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Intersections of racism, disability, and postpartum depression in minoritized racial and ethnic populations 种族主义、残疾和产后抑郁症在少数种族和族裔人群中的交叉。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-06-13 DOI: 10.1007/s00737-025-01599-6
Maria McDonald, Genevieve Lyons, Rosemary B. Hughes, Kathryn Laughon, Casey Johnson, Jeanne L. Alhusen

Purpose

Using an intersectional lens, this study examined the association between maternal reports of emotional distress due to racism (EDR) and postpartum depression (PPD) symptoms among persons with and without disabilities in minoritized racial and ethnic populations.

Methods

An analysis of Phase 8 (2018–2020) data from the Pregnancy Risk Assessment Monitoring System (PRAMS) included 2,452 respondents with a recent live birth from three states (MO, GA, VA). We examined the association between EDR and PPD symptoms among respondents with and without disabilities using Pearson’s chi-square test. Multivariate regression models were used to further estimate the odds of PPD symptoms associated with EDR and to examine differences in this relationship by disability status.

Results

EDR was significantly associated with PPD symptoms, with a higher prevalence of PPD symptoms among those with at least one disability (52.3%) compared to those without disabilities (19.9%). After adjusting for maternal demographics, EDR was significantly associated with PPD symptoms across disability groups. No significant interaction between disability group and EDR was observed, suggesting the association’s strength did not differ significantly by disability group in this study. In the fully adjusted model, history of depression attenuated the EDR-PPD association across disability groups, highlighting the effect of prior depressive episodes on PPD outcomes.

Conclusion

EDR is significantly associated with PPD symptoms, and persons with disabilities in minoritized racial and ethnic populations may be particularly susceptible to EDR and PPD. Additional research using an intersectional perspective is needed to elucidate PPD disparities as related to multiple, intersecting social identities and experiences of discrimination.

目的:使用交叉透镜,本研究检查了少数民族种族和民族人群中有残疾和无残疾的产妇因种族主义引起的情绪困扰(EDR)与产后抑郁症(PPD)症状之间的关系。方法:对妊娠风险评估监测系统(PRAMS)的第8期(2018-2020)数据进行分析,包括来自三个州(MO, GA, VA)的2,452名近期活产的受访者。我们使用皮尔逊卡方检验检验了有和没有残疾的受访者中EDR和PPD症状之间的关系。使用多变量回归模型进一步估计PPD症状与EDR相关的几率,并检查残疾状况在这种关系中的差异。结果:EDR与PPD症状显著相关,至少有一种残疾的患者PPD症状的患病率(52.3%)高于无残疾的患者(19.9%)。在调整了产妇人口统计数据后,EDR与残疾群体的PPD症状显著相关。残障组与EDR之间无显著交互作用,提示本研究中残障组与EDR的关联强度无显著差异。在完全调整的模型中,抑郁史减弱了残疾群体中EDR-PPD的关联,强调了既往抑郁发作对PPD结局的影响。结论:EDR与PPD症状有显著相关性,少数民族人群的残疾人可能特别容易发生EDR和PPD。需要使用交叉视角的进一步研究来阐明PPD差异与多重交叉的社会身份和歧视经历有关。
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引用次数: 0
Burnout and related factors in mothers of preschool children 学龄前儿童母亲的职业倦怠及其相关因素。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-05-31 DOI: 10.1007/s00737-025-01596-9
Feyza Yılmaz, Pelin Göksel

Purpose

Being a parent, in addition to its rewarding aspects, also involves significant psychological and physical challenges. When the balance between caregiving burden and support resources is disrupted, it becomes almost inevitable for mothers to experience burnout. We designed our study to investigate the factors related to burnout complaints in mothers of preschool children.

Methods

The sample of our study consisted of 80 mothers who presented to psychiatry clinics with burnout complaints and 80 healthy controls. Data collection tools included the Maslach Burnout Inventory, the Parenting Stress Index, and the Spousal Support Scale. Scale scores were compared between the groups. The mediating role of the Spousal Support Scale (SSS) in the relationship between the Parenting Stress Index (PSI) and the Maslach Burnout Inventory (MBI) was tested using path analysis.

