Construction activities have long been recognized as a pertinent source of PM2.5 though limited information exists regarding chemical characteristics of aerosols generated during building demolition/construction. A comprehensive investigation was carried out to assess the physical (SEM analysis) and chemical (ICP MS analysis) properties of PM2.5 in a building demolition and construction site and compared with background. Average concentrations of PM2.5 at both the sites exceeded the National Ambient Air Quality Standards (NAAQS). Overall trend of the total metal concentrations of PM2.5 followed the order of (Na, Ca, Al, Mg, Fe, Zn) > (Ti, Sr, Cd, Ba, Pb, V, Cr, Mn, Co, Ni, Cu) in both the sites. Sr, Ba, Mg, Zn, Ti, Cd, Al, Cr, Fe, Co, Mn, V, Ni, Ca, and Zn showed a ∼1.3-3.0 fold increase, and Pb showed the highest increase of almost >3.5 times when compared to the background concentrations. Health risk estimates based on the bio-available concentration of metals indicated that hazard quotient (HQ) values for non-carcinogenic metals were within the prescribed limit (HQ ≤ 1). However, the excess lifetime cancer risk (ELCR) for the carcinogenic metals Pb, Ni, Cd, and Cr(VI) were higher than the guideline limits of USEPA.
The knowledge, attitude and practices of employees and employers toward reducing sedentary behavior (SB) and improving physical activity (PA) at Indian workplaces remain unclear. A bespoke questionnaire assessing barriers and facilitators of occupational SB and PA practices as informed by the theoretical framework and behavioral change wheel model was adapted. Two hundred and three white-collar workers (both employees and managers) from eight corporate sectors were inquired about the SB, and PA practices at workplaces. The dichotomous variables of barriers and facilitators were analyzed by nonparametric tests. Excessive sitters had good knowledge (>75%), good attitude (>85%) but poor workplace SB and PA practice (>90%). Workplace SB, or PA practices differed between employers and employees. Low practice of workplace PA or SB interventions may be due to lack of workplace policies for SB interventions.
Nutritional status plays a major role in determining the possible adverse health outcomes due to pesticide toxicity. The objective of the present study was to assess the organophosphorus pesticide residue levels among farm women (FW) (24-45years) and farm children (FC) (9-12 and 13-15years) belonging to the Rangareddy district (Telangana, India) along with their micronutrient status, inhibition of acetylcholinesterase activity, and oxidative stress levels. Residues of Chlorpyrifos, Diazinon, Malathion, Monocrotophos and Phosalone were found in the serum samples of FW and FC along with significantly low levels of vitamins and minerals. Inhibition of AChE activity was observed in FW and FC and altered oxidative stress parameters among FW. Correlation studies have found significant associations between the pesticide residues, micronutrients and antioxidant enzymes. The study suggests an association between pesticide exposure coupled with micronutrient deficiency, induced AChE inhibition, and oxidative stress.
Epidemiological studies suggest suppression of the lymphocytes function through cholinergic stimulation due to organophosphorus pesticide exposure. The study aimed to assess the alteration in the levels of immune cell phenotypes among farm women (FW) and farm children (FC) who were occupationally exposed to pesticides and age/gender-matched control subjects belonging to Rangareddy district (Telangana, India). A total of 129 FW, 129 FC and 268 age/gender-matched controls were recruited. Blood samples were collected from the selected subjects to estimate the levels of nine organophosphorus pesticide residues and CD (CD3+, CD4+, CD8+, CD16+ and CD19+) cell markers using LC-MS/MS and flow cytometry, respectively. Independent t-test analysis was conducted to compare the immune cell phenotypes between exposed and control groups. Spearman's rank correlation test was further carried out to identify any possible correlation between the pesticide residues and CD markers. The mean percentage for CD4+, CD8+ and CD16+ was found to be significantly low, while for CD19 + itwas significantly high in the FW as compared to the CW group (p < 0.01). Further, the residues of chlorpyrifos and monocrotophos among FW were found to be significantly correlating with the mean percentages of CD19+ and CD8+ markers, respectively. The cell marker subsets of CD4+ and CD8+ were significantly low in FC children 9-12 years and 13-15 years age groups, respectively (p < 0.05). Also, these levels were significantly correlating with the residues of malathion and monocrotophos. The present study could indicate an alteration in the lymphocytes' subpopulations, which may thereby infer the toxicity in the first phase assessment of immunotoxicity. Therefore, further studies may be conducted to understand the suspected pesticides' mechanism along with various other factors in causing immune suppression coupled with nutritional and other related disorders.
