Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E3282742022
C. H. A. Lest, A. Vaandrager
{"title":"Mechanism of cell-mediated mineralization","authors":"C. H. A. Lest, A. Vaandrager","doi":"10.1097/BCO.0B013E3282742022","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282742022","url":null,"abstract":"","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"434-443"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282742022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E3282BE8F35
L. Tosi
{"title":"Mother was right","authors":"L. Tosi","doi":"10.1097/BCO.0B013E3282BE8F35","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282BE8F35","url":null,"abstract":"","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"479"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282BE8F35","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E3282E6F3DE
T. Kirsch
{"title":"Physiological and pathological mineralization: a complex multifactorial process","authors":"T. Kirsch","doi":"10.1097/BCO.0B013E3282E6F3DE","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282E6F3DE","url":null,"abstract":"","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"41 1","pages":"425-427"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282E6F3DE","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E3282B97118
P. Dimitri, N. Bishop
Rickets is a disease that has plagued communities for centuries. Once thought of as a disease that was left behind in the industrial revolution of the nineteenth century, nutritional rickets is re-emerging as a problem in Western Europe and the US. Reduction in vitamin D and calcium intake in children's diets along with migration of culturally vulnerable groups to more temperate climates have increased, predisposing large populations to vitamin D deficiency and rickets. Recent evidence suggests that vitamin D deficiency during pregnancy may have both an immediate and longer-term deleterious effect on children. Focus on hypophosphataemic rickets has identified FGF23 as the phosphaturic factor central to renal phosphate loss. Mutations in the dentin matrix protein-1 gene have been implicated in autosomal recessive hypophosphataemic rickets. Rickets is the most common form of metabolic bone disease worldwide. Measures such as adequate sunlight exposure and dietary supplementation are simple but effective in reducing rickets. It is important to target culturally vulnerable groups and pregnant women. Preterm babies form a specific population that is particularly vulnerable to the metabolic consequences of calcium and phosphate deficiency, requiring early intervention.
{"title":"Rickets: new insights into a re-emerging problem","authors":"P. Dimitri, N. Bishop","doi":"10.1097/BCO.0B013E3282B97118","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282B97118","url":null,"abstract":"Rickets is a disease that has plagued communities for centuries. Once thought of as a disease that was left behind in the industrial revolution of the nineteenth century, nutritional rickets is re-emerging as a problem in Western Europe and the US. Reduction in vitamin D and calcium intake in children's diets along with migration of culturally vulnerable groups to more temperate climates have increased, predisposing large populations to vitamin D deficiency and rickets. \u0000Recent evidence suggests that vitamin D deficiency during pregnancy may have both an immediate and longer-term deleterious effect on children. Focus on hypophosphataemic rickets has identified FGF23 as the phosphaturic factor central to renal phosphate loss. Mutations in the dentin matrix protein-1 gene have been implicated in autosomal recessive hypophosphataemic rickets. \u0000Rickets is the most common form of metabolic bone disease worldwide. Measures such as adequate sunlight exposure and dietary supplementation are simple but effective in reducing rickets. It is important to target culturally vulnerable groups and pregnant women. Preterm babies form a specific population that is particularly vulnerable to the metabolic consequences of calcium and phosphate deficiency, requiring early intervention.","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"486-493"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282B97118","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E328285DFFC
R. Zaka, C. Williams
{"title":"The inorganic phosphate/inorganic pyrophosphate axis in the mineralization of cartilage and bone","authors":"R. Zaka, C. Williams","doi":"10.1097/BCO.0B013E328285DFFC","DOIUrl":"https://doi.org/10.1097/BCO.0B013E328285DFFC","url":null,"abstract":"","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"454-459"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E328285DFFC","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E3282A9C162
E. Seeman
{"title":"Bone??s material and structural strength","authors":"E. Seeman","doi":"10.1097/BCO.0B013E3282A9C162","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282A9C162","url":null,"abstract":"","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"494-498"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282A9C162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E3282BA54C4
