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Alexithymia in Chinese patients with chronic schizophrenia: Prevalence, clinical correlates, and relationship with neurocognition and empathy 中国慢性精神分裂症患者述情障碍:患病率、临床相关性及其与神经认知和共情的关系
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-08-28 DOI: 10.1111/appy.12547
Pu Peng MD, Dongmei Wang PhD, Qianjin Wang PhD, Yanan Zhou PhD, Yuzhu Hao PhD, Shubao Chen PhD, Qiuxia Wu PhD, Tieqiao Liu PhD, Xiangyang Zhang PhD

Introduction

Alexithymia is highly prevalent and strongly related to adverse consequences in patients with schizophrenia. However, its associated factors remain largely unexplored. The present study aimed to determine the prevalence of alexithymia and its association with sociocultural characteristics, clinical symptoms, neurocognition, and empathy in 854 Chinese patients with schizophrenia.

Method

Demographic information was collected through a self-designed questionnaire. Alexithymia was assessed by the Toronto Alexithymia Scale (TAS-20). We assessed clinical symptoms, neurocognition, and empathy via the following instruments: Positive and Negative Syndrome Scale, Repeatable Battery for the Assessment of Neuropsychological Status, and Interpersonal Reactivity Index. A multiple logistic regression model was conducted to determine the independent correlates of alexithymia.

Results

Approximately one-third (n = 277, 32%) of patients with schizophrenia had alexithymia. Patients with alexithymia had significantly more severe negative symptoms, neurocognition, and empathy impairment than patients without alexithymia. Being male, negative symptoms, personal distress, empathic concern, and language functioning were independently associated with alexithymia.

Discussion

Our findings demonstrate a high prevalence of alexithymia and its strong association with clinical symptoms, neurocognition, and empathy, which calls for timely screening and intervention for alexithymia in patients with schizophrenia. Targeting impaired language function, negative symptoms, and impaired affective empathy might help reduce alexithymia and its related negative consequences.

述情障碍在精神分裂症患者中非常普遍,并与不良后果密切相关。然而,其相关因素在很大程度上仍未被探索。本研究旨在确定854例中国精神分裂症患者述情障碍的患病率及其与社会文化特征、临床症状、神经认知和共情的关系。方法:采用自行设计的调查问卷收集人口统计信息。用多伦多述情量表(TAS-20)评估述情障碍。我们通过以下工具评估临床症状、神经认知和共情:阳性和阴性综合征量表、神经心理状态评估可重复电池和人际反应指数。采用多元logistic回归模型确定述情障碍的独立相关因素。结果:大约三分之一(n = 277, 32%)的精神分裂症患者有述情障碍。与无述情障碍的患者相比,有述情障碍的患者有更严重的阴性症状、神经认知和共情障碍。男性、阴性症状、个人痛苦、共情关怀和语言功能与述情障碍独立相关。讨论:我们的研究结果表明述情障碍的高患病率及其与临床症状,神经认知和共情的密切联系,这要求及时筛查和干预精神分裂症患者述情障碍。针对语言功能受损、阴性症状和情感共情受损可能有助于减少述情障碍及其相关的负面后果。
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引用次数: 0
Addressing the Adverse Impact of Social Determinants of Mental Health: Yet Another Call to Action 解决心理健康的社会决定因素的不利影响:又一次行动呼吁
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-08-22 DOI: 10.1111/appy.12545
Allan Tasman MD
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引用次数: 0
Association of suicide with psychiatric hospitalization in Taiwan 台湾自杀与精神病院之关系。
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-08-21 DOI: 10.1111/appy.12546
Jia-Chi Shan MD, MHS, Mei-Chih Meg Tseng MD, PhD, Chin-Hao Chang PhD

Introduction

A knowledge gap exists in the relationship between suicide and psychiatric hospitalization in Asia. This study investigated inpatient service utilization before suicide and suicide risk at different periods of hospitalization in Taiwan.

Methods

Using the National Health Insurance Research Database, we applied a nested case–control design with controls being alive on the date each case died by suicide.

