Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.62350
Arunkumar D, Meghan GS, Shivasharan HN, Neeta PN
Background: Gastrointestinal anastomosis is a regularly carried out surgical technique to set up communication between two distant portions of the intestine since the era of Sushruta. There exist different methods of intestinal anastomosis. The newer techniques are Stapling devices over to conventional hand-sewn method of anastomosis. It is proved that a key to a successful anastomosis is accurate anastomosis of two viable ends of the bowel maintaining good vascularity and less tension. Due to consistency, stapler’s can be used at difficult locations. Aims and Objectives: The objective of present study was to compare the outcome of hand-sewn versus stapler anastomosis in elective gastrointestinal surgeries. Materials and Methods: We conducted a prospective and randomized study including 30 study participants each in stapler’s method and hand-sewn method at surgery outpatient department of Kempegouda Institute of Medical Sciences Hospital and Research Center. Results: Stapling procedure took less days to get restored, less time to return of bowel sounds, shorter duration of hospital stays, and less time to resume for oral feeds compared to hand-sewn method and which were statistically significant (P<0.05). Complications such as anastomotic leaks accounted for 3.3% in stapler group and 13.3% in hand-sewn anastomosis, which was not significant statistically. Conclusion: We concluded that time for anastomosis during the procedure, restoration of the gastrointestinal function, oral feeding resumption, and post-operative hospital stay took significantly less time in stapling technique than hand-sewn anastomosis and the staplers looked technically easy compared to hand-sewn method. Complications related to procedure did not show significant differences which helped us to conclude that one can use staplers with similar safety and accuracy as hand suturing method.
{"title":"Efficacy of staplers in comparison with conventional (Hand-Sewn) anastomosis in gastrointestinal surgery – A prospective and randomized study","authors":"Arunkumar D, Meghan GS, Shivasharan HN, Neeta PN","doi":"10.3126/ajms.v15i5.62350","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.62350","url":null,"abstract":"Background: Gastrointestinal anastomosis is a regularly carried out surgical technique to set up communication between two distant portions of the intestine since the era of Sushruta. There exist different methods of intestinal anastomosis. The newer techniques are Stapling devices over to conventional hand-sewn method of anastomosis. It is proved that a key to a successful anastomosis is accurate anastomosis of two viable ends of the bowel maintaining good vascularity and less tension. Due to consistency, stapler’s can be used at difficult locations.\u0000 Aims and Objectives: The objective of present study was to compare the outcome of hand-sewn versus stapler anastomosis in elective gastrointestinal surgeries.\u0000Materials and Methods: We conducted a prospective and randomized study including 30 study participants each in stapler’s method and hand-sewn method at surgery outpatient department of Kempegouda Institute of Medical Sciences Hospital and Research Center.\u0000Results: Stapling procedure took less days to get restored, less time to return of bowel sounds, shorter duration of hospital stays, and less time to resume for oral feeds compared to hand-sewn method and which were statistically significant (P<0.05). Complications such as anastomotic leaks accounted for 3.3% in stapler group and 13.3% in hand-sewn anastomosis, which was not significant statistically.\u0000Conclusion: We concluded that time for anastomosis during the procedure, restoration of the gastrointestinal function, oral feeding resumption, and post-operative hospital stay took significantly less time in stapling technique than hand-sewn anastomosis and the staplers looked technically easy compared to hand-sewn method. Complications related to procedure did not show significant differences which helped us to conclude that one can use staplers with similar safety and accuracy as hand suturing method.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141041543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meningitis is a significant infection of the central nervous system that is followed by inflammation of the meninges, resulting in catastrophic neurologic consequences. The inflammation may be caused by infection with viruses, bacteria, fungi, or other microorganisms and less commonly by certain drugs. Meningitis can be life-threatening because of the inflammation’s proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency. In the present case series, we encompass patient demographics, initial clinical symptoms, physical examinations, laboratory results, cerebrospinal fluid examination findings, treatment side effects, the occurrence of complications, and hospital outcomes. Furthermore, documented were any instances of recurrent cryptococcal meningitis (CM) during follow-up, along with the potential causes of recurrence, the treatment modalities administered, any complications that arose, and the ultimate outcomes. This series reveals CM can manifest alongside HIV co-infection in male patients. Therefore, it is essential to consider the possibility of CM when an immune-compromised patient presents with symptoms such as headaches and other indications of central nervous system involvement. These cases reveal cryptococcosis with HIV-infected patients for rapid and early diagnosis and appropriate treatment of opportunistic infections.