Results

No statistically significant age difference was found between the two groups (p > 0.05). The number of children among participants in the burnout group was higher (p = 0.018).In the burnout group, a positive and statistically significant relationship was found between the total scores of the Maslach Burnout Inventory (MBI) and the Parenting Stress Index (PSI) (r: 0.664; p: 0.000), and a negative and statistically significant relationship with the total score of the Spousal Support Scale (SSS) (r: -0.409; p: 0.000).The indirect effect of the Parenting Stress Index (PSI) on the Maslach Burnout Inventory (MBI) through the Spousal Support Scale (SSS) was found to be statistically significant ( (:beta:) = -0.3294, p < 0.001).

Conclusion

Parental stress is associated with the level of burnout in mothers. However, spousal support may weaken the relationship between parental stress and burnout. Further research on the relationship between spousal support and burnout, as well as awareness projects related to spousal support, is needed.

目的:为人父母,除了它的回报方面,也涉及重大的心理和生理挑战。当照顾负担和支持资源之间的平衡被打破时,母亲们几乎不可避免地会感到倦怠。本研究旨在探讨学龄前儿童母亲倦怠投诉的相关因素。方法:本研究的样本包括80名到精神病学诊所就诊的母亲和80名健康对照者。数据收集工具包括马斯拉克倦怠量表、养育压力指数和配偶支持量表。比较两组间的量表得分。采用通径分析方法检验配偶支持量表(SSS)在养育压力指数(PSI)和马斯拉奇倦怠量表(MBI)之间的中介作用。结果:两组患者年龄差异无统计学意义(p < 0.05)。倦怠组被试中儿童人数较高(p = 0.018)。在倦怠组,Maslach倦怠量表(MBI)总分与父母压力指数(PSI)呈显著正相关(r: 0.664;p: 0.000),与配偶支持量表(SSS)总分呈负相关且有统计学意义(r: -0.409;p: 0.000)。通过配偶支持量表(SSS),发现父母压力指数(PSI)对Maslach倦怠量表(MBI)的间接影响具有统计学意义([公式:见文]= -0.3294,p)。结论:父母压力与母亲的倦怠水平相关。然而,配偶的支持可能会削弱父母压力和倦怠之间的关系。需要进一步研究配偶支持与职业倦怠之间的关系,并开展与配偶支持相关的认知项目。
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引用次数: 0
Posttraumatic stress disorder, general psychopathology, and suicidality among Yazidi women in Iraq kidnapped and/or raped by ISIS in 2014 2014年被ISIS绑架和/或强奸的伊拉克雅兹迪妇女的创伤后应激障碍、一般精神病理学和自杀倾向。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-05-20 DOI: 10.1007/s00737-025-01594-x
Fuaad Mohammed Freh, Carol S. North

Purpose

The current study investigated the mental health of Yazidi women exposed to kidnapping and sexual violence among Yazidi women survivors of the Islamic State of Iraq and Syria (ISIS) attacks during captivity in the 2014 genocide period in Iraq.

Methods

This cross-sectional population-based study was conducted at the Internal Displaced People (IDP) camps located in the Duhok Governorate, Kurdistan Regional Government of Iraq (KRG). The data were collected from September 2023 to May 2024. The KRG granted the principal researcher and 2 assistants access to 7 of the 18 IDP camps in Duhok. The number of households for inclusion in each camp was selected proportional to the total number of households in each selected camp by division of each camp’s census into the total census of all camps combined, and all adult women > 18 years of age in these households were deemed eligible for participation in the study. The study sample included 215 Yazidi women aged 18 to 41 years. Face-to-face interviewing was conducted by the first author and trained clinical psychologists, following structured questionnaires: a 6-item demographic questionnaire, The Event Scale (ES), Suicidality (3 questions included suicidality ideation, suicide attempt, and suicidal behavior), Posttraumatic Check List for DSM-5 (PCL-5), and General Health Questionnaire-28 (GHQ-28).

Results

Women’s current mental health following rape during captivity revealed risk for posttraumatic stress disorder (PTSD), general psychopathology, and suicidality in association with kidnapping and sexual violence, with odds ratios between 3.11 and 4.89 for the three main variables (PTSD risk, General psychopathology and suicidality) in multivariate models.

Conclusion

It can be concluded that ISIS captivity and wartime rapes had extensive long-term consequences on the mental health of women survivors. The high prevalence of PTSD emphasizes the need for culturally sensitive diagnostic and therapeutic services to address the intermediate and long-term consequences of wartime rape.