Results

A total of 56 939 suicide cases and 1 138 780 controls were included (2:1 male-to-female ratio). Only 5.7% of suicide cases had a history of psychiatric hospitalization in the preceding year. Patients with a history of psychiatric hospitalization were associated with a higher risk of inpatient and postdischarge suicide than those without prior hospitalization. The risk was greatest in the first postdischarge week, decreased gradually, and remained significantly elevated over 7 years after discharge. The suicide risk increased more in females. Patients with affective disorders had higher inpatient and postdischarge suicide risks than those with schizophrenia spectrum disorders.

Discussion

A low rate of psychiatric hospitalization before suicide implies that inpatient treatment of psychiatric disorders could be enhanced. Community-based approaches to suicide prevention can improve the treatment utilization of those with suicide risk and bridge continuous care from hospital to community.

导言:在亚洲,自杀与精神病住院之间的关系存在知识差距。摘要本研究旨在探讨台湾不同住院期病人自杀前的住院服务利用及自杀风险。方法:使用国家健康保险研究数据库,我们采用嵌套病例-对照设计,对照者在每个病例自杀死亡之日还活着。结果:共纳入自杀病例56 939例,对照组1 138 780例(男女比例2:1)。只有5.7%的自杀病例在前一年有精神科住院史。有精神科住院史的患者住院和出院后自杀的风险高于没有住院史的患者。风险在出院后第一周最大,逐渐降低,并在出院后7年内保持显著升高。女性的自杀风险增加得更多。情感性障碍患者的住院和出院后自杀风险高于精神分裂症谱系障碍患者。讨论:自杀前精神病住院率低,这意味着精神疾病的住院治疗可以得到加强。以社区为基础的自杀预防方法可以提高有自杀风险者的治疗利用率,并将医院和社区之间的持续护理联系起来。
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引用次数: 0
Association between postictal suppression and the therapeutic effects of electroconvulsive therapy: A systematic review 电位抑制与电休克治疗效果之间的关系:一项系统综述。
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-08-16 DOI: 10.1111/appy.12544
Mahdie Ershad Langroudi MD, Narges Shams-Alizadeh MD, Azad Maroufi MD, Khaled Rahmani PhD, Maryam Rahchamani MD

Electroconvulsive therapy (ECT) is an effective and safe medical treatment for patients with severe mood and neuropsychiatric disorders. Since the advent of ECT, extensive research has been performed to identify the predictive factors for response to ECT. In recent decades, postictal suppression on an electroencephalogram (EEG) has been considered a potential predictor of response to ECT. We aimed to investigate the direct association between postictal suppression and the therapeutic effects of ECT. In this systematic review, all articles in the field of the association between postictal suppression and the therapeutic effects of ECT published between 1990 and 2021 were identified. The full texts of these articles, which include clinical trials and retrospective and cross-sectional studies, are available in scholarly research databases and search engines, including PubMed, Google Scholar, OVID, Web of Science, and Scopus. Of all retrieved articles, eight studies, including four retrospective cohort articles and four clinical trials, met the inclusion criteria for further analyses. The findings of this study showed a significant association between postictal suppression and the therapeutic efficacy of ECT. Factors such as electrode placement, tachycardia, type of anesthetic agent, and EEG amplitude were also directly related to postictal suppression and the efficacy of ECT. Postictal suppression on EEG can be considered a predictor of response to ECT. To increase the effectiveness of treatment with ECT and increase postictal suppression, factors including electrode placement, tachycardia, type of anesthesia, and EEG amplitude should be considered, which highlights the need for further research.

