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Evaluation of 7 urinary metabolites of polycyclic aromatic hydrocarbons during a wildfire response as part of the Wildland Firefighter Exposure and Health Effects Study. 野火反应中7种多环芳烃尿液代谢物的评估,作为野火消防员暴露和健康影响研究的一部分。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-06-30 DOI: 10.1093/annweh/wxaf024
Alexander C Mayer, Kenneth W Fent, I-Chen Chen, Kathleen Navarro DuBose, Corey R Butler, Molly West, Antonia M Calafat, Julianne Cook Botelho, Christine Toennis, Juliana Meadows, Deborah Sammons

The occupation of firefighting, including wildland firefighting, has been classified as a known human carcinogen by the International Agency for Research on Cancer. Wildland firefighters (WFFs) can be exposed to polycyclic aromatic hydrocarbons (PAHs) present in wildfire smoke, some of which are known or probable carcinogens. Currently, there is no approved respiratory protection for WFFs against wildfire smoke, making inhalation exposure to PAHs a health concern. Recent studies have also highlighted the risk of dermal exposure to PAHs for WFFs due to factors like elevated skin temperature, sweat, and the inability to shower or routinely conduct good skin hygiene practices during wildfire incidents. This pilot study aimed to assess PAH exposure among 19 WFFs in different job positions during a wildfire incident by determining urine concentrations of 7 PAH metabolites in samples collected before and after shifts across 3 days. Overall, we observed increases from pre- to post-shift for all 7 PAH metabolites when we combined all WFF samples across the 3 days. When we stratified by job position and by day, concentrations of the PAH metabolites significantly increased from pre- to post-shift for 88% (37/42) of the comparisons (P-values <0.05). Additionally, median post-shift creatinine-corrected concentrations of 2-hydroxynaphthalene exceeded the 95th percentile of the nonsmoking US general population in 67% (4/6) of comparisons. Post-shift concentrations of hydroxynaphthalenes also exceeded concentrations measured in structural firefighters responding to training fires. Overall, 2-hydroxynaphthalene was highest on Day 2 (median creatinine-corrected concentrations of 2-hydroxynaphthalene from pre- to post-shift increased 425% for crew member/overhead; 146% for saw team). Despite this finding, we did not observe significant differences by job position. However, future studies could evaluate how job position affects WFF exposures while also exploring how dermal and inhalation contribute to WFFs' PAH exposure burden.

国际癌症研究机构(International Agency for Research on Cancer)已将消防员(包括荒地消防员)列为已知的人类致癌物。野外消防员(wff)可能会暴露在野火烟雾中存在的多环芳烃(PAHs)中,其中一些是已知的或可能的致癌物质。目前,没有批准的呼吸保护措施,以防止野火烟雾,使吸入暴露于多环芳烃的健康问题。最近的研究还强调了wff皮肤接触多环芳烃的风险,这是由于皮肤温度升高、出汗、无法淋浴或在野火事件中经常进行良好的皮肤卫生习惯等因素造成的。本初步研究旨在通过测定3天轮班前后样本中7种多环芳烃代谢物的尿液浓度,评估野火事件中19名不同工作岗位的wff的多环芳烃暴露情况。总的来说,当我们在3天内结合所有WFF样本时,我们观察到所有7种多环芳烃代谢物从轮班前到轮班后都有所增加。当我们按工作岗位和白天分层时,88%(37/42)的比较(p值)的PAH代谢物浓度从轮班前到轮班后显著增加
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引用次数: 0
Association of occupational testicular radiation exposure with offspring sex ratio. 职业性睾丸辐射照射与后代性别比的关系。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-06-30 DOI: 10.1093/annweh/wxae093
Yasukazu Hijikata, Tsukasa Kamitani, Yosuke Yamamoto, Takahiro Itaya, Yoshinori Matsuoka, Koichi Morota, Haruki Funao, Masayuki Miyagi, Tadatsugu Morimoto, Haruo Kanno, Akinobu Suzuki, Yoshihisa Kotani, Ken Ishii

Objectives: The association between paternal occupational radiation exposure and the sex ratio of offspring remains controversial. Therefore, we aimed to explore testicular radiation exposure in spine surgeons and its association with their offspring's sex ratio.

Methods: The Minimally Invasive Spine Treatment Society in Japan administered a survey in October 2020. Male surgeons were divided into high- and low-radiation exposure groups according to the type of lead protectors used during the time frame surrounding the child's conception. Apron-type lead protectors were associated with high exposure, while no radiation or using a coat-type protector was considered low exposure. Risk ratios were calculated via generalized estimating equations with a log link binomial distribution. A secondary analysis was conducted wherein the high-exposure group was further divided into 2 categories based on whether they were in a posture that facilitated exposure during the procedures.

Results: A total of 209 male surgeons participated, providing responses regarding 436 children, of which 308 and 128 were associated with high and low radiation exposure, respectively. There were more female children in the high-exposure group (53% versus 39%). The adjusted risk ratio for the child being female with high exposure was 1.35 (95% CI: 1.04 to 1.73). A dose-response relationship was observed: the adjusted risk ratios for high exposure with and without an exposure-prone posture were 1.36 (1.04 to 1.78) and 1.30 (0.96 to 1.78), respectively.