脑膜炎是一种严重的中枢神经系统感染，随后脑膜发炎，导致灾难性的神经系统后果。炎症可能由病毒、细菌、真菌或其他微生物感染引起，也可能由某些药物引起。脑膜炎可危及生命，因为炎症靠近大脑和脊髓；因此，该病症被列为医疗急症。在本病例系列中，我们涵盖了患者的人口统计学特征、最初的临床症状、体格检查、实验室结果、脑脊液检查结果、治疗副作用、并发症的发生以及住院结果。此外，我们还记录了随访期间隐球菌脑膜炎（CM）的复发情况，以及复发的潜在原因、治疗方法、出现的并发症和最终结果。这组病例显示，男性患者在合并感染艾滋病病毒的同时也可能出现隐球菌脑膜炎。因此，当免疫力低下的患者出现头痛等症状和其他中枢神经系统受累的迹象时，必须考虑到 CM 的可能性。这些病例揭示了隐球菌感染与艾滋病病毒感染患者的关系，以便对机会性感染进行快速、早期诊断和适当治疗。
{"title":"Cryptococcal meningitis patients associated with HIV co-infection admitted in tertiary care hospital–A Case Series","authors":"Pushpa Yadav, Reeta Maurya, Alok Kumar Singh, Sunita Yadav, Gargi Tignath Shukla, Manodeep Sen","doi":"10.3126/ajms.v15i5.62021","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.62021","url":null,"abstract":"Meningitis is a significant infection of the central nervous system that is followed by inflammation of the meninges, resulting in catastrophic neurologic consequences. The inflammation may be caused by infection with viruses, bacteria, fungi, or other microorganisms and less commonly by certain drugs. Meningitis can be life-threatening because of the inflammation’s proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency. In the present case series, we encompass patient demographics, initial clinical symptoms, physical examinations, laboratory results, cerebrospinal fluid examination findings, treatment side effects, the occurrence of complications, and hospital outcomes. Furthermore, documented were any instances of recurrent cryptococcal meningitis (CM) during follow-up, along with the potential causes of recurrence, the treatment modalities administered, any complications that arose, and the ultimate outcomes. This series reveals CM can manifest alongside HIV co-infection in male patients. Therefore, it is essential to consider the possibility of CM when an immune-compromised patient presents with symptoms such as headaches and other indications of central nervous system involvement. These cases reveal cryptococcosis with HIV-infected patients for rapid and early diagnosis and appropriate treatment of opportunistic infections.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141032883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.62848
Aniruddha Ghosh, Ambarish Ghosh, SK MaidulIslam, Raghav Oza, Dr. Aniruddha Ghosh
Living with a chronic condition like psoriasis can significantly affect the individual involved. Psoriasis patients have difficulties with their physical, psychological, occupational, and social functioning. These impairments can result in psychiatric morbidity depression and anxiety disorders. This systematic review (SR) assessed the impact of psychological factors in life of psoriasis patients. The literature search comprised Medline through PubMed, Web of Science, the Cochrane Library, Wiley Online Library, and additional sources such as Google Scholar, spanning the period from 2014 to 2023. Thorough examination of the most important electronic databases was conducted. Various study designs, including observational studies, trials, and commentaries, were incorporated to ensure a comprehensive examination of the research topic. The risk of bias was evaluated using established methodology. This SR comprised 13 studies, with the Cochrane Risk of Bias Tool employed to assess biases in randomized trials across five domains. The majority of the studies demonstrated a low risk (57.69%), indicating their reliability while those categorized as unclear (37.17%) exhibited some ambiguity without compromising the validity of results. Studies categorized as high risk (5.12%) suggested significant bias and potential errors. The findings indicate an association between psoriasis and various psychological factors, including depression, anxiety, suicidal ideation, impaired emotional functioning, negative body image, and self-perception. The significant impact of depression and anxiety on individuals with psoriasis underscores the need for greater awareness of its psychological aspects. Incorporating psychological interventions into care and management strategies is crucial for addressing this chronic condition and enhancing overall well-being, thus improving quality of life.