电休克治疗(ECT)是一种有效且安全的治疗严重情绪和神经精神障碍的药物。自从ECT出现以来,人们进行了广泛的研究,以确定对ECT反应的预测因素。近几十年来,脑电图(EEG)的电位抑制被认为是电痉挛治疗反应的潜在预测指标。我们的目的是研究电痉挛治疗效果与电位抑制之间的直接关系。在本系统综述中,对1990年至2021年间发表的所有关于电位抑制与ECT治疗效果之间关系的文章进行了分析。这些文章的全文,包括临床试验、回顾性和横断面研究,可在学术研究数据库和搜索引擎中获得,包括PubMed、b谷歌Scholar、OVID、Web of Science和Scopus。在所有检索到的文章中,包括4篇回顾性队列文章和4项临床试验在内的8项研究符合进一步分析的纳入标准。本研究结果显示,电痉挛疗法的治疗效果与电位抑制有显著的相关性。电极放置、心动过速、麻醉剂种类、脑电图波幅等因素也与电痉挛后抑制及电痉挛疗效有直接关系。脑电图的后抑制可以被认为是电痉挛反应的预测指标。为了提高ECT治疗的有效性,增加电位抑制,需要考虑电极放置、心动过速、麻醉方式、脑电图振幅等因素,需要进一步研究。
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引用次数: 0
Loneliness in older Chinese adults amid the COVID-19 pandemic: Prevalence and associated factors COVID-19大流行期间中国老年人的孤独感:患病率及相关因素
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-08-10 DOI: 10.1111/appy.12543
Juan Ruan RN, Yan-Min Xu MEd, Bao-Liang Zhong MD, PhD

Introduction

Data on loneliness among older adults in China during the COVID-19 pandemic are still scarce. This study aimed to examine the prevalence of loneliness and identify its associated factors among older Chinese adults during the COVID-19 pandemic.

Methods

During the COVID-19 pandemic, 1268 older Chinese adults (aged 50+ years) were recruited through snowball sampling. The Chinese version of the validated six-item De Jong Gierveld Loneliness Scale was used to assess participants' recent feelings of loneliness, and a cut-off score of two or more was used to indicate the presence of loneliness.

Results

Loneliness was experienced by 37.9% of the participants in recent days. Factors significantly associated with loneliness included male sex (vs. female, OR: 1.62, p < .001), an education level of middle school and below (vs. college and above, OR: 1.50, p = .007), residing in the COVID-19 epicenter (vs. other provinces, OR: 1.48, p = .004), concern about contracting COVID-19 (OR: 1.68, p = .001), poor knowledge of COVID-19 (OR: 2.39, p = .012), and physical health problems (OR: 1.65, p < .001).

Discussion

Loneliness is common among older Chinese adults amid the COVID-19 pandemic. Targeted intervention programs may be more effective in reducing loneliness among older adults who are worried about contracting COVID-19, have poor COVID-19 knowledge, and experience physical health problems.

