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Research Letter: Exploring the utility of ketamine in child and adolescent mental health: Perspectives of psychiatrists. 研究信函:探索氯胺酮在儿童和青少年心理健康中的作用:精神科医生的观点。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-01 Epub Date: 2024-08-05 DOI: 10.1177/00048674241268229
Sarthak Gandhi, Simon Craig, Michael Gordon
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引用次数: 0
Exploring the reliability and profile of frequent mental health presentations using different methods: An observational study using statewide ambulance data over a 4-year period. 使用不同方法探索频繁出现的精神疾病的可靠性和概况:利用全州救护车 4 年间的数据进行观察研究。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-01 Epub Date: 2024-10-26 DOI: 10.1177/00048674241289016
Anthony Hew, Jesse T Young, Bosco Rowland, Debbie Scott, Ziad Nehme, Shalini Arunogiri, Dan I Lubman

Introduction: A disproportionate number of mental health presentations to emergency services are made by frequent presenters. No current consensus definition of a frequent presenter exists. Using a statewide population-based ambulance database, this study (i) applied previous statistical methods to determine thresholds for frequent presenters, (ii) explored characteristics of the identified frequent presenter groups compared to non-frequent presenters and (iii) assessed the reliability of these methods in predicting continued frequent presenter status over time.

Methods: Statistical methods utilised in previous studies to identify frequent presenters were applied to all ambulance attendances for mental health symptoms, self-harm and alcohol and other drug issues between 1 January 2017 and 31 December 2020 in Victoria, Australia. Differences in characteristics between identified frequent and non-frequent presenter groups were determined by logistic regression analysis. The consistency of agreement of frequent presenter status over time was assessed using intraclass correlation coefficients.

Results: Thresholds for frequent presenters ranged from a mean of 5 to 39 attendances per calendar year, with groups differing in size, service use and characteristics. Compared to non-frequent presenters, frequent presenters had greater odds of being female, presenting with self-harm, experiencing social disadvantage or housing issues, involving police co-attendance and being transported to hospital. All frequent presenter definitions had poor reliability in predicting ongoing frequent presentations over time.

Conclusion: A range of methods can define frequent presenters according to thresholds of yearly service use. Reasons for identifying frequent presenters may influence the method chosen. Future studies should explore definitions that capture the dynamic nature of presentations by this group.

导言:在向急诊服务机构求助的精神疾病患者中,经常求助者所占的比例过高。目前还没有关于频繁出现者的一致定义。本研究利用全州范围内以人口为基础的救护车数据库,(i) 应用以前的统计方法来确定频繁求助者的阈值,(ii) 与非频繁求助者相比,探讨已确定的频繁求助者群体的特征,(iii) 评估这些方法在预测长期频繁求助者状态方面的可靠性:对澳大利亚维多利亚州2017年1月1日至2020年12月31日期间所有因精神健康症状、自残以及酒精和其他药物问题出诊的救护车采用了以往研究中用于识别频繁出诊者的统计方法。通过逻辑回归分析确定了频繁和非频繁出现者群体之间的特征差异。使用类内相关系数评估了在一段时间内频繁演讲者身份的一致性:结果:经常演讲者的阈值从平均每年 5 次到 39 次不等,各群体的规模、服务使用情况和特征各不相同。与非频繁求助者相比,频繁求助者中女性、自残、社会处境不利或住房问题、警方共同参与和被送往医院的几率更高。所有频繁出现者的定义在预测长期频繁出现方面的可靠性都很差:结论:根据每年使用服务的阈值,有一系列方法可以定义频繁出现者。识别频繁就诊者的原因可能会影响所选择的方法。未来的研究应探索能捕捉到这一群体就诊动态性质的定义。
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引用次数: 0
Youth suicidality risk relative to ambient temperature and heatwaves across climate zones: A time series analysis of emergency department presentations in New South Wales, Australia. 不同气候带的青少年自杀风险与环境温度和热浪的关系:澳大利亚新南威尔士州急诊科就诊情况的时间序列分析。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-01 Epub Date: 2024-10-23 DOI: 10.1177/00048674241290449
Cybele Dey, Jianyun Wu, John Uesi, Grant Sara, Michael Dudley, Katherine Knight, James G Scott, Ollie Jay, Michael Bowden, Iain E Perkes