银屑病等慢性疾病会对患者造成严重影响。银屑病患者在身体、心理、职业和社会功能方面都会遇到困难。这些障碍可能导致抑郁症和焦虑症等精神疾病。本系统综述（SR）评估了心理因素对银屑病患者生活的影响。文献检索包括 Medline、PubMed、Web of Science、Cochrane 图书馆、Wiley 在线图书馆以及 Google Scholar 等其他来源，时间跨度为 2014 年至 2023 年。对最重要的电子数据库进行了彻底检查。为了确保对研究课题进行全面审查，我们纳入了各种研究设计，包括观察研究、试验和评论。采用既定方法对偏倚风险进行了评估。该SR包括13项研究，采用了Cochrane偏倚风险工具来评估随机试验中五个领域的偏倚。大多数研究的风险较低（57.69%），表明其可靠性较高，而归类为不明确的研究（37.17%）在不影响结果有效性的前提下表现出一定的模糊性。归类为高风险（5.12%）的研究表明存在重大偏差和潜在错误。研究结果表明，银屑病与各种心理因素有关，包括抑郁、焦虑、自杀倾向、情绪功能受损、负面身体形象和自我认知。抑郁和焦虑对银屑病患者的重大影响凸显了提高对银屑病心理问题认识的必要性。在护理和管理策略中纳入心理干预措施，对于治疗这种慢性疾病、提高整体健康水平从而改善生活质量至关重要。
{"title":"Psychological impact on the quality-of-life in patients of psoriasis vulgaris: A systemic review","authors":"Aniruddha Ghosh, Ambarish Ghosh, SK MaidulIslam, Raghav Oza, Dr. Aniruddha Ghosh","doi":"10.3126/ajms.v15i5.62848","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.62848","url":null,"abstract":"Living with a chronic condition like psoriasis can significantly affect the individual involved. Psoriasis patients have difficulties with their physical, psychological, occupational, and social functioning. These impairments can result in psychiatric morbidity depression and anxiety disorders. This systematic review (SR) assessed the impact of psychological factors in life of psoriasis patients. The literature search comprised Medline through PubMed, Web of Science, the Cochrane Library, Wiley Online Library, and additional sources such as Google Scholar, spanning the period from 2014 to 2023. Thorough examination of the most important electronic databases was conducted. Various study designs, including observational studies, trials, and commentaries, were incorporated to ensure a comprehensive examination of the research topic. The risk of bias was evaluated using established methodology. This SR comprised 13 studies, with the Cochrane Risk of Bias Tool employed to assess biases in randomized trials across five domains. The majority of the studies demonstrated a low risk (57.69%), indicating their reliability while those categorized as unclear (37.17%) exhibited some ambiguity without compromising the validity of results. Studies categorized as high risk (5.12%) suggested significant bias and potential errors. The findings indicate an association between psoriasis and various psychological factors, including depression, anxiety, suicidal ideation, impaired emotional functioning, negative body image, and self-perception. The significant impact of depression and anxiety on individuals with psoriasis underscores the need for greater awareness of its psychological aspects. Incorporating psychological interventions into care and management strategies is crucial for addressing this chronic condition and enhancing overall well-being, thus improving quality of life.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"2 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141055417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.62819
Nizam Ud Din Dar, A. Gania, Tajamul Hussain Dhar, Aijaz Mohi, Ud Din Bhat, J. Kashmir
Background: Dissociation is a complex psychopathology. Symptoms of dissociation are seen in different mental disorders. It is defined as a loss of integration between memory, identity, emotion, perception, behavior, and sense of self. Aims and Objectives: The aim of the study was to study sociodemographic variables of dissociative patients and to study psychiatric morbidities and their correlates concerning dissociative semeiology. Materials and Methods: This study was conducted from June to September 2023, where 51 persons were enrolled, who visited our patient department. Ethical clearance and consent were taken for the study. All the patients were diagnosed by a consultant psychiatrist according to the International Classification of Diseases-10 criteria. Sociodemographic profile pro forma, BG Prasad scale, and Dissociation Experience Scale-II were administered. Result: The majority of patients were from the 19 to 23-year-old age group, unmarried females residing in rural areas living in nuclear families having middle economic status who achieved middle education. The majority of patients had psychogenic non-epileptic seizures as a dominant symptom with school-related issues as a precipitant factor with the majority having a major depressive disorder. The correlation was significant at the 0.005 level. A correlation of P<0.005 for anxiety, depression, obsessive-compulsive disorder, and adjustment disorder with dissociative symptoms was seen. A P<0.005 was seen for sex, education, economic status, and occupation to that of dissociative symptoms. Conclusion: Dissociation symptoms have multiple comorbid psychiatric disorders comorbidly present. Precipitating factors need to be taken care of. Intervention should be multipronged. Psychological interventions may help manage different subconscious conflicts.
{"title":"Correlative analysis of dissociative disorder among Kashmiri population","authors":"Nizam Ud Din Dar, A. Gania, Tajamul Hussain Dhar, Aijaz Mohi, Ud Din Bhat, J. Kashmir","doi":"10.3126/ajms.v15i5.62819","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.62819","url":null,"abstract":"Background: Dissociation is a complex psychopathology. Symptoms of dissociation are seen in different mental disorders. It is defined as a loss of integration between memory, identity, emotion, perception, behavior, and sense of self.\u0000Aims and Objectives: The aim of the study was to study sociodemographic variables of dissociative patients and to study psychiatric morbidities and their correlates concerning dissociative semeiology.\u0000Materials and Methods: This study was conducted from June to September 2023, where 51 persons were enrolled, who visited our patient department. Ethical clearance and consent were taken for the study. All the patients were diagnosed by a consultant psychiatrist according to the International Classification of Diseases-10 criteria. Sociodemographic profile pro forma, BG Prasad scale, and Dissociation Experience Scale-II were administered.\u0000 Result: The majority of patients were from the 19 to 23-year-old age group, unmarried females residing in rural areas living in nuclear families having middle economic status who achieved middle education. The majority of patients had psychogenic non-epileptic seizures as a dominant symptom with school-related issues as a precipitant factor with the majority having a major depressive disorder. The correlation was significant at the 0.005 level. A correlation of P<0.005 for anxiety, depression, obsessive-compulsive disorder, and adjustment disorder with dissociative symptoms was seen. A P<0.005 was seen for sex, education, economic status, and occupation to that of dissociative symptoms.\u0000Conclusion: Dissociation symptoms have multiple comorbid psychiatric disorders comorbidly present. Precipitating factors need to be taken care of. Intervention should be multipronged. Psychological interventions may help manage different subconscious conflicts.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"47 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141030452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.51682