Conclusions: High radiation exposure to the testes is associated with a lower male-sex ratio in offspring. Medical professionals using radiation should ensure proper radiation protection.

目的:父亲职业辐射暴露与后代性别比例之间的关系仍存在争议。因此,我们旨在探讨脊柱外科医生睾丸辐射暴露及其与后代性别比的关系。方法:日本微创脊柱治疗学会于2020年10月进行了一项调查。根据在孩子受孕期间使用的铅保护剂类型,将男性外科医生分为高辐射暴露组和低辐射暴露组。围裙型铅保护器与高暴露有关,而无辐射或使用外套型保护器被认为是低暴露。采用对数链二项分布的广义估计方程计算风险比。进行了第二次分析,根据他们在手术过程中是否处于有利于暴露的姿势,将高暴露组进一步分为两类。结果:共有209名男性外科医生参与,提供了436名儿童的反馈,其中高辐射暴露者308名,低辐射暴露者128名。高暴露组有更多的女童(53%对39%)。高暴露儿童为女性的调整风险比为1.35 (95% CI: 1.04至1.73)。观察到剂量-反应关系:有暴露倾向姿势和没有暴露倾向姿势的高暴露调整风险比分别为1.36(1.04 ~ 1.78)和1.30(0.96 ~ 1.78)。结论:睾丸高辐射暴露与后代男性性别比较低有关。使用辐射的医疗专业人员应确保适当的辐射防护。
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引用次数: 0
A quantitative solar ultraviolet radiation job-exposure matrix for Europe. 欧洲定量太阳紫外线辐射工作暴露矩阵。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-04-24 DOI: 10.1093/annweh/wxaf011
Else T Würtz, Kirsten Pugdahl, Morten Fenger-Grøn, Ina A Berglind, Mark P C Cherrie, Anna Dahlman-Höglund, Kasper Grandahl, Jelena Macan, Alberto Modenese, Hilde Notø, Svetlana Solovieva, Kurt Straif, Marc Wittlich, Sven Connemann, Timo Heepenstrick, Peter A Philipsen, Stephan Westerhausen, Calvin B Ge, Johnni Hansen, Cheryl E Peters, Ingrid Sivesind Mehlum, Vivi Schlünssen, Henrik A Kolstad

Introduction: Outdoor workers are exposed to high levels of solar ultraviolet radiation (UVR). UVR causes skin cancer and is a risk factor for cataract and other short- and long-term health effects, but there are significant knowledge gaps regarding the exposure-response relations based on quantitative measures of UVR exposure. We developed a quantitative UVR job-exposure matrix (JEM) for the general working population of Europe.

Methods: Three experts from each of Northern, Central, and Southern Europe rated duration of outdoor work for all 372 occupations defined by the International Standard Classification of Occupations from 1988 (ISCO-88(COM)). A systematic literature search identified 12 studies providing 223 sets of summary workday UVR exposure for 49 ISCO-88(COM) occupations based on 75,711 personal workday measurements obtained from 2,645 participants and reported as arithmetic mean standard erythemal dose (SED). We combined the expert ratings with the measured occupational UVR exposure data and estimated harmonized workday UVR exposures for all 372 occupations in a linear mixed effects model.

Results: Monotonically increasing workday UVR exposure of 0.68, 1.57, 1.80, and 2.49 SED were seen by increasing expert ratings of 0, 1 to 2, 3 to 4, and ≥5 h of daily outdoor work. The UVR exposure showed a 6-fold increase from lowest to highest exposed occupation. Farm hands, roofers, concrete placers, and other occupations within craft and related trades were among the highest exposed, while bartenders, wood-processing-plant operators, and several white-collar occupations who typically work indoor were among the lowest exposed.

Conclusion: This quantitative JEM for solar UVR exposure proves able to provide substantial discrimination between occupations, shows good agreement with expert assessments, and may facilitate epidemiological studies characterizing the exposure-response relation between occupational solar UVR exposure and different health effects.

户外工作人员暴露在高水平的太阳紫外线辐射(UVR)下。紫外线照射导致皮肤癌,是白内障和其他短期和长期健康影响的危险因素,但在基于紫外线照射定量测量的暴露-反应关系方面存在重大知识空白。我们为欧洲的一般工作人口开发了一个定量的紫外线辐射工作暴露矩阵(JEM)。方法:来自北欧、中欧和南欧的三位专家分别对1988年国际职业标准分类(ISCO-88(COM))定义的所有372种职业的户外工作时间进行了评估。系统的文献检索确定了12项研究,提供了49种ISCO-88(COM)职业的223组工作日紫外线暴露总结,这些研究基于从2645名参与者中获得的75711个个人工作日测量数据,并报告为算术平均标准红斑剂量(SED)。我们将专家评级与测量的职业UVR暴露数据结合起来,并在线性混合效应模型中估计所有372个职业的协调工作日UVR暴露。结果:通过增加每天户外工作0、1至2、3至4和≥5小时的专家评分,可以单调地增加工作日UVR暴露0.68、1.57、1.80和2.49 SED。紫外线暴露从最低到最高暴露的职业增加了6倍。农场工人、屋顶工人、混凝土浇筑工和其他工艺及相关行业的职业受污染程度最高,而调酒师、木材加工厂操作员和一些通常在室内工作的白领职业受污染程度最低。结论:太阳紫外线照射的定量JEM能够在职业之间提供实质性的区分,与专家评估结果吻合良好,并可为描述职业太阳紫外线照射与不同健康影响之间的暴露-反应关系的流行病学研究提供便利。
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引用次数: 0
High levels of heat stress among sugarcane workers in Thailand. 泰国甘蔗工人热应激反应严重。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-04-24 DOI: 10.1093/annweh/wxaf002
Tadpong Tantipanjaporn, Andrew Povey, Holly A Shiels, Martie van Tongeren