导言:关于2019冠状病毒病大流行期间中国老年人孤独感的数据仍然很少。本研究旨在研究2019冠状病毒病大流行期间中国老年人孤独感的流行情况,并确定其相关因素。方法:在COVID-19大流行期间,采用滚雪球抽样方法招募1268名年龄在50岁以上的中国老年人。中文版的德容·吉维尔德孤独量表(De Jong Gierveld Loneliness Scale)被用于评估参与者最近的孤独感,并使用2分或2分以上的分值来表明孤独感的存在。结果:37.9%的参与者在最近几天经历过孤独。与孤独感显著相关的因素包括男性性别(vs.女性,OR: 1.62, p)。讨论:在COVID-19大流行期间,孤独感在中国老年人中很常见。有针对性的干预方案可能更有效地减少老年人的孤独感,这些老年人担心感染COVID-19,对COVID-19知之甚少,并且有身体健康问题。
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引用次数: 3
Dialectical behavior therapy in Chinese suicidal patients with borderline personality disorder: A pilot randomized controlled trial 辩证行为疗法在中国边缘型人格障碍自杀患者中的应用:一项随机对照试验
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-08-10 DOI: 10.1111/appy.12541
Shu-I Wu MD, PhD, Hui-Chun Huang PhD, Shu-Chin Chen MA, Kathryn Korslund PhD, ABPP, Chen-Ju Lin MD, Ying Lin MD, PhD, Yi-Hung Chang MA, Hsiao-Mei Yeh MA, I-Chieh Lin MA, Yu-Wen Lin MA, Fang-Ju Sun MA, Ching-Hu Chung PhD, Shen-Ing Liu MD, PhD
We conducted a single-blind, randomized controlled trial to examine the implementation of dialectical behavior therapy (DBT) in Chinese patients with borderline personality disorder (BPD) with at least two suicidal or non-suicidal self-injurious episodes. Of the 150 BPD patients referred and screened, 60 participated in the trial and were randomly assigned to 1 year of either DBT or psychotherapy delivered by community experts in suicide prevention. Reductions in self-injurious behaviors, medical utilizations due to suicidal ideations or suicidal attempts, borderline symptoms, and psychological distress were noted in both groups. However, no between-group differences were noted at the end of treatments (Table 1). Our results suggest that BPD patients with suicidal attempts benefited equally from DBT and treatment delivered by suicide prevention experts in Taiwan. Reasons for the lack of significant between-group differences may be that although we requested patients' psychiatrists provide only general psychiatric pharmacotherapy or case management; it might be possible that DBT elements may have been infused in the treatment course. Cultural factors may include that Chinese patients tend to have negative views about sharing their own opinions in group therapy (Hansher, 2015), or to express their emotions (Chiu et al., 2019; Mingzhao et al., 1992), because these behaviors might be judged as being “too emotional,” and participants may therefore readily
{"title":"Dialectical behavior therapy in Chinese suicidal patients with borderline personality disorder: A pilot randomized controlled trial","authors":"Shu-I Wu MD, PhD,&nbsp;Hui-Chun Huang PhD,&nbsp;Shu-Chin Chen MA,&nbsp;Kathryn Korslund PhD, ABPP,&nbsp;Chen-Ju Lin MD,&nbsp;Ying Lin MD, PhD,&nbsp;Yi-Hung Chang MA,&nbsp;Hsiao-Mei Yeh MA,&nbsp;I-Chieh Lin MA,&nbsp;Yu-Wen Lin MA,&nbsp;Fang-Ju Sun MA,&nbsp;Ching-Hu Chung PhD,&nbsp;Shen-Ing Liu MD, PhD","doi":"10.1111/appy.12541","DOIUrl":"10.1111/appy.12541","url":null,"abstract":"We conducted a single-blind, randomized controlled trial to examine the implementation of dialectical behavior therapy (DBT) in Chinese patients with borderline personality disorder (BPD) with at least two suicidal or non-suicidal self-injurious episodes. Of the 150 BPD patients referred and screened, 60 participated in the trial and were randomly assigned to 1 year of either DBT or psychotherapy delivered by community experts in suicide prevention. Reductions in self-injurious behaviors, medical utilizations due to suicidal ideations or suicidal attempts, borderline symptoms, and psychological distress were noted in both groups. However, no between-group differences were noted at the end of treatments (Table 1). Our results suggest that BPD patients with suicidal attempts benefited equally from DBT and treatment delivered by suicide prevention experts in Taiwan. Reasons for the lack of significant between-group differences may be that although we requested patients' psychiatrists provide only general psychiatric pharmacotherapy or case management; it might be possible that DBT elements may have been infused in the treatment course. Cultural factors may include that Chinese patients tend to have negative views about sharing their own opinions in group therapy (Hansher, 2015), or to express their emotions (Chiu et al., 2019; Mingzhao et al., 1992), because these behaviors might be judged as being “too emotional,” and participants may therefore readily","PeriodicalId":8618,"journal":{"name":"Asia‐Pacific Psychiatry","volume":"15 2-3","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10441453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stigma toward mental disorders and associated factors among community mental health workers in Wuhan, China 武汉社区精神卫生工作者对精神障碍的耻辱感及其相关因素
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-07-30 DOI: 10.1111/appy.12542
Mo Chen PhD, Guo-Rong Lin RN, Gui-Yang Wang MPH, Li Yang MEd, Na Lyu MEd, Chen Qian MSc, Jing-Xi Lan MSc, Yang Zhou MD, Bao-Liang Zhong PhD

Background

Stigma toward mental disorders (STMD) is a significant barrier to mental health service delivery. To improve the provision of mental health services for community-dwelling residents in China, this study investigated STMD and its associated factors in community mental health workers (CMHWs) in Wuhan, China.

Methods

In this cross-sectional study, a total of 3869 CMHWs (22.9% men and 37.1 ± 8.4 years old) were randomly selected through multistage sampling and invited to participate in this survey. The perceived devaluation-discrimination scale (PDD) and the National Mental Health Literacy Questionnaire (NMHLQ) were used to assess STMD and mental health knowledge, respectively. The presence of STMD was indicated by a mean item score of 3.0 or higher on the PDD. Multiple logistic regression was used to identify factors associated with STMD.

