续系列患者进行回顾性分析。手臂、肩部和手部残疾(DASH)评分被视为主要结果。通过对接受不同重建手术的组别进行比较,得出DASH评分。根据PRISMA(系统综述和Meta分析的首选报告项目)标准,在3个数据库(PubMed、EMBASE和Cochrane)中进行了文献综述,检索参数为"((上肢)或(上肢))和(功能重建)和(软组织肉瘤)":2015年至2022年间,52名患者需要进行功能重建。平均随访时间为 49.63 个月。DASH评分分析报告的平均值为(44.1 ± 26.7)。接受不同重建技术的组别之间存在明显统计学差异,而接受新辅助放疗的组别之间则无差异。文献综述中关于STS切除术后即刻功能重建的文章很少,仅有6篇文章被纳入综述:我们的综述旨在报告我们的上肢 STS 术后即刻功能重建的病例系列,这是目前文献报道最多的,为该领域的进一步研究设定了有效的基线。
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引用次数: 0
Pediatric Intranasal Lobular Capillary Hemangioma: A Scoping Review and Multimedia Case Presentation. 小儿鼻腔内叶状毛细血管瘤:范围综述和多媒体病例展示。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 Epub Date: 2024-09-03 DOI: 10.1097/SAP.0000000000004094
Bastien A Valencia-Sanchez, Tom Shokri, Christopher L Kalmar, Vijay A Patel

Study design: Systematic, scoping literature review and case presentation.

Objective: The goal of this study is to review current literature on management trends and outcomes of pediatric intranasal lobular capillary hemangioma (ILCH).

Case presentation: A 14-year-old male patient presented with a 15-month history of unilateral epistaxis, nasal congestion, and mouth breathing. Further workup revealed a pale nasal mass obstructing the right nasal cavity. The patient was successfully treated using a minimally invasive endoscopic endonasal approach for mass resection and nasal floor free mucosal graft for septal reconstruction.

Methods: Independent queries of the PubMed Central, MEDLINE, and Bookshelf databases were performed; articles from 1990 to 2023 were abstracted. All studies that described pediatric ILCH using the Boolean method and relevant search term combinations, including "Intranasal," "Lobular capillary hemangioma," "Pyogenic granuloma," "Pediatric," "Outcome," and "Management," were collected for subsequent analysis.

Results: A total of 407 relevant unique articles were identified for analysis. Of these, 19 articles were deemed appropriate for inclusion in this literature review. Twenty-two pediatric ILCH cases were identified with a mean age at diagnosis of 10.5 years. The majority of cases occurred in males and presented with recurrent epistaxis and nasal obstruction. Most lesions originated from the anterior nasal septum and were resected using an endoscopic endonasal approach with no recurrence at last follow-up.

Conclusions: Pediatric ILCH, a benign vascular neoplasm, often presents with unilateral nasal obstruction and severe, refractory epistaxis. This comprehensive review aims to highlight the importance of including this lesion in the differential diagnosis for unilateral nasal obstruction and epistaxis in young children.

