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A retrospective study on hearing outcomes of infants of COVID-19 mothers pre-vaccination era 关于 COVID-19 疫苗接种前母亲所生婴儿听力结果的回顾性研究
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.62851
Shenbagavalli S, Ashok Kumar Subramaniyam, Yuvaraj Radhakrishnan, Thalapathy Ramkumar, Venkatesan R, Manisha T
Background: A COVID-19 infection can result in a variety of symptoms. Findings must be carefully reviewed because there is still a dispute over the potential involvement of the audiovestibular system. Moreover, there is debate over the intrauterine transfer of COVID-19 infection from mother to fetus in pregnant people. There are not many investigations on the audiovestibular symptomatology of infants exposed to COVID-19 during pregnancy.Aims and Objectives: This study looks at any potential links between the COVID-19 gestational infection and the start of hearing impairment in babies. The verification of hearing’s engagement in COVID-19 allows for the planning of the time and methods for children’s audiological evaluations.Materials and Methods: Newborns had audiological examination and screening for hearing loss. The automatic transient evoked otoacoustic emissions (OAEs) test is used to evaluate newborns for hearing impairments before they are released from the hospital. By employing the COVID-19 case history, otoscopy, acoustic immittance test, transient evoked OAEs test, and mother, pregnancy, and perinatal case histories, an audiological examination is conducted on children under 3 months of age, with 2 weeks, 1 month and 3 months of age follow-up.Results: The research comprised 100 children. Of these infants, 90% were part of the neonatal hearing screening initiative. Due to isolation protocols, the remaining 10 neonates did not undergo hearing screening; instead, a direct audiological examination was performed on them. Out of the 90 newborns that were tested, only 11 had a bilateral REFER test result, but the audiological examination revealed a normal hearing threshold.Conclusion: There is no data in this study that a mother’s COVID-19 infection results in hearing loss in newborn.
背景:COVID-19 感染可导致多种症状。由于对听觉前庭系统是否可能受到感染仍存在争议,因此必须仔细审查研究结果。此外,关于 COVID-19 感染是否会在孕妇宫内从母体传给胎儿的问题也存在争议。关于孕期接触 COVID-19 的婴儿的听觉前庭症状的调查并不多:本研究探讨 COVID-19 妊娠感染与婴儿开始出现听力障碍之间的任何潜在联系。通过验证听力与 COVID-19 的关系,可以规划儿童听力评估的时间和方法:新生儿进行听力检查和听力损失筛查。自动瞬态诱发耳声发射(OAE)测试用于新生儿出院前的听力障碍评估。通过采用 COVID-19 病史、耳镜检查、声导抗测试、瞬态诱发 OAEs 测试以及母亲、孕期和围产期病史,对 3 个月以下的儿童进行听力检查,并在 2 周、1 个月和 3 个月后进行随访:研究包括 100 名儿童。其中 90% 的婴儿参加了新生儿听力筛查计划。由于隔离协议的原因,其余 10 名新生儿没有接受听力筛查,而是直接进行了听力检查。在接受测试的 90 名新生儿中,只有 11 名新生儿的双侧 REFER 测试结果正常,但听力检查结果显示听阈正常:结论:本研究没有数据表明母亲感染 COVID-19 会导致新生儿听力损失。
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引用次数: 0
Clinical pattern of vernal keratoconjunctivitis in children – A cross-sectional study 儿童春季角结膜炎的临床模式 - 一项横断面研究
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.65894
Roopa K, Ramalakshmi Badugu, SreeLakshmi Pallamreddy, Suhasini J
Background: Vernal keratoconjunctivitis (VKC), a chronic and bilateral allergic eye condition, predominantly affects young males and is more prevalent in hot, humid regions with high allergen exposure. It manifests with itching, light sensitivity, burning sensations, and tearing. The three main clinical forms include limbal or bulbar, palpebral or tarsal, and mixed presentations.Aims and Objectives: This study aimed to describe the clinical patterns of VKC in children at a tertiary care hospital in Andhra Pradesh.Materials and Methods: This cross-sectional observational study was conducted in a hospital setting at the Department of Ophthalmology, SV Medical College in Tirupati, Andhra Pradesh, between January 2021 and January 2022. Ninety children aged 5–12 years with symptoms of allergic conjunctivitis were enrolled in the study. The Bonini grading system was used to grade the severity of the disease based on clinical manifestations at the time of initial presentation.Results: Mean age of disease onset was 8.6±2.3 years, with a male-to-female ratio (M: F) of 2.1:1. The majority of the subjects experienced seasonal occurrence 69 (77.0%), whereas 21 (23%) had perennial occurrence. The commonly reported symptoms included itching (83%), redness (73%), watering (73%), and discharge (47%). A significant number of patients (60, 69%) had a mixed type of disease that affected both the tarsal and bulbar conjunctiva.Conclusion: VKC predominantly affects young males, displaying a seasonal distribution and showing less allergic association, consistent with patterns observed in other tropical regions. Most patients had mild VKC at presentation, and a mixed-form pattern was most frequently observed.