Results

Of the CMHWs, 41.9% had poor mental health knowledge (NMHLQ score < 80), and 18.5% exhibited STMD. In multiple regression analysis, factors significantly associated with STMD were social workers (vs. primary care physicians, OR = 1.44, p < .001), poor self-rated capacity to handle common mental health problems (vs. good, OR = 1.57, p < .001), and poor mental health knowledge (vs. NMHLQ score ≥ 80, OR = 1.46, p < .001).

Conclusion

STMD is common among Chinese CMHWs. To reduce STMD among CMHWs, training programs in mental health care skills and mental health education may be necessary.

背景对精神障碍(STMD)的耻辱感是精神卫生服务提供的一个重要障碍。为改善中国社区居民的精神卫生服务,本研究调查了武汉社区精神卫生工作者(CMHWs)的性传播疾病及其相关因素。方法采用多阶段抽样方法,随机抽取3869名cmhw参与调查,其中男性占22.9%,年龄37.1±8.4岁。分别采用认知贬值-歧视量表(PDD)和国家心理健康素养问卷(NMHLQ)对性传播疾病和心理健康知识进行评估。PDD的平均项目得分为3.0或更高,表明存在STMD。采用多元逻辑回归来确定与STMD相关的因素。结果41.9%的华裔华裔心理健康知识较差(NMHLQ评分为80分),18.5%的华裔华裔患有性传播疾病。在多元回归分析中,与性传播疾病显著相关的因素是社会工作者(相对于初级保健医生,OR = 1.44, p < .001)、处理常见心理健康问题的自评能力差(相对于良好,OR = 1.57, p < .001)和心理健康知识差(相对于NMHLQ评分≥80,OR = 1.46, p < .001)。结论STMD在中国农民工中普遍存在。为了减少cmhw中的性传播疾病,可能有必要进行心理卫生保健技能和心理卫生教育方面的培训。
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引用次数: 0
Symptoms mediate the relationship between childhood trauma and non-suicidal self-injury: A hospital-based study of adolescents with mood disorder 儿童创伤与非自杀性自伤之间的关系:一项基于医院的青少年情绪障碍研究
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-06-19 DOI: 10.1111/appy.12540
Rui Zhou MD, Ting Ji MD, Ji-Jie Zhang MD, Yin-Du Liu MD, Fei Wang PhD, Fu-Jun Jia PhD, Cai-Lan Hou PhD

Background

Childhood trauma has a significant impact on the development of adolescents, which may lead to interpersonal and psychological problems. Determining the incidence and consequences of childhood trauma in psychiatric clinical practice is of great significance.

Methods

A survey was conducted among adolescents with mood disorders. Childhood Trauma Questionnaire (CTQ), the Adolescent Non-Suicidal-Self-Injury Behavior Function Assessment Scale (ANBFAS) and a series of psychological scales were filled face to face. Path analysis was used to examine the causation structure of childhood trauma-related symptoms.

Results

A total of 117 participants (74.5%) had experienced at least one type of trauma. Interpersonal and psychological features of adolescent patients with childhood trauma were detailed in this study. The path analysis model showed that the relationships between childhood trauma and NSSI were mediated by depressive symptoms and thinking disorders, respectively, whereas depressive symptoms individually mediated the correlation between childhood trauma and sleep disturbances in adolescent patients with psychiatric disorders (χ2/df = 1.23).

Conclusion

For adolescent patients with childhood trauma, psychological counseling for interpersonal relationships should start with families and peers. It is important to treat their depressive symptoms and thinking disorders and alleviate NSSI behavior and sleep disorders.