研究设计:系统性、范围性文献综述和病例介绍:本研究旨在回顾有关小儿鼻内小叶毛细血管瘤(ILCH)管理趋势和结果的现有文献:一名 14 岁男性患者因单侧鼻衄、鼻塞和口呼吸就诊 15 个月。进一步检查发现,一个苍白的鼻腔肿块阻塞了右侧鼻腔。采用微创鼻内镜方法切除肿块,并进行鼻底游离粘膜移植重建鼻中隔,患者的治疗获得成功:对PubMed Central、MEDLINE和Bookshelf数据库进行了独立查询;摘录了1990年至2023年的文章。使用布尔法和相关搜索词组合(包括 "鼻内"、"叶状毛细血管瘤"、"化脓性肉芽肿"、"儿科"、"结果 "和 "管理")收集了所有描述小儿ILCH的研究,以便进行后续分析:结果:共找到 407 篇相关文章进行分析。结果:共找到 407 篇相关文章进行分析,其中 19 篇被认为适合纳入本文献综述。共发现22例小儿ILCH病例,诊断时的平均年龄为10.5岁。大多数病例为男性,表现为反复鼻衄和鼻塞。大多数病灶来自鼻中隔前部,采用鼻内镜方法切除,最近一次随访时未见复发:结论:小儿ILCH是一种良性血管肿瘤,通常表现为单侧鼻塞和严重的难治性鼻衄。本综述旨在强调将这种病变纳入幼儿单侧鼻腔阻塞和鼻衄的鉴别诊断中的重要性。
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引用次数: 0
Intraoperative Measurement-Based Approach to Supratip Deformity in Open Structural Rhinoplasty. 基于术中测量的开放式结构鼻整形术中鼻尖上畸形的处理方法。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 Epub Date: 2024-07-08 DOI: 10.1097/SAP.0000000000004049
Serhat Şibar, Ayhan Işık Erdal, Mert Doruk, Nurullah Gündüz, Mehmet Fatih Özçiler

Background: Supratip deformity is one of the most common complications after open rhinoplasty. This study aimed to define a new risk scoring system for supratip deformity and determine the distances that should be left between the tip defining point (TDP) and anterior septal angle (ASA) to prevent it.

Methods: Four hundred sixty-nine patients who underwent open rhinoplasty between 2018-2022 were included in this retrospective study. The patients were evaluated according to the risk scoring system consisting of four parameters (skin thickness, lower lateral cartilage anatomy, amount of hump resection, and soft tissue procedures). Because of the presence of supratip deformity at the postoperative 12th month, the patients were divided into two groups: (i) without supratip deformity (n = 418) and (ii) with supratip deformity (n = 51). Statistical inferences were made regarding the development of supratip deformity by evaluating the relationship between the risk scores and the intraoperative TDP-ASA distances.

Results: There was a significant difference between the groups in risk scores ( P < 0.05). In cases with high-risk scores, it was calculated that the probability of developing supratip deformity decreased significantly when the TDP-ASA distance was above 7.5 mm and increased significantly when the TDP-ASA distance was below 6.5 mm. In cases with low-risk scores, it was found that the probability of developing supratip deformity was reduced considerably when the TDP-ASA distance was over 6.0 mm.

Conclusions: The authors recommend keeping the TDP-ASA distance above 6.0 mm in low-risk patients and 7.5 mm in high-risk patients to avoid supratip deformity.

背景:鼻尖上畸形是开放式鼻整形术后最常见的并发症之一。本研究旨在定义一种新的鼻尖上畸形风险评分系统,并确定鼻尖定义点(TDP)和鼻中隔前角(ASA)之间应留出的距离,以预防鼻尖上畸形的发生:这项回顾性研究纳入了2018-2022年间接受开放式鼻整形术的469例患者。根据由四个参数(皮肤厚度、下外侧软骨解剖、驼峰切除量和软组织手术)组成的风险评分系统对患者进行评估。由于患者在术后第12个月出现上唇畸形,因此将患者分为两组:(i) 无上唇畸形组(n = 418)和(ii) 有上唇畸形组(n = 51)。通过评估风险评分与术中 TDP-ASA 距离之间的关系,对臀上畸形的发生进行统计推断:各组之间的风险评分差异明显(P<0.05)。根据计算,在高风险评分的病例中,当 TDP-ASA 距离超过 7.5 mm 时,发生唇上畸形的概率明显降低,而当 TDP-ASA 距离低于 6.5 mm 时,发生唇上畸形的概率明显增加。在低风险评分的病例中,发现当 TDP-ASA 距离超过 6.0 mm 时,发生唇上畸形的概率大大降低:作者建议将低风险患者的 TDP-ASA 距离保持在 6.0 毫米以上,高风险患者保持在 7.5 毫米以上,以避免唇上畸形。
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引用次数: 0
Assessing the Readability of Online English and Spanish Resources for Polydactyly and Syndactyly. 评估有关多指畸形和并指畸形的在线英语和西班牙语资源的可读性。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 DOI: 10.1097/SAP.0000000000004121
Ashley Shin, Praneet S Paidisetty, Surya Chivukula, Leonard Kuan-Pei Wang, Wendy Chen

Introduction: Online patient education materials (PEMs) that are difficult to read disproportionately affect patients with low health literacy and educational attainment. Patients may not be fully informed or empowered to engage meaningfully with providers and advocate for their goals. We aim to assess the readability of online PEMs regarding polydactyly and syndactyly.

