Asia-Pacific Journal of Oncology Nursing最新文献_第2页

Correlation between cancer cachexia and psychosocial impact in older patients with advanced lung cancer undergoing chemotherapy

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2025-01-23 DOI: 10.1016/j.apjon.2025.100658

Rika Sato , Tateaki Naito , Haruyasu Murakami , Shota Omori , Haruki Kobayashi , Akira Ono , Nobuaki Mamesaya , Kazushige Wakuda , Ryo Ko , Hirotsugu Kenmotsu , Sakiko Aso , Miho Hasaba , Keita Mori , Toshiaki Takahashi , Naoko Hayashi

Objective

This study aimed to evaluate the association of cancer cachexia with psychosocial impact, nutrition impact symptoms (NIS), and geriatric assessment in older patients newly diagnosed with advanced lung cancer undergoing chemotherapy.

Methods

Older patients with advanced lung cancer scheduled to receive first-line chemotherapy between August 2021 and February 2022 were enrolled. Cachexia was diagnosed according to the International Consensus. NIS and psychosocial impacts were assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaires (EORTC QLQ) C30, CAX24, and the Eating-Related Distress Questionnaire (ERD). Non-parametric tests evaluated the association between cachexia and its impacts. Patients with cachexia who consented to be interviewed were asked about their experiences with diet and weight changes. Three authors reviewed the interview data to ensure the analysis's veracity.

Results

Twenty-one of the 31 participants (68%) had cachexia at baseline. The cachexia group showed significantly greater severity of Food Aversion (P = 0.035), Eating and Weight Loss Worry (P < 0.001), and Loss of Control (P = 0.005) compared to the non-cachexia group. There were no significant differences in the ERD and geriatric assessment (all P > 0.05). The interview revealed that patients with cachexia perceived diet and weight changes early on and tried to manage their symptoms by themselves.

Conclusions

Cancer cachexia showed an association with NIS and psychosocial impacts. Older patients with advanced lung cancer scheduled to receive first-line chemotherapy should undergo a comprehensive assessment of cancer cachexia, including its potential physical and psychological impacts.

Trial registration

The trial registration number was UMIN 000053843.

{"title":"Correlation between cancer cachexia and psychosocial impact in older patients with advanced lung cancer undergoing chemotherapy","authors":"Rika Sato , Tateaki Naito , Haruyasu Murakami , Shota Omori , Haruki Kobayashi , Akira Ono , Nobuaki Mamesaya , Kazushige Wakuda , Ryo Ko , Hirotsugu Kenmotsu , Sakiko Aso , Miho Hasaba , Keita Mori , Toshiaki Takahashi , Naoko Hayashi","doi":"10.1016/j.apjon.2025.100658","DOIUrl":"10.1016/j.apjon.2025.100658","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the association of cancer cachexia with psychosocial impact, nutrition impact symptoms (NIS), and geriatric assessment in older patients newly diagnosed with advanced lung cancer undergoing chemotherapy.</div></div><div><h3>Methods</h3><div>Older patients with advanced lung cancer scheduled to receive first-line chemotherapy between August 2021 and February 2022 were enrolled. Cachexia was diagnosed according to the International Consensus. NIS and psychosocial impacts were assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaires (EORTC QLQ) C30, CAX24, and the Eating-Related Distress Questionnaire (ERD). Non-parametric tests evaluated the association between cachexia and its impacts. Patients with cachexia who consented to be interviewed were asked about their experiences with diet and weight changes. Three authors reviewed the interview data to ensure the analysis's veracity.</div></div><div><h3>Results</h3><div>Twenty-one of the 31 participants (68%) had cachexia at baseline. The cachexia group showed significantly greater severity of Food Aversion (<em>P</em> = 0.035), Eating and Weight Loss Worry (<em>P</em> < 0.001), and Loss of Control (<em>P</em> = 0.005) compared to the non-cachexia group. There were no significant differences in the ERD and geriatric assessment (all <em>P</em> > 0.05). The interview revealed that patients with cachexia perceived diet and weight changes early on and tried to manage their symptoms by themselves.</div></div><div><h3>Conclusions</h3><div>Cancer cachexia showed an association with NIS and psychosocial impacts. Older patients with advanced lung cancer scheduled to receive first-line chemotherapy should undergo a comprehensive assessment of cancer cachexia, including its potential physical and psychological impacts.</div></div><div><h3>Trial registration</h3><div>The trial registration number was UMIN 000053843.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100658"},"PeriodicalIF":2.4,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2025-01-21 DOI: 10.1016/j.apjon.2025.100655

Yingtao Meng , Ruitong Gao , Hailing Yang , Fang Zhang , Meimei Shang , Yuping Liu , Lingjuan Li , Lu Chen , Xia Zhong , Hongmei Lu

Objective

Esophagectomy is a primary curable treatment and a highly challenging procedure for esophageal cancer (EC) survivors. EC survivors experience various unmet needs. This study is aimed to assess unmet needs, health-related quality of life (HRQOL), and psychological distress of postoperative EC survivors.

