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Current Practices and Perspectives on Ambulatory Thyroid Surgery in Italy: A Survey by the Società Italiana Chirurgia Endoscopica e Nuove Tecnologie (SICE) in Preparation for the DECORATED Trial. 意大利门诊甲状腺手术的当前实践和前景:意大利外科内镜和新技术协会(SICE)在准备装饰试验中的调查。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-18 DOI: 10.62713/aic.4015
Francesco Maria Carrano, Andrea Casaril, Sara Manella, Eleonora Rapanotti, Francesco D'Angelo, Gianfranco Silecchia, Gabriele Anania, Diego Cuccurullo, Vincenzo Pilone, Giuseppe Currò

Aim: The Coronavirus disease 19 (COVID-19) pandemic has significantly impacted elective thyroid surgery, leading to a reduction in procedures and an increase in waiting lists. In response, thyroidectomy is increasingly being performed as an outpatient procedure worldwide, with comparable outcomes and readmission rates to those of overnight stays after surgery in high-volume centers. However, in Italy, ambulatory thyroid surgery is rarely practiced because of concerns about the safety and efficacy of such approaches. This specific timeframe represents a unique opportunity to capture a snapshot of the Italian thyroid surgery practices and drive a practice change while providing a practical solution to the huge backlog of procedures.

Methods: A survey was conducted among Italian surgical centers to assess their practices and preferences regarding various aspects of thyroid surgery, including preoperative assessment, intraoperative techniques, and postoperative care. The survey also explored the use of minimally invasive approaches and the adoption of day surgery or overnight stay procedures. Data were collected through a structured questionnaire. The survey data were analyzed using descriptive statistics and clustering techniques to identify patterns and groupings among surgeons on the basis of their responses.

Results: A variety of practices have emerged among surgeons performing thyroid surgery, with varying preferences for hemostatic methods, additional hemostasis techniques, and the use of drains. A significant proportion of surgeons (47%) still favor traditional inpatient stays for thyroid surgery, whereas others offer day surgery or overnight stays for selected cases (53%). The use of intraoperative nerve monitoring is widespread (73%), but the choice of monitoring methods and the factors influencing its use vary among surgeons. Only 21% of surgeons rely solely on traditional suture ligations for hemostasis, whereas 41% routinely use hemostatic absorbable gauze for additional hemostasis. Minimally invasive approaches, such as Minimally Invasive Video-Assisted Thyroidectomy (MIVAT) (23%) and robotic surgery (7%), are also utilized. Day surgery is offered only in academic hospitals and endocrine surgery referral centers.

Conclusions: Significant variation exists in thyroid surgery practices, emphasizing the need for further research and standardized protocols, particularly in areas such as preoperative assessment, hemostasis techniques, and postoperative care. By establishing best practices, surgeons can confidently expand the offering of day-surgery and one-day surgery options, leading to shorter waiting lists and improved patient care. This shift toward more efficient and patient-centered approaches requires collaborative efforts among surgeons and hospitals to ensure safety and optimal outcomes for patients undergoing thyroid surgery.

目的:2019冠状病毒病(COVID-19)大流行严重影响了选择性甲状腺手术,导致手术次数减少,等待名单增加。作为回应,甲状腺切除术越来越多地作为门诊手术在世界范围内进行,其结果和再入院率与那些在大容量中心手术后过夜的患者相当。然而,在意大利,由于担心这种方法的安全性和有效性,很少进行门诊甲状腺手术。这个特定的时间框架代表了一个独特的机会,可以捕捉意大利甲状腺手术实践的快照,并推动实践变革,同时为大量积压的程序提供实用的解决方案。方法:对意大利外科中心进行调查,评估他们在甲状腺手术各方面的做法和偏好,包括术前评估、术中技术和术后护理。该调查还探讨了微创方法的使用以及采用日间手术或过夜住院程序。数据通过结构化问卷收集。使用描述性统计和聚类技术对调查数据进行分析,以确定外科医生的反应模式和分组。结果:外科医生在进行甲状腺手术时出现了各种各样的做法,对止血方法、附加止血技术和引流管的使用有不同的偏好。相当大比例的外科医生(47%)仍然支持传统的住院甲状腺手术,而其他医生则为特定病例提供日间手术或过夜手术(53%)。术中神经监测的使用很普遍(73%),但监测方法的选择和影响其使用的因素因外科医生而异。只有21%的外科医生完全依靠传统的缝合结扎止血,而41%的外科医生常规使用止血可吸收纱布进行额外止血。微创方法,如微创视频辅助甲状腺切除术(MIVAT)(23%)和机器人手术(7%),也被使用。日间手术只在学术医院和内分泌外科转诊中心提供。结论:甲状腺手术实践存在显著差异,强调需要进一步研究和标准化方案,特别是在术前评估、止血技术和术后护理等领域。通过建立最佳实践,外科医生可以自信地扩大日间手术和日间手术的选择,从而缩短等候名单并改善患者护理。这种向更高效和以患者为中心的方法的转变需要外科医生和医院之间的合作努力,以确保接受甲状腺手术的患者的安全性和最佳结果。
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引用次数: 0
Retrosternal Goitre: What Options? 胸骨后甲状腺肿:有什么选择?
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-12 DOI: 10.62713/aic.3949
Tommaso Loderer, Elena Bonati, Davide Bocchia, Luca Ampollini, Paolo Del Rio

Aim: Goitre is a multifactorial disease whose development is influenced by both genetic and environmental factors. The literature presents no univocal definition of retrosternal goitre. There are more than ten different definitions, making actual classification non-homogeneous. There is no clear consensus concerning the proportion of the gland that must be located in a retrosternal position, nor the depth to which it must descend into the thoracic cavity to be classified as a retrosternal goitre. The therapeutic choice depends on the size of the goitre, the symptomatology, the patient's age, and other patient characteristics. A multidisciplinary evaluation is essential to choosing the best therapeutic approach. Most retrosternal goitres can be safely resected through a cervical approach; however, up to 2% of cases may require a combined cervicothoracic approach. The purpose of this study is to analyze the different surgical approaches used in cases of cervico-mediastinal goitre with real sinking into the thorax, which required a joint surgical procedure with surgeons from the thoracic surgery unit.

Case presentation: From June 2022 to February 2024, 449 patients underwent surgery for thyroid disease at the general surgery unit of the University Hospital of Parma. Of these patients, we analysed the cases of cervico-mediastinal goitre with real sinking into the thorax, which required a joint surgical procedure with colleagues from the thoracic surgery unit due to the goitre's size and location. We identified a series of 5 cases of thoracic goitre, for an incidence rate of 1.1% of the treated patients. In all 5 cases, there was preoperative tracheal compression or dislocation. Of our cases, we found that 2 patients were treated with Kocher cervicotomy, 2 were treated with cervicotomy associated with thoracoscopy (in 1 case, a concomitant mini-thoracotomy at the IV intercostal space was performed), and 1 was treated with cervicotomy associated with manubriotomy. In 2 cases, total thyroidectomy was performed; in 2 cases, two-stage thyroidectomy was performed; and in 1 case, left lobectomy was performed.

Results: Although thoracic goitre is a low-incidence disease, the risks and complications are significantly higher than those of cervical thyroidectomy. Preoperative imaging enables the evaluation of morphology, extension, relationships, and vascularisation, which facilitates preoperative multidisciplinary planning of surgical procedures. Advances in surgical techniques reduce procedure invasiveness by using minimally invasive techniques, which in turn reduce the impact of surgical access, perioperative complications, hospitalisation times, and postoperative recovery.

