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Bovine Colostrum for Veterinary and Human Health Applications: A Critical Review. 牛初乳在兽医和人类健康方面的应用综述。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2023-03-27 DOI: 10.1146/annurev-food-060721-014650
Kevin Linehan, R Paul Ross, Catherine Stanton

Bovine colostrum harbors a diverse array of bioactive components suitable for the development of functional foods, nutraceuticals, and pharmaceuticals with veterinary and human health applications. Bovine colostrum has a strong safety profile with applications across all age groups for health promotion and the amelioration of a variety of disease states. Increased worldwide milk production and novel processing technologies have resulted in substantial growth of the market for colostrum-based products. This review provides a synopsis of the bioactive components in bovine colostrum, the processing techniques used to produce high-value colostrum-based products, and recent studies utilizing bovine colostrum for veterinary and human health.

牛初乳含有多种生物活性成分,适用于开发具有兽医和人类健康应用的功能性食品、营养保健品和药品。牛初乳具有很强的安全性,适用于所有年龄组的健康促进和改善各种疾病状态。全球牛奶产量的增加和新的加工技术导致了初乳产品市场的大幅增长。本文综述了牛初乳中的生物活性成分、生产高价值牛初乳产品的加工技术以及利用牛初乳促进兽医和人类健康的最新研究进展。
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引用次数: 1
Nondigestible Functional Oligosaccharides: Enzymatic Production and Food Applications for Intestinal Health. 不可消化功能性低聚糖:酶促生产及其在肠道健康中的食品应用。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2023-03-27 DOI: 10.1146/annurev-food-052720-114503
Shaoqing Yang, Chenxuan Wu, Qiaojuan Yan, Xiuting Li, Zhengqiang Jiang

Nondigestible functional oligosaccharides are of particular interest in recent years because of their unique prebiotic activities, technological characteristics, and physiological effects. Among different types of strategies for the production of nondigestible functional oligosaccharides, enzymatic methods are preferred owing to the predictability and controllability of the structure and composition of the reaction products. Nondigestible functional oligosaccharides have been proved to show excellent prebiotic effects as well as other benefits to intestinal health. They have exhibited great application potential as functional food ingredients for various food products with improved quality and physicochemical characteristics. This article reviews the research progress on the enzymatic production of several typical nondigestible functional oligosaccharides in the food industry, including galacto-oligosaccharides, xylo-oligosaccharides, manno-oligosaccharides, chito-oligosaccharides, and human milk oligosaccharides. Moreover, their physicochemical properties and prebiotic activities are discussed as well as their contributions to intestinal health and applications in foods.

近年来,不可消化功能性低聚糖因其独特的益生元活性、工艺特性和生理作用而受到广泛关注。在不同类型的生产不可消化功能性低聚糖的策略中,酶促方法是首选的,因为反应产物的结构和组成具有可预测性和可控制性。不可消化的功能性低聚糖已被证明具有良好的益生元效应以及对肠道健康的其他益处。它们作为功能性食品配料,在提高食品质量和理化特性方面具有很大的应用潜力。本文综述了食品工业中几种典型的难消化功能性低聚糖的酶促生产研究进展,包括半乳糖低聚糖、低聚木糖、甘露寡糖、壳寡糖和人乳低聚糖。此外,还讨论了它们的理化性质和益生元活性,以及它们对肠道健康的贡献和在食品中的应用。
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引用次数: 5
Bioinformatic Approaches for Characterizing Molecular Structure and Function of Food Proteins. 表征食品蛋白质分子结构和功能的生物信息学方法。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2023-03-27 DOI: 10.1146/annurev-food-060721-022222
Harrison Helmick, Anika Jain, Genki Terashi, Andrea Liceaga, Arun K Bhunia, Daisuke Kihara, Jozef L Kokini

Structural bioinformatics analyzes protein structural models with the goal of uncovering molecular drivers of food functionality. This field aims to develop tools that can rapidly extract relevant information from protein databases as well as organize this information for researchers interested in studying protein functionality. Food bioinformaticians take advantage of millions of protein amino acid sequences and structures contained within these databases, extracting features such as surface hydrophobicity that are then used to model functionality, including solubility, thermostability, and emulsification. This work is aided by a protein structure-function relationship framework, in which bioinformatic properties are linked to physicochemical experimentation. Strong bioinformatic correlations exist for protein secondary structure, electrostatic potential, and surface hydrophobicity. Modeling changes in protein structures through molecular mechanics is an increasingly accessible field that will continue to propel food science research.

