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Archives of otolaryngology--head & neck surgery最新文献

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Tracheal metastasis of lung adenocarcinoma 肺腺癌气管转移
Pub Date : 2022-01-01 DOI: 10.4322/ahns.2022.0014
Nathan Arnaldo Roble Alves, Aloysio Enck Neto, Franthieska Lily Rodrigues Gründmann, K. Foltz, Lucas Spina
A 46-year-old female presented with dyspnea, dysphagia, and throat irritation with a diagnosis of tracheal metastasis resulting from a previously resected lung adenocarcinoma. Upper airway metastasis has a poor prognosis and is rarely observed. The clinical presentation manifests with cough and hemoptysis in most cases. Treatment includes surgical metastatic removal associated with combined radiotherapy and chemotherapy
患者46岁,女性,以呼吸困难、吞咽困难和咽喉刺激为主要表现,诊断为先前切除的肺腺癌引起的气管转移。上呼吸道转移预后差,很少观察到。临床表现以咳嗽和咯血为主。治疗包括手术转移性切除,联合放疗和化疗
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引用次数: 0
COVID-19 and cervical lymphadenopathy COVID-19和宫颈淋巴结病
Pub Date : 2022-01-01 DOI: 10.4322/ahns.2022.0003
Ana Cecilia C. Almeida de Moura, Fátima C. Mendes de Matos
COVID-19 has brought a number of diseases secondary to viral infection, and there have been several reports on clinical manifestations related to vaccination. One of the effects reported in the literature, either related to the disease or to the vaccines, is the occurrence of cervical lymphadenopathy, which can result in a misleading differential diagnosis of malignant neoplasms. It is important that the specialist be aware of this differential diagnosis for an accurate management of cases.
COVID-19带来了许多病毒感染的继发性疾病,并且已经有一些与疫苗接种相关的临床表现的报道。文献中报道的影响之一,要么与疾病有关,要么与疫苗有关,是宫颈淋巴结病的发生,这可能导致恶性肿瘤的误导性鉴别诊断。重要的是,专家要意识到这种鉴别诊断的准确管理的情况下。
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引用次数: 0
Evaluation of oncological outcomes in patients with oral cavity cancer treated in a lowvolume hospital 小容量医院治疗口腔癌患者的肿瘤预后评价
Pub Date : 2022-01-01 DOI: 10.4322/ahns.2022.0010
Sara de Souza Bettioli, A. Graciano, Ana Lavratti Borga, C. Fischer
Introduction: Oral cavity cancer (OCC) is one of the 10 most common types of tumors in the world. Surgical resection is the most indicated initial treatment, followed by adjuvant therapy, depending on tumor stage. A few studies have suggested that patients treated in high-volume hospitals present better oncologic outcomes; however, particularly in continental countries, some patients are treated in regional hospitals. Objective: To evaluate the results of OCC patients treated in low-volume regional hospitals. Methods: This is a retrospective longitudinal study conducted with patients diagnosed with OCC and operated on in a low-volume hospital between January 2003 and December 2018. Results: 174 patients with OCC were treated at the institution - an average of 11 patients/year. The most common tumor location was the tongue (48.2%), followed by the lip (18.2%). Squamous cell carcinomas were the most frequent (94.7% of patients). Adjuvant radiotherapy and chemotherapy were performed in 46.7 and 31.9% of patients, respectively. Almost 21% of patients had some postoperative complication. Specific survival of 62.6% and global survival of 58.2% after 3 years were similar to the results reported in high-volume centers. Disease-free survival was 45.8% in the same period. Conclusion: Low-volume hospitals qualified for oncological treatments can present outcomes similar to those of high-volume centers, and are thus a regional option for patients with OCC.