Methods: Google was used to query "polydactyly" and "syndactyly" in English and Spanish. The first 50 results were categorized into institutional (government, medical school, teaching hospital), noninstitutional (private practice, blog), and academic (journal articles, book chapters). Readability scores were generated using the Simple Measure of Gobbledygook and Spanish Simple Measure of Gobbledygook scales.

Results: All polydactyly PEMs and >95% of syndactyly PEMs exceeded the National Institutes of Health recommended 6th-grade reading level. Altogether, English PEMs had an average reading level of a university freshman and Spanish PEMs had an average reading level of nearly a high school sophomore. For both diagnoses, English PEMs were harder to read than Spanish PEMs overall and when compared across the 3 categories between the 2 languages. Generally, noninstitutional PEMs were more difficult to read than their institutional counterparts.

Conclusions: To improve patient education, health literacy, and language equity, online resources for polydactyly and syndactyly should be written at the 6th-grade level. Currently, these PEMs are too advanced, which can make accessing, understanding, and pursuing healthcare decisions more challenging. Understanding health conditions and information is crucial to empower patients, regardless of literacy.

简介:难以阅读的在线患者教育资料(PEMs)对健康知识水平和教育程度较低的患者造成了极大的影响。患者可能无法充分了解相关信息,也没有能力与医疗服务提供者进行有意义的沟通,并为自己的目标进行宣传。我们旨在评估有关多指畸形和并指畸形的在线 PEM 的可读性:使用谷歌搜索英语和西班牙语的 "polydactyly "和 "syndactyly"。前 50 个结果分为机构(政府、医学院、教学医院)、非机构(私人诊所、博客)和学术(期刊论文、书籍章节)。可读性评分采用 "Gobbledygook 简易量表 "和 "Gobbledygook 西班牙语简易量表 "进行计算:结果:所有多指畸形儿童阅读材料和超过 95% 的并指畸形儿童阅读材料都超过了美国国立卫生研究院推荐的六年级阅读水平。总之,英语型多指畸形患儿的平均阅读水平相当于大学一年级学生,而西班牙语型多指畸形患儿的平均阅读水平接近高中二年级学生。就两种诊断而言,总体而言,英文患者的阅读能力要比西班牙文患者的阅读能力强,而且在两种语言的 3 个类别之间进行比较时也是如此。一般来说,非医疗机构的 PEM 比医疗机构的 PEM 更难阅读:结论:为了改善患者教育、健康知识普及和语言公平,多指畸形和并指畸形的在线资源应该以六年级的水平编写。目前,这些多指畸形和并指畸形教材的内容过于深奥,这使得获取、理解和做出医疗决策变得更具挑战性。无论识字与否,了解健康状况和信息对于增强患者的能力都至关重要。
{"title":"Assessing the Readability of Online English and Spanish Resources for Polydactyly and Syndactyly.","authors":"Ashley Shin, Praneet S Paidisetty, Surya Chivukula, Leonard Kuan-Pei Wang, Wendy Chen","doi":"10.1097/SAP.0000000000004121","DOIUrl":"10.1097/SAP.0000000000004121","url":null,"abstract":"<p><strong>Introduction: </strong>Online patient education materials (PEMs) that are difficult to read disproportionately affect patients with low health literacy and educational attainment. Patients may not be fully informed or empowered to engage meaningfully with providers and advocate for their goals. We aim to assess the readability of online PEMs regarding polydactyly and syndactyly.</p><p><strong>Methods: </strong>Google was used to query \"polydactyly\" and \"syndactyly\" in English and Spanish. The first 50 results were categorized into institutional (government, medical school, teaching hospital), noninstitutional (private practice, blog), and academic (journal articles, book chapters). Readability scores were generated using the Simple Measure of Gobbledygook and Spanish Simple Measure of Gobbledygook scales.</p><p><strong>Results: </strong>All polydactyly PEMs and >95% of syndactyly PEMs exceeded the National Institutes of Health recommended 6th-grade reading level. Altogether, English PEMs had an average reading level of a university freshman and Spanish PEMs had an average reading level of nearly a high school sophomore. For both diagnoses, English PEMs were harder to read than Spanish PEMs overall and when compared across the 3 categories between the 2 languages. Generally, noninstitutional PEMs were more difficult to read than their institutional counterparts.