Objectives: With continued global warming, the effects of elevated temperatures on the health of agricultural workers are a particular concern. This study characterized the levels of heat stress in Thai sugarcane workers and investigated whether season and harvesting method were associated with it.

Methods: Three hundred sugarcane workers in Nakhon Sawan Province, Thailand, were recruited, and information on demographics, working conditions, and clothing characteristics was collected from participants during the cooler months (n = 152 participants, mid-January to mid-February) and hotter month (n = 148, March). Heat stress was measured using the Wet Bulb Globe Temperature (WBGT) index, and the WBGT instruments were operated for a full work shift in the sugarcane fields where the participants worked. One-hour time weighted average (TWA) effective WBGT (WBGTeff-1hrTWA) estimates were determined for different times of the day based on the measured WBGT and clothing adjustment factor.

Results: The average WBGTeff-1hrTWA in the cooler months ranged from 22.5 °C during the early morning to 31.3 °C during the hottest time of the day, and for the hotter month, it ranged from 25.4 °C to 33.9 °C, respectively. The measured WBGT, natural wet-bulb temperature (Tnwb), dry-bulb temperature (Tdb), globe temperature (Tg), air velocity (Av), and absolute water vapor pressure (ea) were all statistically significantly higher in the hotter month than in the cooler months. Harvesting during the hotter month and harvesting burnt sugarcane were significantly associated with increased effective WBGT. The harvesters' heat stress in both seasons exceeded the American Conference of Governmental Industrial Hygienists - Threshold limit value for 72.7% of the working time in the cooler months and 90.9% in the hotter month.

Conclusions: The heat stress in Thai sugarcane workers was high in both seasons, particularly in the hotter month and when harvesting burnt sugarcane. This results in a very high risk of developing heat-related health effects, and measures are needed to reduce heat stress. Heat stress in agricultural and other outdoor work in tropical climates is an immediate and growing problem.

