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Substance Use and Mental Health Responses to COVID-19 among Rural Adolescents 农村青少年对COVID-19的物质使用和精神卫生反应
Pub Date : 2023-06-30 DOI: 10.29011/2575-825x.100274
L. Monico, K. O’grady, J. Gryczynski, Kaitlyn, Garrison, Tyler Ross, M. Terplan, S. Mitchell
Purpose: This analysis provides a cross-sectional examination of adolescent mental health and substance use, to explore whether COVID-19 related stressors had an impact on substance use. Methods: This analysis examines data from 249 adolescents (aged 12-17 years) gathered between April 2020-April 2021. Adolescents completed a one-time survey assessing COVID-19-related stressors (CDC COVID-19 question bank), anxiety (GAD-7), depression (PHQ-9)
目的:本分析提供了青少年心理健康和物质使用的横断面检查,探讨与COVID-19相关的压力源是否对物质使用产生影响。方法:本分析分析了2020年4月至2021年4月期间收集的249名青少年(12-17岁)的数据。青少年完成了一项一次性调查,评估与COVID-19相关的压力源(CDC COVID-19题库)、焦虑(GAD-7)、抑郁(PHQ-9)。
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引用次数: 0
Accidental Paracetamol Poisoning: A Neonatal Case Report 意外扑热息痛中毒:一个新生儿病例报告
Pub Date : 2023-06-28 DOI: 10.29011/2575-825x.100273
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引用次数: 0
The Effect of Lingual Frenectomy on Pain Relief during Breastfeeding 舌系带切除术对母乳喂养疼痛缓解的影响
Pub Date : 2023-06-20 DOI: 10.29011/2575-825x.100272
Adriana Ferreira Marques, Alexandra Silva Ferreira, Sofia Sousa-Santos, Primavera Sousa-Santos, Teresa Vale
Difficulty in breastfeeding is a very frequent complaint in mothers to breastfeed. One of the difficulties is the presence of pain
母乳喂养困难是母乳喂养母亲经常抱怨的问题。困难之一是痛苦的存在
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引用次数: 0
IGF-2 and IGFBP-3 in Pregnancies Complicated by PIH and IUGR IGF-2和IGFBP-3在妊高征和妊高征合并妊娠中的作用
Pub Date : 2023-06-09 DOI: 10.29011/2575-825x.100271
Patrycja K Gazy, S. Marciniak, Helena, B. Mazur
Objectives: Around 15% of pregnant women develop pregnancy associated complications that increase the risk of maternal and fetal morbidity and mortality. The most common pregnancy complications are: pregnancy induced hypertension (PIH) and intrauterine growth restriction (IUGR). Insulin-like growth factors (IGFs) were proven to play an essential role in placenta growth, fetus development and modifications of their metabolism. The aim of this study was to compare the concentration of IGF-2 and IGF binding protein-3 (IGFBP-3) in pregnancies complicated by PIH, IUGR and pregnacies complicated by both PIH and IUGR. Methods: 84 pairs of pregnant women and their newborns were divided into four cohorts: eutrophic newborns from pregnancies complicated by PIH, newborns who met the criteria for IUGR, newborns from pregnancies complicated by both PIH and IUGR and control group. IGF-2 and IGFBP-3 serum levels in umbilical cord blood were measured in each group by immunoenzymatic method. The obtain date were analised statistically using STATISCTICA statistical package. Results: IGF-2 serum levels per body surface area were found to be higher in neonates with IUGR (in both subgroups of pregnancies: complicated and uncomplicated by PIH). On the other hand, no differences in IGFBP-3 concentration between cohorts was found. Conclusion: Futher studies are essential to investigate whether changes in growth hormone secretion are the cause or the reasult of the ongoing adaptation to adverse conditions of intrauterine environment.
