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Predicting the Timing and Cause of Microvascular Free Flap Failure: An Australian Study of 1569 Free Flaps. 预测微血管游离皮瓣失败的时间和原因:澳大利亚对1569个游离皮瓣的研究。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-10-01 Epub Date: 2024-07-15 DOI: 10.1097/SAP.0000000000004063
Yash Gupta, Elias Moisidis, Fred Clarke, Roger Haddad, Vlad Illie, James Southwell-Keely

Background: The aim of the study is to assess the possible predictors of microvascular free flap failure and determine the critical postoperative timing of flap failure, thereby minimizing this adverse outcome.

Methods: This is a retrospective single-institutional review of 1569 free flap operations. All free flaps with outcome status recorded were analyzed for possible predictors in the development of microvascular compromise. Compromised cases were then analyzed for differences in time to compromise and time to theater takeback between salvaged versus failed free flaps.

Results: Of the assessable 1569 free flaps, 31 developed microvascular compromise (2.0%); the salvage rate was 20.0%, and overall failure rate was 1.5%. Osteocutaneous free flaps in head and neck had increased risk of developing free flap failure compared to other flaps (odds ratio = 3.8, 95% confidence interval: 1.2-12.7). Among breast patients, previous radiotherapy had a significant association with flap failure ( P < 0.001). Free flap salvage rates dropped from 38.5% to 7.7% for compromises detected after 24 hours ( P = 0.160), and from 57.1% to 11.1% for free flaps taken back to theater greater than 3 hours after compromise detection ( P = 0.032).

Conclusions: Delays in compromise detection and flap takeback to theater resulted in reduced salvage rates, with the critical timing of takeback being under 3 hours. Standardized flap monitoring protocols and incorporation of newer technologies could see faster detection and improved salvage rates. Additional care is required when reconstructing: osteocutaneous head and neck free flaps and previously irradiated breast patients.

背景:该研究旨在评估微血管游离皮瓣失败的可能预测因素,并确定术后皮瓣失败的关键时机,从而将这一不良后果降至最低:本研究旨在评估微血管游离皮瓣失败的可能预测因素,并确定皮瓣失败的术后关键时机,从而最大限度地减少这一不良后果:这是一项对 1569 例游离皮瓣手术进行的单机构回顾性研究。对所有有结果记录的游离皮瓣进行了分析,以找出微血管受损的可能预测因素。然后,对受损病例进行分析,以确定挽救的游离皮瓣与失败的游离皮瓣在受损时间和术后恢复时间上的差异:结果:在可评估的 1569 个游离皮瓣中,31 个出现微血管损伤(2.0%);挽救率为 20.0%,总体失败率为 1.5%。与其他皮瓣相比,头颈部的骨皮游离皮瓣发生游离皮瓣失败的风险更高(几率比=3.8,95%置信区间:1.2-12.7)。在乳腺患者中,既往接受过放疗与皮瓣失败有显著关联(P < 0.001)。在24小时后发现皮瓣受损的患者中,游离皮瓣的挽救率从38.5%降至7.7%(P = 0.160),在发现皮瓣受损超过3小时后将游离皮瓣带回手术室的患者中,游离皮瓣的挽救率从57.1%降至11.1%(P = 0.032):结论:皮瓣受损检测和皮瓣送回手术室的延迟会降低抢救率,而送回的关键时间应在3小时以内。标准化的皮瓣监测方案和新技术的应用可以加快检测速度,提高抢救率。在重建骨皮头颈部游离皮瓣和曾接受过放射治疗的乳房患者时需要格外小心。
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引用次数: 0
Modified Intravascular Stent for Microvascular Suture in a Rat Superficial Femoral Artery. 用于大鼠股浅动脉微血管缝合的改良型血管内支架
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-09-19 DOI: 10.1097/SAP.0000000000004098
Kosuke Maeda, Taku Suzuki, Yohei Masugi, Osahiko Tsuji, Takuji Iwamoto, Masaya Nakamura

Background: Intravascular stent (IVaS) is sometimes used for suturing small vessels, but removing the stent after suturing is difficult. To overcome this problem, we developed an IVaS that integrates a stent and a manipulating string. This study aimed to investigate the usefulness of the modified IVaS (M-IVaS) by comparing it with conventional sutures (CS) and conventional IVaS (C-IVaS).

Methods: Forty-five superficial femoral arteries from rats were resected and sutured. The rats were randomly divided into the following 3 groups: CS, M-IVaS, and C-IVaS, with 15 rats per group. Patency rate, operating time, and ultrasonographic blood flow dynamics were examined immediately after suturing. Patency tests, ultrasonographic evaluations, and histological investigations were performed 1 week (n = 5), 2 weeks (n = 5), and 6 weeks (n = 5) after surgery.