结构生物信息学分析蛋白质结构模型,目的是揭示食物功能的分子驱动因素。该领域旨在开发能够从蛋白质数据库中快速提取相关信息的工具,并为对研究蛋白质功能感兴趣的研究人员组织这些信息。食品生物信息学家利用这些数据库中包含的数百万蛋白质氨基酸序列和结构,提取表面疏水性等特征,然后用于模拟功能,包括溶解度,热稳定性和乳化性。这项工作得益于蛋白质结构-功能关系框架,其中生物信息学特性与物理化学实验相关联。蛋白质二级结构、静电势和表面疏水性之间存在很强的生物信息学相关性。通过分子力学模拟蛋白质结构的变化是一个越来越容易进入的领域,将继续推动食品科学研究。
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引用次数: 2
Mild Fractionation for More Sustainable Food Ingredients. 温和的分馏为更可持续的食品配料。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2023-03-27 DOI: 10.1146/annurev-food-060721-024052
A Lie-Piang, J Yang, M A I Schutyser, C V Nikiforidis, R M Boom

With the rising problems of food shortages, energy costs, and raw materials, the food industry must reduce its environmental impact. We present an overview of more resource-efficient processes to produce food ingredients, describing their environmental impact and the functional properties obtained. Extensive wet processing yields high purities but also has the highest environmental impact, mainly due to heating for protein precipitation and dehydration. Milder wet alternatives exclude, for example, low pH-driven separation and are based on salt precipitation or water only. Drying steps are omitted during dry fractionation using air classification or electrostatic separation. Benefits of milder methods are enhanced functional properties. Therefore, fractionation and formulation should be focused on the desired functionality instead of purity. Environmental impact is also strongly reduced by milder refining. Antinutritional factors and off-flavors remain challenges in more mildly produced ingredients. The benefits of less refining motivate the increasing trend toward mildly refined ingredients.

随着食品短缺、能源成本和原材料问题的日益严重,食品工业必须减少对环境的影响。我们提出了更资源高效的过程,以生产食品成分的概述,描述他们的环境影响和获得的功能特性。广泛的湿法加工产生高纯度,但也有最大的环境影响,主要是由于加热蛋白质沉淀和脱水。例如,较温和的湿替代方法排除了低ph驱动的分离,并且仅基于盐沉淀或水。在使用空气分级或静电分离的干燥分馏过程中,干燥步骤被省略。温和方法的好处是增强了功能特性。因此,分馏和配方应侧重于所需的功能而不是纯度。温和的精炼也大大减少了对环境的影响。抗营养因素和异味仍然是温和生产原料的挑战。较少精炼的好处促使了对温和精制成分的日益增长的趋势。
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引用次数: 5
The Almond (Prunus dulcis): Chemical Properties, Utilization, and Valorization of Coproducts. 杏仁(Prunus dulcis):化学性质、利用和副产品的增值。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2022-03-25 Epub Date: 2021-12-22 DOI: 10.1146/annurev-food-052720-111942
Haruka Tomishima, Kathleen Luo, Alyson E Mitchell

Almonds (Prunus dulcis) are one of the most consumed tree-nuts worldwide, with commercial production in arid environments such as California, Spain, and Australia. The high consumption of almonds is partly due to their versatile usage in products such as gluten-free flour and dairy alternatives as well as them being a source of protein in vegetarian diets. They contain high concentrations of health-promoting compounds such as Vitamin E and have demonstrated benefits for reducing the risk of cardiovascular disease and improving vascular health. In addition, almonds are the least allergenic tree nut and contain minute quantities of cyanogenic glycosides. Production has increased significantly in the past two decades with 3.12 billion pounds of kernel meat produced in California alone in 2020 (USDA 2021), leading to a new emphasis on the valorization of the coproducts (e.g., hulls, shells, skins, and blanch water). This article presents a review of the chemical composition of almond kernels (e.g., macro and micronutrients, phenolic compounds, cyanogenic glycosides, and allergens) and the current research exploring the valorization of almond coproducts.

杏仁(Prunus dulcis)是世界上消费最多的坚果之一,在加利福尼亚、西班牙和澳大利亚等干旱环境中有商业生产。杏仁的高消费量部分是由于它们在产品中的广泛用途,如无麸质面粉和乳制品替代品,以及它们是素食饮食中蛋白质的来源。它们含有高浓度的促进健康的化合物,如维生素E,并已被证明对降低心血管疾病的风险和改善血管健康有益。此外,杏仁是最不容易引起过敏的树坚果,含有微量的氰苷。在过去的二十年里,产量显著增加,仅在2020年,加州就生产了31.2亿磅仁肉(美国农业部2021年),这导致了对副产品(如壳、壳、皮和焯水)价值的新重视。本文综述了杏仁核的化学成分(如宏量营养素和微量营养素、酚类化合物、氰苷和过敏原)以及杏仁副产物的增值研究进展。
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引用次数: 7
Chemical Stability of Proteins in Foods: Oxidation and the Maillard Reaction. 食品中蛋白质的化学稳定性:氧化和美拉德反应。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2022-03-25 Epub Date: 2021-12-23 DOI: 10.1146/annurev-food-052720-104513
Mahesha M Poojary, Marianne N Lund