目的:本研究调查了2014年伊拉克种族灭绝期间遭受伊拉克和叙利亚伊斯兰国(ISIS)袭击的雅兹迪妇女幸存者中遭受绑架和性暴力的雅兹迪妇女的心理健康状况。方法:这项以人口为基础的横断面研究在位于伊拉克库尔德斯坦地区政府(KRG)杜胡克省的国内流离失所者(IDP)营地进行。数据收集于2023年9月至2024年5月。KRG允许首席研究员和两名助理进入杜胡克18个国内流离失所者营地中的7个。每个营地纳入的家庭数量与每个营地的家庭总数成比例,将每个营地的人口普查分成所有营地的总人口普查,这些家庭中所有18岁以上的成年妇女都被认为有资格参加这项研究。研究样本包括215名年龄在18至41岁之间的雅兹迪妇女。面对面访谈由第一作者和训练有素的临床心理学家进行,采用结构化问卷:6项人口统计问卷、事件量表(ES)、自杀倾向(3个问题包括自杀意念、自杀企图和自杀行为)、DSM-5创伤后检查表(PCL-5)和一般健康问卷-28 (GHQ-28)。结果:在囚禁期间被强奸的妇女的当前心理健康状况揭示了与绑架和性暴力相关的创伤后应激障碍(PTSD)、一般精神病理和自杀的风险,在多变量模型中,三个主要变量(PTSD风险、一般精神病理和自杀)的比值比在3.11和4.89之间。结论:可以得出结论,ISIS囚禁和战时强奸对妇女幸存者的心理健康产生了广泛的长期影响。创伤后应激障碍的高患病率强调需要文化敏感的诊断和治疗服务,以解决战时强奸的中期和长期后果。
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引用次数: 0
Correction to: Clinician-reported childbirth outcomes, patient-reported childbirth trauma, and risk for postpartum depression 更正:临床报告的分娩结果,患者报告的分娩创伤和产后抑郁症的风险。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-05-19 DOI: 10.1007/s00737-025-01595-w
Rebecca Waller, Sara L. Kornfield, Lauren K. White, Barbara H. Chaiyachati, Ran Barzilay, Wanjikũ Njoroge, Julia Parish-Morris, Andrea F. Duncan, Megan M. Himes, Yuheiry Rodriguez, Jakob Seidlitz, Valerie Riis, Heather H. Burris, Raquel E. Gur, Michal A. Elovitz
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引用次数: 0
Effect of combined oral contraceptive use on verbal memory function in healthy women 复方口服避孕药对健康女性言语记忆功能的影响。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-05-19 DOI: 10.1007/s00737-025-01592-z
Mette C. Hochheim, Vibe G. Frokjaer, Søren V. Larsen, Vibeke H. Dam

Purpose

Female sex hormones as well as the synthetic hormones contained within combined oral contraceptives (COCs) may influence emotional and cognitive functioning including learning and memory; however, findings are inconsistent. We here present the largest study to date investigating the effect of COC use on verbal memory in healthy women.

Methods

COC use and verbal memory scores were available from the CIMBI database for 205 healthy women in the reproductive age. We assessed if verbal memory and affective bias differed between COC users and non-users. In a subgroup of natural cycling women in the follicular phase, we assessed if verbal memory was associated with plasma estradiol levels.

Results

We found no statistically significant group differences in either overall memory performance (p = 0.16) or affective memory bias (p = 0.18) between COC users and non-users, although there was a trend suggesting COC users may exhibit slightly better recall for short-term (p = 0.09) and long-term task (p = 0.08) conditions. Similarly, COC users tended to have slightly better overall memory compared with women in the follicular phase (p = 0.05). Follicular phase plasma estradiol levels were not associated with verbal memory.

Conclusions

We found no support for COC use to negatively impact verbal memory, if anything COC users tended to perform better than natural cycling women in follicular phase; however, this could be influenced by a healthy user bias. In conclusion, these findings highlight that women who tolerate COCs well should not be concerned about potential adverse effects on memory.   