Results: The 3 groups showed vessel patency in all cases immediately after suturing and at 1 week, 2 weeks, and 6 weeks after surgery. The mean operative time was 22.6 minutes for the CS group, 21.5 minutes for the M-IVaS group, and 25.9 minutes for the C-IVaS group. There were no significant differences in peak flow velocity and stenosis rate among the 3 groups as evaluated by ultrasonography. Histopathological evaluation revealed a similar recovery process of endothelial cells and no damage to the vascular wall.

Conclusion: The surgical time using M-IVaS was significantly shorter compared to that using C-IVaS. The M-IVaS reduced the inconvenience of C-IVaS removal. M-IVaS showed the same effectiveness as did the CS in terms of patency rate, operating time, ultrasonographic blood flow dynamics, and histological evaluation. M-IVaS can be used in the field of microsurgery.

背景:血管内支架(IVaS)有时用于缝合小血管,但缝合后取出支架很困难。为了克服这一问题,我们开发了一种将支架和操纵绳整合在一起的 IVaS。本研究旨在通过与传统缝合器(CS)和传统IVAS(C-IVAS)的比较,研究改良型IVAS(M-IVAS)的实用性:方法:切除并缝合 45 只大鼠的股浅动脉。大鼠随机分为以下 3 组:CS、M-IVaS 和 C-IVaS,每组 15 只。缝合后立即检查通畅率、手术时间和超声血流动力学。术后 1 周(5 只)、2 周(5 只)和 6 周(5 只)分别进行了通畅测试、超声波评估和组织学检查:3 组病例在缝合后立即以及术后 1 周、2 周和 6 周均显示血管通畅。CS 组的平均手术时间为 22.6 分钟,M-IVaS 组为 21.5 分钟,C-IVaS 组为 25.9 分钟。通过超声波检查评估,三组的峰值流速和狭窄率无明显差异。组织病理学评估显示,内皮细胞的恢复过程相似,血管壁无损伤:结论:使用 M-IVaS 的手术时间明显短于使用 C-IVaS 的手术时间。结论:使用 M-IVaS 的手术时间明显短于使用 C-IVaS 的手术时间。在通畅率、手术时间、超声血流动力学和组织学评估方面,M-IVaS显示出与CS相同的有效性。M-IVaS 可用于显微外科领域。
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引用次数: 0
The Impact of Area Deprivation Index, Geography, and Mechanism on Incidence of Ballistic Injury to the Upper Extremity. 地区贫困指数、地理位置和机制对上肢弹道伤害发生率的影响。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2024-09-16 DOI: 10.1097/sap.0000000000004108
Danielle J Brown,Amelia C Van Handel,Kevin G Shim,Rachael M Payne,Damini Tandon,David Chi,Adam G Evans,Mitchell A Pet
INTRODUCTIONThis study investigates the intersection of ballistic injuries, geography, and Area Deprivation Index (ADI). We hypothesized that both ADI and geography are correlated with incidence of upper extremity ballistic injuries. Further, we characterize and compare 2 distinct upper extremity gunshot injury populations presenting to our institution: those sustaining violent ballistic injuries and those who suffer an accidental, self-inflicted injury. Our purpose is to evaluate the impact of geography and ADI on the pattern of upper extremity gunshot injuries in Illinois and Missouri.MATERIALS AND METHODSThis was a retrospective review of adult patients sustaining ballistic injury to the upper extremity at a single urban level I trauma center over 10 years (n = 797). Seven hundred thirty patients had home addresses in Illinois or Missouri; these addresses were geocoded and included for analysis. Mechanism of injury was self-reported. ADI was measured from the 2019 Neighborhood Atlas, in which deprivation increases from 1 to 100. Comparisons between groups were conducted with unpaired t tests, Fisher exact test, or χ2 testing, where appropriate.RESULTSAddresses constituted 259 unique census tracts, and the average number of upper extremity gunshot wound incidents per tract was 3, with a maximum of 22; 15.4% of census block tracts made up almost half (48.4%) of the total ballistic injuries in the study period; 97.7% of violent injuries occurred in Urban areas, as compared with only 60% of accidental injuries (P < 0.05). ADI and incidence of upper extremity ballistic injury were positively correlated. ADI varied significantly between patients sustaining violent (median, 94; mean, 86.1) versus accidental self-inflicted (median, 79; mean, 70.9) injuries (P < 0.05). Fifty percent of violent injuries in our data set occurred in block groups from the 2 most deprived quintiles.CONCLUSIONSUpper extremity gunshot wounds in general are concentrated in census blocks with high ADI. Violent injuries in particular are more likely to occur in urban areas with high ADI, whereas patients with accidental, self-inflicted injuries are more geographically and socioeconomically diverse. These differing populations require unique approaches to reduce incidence and morbidity.