Due to the high prevalence of noise and vibration exposure in most industries, this study aimed to investigate the effects of simultaneous exposure to noise and vibration on sex hormone levels and fertility capacity in rats, as well as the protective effects of the hydroalcoholic extract of cinnamon. In this experimental study, 64 adult male rats were randomly divided into 8 groups, control, noise (N), cinnamon (C), noise + cinnamon (NC), vibration (V), vibration + cinnamon (VC), noise + vibration (NV) and groups Noise + Vibration + Cinnamon (NVC). Groups C, NC, VC and NVC received a 75 mg/kg dose of cinnamon extract by gavage. The rats of groups N and NC, V and VC and NV and NVC were each exposed to noise at 100 dB (700-5700 Hz), vibration acceleration of 1 m/s2 rms (frequency range of 4-8 Hz), and simultaneously exposed to vibration and noise for 8 hours continuously every night (23:00-7:00) for 50 consecutive nights. Next, a blood sample was taken from the lateral tail vein and the levels of LH, FSH and testosterone were measured with ELISA kits. Each male rat was caged with 3 female rats for one week. The pregnant rats were kept until all of the rat pups were born. Then the fertility capacity, the total number of births, the live births and the birth weight of the rat pups were analyzed with the software SPSS. In the N and NV groups, compared to the control group, a significant decrease in LH and testosterone levels, the number of births and the birth weight was observed (p < 0.05). A significant decrease in testosterone levels, number of births and birth weight was observed in Group V compared to the control group (p < 0.05). In addition, significant increases in LH, FSH and testosterone levels and in birth weight were observed in group C compared to the control group (p < 0.05). Significant increases in FSH and testosterone levels, birth weight, and the number of births were noted in the NVC group compared to the NV group (p < 0.05). Based on the results of this study, cinnamon extract could alleviate the destructive effects of noise and vibration (both individually and in combination) on levels of sex hormones (LH, FSH, and testosterone), the number of births, and birth weight.
This case report describes a 61-year-old male who sought treatment for sudden symptoms of dry cough, chest pain and severe dyspnea. On admission, the patient had hypoxemia and predominantly medullary infiltrate that we could observe on his imaging exams. After hospital discharge, he presented two similar episodes, with clinical and radiological improvement with oxygen therapy alone. He denied exposure to birds, mold or chemical agents. However, the patient noticed the onset of symptoms soon after drinking chimarrão. Given the compatible clinical, radiological and laboratory history, the diagnosis of hypersensitivity pneumonitis was performed. The patient was instructed by the medical team not to consume the drink anymore, remaining asymptomatic for more than two years.
No published noise exposure assessment of occupational health and safety (OHS) consultants exists. An assessment was performed to quantify the noise level of OHS consultants while they were on site at a client's facility. OHS consultants wore a dosimeter set to A-weighting, slow response, 60 s log interval and a criterion level of 85dBA with a 3 dB exchange rate. Both the projected time-weighted average (TWA) and projected dose were recorded. Of the 32 noise assessments collected, three had projected TWAs that exceeded the occupational exposure limit of 85 dBA. Nearly 75% of the projected TWA measurements were equal or greater than the Action Level of 80 dBA. According to best practices, occupational noise levels greater than 80 dBA present a risk for noise-induced hearing loss and, therefore, a hearing loss prevention program should be implemented.
This work is a cross-sectional comparative study conducted on 528 residents in the slum and non-slum areas of Pokhara, Nepal. Of the total number of respondents, 90.2% in the slums and 63.3% in the non-slums indicated the existence of a main source of noise, and 80.7% in the slums and 66.0% in the non-slums replied that they had been highly annoyed by noise. The indoor noise levels measured for 24 h were higher in slums than in non-slums, ranging from 59 to 78 dBA and from 51 to 69 dBA, respectively. The Mann-Whitney U test showed a significantly poorer status of slum dwellers in four health domains. Logistic regression analysis identified that living in a slum was a significant predictor (OR, 2.35; 95% CI, 1.35-4.09) of a low level of health. Meanwhile, a high level of noise annoyance was a good determinant (OR, 6.71; 95% CI, 3.13-14.36) of low quality of life among slum dwellers revealing a distinguishing negative effect of the high level of noise annoyance in the slum areas.
Rising worldwide demand and consumption of fossil fuels have elevated wealth creation, improved undesirable impacts on climatic change from emission of greenhouse gases, and endangered communal health. In developing nations, biomass wastes, which include but are not limited to agricultural residues, are generated in huge quantities yearly. During the disposal of biomass, incomplete combustion causes people to get exposed to elevated indoor concentrations on health-damaging pollutants including particulate matter and carbon monoxide. Inefficient usage or disposed biomass wastes may cause toxic impacts on higher levels of pollution, the consequent degeneration of public health and ecological contamination. It is possible to convert these wastes into energy-efficient briquettes through densification. In this research work, the combustion characteristics were identified from biomass briquettes which were produced from Onion Peels (OP), Tamarind Shells (TS) and Cassava Starch. OP-TS were mixed sequentially and conversely with different proportions. From the total weight of biomass, 10% of cassava starch was added and briquettes were produced under 200 kN pressure from the compressed hydraulic system within the dwell time of 60 seconds. The proximate characteristics such as the presence of water content, amount of fixed carbon, ash and volatile matter were determined by using the standard procedures of the American Society for Testing and Materials (ASTM). The ultimate parameter, which is inclusive of Carbon (C), Hydrogen (H) and Oxygen (O) were diagnosed in all produced biomass briquettes and calorific values were identified for all the produced biomass briquettes as well. OP-TS have better fuel properties in comparison with pine, cotton stalk (CS), wood sawdust (WS), municipal solid waste (MSW) and cotton straw biomass briquettes (CSB). Therefore, the produced biomass briquettes could bring substantial environmental and socio-economic benefits to rural communities and are potentially worthy fuels derived from agricultural wastes.
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