Sonali Sain, I. Dey, Nabanita Chakraborty
Background: Cervical cancer is a major public health problem, especially worldwide. Lack of awareness about the risk factors, signs and symptoms, and danger signs has led to a rise in the prevalence of the disease in countries like India. Aims and Objectives: The aim of the study was to assess the awareness of cervical cancer and its risk factors among the adult female population residing in the urban slum of Kolkata Municipal Corporation area and their attitude toward the disease. Materials and Methods: A cross-sectional study was conducted among 720 adult female residents of the field practice area of the urban health training center of NRS Medical College using a predesigned pretested questionnaire. Results: In the current study, 58.3% of subjects were married at <18 years of age and 38.3% with >2 children. A significant association was found among inter-menstrual bleeding and persistent low back pain with a family history of cancer, persistent vaginal discharge, and postmenopausal bleeding with education, dyspareunia showed significant association with age, education, and family type, heavy menstruation with religion. Furthermore, the association between postcoital bleeding with education and blood in the urine or stool with marital status was found to be significant. A significant association was found between confidences about noticing a symptom with marital status (P<0.05). Conclusion: Unsatisfactory knowledge about cervical cancer among adult women in an urban slum poses the risk of the disease. Awareness of risk factors of cervical cancer, along with early diagnosis and treatment, can decline the burden of the disease.
{"title":"An observational study to assess awareness of cervical cancer among the adult women of field practice area of urban health training center in Kolkata","authors":"Sonali Sain, I. Dey, Nabanita Chakraborty","doi":"10.3126/ajms.v15i5.51682","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.51682","url":null,"abstract":"Background: Cervical cancer is a major public health problem, especially worldwide. Lack of awareness about the risk factors, signs and symptoms, and danger signs has led to a rise in the prevalence of the disease in countries like India.\u0000Aims and Objectives: The aim of the study was to assess the awareness of cervical cancer and its risk factors among the adult female population residing in the urban slum of Kolkata Municipal Corporation area and their attitude toward the disease.\u0000Materials and Methods: A cross-sectional study was conducted among 720 adult female residents of the field practice area of the urban health training center of NRS Medical College using a predesigned pretested questionnaire.\u0000Results: In the current study, 58.3% of subjects were married at <18 years of age and 38.3% with >2 children. A significant association was found among inter-menstrual bleeding and persistent low back pain with a family history of cancer, persistent vaginal discharge, and postmenopausal bleeding with education, dyspareunia showed significant association with age, education, and family type, heavy menstruation with religion. Furthermore, the association between postcoital bleeding with education and blood in the urine or stool with marital status was found to be significant. A significant association was found between confidences about noticing a symptom with marital status (P<0.05).\u0000Conclusion: Unsatisfactory knowledge about cervical cancer among adult women in an urban slum poses the risk of the disease. Awareness of risk factors of cervical cancer, along with early diagnosis and treatment, can decline the burden of the disease.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"30 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141046336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.62145
Dr. Akhilendra Singh Parihar, Dr. Vaishali Jain, Dr. Avyact Agrawal, Dr. Shivangi Tomar
Background: Severe acute malnutrition (SAM) is a grave form of undernutrition that has been recognized as a medical and social disorder. Various factors contribute to the development of SAM, but the impact of maternal education on the nutritional status and development of the child is of paramount importance since focused interventions in this aspect can yield promising results. Aims and Objectives: The aims and objectives of the study are to assess the impact of maternal education on the development of children with SAM. Materials and Methods: A total of 125 SAM children in the age group 12–30 months were enrolled in this prospective observational study from among those admitted to the nutritional rehabilitation center of a tertiary care center in central India. The developmental status of SAM children was assessed using the Developmental Assessment Scale of Indian Infants. The association of maternal education with the development of SAM children was analyzed. Results: Overall developmental delay was observed in 44.8% of SAM children, whereas motor and mental development delay was noted in 45.6% and 44% of SAM children. The maternal education level was significantly associated with the overall development of the SAM child. (P=0.043 for motor development, P=0.017 for mental development, P=0.023 for motor developmental delay). Conclusion: Maternal education plays a key role in improving the developmental status of SAM children, who are more prone to developmental delays across various domains. Efforts toward enhancing maternal education, especially knowledge regarding child nutrition and development, can reduce the incidence and improve the management of SAM in children.
