Pub Date : 2022-04-11DOI: 10.33696/gastroenterology.3.038
Vishnu P. Tripathi, Daniel Goo, Bokyo N Maidya, M. K. Aneebuddin
Vishnu P. Tripathi1, Daniel Goo2, Bokyo N Maidya3, M K Aneebuddin4 1Department of Biotechnology, V.B.S. Purvanchal University, Jaunpur, India 2Department of Biomedical Engineering, University of Memphis, USA 3Department of Gastroenterology, Uzhhorod National University, Ukraine 4Department of Pharmaceutics, Shadan College of Pharmacy, Telangana State, India *Correspondence should be addressed to Vishnu P. Tripathi, tripatipvishnu@gmail.com
Vishnu P. Tripathi1, Daniel Goo2, Bokyo N maidy3, M K Aneebuddin4 1印度，Jaunpur, V.B.S. Purvanchal大学生物技术系2，美国，Memphis大学，生物医学工程系3，乌克兰，Uzhhorod国立大学，消化内科系4，印度，泰伦加纳邦，Shadan药学院，药剂学系*信件请寄给Vishnu P. Tripathi, tripatipvishnu@gmail.com
{"title":"New Trends in Interrelation of Infectious Colorectal Cancer with Intestinal Microbiota","authors":"Vishnu P. Tripathi, Daniel Goo, Bokyo N Maidya, M. K. Aneebuddin","doi":"10.33696/gastroenterology.3.038","DOIUrl":"https://doi.org/10.33696/gastroenterology.3.038","url":null,"abstract":"Vishnu P. Tripathi1, Daniel Goo2, Bokyo N Maidya3, M K Aneebuddin4 1Department of Biotechnology, V.B.S. Purvanchal University, Jaunpur, India 2Department of Biomedical Engineering, University of Memphis, USA 3Department of Gastroenterology, Uzhhorod National University, Ukraine 4Department of Pharmaceutics, Shadan College of Pharmacy, Telangana State, India *Correspondence should be addressed to Vishnu P. Tripathi, tripatipvishnu@gmail.com","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84545414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-29DOI: 10.33696/gastroenterology.2.031
Vinícius Lima de Souza Gonçalves, Jonathan Santos Apolonio, Ronaldo Teixeira da Silva Júnior, M. Luísa, Cordeiro Santos, Beatriz Rocha Cuzzuol, Marcel Silva Luz, Fabian Fellipe Bueno Lemos, Hanna Santos Marques, Camilo Santana Silva, Mariana Miranda Sampaio, B. T. Costa, F. Melo
Vinícius Lima de Souza Gonçalves1, Jonathan Santos Apolonio2, Ronaldo Teixeira da Silva Júnior2, Maria Luísa Cordeiro Santos2, Beatriz Rocha Cuzzuol2, Marcel Silva Luz2, Fabian Fellipe Bueno Lemos2, Hanna Santos Marques1, Camilo Santana Silva2, Mariana Miranda Sampaio2, Bruna Teixeira da Costa2, Fabrício Freire de Melo2* 1Universidade Estadual do Sudoeste da Bahia, Vitória da Conquista 45083-900, Bahia, Brazil 2Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Vitória da Conquista 45029-094, Bahia, Brazil *Correspondence should be addressed to Fabrício Freire de Melo; freiremelo@yahoo.com.br
{"title":"Treatment and Drug Resistance to Helicobacter Pylori: A Brief Review","authors":"Vinícius Lima de Souza Gonçalves, Jonathan Santos Apolonio, Ronaldo Teixeira da Silva Júnior, M. Luísa, Cordeiro Santos, Beatriz Rocha Cuzzuol, Marcel Silva Luz, Fabian Fellipe Bueno Lemos, Hanna Santos Marques, Camilo Santana Silva, Mariana Miranda Sampaio, B. T. Costa, F. Melo","doi":"10.33696/gastroenterology.2.031","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.031","url":null,"abstract":"Vinícius Lima de Souza Gonçalves1, Jonathan Santos Apolonio2, Ronaldo Teixeira da Silva Júnior2, Maria Luísa Cordeiro Santos2, Beatriz Rocha Cuzzuol2, Marcel Silva Luz2, Fabian Fellipe Bueno Lemos2, Hanna Santos Marques1, Camilo Santana Silva2, Mariana Miranda Sampaio2, Bruna Teixeira da Costa2, Fabrício Freire de Melo2* 1Universidade Estadual do Sudoeste da Bahia, Vitória da Conquista 45083-900, Bahia, Brazil 2Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Vitória da Conquista 45029-094, Bahia, Brazil *Correspondence should be addressed to Fabrício Freire de Melo; freiremelo@yahoo.com.br","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75576852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-29DOI: 10.33696/gastroenterology.2.033
Daniel Garrido, Peter D Block, Selena Lin, D. Halegoua-DeMarzio, H. Hann