口腔癌(Oral Oral cancer, OCC)是世界上最常见的10种肿瘤之一。手术切除是最适合的初始治疗方法,然后根据肿瘤分期进行辅助治疗。一些研究表明,在大容量医院接受治疗的患者有更好的肿瘤预后;但是,特别是在大陆国家,一些病人在区域医院接受治疗。目的:评价小容量地区医院治疗OCC患者的效果。方法:对2003年1月至2018年12月在一家小容量医院诊断为OCC并进行手术的患者进行回顾性纵向研究。结果:174例OCC患者在该机构接受治疗-平均11例/年。最常见的肿瘤部位是舌头(48.2%),其次是嘴唇(18.2%)。鳞状细胞癌最为常见(占94.7%)。辅助放疗和化疗分别占46.7%和31.9%。近21%的患者有术后并发症。3年后的特异性生存率为62.6%,总体生存率为58.2%,与大容量中心报告的结果相似。同期无病生存率为45.8%。结论:具有肿瘤治疗资质的小容量医院可以提供与大容量中心相似的结果,因此是OCC患者的区域性选择。
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引用次数: 0
Otogenic Lemierre’s Syndrome With Bilateral Metastatic Pneumonia: Report of an Unusual Case in a Male 耳源性Lemierre综合征合并双侧转移性肺炎:一罕见男性病例报告
Pub Date : 2022-01-01 DOI: 10.24983/scitemed.aohns.2022.00158
P. Y. Fong, Y. M. Chan, Joy Tang
Lemierre’s syndrome manifests as thrombophlebitis of the internal jugular vein caused by anaerobic bacteria, particularly Fusobacterium necrophorum [1]. In general, Lemierre's syndrome occurs following oropharyngeal infections, while cases of otogenic Lemierre's syndrome precipitated by acute otitis media and mastoiditis have been reported in pediatric patients [2], but such cases are rare in adults. Lemierre's syndrome can also be a life-threatening condition owing to the possibility of metastatic infection affecting many organ systems and the consequential risk of severe sepsis [3]. Our case report describes an adult with otogenic Lemierre's syndrome complicated by metastatic severe bilateral pneumonia presenting with atypical symptoms and requiring aggressive surgical and antibiotic treatment.
Lemierre综合征表现为由厌氧菌,尤其是坏死性梭杆菌引起的颈内静脉血栓性炎[1]。一般来说,Lemierre's综合征发生在口咽感染后,而耳源性Lemierre's综合征由急性中耳炎和乳突炎诱发的病例在儿科患者中有报道[2],但在成人中罕见。由于转移性感染可能影响许多器官系统以及随之而来的严重败血症风险,Lemierre综合征也可能是一种危及生命的疾病[3]。我们的病例报告描述了一个成人耳源性Lemierre综合征合并转移性严重双侧肺炎,表现为非典型症状,需要积极的手术和抗生素治疗。
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引用次数: 0
Impact of TNM® 8th edition on thyroid cancer retrospective staging TNM®第8版对甲状腺癌回顾性分期的影响
Pub Date : 2022-01-01 DOI: 10.4322/ahns.2022.0006
O. T. Daronch, N. Ahumada
Introduction: Thyroid carcinoma has a global survival close to 97% in 15 years. The 8 th TNM ® has recently been proposed, with changes that include an increase in the cut-off age from 45 to 55 years, a change in the role of microscopic extra-thyroidal tumor invasion (which is no longer considered a criterion for the classification of T3 tumors), and the presence of cervical metastases as a criterion for staging. As a result, a large proportion of patients are transferred to earlier stages. Methods: Retrospective descriptive cross-sectional study carried out through analysis of the medical records of patients undergoing thyroidectomy at HC-UFPR from January 2014 to December 2017. Inclusion criteria were patients with a postoperative pathological anatomic diagnosis of well-differentiated thyroid carcinoma (DTC) who underwent primary surgery in the study period. Results: 197 patients underwent thyroidectomy during the period considered, 58 with thyroid neoplasia and 34 with DTC. Eight patients had lymph node metastasis, five (14.70%) as N1a and three (8.83%) as N1b. Of the total sample, six (12.5%) patients presented downstaging from the 7 th to the 8 th edition of the TNM ® . One of the re-staged patients had bone metastasis during follow-up and died during surgery to correct a pathological fracture. Conclusion: In this study sample, the update of the TNM ® in its 8 th edition resulted in the downstaging of six (12.5%) patients with DTC. A longer follow-up and a larger sample are necessary to correctly assess the impact of this change on patient prognosis.