背景：严重急性营养不良（SAM）是一种严重的营养不良形式，已被视为一种医学和社会疾病。导致严重急性营养不良的因素多种多样，但孕产妇教育对儿童营养状况和发育的影响至关重要，因为在这方面进行有针对性的干预会产生良好的效果：本研究的目的和目标是评估母亲教育对 SAM 儿童发育的影响。材料与方法：这项前瞻性观察研究从印度中部一家三级护理中心的营养康复中心收治的 12-30 个月大的 SAM 儿童中选取了 125 名儿童。研究人员使用印度婴儿发育评估量表（Developmental Assessment Scale of Indian Infants）对SAM儿童的发育状况进行了评估。研究还分析了母亲教育程度与萨姆儿童发育的关系：结果：44.8%的SAM儿童出现整体发育迟缓，45.6%的SAM儿童出现运动和智力发育迟缓，44%的SAM儿童出现运动和智力发育迟缓。母亲的受教育程度与 SAM 儿童的整体发育有明显关系。(运动发育迟缓的 P=0.043，智力发育迟缓的 P=0.017，运动发育迟缓的 P=0.023）。结论母亲教育对改善 SAM 儿童的发育状况起着关键作用，因为 SAM 儿童更容易在各个领域出现发育迟缓。努力加强孕产妇教育，特别是有关儿童营养和发育的知识，可以降低 SAM 儿童的发病率并改善对他们的管理。
{"title":"Impact of maternal education on the development of severe acute malnourished children","authors":"Dr. Akhilendra Singh Parihar, Dr. Vaishali Jain, Dr. Avyact Agrawal, Dr. Shivangi Tomar","doi":"10.3126/ajms.v15i5.62145","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.62145","url":null,"abstract":"Background: Severe acute malnutrition (SAM) is a grave form of undernutrition that has been recognized as a medical and social disorder. Various factors contribute to the development of SAM, but the impact of maternal education on the nutritional status and development of the child is of paramount importance since focused interventions in this aspect can yield promising results.\u0000Aims and Objectives: The aims and objectives of the study are to assess the impact of maternal education on the development of children with SAM.\u0000 Materials and Methods: A total of 125 SAM children in the age group 12–30 months were enrolled in this prospective observational study from among those admitted to the nutritional rehabilitation center of a tertiary care center in central India. The developmental status of SAM children was assessed using the Developmental Assessment Scale of Indian Infants. The association of maternal education with the development of SAM children was analyzed.\u0000Results: Overall developmental delay was observed in 44.8% of SAM children, whereas motor and mental development delay was noted in 45.6% and 44% of SAM children. The maternal education level was significantly associated with the overall development of the SAM child. (P=0.043 for motor development, P=0.017 for mental development, P=0.023 for motor developmental delay).\u0000 Conclusion: Maternal education plays a key role in improving the developmental status of SAM children, who are more prone to developmental delays across various domains. Efforts toward enhancing maternal education, especially knowledge regarding child nutrition and development, can reduce the incidence and improve the management of SAM in children.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"49 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.61997
Debolina Pramanik, Debadatta Chakrabarty, Soumitra Mondal, Atanu Roy
Background: HIV infection is a serious lifelong health risk, leading to increased illness and death. In children, adhering to antiretroviral therapy (ART) is crucial to reduce these harmful effects. Yet, due to the challenges of pediatric patients and the social issues related to HIV, sticking to ART can be difficult in this group. Aims and Objectives: The study was conducted to evaluate the adherence of pediatric patients to their daily ART dosages. We also tried to understand the causes that led to the failure to follow the scheduled dosages and evaluate how these factors affected our study population. Materials and Methods: We examined the adherence to ART in 49 patients, aged 2–15, who had been on ART for at least 12 months. They visited the ART center at Medical College and Hospital, Kolkata, between August 01 and September 30, 2022. Ethical clearance was granted by the Institution’s Ethics Committee. The participants were chosen through systematic random sampling. We collected data through interviews and chart reviews and analyzed it using SPSS version 19. Results: Out of the 49 participants, 34 (69.38%) adhered to ART in the preceding month. For the non-adherent patients (n=15), the main reasons included conflicting ART dosage timing with school hours and children falling asleep at dosing time. Most (53.1%) were in the 5–10 age groups, with 93.88% in WHO Stage 1 of the disease and 6.12% in Stage II. In 77.6% of cases, mothers were the primary caregivers, and 79.6% of caregivers were HIV positive. Many children (71.43%) were unaware of their disease. Out of the 31 children whose disease status was known to others, grandparents of 23 and siblings of 12 were aware. Six of these children faced stigma from relatives and neighbors. ART adherence was significantly associated (P<0.05) with the caregiver’s occupation (P=0.006), the child’s age when starting ART (P=0.001), parents’ AIDS-related deaths (P=0.003), and travel time to the ART center from home (P<0.02). Conclusion: Although most children adhered to their ART regimen, there is room for improvement. Caregivers, especially for younger children, play a crucial role. Empathetic education for caregivers and children, tailored to their age, along with regular adherence checks, can enhance medication adherence significantly.