Daniel Garrido1, Peter Block1, Selena Lin2, Dina Halegoua-DeMarzio3, Hie-Won Hann3* 1Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA 2JBS Science Inc., Doylestown, PA, 18902, USA 3Liver Disease Prevention Center, Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA *Correspondence should be addressed to Hie-Won Hann; hie-won.hann@jefferson.edu
Daniel Garrido1, Peter Block1, Selena Lin2, Dina Halegoua-DeMarzio3, Hie-Won han3 * 1美国费城托马斯·杰斐逊大学医院医学部，宾夕法尼亚州19107;jbs Science Inc.，宾夕法尼亚州多耶尔斯敦，18902;美国费城托马斯·杰斐逊大学医院肝脏疾病预防中心，消化内科和肝脏内科，宾夕法尼亚州19107;hie-won.hann@jefferson.edu
{"title":"Survival Disparity Between Antiviral-Treated and Antiviral-Naïve Patients Who Develop Their First HBV-Associated Hepatocellular Carcinoma","authors":"Daniel Garrido, Peter D Block, Selena Lin, D. Halegoua-DeMarzio, H. Hann","doi":"10.33696/gastroenterology.2.033","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.033","url":null,"abstract":"Daniel Garrido1, Peter Block1, Selena Lin2, Dina Halegoua-DeMarzio3, Hie-Won Hann3* 1Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA 2JBS Science Inc., Doylestown, PA, 18902, USA 3Liver Disease Prevention Center, Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA *Correspondence should be addressed to Hie-Won Hann; hie-won.hann@jefferson.edu","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81471606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-29DOI: 10.33696/gastroenterology.2.032
J. Lopera, Ryan Bitar, J. Walker, James Elliott, Katie Strychalski, Harrison Pollard, A. Dang, Luis, Garza, C. Ortiz, M. Parker, Matthew Z Taon, Partha Mandal, Barrett P. O'Donnell, R. Suri, -. Ho, Y. Song
Jorge E Lopera1*, Ryan Bitar2, John Walker1, James Elliott3, Katie Strychalski3, Harrison Pollard2, Annie Dang2, Luis Garza2, Carlos Ortiz1, Matthew Parker1, Matthew Z Taon1, Partha Mandal1, Barrett O’Donnell1, Rajeev Suri1, HoYoung Song1* 1Department of Radiology, UT Health San Antonio, USA 2Long School of Medicine, UT Health San Antonio, USA 3Department of Lab Animal Resources, UT Health San Antonio, USA *Correspondence should be addressed to Jorge E Lopera; Lopera@uthscsa.edu
Jorge E Lopera1*， Ryan Bitar2, John Walker1, James Elliott3, Katie Strychalski3, Harrison pollar2, Annie Dang2, Luis garz2, Carlos Ortiz1, Matthew Parker1, Matthew Z Taon1, Partha Mandal1, Barrett O 'Donnell1, Rajeev sur1, HoYoung Song1* 1美国圣安东尼奥德克萨斯大学健康中心放射科2美国圣安东尼奥德克萨斯大学健康中心朗医学院3美国圣安东尼奥德克萨斯大学健康中心实验动物资源系*通信地址:Jorge E Lopera;Lopera@uthscsa.edu
{"title":"Creation of an Ex-vivo Transjugular Intrahepatic Portosystemic Shunt (TIPS) Training Model Using a Perfused Non-cirrhotic Porcine Liver","authors":"J. Lopera, Ryan Bitar, J. Walker, James Elliott, Katie Strychalski, Harrison Pollard, A. Dang, Luis, Garza, C. Ortiz, M. Parker, Matthew Z Taon, Partha Mandal, Barrett P. O'Donnell, R. Suri, -. Ho, Y. Song","doi":"10.33696/gastroenterology.2.032","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.032","url":null,"abstract":"Jorge E Lopera1*, Ryan Bitar2, John Walker1, James Elliott3, Katie Strychalski3, Harrison Pollard2, Annie Dang2, Luis Garza2, Carlos Ortiz1, Matthew Parker1, Matthew Z Taon1, Partha Mandal1, Barrett O’Donnell1, Rajeev Suri1, HoYoung Song1* 1Department of Radiology, UT Health San Antonio, USA 2Long School of Medicine, UT Health San Antonio, USA 3Department of Lab Animal Resources, UT Health San Antonio, USA *Correspondence should be addressed to Jorge E Lopera; Lopera@uthscsa.edu","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89652372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-29DOI: 10.33696/gastroenterology.2.035
Camilo Santana Silva, Ronaldo Teixeira da Silva Júnior, Luana Kauany de Sá Santos, Jonathan Santos Apolonio, B. T. Costa, Beatriz Rocha Cuzzuol, Marcel Silva Luz, F. Melo