Objective: Youth suicidality prevalence continues to rise alongside hot weather severity. Links between these two variables are underexplored. We examined associations between daily temperature and emergency department suicidality presentations by young people. We assessed these associations for five regions covering New South Wales as determined by 'climate zone' and analysed for heatwave effects as well as based on demographic subgroups.

Methods: Daily emergency department presentations for suicidality by people aged 12-24 years across New South Wales, Australia, during warmer months (November to March) from 2012 to 2019 were examined in relation to daily mean temperature and heatwaves (⩾3 consecutive days ⩾ 95th percentile of long-term daily mean temperature) and by climate zone, using a generalised additive model with negative binomial distribution. Risks for age- and sex-based subgroups were also calculated.

Results: New South Wales youth suicidality presentation rates were significantly higher on hotter days. For every 1°C rise above average daily mean temperature, youth suicidality presentations to New South Wales emergency departments increased by 1.3%. Heatwaves did not increase presentation rates beyond single-day daily mean temperature effects. These findings were predominantly replicated across climate zones and demographic subgroups, though the association between suicidality and ambient temperature was weaker in coastal regions including Eastern Sydney.

Conclusion: There is a positive linear association between ambient temperature and youth suicidality presentations to emergency departments. Risks are increased on single hot days, not only during heatwaves. Public health, broader societal approaches to heat and health system planning should consider impacts on youth suicidality of predicted increases in hot weather severity and frequency.

目的:青少年自杀率随着炎热天气的严重程度而持续上升。这两个变量之间的联系尚未得到充分研究。我们研究了每日气温与急诊科青少年自杀率之间的关联。我们根据 "气候区 "评估了新南威尔士州五个地区的这些关联,并根据热浪效应和人口亚群进行了分析:采用负二项分布的广义加法模型,研究了2012年至2019年澳大利亚新南威尔士州12-24岁人群在较热月份(11月至次年3月)因自杀而到急诊科就诊的情况与日平均气温和热浪(⩾连续3天⩾长期日平均气温的第95百分位数)的关系以及各气候区的关系。此外,还计算了基于年龄和性别分组的风险:结果:新南威尔士州青少年自杀率在高温天明显较高。日平均气温每升高1°C,到新南威尔士州急诊科就诊的青少年自杀率就会增加1.3%。除单日日平均气温的影响外,热浪并不会增加就诊率。这些发现主要在不同气候带和人口亚群中得到重复,但在包括悉尼东部在内的沿海地区,自杀与环境温度之间的关联较弱:结论:环境温度与急诊科接诊的青少年自杀率呈正线性关系。不仅在热浪期间,单个高温日的风险也会增加。公共卫生、应对热浪的更广泛的社会方法以及卫生系统规划应考虑炎热天气严重程度和频率的预计增加对青少年自杀率的影响。
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引用次数: 0
Self-poisoning in young Australians: The impact of COVID-19 and recent trends following easing of restrictions. 澳大利亚年轻人的自毒行为:COVID-19 的影响以及放宽限制后的最新趋势。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-01 Epub Date: 2024-11-18 DOI: 10.1177/00048674241291321
Nicholas A Buckley, Firouzeh Noghrehchi, Rohan A Elliott, Carol Wylie, Nick Merwood, Lauren Benger, Jared Brown, Rose Cairns

Introduction: Self-poisoning is the most common form of hospitalised self-harm in young people and has been increasing over the last decade. The COVID-19 pandemic was associated with further increases in self-harm in adolescents. There are limited data on changes after pandemic restrictions ended. This study aimed to describe recent trends in self-poisoning in young people.

Setting: Australia 2018-2023.