背景:春季角膜结膜炎(VKC)是一种慢性双侧过敏性眼病,主要影响年轻男性,在炎热潮湿、过敏原接触较多的地区发病率较高。它表现为瘙痒、光敏感、烧灼感和流泪。三种主要的临床表现形式包括边缘或球部、睑部或跗部以及混合表现:本研究旨在描述安得拉邦一家三级医院中儿童 VKC 的临床模式:这项横断面观察性研究于 2021 年 1 月至 2022 年 1 月在安得拉邦蒂鲁帕蒂 SV 医学院眼科系的医院环境中进行。研究共招募了 90 名有过敏性结膜炎症状的 5-12 岁儿童。根据初次发病时的临床表现,采用博尼尼分级系统对疾病的严重程度进行分级:平均发病年龄为(8.6±2.3)岁,男女比例(男:女)为 2.1:1。大多数受试者为季节性发病,69 人(77.0%),21 人(23%)为常年性发病。常见症状包括瘙痒(83%)、发红(73%)、流泪(73%)和分泌物(47%)。相当多的患者(60,69%)患有混合型疾病,同时影响跗骨结膜和球结膜:结论:VKC 主要影响年轻男性,呈季节性分布,与过敏相关性较低,这与在其他热带地区观察到的模式一致。大多数患者在发病时都有轻微的 VKC,而且最常见的是混合型。
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引用次数: 0
Association between suction tip culture and surgical site infection in elective clean orthopedic lower limb surgeries 下肢骨科择期清洁手术中吸头培养与手术部位感染之间的关系
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.64883
Adam Zaneen, Jeevan Pereira, Neha Heswani
Background: Surgical site infections (SSIs) can be caused by various factors, including contamination of the surgical field. Perioperative cultures can be employed in clean orthopedic procedures to detect bacterial contamination that may occur during surgery.Aims and Objectives: The study aimed to evaluate the correlation between suction tip cultures and surgical wounds in clean orthopedic surgeries.Materials and Methods: A cross-sectional study was conducted at Yenepoya Medical College Hospital, Mangalore, Karnataka, with 250 patients in whom drain tips were sent for culture and followed up for 3 months to assess for SSI. Skin commensals from the nasal and groin samples were analyzed for the presence of bacteria.Results: A total of 250 patients meeting the inclusion and exclusion criteria were included. Thirty patients were positive for drain tip culture, and 12 (4.8%) patients had SSI during the 3rd month follow-up period, showing a statistically significant relationship between drain tip culture and SSIs (P=0.001). Skin commensals constituted 67% (nasal) and 100% in the groin of perioperative contaminants, accounting for 4.8% of SSIs.Conclusion: Suction drain tip culture and skin commensal analysis may be good predictors of SSIs. Intraoperative surgical site contaminants can be identified using perioperative cultures. Timely administration of suitable antibiotics and local wound care for perioperative contamination can help minimize the incidence of SSI.