简介:本研究调查了弹道伤害、地理位置和地区贫困指数(ADI)之间的相互关系。我们假设 ADI 和地理位置都与上肢弹道损伤的发生率相关。此外,我们还描述并比较了两种不同的上肢枪伤人群:暴力弹道伤害人群和意外自伤人群。我们的目的是评估地理位置和 ADI 对伊利诺伊州和密苏里州上肢枪伤模式的影响。材料和方法这是一项回顾性研究,研究对象是 10 年间在一个城市一级创伤中心接受上肢弹道伤的成年患者(n = 797)。730 名患者的家庭住址位于伊利诺伊州或密苏里州;这些住址已进行地理编码并纳入分析。受伤机制为自我报告。ADI是根据2019年邻里地图集(Neighborhood Atlas)测算的,其中贫困程度从1到100依次递增。组间比较酌情采用非配对 t 检验、费舍尔精确检验或 χ2 检验。结果地址构成了 259 个独特的人口普查区,每个人口普查区的上肢枪伤事件平均为 3 起,最多为 22 起;15.4% 的人口普查区占研究期间弹道伤害总数的近一半(48.4%);97.7% 的暴力伤害发生在城市地区,而意外伤害仅占 60%(P < 0.05)。ADI与上肢弹道损伤的发生率呈正相关。暴力伤害(中位数,94;平均值,86.1)与意外自伤(中位数,79;平均值,70.9)患者的 ADI 有明显差异(P < 0.05)。在我们的数据集中,50% 的暴力伤害发生在 2 个最贫困五分位数的街区。特别是暴力伤害更有可能发生在 ADI 高的城市地区,而意外自伤患者在地理和社会经济方面更加多样化。这些不同的人群需要采取独特的方法来降低发病率和发病率。
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引用次数: 0
Immediate Breast Reconstruction After Mastectomy for Cancer Among US Military Health System Beneficiaries. 美国军队医疗系统受益者因癌症切除乳房后立即进行乳房重建。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2024-09-11 DOI: 10.1097/sap.0000000000004077
Justin P Fox,Kerry P Latham,Sarah Darmon,Yvonne L Eaglehouse,Julie A Bytnar,Craig D Shriver,Kangmin Zhu
BACKGROUNDIn the Military Health System (MHS), women with breast cancer may undergo surgical treatment in military hospitals (direct care) or in the civilian setting via the insurance benefit (private sector care). We conducted this study to determine immediate breast reconstruction rates among women undergoing mastectomy for cancer in the MHS by setting of care.METHODSUsing the linked Department of Defense's Central Cancer Registry and MHS Data Repository, the Department of Defense's medical claims database, we identified adult women who underwent mastectomy for breast cancer from 1998 to 2014. Patients were then subgrouped by setting of care (direct vs private sector care). The primary outcome was the rate and type of immediate breast reconstruction. Regression models were constructed to determine factors associated with receipt of immediate breast reconstruction.RESULTSThe final sample included 3251 women who underwent mastectomy for cancer in the direct (67.0%) or private sector care (32.6%) settings. The overall rate of immediate breast reconstruction was 29.9% with an upward trend noted throughout the study (P < 0.001). Overall, implant-based reconstruction (81.4%) was more common than tissue-based reconstruction (18.6%). Compared with direct care, the immediate breast reconstruction rate was significantly higher in the private sector care setting (49.3% vs 20.5%, P < 0.001) despite accounting for differences in clinical characteristics (adjusted odds ratio = 4.51, 95% confidence interval [3.72-5.46]).CONCLUSIONSImmediate breast reconstruction in the direct care setting lags that in the civilian community during the study time period. Further research is needed to ascertain current immediate reconstruction rates and understand factors contributing to any differences in rates between care settings.
背景在军事医疗系统(MHS)中,患有乳腺癌的女性可以在军队医院(直接医疗)或通过保险福利在平民环境(私人医疗)中接受手术治疗。我们开展了这项研究,以确定在军事医疗系统中接受乳房切除术的女性中,根据护理环境立即进行乳房重建的比例。方法通过链接国防部中央癌症登记处和国防部医疗索赔数据库 MHS 数据库,我们确定了 1998 年至 2014 年期间因乳腺癌接受乳房切除术的成年女性。然后按照医疗机构(直接医疗机构与私人医疗机构)对患者进行分组。主要结果是即时乳房重建的比例和类型。结果最终样本包括 3251 名在直接医疗机构(67.0%)或私立医疗机构(32.6%)接受乳腺癌切除术的女性。即刻乳房重建的总体比例为 29.9%,在整个研究过程中呈上升趋势(P < 0.001)。总体而言,植入物重建(81.4%)比组织重建(18.6%)更常见。与直接护理相比,尽管考虑到临床特征的差异(调整后的几率比=4.51,95% 置信区间[3.72-5.46]),私立医疗机构的即时乳房再造率明显更高(49.3% vs 20.5%,P <0.001)。需要进一步研究以确定当前的即刻乳房再造率,并了解造成不同护理环境下即刻乳房再造率差异的因素。
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引用次数: 0
Classification of Microtia With Unusable Remnant Ear and Techniques in the First Stage of Two-Stage Auricular Reconstruction. 无法使用残耳的小耳症分类和两阶段耳廓重建术第一阶段的技术。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2024-09-04 DOI: 10.1097/sap.0000000000004103