目标:随着全球持续变暖,气温升高对农业工人健康的影响是一个特别令人关切的问题。本研究描述了泰国甘蔗工人的热应激水平,并调查了季节和收获方法是否与之相关。方法:在泰国那空沙万省招募了300名甘蔗工人,在较冷的月份(n = 152名,1月中旬至2月中旬)和较热的月份(n = 148名,3月)收集了参与者的人口统计、工作条件和服装特征信息。热应力是用湿球温度(WBGT)指数来测量的,WBGT仪器在参与者工作的甘蔗田进行了一个完整的工作轮班。一小时时间加权平均(TWA)有效WBGT (WBGTeff-1hrTWA)估计是基于测量的WBGT和服装调整因子在一天中的不同时间确定的。结果:较冷月份的平均WBGTeff-1hrTWA范围为清晨22.5°C至最热时段31.3°C,较热月份的平均WBGTeff-1hrTWA范围为25.4°C至33.9°C。实测WBGT、自然湿球温度(Tnwb)、干球温度(Tdb)、全球温度(Tg)、空气速度(Av)和绝对水汽压(ea)在较热月份均显著高于较冷月份。在较热的月份收获和收获烧焦的甘蔗与有效WBGT的增加显著相关。收获机在两个季节的热应激均超过了美国政府工业卫生学家会议的阈值,在较冷的月份有72.7%的工作时间超过了美国政府工业卫生学家会议的阈值,在较热的月份有90.9%的工作时间超过了美国政府工业卫生学家会议的阈值。结论:泰国甘蔗工人的热应激在两个季节都很高,特别是在较热的月份和收获烧焦甘蔗时。这导致与热有关的健康影响的风险非常高,需要采取措施减少热应激。在热带气候下,农业和其他户外工作中的热应激是一个迫在眉睫且日益严重的问题。
{"title":"High levels of heat stress among sugarcane workers in Thailand.","authors":"Tadpong Tantipanjaporn, Andrew Povey, Holly A Shiels, Martie van Tongeren","doi":"10.1093/annweh/wxaf002","DOIUrl":"10.1093/annweh/wxaf002","url":null,"abstract":"<p><strong>Objectives: </strong>With continued global warming, the effects of elevated temperatures on the health of agricultural workers are a particular concern. This study characterized the levels of heat stress in Thai sugarcane workers and investigated whether season and harvesting method were associated with it.</p><p><strong>Methods: </strong>Three hundred sugarcane workers in Nakhon Sawan Province, Thailand, were recruited, and information on demographics, working conditions, and clothing characteristics was collected from participants during the cooler months (n = 152 participants, mid-January to mid-February) and hotter month (n = 148, March). Heat stress was measured using the Wet Bulb Globe Temperature (WBGT) index, and the WBGT instruments were operated for a full work shift in the sugarcane fields where the participants worked. One-hour time weighted average (TWA) effective WBGT (WBGTeff-1hrTWA) estimates were determined for different times of the day based on the measured WBGT and clothing adjustment factor.</p><p><strong>Results: </strong>The average WBGTeff-1hrTWA in the cooler months ranged from 22.5 °C during the early morning to 31.3 °C during the hottest time of the day, and for the hotter month, it ranged from 25.4 °C to 33.9 °C, respectively. The measured WBGT, natural wet-bulb temperature (Tnwb), dry-bulb temperature (Tdb), globe temperature (Tg), air velocity (Av), and absolute water vapor pressure (ea) were all statistically significantly higher in the hotter month than in the cooler months. Harvesting during the hotter month and harvesting burnt sugarcane were significantly associated with increased effective WBGT. The harvesters' heat stress in both seasons exceeded the American Conference of Governmental Industrial Hygienists - Threshold limit value for 72.7% of the working time in the cooler months and 90.9% in the hotter month.</p><p><strong>Conclusions: </strong>The heat stress in Thai sugarcane workers was high in both seasons, particularly in the hotter month and when harvesting burnt sugarcane. This results in a very high risk of developing heat-related health effects, and measures are needed to reduce heat stress. Heat stress in agricultural and other outdoor work in tropical climates is an immediate and growing problem.</p>","PeriodicalId":8362,"journal":{"name":"Annals Of Work Exposures and Health","volume":" ","pages":"401-414"},"PeriodicalIF":1.8,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cleaning as high-risk activity for respiratory particulate exposure during additive manufacturing of sand moulds and its preceding silica sand coating process. 在砂模增材制造及其之前的硅砂涂层过程中,清洗是呼吸道微粒暴露的高风险活动。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-04-24 DOI: 10.1093/annweh/wxaf010
Ntoko Lucas Matlhatsi, Sonette du Preez, Cornelius J Van Der Merwe, Stephanus J L Linde

Background: Occupational exposure to respirable crystalline silica (RCS) is a known cause of respiratory diseases, such as silicosis and lung cancer. Binder jetting additive manufacturing (AM) uses silica sand coated with sulphonic acid as feedstock material and operators are potentially exposed to RCS during various activities associated with AM. This includes the cleaning of the AM machine and associated equipment. This study aimed to investigate particulate exposures associated with additive manufacturing of sand moulds and its preceding silica sand coating process.

Methods: The particle size distribution (PSD) and particle shape analysis of different forms of silica sand (virgin, coated, and used) was determined using a Malvern Morphologi G3 automated microscope and the structural characteristics was measured using X-ray diffraction (XRD). Personal exposure and area monitoring for airborne respirable dust and RCS were performed using MDHS 14/4 and NIOSH 7602, while real-time particle number concentrations of 0.3 to 10 µm sized particles was measured using the TSI Aerosol Particle Counter (APC). Monitoring was performed for 2 operators over 8 d and included 3 d of coating, one day of cleaning the AM machine, and 4 d of printing during which 3 identical parts were manufactured.

Results: According to the PSD analysis, virgin and used silica sand particles were mostly in the respirable size range (d(0.9) = 3.98 ± 0.72 µm; and d(0.9) = 6.51 ± 2.71 µm, respectively), while coated sand was mostly in the inhalable size fraction d(0.5) = 29.76 ± 42.91 µm). The wt% results of the XRD analysis for the bulk virgin, coated and used silica sand were 97.3%, 92.6%, and 96.8% quartz, respectively. Personal exposure to RCS exceeded the exposure limit of 0.1 mg/m3 when the operator used compressed air to clean the coating machine's filter (0.112 mg/m3) and exceeded the action level on the day the AM machine was cleaned (0.70 mg/m3). The results for real-time particle number concentrations of 0.3 to 10 µm sized particles showed peaks while the cleaning activities such as dry sweeping were performed.

Conclusion: The personal exposure to RCS was the highest on days when cleaning activities that used compressed air and dry sweeping took place. The high quartz content of the silica sand feedstock material and the respirable size of the virgin and used silica sand particles means that cleaning activities pose an RCS exposure risk to AM operators. Nine recommendations are made to reduce exposure to RCS during cleaning activities.