简介:甲状腺癌在15年内的全球生存率接近97%。最近提出了第8个TNM®,其变化包括将截止年龄从45岁增加到55岁,改变了显微镜下甲状腺外肿瘤侵袭的作用(这不再被认为是T3肿瘤分类的标准),并将宫颈转移的存在作为分期标准。因此,很大一部分患者被转移到早期阶段。方法:对2014年1月至2017年12月在HC-UFPR行甲状腺切除术患者的病历进行回顾性描述性横断面研究。纳入标准是术后病理解剖诊断为高分化甲状腺癌(DTC)并在研究期间接受了原发性手术的患者。结果:197例患者行甲状腺切除术,其中甲状腺瘤58例,DTC 34例。8例患者有淋巴结转移,N1a 5例(14.70%),N1b 3例(8.83%)。在总样本中,6例(12.5%)患者从第7版到第8版TNM®出现了分期下降。其中一名重新分期的患者在随访期间发生骨转移,并在手术纠正病理性骨折期间死亡。结论:在本研究样本中,TNM®第8版的更新导致6例(12.5%)DTC患者的分期降低。为了正确评估这种变化对患者预后的影响,需要更长的随访时间和更大的样本。
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引用次数: 0
Adenoid cystic carcinoma in atypical site: case report 非典型部位腺样囊性癌1例
Pub Date : 2022-01-01 DOI: 10.4322/ahns.2022.0008
Amanda Rios Sampaio, Júlia Rusch Pinto Vasconcelos, Julyana Bastos Santana, Luis Filipe Alves Kian, D. O. Lopes
Adenoid cystic carcinoma (ACC) is a rare form of malignant neoplasm of the salivary glands, with slow growth and late symptoms. One of the challenges presented by this tumor is its high rate of metastasis, with tropism to the nervous system, liver and bones. Treatment is based on surgical resection of the tumor, radiotherapy, and chemotherapy – it varies depending on the condition of each patient. In view of the low frequency of ACC, this study aims to report a case of ACC in a female patient, with anatomopathological diagnosis of basaloid cell neoplasm.
腺样囊性癌(ACC)是一种罕见的涎腺恶性肿瘤,生长缓慢,症状较晚。这种肿瘤面临的挑战之一是它的高转移率,倾向于神经系统,肝脏和骨骼。治疗是基于手术切除肿瘤,放疗和化疗-它取决于每个病人的情况。鉴于ACC的发病率较低,本研究报告1例女性ACC患者,解剖病理诊断为基底细胞瘤。
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引用次数: 0
Knowledge about head and neck cancer among adolescents 青少年对头颈癌的了解
Pub Date : 2022-01-01 DOI: 10.4322/ahns.2022.0009
V. M. Vasconcellos, L. Matos, F. Hojaij, Edevaldo Miguel Alves, Beatriz Martins, Arthur C. Nava
Introduction: The expansion of knowledge about head and neck cancer can provide greater care and the ability to identify risk factors and symptoms of the disease, as well as the incorporation of healthy habits. The younger these concepts are sedimented, the better results will be, making society healthier and more aware. Objective: To assess knowledge about head and neck cancer among adolescents from private schools, aged between 13 and 22 years. Methods: 200 questionnaires were applied among students, about the profile of adolescents and their knowledge about head and neck neoplasms, treatment, and teaching in schools on this topic. The results were analyzed both quantitatively and qualitatively. Results: Only 55 students (29.9%) identified HPV as a risk factor for the disease. 137 students (74.5%) identified the brain as an organ treated by head and neck surgery. As for the therapeutic strategies used for the treatment of neoplasms in the region, only 67 students (36.4%) are aware. On the topic of teaching in schools, 153 students (83.1%) relate to some deficiency in the approach and learning. Conclusion: Knowledge about head and neck cancer is insufficient. It is necessary to introduce in the curriculum basic cancer education in biology classes. The expansion of acquirements about cancer can provide better care and the ability to identify risk factors, initial signs, and symptoms of the disease, as well as the incorporation of healthy habits in families because these students can propagate valid information in their environment.