Bei He,Bingqing Wang,Qingguo Zhang
BACKGROUNDThe remnant ear is a very important material in auricular reconstruction surgery; its dimension, position, and shape determine how it is used. However, the local conditions of microtia patients are complex and variable. Situations may be encountered where a series of abnormal remnant ears cannot be utilized in clinical practice. Currently, there are no literature that elaborates on this type of microtia and provides systematic treatment methods. The purpose of this article is to systematically classify them and optimize the two-stage method auricular reconstruction, to provide an effective surgical method for these patients.METHODSBased on the size, shape, and relative position of the residual ears, the unusable remnant ears were classified into three types: tiny size, abnormal shape, and relative position anomaly (over 1-cm higher than the contralateral earlobe). Fifty-three microtia patients with unusable remnant ear (54 ears) who underwent two-stage auricular reconstruction from August 2020 to August 2023 were reviewed. All patients had experienced earlobe reconstruction by using autologous rib cartilage during the first stage of surgery. Aesthetic assessments were evaluated from the naturalness of the earlobe reconstructed with autologous rib cartilage and the connection with the overall framework. The data on any complications that occurred during the follow-up period and patient satisfaction were collected.RESULTSAmong all patients, 31 had tiny size, 14 had abnormal shape, and 8 had excessively high positions. Patients were followed up for an average period of 9.2 months (6 to 12 months). No complex complications such as infection, skin necrosis, or cartilage exposure occurred. Fifty patients (94.3%) achieved excellent or good aesthetic outcomes. Fifty-one patients (96.2%) were satisfied with the reconstruction outcomes.CONCLUSIONSAn accurate assessment of the residual ear preoperatively is essential. Reconstructing and splicing the earlobe with autologous rib cartilage in cases where the residual ear cannot be utilized compensate for the defect that the soft tissue cannot provide the earlobe flap. This is an effective surgical method for the ear reconstruction in such patients.
背景残耳是耳廓重建手术中非常重要的材料,其尺寸、位置和形状决定了如何使用它。然而,小耳症患者的局部情况复杂多变。在临床实践中,可能会遇到无法使用一系列异常残耳的情况。目前,还没有文献对这类小耳症进行详细阐述,并提供系统的治疗方法。方法根据残耳的大小、形状和相对位置,将无法使用的残耳分为三种类型:极小、形状异常和相对位置异常(比对侧耳垂高出 1 厘米以上)。研究人员回顾了在 2020 年 8 月至 2023 年 8 月期间接受两阶段耳廓重建手术的 53 名小耳症患者(54 耳)。所有患者在第一阶段手术中都使用了自体肋软骨进行耳垂重建。美学评估从使用自体肋软骨重建的耳垂的自然程度以及与整体框架的连接情况进行评估。结果在所有患者中,31 例患者的耳垂过小,14 例患者的耳垂形状异常,8 例患者的耳垂位置过高。患者的随访时间平均为 9.2 个月(6 至 12 个月)。没有出现感染、皮肤坏死或软骨外露等复杂并发症。50名患者(94.3%)获得了极佳或良好的美学效果。结论术前对残耳进行准确评估至关重要。在无法利用残耳的情况下,用自体肋软骨重建和拼接耳垂,可以弥补软组织无法提供耳垂瓣的缺陷。对于此类患者,这是一种有效的耳部重建手术方法。
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引用次数: 0
Hospital Transfers for Digit Replants as Cost Saving and Safe While Access to Replantation Procedures Remains Limited. 转院进行指骨移植既省钱又安全,而移植手术的可及性仍然有限。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2024-09-04 DOI: 10.1097/sap.0000000000004099
Sacha C Hauc,Jacqueline M Ihnat,Kevin Hu,Neil Parikh,Jean Carlo Rivera,Michael Alperovich
BACKGROUNDFinger replantation outcomes are influenced both by injury characteristics and by hospital and patient factors, such as hospital type/location and patient gender or insurance. Finger replantation success rates have been shown to be higher at hospitals with higher volumes of finger replants. This study examines the hospital and patient factors that influence hospital transfer and successful replantation in patients experiencing traumatic finger amputation.METHODSA total of 5219 patients were identified in the 2008-2015 National Inpatient Sample (NIS) as having experienced traumatic finger amputation with attempted replantation. Hospital transfer and replant outcomes were compared with variables