目的:女性性激素以及复方口服避孕药(COCs)中所含的合成激素可能影响情绪和认知功能,包括学习和记忆;然而,研究结果并不一致。我们在此提出了迄今为止调查COC使用对健康女性言语记忆影响的最大研究。方法:从CIMBI数据库中获取205名育龄健康妇女的COC使用和言语记忆评分。我们评估了COC使用者和非使用者之间的言语记忆和情感偏差是否存在差异。在卵泡期自然周期女性亚组中,我们评估了言语记忆是否与血浆雌二醇水平相关。结果:我们发现COC使用者和非使用者在整体记忆表现(p = 0.16)或情感记忆偏差(p = 0.18)方面没有统计学上的显著差异,尽管有趋势表明COC使用者可能在短期(p = 0.09)和长期任务(p = 0.08)条件下表现出稍好的回忆。同样,与处于卵泡期的女性相比,COC使用者的整体记忆力略好(p = 0.05)。卵泡期血浆雌二醇水平与言语记忆无关。结论:我们没有发现COC使用对言语记忆有负面影响的证据,如果有的话,COC使用者倾向于在卵泡期比自然循环的女性表现更好;然而,这可能受到健康用户偏见的影响。总之,这些发现强调,对COCs耐受良好的女性不应担心对记忆的潜在不利影响。
{"title":"Effect of combined oral contraceptive use on verbal memory function in healthy women","authors":"Mette C. Hochheim,&nbsp;Vibe G. Frokjaer,&nbsp;Søren V. Larsen,&nbsp;Vibeke H. Dam","doi":"10.1007/s00737-025-01592-z","DOIUrl":"10.1007/s00737-025-01592-z","url":null,"abstract":"<div><h3>Purpose</h3><p>Female sex hormones as well as the synthetic hormones contained within combined oral contraceptives (COCs) may influence emotional and cognitive functioning including learning and memory; however, findings are inconsistent. We here present the largest study to date investigating the effect of COC use on verbal memory in healthy women.</p><h3>Methods</h3><p>COC use and verbal memory scores were available from the CIMBI database for 205 healthy women in the reproductive age. We assessed if verbal memory and affective bias differed between COC users and non-users. In a subgroup of natural cycling women in the follicular phase, we assessed if verbal memory was associated with plasma estradiol levels.</p><h3>Results</h3><p>We found no statistically significant group differences in either overall memory performance (<i>p</i> = 0.16) or affective memory bias (<i>p</i> = 0.18) between COC users and non-users, although there was a trend suggesting COC users may exhibit slightly better recall for short-term (<i>p</i> = 0.09) and long-term task (<i>p</i> = 0.08) conditions. Similarly, COC users tended to have slightly better overall memory compared with women in the follicular phase (<i>p</i> = 0.05). Follicular phase plasma estradiol levels were not associated with verbal memory.</p><h3>Conclusions</h3><p>We found no support for COC use to negatively impact verbal memory, if anything COC users tended to perform better than natural cycling women in follicular phase; however, this could be influenced by a healthy user bias. In conclusion, these findings highlight that women who tolerate COCs well should not be concerned about potential adverse effects on memory.   </p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"28 5","pages":"1211 - 1219"},"PeriodicalIF":2.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-025-01592-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving inpatient postpartum depression screening: results from a quality improvement initiative 改善住院产后抑郁症筛查:结果从质量改进倡议。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-05-15 DOI: 10.1007/s00737-025-01591-0
Rebecca Woofter, Gwendolyn Hill, Emily Wong, Tiffani J. Bright, Catherine Bresee, Sarah J. Kilpatrick, Eynav E. Accortt

Purpose

Screening is necessary to identify patients with postpartum depression or anxiety and facilitate access to mental healthcare. This study evaluated a quality improvement initiative for inpatient postpartum depression screening, which was implemented to better identify patients in need of mental healthcare. This initiative replaced the Patient Health Questionnaire (PHQ-9) administered verbally by nurses with the Edinburgh Postnatal Depression Scale (EPDS-10) self-administered by patients via iPads.

Methods

Electronic medical records for patients who delivered June 2020-October 2023 at Cedars-Sinai were analyzed (N = 17,403). Differences in completed screenings, positive depression screenings, suicidal ideation, and social work referrals before and after the initiative were examined with chi-square tests and multiple logistic regression models. Factors associated with positive anxiety screenings on the EPDS-10 were also identified.

Results

Overall, 98.6% of patients completed depression screenings. Among those who completed screenings, positive depression screenings increased from 4.0 to 11.4%, identified suicidal ideation increased from 0.2 to 1.1%, and social work referrals increased from 64.1 to 84.0%, before and after the initiative. Post-initiative, patients had higher odds of positive depression screenings, indicating suicidal ideation, and receiving social work referrals compared to pre-initiative. Among those who completed EPDS-10 screenings, 31% were positive for anxiety.