{"title":"A cross-sectional study on adherence to antiretroviral therapy among HIV-infected pediatric patients attending medical college and hospital, Kolkata","authors":"Debolina Pramanik, Debadatta Chakrabarty, Soumitra Mondal, Atanu Roy","doi":"10.3126/ajms.v15i5.61997","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.61997","url":null,"abstract":"Background: HIV infection is a serious lifelong health risk, leading to increased illness and death. In children, adhering to antiretroviral therapy (ART) is crucial to reduce these harmful effects. Yet, due to the challenges of pediatric patients and the social issues related to HIV, sticking to ART can be difficult in this group.\u0000Aims and Objectives: The study was conducted to evaluate the adherence of pediatric patients to their daily ART dosages. We also tried to understand the causes that led to the failure to follow the scheduled dosages and evaluate how these factors affected our study population.\u0000Materials and Methods: We examined the adherence to ART in 49 patients, aged 2–15, who had been on ART for at least 12 months. They visited the ART center at Medical College and Hospital, Kolkata, between August 01 and September 30, 2022. Ethical clearance was granted by the Institution’s Ethics Committee. The participants were chosen through systematic random sampling. We collected data through interviews and chart reviews and analyzed it using SPSS version 19.\u0000Results: Out of the 49 participants, 34 (69.38%) adhered to ART in the preceding month. For the non-adherent patients (n=15), the main reasons included conflicting ART dosage timing with school hours and children falling asleep at dosing time. Most (53.1%) were in the 5–10 age groups, with 93.88% in WHO Stage 1 of the disease and 6.12% in Stage II. In 77.6% of cases, mothers were the primary caregivers, and 79.6% of caregivers were HIV positive. Many children (71.43%) were unaware of their disease. Out of the 31 children whose disease status was known to others, grandparents of 23 and siblings of 12 were aware. Six of these children faced stigma from relatives and neighbors. ART adherence was significantly associated (P<0.05) with the caregiver’s occupation (P=0.006), the child’s age when starting ART (P=0.001), parents’ AIDS-related deaths (P=0.003), and travel time to the ART center from home (P<0.02).\u0000Conclusion: Although most children adhered to their ART regimen, there is room for improvement. Caregivers, especially for younger children, play a crucial role. Empathetic education for caregivers and children, tailored to their age, along with regular adherence checks, can enhance medication adherence significantly.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"47 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141041023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.63669
Anu Hansa, Zulfiqar Ali, Iqra Nazir, Altaf Mir, Zoya Sehar, Mir Mohsin, Shahid Ahmad Mir, I. Naqash
Background: The occurrence of delirium in patients who undergo elective surgeries is a common occurrence. Multiple studies have assessed the effect of different drugs in various elective procedures to decrease the prevalence of postoperative delirium. The effect of melatonin to decrease the prevalence of delirium and duration of neurosurgical intensive care unit (NSICU) stay in patients undergoing neurosurgery has not been studied previously. The current study aimed to assess the same. Aims and Objectives: To assess the effect of preoperative and postoperative melatonin administration on the prevalence of delirium in patients undergoing elective ventilation in NSICU and to assess the effect of preoperative and postoperative melatonin administration on the duration of stay in NSICU. Methods and Methods: In this prospective observational study, 60 patients undergoing various neurosurgical procedures and admitted to NSICU were included. The patients were divided into two groups: one group received a placebo (Group P- tablet Sugarfree containing Aspartame) and another group received a tablet of melatonin 3 mg (Group M) in the preoperative and postoperative period. The effect of melatonin on the prevalence of delirium and duration of NSICU stay in these two groups was observed. Results: A decreasing trend of delirium was noted in both groups (Group M and Group P) with no statistical significance. A decreased prevalence of delirium was observed in patients of group M (33.3%) at the end of 12 h post-extubation compared to Group P (43.3%). The mean duration of stay for the patients in NSICU in Groups M and P were 2.7 and 3.2 days, with the range (1–14 Days) in Group M and Group P (1–20 days), respectively. Conclusion: Although there was a decreased prevalence of delirium and a decrease in the mean duration of the intensive care unit stay in patients who received oral melatonin, these beneficial effects did not show any statistical significance once compared with the control group.