such as patient demographics and hospital characteristics using χ2 tests, t tests, ANOVA, and logistic regression.RESULTSTraumatic digit amputation patients were most likely to be transferred to medium or large hospitals in urban areas. Hospital transfer was 1.5 times more likely in White patients than Black or Hispanic patients and 1.6 times more likely in middle income quartile patients than the top income quartile. Postreplant amputation was more likely in patients in the lower three income quartiles, on Medicare, of older age, or with more chronic conditions. Hospital transfer was not associated with changes in the probability of requiring amputation after replantation but was associated with a decreased cost of $5000.CONCLUSIONSHospital transfers for finger replants are safe with respect to replant failure rates and cost-effective, saving $5000 per procedure. Gaps in equitable access to care remain, warranting further study to improve health equity.
背景手指再植术的结果既受损伤特征的影响,也受医院和患者因素的影响,如医院类型/地点、患者性别或保险等。有研究表明,手指再植成功率较高的医院的手指再植成功率更高。本研究探讨了影响外伤性断指患者转院和再植成功的医院和患者因素。方法在 2008-2015 年全国住院患者样本(NIS)中,共确定了 5219 名曾经历外伤性断指并尝试再植的患者。采用χ2检验、t检验、方差分析和逻辑回归法将转院和再植结果与患者人口统计学和医院特征等变量进行比较。白人患者转院的可能性是黑人或西班牙裔患者的1.5倍,中等收入四分位数患者转院的可能性是最高收入四分位数患者的1.6倍。在收入较低的三个四分位数、享受医疗保险、年龄较大或慢性病较多的患者中,移植后截肢的可能性更大。转院与再植后需要截肢的概率变化无关,但与减少5000美元的费用有关。结论:就再植失败率而言,手指再植的转院是安全的,而且具有成本效益,每次手术可节省5000美元。在公平获得医疗服务方面仍存在差距,需要进一步研究以提高医疗公平性。
{"title":"Hospital Transfers for Digit Replants as Cost Saving and Safe While Access to Replantation Procedures Remains Limited.","authors":"Sacha C Hauc,Jacqueline M Ihnat,Kevin Hu,Neil Parikh,Jean Carlo Rivera,Michael Alperovich","doi":"10.1097/sap.0000000000004099","DOIUrl":"https://doi.org/10.1097/sap.0000000000004099","url":null,"abstract":"BACKGROUNDFinger replantation outcomes are influenced both by injury characteristics and by hospital and patient factors, such as hospital type/location and patient gender or insurance. Finger replantation success rates have been shown to be higher at hospitals with higher volumes of finger replants. This study examines the hospital and patient factors that influence hospital transfer and successful replantation in patients experiencing traumatic finger amputation.METHODSA total of 5219 patients were identified in the 2008-2015 National Inpatient Sample (NIS) as having experienced traumatic finger amputation with attempted replantation. Hospital transfer and replant outcomes were compared with variables such as patient demographics and hospital characteristics using χ2 tests, t tests, ANOVA, and logistic regression.RESULTSTraumatic digit amputation patients were most likely to be transferred to medium or large hospitals in urban areas. Hospital transfer was 1.5 times more likely in White patients than Black or Hispanic patients and 1.6 times more likely in middle income quartile patients than the top income quartile. Postreplant amputation was more likely in patients in the lower three income quartiles, on Medicare, of older age, or with more chronic conditions. Hospital transfer was not associated with changes in the probability of requiring amputation after replantation but was associated with a decreased cost of $5000.CONCLUSIONSHospital transfers for finger replants are safe with respect to replant failure rates and cost-effective, saving $5000 per procedure. Gaps in equitable access to care remain, warranting further study to improve health equity.","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142250509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thirty-Day Complication Rates After Gender-Affirming Bottom Surgery: An Analysis of the NSQIP Database From 2010 to 2020. 性别确认底部手术后三十天的并发症发生率:2010 年至 2020 年 NSQIP 数据库分析。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-09-04 DOI: 10.1097/SAP.0000000000004069
Jennifer Goldman, Anna Hu, Adam Hammer, Yagiz Matthew Akiska, Cindy Gombaut, Bharat Ranganath, Jerry Chao