Naina Sinha, R. Bockman
{"title":"The impact of bariatric surgery on bone metabolism","authors":"Naina Sinha, R. Bockman","doi":"10.1097/BCO.0B013E3282BA54C4","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282BA54C4","url":null,"abstract":"","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"505-509"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282BA54C4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E328285DFE8
C. Thouverey, F. Bleicher, J. Bandorowicz-Pikula
{"title":"Extracellular ATP and its effects on physiological and pathological mineralization","authors":"C. Thouverey, F. Bleicher, J. Bandorowicz-Pikula","doi":"10.1097/BCO.0B013E328285DFE8","DOIUrl":"https://doi.org/10.1097/BCO.0B013E328285DFE8","url":null,"abstract":"","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"460-466"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E328285DFE8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E32825E1D84
A. Rosenthal
Purpose of reviewMineralization of the extracellular matrix is crucial for the development and maintenance of healthy bones and teeth, but also contributes to the pathologic calcification seen in atherosclerosis, osteoarthritis, and nephrolithiasis. Extracellular matrix participates in both normal a
{"title":"The role of noncollagenous proteins in mineralization","authors":"A. Rosenthal","doi":"10.1097/BCO.0B013E32825E1D84","DOIUrl":"https://doi.org/10.1097/BCO.0B013E32825E1D84","url":null,"abstract":"Purpose of reviewMineralization of the extracellular matrix is crucial for the development and maintenance of healthy bones and teeth, but also contributes to the pathologic calcification seen in atherosclerosis, osteoarthritis, and nephrolithiasis. Extracellular matrix participates in both normal a","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"449-453"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E32825E1D84","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-09-01DOI: 10.1097/BCO.0B013E3282AB992F
J. Glowacki
Purpose of review Recent evidence confirms the widespread occurrence of vitamin D deficiency and inadequacy in the general population, especially in patients with fractures and in populations at risk for osteoporotic fractures. Recent findings Limited exposure to sunlight and dietary sources, especially among the elderly, has contributed to the reemergence of musculoskeletal problems attributable to hypovitaminosis D. Overarching themes in the recent literature include the alarming evidence that recommendations for ensuring skeletal health are not being utilized, and the evidence indicating that daily intakes for vitamin D need to be higher than the current national recommendations. Summary Clinicians and healthcare advocacy organizations have called attention to the need for revision of the recommended daily intake of vitamin D on the basis of the amount required to achieve a serum 25-hydroxyvitamin D level of at least 32 ng/ml (80 nmol/l), the serum concentration that is needed to optimize absorption of dietary calcium, suppress excess secretion of parathyroid hormone, and reduce fracture risk. Evidence indicates that to sustain adequate serum levels of 25-hydroxyvitamin D, a daily oral dose of vitamin D3 should be in the order of 1000–2000 IU/day.
{"title":"Vitamin D inadequacy in 2007: what it is and how to manage it","authors":"J. Glowacki","doi":"10.1097/BCO.0B013E3282AB992F","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282AB992F","url":null,"abstract":"Purpose of review Recent evidence confirms the widespread occurrence of vitamin D deficiency and inadequacy in the general population, especially in patients with fractures and in populations at risk for osteoporotic fractures. Recent findings Limited exposure to sunlight and dietary sources, especially among the elderly, has contributed to the reemergence of musculoskeletal problems attributable to hypovitaminosis D. Overarching themes in the recent literature include the alarming evidence that recommendations for ensuring skeletal health are not being utilized, and the evidence indicating that daily intakes for vitamin D need to be higher than the current national recommendations. Summary Clinicians and healthcare advocacy organizations have called attention to the need for revision of the recommended daily intake of vitamin D on the basis of the amount required to achieve a serum 25-hydroxyvitamin D level of at least 32 ng/ml (80 nmol/l), the serum concentration that is needed to optimize absorption of dietary calcium, suppress excess secretion of parathyroid hormone, and reduce fracture risk. Evidence indicates that to sustain adequate serum levels of 25-hydroxyvitamin D, a daily oral dose of vitamin D3 should be in the order of 1000–2000 IU/day.","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"480-485"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282AB992F","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：