{"title":"Effects of administration of melatonin on prevalence of delirium and duration of stay in patients admitted to neurosurgical intensive care unit – A prospective study","authors":"Anu Hansa, Zulfiqar Ali, Iqra Nazir, Altaf Mir, Zoya Sehar, Mir Mohsin, Shahid Ahmad Mir, I. Naqash","doi":"10.3126/ajms.v15i5.63669","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.63669","url":null,"abstract":"Background: The occurrence of delirium in patients who undergo elective surgeries is a common occurrence. Multiple studies have assessed the effect of different drugs in various elective procedures to decrease the prevalence of postoperative delirium. The effect of melatonin to decrease the prevalence of delirium and duration of neurosurgical intensive care unit (NSICU) stay in patients undergoing neurosurgery has not been studied previously. The current study aimed to assess the same.\u0000Aims and Objectives: To assess the effect of preoperative and postoperative melatonin administration on the prevalence of delirium in patients undergoing elective ventilation in NSICU and to assess the effect of preoperative and postoperative melatonin administration on the duration of stay in NSICU.\u0000Methods and Methods: In this prospective observational study, 60 patients undergoing various neurosurgical procedures and admitted to NSICU were included. The patients were divided into two groups: one group received a placebo (Group P- tablet Sugarfree containing Aspartame) and another group received a tablet of melatonin 3 mg (Group M) in the preoperative and postoperative period. The effect of melatonin on the prevalence of delirium and duration of NSICU stay in these two groups was observed.\u0000 Results: A decreasing trend of delirium was noted in both groups (Group M and Group P) with no statistical significance. A decreased prevalence of delirium was observed in patients of group M (33.3%) at the end of 12 h post-extubation compared to Group P (43.3%). The mean duration of stay for the patients in NSICU in Groups M and P were 2.7 and 3.2 days, with the range (1–14 Days) in Group M and Group P (1–20 days), respectively.\u0000 Conclusion: Although there was a decreased prevalence of delirium and a decrease in the mean duration of the intensive care unit stay in patients who received oral melatonin, these beneficial effects did not show any statistical significance once compared with the control group.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"31 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141041548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.63477
Swastika Debbarma, Aniruddha Ghosh
Background: Changes in skin, hair, and nails may be initial manifestations of an underlying thyroid hormone deficiency. Symptomatic treatment of cutaneous manifestations without treatment of underlying hypothyroidism contributes to long-term morbidity in patients. Aims and Objectives: The aim of the study was to study the cutaneous manifestations and demographic profile of patients with hypothyroidism. Materials and Methods: We conducted a hospital-based cross-sectional study of 200 patients presenting with cutaneous changes in primary hypothyroidism for a period of 18 months. A detailed history, clinical examination, and relevant investigations were performed. Results: Out of 200 patients, cutaneous manifestations were more prevalent in the age group between 30 and 49 years. The ratio of male to female was 1.0:6.4. A family history of hypothyroidism was present in 34.5% of patients. The most common cutaneous features were alteration in skin texture (53.0%), dry skin (48.5%), generalized pruritus (42.5%), urticaria (17%), followed by pigmentation of the skin (34.5%), out of which vitiligo was 9.0%, melasma was 5.5%, and others were 20.0%. Other changes include xerosis (32.5%), eczematous disorder (13%), acquired palmoplantar keratoderma (11.5%), and brittle nails (3.5%). 39.5% had hair changes, out of which diffuse hair loss was 17.5%, coarse hair wa s 12%, alopecia areata was 4.5%, and lateral loss of eyebrows was 4.5%. Changes in the oral cavity and mucous membrane were present in 3.0% of the patients, which included lip vitiligo (1.5%), oral lichen planus (1%), and oral candidiasis (0.5%). Menstrual abnormalities were present in 50.84% of females. The percentage of hypothyroid patients who complained of easy fatigability, facial puffiness, cold intolerance, weight gain, constipation, neck swelling, hoarseness of voice, increased sleeping pattern, and non-pitting edema of feet were 38.5%, 36.5%, 26.0%, 23.5%, 17.0%, 9%, 8%, 7.5%, and 6.5%, respectively. Conclusion: Based on our study, it can be concluded that the presence of certain skin conditions, such as alteration in skin texture, dry skin, generalized pruritus, urticaria, skin pigmentation, and diffuse hair loss, may indicate the possibility of hypothyroidism. These cutaneous manifestations may occur earlier than the diagnosis of hypothyroidism through biochemical testing. Therefore, it is important to consider the possibility of hypothyroidism when examining patients with these skin conditions.