Purpose: Gender-affirming bottom surgeries (GABS) play a central role in treating gender dysphoria to improve quality of life for transgender and nonbinary (TGNB) patients. However, there exists limited data on operative risks and outcomes for patient populations undergoing GABS. The goal of this study is to identify sociodemographic and clinical risk factors for determining 30-day postoperative complications in patients undergoing GABS.

Methods: The ACS-NSQIP database from 2010 to 2020 was used to identify patients undergoing gender affirmation surgery (GAS) using Current Procedural Terminology (CPT) codes included in transfeminine and transmasculine bottom surgery. IBS-SPSS software was used to perform a multivariate analysis to determine risk factors for increased 30-day postoperative complications including unplanned reoperation and readmission rates.

Results: A total of 1809 GABS were performed in the NSQIP database from 2010 to 2020. There was an upward trend in GABS procedures throughout the years, with 2017 having the most GABS (n = 629). Transmasculine patients with a BMI of 29 and over were at a greater risk for wound complications (P < 0.05). Diabetic transfeminine patients were also at a greater risk for wound complications (P < 0.05).

Conclusions: This study identified that several sociodemographic and clinical risk factors, such as BMI and diabetes mellitus type 2, had increased postoperative complications for patients undergoing gender-affirming bottom surgeries. Wound care management and patient education are essential in GABS to prevent long-term complications. Physician awareness of risk factors and social determinants of health can help prevent and improve postoperative care education and patient compliance.