前言:头颈癌知识的扩展可以提供更好的护理和识别疾病的危险因素和症状的能力,以及纳入健康习惯。这些概念越年轻,结果就越好,使社会更健康,更有意识。目的:了解13 ~ 22岁私立学校青少年头颈癌相关知识。方法:对200名学生进行问卷调查,了解青少年对头颈部肿瘤的了解情况、治疗方法和学校教学情况。结果进行了定量和定性分析。结果:只有55名学生(29.9%)认为HPV是该疾病的危险因素。137名学生(74.5%)认为大脑是通过头颈部手术治疗的器官。对于该地区肿瘤的治疗方法,只有67名(36.4%)学生知道。在学校教学的话题上,153名学生(83.1%)表示在方法和学习方面存在一些不足。结论:对头颈部肿瘤认识不足。在生物课课程中引入肿瘤基础教育是必要的。扩大对癌症的了解可以提供更好的护理和识别疾病的风险因素、初始体征和症状的能力,并将健康习惯纳入家庭,因为这些学生可以在他们的环境中传播有效的信息。
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引用次数: 0
Plugging of a Dehiscent Superior Semicircular Canal Damages the Spiral Ganglion Regardless of the Material Used 无论使用何种材料,封堵开裂的上半规管都会损害螺旋神经节
Pub Date : 2022-01-01 DOI: 10.24983/scitemed.aohns.2022.00160
P. Kwok, O. Gleich, K. Utpatel, C. Bohr, J. Strutz
In canal that After visual verification of successful blockage ABSTRACT Objective: The use of bone wax to plug a dehiscent superior semicircular canal has been found to be associated with poorer hearing outcomes in humans when compared with the use of bone. Animal models showed that plugging the superior or lateral semicircular canal with bone wax caused an inflammatory reaction in the middle ear that was significantly more severe than with bone or Teflon. Damage to the cochlea can lead to alterations in the size, number and density of the spiral ganglion neurons. This study aims to examine potential cochlear damage caused by plugging a dehiscent superior semicircular canal with different materials in gerbils by analyzing the spiral ganglion of the basal cochlear turn. Methods: We used hematoxylin and eosin-stained mid-modiolar paraffin sections from 44 operated ears and 19 non-operated control ears to examine spiral ganglion structures in cochlear cross-sections through the lower basal turn and upper basal turn. We calculated the number of spiral ganglion cells and measured their size. We also measured the area of the Rosenthal's canal and assessed the density of neurons within it. Furthermore, the degree of interstitial edema within the spiral ganglion was assessed. Results: For most of the plugging materials, the main pathological finding following surgery was a loss of spiral ganglion cells predominantly in the lower basal turn. No evidence was found for a shrinkage of spiral ganglion cells or a reduction in spiral ganglion cell density as a result of plugging the superior semicircular canal. Conclusion: The spiral ganglion appears to be more severely damaged in the lower basal turn compared to the upper basal turn for the majority of mate rials used for plugging a dehiscent superior semicircular canal.