Methods: A retrospective analysis of self-poisoning calls to Australia's poisons information centres. Intentional poisoning exposures in people aged 5-19 years were included in the main analysis. We also examined intentional poisonings in people aged 20 and over for comparison. We used interrupted time-series analysis to estimate the impact of COVID-19 (March 2020) and 're-opening' (December 2021), when many restrictions were lifted in Australia. We compared effects in the jurisdictions with most disruptions and lockdowns with other jurisdictions.

Results: There were 201,755 self-poisonings documented, 64% female, with 19,946 children (aged 5-14, 9.9%) and 44,388 adolescents (aged 15-19, 22.0%). There was a steep increase in the rate of poisoning in female children and adolescents - with the annual increase being 1.361 (95% confidence interval = [1.074, 1.735]) and 1.154 (95% confidence interval = [1.049, 1.283]) times faster than pre-pandemic trends in these two groups between March 2020 and December 2021. Following relaxation of restrictions, there was a sudden drop and then slow decline in self-poisonings (despite rising COVID-19 infection rates). There was an overall 29.6% increase in intentional poisonings in young people over the study period. This is markedly more pronounced among young females (37.0%) vs males (11.2%). There were substantial jurisdictional variations, with larger increases in Victoria, Tasmania and the Australian Capital Territory.

Conclusion: There has been a marked increase in child and adolescent female self-poisonings over the last 6 years, with increases strongly associated with COVID-19 pandemic restrictions but persisting after their removal.

简介自毒是青少年最常见的住院自残形式,在过去十年中一直呈上升趋势。COVID-19 大流行与青少年自我伤害的进一步增加有关。关于大流行限制结束后的变化数据有限。本研究旨在描述青少年自我伤害的最新趋势:澳大利亚2018-2023年:对澳大利亚毒物信息中心接到的自毒电话进行回顾性分析。主要分析包括 5-19 岁人群的故意中毒事件。我们还研究了 20 岁及以上人群的故意中毒事件,以进行比较。我们使用间断时间序列分析来估计 COVID-19 (2020 年 3 月)和 "重新开放"(2021 年 12 月)的影响,届时澳大利亚将取消许多限制。我们比较了中断和封锁最多的辖区与其他辖区的影响:记录在案的自我中毒事件有 201,755 起,64% 为女性,其中有 19,946 名儿童(5-14 岁,9.9%)和 44,388 名青少年(15-19 岁,22.0%)。在 2020 年 3 月至 2021 年 12 月期间,女性儿童和青少年的中毒率急剧上升,年增长率分别为流行前趋势的 1.361 倍(95% 置信区间=[1.074, 1.735])和 1.154 倍(95% 置信区间=[1.049, 1.283])。限制放宽后,自毒人数突然下降,然后缓慢下降(尽管 COVID-19 感染率上升)。在研究期间,青少年故意中毒事件总体增加了 29.6%。年轻女性(37.0%)与男性(11.2%)之间的差异更为明显。各辖区之间存在很大差异,维多利亚州、塔斯马尼亚州和澳大利亚首都直辖区的增幅较大:结论:在过去 6 年中,儿童和青少年女性自我中毒事件显著增加,其增加与 COVID-19 大流行限制密切相关,但在取消限制后仍持续存在。
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引用次数: 0
Cumulative incidence of adolescent mental disorders following childhood maltreatment: An Australian longitudinal population cohort study.
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-26 DOI: 10.1177/00048674241307150
Melissa J Green, Oliver J Watkeys, Kirstie O'Hare, Stacy Tzoumakis, Kristin R Laurens, Kimberlie Dean, Felicity Harris, Vaughan J Carr
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引用次数: 0
Cognitive impairment in older people accessing public mental health services across Australia and New Zealand: Implications for clinical practice, workforce development and service provision.
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-26 DOI: 10.1177/00048674241307147
Roderick McKay, Anne Wand, Gary Cheung