背景:职业性暴露于可呼吸性结晶二氧化硅(RCS)是导致呼吸系统疾病的已知原因,如矽肺病和肺癌。粘结剂喷射增材制造(AM)使用涂有磺酸的硅砂作为原料,操作人员在与AM相关的各种活动中可能会接触到RCS。这包括AM机器和相关设备的清洁。本研究旨在研究与砂模增材制造及其之前的硅砂涂层工艺相关的颗粒暴露。方法:采用Malvern Morphologi G3自动显微镜对不同形态的硅砂(未加工、包覆和使用)进行粒度分布(PSD)和颗粒形状分析,并用x射线衍射(XRD)测量其结构特征。使用MDHS 14/4和NIOSH 7602对空气中可吸入性粉尘和RCS进行个人暴露和区域监测,同时使用TSI气溶胶粒子计数器(APC)实时测量0.3至10µm大小的颗粒数浓度。对2名操作员进行了8天的监测,包括3天的涂层,1天的AM机器清洁,4天的打印,在此期间制造了3个相同的零件。结果:根据PSD分析,原始和使用过的硅砂颗粒大多在可呼吸的尺寸范围内(d(0.9) = 3.98±0.72µm;d(0.9) = 6.51±2.71µm),包覆砂主要处于可吸入粒径段d(0.5) = 29.76±42.91µm。XRD分析结果表明,散装原生硅砂、包覆硅砂和废硅砂的石英含量分别为97.3%、92.6%和96.8%。当操作人员使用压缩空气清洁涂布机过滤器时,个人接触RCS超过0.1 mg/m3的暴露限值(0.112 mg/m3),超过AM机清洁当天的行动水平(0.70 mg/m3)。当进行干扫等清洁活动时,0.3 ~ 10µm粒径颗粒的实时颗粒数浓度出现峰值。结论:在使用压缩空气和干式扫地进行清洁活动时,RCS的个人暴露量最高。硅砂原料的高石英含量以及原始和使用过的硅砂颗粒的可吸入尺寸意味着清洗活动对AM操作员构成RCS暴露风险。提出了九项建议,以减少在清洁活动期间接触RCS。
{"title":"Cleaning as high-risk activity for respiratory particulate exposure during additive manufacturing of sand moulds and its preceding silica sand coating process.","authors":"Ntoko Lucas Matlhatsi, Sonette du Preez, Cornelius J Van Der Merwe, Stephanus J L Linde","doi":"10.1093/annweh/wxaf010","DOIUrl":"10.1093/annweh/wxaf010","url":null,"abstract":"<p><strong>Background: </strong>Occupational exposure to respirable crystalline silica (RCS) is a known cause of respiratory diseases, such as silicosis and lung cancer. Binder jetting additive manufacturing (AM) uses silica sand coated with sulphonic acid as feedstock material and operators are potentially exposed to RCS during various activities associated with AM. This includes the cleaning of the AM machine and associated equipment. This study aimed to investigate particulate exposures associated with additive manufacturing of sand moulds and its preceding silica sand coating process.</p><p><strong>Methods: </strong>The particle size distribution (PSD) and particle shape analysis of different forms of silica sand (virgin, coated, and used) was determined using a Malvern Morphologi G3 automated microscope and the structural characteristics was measured using X-ray diffraction (XRD). Personal exposure and area monitoring for airborne respirable dust and RCS were performed using MDHS 14/4 and NIOSH 7602, while real-time particle number concentrations of 0.3 to 10 µm sized particles was measured using the TSI Aerosol Particle Counter (APC). Monitoring was performed for 2 operators over 8 d and included 3 d of coating, one day of cleaning the AM machine, and 4 d of printing during which 3 identical parts were manufactured.</p><p><strong>Results: </strong>According to the PSD analysis, virgin and used silica sand particles were mostly in the respirable size range (d(0.9) = 3.98 ± 0.72 µm; and d(0.9) = 6.51 ± 2.71 µm, respectively), while coated sand was mostly in the inhalable size fraction d(0.5) = 29.76 ± 42.91 µm). The wt% results of the XRD analysis for the bulk virgin, coated and used silica sand were 97.3%, 92.6%, and 96.8% quartz, respectively. Personal exposure to RCS exceeded the exposure limit of 0.1 mg/m3 when the operator used compressed air to clean the coating machine's filter (0.112 mg/m3) and exceeded the action level on the day the AM machine was cleaned (0.70 mg/m3). The results for real-time particle number concentrations of 0.3 to 10 µm sized particles showed peaks while the cleaning activities such as dry sweeping were performed.</p><p><strong>Conclusion: </strong>The personal exposure to RCS was the highest on days when cleaning activities that used compressed air and dry sweeping took place. The high quartz content of the silica sand feedstock material and the respirable size of the virgin and used silica sand particles means that cleaning activities pose an RCS exposure risk to AM operators. Nine recommendations are made to reduce exposure to RCS during cleaning activities.</p>","PeriodicalId":8362,"journal":{"name":"Annals Of Work Exposures and Health","volume":" ","pages":"429-441"},"PeriodicalIF":1.8,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Airborne particulate matter exposure in male sugarcane workers at risk for chronic kidney disease in Guatemala. 危地马拉男性甘蔗工人暴露在空气中的颗粒物有患慢性肾病的危险。
IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-04-24 DOI: 10.1093/annweh/wxaf008
John L Adgate, Grant Erlandson, Jaime Butler-Dawson, Laura Calvimontes-Barrientos, Luis Amezquita, James Seidel, Joaquin Barnoya, Colton Castro, Magali Coyoy, Marcos Pérez, Miranda Dally, Lyndsay Krisher, Diana Jaramillo, Stephen Brindley, Lee S Newman, Joshua Schaeffer

Background: There is an international epidemic of chronic kidney disease of unknown cause (CKDu) in agricultural working populations. Particulate air pollution is a likely contributing factor in populations at risk for CKDu, but there is little personal breathing zone data for these workers.