Helicobacter pylori (Hp) is characterized as a gram-negative bacterium with microaerophilic metabolism, flagellated and helix-shaped that affects approximately 50% of the world population and, in some regions, this rate can exceed 80% [1,2]. Hp infection is well known to infect the epithelial tissue of the stomach, being involved with development of many stomach diseases, including gastric carcinoma [3,4]. However, less frequently, this bacterium might also be involved in the development of extragastric disorders, such as manifestations in the gastrointestinal tract, except stomach, autoimmune, dermatological, ophthalmic and cardiac diseases, in addition to neurological, respiratory and endocrine diseases [5,6]. The article titled “Helicobacter pylori infection: beyond gastric manifestations” shows these possibilities [7].
{"title":"Extragastric Manifestations of Helicobacter Pylori Infection: A Commentary","authors":"Camilo Santana Silva, Ronaldo Teixeira da Silva Júnior, Luana Kauany de Sá Santos, Jonathan Santos Apolonio, B. T. Costa, Beatriz Rocha Cuzzuol, Marcel Silva Luz, F. Melo","doi":"10.33696/gastroenterology.2.035","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.035","url":null,"abstract":"Helicobacter pylori (Hp) is characterized as a gram-negative bacterium with microaerophilic metabolism, flagellated and helix-shaped that affects approximately 50% of the world population and, in some regions, this rate can exceed 80% [1,2]. Hp infection is well known to infect the epithelial tissue of the stomach, being involved with development of many stomach diseases, including gastric carcinoma [3,4]. However, less frequently, this bacterium might also be involved in the development of extragastric disorders, such as manifestations in the gastrointestinal tract, except stomach, autoimmune, dermatological, ophthalmic and cardiac diseases, in addition to neurological, respiratory and endocrine diseases [5,6]. The article titled “Helicobacter pylori infection: beyond gastric manifestations” shows these possibilities [7].","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88774001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-29DOI: 10.33696/gastroenterology.2.034
Polina Gaisinskaya, Zed O Seedat, S. Patino, Navneet Kaur, O. Hernández, Eric Abkian, Jamie, Fabricant, M. Azhar, M. DeDonno, Nabil Benhayoun
Polina Gaisinskaya1*, Zed Seedat1, Sanja Patino1, Navneet Kaur1,3, Oscar L. Hernandez1, Eric Abkian1, Jamie Fabricant1, Mishah Azhar1, Michael A. DeDonno2, Nabil Benhayoun1 1Department of Internal Medicine, Florida Atlantic University, Boca Raton, FL, USA 2Division of Educational Leadership and Research Methodology, Florida Atlantic University, Boca Raton, FL, USA 3Pulmonary and Critical Care Medicine, University of Southern California, CA, USA *Correspondence should be addressed to Polina Gaisinskaya; pgaisinskaya@health.fau.edu
Polina gaisinskay1 *， Zed Seedat1, Sanja Patino1, Navneet Kaur1,3, Oscar L. Hernandez1, Eric Abkian1, Jamie Fabricant1, Mishah Azhar1, Michael A. DeDonno2, Nabil Benhayoun1 1佛罗里达大西洋大学内科学系，美国佛罗里达州博卡拉顿2佛罗里达大西洋大学教育领导与研究方法学部，美国佛罗里达州博卡拉顿3南加州大学肺与重症监护医学，加利福尼亚州美国*信件应寄给Polina Gaisinskaya;pgaisinskaya@health.fau.edu
{"title":"The Inappropriate Use of Proton Pump Inhibitors: An Internal Medicine Residency Clinics Effort to Deprescribe","authors":"Polina Gaisinskaya, Zed O Seedat, S. Patino, Navneet Kaur, O. Hernández, Eric Abkian, Jamie, Fabricant, M. Azhar, M. DeDonno, Nabil Benhayoun","doi":"10.33696/gastroenterology.2.034","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.034","url":null,"abstract":"Polina Gaisinskaya1*, Zed Seedat1, Sanja Patino1, Navneet Kaur1,3, Oscar L. Hernandez1, Eric Abkian1, Jamie Fabricant1, Mishah Azhar1, Michael A. DeDonno2, Nabil Benhayoun1 1Department of Internal Medicine, Florida Atlantic University, Boca Raton, FL, USA 2Division of Educational Leadership and Research Methodology, Florida Atlantic University, Boca Raton, FL, USA 3Pulmonary and Critical Care Medicine, University of Southern California, CA, USA *Correspondence should be addressed to Polina Gaisinskaya; pgaisinskaya@health.fau.edu","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90457032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-05DOI: 10.33696/gastroenterology.2.027