</p><p><strong>Conclusions: </strong>To improve patient education, health literacy, and language equity, online resources for polydactyly and syndactyly should be written at the 6th-grade level. Currently, these PEMs are too advanced, which can make accessing, understanding, and pursuing healthcare decisions more challenging. Understanding health conditions and information is crucial to empower patients, regardless of literacy.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"93 5","pages":"546-550"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced Diabetic Rat Wound Healing by Platelet-Rich Plasma Adhesion Zwitterionic Hydrogel. 富血小板血浆黏附性聚合水凝胶促进糖尿病大鼠伤口愈合
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 Epub Date: 2024-09-19 DOI: 10.1097/SAP.0000000000004059
Zeya Zhang, Yanyong Zhao
{"title":"Enhanced Diabetic Rat Wound Healing by Platelet-Rich Plasma Adhesion Zwitterionic Hydrogel.","authors":"Zeya Zhang, Yanyong Zhao","doi":"10.1097/SAP.0000000000004059","DOIUrl":"10.1097/SAP.0000000000004059","url":null,"abstract":"","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":" ","pages":"649"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing Provider and ChatGPT Responses to Breast Reconstruction Patient Questions in the Electronic Health Record. 比较医护人员和 ChatGPT 对电子健康记录中乳房再造患者问题的回答。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 DOI: 10.1097/SAP.0000000000004090
Daniel Soroudi, Aileen Gozali, Jacquelyn A Knox, Nisha Parmeshwar, Ryan Sadjadi, Jasmin C Wilson, Seung Ah Lee, Merisa L Piper

Background: Patient-directed Electronic Health Record (EHR) messaging is used as an adjunct to enhance patient-physician interactions but further burdens the physician. There is a need for clear electronic patient communication in all aspects of medicine, including plastic surgery. We can potentially utilize innovative communication tools like ChatGPT. This study assesses ChatGPT's effectiveness in answering breast reconstruction queries, comparing its accuracy, empathy, and readability with healthcare providers' responses.

Methods: Ten deidentified questions regarding breast reconstruction were extracted from electronic messages. They were presented to ChatGPT3, ChatGPT4, plastic surgeons, and advanced practice providers for response. ChatGPT3 and ChatGPT4 were also prompted to give brief responses. Using 1-5 Likert scoring, accuracy and empathy were graded by 2 plastic surgeons and medical students, respectively. Readability was measured using Flesch Reading Ease. Grades were compared using 2-tailed t tests.

Results: Combined provider responses had better Flesch Reading Ease scores compared to all combined chatbot responses (53.3 ± 13.3 vs 36.0 ± 11.6, P < 0.001) and combined brief chatbot responses (53.3 ± 13.3 vs 34.7 ± 12.8, P < 0.001). Empathy scores were higher in all combined chatbot than in those from combined providers (2.9 ± 0.8 vs 2.0 ± 0.9, P < 0.001). There were no statistically significant differences in accuracy between combined providers and all combined chatbot responses (4.3 ± 0.9 vs 4.5 ± 0.6, P = 0.170) or combined brief chatbot responses (4.3 ± 0.9 vs 4.6 ± 0.6, P = 0.128).