Conclusions: In our experience, a multidisciplinary approach-in particular, collaboration with thoracic surgeons-is fundamental to improving surgical outcomes.

目的:甲状腺肿是一种多因素疾病,其发展受遗传和环境因素共同影响。文献对胸骨后甲状腺肿没有明确的定义。有十多种不同的定义,使得实际的分类不均匀。关于胸骨后位置的腺的比例,以及它必须下降到胸腔的深度才能被归类为胸骨后甲状腺肿,目前还没有明确的共识。治疗的选择取决于甲状腺肿的大小、症状、患者的年龄和其他患者特征。多学科评估对于选择最佳治疗方法至关重要。大多数胸骨后甲状腺肿可以通过颈椎入路安全切除;然而,高达2%的病例可能需要颈胸联合入路。本研究的目的是分析不同的手术入路在颈部-纵隔甲状腺肿真正沉入胸腔的情况下,这需要胸外科医生的联合手术。病例介绍:从2022年6月到2024年2月,449名患者在帕尔马大学医院的普通外科接受了甲状腺疾病手术。在这些患者中,我们分析了颈部-纵隔甲状腺肿大并真正沉入胸腔的病例,由于甲状腺肿大和位置,需要与胸外科的同事联合手术。我们确定了5例胸部甲状腺肿,发生率为治疗患者的1.1%。5例患者术前均有气管压迫或脱位。在我们的病例中,我们发现2例患者行Kocher颈切开术,2例患者行颈切开术联合胸腔镜(其中1例患者同时行IV肋间隙小开胸术),1例患者行颈切开术联合胸膜切开术。2例行甲状腺全切除术;2例行两期甲状腺切除术;其中1例行左肺叶切除术。结果:胸甲状腺肿虽是一种低发病率的疾病,但其危险性和并发症明显高于宫颈甲状腺切除术。术前成像可以评估形态学、延伸、关系和血管化,从而促进术前多学科手术计划。外科技术的进步通过使用微创技术减少了手术的侵入性,这反过来又减少了手术通道、围手术期并发症、住院时间和术后恢复的影响。结论:根据我们的经验,多学科的方法,特别是与胸外科医生的合作,是提高手术效果的基础。
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引用次数: 0
Clinical Outcomes and Functional Evaluation of Autologous Tendon Grafting for Acromioclavicular Joint Reconstruction. 自体肌腱移植重建肩锁关节的临床效果及功能评价。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-10 DOI: 10.62713/aic.4244
Dongxu Zhao, Yujie Yang, Rui Xie, Sile Hu, Yuhang Lv, Tianjiao Ma, Huricha Zhao, He Zhang, Zejian Jin, Yuntian Yan, Hongxia Sun, Fei Yan

Aim: To evaluate the clinical efficacy and functional outcomes of autologous tendon grafting in reconstructing Rockwood type III-V acromioclavicular (AC) joint dislocations, and to compare its performance with conventional titanium fixation.

Methods: A total of 276 patients who underwent AC joint reconstruction between January 2019 and March 2024 were retrospectively analyzed. Following propensity score matching (PSM), 87 patients were included in the autologous tendon and titanium fixation groups. Primary outcome measures comprised radiographic parameters (acromioclavicular distance [ACD], coracoclavicular distance [CCD], magnetic resonance imaging [MRI] signal intensity), functional scores (Constant-Murley, University of California at Los Angeles [UCLA] shoulder score, visual analog scale [VAS]), biomechanical indices (horizontal motion displacement [HMD], range of motion [ROM] loss ratio, CCD maintenance rate), and complication rates. Prognostic factors were identified using Cox proportional hazards and logistic regression models. An extreme gradient boosting (XGBoost)-based machine learning model was constructed to predict postoperative functional recovery.

Results: After matching, no significant differences in baseline characteristics were observed between groups (n = 87 each). Compared with the titanium group, autologous tendon grafting achieved significantly superior joint stability (ACD, CCD, HMD, ROM loss) and radiological outcomes (tendon signal intensity, bone remodeling score) (all p < 0.01). It was also associated with a lower incidence of redislocation and implant-related failures (p < 0.05). Cox regression identified four independent prognostic factors, including surgical technique, Rockwood classification, preoperative CCD, and ROM limitation. A multivariable risk scoring system demonstrated high predictive accuracy for recurrence at 12 months (area under the curve [AUC] = 0.91). Logistic regression revealed that titanium fixation, Rockwood type V, older age, and impaired bone healing capacity were significant risk factors for complications. The XGBoost model highlighted surgical technique and tissue quality as key predictors of functional recovery, though its external generalizability warrants further validation.

Conclusions: Compared to conventional titanium-based fixation, autologous tendon graft reconstruction yields superior joint stability, improved radiographic outcomes, and better functional scores within 12 months postoperatively, suggesting more favorable early clinical efficacy and biomechanical restoration.

目的:评价自体肌腱移植重建Rockwood III-V型肩锁关节(AC)脱位的临床疗效和功能结局,并与常规钛内固定进行比较。方法:回顾性分析2019年1月至2024年3月期间接受AC关节重建术的276例患者。根据倾向评分匹配(PSM), 87例患者被纳入自体肌腱和钛固定组。主要指标包括影像学参数(肩锁距离[ACD]、喙锁距离[CCD]、磁共振成像[MRI]信号强度)、功能评分(Constant-Murley,加州大学洛杉矶分校[UCLA]肩部评分、视觉模拟量表[VAS])、生物力学指标(水平运动位移[HMD]、运动范围[ROM]损失率、CCD维持率)和并发症发生率。使用Cox比例风险和logistic回归模型确定预后因素。构建了一个基于极限梯度增强(XGBoost)的机器学习模型来预测术后功能恢复。结果:配对后,各组基线特征无显著差异(n = 87)。与钛组相比,自体肌腱移植在关节稳定性(ACD、CCD、HMD、ROM损失)和影像学结果(肌腱信号强度、骨重塑评分)方面均显著优于钛组(均p < 0.01)。它还与较低的再脱位和种植体相关失败发生率相关(p < 0.05)。Cox回归确定了四个独立的预后因素,包括手术技术、Rockwood分类、术前CCD和ROM限制。多变量风险评分系统对12个月复发的预测准确性很高(曲线下面积[AUC] = 0.91)。Logistic回归分析显示,钛固定、Rockwood V型、年龄、骨愈合能力受损是并发症发生的重要危险因素。XGBoost模型强调手术技术和组织质量是功能恢复的关键预测因素,尽管其外部普遍性有待进一步验证。结论:与传统的钛基固定相比,自体肌腱移植重建具有更好的关节稳定性,改善的影像学结果,术后12个月内功能评分更好,提示更有利的早期临床疗效和生物力学恢复。
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引用次数: 0
Comparative Assessment of Individualized Segmentectomy Versus Standard Lobectomy in Patients With Early-Stage Non-Small Cell Lung Cancer. 个体化肺叶切除术与标准肺叶切除术在早期非小细胞肺癌患者中的比较评估。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-10 DOI: 10.62713/aic.4291
Ruishi Wei, Gaoyan Deng, Zhaoxuan Wang, Yongping Liu, Chundong Gu, Jianrong Yu, Jianshui Yang

Aim: The optimal surgical strategy for clinical stage IA non-small cell lung cancer (NSCLC) remains under active investigation. This study aimed to compare the perioperative outcomes, functional preservation, and short-term oncologic results between individualized segmentectomy and standard lobectomy.