Methods

A multicenter cross-sectional study was conducted between December 2023 and March 2024 across 28 hospitals in northern China. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Hospital Anxiety and Depression Scale, and Supportive Care Need Survey - Short Form 34 were utilized to assess the HRQOL, anxiety, depression, and unmet needs.

Results

A total of 357 postoperative EC survivors were recruited, with a mean age of 63.42 years. Approximately 14.6% exhibited borderline anxiety, and 17.9% showed borderline depression. Unmet needs were highest in health information and patient care domains. HRQOL was lower in global health, social, and physical functions post-surgery. Fatigue, appetite loss, insomnia, and financial difficulties were common. Dysphagia, dry mouth, reflux, and choking negatively impacted HRQOL. Multivariable regression analysis indicated that anxiety and depression levels were higher, and HRQOL was lower in those one week to six months post-surgery compared to one-week post-surgery.

Conclusions

EC survivors experience significant psychological distress and reduced HRQOL up to six months post-surgery. Dysphagia and unmet needs are prevalent. Compared to immediate post-surgery, EC survivors experienced higher levels of anxiety and depression, and lower level of HRQOL in six months. Future research should focus on developing individualized care strategies to provide optimal support.

{"title":"Health-related quality of life and related factors among esophageal cancer survivors after esophagectomy in the 6-month postoperative period: A multicenter cross-sectional study in north China","authors":"Yingtao Meng , Ruitong Gao , Hailing Yang , Fang Zhang , Meimei Shang , Yuping Liu , Lingjuan Li , Lu Chen , Xia Zhong , Hongmei Lu","doi":"10.1016/j.apjon.2025.100655","DOIUrl":"10.1016/j.apjon.2025.100655","url":null,"abstract":"<div><h3>Objective</h3><div>Esophagectomy is a primary curable treatment and a highly challenging procedure for esophageal cancer (EC) survivors. EC survivors experience various unmet needs. This study is aimed to assess unmet needs, health-related quality of life (HRQOL), and psychological distress of postoperative EC survivors.</div></div><div><h3>Methods</h3><div>A multicenter cross-sectional study was conducted between December 2023 and March 2024 across 28 hospitals in northern China. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Hospital Anxiety and Depression Scale, and Supportive Care Need Survey - Short Form 34 were utilized to assess the HRQOL, anxiety, depression, and unmet needs.</div></div><div><h3>Results</h3><div>A total of 357 postoperative EC survivors were recruited, with a mean age of 63.42 years. Approximately 14.6% exhibited borderline anxiety, and 17.9% showed borderline depression. Unmet needs were highest in health information and patient care domains. HRQOL was lower in global health, social, and physical functions post-surgery. Fatigue, appetite loss, insomnia, and financial difficulties were common. Dysphagia, dry mouth, reflux, and choking negatively impacted HRQOL. Multivariable regression analysis indicated that anxiety and depression levels were higher, and HRQOL was lower in those one week to six months post-surgery compared to one-week post-surgery.</div></div><div><h3>Conclusions</h3><div>EC survivors experience significant psychological distress and reduced HRQOL up to six months post-surgery. Dysphagia and unmet needs are prevalent. Compared to immediate post-surgery, EC survivors experienced higher levels of anxiety and depression, and lower level of HRQOL in six months. Future research should focus on developing individualized care strategies to provide optimal support.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100655"},"PeriodicalIF":2.4,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing cancer-related fatigue: Validation of the Korean version of the cancer fatigue scale among cancer survivors

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2025-01-20 DOI: 10.1016/j.apjon.2025.100657

Haneul Lee , Eun Young Park , Kwang-Hi Park

Objective

This study aimed to validate the Korean version of the Cancer Fatigue Scale (CFS-K) as a reliable tool for assessing cancer-related fatigue (CRF) for cancer survivors.

Methods

A total of 208 cancer survivors who completed active treatment participated in evaluating the reliability, construct validity, and factor structure of the CFS-K through confirmatory factor analysis (CFA). Correlations with the Functional Assessment of Chronic Illness Therapy-Fatigue (FACT-F) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 (EORTC QLQ-C30) scales were analyzed to assess construct validity.