背景:手术部位感染(SSI)可由多种因素引起,包括手术区域污染。在清洁骨科手术中,围手术期培养可用于检测手术过程中可能发生的细菌污染:本研究旨在评估清洁骨科手术中吸头培养与手术伤口之间的相关性:在卡纳塔克邦芒格洛尔的耶内波亚医学院医院进行了一项横断面研究,对 250 名患者的引流管尖端进行培养,并随访 3 个月以评估 SSI。对鼻腔和腹股沟样本中的皮肤共生菌进行了分析:共有 250 名患者符合纳入和排除标准。30 名患者的引流管尖端培养呈阳性,12 名(4.8%)患者在随访的第 3 个月中出现了 SSI,显示引流管尖端培养与 SSI 之间存在显著的统计学关系(P=0.001)。皮肤共生菌占围术期污染物的67%(鼻腔)和100%(腹股沟),占SSI的4.8%:结论:抽吸引流管尖端培养和皮肤共生菌分析可能是预测SSI的良好指标。通过围手术期培养可确定术中手术部位污染物。针对围手术期污染及时使用合适的抗生素并进行局部伤口护理,有助于将 SSI 的发生率降至最低。
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引用次数: 0
Evaluation of different modalities in prevention of seroma formation post-modified radical mastectomy – An observational study from a rural tertiary care center 改良根治性乳房切除术后预防血清肿形成的不同方法评估 - 一项来自农村三级医疗中心的观察研究
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.63706
Bibaswan Chakrabarty, J. B. Samaddar, Dwaipayan Samaddar, Debasis Ray
Background: Seroma, a recognized complication of modified radical mastectomy (MRM) delays the administration of adjuvant therapy and also effects adverse events.Aims and Objectives: This study was conducted to study the sociodemographic and clinical profile of patients developing seroma post MRM and compare the effectiveness of different modalities of seroma prevention since there is a dearth of literature on this matter in our sub-Himalayan region.Materials and Methods: This was an observational study conducted from February 2021 to August 2022 on 60 women with carcinoma breast who underwent MRM. They were studied for sociodemographic profile, cancer characteristics, and seroma prevention techniques and followed up during the study period. Preventive modalities used were quilting, octreotide therapy, suction drains with early drain removal, passive low suction drains, sharp dissection technique, and sclerotherapy. The results were analyzed using the Statistical Package for the Social Sciences version 22.Results: The mean age was 49.7±9.4 years, 18.3% had hypertension and 10.0% diabetes mellitus, and 58.3% presented with breast lump. Overall incidence of seroma was 23.3%; the highest was observed in sclerotherapy (50%), and the lowest was in quilting (7.1%) (P=0.235). The presence of hypertension (P=0.026) and the non-administration of neoadjuvant chemotherapy (P=0.010) was significantly associated with developing seroma. Sharp dissection was associated with wound infection (33.3%), sclerotherapy with flap necrosis (50%), and quilting with shoulder stiffness (21.4%).Conclusion: The lowest incidence of seroma was in quilting and the highest in sclerotherapy. Adverse events such as wound infection, shoulder stiffness, and flap necrosis were the lowest among patients discharged with passive drains and highest in sclerotherapy.
背景:血清肿是改良根治性乳房切除术(MRM)的一种公认并发症,会延误辅助治疗的实施,还会造成不良事件:本研究旨在研究 MRM 术后血清肿患者的社会人口学和临床概况,并比较不同血清肿预防方式的有效性,因为在我们喜马拉雅山以南地区缺乏这方面的文献:这是一项观察性研究,研究时间为 2021 年 2 月至 2022 年 8 月,对象是 60 名接受 MRM 的乳腺癌妇女。在研究期间,对她们的社会人口学特征、癌症特征和血清肿预防技术进行了研究和随访。使用的预防方法包括绗缝、奥曲肽疗法、早期移除引流管的抽吸引流、被动低抽吸引流、锐利剥离技术和硬化剂疗法。结果采用社会科学统计软件包 22 版进行分析:平均年龄为(49.7±9.4)岁,18.3%患有高血压,10.0%患有糖尿病,58.3%伴有乳房肿块。血清肿的总发生率为 23.3%,其中硬化剂治疗的发生率最高(50%),绗缝治疗的发生率最低(7.1%)(P=0.235)。高血压(P=0.026)和未进行新辅助化疗(P=0.010)与血清肿的发生有显著相关性。锐性剥离与伤口感染有关(33.3%),硬化治疗与皮瓣坏死有关(50%),绗缝与肩部僵硬有关(21.4%):结论:血清肿发生率最低的是绗缝,最高的是硬化剂注射。带被动引流管出院的患者中,伤口感染、肩部僵硬和皮瓣坏死等不良事件发生率最低,而硬化剂治疗的发生率最高。
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引用次数: 0
Comparison of conventional percutaneous nephrolithotomy versus endoscopic combined intrarenal surgery in complex renal calculus – Our institutional experience 传统经皮肾镜取石术与内镜联合肾内手术治疗复杂肾结石的比较 - 本机构的经验
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.64061
Rajasekar Maruthamuthu, Jayaprakash Narashimman, Mahendran Ganesamoorthy, P. Thiruvarul, Prasad Sivasamy
Background: Complex renal calculi, characterized by their size, location, and composition, pose a significant challenge to urologists due to the potential for complications and the difficulty in achieving complete stone clearance. Conventional percutaneous nephrolithotomy (PCNL) and endoscopic combined intrarenal surgery (ECIRS) are two established techniques for managing these complex renal calculi.Aims and Objectives: The aims and objectives are to compare the effectiveness, safety, and outcomes of PCNL versus ECIRS in managing complex renal calculi in a cohort of 60 cases treated at GMKMCH-Salem.Materials and Methods: A retrospective analysis was conducted on 60 patients with complex renal calculi who underwent either conventional PCNL or ECIRS during a specified period at GMKMCH-Salem. Patient demographics, stone characteristics, procedural details, intraoperative and post-operative parameters, and complications were analyzed and compared between the two treatment groups.Results: The study found that both PCNL and ECIRS techniques were effective in treating complex renal calculi. However, significant differences were observed between the two groups in terms of outcomes. The ECIRS technique exhibited superior outcomes with higher stone clearance rates (P<0.001), shorter operative times (P<0.05), and reduced hospital stays (P<0.05) compared to conventional PCNL.Conclusion: This study demonstrates that ECIRS is a promising alternative to conventional PCNL in the management of complex renal calculi. The ECIRS technique yielded higher stone clearance rates, shorter operative times, and reduced hospital stays, potentially improving patient outcomes and reducing health-care costs. Although our findings show favorable results for ECIRS, the decision between conventional PCNL and ECIRS should be based on individual patient characteristics, surgeon expertise, and resource availability.