Methods: We collected 1 to 3 personal breathing zone particulate matter <5 microns (PM5) gravimetric measurements in 143 male sugarcane harvesters over 2 seasons and concurrent ambient samples using personal sampling pumps and cyclone inlets as a sampling train. Due to very high concentrations observed during a pilot of these methods, personal breathing zone sampling duration was set to 4 h, beginning either at the start of a work shift (AM) or delayed for 4 h (PM). To obtain full-shift exposure concentrations we calculated 8-h time-weighted average (TWA, in µg/m3) estimates of each worker's full-shift personal breathing zone PM5 exposure concentration by averaging their individual monitored concentration with the median concentration of the unmonitored AM or PM segment from all workers that day to obtain an 8-h TWA.

Results: Median full-shift personal TWA PM5 concentrations were 449 μg/m3 (range 20.5 to 1,930 μg/m3), which were much higher than ambient concentrations in these fields (median 136, range 22.5 to 2,360 μg/m3). These findings document very high personal breathing zone PM5 exposure in workers at risk for CKDu: median concentrations for all workers were 3.5 (range <1 to 33.6) times as high as concurrent ambient concentrations.

Significance: These findings suggest that ambient measurements of particulate matter are insufficient to estimate personal exposure in this population and that personal breathing zone monitoring should be used to fully explore air pollution as a risk factor for CKDu. Given that particulate matter from this source likely has multiple hazardous constituents, future research should focus on characterizing all constituents and explore associations with biomarkers of kidney injury.

背景:不明原因慢性肾脏疾病(CKDu)在农业工作人群中呈国际流行趋势。空气微粒污染可能是CKDu高危人群的一个因素,但这些工人的个人呼吸区数据很少。结果:全班个人TWA PM5浓度中位数为449 μg/m3(范围为20.5 ~ 1930 μg/m3),远高于该区域环境浓度(中位数为136,范围为22.5 ~ 2360 μg/m3)。这些发现证明CKDu风险工人的个人呼吸区PM5暴露非常高:所有工人的中位数浓度为3.5(范围)。意义:这些发现表明,环境颗粒物测量不足以估计该人群的个人暴露,个人呼吸区监测应用于充分探索空气污染作为CKDu的危险因素。鉴于来自该来源的颗粒物可能含有多种有害成分,未来的研究应侧重于表征所有成分并探索与肾损伤生物标志物的关联。
{"title":"Airborne particulate matter exposure in male sugarcane workers at risk for chronic kidney disease in Guatemala.","authors":"John L Adgate, Grant Erlandson, Jaime Butler-Dawson, Laura Calvimontes-Barrientos, Luis Amezquita, James Seidel, Joaquin Barnoya, Colton Castro, Magali Coyoy, Marcos Pérez, Miranda Dally, Lyndsay Krisher, Diana Jaramillo, Stephen Brindley, Lee S Newman, Joshua Schaeffer","doi":"10.1093/annweh/wxaf008","DOIUrl":"10.1093/annweh/wxaf008","url":null,"abstract":"<p><strong>Background: </strong>There is an international epidemic of chronic kidney disease of unknown cause (CKDu) in agricultural working populations. Particulate air pollution is a likely contributing factor in populations at risk for CKDu, but there is little personal breathing zone data for these workers.</p><p><strong>Methods: </strong>We collected 1 to 3 personal breathing zone particulate matter <5 microns (PM5) gravimetric measurements in 143 male sugarcane harvesters over 2 seasons and concurrent ambient samples using personal sampling pumps and cyclone inlets as a sampling train. Due to very high concentrations observed during a pilot of these methods, personal breathing zone sampling duration was set to 4 h, beginning either at the start of a work shift (AM) or delayed for 4 h (PM). To obtain full-shift exposure concentrations we calculated 8-h time-weighted average (TWA, in µg/m3) estimates of each worker's full-shift personal breathing zone PM5 exposure concentration by averaging their individual monitored concentration with the median concentration of the unmonitored AM or PM segment from all workers that day to obtain an 8-h TWA.</p><p><strong>Results: </strong>Median full-shift personal TWA PM5 concentrations were 449 μg/m3 (range 20.5 to 1,930 μg/m3), which were much higher than ambient concentrations in these fields (median 136, range 22.5 to 2,360 μg/m3). These findings document very high personal breathing zone PM5 exposure in workers at risk for CKDu: median concentrations for all workers were 3.5 (range <1 to 33.6) times as high as concurrent ambient concentrations.</p><p><strong>Significance: </strong>These findings suggest that ambient measurements of particulate matter are insufficient to estimate personal exposure in this population and that personal breathing zone monitoring should be used to fully explore air pollution as a risk factor for CKDu. Given that particulate matter from this source likely has multiple hazardous constituents, future research should focus on characterizing all constituents and explore associations with biomarkers of kidney injury.</p>","PeriodicalId":8362,"journal":{"name":"Annals Of Work Exposures and Health","volume":" ","pages":"377-388"},"PeriodicalIF":2.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychosocial risks and ethical implications of technology: considerations for decent work. 技术的社会心理风险和伦理影响:对体面工作的考虑。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-04-24 DOI: 10.1093/annweh/wxaf003
Paul A Schulte, Jessica M K Streit