Results

The CFS-K demonstrated strong psychometric properties, with high internal consistency (Cronbach’s α = 0.875) and CFA validated a three-factor structure (physical, cognitive, and affective fatigue) with acceptable model fit indices (normed χ² = 2.62, CFI = 0.899, TLI = 0.878, RMSEA = 0.088, SRMR = 0.069). The standardized factor loadings for all items exceeded 0.5. Construct validity was confirmed through strong correlations with FACT-F (r = 0.43–0.73) and significant correlations with EORTC QLQ-C30 subscales. Cancer survivors reported significantly higher fatigue levels across all subscales than controls.

Conclusions

The CFS-K is a reliable and valid tool for assessing multidimensional CRF in cancer survivors.

{"title":"Assessing cancer-related fatigue: Validation of the Korean version of the cancer fatigue scale among cancer survivors","authors":"Haneul Lee , Eun Young Park , Kwang-Hi Park","doi":"10.1016/j.apjon.2025.100657","DOIUrl":"10.1016/j.apjon.2025.100657","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to validate the Korean version of the Cancer Fatigue Scale (CFS-K) as a reliable tool for assessing cancer-related fatigue (CRF) for cancer survivors.</div></div><div><h3>Methods</h3><div>A total of 208 cancer survivors who completed active treatment participated in evaluating the reliability, construct validity, and factor structure of the CFS-K through confirmatory factor analysis (CFA). Correlations with the Functional Assessment of Chronic Illness Therapy-Fatigue (FACT-F) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 (EORTC QLQ-C30) scales were analyzed to assess construct validity.</div></div><div><h3>Results</h3><div>The CFS-K demonstrated strong psychometric properties, with high internal consistency (Cronbach’s <em>α</em> = 0.875) and CFA validated a three-factor structure (physical, cognitive, and affective fatigue) with acceptable model fit indices (normed χ<sup>2</sup> = 2.62, CFI = 0.899, TLI = 0.878, RMSEA = 0.088, SRMR = 0.069). The standardized factor loadings for all items exceeded 0.5. Construct validity was confirmed through strong correlations with FACT-F (<em>r</em> = 0.43–0.73) and significant correlations with EORTC QLQ-C30 subscales. Cancer survivors reported significantly higher fatigue levels across all subscales than controls.</div></div><div><h3>Conclusions</h3><div>The CFS-K is a reliable and valid tool for assessing multidimensional CRF in cancer survivors.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100657"},"PeriodicalIF":2.4,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Describing the minimally clinically important difference of a chemotherapy-induced peripheral neuropathy patient-reported outcome measure in young adults

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2025-01-19 DOI: 10.1016/j.apjon.2025.100656

Robert Knoerl , Emanuele Mazzola , Lindsay Frazier , Roy L. Freeman , Marilyn Hammer , Ann LaCasce , Jennifer Ligibel , Marlise R. Luskin , Donna Berry

Objective

The purpose of this secondary analysis was to characterize the reliability, validity, and minimally clinically important difference (MCID) of change scores over time of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-CIPN-20 item (QLQ-CIPN20) in young adults receiving paclitaxel or vincristine.

Methods

Fifty young adults receiving vincristine or paclitaxel for the treatment of cancer completed the QLQ-CIPN20 at three time points associated with increasing cumulative chemotherapy dose. The Subject Significance Questionnaire was completed at T3. The analyses were focused on the calculation of floor and ceiling effects, internal consistency reliability, longitudinal validity, construct validity, and the MCID using an anchor-based approach for the QLQ-CIPN20 sensory and motor subscales.

Results

By T3, 50% and 52% of participants reported QLQ-CIPN20 sensory and motor subscale scores at the floor, respectively. The internal consistency reliability of the sensory (α = 0.83) and motor (α = 0.89) subscales was strong. The Cohen’s d from T1 to T3 for the QLQ-CIPN20 sensory (d = −0.57) and motor (d = −0.47) subscales were small to moderate. There were low to moderate correlations between QLQ-CIPN20 sensory (r = 0.45) and motor (r = 0.27) subscale scores and vincristine cumulative dose. The MCID for worsening QLQ-CIPN20 sensory and motor subscale scores was 14.37 and 9.57, respectively (P < 0.01).

Conclusions

Study results provided preliminary evidence surrounding the MCID for worsening of QLQ-CIPN20 scores using an anchor based on young adults' perceived change in CIPN severity. Further research is needed to develop psychometrically sound CIPN patient-reported outcome measures to effectively evaluate the impact of CIPN interventions among young adults.