童年创伤对青少年的发展有重要影响,可能导致人际关系和心理问题。确定儿童创伤的发生率和后果在精神病学临床实践中具有重要意义。方法对青少年情绪障碍患者进行问卷调查。面对面填写儿童创伤问卷(CTQ)、青少年非自杀-自伤行为功能评定量表(ANBFAS)及一系列心理量表。采用通径分析探讨儿童创伤相关症状的病因结构。结果117例(74.5%)患者至少经历过一种创伤。本研究详细探讨青少年创伤患者的人际关系及心理特征。通径分析模型显示,童年创伤与自伤之间的关系分别由抑郁症状和思维障碍介导,而抑郁症状单独介导青少年精神障碍患者童年创伤与睡眠障碍之间的相关性(χ2/df = 1.23)。结论青少年创伤患者的人际关系心理疏导应从家庭和同伴入手。重要的是治疗他们的抑郁症状和思维障碍,减轻自伤行为和睡眠障碍。
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引用次数: 1
Perinatal psychotropic dispensing: A descriptive population-based study in New Zealand 围产期精神药物配药:新西兰一项基于人群的描述性研究
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-06-15 DOI: 10.1111/appy.12539
Lucy Charlotte Broughton PGDipClinPharm, Natalie Hughes-Medlicott PhD, Jiaxu Zeng PhD, Alesha Smith PhD

Introduction

Decisions about using psychotropics during pregnancy are complex as risks of untreated illness are balanced against risks of fetal exposure to medication. The objective was to describe perinatal psychotropic dispensing patterns in New Zealand.

Methods

Nationwide data from the New Zealand National Maternity Collection between January 1, 2011 and December 31, 2017 identified 399 715 pregnancies. These were linked with dispensing records to determine the proportion of pregnancies during which at least 1 psychotropic was dispensed. Proportions were calculated separately for each class, year, pregnancy period, and across maternal characteristics. The pattern of dispensing (including discontinuations) was also determined for the 25 841 women who were dispensed at least 1 psychotropic drug prior to pregnancy.

Results

From the 399 715 pregnancies in the study cohort, 6.6% were dispensed at least 1 psychotropic during pregnancy. Antidepressants (5.1%) were the most dispensed, followed by hypnotics (1.2%), anxiolytics (0.7%), and antipsychotics (0.7%). From the 25 841 pregnancies during which a psychotropic was dispensed pre-pregnancy, 91% and 90% discontinued hypnotics and anxiolytics respectively, prior to or during pregnancy. This was followed by lithium (71%), antipsychotics (66%), and antidepressants (66%).

Discussion

Dispensing of psychotropics during pregnancy occurs in approximately 6.6% of pregnancies in New Zealand. Two-thirds of women (66%) on antidepressants or antipsychotics discontinue dispensing before or during pregnancy. This may have implications for maternal mental health, suggesting there is a need to investigate how healthcare providers and women are making decisions about psychotropic use during pregnancy.

关于在怀孕期间使用精神药物的决定是复杂的,因为未治疗疾病的风险与胎儿接触药物的风险相平衡。目的是描述在新西兰围产期精神药物分配模式。方法2011年1月1日至2017年12月31日期间,新西兰国家孕产妇收集的全国数据确定了399 715例妊娠。这些数据与配药记录相关联,以确定至少配药一种精神药物的怀孕比例。分别计算每个班级、年份、妊娠期和母亲特征的比例。还确定了25841名在怀孕前至少服用过一种精神药物的妇女的配药模式(包括停药)。结果在399715例妊娠中,6.6%的孕妇在妊娠期间至少使用了1种精神药物。使用最多的是抗抑郁药(5.1%),其次是催眠药(1.2%)、抗焦虑药(0.7%)和抗精神病药(0.7%)。在25841名怀孕期间在怀孕前服用精神药物的孕妇中,分别有91%和90%的孕妇在怀孕前或怀孕期间停止服用催眠药和抗焦虑药。其次是锂(71%)、抗精神病药(66%)和抗抑郁药(66%)。在新西兰,约6.6%的孕妇在怀孕期间配发精神药物。三分之二(66%)服用抗抑郁或抗精神病药物的妇女在怀孕前或怀孕期间停止配药。这可能对孕产妇心理健康产生影响,表明有必要调查医疗保健提供者和妇女如何在怀孕期间决定使用精神药物。
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引用次数: 0
Gender-specific associations between types of childhood maltreatment and major depressive disorder: A matched case–control study 儿童虐待类型与重度抑郁症之间的性别特异性关联:一项匹配的病例对照研究
IF 3.5 3区 医学 Q2 PSYCHIATRY Pub Date : 2023-06-06 DOI: 10.1111/appy.12538
Jia Zhou Msc, Lei Feng MD, Changqing Hu MSc, Christine Pao MSc, Zhiyong Zou MD, Gang Wang MD

Introduction

Major depressive disorder (MDD) has been found to be nearly twice as prevalent in females as in males. One hypothesis proposed that abused females were particularly prone to MDD. We aim to examine the sex-specific associations between various types of childhood trauma and MDD.