背景:复杂肾结石的特点是大小、位置和成分复杂,由于其潜在的并发症和难以彻底清除结石,给泌尿科医生带来了巨大挑战。传统的经皮肾镜取石术(PCNL)和内镜联合肾内手术(ECIRS)是治疗这些复杂肾结石的两种成熟技术:目的和目标:比较 PCNL 和 ECIRS 在治疗复杂肾结石方面的有效性、安全性和结果:我们对 60 例复杂肾结石患者进行了回顾性分析,这些患者在 GMKMCH-Salem 的特定时期接受了传统 PCNL 或 ECIRS 治疗。对两组患者的人口统计学、结石特征、手术细节、术中和术后参数以及并发症进行了分析和比较:研究发现,PCNL 和 ECIRS 技术都能有效治疗复杂性肾结石。结果:研究发现 PCNL 和 ECIRS 技术都能有效治疗复杂性肾结石。与传统 PCNL 相比,ECIRS 技术的疗效更佳,结石清除率更高(P<0.001),手术时间更短(P<0.05),住院时间更短(P<0.05):本研究表明,在治疗复杂性肾结石时,ECIRS 是一种替代传统 PCNL 的有效方法。ECIRS技术的结石清除率更高、手术时间更短、住院时间更短,可能改善患者预后并降低医疗成本。虽然我们的研究结果表明ECIRS的效果良好,但在选择传统PCNL还是ECIRS时,应根据患者的个体特征、外科医生的专业技能和资源的可用性来决定。
{"title":"Comparison of conventional percutaneous nephrolithotomy versus endoscopic combined intrarenal surgery in complex renal calculus – Our institutional experience","authors":"Rajasekar Maruthamuthu, Jayaprakash Narashimman, Mahendran Ganesamoorthy, P. Thiruvarul, Prasad Sivasamy","doi":"10.3126/ajms.v15i7.64061","DOIUrl":"https://doi.org/10.3126/ajms.v15i7.64061","url":null,"abstract":"Background: Complex renal calculi, characterized by their size, location, and composition, pose a significant challenge to urologists due to the potential for complications and the difficulty in achieving complete stone clearance. Conventional percutaneous nephrolithotomy (PCNL) and endoscopic combined intrarenal surgery (ECIRS) are two established techniques for managing these complex renal calculi.\u0000Aims and Objectives: The aims and objectives are to compare the effectiveness, safety, and outcomes of PCNL versus ECIRS in managing complex renal calculi in a cohort of 60 cases treated at GMKMCH-Salem.\u0000Materials and Methods: A retrospective analysis was conducted on 60 patients with complex renal calculi who underwent either conventional PCNL or ECIRS during a specified period at GMKMCH-Salem. Patient demographics, stone characteristics, procedural details, intraoperative and post-operative parameters, and complications were analyzed and compared between the two treatment groups.\u0000Results: The study found that both PCNL and ECIRS techniques were effective in treating complex renal calculi. However, significant differences were observed between the two groups in terms of outcomes. The ECIRS technique exhibited superior outcomes with higher stone clearance rates (P<0.001), shorter operative times (P<0.05), and reduced hospital stays (P<0.05) compared to conventional PCNL.\u0000Conclusion: This study demonstrates that ECIRS is a promising alternative to conventional PCNL in the management of complex renal calculi. The ECIRS technique yielded higher stone clearance rates, shorter operative times, and reduced hospital stays, potentially improving patient outcomes and reducing health-care costs. Although our findings show favorable results for ECIRS, the decision between conventional PCNL and ECIRS should be based on individual patient characteristics, surgeon expertise, and resource availability.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141711189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of operative outcome of open versus laparoscopic inguinal hernia in rural tertiary care hospital in Haryana: A randomized controlled study 哈里亚纳邦农村三级医院腹股沟疝开腹与腹腔镜手术效果比较:随机对照研究
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.64059
Sanjeev Singla, P. Bansal, Garima Dwivedi, Madhan Pranesh, Chanderbhan
Background: Hernia surgery is one of the commonly done procedures in General surgery. A hernia is defined as an abnormal protrusion of an organ or tissue through a defect in its surrounding walls.Aims and Objectives: Comparison of morbidity in terms of total analgesic usage, mean length of hospital stay, comparison among open and TEP repair of hernias in primary inguinal hernias among males.Material and Methods: This study was done on 80 patients with clinical diagnosis of primary inguinal hernia over a period of one year to compare the result of two surgeries, open lichenstein repair (n=40) and TEP repair (n=40).Results: Postoperative pain using VAS was found to be lower in patients having laparoscopic TEP hernia repair when compared to open lichenstein tension free repair (p <0.01). Operating time was observed to be more with TEP group with mean of 59 ± 17.02 minutes compared with open group which had mean of 44.92±12 minutes. Mean number of analgesic in open cases was 6.65 ± 1.81 whereas in case of TEP group it was 4.35±1.47 over a period of one month.Conclusion: Lichtenstein tension free mesh hernioplasty still remains the gold standard operation done for inguinal hernia. TEP repair has proven to be superior in terms of perioperative hemorrhage and post-operative analgesia requirement. Study concluded that laparoscopic TEP repair of inguinal repair have a considerable clinical advantage over open hernia repair in terms of postoperative pain and analgesia requirement, hospital stay and postoperative complications.
