Archives of Environmental & Occupational Health最新文献

Identifying the source of lead is a key measure in the management of childhood lead poisoning. In cases with multiple potential sources or with unusual circumstances, this identification can be complex. By comparing the lead isotopic ratios (IRs) between the potential sources and the blood sample from the patient, it is possible to identify which source caused the poisoning. We report here the case of a 13-years-old girl, screened for lead poisoning as she was known to eat paint chips from two walls in her apartment. Her blood lead level was 395 µg/L, and the environmental investigation came back negative. X-ray fluorescence found lead concentration in paints to be below the regulatory threshold of 1 mg/cm². As there was no other potential source of lead exposure in this case, a comparative analysis of the IRs of lead between the child's blood and two presumed sources (bathroom and kitchen paints) was performed. This analysis confirmed the source of lead intoxication to be the paints in the apartment, mostly from the bathroom wall.

Blood cells are used as the most sensitive marker to determine the effects and intensity of ionizing radiation. This descriptive study aimed to evaluate the effect of radiation exposure on hematological parameters in healthcare workers who were exposed to radiation in a university hospital between May and June 2021. A total of 339 participants were included, of which 169 (49.9%) were radiation workers and 170 (50.1%) were in the control group. A decrease was observed in white blood cell and neutrophil counts in those exposed to ionizing radiation for less than 10 years; however, white blood cell, neutrophil, hemoglobin levels decreased, and red cell distribution width (RDW) levels increased in those exposed to ionizing radiation for 10 years or more (p < 0.005). A statistically significant increase was observed in the RDW and lymphocyte levels as the years of work experience in the profession increase in the group exposed to IR. The findings indicate that the effect of low-dose ionizing radiation on the hematopoietic system is related to the frequency and duration of the dose. Hematological parameters can be sensitive biomarkers of low-dose ionizing radiation; possible disturbances in the hematopoietic system can be recognized before the onset of symptoms, and necessary precautions can be taken promptly.

Thiacloprid (TH), one of the most widely used pesticides in the world, might cause toxic effects like DNA damage in humans and animals due to their frequent use. Accordingly, this study investigated TH's potential DNA-damaging effects on zebrafish liver via alkaline comet assay. Two treatment groups of ten zebrafish each were exposed to TH at two different concentrations, 1.64 and 0.82 mg/L, for 21 days and compared with an untreated control group. After exposure, the fishes' liver tissues were excised, and an alkaline comet assay was performed. Two slides per sample and 50 cells per slide were assessed with a visual evaluation program. The average DNA Damage values of the control, 0.82 mg/L TH, and 1.64 mg/L TH groups were 4.37 ± 5.12, 8.51 ± 8.54, and 9.30 ± 9.99, respectively. Both TH treatment groups had statistically significantly more DNA damage than the control group (p < 0.001). When comparing the TH treatment groups alone, the 1.64 mg/L dose group featured greater damage than the 0.82 mg/L dose group (p < 0.05). TH therefore causes significant DNA damage to the liver in a dose-dependent manner, revealing it to be a genotoxic agent that should be further investigated.

The most frequent adverse physical health effect among World Trade Center Health Program (WTCHP) members is chronic rhinosinusitis (CRS), with some evidence supporting its association with the exposures to dust, gases, and toxicants. We selected the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICARS-RS-2021) as a comprehensive evidence-based guide on best practices for CRS diagnosis and treatment for the WTCHP.

This study aimed to investigate the coronavirus disease 2019 (COVID-19) infection prevention and control (IPC) practices and related factors among paramedics. We selected 249 paramedics using convenience sampling from three areas in Korea. Data on the demographics, infection-related characteristics, awareness, and practice of IPC were collected using self-reported questionnaires. The mean IPC practice score was 4.47 ± 0.54. The compliance with IPC practices was relatively high among those with a disease history (B = 0.194, p = 0.045) and who were aware of the safety management standard guidelines. Provision of sufficient protective equipment and infection prevention monitoring were associated with higher IPC practice scores. Education for increasing awareness of the recent IPC guidelines and the allocation of personal protective equipment would be helpful in improving the practice.