Methods: This retrospective cohort study included 205 patients with histologically confirmed clinical stage IA (T1a-cN0M0) NSCLC who underwent surgery at Changzhou Cancer Hospital between January 2017 and June 2023. According to the type of surgical procedure, patients were classified into the individualized segmentectomy group or the standard lobectomy group. Perioperative variables, postoperative complications (graded by Clavien-Dindo classification), pulmonary function recovery (forced expiratory volume in one second (FEV1), diffusing capacity of the lung for carbon monoxide (DLCO)), pain scores (visual analog scale (VAS)), quality of life (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30)), and 2-year recurrence rates were analyzed between these two groups.

Results: A total of 205 NSCLC patients were analyzed in this study (segmentectomy: n = 101; lobectomy: n = 104). Compared with the lobectomy group, the segmentectomy group showed significantly reduced intraoperative blood loss, lower drainage volume, earlier chest tube removal, and a shorter length of hospital stay (p < 0.05). Compared with the lobectomy group, the segmentectomy group had significantly lower early postoperative pain scores and significantly higher quality of life scores (p < 0.05). Pulmonary function was better preserved in the segmentectomy group at both 1 and 3 months postoperatively (p < 0.05). However, no significant difference was observed in the 2-year tumor recurrence rate between the two study groups (p > 0.05).

Conclusions: Individualized segmentectomy offers perioperative and functional advantages over standard lobectomy in patients with early-stage NSCLC, without compromising short-term oncologic safety. These findings support its application as a lung parenchyma-sparing surgical option in appropriately selected patients.