背景:疝气手术是普外科常见的手术之一。疝气的定义是器官或组织通过其周围壁的缺陷异常突出:比较男性原发性腹股沟疝的总镇痛剂用量、平均住院时间、开放式疝修补术和 TEP 修补术的发病率:本研究对 80 名临床诊断为原发性腹股沟疝的患者进行了为期一年的研究,以比较两种手术(开放式 Lichenstein 修补术(40 人)和 TEP 修补术(40 人))的结果:结果:与开放式Lichenstein无张力修补术相比,腹腔镜TEP疝修补术患者的术后疼痛程度(VAS)更低(P <0.01)。腹腔镜 TEP 组的平均手术时间为(59±17.02)分钟,而开腹组的平均手术时间为(44.92±12)分钟。在一个月的时间里,开腹手术的平均镇痛次数为(6.65±1.81)次,而 TEP 组为(4.35±1.47)次:Lichtenstein无张力网疝成形术仍是治疗腹股沟疝的金标准手术。事实证明,TEP修补术在围手术期出血量和术后镇痛需求方面更胜一筹。研究得出结论,腹腔镜 TEP 腹股沟修补术在术后疼痛和镇痛需求、住院时间和术后并发症方面比开腹疝修补术具有相当大的临床优势。
{"title":"Comparison of operative outcome of open versus laparoscopic inguinal hernia in rural tertiary care hospital in Haryana: A randomized controlled study","authors":"Sanjeev Singla, P. Bansal, Garima Dwivedi, Madhan Pranesh, Chanderbhan","doi":"10.3126/ajms.v15i7.64059","DOIUrl":"https://doi.org/10.3126/ajms.v15i7.64059","url":null,"abstract":"Background: Hernia surgery is one of the commonly done procedures in General surgery. A hernia is defined as an abnormal protrusion of an organ or tissue through a defect in its surrounding walls.\u0000Aims and Objectives: Comparison of morbidity in terms of total analgesic usage, mean length of hospital stay, comparison among open and TEP repair of hernias in primary inguinal hernias among males.\u0000Material and Methods: This study was done on 80 patients with clinical diagnosis of primary inguinal hernia over a period of one year to compare the result of two surgeries, open lichenstein repair (n=40) and TEP repair (n=40).\u0000Results: Postoperative pain using VAS was found to be lower in patients having laparoscopic TEP hernia repair when compared to open lichenstein tension free repair (p <0.01). Operating time was observed to be more with TEP group with mean of 59 ± 17.02 minutes compared with open group which had mean of 44.92±12 minutes. Mean number of analgesic in open cases was 6.65 ± 1.81 whereas in case of TEP group it was 4.35±1.47 over a period of one month.\u0000Conclusion: Lichtenstein tension free mesh hernioplasty still remains the gold standard operation done for inguinal hernia. TEP repair has proven to be superior in terms of perioperative hemorrhage and post-operative analgesia requirement. Study concluded that laparoscopic TEP repair of inguinal repair have a considerable clinical advantage over open hernia repair in terms of postoperative pain and analgesia requirement, hospital stay and postoperative complications.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141711984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual versus conventional cardiac resynchronization: A pilot study 双通道与传统心脏再同步:试点研究
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.65304
Pradip Kumar Ghoshal, Subhraprakash Pramanik, Tanmoy Kanti Goswami, Rajarshi Mondal, A. Biswas, Asish Biswas
Background: Systolic heart failure treatment now includes cardiac resynchronization therapy (CRT) as a necessary element. CRT has been shown to have advantageous impacts on mortality, hospitalization rates, and quality of life. Approximately 30% of patients fail to respond to traditional CRT implantation.Aims and Objectives: This study aimed to compare the outcome of dual resynchronization by placing the right ventricular pacing lead at His bundle or left bundle branch area against conventional CRT.Materials and Methods: This longitudinal follow-up study of a total of 35 patients undergoing CRT device placement for assessment of safety, efficacy, and feasibility of the procedure and post-procedural complications and correlation with parameters obtained from electrocardiogram and echocardiography parameters in a tertiary care set up in India.Results: Among this matched population (mean age 64 years) there was a higher responder rate with the newer technique of dual resynchronization compared to conventional CRT (83% vs. 70%).Conclusion: Dual resynchronization therapy is feasible and safe and provides better electrical resynchronization compared to conventional CRT and could be a better alternative, especially when suboptimal electrical resynchronization is obtained.