Assessment and management of older people with cognitive impairment, especially those associated with psychiatric symptoms; are recognised as core capabilities of old age psychiatrists. Bi-national collections of HoNOS65+/HoNOS reveal that over 40% of older people entering public mental health services across Australia and New Zealand have a clinically significant rating on the HoNOS65+/HoNOS cognitive problem scale, with rates increasing with age, and significant regional variability. The high rates of cognitive impairment in these data reinforce the need for all mental health clinicians working with older people to have the capability to assess people with cognitive impairment. Once cognitive impairment is identified, clinicians must be equipped to incorporate the implications into individualised management plans, appropriate referral pathways and community support services. Such skills cannot be the sole responsibility of old age psychiatrists or aged care psychiatry services given the significant number of older people seen by adult mental health services. Regional variability in rates of cognitive impairment raises significant questions regarding variation in service eligibility criteria, equity of access to appropriate mental health care and the availability of a workforce and clinical environments that can meet the needs of older people with cognitive impairment. Finally, psychiatry trainees must learn about working with older people with various degrees of cognitive impairment as part of providing high-quality psychiatric care for an ageing population.

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引用次数: 0
The safety of psilocybin-assisted psychotherapy: A systematic review.
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-13 DOI: 10.1177/00048674241289024
Rosana R Freitas, Efstathia S Gotsis, Alexander T Gallo, Bernadette M Fitzgibbon, Neil W Bailey, Paul B Fitzgerald

Introduction: Psilocybin, a classical psychedelic, has been rescheduled for use in psilocybin-assisted psychotherapy for treatment-resistant depression in Australia. While evidence for its use is promising, understanding the associated risks is crucial. Accordingly, this review aims to collate adverse event data from psilocybin-assisted psychotherapy clinical trials and evaluate its definition, way of measurement and reporting.

Methods: A systematic method was employed to identify clinical trials related to the use of psilocybin-assisted psychotherapy in clinical populations that reported on adverse events. The quality assessment focused on relevant criteria related to adverse event definition, monitoring and reporting methods.

Results: A total of 24 articles were included. The studies reported heterogeneous psilocybin doses, study designs and indications. Physical and psychological adverse events during and after psilocybin sessions were examined, revealing variations in measuring, reporting methods and occurrences. The most common adverse events during and after sessions included elevated blood pressure, headaches, nausea, vomiting, fatigue and anxiety. In addition, both suicidal ideation and behaviour were observed infrequently and mainly in participants with a history of suicidal ideation or suicide attempt(s).

Conclusion: The review highlights the need to standardise the defintion of an adverse event, including how they are measured and reported, in psychedelic clinical trials to ensure consistent reporting across studies. In addition, screening participants for suicidality history and ongoing monitoring remains important, given the potential risk identified in the literature. However, based on the available data, the safety of psilocybin-assisted psychotherapy is generally supported, and no deaths were attributed to psilocybin. Nevertheless, cautious optimism is needed due to the preliminary nature and heterogeneity of the safety data.