Methods

In this study, 290 outpatients diagnosed with MDD were recruited from Beijing Anding Hospital, and 290 healthy volunteers were recruited from neighborhoods nearby the hospital, with sex, age, and family history matched. Childhood Trauma Questionnaire-Short Form (CTQ-SF) developed by Bernstein et al. was used to assess the severity of five different types of childhood abuse and neglect. McNemar's test and conditional logistic regression models with potential confounders (i.e., marital status, educational level, and body mass index) controlled were used to explore the sex-specific associations between different types of childhood maltreatment and MDD.

Results

In the full sample, patients with MDD showed a significant higher rate of any childhood maltreatment (i.e., emotional abuse, sexual abuse, physical abuse, emotional neglect, and physical neglect). Among females, all types of childhood abuse were statistically significant. For males, significant differences were only found in emotional abuse and in emotional neglect.

Conclusion

It would appear that MDD in the outpatients is associated with any type of childhood trauma in women and emotional abuse or neglect in men.

重度抑郁症(MDD)在女性中的患病率几乎是男性的两倍。一种假说认为受虐待的女性特别容易患重度抑郁症。我们的目的是研究不同类型的童年创伤和重度抑郁症之间的性别特异性关联。方法在北京安定医院招募290名诊断为重度抑郁症的门诊患者,在医院附近社区招募290名性别、年龄、家族史相匹配的健康志愿者。伯恩斯坦等人开发的儿童创伤问卷-短表格(CTQ-SF)被用来评估五种不同类型的儿童虐待和忽视的严重程度。采用McNemar检验和控制潜在混杂因素(如婚姻状况、教育水平和体重指数)的条件logistic回归模型,探讨不同类型儿童虐待与重度抑郁症之间的性别特异性关联。结果在整个样本中,重度抑郁症患者表现出更高的儿童虐待率(即情绪虐待、性虐待、身体虐待、情绪忽视和身体忽视)。在女性中,所有类型的童年虐待都有统计学意义。对于男性来说,只有在情感虐待和情感忽视方面存在显著差异。结论门诊患者的重度抑郁症与女性的任何类型的童年创伤和男性的情感虐待或忽视有关。
{"title":"Gender-specific associations between types of childhood maltreatment and major depressive disorder: A matched case–control study","authors":"Jia Zhou Msc,&nbsp;Lei Feng MD,&nbsp;Changqing Hu MSc,&nbsp;Christine Pao MSc,&nbsp;Zhiyong Zou MD,&nbsp;Gang Wang MD","doi":"10.1111/appy.12538","DOIUrl":"10.1111/appy.12538","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Major depressive disorder (MDD) has been found to be nearly twice as prevalent in females as in males. One hypothesis proposed that abused females were particularly prone to MDD. We aim to examine the sex-specific associations between various types of childhood trauma and MDD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this study, 290 outpatients diagnosed with MDD were recruited from Beijing Anding Hospital, and 290 healthy volunteers were recruited from neighborhoods nearby the hospital, with sex, age, and family history matched. Childhood Trauma Questionnaire-Short Form (CTQ-SF) developed by Bernstein et al. was used to assess the severity of five different types of childhood abuse and neglect. McNemar's test and conditional logistic regression models with potential confounders (i.e., marital status, educational level, and body mass index) controlled were used to explore the sex-specific associations between different types of childhood maltreatment and MDD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In the full sample, patients with MDD showed a significant higher rate of any childhood maltreatment (i.e., emotional abuse, sexual abuse, physical abuse, emotional neglect, and physical neglect). Among females, all types of childhood abuse were statistically significant. For males, significant differences were only found in emotional abuse and in emotional neglect.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>It would appear that MDD in the outpatients is associated with any type of childhood trauma in women and emotional abuse or neglect in men.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8618,"journal":{"name":"Asia‐Pacific Psychiatry","volume":"15 2-3","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10430160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Asia‐Pacific Psychiatry
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