Decent work, a United Nations Sustainable Development Goal, is built on the ethical treatment of workers and ensures respect of their security, freedom, equity, and dignity. In the future, a wide range of technological forces may pose significant impediments to the availability and quality of decent work. This paper applies a prescriptive taxonomy to categorize evidence of the psychosocial impacts technology may bring to the future of work and elucidate the associated ethical concerns. Ethical objectives in support of a future defined by decent work are also offered. Central to this technoethical discourse are the principles of nonmaleficence, beneficence, autonomy, justice, and respect for persons. Expanded technoethical education, ethical technology assessments, ethical foresight analysis, and revised ethical standards are important ways to address technology-related ethical challenges on a larger scale. The findings in this paper may serve as a foundation for the systemic prevention and control of adverse effects and ethical concerns from the use of technology in the workplace of the future.

体面劳动是联合国可持续发展目标之一,它建立在对工人的道德待遇之上,确保尊重他们的安全、自由、公平和尊严。未来,各种各样的技术力量可能对体面工作的提供和质量构成重大障碍。本文采用一种规定性分类法对技术可能给未来工作带来的社会心理影响的证据进行分类,并阐明相关的伦理问题。还提出了支持以体面工作为定义的未来的道德目标。这种技术伦理话语的核心是无害、仁慈、自主、正义和尊重人的原则。扩大技术伦理教育、伦理技术评估、伦理前瞻分析和修订伦理标准是在更大范围内解决与技术相关的伦理挑战的重要途径。本文的研究结果可以作为系统预防和控制未来工作场所使用技术的不利影响和伦理问题的基础。
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引用次数: 0
Personal air monitoring and biological assessment of perchloroethylene exposure in workers in the dry-cleaning industry in Bogotá, Colombia. 哥伦比亚波哥大<e:1>干洗业工人接触过氯乙烯的个人空气监测和生物学评估。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-04-24 DOI: 10.1093/annweh/wxaf009
Maira Fernanda Zambrano Carrillo, Karen López Castro, Stefano Basilico

This study examines occupational exposure to perchloroethylene among dry cleaning workers in Bogotá, Colombia, where its use remains prevalent despite global trends toward alternatives. A cross-sectional analysis was conducted with 9 workers to measure perchloroethylene exposure levels and blood concentrations. Additionally, a case-control study assessed gamma glutamyl transferase (GGT) and alanine aminotransferase (ALT) as biomarkers for hepatocellular damage. Workers were classified into 3 job categories: dry cleaning operators, ironers, and cold washing operators. Results indicated that dry cleaning operators experienced significantly higher exposure levels (0.72 to 7.22 ppm) compared to ironers and cold washers (0.001 to 3.39 ppm). All exposure levels were below the adjusted threshold limit of 19.58 ppm, and blood perchloroethylene concentrations were below detection limits. No significant differences in GGT and ALT levels were observed between exposed workers and the control group. Given the small sample size, further research is warranted to better understand exposure risks in this sector. Emphasizing a culture of prevention is crucial due to the carcinogenic potential of perchloroethylene, even at low environmental exposure levels.

本研究调查了哥伦比亚波哥大干洗工人的职业接触过氯乙烯,尽管全球趋势趋向于替代品,但它的使用仍然普遍。对9名工人进行了横断面分析,以测量全氯乙烯暴露水平和血液浓度。此外,一项病例对照研究评估了γ -谷氨酰转移酶(GGT)和丙氨酸转氨酶(ALT)作为肝细胞损伤的生物标志物。工人被分为三个工作类别:干洗操作员、熨烫工和冷洗操作员。结果表明,与熨烫工和冷洗工(0.001至3.39 ppm)相比,干洗工的暴露水平(0.72至7.22 ppm)明显更高。所有暴露水平均低于19.58 ppm的调整阈值限值,血液中过氯乙烯浓度低于检测限值。暴露工人与对照组之间GGT和ALT水平无显著差异。鉴于样本量较小,有必要进一步研究以更好地了解该行业的暴露风险。由于全氯乙烯即使在低环境暴露水平下也具有致癌潜力,因此强调预防文化至关重要。
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引用次数: 0
Daily noise dose and power tool characterization of steel stud framers on commercial construction sites. 商业建筑工地钢柱框架的日噪声剂量和电动工具特性。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-04-24 DOI: 10.1093/annweh/wxaf005
David Schutt, Tiffany Lipsey, Mike Van Dyke, William J Brazile