Conclusions: Amid the time constraints and complexities of plastic surgery decision making, our study underscores ChatGPT's potential to enhance patient communication. ChatGPT excels in empathy and accuracy, yet its readability presents limitations that should be addressed.

背景:以患者为导向的电子健康记录(EHR)信息传递被用作加强医患互动的辅助手段,但却进一步加重了医生的负担。包括整形外科在内的所有医学领域都需要与患者进行清晰的电子交流。我们有可能利用像 ChatGPT 这样的创新交流工具。本研究评估了 ChatGPT 在回答乳房重建问题时的有效性,并将其准确性、同理心和可读性与医疗服务提供者的回答进行了比较:方法:从电子信息中提取了 10 个与乳房重建相关的去标识化问题。这些问题分别提交给 ChatGPT3、ChatGPT4、整形外科医生和高级医疗服务提供者进行回答。同时还提示 ChatGPT3 和 ChatGPT4 作出简短回答。2 名整形外科医生和医科学生分别采用 1-5 级李克特评分法对准确性和共鸣性进行评分。可读性采用 Flesch 阅读容易度进行测量。采用双尾 t 检验对评分进行比较:结果:与所有综合聊天机器人回复(53.3 ± 13.3 vs 36.0 ± 11.6,P < 0.001)和综合简短聊天机器人回复(53.3 ± 13.3 vs 34.7 ± 12.8,P < 0.001)相比,综合提供商回复的Flesch阅读易读性得分更高。所有综合聊天机器人的移情得分均高于综合提供者的移情得分(2.9 ± 0.8 vs 2.0 ± 0.9,P < 0.001)。在准确性方面,综合提供者与所有综合聊天机器人回复(4.3 ± 0.9 vs 4.5 ± 0.6,P = 0.170)或综合简短聊天机器人回复(4.3 ± 0.9 vs 4.6 ± 0.6,P = 0.128)之间没有明显的统计学差异:在时间紧迫和整形手术决策复杂的情况下,我们的研究强调了 ChatGPT 在加强患者沟通方面的潜力。ChatGPT 在同理心和准确性方面表现出色,但其可读性存在局限性,应加以解决。
{"title":"Comparing Provider and ChatGPT Responses to Breast Reconstruction Patient Questions in the Electronic Health Record.","authors":"Daniel Soroudi, Aileen Gozali, Jacquelyn A Knox, Nisha Parmeshwar, Ryan Sadjadi, Jasmin C Wilson, Seung Ah Lee, Merisa L Piper","doi":"10.1097/SAP.0000000000004090","DOIUrl":"10.1097/SAP.0000000000004090","url":null,"abstract":"<p><strong>Background: </strong>Patient-directed Electronic Health Record (EHR) messaging is used as an adjunct to enhance patient-physician interactions but further burdens the physician. There is a need for clear electronic patient communication in all aspects of medicine, including plastic surgery. We can potentially utilize innovative communication tools like ChatGPT. This study assesses ChatGPT's effectiveness in answering breast reconstruction queries, comparing its accuracy, empathy, and readability with healthcare providers' responses.</p><p><strong>Methods: </strong>Ten deidentified questions regarding breast reconstruction were extracted from electronic messages. They were presented to ChatGPT3, ChatGPT4, plastic surgeons, and advanced practice providers for response. ChatGPT3 and ChatGPT4 were also prompted to give brief responses. Using 1-5 Likert scoring, accuracy and empathy were graded by 2 plastic surgeons and medical students, respectively. Readability was measured using Flesch Reading Ease. Grades were compared using 2-tailed t tests.</p><p><strong>Results: </strong>Combined provider responses had better Flesch Reading Ease scores compared to all combined chatbot responses (53.3 ± 13.3 vs 36.0 ± 11.6, P < 0.001) and combined brief chatbot responses (53.3 ± 13.3 vs 34.7 ± 12.8, P < 0.001). Empathy scores were higher in all combined chatbot than in those from combined providers (2.9 ± 0.8 vs 2.0 ± 0.9, P < 0.001). There were no statistically significant differences in accuracy between combined providers and all combined chatbot responses (4.3 ± 0.9 vs 4.5 ± 0.6, P = 0.170) or combined brief chatbot responses (4.3 ± 0.9 vs 4.6 ± 0.6, P = 0.128).</p><p><strong>Conclusions: </strong>Amid the time constraints and complexities of plastic surgery decision making, our study underscores ChatGPT's potential to enhance patient communication. ChatGPT excels in empathy and accuracy, yet its readability presents limitations that should be addressed.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"93 5","pages":"541-545"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of a Regenerative Protocol for Recellularizing Human Auricular Cartilage Scaffolds. 确定人耳廓软骨支架再细胞化的再生方案。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 DOI: 10.1097/SAP.0000000000004137
Mary E Ziegler, Leonardo Alaniz, Nawal Khan, Melinda Lem, Jason Pham, Arya Sherafat, Jacklyn Melkonian, Nikhil Prabhakar, Madelyn Shay, Kadir B Oyur, Miles J Pfaff, Alan D Widgerow