【摘要】目的:使用骨蜡封堵开裂的上半圆形椎管与使用骨填塞相比,人类听力结果较差。动物模型显示,用骨蜡堵塞上半规管或外侧半规管引起的中耳炎症反应明显比用骨或聚四氟乙烯严重。耳蜗的损伤会导致螺旋神经节神经元的大小、数量和密度的改变。本研究旨在通过分析沙鼠耳蜗基底转螺旋神经节,探讨不同材料封堵开裂的上半规管对耳蜗的潜在损伤。方法:采用苏木精染色和伊红染色的耳蜗中模孔石蜡切片,分别对44只手术耳和19只非手术耳进行下基底转和上基底转耳蜗横切面螺旋神经节结构的观察。我们计算了螺旋神经节细胞的数量并测量了它们的大小。我们还测量了罗森塔尔管的面积,并评估了其中的神经元密度。进一步,评估螺旋神经节间质水肿程度。结果:对于大多数堵塞材料,手术后的主要病理表现是螺旋神经节细胞的丢失,主要是在下基转。没有证据表明螺旋神经节细胞的收缩或螺旋神经节细胞密度的减少是堵塞上半规管的结果。结论:在大多数用于封堵开裂的上半规管的材料中,螺旋神经节在基底下匝比基底上匝损伤更严重。
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引用次数: 0
Combination of surgical techniques and reconstructive devices as an alternative treatment after fibula free flap mandibular reconstruction failure: a case report 腓骨游离皮瓣下颌骨重建失败后手术技术与重建装置的结合治疗1例
Pub Date : 2022-01-01 DOI: 10.4322/ahns.2022.0002
Beatrice Mitye Ogusco, Luiza Miguel Simonetti, André Sakima Serrano, L. C. Ishida, R. Tutihashi, D. Carlucci, Sérgio Gonçalves
Loss of mandibular continuity and functionality in cancer patients undergoing extensive mandible resections is challenging. In these situations, the gold standard treatment is fibula free flap reconstruction. The major challenge occurs when there is a failure of the transplanted fibula. Here we report the case of a patient who underwent right hemimandibulectomy with disarticulation and immediate mandibular reconstruction with a fibula free flap. Subsequently, the flap viability was lost, and there was necrosis of the transplanted bone segment in the short-term follow-up. Considering the best form of rehabilitation for the patient, minimizing the risks of loss and optimizing the reconstructive quality, we opted to install a customized prosthesis including a condyle-cavity joint component associated with a new free flap and subsequent rehabilitation of the dental occlusion with an implant-supported fixed prosthesis.
在接受广泛下颌骨切除术的癌症患者中,下颌连续性和功能的丧失是具有挑战性的。在这种情况下,金标准治疗是腓骨游离皮瓣重建。主要的挑战发生在腓骨移植失败的时候。在这里,我们报告的情况下,病人接受了右半下颌切除术与脱臼和立即下颌骨重建腓骨游离皮瓣。术后短期随访,皮瓣丧失活力,移植骨段出现坏死。考虑到患者的最佳康复形式,最大限度地减少损失的风险并优化重建质量,我们选择安装一个定制的假体,包括一个与新的自由皮瓣相关的髁-腔关节组件,随后使用种植体支持的固定假体对牙合进行康复。
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引用次数: 0
Benign thyroid diseases: a public health problem aggravated in times of COVID-19 pandemic 良性甲状腺疾病:COVID-19大流行期间加剧的公共卫生问题
Pub Date : 2022-01-01 DOI: 10.4322/ahns.2022.0007
G. Melo, A. Gonçalves
1Universidade Federal de São Paulo, Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, São Paulo, SP, Brasil 2Hospital da Beneficência Portuguesa de São Paulo (HBP), Departamento de Cirurgia de Cabeça e Pescoço, São Paulo, SP, Brasil 3Faculdade de Medicina da Santa Casa de São Paulo, Hospital da Santa Casa de São Paulo, Departamento de Cirurgia de Cabeça e Pescoço, São Paulo, SP, Brasil
圣保罗1联邦大学,专业部门和头颈部手术、圣保罗、SP、巴西圣保罗2葡萄牙慈善医院(bph),头部和颈部手术部、巴西,圣保罗高层3医学院圣家的圣保罗,圣保罗圣家的医院手术部的头和脖子上,巴西的圣保罗,
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引用次数: 0
期刊
Archives of otolaryngology--head & neck surgery
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