目的:临床IA期非小细胞肺癌(NSCLC)的最佳手术策略仍在积极研究中。本研究旨在比较个体化肺叶切除术和标准肺叶切除术的围手术期预后、功能保存和短期肿瘤学结果。方法:本回顾性队列研究纳入205例组织学证实的临床分期为IA (T1a-cN0M0)的非小细胞肺癌患者,这些患者于2017年1月至2023年6月在常州市肿瘤医院接受手术治疗。根据手术方式将患者分为个体化节段切除术组和标准肺叶切除术组。分析两组患者围手术期变量、术后并发症(Clavien-Dindo分级)、肺功能恢复(1秒用力呼气量(FEV1)、肺一氧化碳弥散量(DLCO))、疼痛评分(视觉模拟量表(VAS))、生活质量(欧洲癌症研究与治疗组织生活质量问卷- core 30 (EORTC QLQ-C30))、2年复发率。结果:本研究共分析了205例NSCLC患者(节段切除术:n = 101;肺叶切除术:n = 104)。与肺叶切除术组相比,节段切除术组术中出血量明显减少,引流量更低,胸管拔除时间更早,住院时间更短(p < 0.05)。与肺叶切除术组相比,节段切除术组术后早期疼痛评分显著降低,生活质量评分显著提高(p < 0.05)。术后1个月和3个月肺功能保存较好(p < 0.05)。两组2年肿瘤复发率差异无统计学意义(p < 0.05)。结论:与标准肺叶切除术相比,个体化肺叶切除术在早期非小细胞肺癌患者的围手术期和功能上具有优势,且不会影响短期肿瘤安全性。这些发现支持其在适当选择的患者中作为肺实质保留手术选择的应用。
{"title":"Comparative Assessment of Individualized Segmentectomy Versus Standard Lobectomy in Patients With Early-Stage Non-Small Cell Lung Cancer.","authors":"Ruishi Wei, Gaoyan Deng, Zhaoxuan Wang, Yongping Liu, Chundong Gu, Jianrong Yu, Jianshui Yang","doi":"10.62713/aic.4291","DOIUrl":"https://doi.org/10.62713/aic.4291","url":null,"abstract":"<p><strong>Aim: </strong>The optimal surgical strategy for clinical stage IA non-small cell lung cancer (NSCLC) remains under active investigation. This study aimed to compare the perioperative outcomes, functional preservation, and short-term oncologic results between individualized segmentectomy and standard lobectomy.</p><p><strong>Methods: </strong>This retrospective cohort study included 205 patients with histologically confirmed clinical stage IA (T1a-cN0M0) NSCLC who underwent surgery at Changzhou Cancer Hospital between January 2017 and June 2023. According to the type of surgical procedure, patients were classified into the individualized segmentectomy group or the standard lobectomy group. Perioperative variables, postoperative complications (graded by Clavien-Dindo classification), pulmonary function recovery (forced expiratory volume in one second (FEV1), diffusing capacity of the lung for carbon monoxide (DLCO)), pain scores (visual analog scale (VAS)), quality of life (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30)), and 2-year recurrence rates were analyzed between these two groups.</p><p><strong>Results: </strong>A total of 205 NSCLC patients were analyzed in this study (segmentectomy: n = 101; lobectomy: n = 104). Compared with the lobectomy group, the segmentectomy group showed significantly reduced intraoperative blood loss, lower drainage volume, earlier chest tube removal, and a shorter length of hospital stay (p < 0.05). Compared with the lobectomy group, the segmentectomy group had significantly lower early postoperative pain scores and significantly higher quality of life scores (p < 0.05). Pulmonary function was better preserved in the segmentectomy group at both 1 and 3 months postoperatively (p < 0.05). However, no significant difference was observed in the 2-year tumor recurrence rate between the two study groups (p > 0.05).</p><p><strong>Conclusions: </strong>Individualized segmentectomy offers perioperative and functional advantages over standard lobectomy in patients with early-stage NSCLC, without compromising short-term oncologic safety. These findings support its application as a lung parenchyma-sparing surgical option in appropriately selected patients.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 11","pages":"1471-1478"},"PeriodicalIF":0.9,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145533853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Clinical Efficacy and Prognostic Impact of Intramedullary Nail Combined With Either Plates or Titanium Cable Internal Fixation in the Treatment of Femoral Subtrochanteric Fractures. 髓内钉联合钢板或钛缆内固定治疗股骨粗隆下骨折的临床疗效及预后影响。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-10 DOI: 10.62713/aic.4304
Liang Zhou, Xue-Qin Zhang, Gang-Xiang Wang
<p><strong>Aim: </strong>This study aims to compare the clinical efficacy of intramedullary nail combined with plate and intramedullary nail combined with titanium cable approaches in the treatment of femoral subtrochanteric fractures.</p><p><strong>Methods: </strong>This retrospective analysis included 85 patients who underwent treatment with intramedullary nails combined with plates and titanium cables at Shengzhou People's Hospital between January 2018 and December 2024. Among them, 40 cases received intramedullary nails combined with plates (the plate group) and 45 cases received intramedullary nails combined with titanium cables (the titanium cable group). Clinical data were collected and compared between the two groups of patients, which included surgery duration, length of hospital stay, incision length, blood loss, fluoroscopy time, fracture healing time, follow-up duration, time to first full weight bearing after surgery, quality of fracture reduction, changes in the neck-shaft angle, complications, and Harris Hip Score.</p><p><strong>Results: </strong>In the titanium cable group, both the incision length and intraoperative blood loss were superior to those in the plate group (p < 0.05). Conversely, the fluoroscopy time and fracture-healing time in the plate group were better than those in the titanium cable group (p < 0.05). Furthermore, both surgical time and length of hospital stay were significantly shorter in the titanium cable group than in the plate group; however, this difference did not achieve statistical significance (p > 0.05). Moreover, there were no significant differences in follow-up duration or time to first full weight-bearing between the two groups (p > 0.05). In the plate group, 2 cases were presented with postoperative complications (5.00%), including 1 case of cerebral infarction and 1 case of deep vein thrombosis. In the titanium cable group, 6 cases had postoperative complications (13.33%), which included 3 cases of delayed varus, 1 case of delayed healing, 1 case of acute coronary syndrome (ACS) combined with delayed varus, and 1 case of nonunion. However, the difference in the overall incidence of postoperative complications between the two groups was not statistically significant (χ<sup>2</sup> = 0.886, p = 0.347). Additionally, no statistically significant differences were observed in the quality of fracture reduction and changes in the neck-shaft angle between the two groups (p > 0.05). Similarly, the Harris Hip Score at the last follow-up between the two groups did not differ significantly (χ<sup>2</sup> = 2.011, p = 0.156).</p><p><strong>Conclusions: </strong>Internal fixation with intramedullary nails combined with titanium cables for unstable femoral subtrochanteric fractures offers advantages of a smaller incision length and less intraoperative blood loss. In contrast, internal fixation with intramedullary nails combined with locking plates requires less fluoroscopy time, faster fracture healing, and few
目的:比较髓内钉联合钢板入路与髓内钉联合钛缆入路治疗股骨粗隆下骨折的临床疗效。方法:回顾性分析2018年1月至2024年12月在嵊州市人民医院行髓内钉联合钢板钛缆治疗的85例患者。其中髓内钉联合钢板组(钢板组)40例,髓内钉联合钛缆组(钛缆组)45例。收集两组患者的临床资料进行比较,包括手术时间、住院时间、切口长度、出血量、透视时间、骨折愈合时间、随访时间、术后首次完全负重时间、骨折复位质量、颈轴角度变化、并发症、Harris髋关节评分。结果:钛缆组切口长度和术中出血量均优于钢板组(p < 0.05)。相反,钢板组透视时间和骨折愈合时间优于钛缆组(p < 0.05)。钛缆组手术时间和住院时间均明显短于钢板组;但差异无统计学意义(p < 0.05)。两组患者随访时间及首次完全负重时间差异无统计学意义(p < 0.05)。钢板组出现术后并发症2例(5.00%),其中脑梗死1例,深静脉血栓形成1例。钛缆组术后并发症6例(13.33%),其中迟发性内翻3例,迟发性愈合1例,急性冠脉综合征(ACS)合并迟发性内翻1例,骨不连1例。两组患者术后并发症总发生率比较,差异无统计学意义(χ2 = 0.886, p = 0.347)。两组骨折复位质量及颈轴角变化差异无统计学意义(p < 0.05)。同样,两组在最后一次随访时Harris髋关节评分也无显著差异(χ2 = 2.011, p = 0.156)。结论:髓内钉联合钛缆内固定治疗不稳定股粗隆下骨折切口长度小,术中出血量少。相比之下,髓内钉联合锁定钢板内固定所需的透视时间更短,骨折愈合更快,并发症更少。这两种方法都有各自的优势和局限性,为手术决策提供了有希望的指导,并取得了良好的结果。
{"title":"The Clinical Efficacy and Prognostic Impact of Intramedullary Nail Combined With Either Plates or Titanium Cable Internal Fixation in the Treatment of Femoral Subtrochanteric Fractures.","authors":"Liang Zhou, Xue-Qin Zhang, Gang-Xiang Wang","doi":"10.62713/aic.4304","DOIUrl":"https://doi.org/10.62713/aic.4304","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;This study aims to compare the clinical efficacy of intramedullary nail combined with plate and intramedullary nail combined with titanium cable approaches in the treatment of femoral subtrochanteric fractures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This retrospective analysis included 85 patients who underwent treatment with intramedullary nails combined with plates and titanium cables at Shengzhou People's Hospital between January 2018 and December 2024. Among them, 40 cases received intramedullary nails combined with plates (the plate group) and 45 cases received intramedullary nails combined with titanium cables (the titanium cable group). Clinical data were collected and compared between the two groups of patients, which included surgery duration, length of hospital stay, incision length, blood loss, fluoroscopy time, fracture healing time, follow-up duration, time to first full weight bearing after surgery, quality of fracture reduction, changes in the neck-shaft angle, complications, and Harris Hip Score.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In the titanium cable group, both the incision length and intraoperative blood loss were superior to those in the plate group (p &lt; 0.05). Conversely, the fluoroscopy time and fracture-healing time in the plate group were better than those in the titanium cable group (p &lt; 0.05). Furthermore, both surgical time and length of hospital stay were significantly shorter in the titanium cable group than in the plate group; however, this difference did not achieve statistical significance (p &gt; 0.05). Moreover, there were no significant differences in follow-up duration or time to first full weight-bearing between the two groups (p &gt; 0.05). In the plate group, 2 cases were presented with postoperative complications (5.00%), including 1 case of cerebral infarction and 1 case of deep vein thrombosis. In the titanium cable group, 6 cases had postoperative complications (13.33%), which included 3 cases of delayed varus, 1 case of delayed healing, 1 case of acute coronary syndrome (ACS) combined with delayed varus, and 1 case of nonunion. However, the difference in the overall incidence of postoperative complications between the two groups was not statistically significant (χ&lt;sup&gt;2&lt;/sup&gt; = 0.886, p = 0.347). Additionally, no statistically significant differences were observed in the quality of fracture reduction and changes in the neck-shaft angle between the two groups (p &gt; 0.05). Similarly, the Harris Hip Score at the last follow-up between the two groups did not differ significantly (χ&lt;sup&gt;2&lt;/sup&gt; = 2.011, p = 0.156).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Internal fixation with intramedullary nails combined with titanium cables for unstable femoral subtrochanteric fractures offers advantages of a smaller incision length and less intraoperative blood loss. In contrast, internal fixation with intramedullary nails combined with locking plates requires less fluoroscopy time, faster fracture healing, and few","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 11","pages":"1521-1529"},"PeriodicalIF":0.9,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of a Responsibility System Management Model on Deep Vein Thrombosis and Functional Recovery Following Internal Fixation for Pelvic Fractures. 责任制管理模式对骨盆骨折内固定术后深静脉血栓形成及功能恢复的影响。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-10 DOI: 10.62713/aic.4364
Meilan Ding, Li Huang

Aim: This study evaluates the impact of a responsibility system management model in patients undergoing internal fixation for pelvic fractures, by examining the incidence of deep vein thrombosis (DVT) and postoperative pelvic functional recovery.

Methods: This retrospective observational study included 145 patients who underwent internal fixation for pelvic fractures at Ganzhou People's Hospital between January 2022 and October 2024. Based on the nursing model, patients were categorized into a responsibility care group (n = 70), which received responsibility system management nursing care and a conventional care group (n = 75), which was managed through conventional postoperative care. The incidence of postoperative lower extremity DVT was compared between the two groups. Furthermore, pelvic function was assessed using the Majeed Pelvic Score and pain levels were evaluated using the Visual Analogue Scale (VAS). Additional parameters assessed were postoperative recovery, compliance with mechanical prophylaxis, and nursing satisfaction.

Results: The responsibility system management care group demonstrated a significantly lower incidence of postoperative lower extremity DVT compared to the conventional care group (p < 0.05). Furthermore, the responsibility care group had significantly higher postoperative Majeed functional scores, lower VAS pain scores (p < 0.05), better overall recovery, longer duration of mechanical prophylaxis use, and higher nursing satisfaction (p < 0.05).