背景:目前,收缩性心力衰竭的治疗包括心脏再同步化治疗(CRT),这是一种必要的治疗手段。事实证明,CRT 对死亡率、住院率和生活质量都有有利影响。约有 30% 的患者对传统的 CRT 植入术无效:本研究旨在比较将右室起搏导线置于 His 束或左束支区与传统 CRT 的双重再同步化效果:这项纵向随访研究在印度的一家三级医疗机构进行,共对 35 名接受 CRT 装置置入术的患者进行了随访,以评估手术的安全性、有效性和可行性以及术后并发症,并与心电图和超声心动图参数中获得的参数进行对比:结果:在这一匹配人群(平均年龄 64 岁)中,双再同步化新技术的应答率高于传统 CRT(83% 对 70%):结论:双重再同步化疗法是可行且安全的,与传统的 CRT 相比,它能提供更好的电再同步化,尤其是在电再同步化效果不理想的情况下,它可能是更好的替代疗法。
{"title":"Dual versus conventional cardiac resynchronization: A pilot study","authors":"Pradip Kumar Ghoshal, Subhraprakash Pramanik, Tanmoy Kanti Goswami, Rajarshi Mondal, A. Biswas, Asish Biswas","doi":"10.3126/ajms.v15i7.65304","DOIUrl":"https://doi.org/10.3126/ajms.v15i7.65304","url":null,"abstract":"Background: Systolic heart failure treatment now includes cardiac resynchronization therapy (CRT) as a necessary element. CRT has been shown to have advantageous impacts on mortality, hospitalization rates, and quality of life. Approximately 30% of patients fail to respond to traditional CRT implantation.\u0000Aims and Objectives: This study aimed to compare the outcome of dual resynchronization by placing the right ventricular pacing lead at His bundle or left bundle branch area against conventional CRT.\u0000Materials and Methods: This longitudinal follow-up study of a total of 35 patients undergoing CRT device placement for assessment of safety, efficacy, and feasibility of the procedure and post-procedural complications and correlation with parameters obtained from electrocardiogram and echocardiography parameters in a tertiary care set up in India.\u0000Results: Among this matched population (mean age 64 years) there was a higher responder rate with the newer technique of dual resynchronization compared to conventional CRT (83% vs. 70%).\u0000Conclusion: Dual resynchronization therapy is feasible and safe and provides better electrical resynchronization compared to conventional CRT and could be a better alternative, especially when suboptimal electrical resynchronization is obtained.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The first case report on maturity-onset diabetes of young-11 from West Bengal, India 印度西孟加拉邦首例 11 岁青少年成熟期糖尿病病例报告
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.66031
Manojit Sarkar
Maturity-onset diabetes of young (MODY) is a clinically group of heterogeneous disorder characterized by non-insulin-dependent diabetes diagnosed at a young age (<25 years) with autosomal dominant transmission and lack of autoantibodies. This case report is on MODY in a 30-day-old baby. The patient also has an umbilical hernia and choledochal cyst. We present an instance of 30-day-old child with MODY with a family background of diabetes. While more data are needed to justify universal screening for diabetes with tests. Practitioners should be vigilant with family history of screening of diabetes. In families two or more generations of diabetes, there should be a low threshold for asymptomatic screening with a serum Hb1Ac.