Conclusions

Compared to the PHQ-9 administered verbally by nurses, the EPDS-10 self-administered by patients via iPads resulted in higher rates of positive depression screenings, identified suicidal ideation, and social work referrals. It is imperative to accurately screen patients for postpartum depression and anxiety to facilitate access to mental healthcare and address morbidity and mortality.

Clinical trial number

Not applicable.

目的:筛查是必要的,以识别产后抑郁或焦虑患者,并促进获得心理保健。本研究评估了住院产后抑郁症筛查的质量改进倡议,该倡议的实施是为了更好地识别需要心理保健的患者。这一举措取代了由护士口头填写的患者健康问卷(PHQ-9),取而代之的是由患者通过ipad自行填写的爱丁堡产后抑郁量表(EPDS-10)。方法:对雪松西奈医院2020年6月至2023年10月分娩的患者的电子病历进行分析(N = 17,403)。采用卡方检验和多元logistic回归模型检验了主动行动前后完成筛查、积极抑郁筛查、自杀意念和社会工作转介的差异。与EPDS-10阳性焦虑筛查相关的因素也被确定。结果:总体而言,98.6%的患者完成了抑郁症筛查。在完成筛检的人当中,主动行动前后,积极抑郁筛检率从4.0%上升到11.4%,确定自杀意念率从0.2%上升到1.1%,社会工作转介率从64.1%上升到84.0%。与主动治疗前相比,主动治疗后,患者有更高的几率进行积极的抑郁筛查,表明有自杀念头,并接受社会工作转介。在完成EPDS-10筛查的人中,31%的人焦虑呈阳性。结论:与护士口头给药的PHQ-9相比,患者通过ipad自我给药的EPDS-10有更高的积极抑郁筛查率、确定的自杀意念率和社会工作转介率。必须准确筛查产后抑郁和焦虑患者,以促进获得精神保健并解决发病率和死亡率问题。临床试验号:不适用。
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引用次数: 0
Peripartum substance use and punitive laws: an update 围产期药物使用和惩罚性法律:最新进展。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-05-14 DOI: 10.1007/s00737-025-01590-1
Wesley R. White, Evanna M. Ojeda, Jenna R. Ronquest, Victoria P. Scott, Samuel J. House, Clare C. Brown, Zachary N. Stowe, Jessica L. Coker

This is a follow up on a 2016 article discussing the rise in punitive perinatal substance use laws. From 2016–2023, there has been a 39% increase in laws equating perinatal substance use with child abuse, and a 73% increase in mandated reporting laws, despite limited evidence that these laws are helpful. We write this update to raise awareness for providers, so they may better counsel patients on this topic and help advocate for treatment focused policies in their state.

这是2016年一篇讨论惩罚性围产期药物使用法律增加的文章的后续文章。从2016年到2023年,将围产期药物使用与虐待儿童等同起来的法律增加了39%,强制性报告法律增加了73%,尽管证据有限,这些法律是有帮助的。我们写这篇更新是为了提高提供者的意识,这样他们就可以更好地就这个话题向患者提供咨询,并帮助倡导他们所在州的以治疗为重点的政策。
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引用次数: 0
Psychiatric disorders, impulsivity and borderline personality in patients with polycystic ovary syndrome 多囊卵巢综合征患者的精神障碍、冲动和边缘型人格。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-05-06 DOI: 10.1007/s00737-025-01589-8
Mariwan Husni, Diaa E. E. Rizk, Nawal Saad Alabdulla, Aldana Zayed, Hosni Malas, Nourah Adbulaziz Modahka, Sabeeka Jamal Alqujan, Basma Khalid Alansari, Shaika Ebrahim Alhajri, Nada Mahmood, Haitham Jahrami

Introduction

Polycystic ovarian syndrome (PCOS) is a common endocrine condition in women. Studies have shown that PCOS is associated with poor quality of life, anxiety, sadness, dissatisfaction with one's appearance, and sexual dysfunction.

Objective

This study was conducted to determine whether a strong psycho-pathological personality is related to PCOS and whether this personality is related to the hyperandrogenic state.

Methods

Anthropometric, metabolic, hormonal, clinical, and psychological characteristics were examined in 90 Bahraini women with PCOS. After confirming the diagnosis of PCOS via Rotterdam criteria, including ovarian ultrasound, each patient was evaluated via the following questionnaires: 1) the GAD-7 (General Anxiety Disorder-7) to measure the severity of anxiety; 2) the Patient Health Questionnaire-9 (PHQ-9) to confirm and measure the severity of depression; 3) the Barratt Impulsiveness Scale (BIS‐11) to measure aggression; and 4) the McLean Screening Instrument to identify borderline personality disorders (MSI-BPDs). The study was approved by the Institutional Review Board.