Conclusions: The responsibility system management nursing model was significantly associated with a lower risk of early DVT and better short-term pelvic functional recovery during hospitalization. This model represents a promising postoperative management strategy; however, its long-term efficacy and generalizability require further validation through multicenter prospective studies with extended follow-up.

目的:本研究通过观察深静脉血栓形成(DVT)发生率和术后盆腔功能恢复情况,评价责任制管理模式对骨盆骨折内固定患者的影响。方法:本回顾性观察研究纳入2022年1月至2024年10月在赣州市人民医院行骨盆骨折内固定治疗的145例患者。根据护理模式,将患者分为责任护理组(n = 70)和常规护理组(n = 75),分别接受责任制管理护理和术后常规护理管理。比较两组患者术后下肢深静脉血栓的发生率。此外,使用Majeed骨盆评分评估骨盆功能,使用视觉模拟量表(VAS)评估疼痛水平。评估的其他参数包括术后恢复、机械预防依从性和护理满意度。结果:责任制管理护理组术后下肢DVT发生率明显低于常规护理组(p < 0.05)。此外,责任护理组术后Majeed功能评分较高,VAS疼痛评分较低(p < 0.05),整体恢复较好,机械预防使用时间较长,护理满意度较高(p < 0.05)。结论:责任制管理护理模式与住院期间早期DVT发生风险较低、短期盆腔功能恢复较好相关。这种模式代表了一种很有前途的术后管理策略;然而,其长期疗效和可推广性需要通过多中心前瞻性研究和长期随访进一步验证。
{"title":"Impact of a Responsibility System Management Model on Deep Vein Thrombosis and Functional Recovery Following Internal Fixation for Pelvic Fractures.","authors":"Meilan Ding, Li Huang","doi":"10.62713/aic.4364","DOIUrl":"10.62713/aic.4364","url":null,"abstract":"<p><strong>Aim: </strong>This study evaluates the impact of a responsibility system management model in patients undergoing internal fixation for pelvic fractures, by examining the incidence of deep vein thrombosis (DVT) and postoperative pelvic functional recovery.</p><p><strong>Methods: </strong>This retrospective observational study included 145 patients who underwent internal fixation for pelvic fractures at Ganzhou People's Hospital between January 2022 and October 2024. Based on the nursing model, patients were categorized into a responsibility care group (n = 70), which received responsibility system management nursing care and a conventional care group (n = 75), which was managed through conventional postoperative care. The incidence of postoperative lower extremity DVT was compared between the two groups. Furthermore, pelvic function was assessed using the Majeed Pelvic Score and pain levels were evaluated using the Visual Analogue Scale (VAS). Additional parameters assessed were postoperative recovery, compliance with mechanical prophylaxis, and nursing satisfaction.</p><p><strong>Results: </strong>The responsibility system management care group demonstrated a significantly lower incidence of postoperative lower extremity DVT compared to the conventional care group (p < 0.05). Furthermore, the responsibility care group had significantly higher postoperative Majeed functional scores, lower VAS pain scores (p < 0.05), better overall recovery, longer duration of mechanical prophylaxis use, and higher nursing satisfaction (p < 0.05).</p><p><strong>Conclusions: </strong>The responsibility system management nursing model was significantly associated with a lower risk of early DVT and better short-term pelvic functional recovery during hospitalization. This model represents a promising postoperative management strategy; however, its long-term efficacy and generalizability require further validation through multicenter prospective studies with extended follow-up.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 11","pages":"1479-1486"},"PeriodicalIF":0.9,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Neoadjuvant Chemotherapy Combined With Modified Radical Mastectomy on Immune Function, Oxidative Stress, and Prognosis in Patients With Different Molecular Subtypes of Breast Cancer. 新辅助化疗联合改良根治术对不同分子亚型乳腺癌患者免疫功能、氧化应激及预后的影响
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-10 DOI: 10.62713/aic.4263
Danxia Cao, Yi Sun, Hongying Pan
<p><strong>Aim: </strong>The objective of this study is to explore the impact of neoadjuvant chemotherapy (NACT) combined with modified radical mastectomy on immune function, oxidative stress and prognosis in patients with different molecular subtypes of breast cancer (BC).</p><p><strong>Methods: </strong>A total of 150 patients diagnosed with BC who received NACT and modified radical mastectomy from January 2020 to January 2024 were collected for retrospective analysis. All patients were divided into four groups according to the molecular subtype: luminal A group (n = 39), luminal B group (n = 44), human epidermal growth factor receptor 2 (HER-2) overexpression group (n = 34), and triple-negative group (n = 33). Data on pathological complete remission (pCR), recurrence, recurrence-free survival (RFS) and overall survival (OS) were collected. The serum levels of malondialdehyde (MDA), superoxide dismutase (SOD), interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF-α) were detected using assay kits.</p><p><strong>Results: </strong>The pCR rate of the entire sample cohort was 20.67% after NACT, with a recurrence rate during follow-up recorded at 22.67%. The pCR rate was significantly higher in the HER-2 overexpression group (13/34, 38.24%) than in the triple-negative (11/33, 33.33%), luminal A (1/39, 2.56%), and luminal B groups (6/44, 13.64%) (p < 0.001). Compared to the triple-negative (10/33, 30.30%), luminal A (5/39, 12.82%), and luminal B groups (6/44, 13.64%), the HER-2 overexpression group (13/34, 38.24%) had a significantly higher recurrence rate (p = 0.019). Both HER-2 overexpression and triple-negative groups also featured greater changes in IL-6, TNF-α, and SOD levels than the luminal A and luminal B groups (p < 0.05). Changes in MDA levels were the greatest in the HER-2 overexpression group among the tested group (p < 0.05). HER-2 overexpression was identified as the independent risk factor affecting RFS (hazard ratio [HR] = 3.883; 95% confidence interval [CI] = 1.371-11.004; p = 0.011). Clinical stage III (HR = 2.031; 95% CI = 1.023-4.030; p = 0.043), pCR (HR = 0.111; 95% CI = 0.015-0.809; p = 0.030) and recurrence (HR = 4.512; 95% CI = 2.412-8.441; p < 0.001) were the independent factors affecting OS in BC patients. The Kaplan-Meier curve analysis demonstrated significant differences in RFS among the four patient groups (p = 0.005), with no marked differences in OS (p = 0.303). The RFS of the HER-2 overexpression group was shorter than that of the other groups.</p><p><strong>Conclusions: </strong>In BC patients undergoing NACT combined with modified radical mastectomy, the HER-2 overexpression subtype was associated with a shorter RFS. However, no significant differences in OS were observed among the four molecular subtypes during the follow-up period. Inflammatory and oxidative stress markers showed improvements three months postoperatively across all subtypes, with more pronounced changes observed in the
目的:探讨新辅助化疗(NACT)联合改良根治术对不同分子亚型乳腺癌(BC)患者免疫功能、氧化应激及预后的影响。方法:收集2020年1月至2024年1月诊断为BC并接受NACT和改良乳房根治术的150例患者进行回顾性分析。所有患者根据分子亚型分为4组:luminal A组(n = 39)、luminal B组(n = 44)、human epidermal growth factor receptor 2 (HER-2)过表达组(n = 34)、三阴性组(n = 33)。收集病理完全缓解(pCR)、复发、无复发生存期(RFS)和总生存期(OS)的数据。采用试剂盒检测血清丙二醛(MDA)、超氧化物歧化酶(SOD)、白细胞介素-6 (IL-6)、白细胞介素-8 (IL-8)、肿瘤坏死因子α (TNF-α)水平。结果:NACT后整个样本队列的pCR率为20.67%,随访复发率为22.67%。HER-2过表达组的pCR率(13/34,38.24%)显著高于三阴性组(11/33,33.33%)、luminal A组(1/39,2.56%)和luminal B组(6/44,13.64%)(p < 0.001)。HER-2过表达组(13/34,38.24%)的复发率明显高于三阴性组(10/33,30.30%)、管腔A组(5/39,12.82%)和管腔B组(6/44,13.64%)(p = 0.019)。HER-2过表达组和三阴性组IL-6、TNF-α、SOD水平的变化均高于腔内A、B组(p < 0.05)。MDA水平变化以HER-2过表达组最大(p < 0.05)。HER-2过表达是影响RFS的独立危险因素(风险比[HR] = 3.883; 95%可信区间[CI] = 1.371-11.004; p = 0.011)。临床III期(HR = 2.031, 95% CI = 1.023-4.030, p = 0.043)、pCR (HR = 0.111, 95% CI = 0.015-0.809, p = 0.030)和复发(HR = 4.512, 95% CI = 2.412-8.441, p < 0.001)是影响BC患者OS的独立因素。Kaplan-Meier曲线分析显示,4组患者RFS差异有统计学意义(p = 0.005), OS差异无统计学意义(p = 0.303)。HER-2过表达组的RFS较其他组短。结论:在接受NACT联合改良根治性乳房切除术的BC患者中,HER-2过表达亚型与较短的RFS相关。然而,在随访期间,四种分子亚型之间的OS无显著差异。术后3个月,所有亚型的炎症和氧化应激标志物均有所改善,HER-2过表达和三阴性亚型的变化更为明显。
{"title":"Impact of Neoadjuvant Chemotherapy Combined With Modified Radical Mastectomy on Immune Function, Oxidative Stress, and Prognosis in Patients With Different Molecular Subtypes of Breast Cancer.","authors":"Danxia Cao, Yi Sun, Hongying Pan","doi":"10.62713/aic.4263","DOIUrl":"https://doi.org/10.62713/aic.4263","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;The objective of this study is to explore the impact of neoadjuvant chemotherapy (NACT) combined with modified radical mastectomy on immune function, oxidative stress and prognosis in patients with different molecular subtypes of breast cancer (BC).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 150 patients diagnosed with BC who received NACT and modified radical mastectomy from January 2020 to January 2024 were collected for retrospective analysis. All patients were divided into four groups according to the molecular subtype: luminal A group (n = 39), luminal B group (n = 44), human epidermal growth factor receptor 2 (HER-2) overexpression group (n = 34), and triple-negative group (n = 33). Data on pathological complete remission (pCR), recurrence, recurrence-free survival (RFS) and overall survival (OS) were collected. The serum levels of malondialdehyde (MDA), superoxide dismutase (SOD), interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF-α) were detected using assay kits.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The pCR rate of the entire sample cohort was 20.67% after NACT, with a recurrence rate during follow-up recorded at 22.67%. The pCR rate was significantly higher in the HER-2 overexpression group (13/34, 38.24%) than in the triple-negative (11/33, 33.33%), luminal A (1/39, 2.56%), and luminal B groups (6/44, 13.64%) (p &lt; 0.001). Compared to the triple-negative (10/33, 30.30%), luminal A (5/39, 12.82%), and luminal B groups (6/44, 13.64%), the HER-2 overexpression group (13/34, 38.24%) had a significantly higher recurrence rate (p = 0.019). Both HER-2 overexpression and triple-negative groups also featured greater changes in IL-6, TNF-α, and SOD levels than the luminal A and luminal B groups (p &lt; 0.05). Changes in MDA levels were the greatest in the HER-2 overexpression group among the tested group (p &lt; 0.05). HER-2 overexpression was identified as the independent risk factor affecting RFS (hazard ratio [HR] = 3.883; 95% confidence interval [CI] = 1.371-11.004; p = 0.011). Clinical stage III (HR = 2.031; 95% CI = 1.023-4.030; p = 0.043), pCR (HR = 0.111; 95% CI = 0.015-0.809; p = 0.030) and recurrence (HR = 4.512; 95% CI = 2.412-8.441; p &lt; 0.001) were the independent factors affecting OS in BC patients. The Kaplan-Meier curve analysis demonstrated significant differences in RFS among the four patient groups (p = 0.005), with no marked differences in OS (p = 0.303). The RFS of the HER-2 overexpression group was shorter than that of the other groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;In BC patients undergoing NACT combined with modified radical mastectomy, the HER-2 overexpression subtype was associated with a shorter RFS. However, no significant differences in OS were observed among the four molecular subtypes during the follow-up period. Inflammatory and oxidative stress markers showed improvements three months postoperatively across all subtypes, with more pronounced changes observed in the ","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 11","pages":"1530-1540"},"PeriodicalIF":0.9,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Preoperative Systemic Inflammation Response Index and Postoperative Recurrence in Patients With Intrahepatic Bile Duct Stones. 肝内胆管结石患者术前全身炎症反应指数与术后复发的关系
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-10 DOI: 10.62713/aic.4288
Musu Pan, Xiaolin Ye, Lei Zhou, Linxun Liu