{"title":"Describing the minimally clinically important difference of a chemotherapy-induced peripheral neuropathy patient-reported outcome measure in young adults","authors":"Robert Knoerl , Emanuele Mazzola , Lindsay Frazier , Roy L. Freeman , Marilyn Hammer , Ann LaCasce , Jennifer Ligibel , Marlise R. Luskin , Donna Berry","doi":"10.1016/j.apjon.2025.100656","DOIUrl":"10.1016/j.apjon.2025.100656","url":null,"abstract":"<div><h3>Objective</h3><div>The purpose of this secondary analysis was to characterize the reliability, validity, and minimally clinically important difference (MCID) of change scores over time of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-CIPN-20 item (QLQ-CIPN20) in young adults receiving paclitaxel or vincristine.</div></div><div><h3>Methods</h3><div>Fifty young adults receiving vincristine or paclitaxel for the treatment of cancer completed the QLQ-CIPN20 at three time points associated with increasing cumulative chemotherapy dose. The Subject Significance Questionnaire was completed at T3. The analyses were focused on the calculation of floor and ceiling effects, internal consistency reliability, longitudinal validity, construct validity, and the MCID using an anchor-based approach for the QLQ-CIPN20 sensory and motor subscales.</div></div><div><h3>Results</h3><div>By T3, 50% and 52% of participants reported QLQ-CIPN20 sensory and motor subscale scores at the floor, respectively. The internal consistency reliability of the sensory (<em>α</em> = 0.83) and motor (<em>α</em> = 0.89) subscales was strong. The Cohen’s <em>d</em> from T1 to T3 for the QLQ-CIPN20 sensory (<em>d</em> = −0.57) and motor (<em>d</em> = −0.47) subscales were small to moderate. There were low to moderate correlations between QLQ-CIPN20 sensory (<em>r</em> = 0.45) and motor (<em>r</em> = 0.27) subscale scores and vincristine cumulative dose. The MCID for worsening QLQ-CIPN20 sensory and motor subscale scores was 14.37 and 9.57, respectively (<em>P</em> < 0.01).</div></div><div><h3>Conclusions</h3><div>Study results provided preliminary evidence surrounding the MCID for worsening of QLQ-CIPN20 scores using an anchor based on young adults' perceived change in CIPN severity. Further research is needed to develop psychometrically sound CIPN patient-reported outcome measures to effectively evaluate the impact of CIPN interventions among young adults.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100656"},"PeriodicalIF":2.4,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring experiences and needs among children with cancer undergoing peripherally inserted central catheter insertion: A qualitative study

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2025-01-09 DOI: 10.1016/j.apjon.2025.100654

Chengyang Li , Chunfeng Wang , Xueting Zhuang , Ying Wang , Yong Wu , Rong Hu

Objective

This study aimed to explore the experiences of children with cancer undergoing peripherally inserted central catheter (PICC) insertion.

Methods

This study employed a descriptive qualitative approach. A total of 20 children undergoing PICC insertion were enrolled through purposive sampling. Semi-structured interviews, supplemented by draw-and-tell techniques, were conducted to collect data. Thematic analysis method was employed to analyze the interview data.

Results

Four themes and 11 subthemes were identified regarding the experience of peripherally inserted central catheter insertion in pediatric cancer patients, including (1) uncertainty (unknown procedure and lack of confidence); (2) high sensitivity (vulnerable to environmental influences and care what others think); (3) psychophysical changes (stress response, physical discomfort, disruption of daily routines, and accepted with pleasure); and (4) multidimensional needs (information, comfort, and self-actualization needs).

Conclusions

The findings underscore the importance of gaining a deeper understanding of the symptoms and needs of pediatric cancer patients undergoing PICC insertion. By appreciating and honoring children’s voices, we can effectively cater to their distinct worries and guarantee they get the care and consideration they merit.

{"title":"Exploring experiences and needs among children with cancer undergoing peripherally inserted central catheter insertion: A qualitative study","authors":"Chengyang Li , Chunfeng Wang , Xueting Zhuang , Ying Wang , Yong Wu , Rong Hu","doi":"10.1016/j.apjon.2025.100654","DOIUrl":"10.1016/j.apjon.2025.100654","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to explore the experiences of children with cancer undergoing peripherally inserted central catheter (PICC) insertion.</div></div><div><h3>Methods</h3><div>This study employed a descriptive qualitative approach. A total of 20 children undergoing PICC insertion were enrolled through purposive sampling. Semi-structured interviews, supplemented by draw-and-tell techniques, were conducted to collect data. Thematic analysis method was employed to analyze the interview data.</div></div><div><h3>Results</h3><div>Four themes and 11 subthemes were identified regarding the experience of peripherally inserted central catheter insertion in pediatric cancer patients, including (1) uncertainty (unknown procedure and lack of confidence); (2) high sensitivity (vulnerable to environmental influences and care what others think); (3) psychophysical changes (stress response, physical discomfort, disruption of daily routines, and accepted with pleasure); and (4) multidimensional needs (information, comfort, and self-actualization needs).</div></div><div><h3>Conclusions</h3><div>The findings underscore the importance of gaining a deeper understanding of the symptoms and needs of pediatric cancer patients undergoing PICC insertion. By appreciating and honoring children’s voices, we can effectively cater to their distinct worries and guarantee they get the care and consideration they merit.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100654"},"PeriodicalIF":2.4,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143178927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decomposition analysis of lung cancer and COPD mortality attributable to ambient PM2.5 in China (1990–2021)