Results

Compared to controls, PCOS patients exhibited significantly higher rates of severe depression (8% vs. 0%, p < 0.001), severe anxiety (7% vs. 0%, p < 0.001), impulsivity (BIS-11: 39.43 ± 9.69 vs. 26.64 ± 2.92, p < 0.001), and borderline personality traits (McLean: 2.41 ± 2.44 vs. 1.2 ± 0.94, p < 0.001). Metabolic comorbidities, including obesity (BMI 28.88 vs. 20.27, p < 0.001) and hypothyroidism (48% vs. 0%, p < 0.001), were prevalent in PCOS. Hyperandrogenism correlated weakly with psychiatric outcomes (all p > 0.05).

Conclusion

Women with PCOS demonstrate markedly elevated psychiatric and medical burdens compared to healthy controls. While hyperandrogenism showed limited direct associations, metabolic dysfunction (e.g., obesity) may mediate psychiatric risk. These findings underscore the need for multidisciplinary care integrating psychological and endocrine management, particularly in populations where cultural norms exacerbate PCOS-related distress.

简介:多囊卵巢综合征(PCOS)是一种常见的女性内分泌疾病。研究表明,多囊卵巢综合征与生活质量差、焦虑、悲伤、对自己的外表不满和性功能障碍有关。目的:探讨强烈的心理病理人格是否与PCOS有关,以及这种人格是否与高雄激素状态有关。方法:对90例巴林多囊卵巢综合征(PCOS)患者进行人体测量、代谢、激素、临床和心理特征的检测。经包括卵巢超声检查在内的鹿特丹标准确诊PCOS后,通过以下问卷对患者进行评估:1)GAD-7 (General Anxiety Disorder-7),衡量焦虑的严重程度;2)采用患者健康问卷-9 (PHQ-9)确认和测量抑郁的严重程度;3) Barratt冲动性量表(BIS-11)测量攻击性;4)边缘型人格障碍(msi - bpd)的McLean筛查工具。这项研究得到了机构审查委员会的批准。结果:与对照组相比,PCOS患者表现出明显更高的严重抑郁发生率(8%比0%,p 0.05)。结论:与健康对照相比,PCOS患者的精神和医疗负担明显增加。虽然高雄激素血症显示有限的直接关联,但代谢功能障碍(如肥胖)可能介导精神风险。这些发现强调了综合心理和内分泌管理的多学科护理的必要性,特别是在文化规范加剧多囊卵巢综合征相关痛苦的人群中。
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引用次数: 0
A retrospective chart review study of patients treated in a hospital-based brexanolone program 一项基于医院的布雷沙诺酮方案治疗患者的回顾性图表回顾研究。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-05-02 DOI: 10.1007/s00737-025-01588-9
Zobeida M. Diaz, Margaret M. Howard, Keyline V. Moreno, Madilyn G. Halwes, Cynthia L. Battle

Purpose

Postpartum depression (PPD), the most common childbirth complication in the United States, can be treated using brexanolone, an intravenous form of allopregnanolone.

Methods

This retrospective chart review study evaluated clinical outcomes of 64 postpartum women who received brexanolone infusion for PPD in a real-world setting.

Results

Treatment was associated with improved depression and anxiety symptoms, and 71% of patients reported significant improvement in their PPD.

Conclusions

While further research is needed, this study supports brexanolone as an efficacious treatment for PPD.

目的:产后抑郁症(PPD)是美国最常见的分娩并发症,可以使用布雷沙诺酮治疗,布雷沙诺酮是一种静脉注射的异孕酮。方法:本回顾性图表回顾研究评估了64名产后妇女在现实世界中接受布雷沙诺酮输注治疗PPD的临床结果。结果:治疗与抑郁和焦虑症状的改善有关,71%的患者报告他们的PPD有显著改善。结论:虽然需要进一步的研究,但本研究支持布雷沙诺酮是治疗PPD的有效方法。
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引用次数: 0
Forensic aspects of reproductive mental health: editorial 生殖心理健康的法医方面:编辑。
IF 3.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-04-25 DOI: 10.1007/s00737-025-01587-w
Diana Barnes, Jane Fisher
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引用次数: 0
期刊
Archives of Women's Mental Health
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