Objective: Utilizing biological scaffolds for cartilage tissue engineering is a promising tool for improving auricular reconstruction. Decellularized auricular scaffolds provide a means of regenerating cartilage for in vivo implantation, but identifying the ideal regenerative mix remains challenging.

Methods: Human cadaver auricular cartilage was decellularized and recellularized with either auricular chondrocytes alone, auricular chondrocytes with adipose-derived stem cells, or both cells with platelet-rich plasma. Confirmation of decellularization and recellularization was done by hematoxylin and eosin staining. Extracellular matrix preservation and production were determined by Masson's trichrome, Alcian blue, and Verhoeff-van Gieson staining. Collagen II assessments were made using immunohistochemistry.

Results: Decellularization of cadaver auricular cartilage was confirmed by the absence of cells, reduction in glycosaminoglycans, and the preservation of collagen and elastin. Recellularization was more efficient when chondrocytes were seeded with adipose-derived stem cells, which was enhanced by adding platelet-rich plasma. Coculture with platelet-rich plasma yielded better total collagen (56% increase) and glycosaminoglycan (47% increase) induction. Moreover, when platelet-rich plasma was added, collagen II induction was significantly increased (42%; P < 0.05).

Conclusion: We identified a regenerative protocol that included auricular chondrocytes, adipose-derived stem cells, and platelet-rich plasma, which stimulated chondrogenesis on decellularized auricular cartilage. This finding provides a model to explore cartilage formation and the potential for improving auricular and cartilage-based reconstruction.