Stephanie Göing, K. Jung
Viable but nonculturable (VBNC) bacteria are deeply dormant phenotypic variants that are characterized by a loss of culturability in conventional culture media, yet retain some viability markers [1]. Thus, low metabolic activity, nutrient uptake, membrane integrity, and respiration are all detectable in these dormant cells. In 1982, the VBNC state was first described for Escherichia coli and Vibrio cholerae [2]. Shortly afterwards, VBNC Salmonella enteriditis were found to regain culturability when placed under favourable conditions [3]. Since then, more than 100 bacterial species (including approximately 30 gastrointestinal bacteria) and some fungi have been reported to enter the VBNC state (see Dong et al. [4] and Li et al. [5] for excellent reviews). Among them are many food-borne, toxin-producing bacteria, such as Aeromonas hydrophila, Bacillus cereus, Campylobacter jejuni, E. coli O157:H7, Lactobacillus acetotolerans, Listeria monocytogenes, S. enterica, Shigella flexneri, V. cholerae, but also probiotic bacteria, such as Bifidobacterium animalis, Bf. longum and Bf. lactis [6].
可存活但不可培养(VBNC)细菌是一种深度休眠的表型变异，其特征是在传统培养基中丧失可培养性，但仍保留一些生存能力标记[1]。因此，在这些休眠细胞中可以检测到低代谢活性、营养摄取、膜完整性和呼吸作用。1982年，首次报道了大肠杆菌和霍乱弧菌的VBNC状态[2]。不久之后，发现在有利条件下，VBNC肠炎沙门氏菌可恢复培养[3]。从那时起，已有超过100种细菌(包括大约30种胃肠道细菌)和一些真菌被报道进入VBNC状态(优秀评论见Dong et al.[4]和Li et al.[5])。其中有许多食源性产毒细菌，如嗜水气单胞菌、蜡样芽孢杆菌、空肠弯曲杆菌、大肠杆菌O157:H7、醋酸耐受乳杆菌、单核增生李斯特菌、肠链球菌、福氏志贺氏菌、霍乱弧菌等，也有益生菌，如动物双歧杆菌、Bf。longum和Bf。lactis[6]。
{"title":"Viable but Nonculturable Gastrointestinal Bacteria and Their Resuscitation","authors":"Stephanie Göing, K. Jung","doi":"10.33696/gastroenterology.2.027","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.027","url":null,"abstract":"Viable but nonculturable (VBNC) bacteria are deeply dormant phenotypic variants that are characterized by a loss of culturability in conventional culture media, yet retain some viability markers [1]. Thus, low metabolic activity, nutrient uptake, membrane integrity, and respiration are all detectable in these dormant cells. In 1982, the VBNC state was first described for Escherichia coli and Vibrio cholerae [2]. Shortly afterwards, VBNC Salmonella enteriditis were found to regain culturability when placed under favourable conditions [3]. Since then, more than 100 bacterial species (including approximately 30 gastrointestinal bacteria) and some fungi have been reported to enter the VBNC state (see Dong et al. [4] and Li et al. [5] for excellent reviews). Among them are many food-borne, toxin-producing bacteria, such as Aeromonas hydrophila, Bacillus cereus, Campylobacter jejuni, E. coli O157:H7, Lactobacillus acetotolerans, Listeria monocytogenes, S. enterica, Shigella flexneri, V. cholerae, but also probiotic bacteria, such as Bifidobacterium animalis, Bf. longum and Bf. lactis [6].","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"10 13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80643047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-05DOI: 10.33696/gastroenterology.2.030
R. Teschke
As the new editor-in-chief of Archives of Gastroenterology Research (AGR) I cordially welcome all current readers of AGR and future contributors to AGR. Together with my editorial team of AGR we encourage scientists and clinicians involved in the care of patients with gastrointestinal diseases to submit their interesting reports to AGR with the aim to be published following fair evaluation by external peer reviewers. Gastroenterology with its broad range of subsegments and involving many organs is a fascinating and challenging area of research and clinical aspects. Highly appreciated are controversial issues, which help stimulate discussions under experts in the field, in line with the view that Gastroenterology shares features of a learning system. Welcomed are also non–controversial reports as long as they provide new aspects rather than confirmatory data.