{"title":"Cutaneous manifestations of hypothyroidism: An observational study in a tertiary care center of Eastern India","authors":"Swastika Debbarma, Aniruddha Ghosh","doi":"10.3126/ajms.v15i5.63477","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.63477","url":null,"abstract":"Background: Changes in skin, hair, and nails may be initial manifestations of an underlying thyroid hormone deficiency. Symptomatic treatment of cutaneous manifestations without treatment of underlying hypothyroidism contributes to long-term morbidity in patients.\u0000 Aims and Objectives: The aim of the study was to study the cutaneous manifestations and demographic profile of patients with hypothyroidism.\u0000 Materials and Methods: We conducted a hospital-based cross-sectional study of 200 patients presenting with cutaneous changes in primary hypothyroidism for a period of 18 months. A detailed history, clinical examination, and relevant investigations were performed.\u0000Results: Out of 200 patients, cutaneous manifestations were more prevalent in the age group between 30 and 49 years. The ratio of male to female was 1.0:6.4. A family history of hypothyroidism was present in 34.5% of patients. The most common cutaneous features were alteration in skin texture (53.0%), dry skin (48.5%), generalized pruritus (42.5%), urticaria (17%), followed by pigmentation of the skin (34.5%), out of which vitiligo was 9.0%, melasma was 5.5%, and others were 20.0%. Other changes include xerosis (32.5%), eczematous disorder (13%), acquired palmoplantar keratoderma (11.5%), and brittle nails (3.5%). 39.5% had hair changes, out of which diffuse hair loss was 17.5%, coarse hair wa s 12%, alopecia areata was 4.5%, and lateral loss of eyebrows was 4.5%. Changes in the oral cavity and mucous membrane were present in 3.0% of the patients, which included lip vitiligo (1.5%), oral lichen planus (1%), and oral candidiasis (0.5%). Menstrual abnormalities were present in 50.84% of females. The percentage of hypothyroid patients who complained of easy fatigability, facial puffiness, cold intolerance, weight gain, constipation, neck swelling, hoarseness of voice, increased sleeping pattern, and non-pitting edema of feet were 38.5%, 36.5%, 26.0%, 23.5%, 17.0%, 9%, 8%, 7.5%, and 6.5%, respectively.\u0000Conclusion: Based on our study, it can be concluded that the presence of certain skin conditions, such as alteration in skin texture, dry skin, generalized pruritus, urticaria, skin pigmentation, and diffuse hair loss, may indicate the possibility of hypothyroidism. These cutaneous manifestations may occur earlier than the diagnosis of hypothyroidism through biochemical testing. Therefore, it is important to consider the possibility of hypothyroidism when examining patients with these skin conditions.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"38 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141032765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.3126/ajms.v15i5.62896
S. K. Sutrakar, Sakshi Chaurasia, Parul Singh Rajpoot, Priyanka Agrawal, Lokesh Tripathi, Uday Raj Singh, Sadhana Yadav, Junior Resident
Background: Blood transfusions play a pivotal role in medical care, saving millions of lives annually. The timely provision of safe blood is critical in various clinical scenarios, necessitating a careful balance between supply and demand. Despite advanced blood banking facilities globally, challenges persist in ensuring appropriate blood component utilization, prompting a need for clinical audits and optimization strategies. Aims and Objectives: This study aims to analyze the patterns of blood product utilization in a tertiary care hospital in Madhya Pradesh over 1 year, focusing on transfusion requests, cross-match-to-transfusion (C/T) ratios, transfusion indices (TIs), and indications for transfusions. Materials and Methods: A retrospective study was conducted at Shyam Shah Medical College from January 01, 2023, to December 31, 2023. Data from transfusion and cross-match requests in various departments were collected. C/T ratios, TI, and non-usage probability were computed to assess blood utilization efficiency. Results: Out of 16,682 cross-matched units, 71.93% were transfused. The overall C/T ratio was 1.39. The department of medicine demonstrated the most efficient blood usage with a C/T ratio of 1.16. Obstetrics and gynecology had the highest TI (1.06), while surgery had the lowest (0.71). Indications for transfusion included anemia (29.9%), pre-operative (17.2%), intraoperative (21.8%), and post-operative (31.1%). Conclusion: This study provides valuable insights into blood utilization patterns, offering a foundation for refining transfusion practices and enhancing the efficiency of blood management in the studied tertiary care hospital.
{"title":"Unveiling transfusions: Analyzing blood product utilization patterns in a leading tertiary care center in Madhya Pradesh, India","authors":"S. K. Sutrakar, Sakshi Chaurasia, Parul Singh Rajpoot, Priyanka Agrawal, Lokesh Tripathi, Uday Raj Singh, Sadhana Yadav, Junior Resident","doi":"10.3126/ajms.v15i5.62896","DOIUrl":"https://doi.org/10.3126/ajms.v15i5.62896","url":null,"abstract":"Background: Blood transfusions play a pivotal role in medical care, saving millions of lives annually. The timely provision of safe blood is critical in various clinical scenarios, necessitating a careful balance between supply and demand. Despite advanced blood banking facilities globally, challenges persist in ensuring appropriate blood component utilization, prompting a need for clinical audits and optimization strategies.\u0000Aims and Objectives: This study aims to analyze the patterns of blood product utilization in a tertiary care hospital in Madhya Pradesh over 1 year, focusing on transfusion requests, cross-match-to-transfusion (C/T) ratios, transfusion indices (TIs), and indications for transfusions.\u0000Materials and Methods: A retrospective study was conducted at Shyam Shah Medical College from January 01, 2023, to December 31, 2023. Data from transfusion and cross-match requests in various departments were collected. C/T ratios, TI, and non-usage probability were computed to assess blood utilization efficiency.\u0000Results: Out of 16,682 cross-matched units, 71.93% were transfused. The overall C/T ratio was 1.39. The department of medicine demonstrated the most efficient blood usage with a C/T ratio of 1.16. Obstetrics and gynecology had the highest TI (1.06), while surgery had the lowest (0.71). Indications for transfusion included anemia (29.9%), pre-operative (17.2%), intraoperative (21.8%), and post-operative (31.1%).\u0000Conclusion: This study provides valuable insights into blood utilization patterns, offering a foundation for refining transfusion practices and enhancing the efficiency of blood management in the studied tertiary care hospital.","PeriodicalId":8522,"journal":{"name":"Asian Journal of Medical Sciences","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141026268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：