目的:约15%的孕妇出现妊娠相关并发症,增加了孕产妇和胎儿发病率和死亡率的风险。最常见的妊娠并发症是:妊高征(PIH)和宫内生长受限(IUGR)。胰岛素样生长因子(IGFs)已被证明在胎盘生长、胎儿发育及其代谢的改变中起重要作用。本研究的目的是比较合并PIH、IUGR和合并PIH、IUGR的妊娠中IGF-2和IGF结合蛋白-3 (IGFBP-3)的浓度。方法:将84对孕妇及其新生儿分为妊娠合并PIH的富营养化新生儿、符合IUGR标准的新生儿、合并PIH和IUGR的新生儿和对照组。免疫酶法测定各组脐带血IGF-2、IGFBP-3血清水平。使用statissctica统计软件包对所得数据进行统计分析。结果:发现IUGR新生儿的每体表面积IGF-2血清水平较高(在妊娠的两个亚组中:合并和未合并PIH)。另一方面,各组间IGFBP-3浓度没有差异。结论:生长激素分泌的变化是持续适应宫内不利环境的原因还是结果,需要进一步研究。
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引用次数: 0
Congenital Scoliosis Associated with Tobacco and Illicit Substance Use 先天性脊柱侧凸与烟草和非法药物使用有关
Pub Date : 2023-06-05 DOI: 10.29011/2575-825x.100270
C. Brown, A. Campbell, Jessica B. Beavers, M. Baber, Clare C. Nesmith, G. White
Congenital scoliosis is a complex spinal deformity that arises during fetal development. It is often associated with other congenital anomalies, such as those found in VACTERL syndrome, which includes vertebral anomalies, anal atresia, cardiac defects, tracheoesophageal fistula, renal anomalies, and limb abnormalities. This case report presents a unique case of congenital scoliosis associated with VACTERL syndrome and explores the impact of substance use during pregnancy
先天性脊柱侧凸是一种复杂的脊柱畸形,发生在胎儿发育期间。它通常与其他先天性异常相关,如VACTERL综合征,包括椎体异常、肛门闭锁、心脏缺陷、气管食管瘘、肾脏异常和肢体异常。本病例报告提出了一个独特的先天性脊柱侧凸与VACTERL综合征相关的病例,并探讨了怀孕期间物质使用的影响
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引用次数: 0
Improving Pediatric Psychiatric Hospitalization Outcomes through Symptom-Targeted Assessments 通过针对症状的评估改善儿科精神科住院治疗结果
Pub Date : 2023-06-05 DOI: 10.29011/2575-825x.100269
D. Sperbeck
Background: Inpatient psychiatric treatment for pediatric populations must be undertaken carefully in order to minimize stigmatization, developmental and social delays, and alienation from family and peers. As such, maximizing pediatric psychiatric hospitalization efficacy must be a priority for clinical and administrative staff. Objectively derived treatment plans focusing on symptom-targeted assessments can improve treatment efficacy [1]
背景:儿科人群的住院精神病治疗必须谨慎进行,以尽量减少污名化,发展和社会延迟,以及与家庭和同龄人的疏远。因此,最大限度地提高儿童精神病学住院疗效必须是临床和行政人员的优先事项。以症状为重点的客观衍生治疗方案可提高治疗效果[1]
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引用次数: 0
Spectrum of Congenital Myenteric Hypoganglionosis and Aganglionosis in Patients with Waardenburg Syndrome Type 4 Waardenburg综合征4型患者先天性肌enteric神经节减少症和Aganglionosis的谱
Pub Date : 2023-06-02 DOI: 10.29011/2575-825x.100268
K. Murray, Kahleb Graham, S. Szabo, S. Kocoshis, Lev, Dorfman, A. Kaul
Introduction: Waardenburg Syndrome (WS) is a rare, genetically and phenotypically heterogeneous disorder caused by abnormal migration or differentiation of neural crest cells during embryonic development. WS is classified into four types: WS Type 1 (WS1), WS2, WS3
Waardenburg综合征(WS)是一种罕见的遗传和表型异质性疾病,由胚胎发育过程中神经嵴细胞的异常迁移或分化引起。WS分为四种类型:WS1、WS2、WS3
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引用次数: 0
Mechanical Ventilation and Secondary Infections in Infants with Bronchiolitis 毛细支气管炎婴儿机械通气与继发感染
Pub Date : 2023-05-29 DOI: 10.29011/2575-825x.100266
N. Anvaripour, Ngozichukwuka Agu, Kenechukwu Aronu, Rishi Ramachandruni, S. Raj