目的:利用生物支架进行软骨组织工程是改善耳廓重建的有效手段。方法:对人体尸体耳廓软骨进行脱细胞处理,然后用单独的耳廓软骨细胞、耳廓软骨细胞与脂肪来源干细胞或两种细胞与富血小板血浆进行再细胞化。脱细胞和再细胞化的确认是通过苏木精和伊红染色完成的。细胞外基质的保存和生成是通过马森三色染色法、阿尔西安蓝染色法和Verhoeff-van Gieson染色法确定的。使用免疫组化方法对胶原蛋白II进行评估:结果:尸体耳廓软骨的脱细胞化通过细胞的缺失、糖胺聚糖的减少以及胶原蛋白和弹性蛋白的保留得到了证实。当软骨细胞与脂肪来源的干细胞一起播种时,再细胞化的效率更高,加入富血小板血浆后,再细胞化的效率更高。与富血小板血浆共培养能更好地诱导总胶原蛋白(增加56%)和糖胺聚糖(增加47%)。此外,加入富血小板血浆后,胶原蛋白II的诱导率显著增加(42%;P < 0.05):我们确定了一种包括耳软骨细胞、脂肪来源干细胞和富血小板血浆的再生方案,它能刺激脱细胞耳软骨上的软骨生成。这一发现提供了一个探索软骨形成的模型,以及改善耳廓和软骨重建的潜力。
{"title":"Identification of a Regenerative Protocol for Recellularizing Human Auricular Cartilage Scaffolds.","authors":"Mary E Ziegler, Leonardo Alaniz, Nawal Khan, Melinda Lem, Jason Pham, Arya Sherafat, Jacklyn Melkonian, Nikhil Prabhakar, Madelyn Shay, Kadir B Oyur, Miles J Pfaff, Alan D Widgerow","doi":"10.1097/SAP.0000000000004137","DOIUrl":"10.1097/SAP.0000000000004137","url":null,"abstract":"<p><strong>Objective: </strong>Utilizing biological scaffolds for cartilage tissue engineering is a promising tool for improving auricular reconstruction. Decellularized auricular scaffolds provide a means of regenerating cartilage for in vivo implantation, but identifying the ideal regenerative mix remains challenging.</p><p><strong>Methods: </strong>Human cadaver auricular cartilage was decellularized and recellularized with either auricular chondrocytes alone, auricular chondrocytes with adipose-derived stem cells, or both cells with platelet-rich plasma. Confirmation of decellularization and recellularization was done by hematoxylin and eosin staining. Extracellular matrix preservation and production were determined by Masson's trichrome, Alcian blue, and Verhoeff-van Gieson staining. Collagen II assessments were made using immunohistochemistry.</p><p><strong>Results: </strong>Decellularization of cadaver auricular cartilage was confirmed by the absence of cells, reduction in glycosaminoglycans, and the preservation of collagen and elastin. Recellularization was more efficient when chondrocytes were seeded with adipose-derived stem cells, which was enhanced by adding platelet-rich plasma. Coculture with platelet-rich plasma yielded better total collagen (56% increase) and glycosaminoglycan (47% increase) induction. Moreover, when platelet-rich plasma was added, collagen II induction was significantly increased (42%; P < 0.05).</p><p><strong>Conclusion: </strong>We identified a regenerative protocol that included auricular chondrocytes, adipose-derived stem cells, and platelet-rich plasma, which stimulated chondrogenesis on decellularized auricular cartilage. This finding provides a model to explore cartilage formation and the potential for improving auricular and cartilage-based reconstruction.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"93 5","pages":"631-636"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resection Weight Formulas for Reduction Mammoplasty: A Systematic Review and Regression Analysis. 乳房缩小整形术的切除重量公式:系统回顾与回归分析
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-11-01 DOI: 10.1097/SAP.0000000000004114
Nisha Gupta, Christian X Lava, Sami Ferdousian, Karen R Li, Jenna C Bekeny, Kenneth L Fan

Purpose: Estimating resection weight for patients undergoing reduction mammoplasty (RM) informs surgical planning and outcomes. Existing formulas have limitations that make insurance coverage and accurate surgical planning challenging. We identified the most commonly used scales to evaluate their accuracy in estimating resection weight by applying them to a database of patients to compare calculated and actual resection weights.

Methods: A database search was conducted using combinations of relevant terms. A regression analysis was conducted using formulas with strong R2 values (0.72-0.93) on a cohort of 1128 RM patients at a single institution.

Results: A total of 570 articles were identified. Fourteen manuscripts (n = 2232 patients [3320 breasts]) were ultimately included for review. Data on incisional patterns, pedicle supply, and breast measurements, such as sternal notch to nipple distance (n = 8 [57.1%]) or nipple to inframammary fold distance (n = 5 [35.7%]), were recorded. R2 values in our cohort (>500 g, n = 891; <500 g, n = 237) were calculated via regression analyses with five formulas: Appel (0.391 vs 0.146), Boukovalas (0.3552 vs 0.043), Descamps (0.391 vs 0.238), Eder (0.328 vs 0.114), and Kocak (0.3283 vs R2 indeterminate).