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2025-01-07 DOI: 10.1016/j.apjon.2025.100653

Xiaoxue Liu , Haoyun Zhou , Xun Yi , Xinyu Zhang , Yanan Lu , Wei Zhou , Yunzhao Ren , Chuanhua Yu

Objective

This study aimed to evaluate the long-term trends in lung cancer (LC) and chronic obstructive pulmonary disease (COPD) mortality attributable to particulate matter (PM_2.5) in China and to identify the contributions of population aging and other risk factors to changes in mortality rates.

Methods

Using data from 1991 to 2021, we assessed trends in LC and COPD deaths attributable to PM_2.5 through linear regression. Decomposition analysis was conducted to determine the extent to which changes in mortality rates were driven by demographic and non-demographic factors.

Results

The crude mortality rates attributable to PM_2.5 increased significantly for LC (500.40%) and COPD (85.26%). From 1990 to 2021, LC mortality attributable to PM_2.5 increased annually by 4.11% (95% CI: 3.64%, 4.59%), while COPD mortality decreased annually by 1.23% (95% CI: −0.82%, −1.65%). Decomposition analysis revealed that 43.0% of the increase in LC mortality was due to population aging, and 57.0% was attributed to changes in other risk factors. For COPD, population aging contributed to an 18.547/100,000 increase, whereas other risk factors reduced mortality by 10.628/100,000.

Conclusions

The findings highlight the critical roles of population aging and risk factor modification in LC and COPD mortality trends. Interventions to address aging-related vulnerabilities and air pollution control are essential to mitigate future health burdens.

{"title":"Decomposition analysis of lung cancer and COPD mortality attributable to ambient PM2.5 in China (1990–2021)","authors":"Xiaoxue Liu , Haoyun Zhou , Xun Yi , Xinyu Zhang , Yanan Lu , Wei Zhou , Yunzhao Ren , Chuanhua Yu","doi":"10.1016/j.apjon.2025.100653","DOIUrl":"10.1016/j.apjon.2025.100653","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the long-term trends in lung cancer (LC) and chronic obstructive pulmonary disease (COPD) mortality attributable to particulate matter (PM<sub>2.5</sub>) in China and to identify the contributions of population aging and other risk factors to changes in mortality rates.</div></div><div><h3>Methods</h3><div>Using data from 1991 to 2021, we assessed trends in LC and COPD deaths attributable to PM<sub>2.5</sub> through linear regression. Decomposition analysis was conducted to determine the extent to which changes in mortality rates were driven by demographic and non-demographic factors.</div></div><div><h3>Results</h3><div>The crude mortality rates attributable to PM<sub>2.5</sub> increased significantly for LC (500.40%) and COPD (85.26%). From 1990 to 2021, LC mortality attributable to PM<sub>2.5</sub> increased annually by 4.11% (95% CI: 3.64%, 4.59%), while COPD mortality decreased annually by 1.23% (95% CI: −0.82%, −1.65%). Decomposition analysis revealed that 43.0% of the increase in LC mortality was due to population aging, and 57.0% was attributed to changes in other risk factors. For COPD, population aging contributed to an 18.547/100,000 increase, whereas other risk factors reduced mortality by 10.628/100,000.</div></div><div><h3>Conclusions</h3><div>The findings highlight the critical roles of population aging and risk factor modification in LC and COPD mortality trends. Interventions to address aging-related vulnerabilities and air pollution control are essential to mitigate future health burdens.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100653"},"PeriodicalIF":2.4,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preliminary testing for affiliate stigma scale: A reliable and valid stigma measure for caregivers of women with breast cancer

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2025-01-01 DOI: 10.1016/j.apjon.2024.100652

Xiaofan Bu , Xi Chen , Lu Luo , Rongrong Fan , Ling Jiang , Xiangyu Liu , Doris Y.P. Leung

Objective

Families of breast cancer patients may face discrimination and societal rejection due to prevailing myths, misconceptions and causal beliefs related to breast cancer. This study aims to develop and validate a measurement tool that is sensitive to the affiliate stigma experienced by caregivers of women with breast cancer.