Background: In this study we evaluated mechanical ventilation (MV) and Secondary bacterial infections (SBI) in infants with bronchiolitis. Methods: This is a retrospective chart review analyzing the MV course, complications and SBI in bronchiolitis infants. Descriptive statistics and unpaired t-tests were used to compare the data. Results: There were 32 infants with mean age of 2.2 ± 2.1 months, 56% were premature, 17 (53%) had Respiratory syncytial virus (RSV) and no mortality. Pressure control (PC) ventilation was used in 22 (68%) and volume control (VC) in10 (32%) patients. Initial Peak inspiratory pressures (PIP) were 26 ± 5 cm of H 2 O, Compliance was 0.4 ±0.1 ml/kg/cm of H 2 O, oxygen requirement was 67 ± 26%. Average duration of ventilation was 3.9 ±2.6 days. PIP was lower in PC compared to VC ventilation (24 ± 4 versus 28 ± 5 cm of H 2 O, with equivalent tidal volumes, p =0.04). MV duration was longer in preterm infants (5 ± 3.3 versus 2.9 ± 1.1 days, p =0.02). and in infants with poly-viral infections (5.3 ± 4.5 versus 3.4 ±1.6 days, p =0.09). Eighteen patients (56%) had SBI. These had longer MV compared to infants with no SBI (4.8 ± 3.1 versus 2.6 ±1.3 days, p =0.017). Hemophilus influenzae (31%), Moraxella catarrhalis (22%), Streptococcus pneumoniae (18%) were common organisms. Conclusion: Average duration of MV in bronchiolitis infants is 4 days with low mortality with 56% incidence of SBI. Prematurity, poly-viruses and SBI are risk factors for longer duration of MV.
背景:在这项研究中,我们评估了毛细支气管炎婴儿机械通气(MV)和继发性细菌感染(SBI)。方法:回顾性分析毛细支气管炎患儿的MV病程、并发症及SBI。采用描述性统计和非配对t检验对数据进行比较。结果:32例患儿平均年龄2.2±2.1个月,早产儿56%,呼吸道合胞病毒17例(53%),无死亡。22例(68%)采用压力控制(PC)通气,10例(32%)采用容积控制(VC)通气。初始峰值吸气压力(PIP)为26±5 cm h2o,顺应性为0.4±0.1 ml/kg/cm h2o,需氧量为67±26%。平均通气时间为3.9±2.6 d。与VC通气相比,PC通气的PIP较低(24±4 vs 28±5 cm h2o,潮汐量相等,p =0.04)。早产儿的MV持续时间更长(5±3.3天和2.9±1.1天,p =0.02)。多病毒感染婴儿(5.3±4.5天和3.4±1.6天,p =0.09)。18例患者(56%)有SBI。与没有SBI的婴儿相比,这些婴儿的MV更长(4.8±3.1 vs 2.6±1.3天,p =0.017)。流感嗜血杆菌(31%)、卡他莫拉菌(22%)、肺炎链球菌(18%)是常见的微生物。结论:毛细支气管炎患儿MV平均持续时间为4天,死亡率低,SBI发生率为56%。早产、多病毒和SBI是MV持续时间延长的危险因素。
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引用次数: 0
The Go Sheet: Evaluation and Implementation of a Tool for Mass Neonatal Transport 胎动表:评估和实施大规模新生儿运输工具
Pub Date : 2023-05-25 DOI: 10.29011/2575-825x.100265
S. M. Perez, J. Andrews, Mai-anh Vuong-Dac, Shasha, Bai, Kristin Lyle, D. Matlock, Zackary Shearer, B. Jessica, Beavers
Go Sheet: Evaluation and Implementation of a Tool for
工作表:工具的评估和实施
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引用次数: 0
Platelet Functions as Gender Specific Biomarkers in Kawasaki Disease 血小板功能作为川崎病的性别特异性生物标志物
Pub Date : 2023-05-19 DOI: 10.29011/2575-825x.100263
I. T. D. Jacobis, E. Straface, Marta Mosticchio, Giovanni Orso, A. Vittucci, L. Gambardella, C. Cittadini, A. Villani, Alessandra Marchesi
) Platelet Functions as Gender Specific Biomarkers in Kawasaki Disease. Arch Pediatr
血小板功能作为川崎病的性别特异性生物标志物。拱Pediatr
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引用次数: 0
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Archives of pediatrics
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