Aim: Intrahepatic bile duct stones (IHBDS) are characterized by a high postoperative recurrence rate. Their pathophysiological core lies in a vicious cycle of bile stasis, infection, and inflammation. Inflammatory responses play a crucial role in the onset, progression, and recurrence of IHBDS. This study aimed to evaluate the predictive performance of the preoperative systemic inflammation response index (SIRI) for postoperative recurrence in patients with IHBDS.

Methods: This retrospective study analyzed 152 patients with IHBDS who underwent surgical resection between January 2018 and December 2024. Data, including demographic characteristics, comorbidities, and preoperative laboratory parameters, were collected. Receiver operating characteristic (ROC) curve analysis was used to determine the optimal cut-off values for the systemic immune-inflammation index (SII), SIRI, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR). Furthermore, multivariate logistic regression analysis was performed to identify independent risk factors for postoperative recurrence.

Results: ROC analysis demonstrated that SIRI had superior predictive performance compared with SII, NLR, MLR, and PLR, with an area under the curve (AUC) of 0.756 (95% confidence interval [CI]: 0.671-0.842). Multivariate analysis identified prior IHBDS-related surgical history (odds ratio [OR] = 3.06, 95% CI: 1.28-7.34, p = 0.012), preoperative SIRI (OR = 1.81, 95% CI: 1.21-2.72, p = 0.004), and total bilirubin level (OR = 1.07, 95% CI: 1.02-1.13, p = 0.011) as independent risk factors for postoperative recurrence.

Conclusions: Preoperative SIRI is a novel, independent, and readily detectable biomarker for predicting postoperative recurrence in patients with IHBDS. When combined with a history of prior biliary surgery and total bilirubin levels, SIRI can aid in risk stratification and guide surgical planning and postoperative management.