The construction industry is well-documented as having numerous sources of hazardous noise on the job. Framers who cut and install steel studs on commercial construction sites use a variety of power tools throughout the course of their normal workday and have the potential to be exposed to levels of noise that can lead to occupational noise-induced hearing loss. This study assessed the noise dose of commercial steel stud framers and characterized the noise of common power tools that contribute to their daily noise dose. Occupational exposure limits exist in both required and recommended forms to protect workers; however, large differences in the level of worker protection are apparent between the mandated Occupational Safety and Health Administration (OSHA) permissible exposure limit (PEL) and the voluntary National Institute for Occupational Safety and Health (NIOSH) recommended exposure limit (REL) for noise exposure. Steel stud framers in this study had a mean OSHA PEL dose of 27.6% and a mean NIOSH REL dose of 340.7% for the same workers. As a comparison, ambient equivalent noise doses at the construction site were 1.4% for PEL criteria and 12.4% for REL criteria. Of task assignments during the workday, workers who were assigned primarily as saw operators had statistically significant higher noise exposures than workers who were assigned as stud installers (P = 0.037). Octave band analysis was conducted for full-day exposures and indicated an upward trend of higher noise exposures at higher frequencies. Overall, among all steel stud framers involved in this study, all workers had noise doses below the OSHA PEL (range 5.8% to 61.4%), and all but 2 workers (n = 35) had noise doses above the NIOSH REL (range 63.9% to 823.2%), indicating exposure to hazardous levels of noise based on more protective RELs.

建筑行业有充分的证据表明,在工作中有许多有害的噪音来源。在商业建筑工地切割和安装钢钉的制铁工人在正常的工作日中使用各种电动工具,并且有可能暴露在可能导致职业性噪音引起的听力损失的噪音中。本研究评估了商业钢钉框架的噪音剂量,并描述了普通电动工具的噪音对他们的日常噪音剂量的影响。为保护工人,规定和建议的职业接触限值都存在;然而,在强制规定的职业安全与健康管理局(OSHA)允许暴露限值(PEL)和自愿规定的国家职业安全与健康研究所(NIOSH)建议的噪声暴露限值(REL)之间,工人保护水平明显存在很大差异。在这项研究中,钢铁钉架工人的OSHA PEL平均剂量为27.6%,NIOSH REL平均剂量为340.7%。作为比较,建筑工地的环境等效噪声剂量按PEL标准为1.4%,按REL标准为12.4%。在工作日的任务分配中,主要被分配为锯操作人员的工人比被分配为螺柱安装人员的工人有统计学意义上的更高的噪音暴露(P = 0.037)。对全天暴露进行了八度频带分析,结果表明,高频率的高噪声暴露呈上升趋势。总体而言,在本研究涉及的所有钢螺柱框架工人中,所有工人的噪音剂量都低于OSHA PEL(范围5.8%至61.4%),除了2名工人(n = 35)外,所有工人的噪音剂量都高于NIOSH REL(范围63.9%至823.2%),表明暴露于基于更多保护性REL的危险噪音水平。
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引用次数: 0
Demographic differences in facial anthropometric data from 3D scans and implications for respirator fit. 来自3D扫描的面部人体测量数据的人口统计学差异及其对呼吸器适配的影响。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-04-24 DOI: 10.1093/annweh/wxaf012
Kayna Hobbs-Murphy, William J Brazile, Kristen Morris, John Rosecrance

Objective: In response to limitations in foundational anthropometric research efforts as well as the increasingly diversifying workforce, researchers have attempted to define the presence or absence of differences in respirator-related facial measurements between different demographic groups. The purpose of the present study was to assess the presence of differences in facial measurements from 3D scans related to respirator fit, based on demographic factors of gender, race/ethnicity, and age in a sample of 2,022 3D scans.

Methods: Three-dimensional (3D) body scanning technology was used to gather facial measurement data. Principal components analysis (PCA) and multivariate analysis of variance (MANOVA) were employed to determine the presence or absence of differences in measurements from 3D scans between the demographic groups.

Results: Results indicated that measurements from 3D scans related to respirator fit were significantly different for all groups within each demographic category (gender, race/ethnicity, and age).

Conclusion: The findings suggest that demographic factors such as gender, race/ethnicity, and age have a significant impact on facial measurements from 3D scans, which has implications for respirator fit and design considerations.

目的:为了应对基础人体测量学研究工作的局限性以及日益多样化的劳动力,研究人员试图定义不同人口群体之间与呼吸器相关的面部测量是否存在差异。本研究的目的是基于性别、种族/民族和年龄等人口统计学因素,在2022个3D扫描样本中评估与呼吸器适配相关的3D扫描面部测量结果的差异。方法:采用三维身体扫描技术采集面部测量数据。采用主成分分析(PCA)和多变量方差分析(MANOVA)来确定人口统计学组间三维扫描测量值是否存在差异。结果:结果表明,在每个人口统计类别(性别、种族/民族和年龄)中,与呼吸器适配相关的3D扫描测量值在所有组中都有显著差异。结论:研究结果表明,性别、种族/民族和年龄等人口统计学因素对3D扫描的面部测量结果有重大影响,这对呼吸器的适配和设计考虑具有重要意义。
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引用次数: 0
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Annals Of Work Exposures and Health
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