幼年成熟型糖尿病(MODY)是一种临床上的异质性疾病,其特征是在幼年(小于 25 岁)诊断出非胰岛素依赖型糖尿病,具有常染色体显性遗传和缺乏自身抗体的特点。本病例报告的是一名出生 30 天的婴儿患 MODY 的情况。患者还患有脐疝和胆总管囊肿。我们介绍了一例 30 天大的 MODY 患儿,其家族有糖尿病背景。虽然还需要更多的数据来证明是否有必要通过测试对糖尿病进行普遍筛查。医生应警惕糖尿病家族史筛查。在两代或两代以上患有糖尿病的家族中,使用血清 Hb1Ac 进行无症状筛查的门槛应较低。
{"title":"The first case report on maturity-onset diabetes of young-11 from West Bengal, India","authors":"Manojit Sarkar","doi":"10.3126/ajms.v15i7.66031","DOIUrl":"https://doi.org/10.3126/ajms.v15i7.66031","url":null,"abstract":"Maturity-onset diabetes of young (MODY) is a clinically group of heterogeneous disorder characterized by non-insulin-dependent diabetes diagnosed at a young age (<25 years) with autosomal dominant transmission and lack of autoantibodies. This case report is on MODY in a 30-day-old baby. The patient also has an umbilical hernia and choledochal cyst. We present an instance of 30-day-old child with MODY with a family background of diabetes. While more data are needed to justify universal screening for diabetes with tests. Practitioners should be vigilant with family history of screening of diabetes. In families two or more generations of diabetes, there should be a low threshold for asymptomatic screening with a serum Hb1Ac.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141704396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and socioeconomic pattern of infective dermatoses in pediatric population at a tertiary care center of Northeast India 印度东北部一家三级医疗中心儿科感染性皮肤病的临床和社会经济模式
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.65381
Sagarika Gogoi, Swapan Majumder, Naba Pallab Chetia, Binita Singha
Background: Cutaneous disorders are one of the most important components of any health-care system, especially which including children. Infective dermatoses are the most common skin diseases in children. The pattern of dermatoses in children varies from one country to another and within the same country from one state to another due to various climatic, cultural, and socioeconomic factors.Aims and Objectives: The aims and objectives are to study the clinical and socioeconomic profile of cutaneous infections and infestations among children. Materials and Methods: All children up to 12 years presenting with cutaneous infections and infestations were taken as study participants. A detailed history of the disease, socioeconomic status, and housing condition was taken from the patients as well as from the parents. Local, general, and systemic examinations were carried out on all the children and their examination findings were recorded in a standard pro forma for analysis and interpretation of data.Results: A total number of 1932 were children aged 0–12 years patients attended the Dermatology Outpatient Department during the study period of which 665 (34%) presented with infective dermatoses. 61.20% of patients belonged to school-aged children (5–12 years) 76.7% had a family with 4–6 members. 67.67% were from the rural areas, and 77.4% belonged to the lower class. Scabies was the leading offender (29.92%) among infective dermatoses followed by Impetigo contagiosa (20.45%).Conclusion: There is an increased incidence of cutaneous infections and infestations with increasing age among children. The incidence is associated with housing conditions, family size, socioeconomic strata, and seasonal. Most of these conditions are common and controllable with easy preventive and curative measures.
背景:皮肤疾病是任何医疗保健系统中最重要的组成部分之一,尤其是包括儿童在内的医疗保健系统。感染性皮肤病是儿童最常见的皮肤病。由于气候、文化和社会经济等因素的影响,儿童皮肤病的发病模式因国家而异,在同一国家的不同州也不尽相同:目的和目标:研究儿童皮肤感染和侵袭的临床和社会经济概况。材料和方法:所有 12 岁以下患有皮肤感染和侵袭的儿童均为研究对象。向患者和家长详细询问病史、社会经济状况和住房条件。对所有儿童进行了局部、全身和系统检查,并将检查结果记录在标准表格中,以便对数据进行分析和解释:研究期间,共有 1932 名 0-12 岁儿童在皮肤科门诊部就诊,其中 665 人(34%)患有感染性皮肤病。61.20%的患者属于学龄儿童(5-12 岁),76.7%的患者家庭有 4-6 名成员。67.67%的患者来自农村地区,77.4%属于下层阶级。疥疮是感染性皮肤病的罪魁祸首(29.92%),其次是传染性荨麻疹(20.45%):结论:随着年龄的增长,儿童皮肤感染和感染的发病率也在增加。发病率与居住条件、家庭规模、社会经济阶层和季节有关。这些疾病中的大多数都很常见,并可通过简单的预防和治疗措施加以控制。