目的:肝内胆管结石(IHBDS)具有术后复发率高的特点。其病理生理核心在于胆汁淤积、感染和炎症的恶性循环。炎症反应在IHBDS的发病、进展和复发中起着至关重要的作用。本研究旨在评估术前全身炎症反应指数(SIRI)对IHBDS患者术后复发的预测性能。方法:本回顾性研究分析了2018年1月至2024年12月期间接受手术切除的152例IHBDS患者。收集数据,包括人口统计学特征、合并症和术前实验室参数。采用受试者工作特征(ROC)曲线分析确定全身免疫炎症指数(SII)、SIRI、中性粒细胞与淋巴细胞比值(NLR)、单核细胞与淋巴细胞比值(MLR)和血小板与淋巴细胞比值(PLR)的最佳临界值。此外,进行多因素logistic回归分析以确定术后复发的独立危险因素。结果:ROC分析显示,SIRI的预测性能优于SII、NLR、MLR和PLR,曲线下面积(AUC)为0.756(95%可信区间[CI]: 0.671-0.842)。多因素分析发现既往ihbds相关手术史(比值比[OR] = 3.06, 95% CI: 1.28-7.34, p = 0.012)、术前SIRI (OR = 1.81, 95% CI: 1.21-2.72, p = 0.004)和总胆红素水平(OR = 1.07, 95% CI: 1.02-1.13, p = 0.011)是术后复发的独立危险因素。结论:术前SIRI是预测IHBDS患者术后复发的一种新颖、独立且易于检测的生物标志物。当与胆道手术史和总胆红素水平相结合时,SIRI可以帮助风险分层,指导手术计划和术后管理。
{"title":"Association Between Preoperative Systemic Inflammation Response Index and Postoperative Recurrence in Patients With Intrahepatic Bile Duct Stones.","authors":"Musu Pan, Xiaolin Ye, Lei Zhou, Linxun Liu","doi":"10.62713/aic.4288","DOIUrl":"https://doi.org/10.62713/aic.4288","url":null,"abstract":"<p><strong>Aim: </strong>Intrahepatic bile duct stones (IHBDS) are characterized by a high postoperative recurrence rate. Their pathophysiological core lies in a vicious cycle of bile stasis, infection, and inflammation. Inflammatory responses play a crucial role in the onset, progression, and recurrence of IHBDS. This study aimed to evaluate the predictive performance of the preoperative systemic inflammation response index (SIRI) for postoperative recurrence in patients with IHBDS.</p><p><strong>Methods: </strong>This retrospective study analyzed 152 patients with IHBDS who underwent surgical resection between January 2018 and December 2024. Data, including demographic characteristics, comorbidities, and preoperative laboratory parameters, were collected. Receiver operating characteristic (ROC) curve analysis was used to determine the optimal cut-off values for the systemic immune-inflammation index (SII), SIRI, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR). Furthermore, multivariate logistic regression analysis was performed to identify independent risk factors for postoperative recurrence.</p><p><strong>Results: </strong>ROC analysis demonstrated that SIRI had superior predictive performance compared with SII, NLR, MLR, and PLR, with an area under the curve (AUC) of 0.756 (95% confidence interval [CI]: 0.671-0.842). Multivariate analysis identified prior IHBDS-related surgical history (odds ratio [OR] = 3.06, 95% CI: 1.28-7.34, p = 0.012), preoperative SIRI (OR = 1.81, 95% CI: 1.21-2.72, p = 0.004), and total bilirubin level (OR = 1.07, 95% CI: 1.02-1.13, p = 0.011) as independent risk factors for postoperative recurrence.</p><p><strong>Conclusions: </strong>Preoperative SIRI is a novel, independent, and readily detectable biomarker for predicting postoperative recurrence in patients with IHBDS. When combined with a history of prior biliary surgery and total bilirubin levels, SIRI can aid in risk stratification and guide surgical planning and postoperative management.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 11","pages":"1552-1559"},"PeriodicalIF":0.9,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound-Guided vs. Conventional Dorsoulnar Fragment Reduction Combined With Volar Locking Plate Fixation for Distal Radius Fractures: A Comparative Clinical Study. 超声引导下与传统背椎体碎片复位联合掌侧锁定钢板固定桡骨远端骨折的临床比较研究。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-10 DOI: 10.62713/aic.4258
Zuobing Shi, Daming Lu, Mingxing Zhao, Yunfang Fan, Shouzheng Liu, Jun Su

Aim: Distal radius fractures (DRFs) are among the most common traumatic injuries. Reduction of dorsoulnar fragments combined with volar locking plate fixation yields satisfactory outcomes. However, conventional fluoroscopy-guided techniques present inherent limitations in accuracy. This study aimed to evaluate the feasibility and efficacy of ultrasound-guided reduction of dorsoulnar fragment (DUF) combined with volar locking plate fixation for DRFs.

Methods: This retrospective study included 116 patients with DRFs who underwent reduction of dorsoulnar fragments combined with volar locking plate fixation at our hospital between January 2022 and January 2024. Patients were allocated into two groups based on the intraoperative guidance technique: the observation group (n = 54, ultrasound-guided) and the control group (n = 62, X-ray-guided). Surgical indicators, healing progress, and outcome measures were assessed, including wrist function (Gartland-Werley score), range of motion (dorsiflexion, volar flexion, supination, pronation), radiological parameters (volar tilt, radial inclination, radial height), Visual Analog Scale (VAS) score, Modified Mayo Wrist Score (MMWS), grip strength, and complications.

Results: Baseline characteristics and all preoperative outcome metrics (Gartland-Werley score, range of motion, radiological parameters, VAS score, MMWS, grip strength) showed no significant differences between the two groups (p > 0.05). The observation group demonstrated significantly shorter operation time, less intraoperative blood loss, and reduced hospital stay compared to the control group (p < 0.05). No significant difference in fracture healing time was observed (p > 0.05). Postoperatively, both groups exhibited significant reductions in Gartland-Werley scores (p < 0.001), with lower scores in the observation group (p < 0.001). Dorsiflexion, volar flexion, pronation, and supination angles significantly improved in both groups (p < 0.001); the observation group demonstrated larger dorsiflexion, pronation and supination angles (p < 0.001), but no intergroup difference was observed in volar flexion (p > 0.05). The radiological outcomes improved significantly in both groups postoperatively (p < 0.001). The observation group achieved superior volar tilt and radial height (p < 0.001), while radial inclination showed no significant difference (p > 0.05). The complication rate was significantly lower in the observation group than in the control group (p < 0.05).

Conclusions: Ultrasound-guided reduction of dorsoulnar fragments combined with volar locking plate fixation significantly enhanced postoperative wrist function, anatomical alignment, and reduced complication rates compared to conventional X-ray guidance. These findings suggest that intraoperative ultrasound is a valuable adjunct for dorsoulnar fragment (DUF) reduction in DRF fixation, contributing to great