Protein is a major nutrient present in foods along with carbohydrates and lipids. Food proteins undergo a wide range of modifications during food production, processing, and storage. In this review, we discuss two major reactions, oxidation and the Maillard reaction, involved in chemical modifications of food proteins. Protein oxidation in foods is initiated by metal-, enzyme-, or light-induced processes. Food protein oxidation results in the loss of thiol groups and the formation of protein carbonyls and specific oxidation products of cysteine, tyrosine, tryptophan, phenylalanine, and methionine residues, such as disulfides, dityrosine, kynurenine, m-tyrosine, and methionine sulfoxide. The Maillard reaction involves the reaction of nucleophilic amino acid residues with reducing sugars, which yields numerous heterogeneous compounds such as α-dicarbonyls, furans, Strecker aldehydes, advanced glycation end-products, and melanoidins. Both protein oxidation and the Maillard reaction result in the loss of essential amino acids but may positively or negatively impact food structure and flavor.

蛋白质与碳水化合物和脂质一样是食物中的主要营养物质。食品蛋白质在食品生产、加工和储存过程中经历了广泛的修饰。本文综述了食品蛋白化学修饰的两种主要反应:氧化反应和美拉德反应。食物中的蛋白质氧化是由金属、酶或光诱导的过程引起的。食物蛋白质氧化导致巯基的损失和蛋白质羰基的形成,以及半胱氨酸、酪氨酸、色氨酸、苯丙氨酸和蛋氨酸残基的特定氧化产物,如二硫化物、二酪氨酸、犬尿氨酸、间酪氨酸和蛋氨酸亚砜。美拉德反应涉及亲核氨基酸残基与还原糖的反应,产生许多异相化合物,如α-二羰基、呋喃、Strecker醛、晚期糖基化终产物和类黑素。蛋白质氧化和美拉德反应都导致必需氨基酸的损失,但可能对食品结构和风味产生积极或消极的影响。
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引用次数: 17
Current Perspectives on Food Oral Processing. 食品口腔加工的最新进展。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2022-03-25 DOI: 10.1146/annurev-food-052720-103054
Yue He, Xinmiao Wang, Jianshe Chen

Food oral processing (FOP) is a fast-emerging research area in the food science discipline. Since its first introduction about a decade ago, a large amount of literature has been published in this area, forming new frontiers and leading to new research opportunities. This review aims to summarize FOP research progress from current perspectives. Food texture, food flavor (aroma and taste), bolus swallowing, and eating behavior are covered in this review. The discussion of each topic is organized into three parts: a short background introduction, reflections on current research findings and achievements, and future directions and implications on food design. Physical, physiological, and psychological principles are the main concerns of discussion for each topic. The last part of the review shares views on the research challenges and outlooks of future FOP research. It is hoped that the review not only helps readers comprehend what has been achieved in the past decade but also, more importantly, identify where the knowledge gaps are and in which direction the FOP research will go.

食品口腔加工是食品科学学科中一个新兴的研究领域。自大约十年前首次引入以来,该领域已发表了大量文献,形成了新的前沿,并带来了新的研究机会。本文旨在从目前的角度对FOP的研究进展进行综述。食物的质地,食物的味道(香气和味道),丸剂吞咽,和进食行为涵盖在这篇综述。每个主题的讨论分为三个部分:简短的背景介绍,对当前研究成果和成果的反思,以及未来食品设计的方向和意义。物理、生理和心理原理是每个主题讨论的主要关注点。最后,对未来FOP研究面临的挑战和前景进行了展望。希望这篇综述不仅能帮助读者了解过去十年取得的成就,而且更重要的是,确定知识差距在哪里以及FOP研究的方向。
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引用次数: 8
New Insights into Cheese Microstructure. 对奶酪微观结构的新认识。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2022-03-25 DOI: 10.1146/annurev-food-032519-051812
Lydia Ong, Xu Li, Adabelle Ong, Sally L Gras

Microscopy is often used to assist the development of cheese products, but manufacturers can benefit from a much broader application of these techniques to assess structure formation during processing and structural changes during storage. Microscopy can be used to benchmark processes, optimize process variables, and identify critical control points for process control. Microscopy can also assist the reverse engineering of desired product properties and help troubleshoot production problems to improve cheese quality. This approach can be extended using quantitative analysis, which enables further comparisons between structural features and functional measures used within industry, such as cheese meltability, shreddability, and stretchability, potentially allowing prediction and control of these properties. This review covers advances in the analysis of cheese microstructure, including new techniques, and outlines how these can be applied to understand and improve cheese manufacture.