Methods

The scale was developed in two phases: (1) item generation based on interviews amongst 18 caregivers of women with breast cancer; (2) psychometric properties of the scale, including content validity, structural validity, and internal consistency reliability. Data were collected from May to June 2023 in 426 caregivers of women with breast cancer from 5 tertiary A hospitals.

Results

An exploratory factor analysis produced a 24-item scale across four dimensions, including internal stigma, social isolation, perceived stigma, and reaction. The scale showed good internal consistency and test–retest reliability. The total score of the scale was significantly and positively correlated with scores in caregiving burden and negatively correlated with scores in self-esteem and in social support. The item-level content validity index fell within the range of 0.8–1.0.

Conclusions

This is a valid and reliable instrument captured the spectrum of stigma relevant to caregivers of women with breast cancer and may serve as a unique instrument that can be used globally. This study is a step forward for stigma-related studies among caregivers of women with breast cancer and provides a reference for developing effective interventions for those with potentially stigmatized conditions.

{"title":"Preliminary testing for affiliate stigma scale: A reliable and valid stigma measure for caregivers of women with breast cancer","authors":"Xiaofan Bu , Xi Chen , Lu Luo , Rongrong Fan , Ling Jiang , Xiangyu Liu , Doris Y.P. Leung","doi":"10.1016/j.apjon.2024.100652","DOIUrl":"10.1016/j.apjon.2024.100652","url":null,"abstract":"<div><h3>Objective</h3><div>Families of breast cancer patients may face discrimination and societal rejection due to prevailing myths, misconceptions and causal beliefs related to breast cancer. This study aims to develop and validate a measurement tool that is sensitive to the affiliate stigma experienced by caregivers of women with breast cancer.</div></div><div><h3>Methods</h3><div>The scale was developed in two phases: (1) item generation based on interviews amongst 18 caregivers of women with breast cancer; (2) psychometric properties of the scale, including content validity, structural validity, and internal consistency reliability. Data were collected from May to June 2023 in 426 caregivers of women with breast cancer from 5 tertiary A hospitals.</div></div><div><h3>Results</h3><div>An exploratory factor analysis produced a 24-item scale across four dimensions, including internal stigma, social isolation, perceived stigma, and reaction. The scale showed good internal consistency and test–retest reliability. The total score of the scale was significantly and positively correlated with scores in caregiving burden and negatively correlated with scores in self-esteem and in social support. The item-level content validity index fell within the range of 0.8–1.0.</div></div><div><h3>Conclusions</h3><div>This is a valid and reliable instrument captured the spectrum of stigma relevant to caregivers of women with breast cancer and may serve as a unique instrument that can be used globally. This study is a step forward for stigma-related studies among caregivers of women with breast cancer and provides a reference for developing effective interventions for those with potentially stigmatized conditions.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100652"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and psychometric testing of a self-management scale for cancer survivors with radiotherapy/chemotherapy-induced oral mucositis in China

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2024-12-30 DOI: 10.1016/j.apjon.2024.100650

Hanfei Cui , Qingkun Han , Yulian Wei , Juan Qiao , Xiaohong Ji , Yuanyuan Li , Xuebing Jing , Xiaojie Fang

Objective

This study aims to develop and validate a self-management scale for radiotherapy/chemotherapy-induced oral mucositis (SMS-RIOM/CIOM) in cancer survivors, addressing the need for a comprehensive tool to assess self-management capabilities.

Methods

This study employed a two-phase process: (1) initial scale development through literature review, semi-structured interviews, and expert consultations, and (2) psychometric testing with 420 cancer survivors from five wards of Zibo Hospital. The psychometric evaluation included item analysis, content validity testing, reliability assessments, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA).

Results

The finalized SMS-RIOM/CIOM consists of 15 items across four dimensions: medication management, oral pain management, disease monitoring, and daily life management. EFA explained 77.322% of the total variance, while CFA demonstrated an excellent model fit (χ²/df=1.909, RMSEA=0.064, RMR=0.052, GFI=0.911, CFI=0.964, NFI=0.928, TLI=0.955, IFI=0.964). Reliability metrics were robust, including Cronbach's alpha of 0.902, split-half reliability of 0.849, test-retest reliability of 0.862, and a scale content validity index of 0.910.

Conclusions

The SMS-RIOM/CIOM is a reliable and valid tool for assessing self-management in cancer survivors with RIOM/CIOM. It provides valuable insights for clinical practice, enabling targeted interventions to improve self-management and enhance the quality of life for cancer survivors. Further research is recommended to validate its application across diverse populations and healthcare settings.