Conclusions: Our analysis suggests that formulas reporting strong R2 values may have resulted from tailoring to surgeons' technique. Variation between cohorts is inevitable; however, we expect reliable results given our large sample. It is reasonable to conclude that existing formulas are not accurate representations of resection weights and thus are unreliable for surgical planning.

目的:估算接受乳房缩小成形术(RM)患者的切除重量可为手术规划和结果提供依据。现有的计算公式有其局限性,使保险范围和准确的手术计划面临挑战。我们确定了最常用的量表,通过将其应用于患者数据库来比较计算和实际切除重量,从而评估它们在估计切除重量方面的准确性:方法:使用相关术语组合进行数据库搜索。方法:使用相关术语组合进行数据库搜索,使用R2值较高(0.72-0.93)的公式对一家机构的1128名RM患者进行回归分析:结果:共发现 570 篇文章。最终有 14 篇文章(n = 2232 名患者 [3320 个乳房])被纳入审查范围。我们记录了有关切口模式、蒂供应和乳房测量的数据,如胸骨切迹到乳头的距离(n = 8 [57.1%])或乳头到乳房下皱褶的距离(n = 5 [35.7%])。我们队列中的 R2 值(大于 500 g,n = 891;结论:我们的分析表明,在我们的队列中,R2 值的计算公式具有很高的可信度:我们的分析表明,报告 R2 值较高的公式可能是根据外科医生的技术定制的。不同队列之间的差异不可避免;不过,鉴于我们的样本量较大,我们预计结果是可靠的。我们有理由得出结论,现有公式并不能准确反映切除权重,因此用于手术规划并不可靠。
{"title":"Resection Weight Formulas for Reduction Mammoplasty: A Systematic Review and Regression Analysis.","authors":"Nisha Gupta, Christian X Lava, Sami Ferdousian, Karen R Li, Jenna C Bekeny, Kenneth L Fan","doi":"10.1097/SAP.0000000000004114","DOIUrl":"10.1097/SAP.0000000000004114","url":null,"abstract":"<p><strong>Purpose: </strong>Estimating resection weight for patients undergoing reduction mammoplasty (RM) informs surgical planning and outcomes. Existing formulas have limitations that make insurance coverage and accurate surgical planning challenging. We identified the most commonly used scales to evaluate their accuracy in estimating resection weight by applying them to a database of patients to compare calculated and actual resection weights.</p><p><strong>Methods: </strong>A database search was conducted using combinations of relevant terms. A regression analysis was conducted using formulas with strong R2 values (0.72-0.93) on a cohort of 1128 RM patients at a single institution.</p><p><strong>Results: </strong>A total of 570 articles were identified. Fourteen manuscripts (n = 2232 patients [3320 breasts]) were ultimately included for review. Data on incisional patterns, pedicle supply, and breast measurements, such as sternal notch to nipple distance (n = 8 [57.1%]) or nipple to inframammary fold distance (n = 5 [35.7%]), were recorded. R2 values in our cohort (>500 g, n = 891; <500 g, n = 237) were calculated via regression analyses with five formulas: Appel (0.391 vs 0.146), Boukovalas (0.3552 vs 0.043), Descamps (0.391 vs 0.238), Eder (0.328 vs 0.114), and Kocak (0.3283 vs R2 indeterminate).</p><p><strong>Conclusions: </strong>Our analysis suggests that formulas reporting strong R2 values may have resulted from tailoring to surgeons' technique. Variation between cohorts is inevitable; however, we expect reliable results given our large sample. It is reasonable to conclude that existing formulas are not accurate representations of resection weights and thus are unreliable for surgical planning.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"93 5","pages":"643-648"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Assessment of External Nasal Valve Efficiency After Le Fort I Surgery: Erratum. 勒堡 I 期手术后鼻腔外瓣膜效率的评估:勘误。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-10-07 DOI: 10.1097/SAP.0000000000004140
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Annals of Plastic Surgery
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