目的:性别确认底部手术(GABS)在治疗性别障碍以提高变性和非二元性(TGNB)患者的生活质量方面发挥着核心作用。然而,有关接受 GABS 手术的患者群体的手术风险和结果的数据非常有限。本研究的目的是确定社会人口学和临床风险因素,以确定接受 GABS 患者术后 30 天的并发症:方法:利用 2010 年至 2020 年的 ACS-NSQIP 数据库,使用当前程序术语(CPT)代码识别接受性别确认手术(GAS)的患者,这些代码包括跨女性和跨男性化下体手术。使用 IBS-SPSS 软件进行多变量分析,以确定术后 30 天并发症增加的风险因素,包括非计划再手术和再入院率:从2010年到2020年,NSQIP数据库中共进行了1809例GABS手术。GABS手术数量呈逐年上升趋势,其中2017年的GABS手术数量最多(n = 629)。体重指数(BMI)在29及以上的跨性别患者出现伤口并发症的风险更高(P < 0.05)。糖尿病经阴道患者出现伤口并发症的风险也更高(P < 0.05):本研究发现,一些社会人口学和临床风险因素(如体重指数和 2 型糖尿病)会增加接受性别确认下体手术患者的术后并发症。要预防长期并发症,伤口护理管理和患者教育对 GABS 至关重要。医生对风险因素和健康的社会决定因素的认识有助于预防和改善术后护理教育及患者的依从性。
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引用次数: 0
GLP-1 Agonists: A Practical Overview for Plastic and Reconstructive Surgeons. GLP-1 激动剂:整形外科医生实用概览》。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2024-09-04 DOI: 10.1097/sap.0000000000004089
Eloise W Stanton,Artur Manasyan,Rakhi Banerjee,Kurt Hong,Emma Koesters,David A Daar
BACKGROUNDGlucagon-like peptide-1 (GLP-1) agonists, such as exenatide, liraglutide, dulaglutide, semaglutide, and tirzepatide, effectively manage type 2 diabetes by promoting insulin release, suppressing glucagon secretion, and enhancing glucose metabolism. They also aid weight reduction and cardiovascular health, potentially broadening their therapeutic scope. In plastic surgery, they hold promise for perioperative weight management and glycemic control, potentially impacting surgical outcomes.METHODSA comprehensive review was conducted to assess GLP-1 agonists' utilization in plastic surgery. We analyzed relevant studies, meta-analyses, and trials to evaluate their benefits and limitations across surgical contexts, focusing on weight reduction, glycemic control, cardiovascular risk factors, and potential complications.RESULTSStudies demonstrate GLP-1 agonists' versatility, spanning weight management, cardiovascular health, neurological disorders, and metabolic dysfunction-associated liver diseases. Comparative analyses highlight variations in glycemic control, weight loss, and cardiometabolic risk. Meta-analyses reveal significant reductions in hemoglobin A1C levels, especially with high-dose semaglutide (2 mg) and tirzepatide (15 mg). However, increased dosing may lead to gastrointestinal side effects and serious complications like pancreatitis and bowel obstruction. Notably, GLP-1 agonists' efficacy in weight reduction and glycemic control may impact perioperative management in plastic surgery, potentially expanding surgical candidacy for procedures like autologous flap-based breast reconstruction and influencing outcomes related to lymphedema. Concerns persist regarding venous thromboembolism and delayed gastric emptying, necessitating further investigation into bleeding and aspiration risk with anesthesia.CONCLUSIONSGLP-1 agonists offer advantages in perioperative weight management and glycemic control in plastic surgery patients. They may broaden surgical candidacy and mitigate lymphedema risk but require careful consideration of complications, particularly perioperative aspiration risk. Future research should focus on their specific impacts on surgical outcomes to optimize their integration into perioperative protocols effectively. Despite challenges, GLP-1 agonists promise to enhance surgical outcomes and patient care in plastic surgery.
背景胰高血糖素样肽-1(GLP-1)激动剂(如艾塞那肽、利拉鲁肽、度拉鲁肽、塞马鲁肽和替扎帕肽)通过促进胰岛素释放、抑制胰高血糖素分泌和加强葡萄糖代谢来有效控制 2 型糖尿病。它们还有助于减轻体重和心血管健康,有可能扩大其治疗范围。在整形外科中,它们有望用于围手术期体重管理和血糖控制,从而对手术效果产生潜在影响。方法我们进行了一项全面的综述,以评估 GLP-1 激动剂在整形外科中的应用。我们对相关研究、荟萃分析和试验进行了分析,以评估其在不同手术环境下的益处和局限性,重点关注减轻体重、血糖控制、心血管风险因素和潜在并发症。研究结果表明,GLP-1 促效剂用途广泛,可用于体重管理、心血管健康、神经系统疾病和代谢功能障碍相关肝病。对比分析凸显了血糖控制、体重减轻和心脏代谢风险方面的差异。荟萃分析显示,血红蛋白 A1C 水平显著降低,尤其是大剂量的塞马鲁肽(2 毫克)和替泽帕肽(15 毫克)。然而,增加剂量可能会导致胃肠道副作用以及胰腺炎和肠梗阻等严重并发症。值得注意的是,GLP-1 激动剂在减轻体重和控制血糖方面的疗效可能会影响整形外科的围手术期管理,有可能扩大自体皮瓣乳房重建等手术的候选范围,并影响与淋巴水肿相关的治疗效果。对静脉血栓栓塞和胃排空延迟的担忧依然存在,因此有必要进一步调查麻醉中的出血和吸入风险。GLP-1受体激动剂可扩大手术范围并减轻淋巴水肿风险,但需要仔细考虑并发症,尤其是围手术期的吸入风险。未来的研究应重点关注它们对手术效果的具体影响,以便将其有效地融入围手术期方案中。尽管存在挑战,但 GLP-1 激动剂有望提高整形外科的手术效果和患者护理。
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引用次数: 0
Choke Anastomosis: A Key Element Acting as a Shunt Converter Between Adjacent Angiosomes. 窒息吻合:作为相邻血管小体之间分流转换器的关键因素。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-09-04 DOI: 10.1097/SAP.0000000000004079
Zilong Cao, Hu Jiao, Cheng Gan, Tiran Zhang, Jia Tian, Rui Li, Qiang Yue, Ningbei Yin, Liqiang Liu

Background: Choke anastomosis is commonly recognized as a resistance factor that detrimentally affects the hemodynamics of the skin flap; however, its additional potential physiological roles in normal skin function are currently not fully understood.

Methods: Ten cadaveric forehead flap specimens pedicled with unilateral STAs were perfused with lead oxide-gelatin mixture, and then dissected into 3 layers, including the super temporal fascia-frontalis-galea aponeurotica layer, the subcutaneous adipose tissue layer, and the "super-thin flap" layer. The forehead flap and stratified specimens underwent molybdenum target x-ray and subsequent transparent processing to effectively visualize the microscopic spatial architecture of arterial vessels across all levels.

Results: Based on the different anastomoses near the midline area of the flap, 2 types of arterial perfusion were identified: choke anastomosis type (8/10) and true anastomosis type (2/10). The former formed multiple choke anastomoses near the midline. In the "super-thin flap" layer, arterial perfusion density on the ipsilateral side was significantly higher compared to that on the contralateral side. The arterioles on the ipsilateral side exhibited a dense and uninterrupted distribution, whereas those on the contralateral side appeared sparse and dispersed. The latter exhibited an alternative perfusion pattern; the bilateral arterial vessels were connected with 3 to 5 true anastomoses near the midline. Furthermore, the microscopic architecture confirmed a uniform distribution of arterioles that remained continuous from ipsilateral to contralateral sides in the "super-thin flap" layer.