{"title":"Development and psychometric testing of a self-management scale for cancer survivors with radiotherapy/chemotherapy-induced oral mucositis in China","authors":"Hanfei Cui , Qingkun Han , Yulian Wei , Juan Qiao , Xiaohong Ji , Yuanyuan Li , Xuebing Jing , Xiaojie Fang","doi":"10.1016/j.apjon.2024.100650","DOIUrl":"10.1016/j.apjon.2024.100650","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to develop and validate a self-management scale for radiotherapy/chemotherapy-induced oral mucositis (SMS-RIOM/CIOM) in cancer survivors, addressing the need for a comprehensive tool to assess self-management capabilities.</div></div><div><h3>Methods</h3><div>This study employed a two-phase process: (1) initial scale development through literature review, semi-structured interviews, and expert consultations, and (2) psychometric testing with 420 cancer survivors from five wards of Zibo Hospital. The psychometric evaluation included item analysis, content validity testing, reliability assessments, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA).</div></div><div><h3>Results</h3><div>The finalized SMS-RIOM/CIOM consists of 15 items across four dimensions: medication management, oral pain management, disease monitoring, and daily life management. EFA explained 77.322% of the total variance, while CFA demonstrated an excellent model fit (χ²/df=1.909, RMSEA=0.064, RMR=0.052, GFI=0.911, CFI=0.964, NFI=0.928, TLI=0.955, IFI=0.964). Reliability metrics were robust, including Cronbach's alpha of 0.902, split-half reliability of 0.849, test-retest reliability of 0.862, and a scale content validity index of 0.910.</div></div><div><h3>Conclusions</h3><div>The SMS-RIOM/CIOM is a reliable and valid tool for assessing self-management in cancer survivors with RIOM/CIOM. It provides valuable insights for clinical practice, enabling targeted interventions to improve self-management and enhance the quality of life for cancer survivors. Further research is recommended to validate its application across diverse populations and healthcare settings.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100650"},"PeriodicalIF":2.4,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Latent profile analysis of fear of cancer recurrence in patients with prostate cancer: Insights into risk factors and psychological interventions

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2024-12-30 DOI: 10.1016/j.apjon.2024.100651

Ziyi Qi , Yun Dai , Sijia Hou , Binbin Zhu , Wei Wang

Objective

To explore fear of cancer recurrence (FCR) profiles in prostate cancer survivors, identify heterogeneous subgroups, and examine influencing factors to provide a reference for improving mental well-being and overall quality of life.

Methods

A convenience sample of 389 patients completed a questionnaire that assessed general and disease-related data, including the Fear of Progression Questionnaire-Short Form, Perceived Social Support Scale, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. Statistical analysis involved latent profile analysis (LPA), Bolck-Croon-Hagenaars methods and multinomial logistic regression.

Results

Three FCR profiles were identified: “Adapted” (25.7%), “Struggling” (42.2%), and “Dysregulated” (32.1%). Compared to the Adapted group, factors associated with the Struggling group included age, social support, and employment status, while factors associated with the Dysregulated group included age, social support, and time since diagnosis. From Adapted to Dysregulated, physical, cognitive, emotional, and social function declined, while dyspnea, insomnia, and financial difficulties increased.

Conclusions

The psychological problems caused by the FCR in patients with prostate cancer seriously affect their physical, emotional, cognitive and social functions. Targeted intervention strategies should be developed for different categories of patients with prostate cancer to improve the FCR and promote the health-related quality of life.

{"title":"Latent profile analysis of fear of cancer recurrence in patients with prostate cancer: Insights into risk factors and psychological interventions","authors":"Ziyi Qi , Yun Dai , Sijia Hou , Binbin Zhu , Wei Wang","doi":"10.1016/j.apjon.2024.100651","DOIUrl":"10.1016/j.apjon.2024.100651","url":null,"abstract":"<div><h3>Objective</h3><div>To explore fear of cancer recurrence (FCR) profiles in prostate cancer survivors, identify heterogeneous subgroups, and examine influencing factors to provide a reference for improving mental well-being and overall quality of life.</div></div><div><h3>Methods</h3><div>A convenience sample of 389 patients completed a questionnaire that assessed general and disease-related data, including the Fear of Progression Questionnaire-Short Form, Perceived Social Support Scale, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. Statistical analysis involved latent profile analysis (LPA), Bolck-Croon-Hagenaars methods and multinomial logistic regression.</div></div><div><h3>Results</h3><div>Three FCR profiles were identified: “Adapted” (25.7%), “Struggling” (42.2%), and “Dysregulated” (32.1%). Compared to the Adapted group, factors associated with the Struggling group included age, social support, and employment status, while factors associated with the Dysregulated group included age, social support, and time since diagnosis. From Adapted to Dysregulated, physical, cognitive, emotional, and social function declined, while dyspnea, insomnia, and financial difficulties increased.</div></div><div><h3>Conclusions</h3><div>The psychological problems caused by the FCR in patients with prostate cancer seriously affect their physical, emotional, cognitive and social functions. Targeted intervention strategies should be developed for different categories of patients with prostate cancer to improve the FCR and promote the health-related quality of life.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100651"},"PeriodicalIF":2.4,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143356661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Symptoms associated with concurrent chemoradiotherapy in patients with cervical cancer: Application of latent profile analysis and network analysis