{"title":"Clinical and socioeconomic pattern of infective dermatoses in pediatric population at a tertiary care center of Northeast India","authors":"Sagarika Gogoi, Swapan Majumder, Naba Pallab Chetia, Binita Singha","doi":"10.3126/ajms.v15i7.65381","DOIUrl":"https://doi.org/10.3126/ajms.v15i7.65381","url":null,"abstract":"Background: Cutaneous disorders are one of the most important components of any health-care system, especially which including children. Infective dermatoses are the most common skin diseases in children. The pattern of dermatoses in children varies from one country to another and within the same country from one state to another due to various climatic, cultural, and socioeconomic factors.\u0000Aims and Objectives: The aims and objectives are to study the clinical and socioeconomic profile of cutaneous infections and infestations among children.\u0000 Materials and Methods: All children up to 12 years presenting with cutaneous infections and infestations were taken as study participants. A detailed history of the disease, socioeconomic status, and housing condition was taken from the patients as well as from the parents. Local, general, and systemic examinations were carried out on all the children and their examination findings were recorded in a standard pro forma for analysis and interpretation of data.\u0000Results: A total number of 1932 were children aged 0–12 years patients attended the Dermatology Outpatient Department during the study period of which 665 (34%) presented with infective dermatoses. 61.20% of patients belonged to school-aged children (5–12 years) 76.7% had a family with 4–6 members. 67.67% were from the rural areas, and 77.4% belonged to the lower class. Scabies was the leading offender (29.92%) among infective dermatoses followed by Impetigo contagiosa (20.45%).\u0000Conclusion: There is an increased incidence of cutaneous infections and infestations with increasing age among children. The incidence is associated with housing conditions, family size, socioeconomic strata, and seasonal. Most of these conditions are common and controllable with easy preventive and curative measures.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demographics and ultrasonography findings of mastalgia in a tier 2 city of India 印度二级城市乳腺增生症的人口统计学和超声波检查结果
Pub Date : 2024-07-01 DOI: 10.3126/ajms.v15i7.64653
Shivangi Tomar, Rekha Agrawal, Harshit Shrivastava, Akhilendra Singh Parihar
Background: Breast pain is the second most common breast symptom (after breast lump) for which women seeks medical attention. Breast pain can affect daily life, including sleeping, or physical, social, and work-school life. Mastalgia is one of the common causes for women in tier 2 city visiting health care facility but there are only few studies which focus on demographic findings and ultrasonographic findings in mastalgia.Aims and Objectives: The objective of this study was to study demographics of breast pain in a tier 2 city and ultrasound evaluation of mastalgia.Materials and Methods: In this prospective study, 143 patients presenting with mastalgia irrespective of focality, duration, or cyclical nature were included. In these patients, we studied demographic profile and ultrasonographic findings in mastalgia.Results: About 37% women were in 20–29 years of age group and least number was in 70–79 years of age group. About 86% of women in our study were in reproductive age group. Most patient with mastalgia have associated palpable lump (58%) followed by 43% patients with mastalgia and nipple discharge, only 27% of patients have mastalgia alone whereas 4% women have pain with skin changes. The majority (49%) of mastalgia cases fall under the breast imaging-reporting data system (BI-RADS)-I category while cases in BI-RADS-IV and V category were 2 and 1, respectively.Conclusion: Women in their reproductive age group and in their 3rd decade of life are more prone for mastalgia. Ultrasonography is also helpful in detecting cancers in setups where routine mammography is not possible.
背景:乳房疼痛是妇女就医的第二大常见乳房症状(仅次于乳房肿块)。乳房疼痛会影响日常生活,包括睡眠、身体、社交和工作学习。乳房疼痛是二线城市妇女到医疗机构就诊的常见原因之一,但只有少数研究关注乳房疼痛的人口统计学结果和超声波检查结果:本研究旨在研究二线城市乳房疼痛的人口统计学特征以及乳房疼痛的超声评估:在这项前瞻性研究中,共纳入了 143 名乳腺痛患者,不论其病灶、持续时间或周期性。在这些患者中,我们研究了乳腺增生的人口统计学特征和超声波检查结果:结果:约 37% 的女性年龄在 20-29 岁之间,70-79 岁之间的女性人数最少。在我们的研究中,约 86% 的女性处于育龄期。大多数乳腺增生患者(58%)伴有可触及的肿块,43%的患者伴有乳腺增生和乳头溢液,仅有27%的患者仅有乳腺增生,4%的妇女伴有疼痛和皮肤变化。大多数乳痛症病例(49%)属于乳腺成像报告数据系统(BI-RADS)-I 类,而属于 BI-RADS-IV 和 V 类的病例分别为 2 例和 1 例:结论:处于育龄期和生命第三个十年的女性更容易患乳腺增生。在无法进行常规乳房 X 光检查的情况下,超声波检查也有助于检测癌症。
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Asian Journal of Medical Sciences
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