Conclusion: This study demonstrated that choke anastomosis not only impairs blood perfusion in the adjacent angiosomes but also acts as a shunt converter to impact the blood supply of distal skin flaps at different levels through the "trans-territory diversion phenomenon." This results in necrosis of the superficial dermis while preserving survival of the deep subcutaneous adipose tissue.

背景:窒息吻合通常被认为是一种阻力因素,会对皮瓣的血液动力学产生不利影响;然而,其在正常皮肤功能中的其他潜在生理作用目前尚不完全清楚:方法:用氧化铅-明胶混合物灌注 10 个前额皮瓣标本,然后将其解剖成 3 层,包括颞上筋膜-额肌-睑肌腱层、皮下脂肪组织层和 "超薄皮瓣 "层。前额皮瓣和分层标本经过钼靶X射线和随后的透明处理,可有效观察到各层动脉血管的微观空间结构:结果:根据皮瓣中线附近的不同吻合情况,确定了两种类型的动脉灌注:扼流吻合型(8/10)和真吻合型(2/10)。前者在中线附近形成多处窒息吻合。在 "超薄皮瓣 "层中,同侧的动脉灌注密度明显高于对侧。同侧的动脉血管分布密集且不间断,而对侧的动脉血管分布稀疏且分散。后者表现出另一种灌注模式;双侧动脉血管在中线附近有 3 至 5 个真正的吻合口相连。此外,显微镜结构证实,"超薄皮瓣 "层中的动脉血管分布均匀,从同侧到对侧保持连续:本研究表明,扼流吻合术不仅会影响相邻血管小体的血液灌注,而且还会通过 "跨区分流现象 "充当分流转换器,影响不同层次远端皮瓣的血液供应。这导致表层真皮坏死,而深层皮下脂肪组织得以存活。
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引用次数: 0
Valleix's Sign. Valleix 的标志。
IF 1.4 4区 医学 Q3 SURGERY Pub Date : 2024-09-01 Epub Date: 2024-05-31 DOI: 10.1097/SAP.0000000000003968
Andreas Gohritz, A Lee Dellon

Abstract: Some patients present with clinical symptoms of localized tenderness and pain associated with a specific peripheral nerve, such as the ulnar nerve at the elbow or the sciatic nerve, which has been called, although rarely, "Valleix point" or "Valleix phenomenon". The purpose of this article was to translate and research the 719-page book "Traité des névralgies ou affections douloureuses des nerfs" dated 1841, dedicated solely to nerve pain (neuralgia), written by the French physician François Louis Isidore Valleix (1807-1855). He may have been the first person to observe and describe this phenomenon of localized pain, but he was probably also the first to describe distal nerve radiation, which he called "élancement" or lancinating, or stabbing. He described the phenomenon of a nerve producing pain at points along its course that we now understand to be sites of compression, clearly describing cubital and fibular tunnel syndromes, which he called neuralgias. He also described some rarer sites of compression, such as supraorbital and occipital neuralgia, notalgia paresthetica, and ACNES, but he did not describe the most common site of compression today, the median nerve at the wrist. Valleix's descriptions are clear and precede the classic 1915 reports of Hoffmann's and Tinel's signs by 74 years.

摘要:有些患者会出现与特定周围神经(如肘部尺神经或坐骨神经)相关的局部触痛和疼痛的临床症状,这种症状被称为 "Valleix点 "或 "Valleix现象",但很少见。本文旨在翻译和研究法国医生弗朗索瓦-路易斯-伊西多尔-瓦莱克斯(François Louis Isidore Valleix,1807-1855 年)于 1841 年专门针对神经痛(神经痛)撰写的 719 页书籍《Traité des névralgies ou affections douloureuses des nerfs》。他可能是第一个观察和描述这种局部疼痛现象的人,但他可能也是第一个描述远端神经放射的人,他称之为 "élancement "或 "lancinating "或 "刺痛"。他描述了神经沿其走向产生疼痛的现象,我们现在理解为压迫部位,他清楚地描述了肘臼隧道综合征和腓骨隧道综合征,他称之为神经痛。他还描述了一些罕见的压迫部位,如眶上神经痛和枕神经痛、痛觉神经痛和 ACNES,但他没有描述当今最常见的压迫部位,即手腕处的正中神经。Valleix 的描述非常清晰,比 1915 年霍夫曼征和 Tinel 征的经典报告早 74 年。
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引用次数: 0
期刊
Annals of Plastic Surgery
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