{"title":"The safety of psilocybin-assisted psychotherapy: A systematic review.","authors":"Rosana R Freitas, Efstathia S Gotsis, Alexander T Gallo, Bernadette M Fitzgibbon, Neil W Bailey, Paul B Fitzgerald","doi":"10.1177/00048674241289024","DOIUrl":"https://doi.org/10.1177/00048674241289024","url":null,"abstract":"<p><strong>Introduction: </strong>Psilocybin, a classical psychedelic, has been rescheduled for use in psilocybin-assisted psychotherapy for treatment-resistant depression in Australia. While evidence for its use is promising, understanding the associated risks is crucial. Accordingly, this review aims to collate adverse event data from psilocybin-assisted psychotherapy clinical trials and evaluate its definition, way of measurement and reporting.</p><p><strong>Methods: </strong>A systematic method was employed to identify clinical trials related to the use of psilocybin-assisted psychotherapy in clinical populations that reported on adverse events. The quality assessment focused on relevant criteria related to adverse event definition, monitoring and reporting methods.</p><p><strong>Results: </strong>A total of 24 articles were included. The studies reported heterogeneous psilocybin doses, study designs and indications. Physical and psychological adverse events during and after psilocybin sessions were examined, revealing variations in measuring, reporting methods and occurrences. The most common adverse events during and after sessions included elevated blood pressure, headaches, nausea, vomiting, fatigue and anxiety. In addition, both suicidal ideation and behaviour were observed infrequently and mainly in participants with a history of suicidal ideation or suicide attempt(s).</p><p><strong>Conclusion: </strong>The review highlights the need to standardise the defintion of an adverse event, including how they are measured and reported, in psychedelic clinical trials to ensure consistent reporting across studies. In addition, screening participants for suicidality history and ongoing monitoring remains important, given the potential risk identified in the literature. However, based on the available data, the safety of psilocybin-assisted psychotherapy is generally supported, and no deaths were attributed to psilocybin. Nevertheless, cautious optimism is needed due to the preliminary nature and heterogeneity of the safety data.</p>","PeriodicalId":8589,"journal":{"name":"Australian and New Zealand Journal of Psychiatry","volume":" ","pages":"48674241289024"},"PeriodicalIF":4.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142816911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor: The real-world effectiveness of lamotrigine as a mood stabilizer for those with a bipolar II disorder: A pragmatic research study.
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-12 DOI: 10.1177/00048674241303680
Gordon Parker, Nicole Russo
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引用次数: 0
Diet interventions for depression: Review and recommendations for practice.
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-04 DOI: 10.1177/00048674241289010
Heidi M Staudacher, Scott Teasdale, Caitlin Cowan, Rachelle Opie, Felice N Jacka, Tetyana Rocks

Objective: this paper aims to present the evidence for the role of diet in the prevention and treatment of depression, review the potential underlying mechanisms and provide practice recommendations for mental health clinicians.

Methods: A literature review was conducted through searches of PubMed with the search terms 'depression', 'diet', 'prevention', 'treatment' and 'mechanisms' and combinations thereof. Additional articles were identified through hand searching.

Results: Greater adherence to several healthy dietary patterns, traditional diets such as the Mediterranean diet and other diets such as the DASH diet are associated with or can treat symptoms of depression. Several limitations of the research were noted, many of which relate to inherent challenges of studying diet. Mechanisms by which dietary intervention can influence mood include the gut microbiome, modulation of inflammatory processes, reduction in oxidative stress and modulation of hypothalamic-pituitary-adrenal axis function. Recommendations for mental health clinicians to enable translation of the evidence into practice are provided.

Conclusion: Diet can play an important role in preventing and treating depression. Mental health clinicians are well placed to provide dietary counselling and to use clinical judgement in choosing the specific approach that reflects the needs of the patient but are encouraged to refer to a specialist dietitian where necessary.

{"title":"Diet interventions for depression: Review and recommendations for practice.","authors":"Heidi M Staudacher, Scott Teasdale, Caitlin Cowan, Rachelle Opie, Felice N Jacka, Tetyana Rocks","doi":"10.1177/00048674241289010","DOIUrl":"https://doi.org/10.1177/00048674241289010","url":null,"abstract":"<p><strong>Objective: </strong>this paper aims to present the evidence for the role of diet in the prevention and treatment of depression, review the potential underlying mechanisms and provide practice recommendations for mental health clinicians.</p><p><strong>Methods: </strong>A literature review was conducted through searches of PubMed with the search terms 'depression', 'diet', 'prevention', 'treatment' and 'mechanisms' and combinations thereof. Additional articles were identified through hand searching.</p><p><strong>Results: </strong>Greater adherence to several healthy dietary patterns, traditional diets such as the Mediterranean diet and other diets such as the DASH diet are associated with or can treat symptoms of depression. Several limitations of the research were noted, many of which relate to inherent challenges of studying diet. Mechanisms by which dietary intervention can influence mood include the gut microbiome, modulation of inflammatory processes, reduction in oxidative stress and modulation of hypothalamic-pituitary-adrenal axis function. Recommendations for mental health clinicians to enable translation of the evidence into practice are provided.</p><p><strong>Conclusion: </strong>Diet can play an important role in preventing and treating depression. Mental health clinicians are well placed to provide dietary counselling and to use clinical judgement in choosing the specific approach that reflects the needs of the patient but are encouraged to refer to a specialist dietitian where necessary.</p>","PeriodicalId":8589,"journal":{"name":"Australian and New Zealand Journal of Psychiatry","volume":" ","pages":"48674241289010"},"PeriodicalIF":4.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compulsory Community Treatment Orders and health outcomes for Ma-ori in New Zealand. 强制社区治疗令与新西兰毛利人的健康状况。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-01 Epub Date: 2024-09-26 DOI: 10.1177/00048674241280918
Ben Beaglehole, Chris Frampton, Giles Newton-Howes, Arahia Kirikiri, Cameron Lacey