目的:桡骨远端骨折是最常见的外伤性损伤之一。背椎体碎片复位联合掌侧锁定钢板固定效果满意。然而,传统的透视引导技术在准确性上存在固有的局限性。本研究旨在评价超声引导下背椎体碎片复位联合掌侧锁定钢板固定DRFs的可行性和疗效。方法:本回顾性研究纳入了2022年1月至2024年1月在我院接受背椎体碎片复位联合掌侧锁定钢板固定的116例DRFs患者。根据术中引导方式将患者分为两组:观察组(54例,超声引导)和对照组(62例,x线引导)。评估手术指标、愈合进展和结局指标,包括手腕功能(Gartland-Werley评分)、活动范围(背屈、掌屈、旋后、旋前)、放射学参数(掌侧倾斜、径向倾斜、径向高度)、视觉模拟量表(VAS)评分、改良梅奥手腕评分(MMWS)、握力和并发症。结果:基线特征和所有术前预后指标(Gartland-Werley评分、活动范围、放射学参数、VAS评分、MMWS、握力)在两组间无显著差异(p < 0.05)。观察组患者手术时间明显缩短,术中出血量明显减少,住院时间明显缩短(p < 0.05)。两组骨折愈合时间差异无统计学意义(p < 0.05)。两组术后Gartland-Werley评分均显著降低(p < 0.001),观察组评分较低(p < 0.001)。两组患者背屈、掌屈、旋前、旋后角度均显著改善(p < 0.001);观察组背屈、旋前、旋后角度较大(p < 0.001),掌侧屈曲组间差异无统计学意义(p < 0.05)。两组术后放射学指标均有显著改善(p < 0.001)。观察组掌侧倾角和桡骨高度均优于对照组(p < 0.001),而桡骨倾角差异无统计学意义(p < 0.05)。观察组并发症发生率明显低于对照组(p < 0.05)。结论:与传统的x线引导相比,超声引导下的背跖骨碎片复位联合掌侧锁定钢板固定可显著增强术后腕关节功能,改善解剖结构,降低并发症发生率。这些发现表明术中超声是DRF固定中减少背椎体碎片(DUF)的一种有价值的辅助手段,有助于提高精度和改善临床结果。
{"title":"Ultrasound-Guided vs. Conventional Dorsoulnar Fragment Reduction Combined With Volar Locking Plate Fixation for Distal Radius Fractures: A Comparative Clinical Study.","authors":"Zuobing Shi, Daming Lu, Mingxing Zhao, Yunfang Fan, Shouzheng Liu, Jun Su","doi":"10.62713/aic.4258","DOIUrl":"https://doi.org/10.62713/aic.4258","url":null,"abstract":"<p><strong>Aim: </strong>Distal radius fractures (DRFs) are among the most common traumatic injuries. Reduction of dorsoulnar fragments combined with volar locking plate fixation yields satisfactory outcomes. However, conventional fluoroscopy-guided techniques present inherent limitations in accuracy. This study aimed to evaluate the feasibility and efficacy of ultrasound-guided reduction of dorsoulnar fragment (DUF) combined with volar locking plate fixation for DRFs.</p><p><strong>Methods: </strong>This retrospective study included 116 patients with DRFs who underwent reduction of dorsoulnar fragments combined with volar locking plate fixation at our hospital between January 2022 and January 2024. Patients were allocated into two groups based on the intraoperative guidance technique: the observation group (n = 54, ultrasound-guided) and the control group (n = 62, X-ray-guided). Surgical indicators, healing progress, and outcome measures were assessed, including wrist function (Gartland-Werley score), range of motion (dorsiflexion, volar flexion, supination, pronation), radiological parameters (volar tilt, radial inclination, radial height), Visual Analog Scale (VAS) score, Modified Mayo Wrist Score (MMWS), grip strength, and complications.</p><p><strong>Results: </strong>Baseline characteristics and all preoperative outcome metrics (Gartland-Werley score, range of motion, radiological parameters, VAS score, MMWS, grip strength) showed no significant differences between the two groups (p > 0.05). The observation group demonstrated significantly shorter operation time, less intraoperative blood loss, and reduced hospital stay compared to the control group (p < 0.05). No significant difference in fracture healing time was observed (p > 0.05). Postoperatively, both groups exhibited significant reductions in Gartland-Werley scores (p < 0.001), with lower scores in the observation group (p < 0.001). Dorsiflexion, volar flexion, pronation, and supination angles significantly improved in both groups (p < 0.001); the observation group demonstrated larger dorsiflexion, pronation and supination angles (p < 0.001), but no intergroup difference was observed in volar flexion (p > 0.05). The radiological outcomes improved significantly in both groups postoperatively (p < 0.001). The observation group achieved superior volar tilt and radial height (p < 0.001), while radial inclination showed no significant difference (p > 0.05). The complication rate was significantly lower in the observation group than in the control group (p < 0.05).</p><p><strong>Conclusions: </strong>Ultrasound-guided reduction of dorsoulnar fragments combined with volar locking plate fixation significantly enhanced postoperative wrist function, anatomical alignment, and reduced complication rates compared to conventional X-ray guidance. These findings suggest that intraoperative ultrasound is a valuable adjunct for dorsoulnar fragment (DUF) reduction in DRF fixation, contributing to great","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 11","pages":"1560-1570"},"PeriodicalIF":0.9,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145534174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic Evaluation of Femoral Offset Reconstruction in Hip Arthroplasty: A Retrospective Analysis. 髋关节置换术中股骨偏移重建的影像学评价:回顾性分析。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-11-10 DOI: 10.62713/aic.4334
Weixuan Zheng, Chengsheng Wu, Hongmei Xu

Aim: To investigate the impact of femoral offset (FO) reconstruction on postoperative hip function recovery and complication rates following total hip arthroplasty (THA) via the posterolateral approach.

Methods: A retrospective analysis was performed on 146 patients who underwent primary unilateral THA between January 2019 and April 2024. Patients were divided into two groups based on whether the postoperative FO difference (≤4 mm vs. >4 mm): the reconstruction group (n = 92) and the control group (n = 54). Baseline characteristics, radiographic parameters, postoperative functional outcomes (Harris Hip Score (HHS), visual analogue scale (VAS) for pain, and gait parameters), complications, and prosthesis failure cases were compared between the groups, accompanied by a representative case analysis.

Results: No significant differences were observed in baseline data between the two groups (p > 0.05). Compared with the control group, the postoperative FO in the reconstruction group was significantly closer to that of the contralateral healthy side (p < 0.05). There were no significant differences in acetabular prosthesis parameters between the two groups (p > 0.05). However, the femoral stem neck-shaft angle in the control group was significantly smaller than in the reconstruction group (p < 0.05). At all postoperative time points, the reconstruction group demonstrated superior outcomes in HHS, VAS, and gait parameters than the control group (p < 0.05). The incidence of complications was significantly lower in the reconstruction group than that in the control group (p < 0.05), whereas no significant difference was found in prosthesis revision rates (p > 0.05). Representative cases indicated that patients who failed to achieve FO reconstruction criteria were more susceptible to postoperative dislocation.

Conclusions: Precise femoral offset reconstruction contributes to improved postoperative hip function and a reduced risk of complications in THA.

目的:探讨经后外侧入路全髋关节置换术(THA)后股骨偏置(FO)重建对术后髋关节功能恢复及并发症发生率的影响。方法:对2019年1月至2024年4月期间接受原发性单侧THA手术的146例患者进行回顾性分析。根据术后FO差异(≤4mm vs. > 4mm)将患者分为重建组(n = 92)和对照组(n = 54)两组。比较两组患者的基线特征、影像学参数、术后功能结局(Harris髋关节评分(HHS)、疼痛视觉模拟评分(VAS)和步态参数)、并发症和假体失效病例,并进行代表性病例分析。结果:两组患者基线资料差异无统计学意义(p < 0.05)。与对照组相比,重建组术后FO明显接近对侧健康侧(p < 0.05)。两组患者髋臼假体参数比较差异无统计学意义(p < 0.05)。对照组股骨干颈轴角明显小于重建组(p < 0.05)。在术后所有时间点,重建组在HHS、VAS和步态参数方面均优于对照组(p < 0.05)。重建组并发症发生率明显低于对照组(p < 0.05),假体翻修率差异无统计学意义(p < 0.05)。有代表性的病例表明,未达到FO重建标准的患者更容易发生术后脱位。结论:精确的股骨偏置重建有助于改善THA术后髋关节功能并降低并发症的风险。
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Annali italiani di chirurgia
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