{"title":"Archives of Gastroenterology Research: A Message from Prof. Dr. Rolf Teschke (Editor-in-Chief)","authors":"R. Teschke","doi":"10.33696/gastroenterology.2.030","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.030","url":null,"abstract":"As the new editor-in-chief of Archives of Gastroenterology Research (AGR) I cordially welcome all current readers of AGR and future contributors to AGR. Together with my editorial team of AGR we encourage scientists and clinicians involved in the care of patients with gastrointestinal diseases to submit their interesting reports to AGR with the aim to be published following fair evaluation by external peer reviewers. Gastroenterology with its broad range of subsegments and involving many organs is a fascinating and challenging area of research and clinical aspects. Highly appreciated are controversial issues, which help stimulate discussions under experts in the field, in line with the view that Gastroenterology shares features of a learning system. Welcomed are also non–controversial reports as long as they provide new aspects rather than confirmatory data.","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89769195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-05DOI: 10.33696/gastroenterology.2.028
N. Javitt
How medications whose major biologic effect is to reduce bile acid synthesis favorably affect the course of a variety of cholestatic and metabolic liver diseases is not immediately apparent. Also, the most frequently used plasma biomarkers for evaluating benefit, alkaline phosphatase and conjugated bilirubin [1], provide different information. The former may be misleading with respect to the course of the disease and therefore it is important to focus on the pathophysiologic basis for its use.
{"title":"Obeticholic Acid, FXR Agonists, Liver Disease and Plasma Biomarkers","authors":"N. Javitt","doi":"10.33696/gastroenterology.2.028","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.028","url":null,"abstract":"How medications whose major biologic effect is to reduce bile acid synthesis favorably affect the course of a variety of cholestatic and metabolic liver diseases is not immediately apparent. Also, the most frequently used plasma biomarkers for evaluating benefit, alkaline phosphatase and conjugated bilirubin [1], provide different information. The former may be misleading with respect to the course of the disease and therefore it is important to focus on the pathophysiologic basis for its use.","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78666402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-05DOI: 10.33696/gastroenterology.2.026
Lolwa N Al-Obaid, Rebecca Roediger, M. Lisker‐Melman
This commentary further expands on the topics touched on in the study “Maternal knowledge of the risk of vertical transmission and offspring acquisition of hepatitis B”. We discuss in detail hepatitis B in pregnancy, with a focus on screening, treatment and vaccination of new-borns. We also examine why the global coverage of hepatitis B vaccination at birth is astoundingly low, despite our knowledge of its efficacy. Then, we provide insight into the barriers to providing appropriate screening in the USA, as well as the importance of maternal education in the fight against hepatitis B, particularly with regards to mother to child transmission.
{"title":"Pregnancy and Hepatitis B Immunization: A Commentary on Maternal Knowledge and Vertical Transmission Risks","authors":"Lolwa N Al-Obaid, Rebecca Roediger, M. Lisker‐Melman","doi":"10.33696/gastroenterology.2.026","DOIUrl":"https://doi.org/10.33696/gastroenterology.2.026","url":null,"abstract":"This commentary further expands on the topics touched on in the study “Maternal knowledge of the risk of vertical transmission and offspring acquisition of hepatitis B”. We discuss in detail hepatitis B in pregnancy, with a focus on screening, treatment and vaccination of new-borns. We also examine why the global coverage of hepatitis B vaccination at birth is astoundingly low, despite our knowledge of its efficacy. Then, we provide insight into the barriers to providing appropriate screening in the USA, as well as the importance of maternal education in the fight against hepatitis B, particularly with regards to mother to child transmission.","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80818909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：