Background: We have previously analysed outcomes for all community treatment orders commenced during a 10-year period in New Zealand. Given Te Tiriti O Waitangi obligations to scrutinise health and consider equity for Māori, we completed this analysis to consider community treatment-order outcomes according to ethnicity.

Methods: Ministry of Health databases provided demographic, service use and medication dispensing data for community treatment-order recipients between 2009 and 2018. As non-Māori on community treatment orders are older, less deprived and less likely to be diagnosed with a Psychotic Disorder, data were categorised according to age (<35/⩾35 years), level of deprivation (New Zealand Dep levels ⩽3, 4-6 and ⩾7) and diagnosis (Psychotic Disorder/non-Psychotic Disorder). The incidences of key outcome measures (admissions, community care, medication dispensing) were calculated for periods on/off community treatment orders for Māori and non-Māori to consider the differential impact of community treatment orders according to ethnicity.

Results: Māori have high rates of community treatment order utilisation and are younger, more likely to be diagnosed with a Psychotic Disorder and spend longer receiving compulsory treatment than non-Māori. Non-Māori are more likely to receive more additional depot antipsychotic medication on-community treatment orders compared with periods off-community treatment order than Māori but other clear patterns of response distinguishing between Māori and non-Māori were not present.

Conclusion: The differences between Māori and non-Māori for community treatment-order utilisation suggest the presence of structural inequity in underlying mental illness distribution and treatment provision. Māori cultural expertise at all levels of healthcare including healthcare planning and delivery is required to make advances and reduce disparity.

背景:我们之前分析了新西兰十年间开始执行的所有社区治疗令的结果。考虑到Te Tiriti O Waitangi有义务审查毛利人的健康状况并考虑其公平性,我们完成了这项分析,根据种族考虑社区治疗令的结果:卫生部数据库提供了2009年至2018年间社区治疗单接受者的人口统计、服务使用和配药数据。由于接受社区治疗令的非毛利人年龄较大、贫困程度较低且被诊断出患有精神障碍的可能性较小,因此根据年龄对数据进行了分类(结果:毛利人接受社区治疗令的比例较高,而非毛利人接受社区治疗令的比例较低):与非毛利人相比,毛利人使用社区治疗令的比例较高,而且更年轻,更有可能被诊断出患有精神障碍,接受强制治疗的时间也更长。与非毛利人相比,非毛利人更有可能在接受社区治疗令期间比接受非社区治疗令期间接受更多的额外去势抗精神病药物治疗,但毛利人和非毛利人之间并不存在其他明显的反应模式:结论:毛利人和非毛利人在使用社区治疗指令方面的差异表明,在精神疾病的分布和治疗提供方面存在着结构性的不平等。各级医疗保健机构,包括医疗保健规划和提供机构,都需要具备毛利文化方面的专业知识,以便取得进步,缩小差距。
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引用次数: 0
期刊
Australian and New Zealand Journal of Psychiatry
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