显微镜通常用于辅助奶酪产品的开发,但制造商可以从这些技术的更广泛应用中受益,以评估加工过程中的结构形成和储存过程中的结构变化。显微镜可用于基准过程,优化过程变量,并确定过程控制的关键控制点。显微镜还可以协助所需产品特性的逆向工程,并帮助解决生产问题,以提高奶酪质量。这种方法可以通过定量分析进行扩展,可以进一步比较工业中使用的结构特征和功能指标,如奶酪的可熔化性、可碎裂性和可拉伸性,从而有可能预测和控制这些特性。这篇综述涵盖了奶酪微观结构分析的进展,包括新技术,并概述了如何应用这些技术来理解和改进奶酪生产。
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引用次数: 4
The Influence of the Western Diet on Microbiota and Gastrointestinal Immunity. 西方饮食对微生物群和胃肠道免疫的影响。
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2022-03-25 Epub Date: 2022-01-06 DOI: 10.1146/annurev-food-052720-011032
Vanessa Las Heras, Silvia Melgar, John MacSharry, Cormac G M Gahan

Diet exerts a major influence upon host immune function and the gastrointestinal microbiota. Although components of the human diet (including carbohydrates, fats, and proteins) are essential sources of nutrition for the host, they also influence immune function directly through interaction with innate and cell-mediated immune regulatory mechanisms. Regulation of the microbiota community structure also provides a mechanism by which food components influence host immune regulatory processes. Here, we consider the complex interplay between components of the modern (Western) diet, the microbiota, and host immunity in the context of obesity and metabolic disease, inflammatory bowel disease, and infection.

饮食对宿主免疫功能和胃肠道微生物群有重要影响。虽然人类饮食的成分(包括碳水化合物、脂肪和蛋白质)是宿主必需的营养来源,但它们也通过与先天和细胞介导的免疫调节机制的相互作用直接影响免疫功能。微生物群落结构的调节也为食物成分影响宿主免疫调节过程提供了一种机制。在这里,我们考虑了现代(西方)饮食、微生物群和宿主免疫在肥胖和代谢性疾病、炎症性肠病和感染背景下的复杂相互作用。
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引用次数: 5
Bioactive Components in Traditional Foods Aimed at Health Promotion: A Route to Novel Mechanistic Insights and Lead Molecules? 旨在促进健康的传统食品中的生物活性成分:新的机制见解和铅分子的途径?
IF 12.4 1区 农林科学 Q1 Agricultural and Biological Sciences Pub Date : 2022-03-25 Epub Date: 2022-01-18 DOI: 10.1146/annurev-food-052720-092845
Renger F Witkamp

Traditional foods and diets can provide health benefits beyond their nutrient composition because of the presence of bioactive compounds. In various traditional healthcare systems, diet-based approaches have always played an important role, which has often survived until today. Therefore, investigating traditional foods aimed at health promotion could render not only novel bioactive substances but also mechanistic insights. However, compared to pharmacologically focused research on natural products, investigating such nutrition-based interventions is even more complicated owing to interacting compounds, less potent and relatively subtle effects, the food matrix, and variations in composition and intake. At the same time, technical advances in 'omics' technologies, cheminformatics, and big data analysis create new opportunities, further strengthened by increasing insights into the biology of health and homeostatic resilience. These are to be combined with state-of-the-art ethnobotanical research, which is key to obtaining reliable and reproducible data. Unfortunately, socioeconomic developments and climate change threaten traditional use and knowledge as well as biodiversity.

由于存在生物活性化合物,传统食品和饮食可以提供超出其营养成分的健康益处。在各种传统的医疗保健系统中,以饮食为基础的方法一直发挥着重要作用,直到今天仍然存在。因此,研究旨在促进健康的传统食品不仅可以提供新的生物活性物质,还可以提供机制见解。然而,与以药理学为重点的天然产品研究相比,由于相互作用的化合物、效力较弱且相对微妙的影响、食物基质以及成分和摄入量的变化,调查这种基于营养的干预措施更加复杂。与此同时,“组学”技术、化学信息学和大数据分析方面的技术进步创造了新的机会,而对健康生物学和体内平衡恢复力的深入了解进一步加强了这些机会。这些将与最先进的民族植物学研究相结合,这是获得可靠和可重复数据的关键。不幸的是,社会经济发展和气候变化威胁着传统的利用和知识以及生物多样性。
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引用次数: 3
期刊
Annual review of food science and technology
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