IF 2.4 3区医学 Q1 NURSING

Asia-Pacific Journal of Oncology Nursing

Pub Date : 2024-12-27 DOI: 10.1016/j.apjon.2024.100649

Xiangyu Lu , Lingling Zheng , Xue Jin , Yuejia Wang , Shengwu Wu , Yin Lv , Hua Du

Objective

This study aims to explore symptom subgroups and influencing factors among patients undergoing concurrent chemoradiotherapy (CCRT) for cervical cancer, to construct a symptom network, and to identify core symptoms within the overall sample and its various subgroups.

Methods

A cross-sectional survey was conducted with 378 patients undergoing CCRT for cervical cancer from June 2023 to May 2024 at a tertiary hospital in Anhui Province. Participants completed the General Information Questionnaire, the Symptom Assessment Scale for Patients Undergoing CCRT for Intermediate and Advanced Cervical Cancer, and the Dyadic Coping Inventory. Latent profile analysis (LPA) identified symptom subgroups, while multivariate logistic regression examined influences on these subgroups. Symptom networks were developed using R language to analyze centrality indices and identify core symptoms.

Results

Patients were classified into three subgroups: low symptom burden (n = 200, 52.91%), moderate symptom burden with prominent intestinal response (n = 75, 19.84%), and high symptom burden (n = 103, 27.25%). Multivariate logistic regression indicated that age, tumor stage, chemotherapy frequency, and dyadic coping (DC) were predictive of subgroup membership (P < 0.05). Network analysis revealed sadness (r_s = 1.320) as the core symptom for the overall sample, nausea (r_s = 0.801) for the low symptom burden group, and vomiting (r_s = 0.705, 0.796) for both the moderate symptom burden with intestinal response prominence group and the high symptom burden group.

Conclusions

Three symptom subgroups exist among patients undergoing CCRT for cervical cancer, with sadness, nausea, and vomiting identified as core symptoms. Health care professionals should provide individualized symptom management tailored to these subgroups.

{"title":"Symptoms associated with concurrent chemoradiotherapy in patients with cervical cancer: Application of latent profile analysis and network analysis","authors":"Xiangyu Lu , Lingling Zheng , Xue Jin , Yuejia Wang , Shengwu Wu , Yin Lv , Hua Du","doi":"10.1016/j.apjon.2024.100649","DOIUrl":"10.1016/j.apjon.2024.100649","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to explore symptom subgroups and influencing factors among patients undergoing concurrent chemoradiotherapy (CCRT) for cervical cancer, to construct a symptom network, and to identify core symptoms within the overall sample and its various subgroups.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted with 378 patients undergoing CCRT for cervical cancer from June 2023 to May 2024 at a tertiary hospital in Anhui Province. Participants completed the General Information Questionnaire, the Symptom Assessment Scale for Patients Undergoing CCRT for Intermediate and Advanced Cervical Cancer, and the Dyadic Coping Inventory. Latent profile analysis (LPA) identified symptom subgroups, while multivariate logistic regression examined influences on these subgroups. Symptom networks were developed using R language to analyze centrality indices and identify core symptoms.</div></div><div><h3>Results</h3><div>Patients were classified into three subgroups: low symptom burden (<em>n</em> = 200, 52.91%), moderate symptom burden with prominent intestinal response (<em>n</em> = 75, 19.84%), and high symptom burden (<em>n</em> = 103, 27.25%). Multivariate logistic regression indicated that age, tumor stage, chemotherapy frequency, and dyadic coping (DC) were predictive of subgroup membership (<em>P</em> < 0.05). Network analysis revealed sadness (<em>r</em><sub><em>s</em></sub> = 1.320) as the core symptom for the overall sample, nausea (<em>r</em><sub><em>s</em></sub> = 0.801) for the low symptom burden group, and vomiting (<em>r</em><sub><em>s</em></sub> = 0.705, 0.796) for both the moderate symptom burden with intestinal response prominence group and the high symptom burden group.</div></div><div><h3>Conclusions</h3><div>Three symptom subgroups exist among patients undergoing CCRT for cervical cancer, with sadness, nausea, and vomiting identified as core symptoms. Health care professionals should provide individualized symptom management tailored to these subgroups.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"12 ","pages":"Article 100649"},"PeriodicalIF":2.4,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0