{"title":"Acknowledgement to the Reviewers","authors":"","doi":"10.1159/000512261","DOIUrl":"https://doi.org/10.1159/000512261","url":null,"abstract":"","PeriodicalId":8624,"journal":{"name":"Audiology and Neurotology","volume":"82 1","pages":"345 - 346"},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78381562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Front & Back Matter","authors":"","doi":"10.1159/000510230","DOIUrl":"https://doi.org/10.1159/000510230","url":null,"abstract":"","PeriodicalId":8624,"journal":{"name":"Audiology and Neurotology","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78062817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Front & Back Matter","authors":"","doi":"10.1159/000508774","DOIUrl":"https://doi.org/10.1159/000508774","url":null,"abstract":"","PeriodicalId":8624,"journal":{"name":"Audiology and Neurotology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75222637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Front & Back Matter","authors":"","doi":"10.1159/000506215","DOIUrl":"https://doi.org/10.1159/000506215","url":null,"abstract":"","PeriodicalId":8624,"journal":{"name":"Audiology and Neurotology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74753416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joan G. Hewitt, R. Labadie, A. Moberly, J. Purdy, I. Schrauwen, Kareem O. Tawfik, D. Cotanche
Ksenia Aaron – Stanford University, Palo Alto, CA, USA Daniela Carvalho – UCSD Pediatric Otolaryngology, San Diego, CA, USA Wade W. Chien – National Institutes of Health, Bethesda, MD, USA Maura K. Cosetti – New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA Justin S. Golub – Columbia University, New York, NY, USA Joan G. Hewitt – Project TALK, Inc., Encinitas, CA, USA Daniel Jethanamest – NYU School of Medicine, New York, NY, USA Matthew Kircher – Loyola University Medical Center, Maywood, IL, USA Ruwan Kiringoda – Sutter Health, Fremont, CA, USA Robert F. Labadie – Vanderbilt University Medical Center, Nashville, TN, USA Teddy McRackan – Medical University of South Carolina, Charleston, SC, USA Aaron C. Moberly – The Ohio State University, Columbus, OH, USA Julie K. Purdy – Rady Children’s Hospital, San Diego, CA, USA Alejandro Rivas – Vanderbilt University, Nashville, TN, USA The Science of Hearing and Balance
Ksenia Aaron - Stanford University, Palo Alto, CA, USA Daniela Carvalho - UCSD Pediatric耳鼻喉科，San Diego, CA, USA Wade W. Chien -美国国立卫生研究院，Bethesda, MD, USA Maura K. Cosetti -纽约西奈山眼耳医院，New York, NY, USA Justin S. Golub -哥伦比亚大学，New York, NY, USA Joan G. Hewitt - Project TALK, Inc.， CA, Encinitas, USA Daniel Jethanamest - NYU School of Medicine, New York, NY，美国Matthew Kircher - Loyola大学医学中心，伊利诺斯州梅伍德，美国Ruwan Kiringoda -萨特健康，加利福尼亚州弗里蒙特，美国Robert F. Labadie -范德比尔特大学医学中心，田纳西州纳什维尔Teddy McRackan -南卡罗来纳州查尔斯顿医科大学，美国俄亥俄州哥伦布市俄亥俄州立大学Julie K. Purdy -雷迪儿童医院，加利福尼亚州圣地亚哥，美国Alejandro Rivas -范德比尔特大学，田纳西州纳什维尔，美国听力与平衡科学
{"title":"Contents Vol. 24, 2019","authors":"Joan G. Hewitt, R. Labadie, A. Moberly, J. Purdy, I. Schrauwen, Kareem O. Tawfik, D. Cotanche","doi":"10.1159/000505674","DOIUrl":"https://doi.org/10.1159/000505674","url":null,"abstract":"Ksenia Aaron – Stanford University, Palo Alto, CA, USA Daniela Carvalho – UCSD Pediatric Otolaryngology, San Diego, CA, USA Wade W. Chien – National Institutes of Health, Bethesda, MD, USA Maura K. Cosetti – New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA Justin S. Golub – Columbia University, New York, NY, USA Joan G. Hewitt – Project TALK, Inc., Encinitas, CA, USA Daniel Jethanamest – NYU School of Medicine, New York, NY, USA Matthew Kircher – Loyola University Medical Center, Maywood, IL, USA Ruwan Kiringoda – Sutter Health, Fremont, CA, USA Robert F. Labadie – Vanderbilt University Medical Center, Nashville, TN, USA Teddy McRackan – Medical University of South Carolina, Charleston, SC, USA Aaron C. Moberly – The Ohio State University, Columbus, OH, USA Julie K. Purdy – Rady Children’s Hospital, San Diego, CA, USA Alejandro Rivas – Vanderbilt University, Nashville, TN, USA The Science of Hearing and Balance","PeriodicalId":8624,"journal":{"name":"Audiology and Neurotology","volume":"31 1","pages":"I - VI"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75025800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Á. Ramos Macías, Á. Ramos de Miguel, Isaura Rodriguez Montesdeoca, Silvia Borkoski Barreiro, J. C. Falcón González
Introduction: Bilateral vestibulopathy is an important cause of imbalance that is misdiagnosed. The clinical management of patients with bilateral vestibular loss remains difficult as there is no clear evidence for an effective treatment. In this paper, we try to analyze the effect of chronic electrical stimulation and adaptation to electrical stimulation of the vestibular system in humans when stimulating the otolith organ with a constant pulse train to mitigate imbalance due to bilateral vestibular dysfunction (BVD). Methods: We included 2 patients in our study with BVD according to Criteria Consensus of the Classification Committee of the Bárány Society. Both cases were implanted by using a full-band straight electrode to stimulate the otoliths organs and simultaneously for the cochlear stimulation we use a perimodiolar electrode. Results: In both cases Vestibular and clinical test (video head impulse test, videonistagmography cervical vestibular evoked myogenic potentials, cVEMP and oVEMP), subjective visual vertical test, computerized dynamic posturography, dynamic gait index, Time UP and Go test and dizziness handicap index) were performed. Posture and gait metrics reveal important improvement if compare with preoperartive situation. Oscillopsia, unsteadiness, independence and quality of life improved to almost normal situation. Discussion/Conclusion: Prosthetic implantation of the otolith organ in humans is technically feasible. Electrical stimulation might have potential effects on balance and this is stable after 1 year follow-up. This research provides new possibilities for the development of vestibular implants to improve gravito-inertial acceleration sensation, in this case by the otoliths stimulation.
导读:双侧前庭病变是导致失衡的重要原因，常被误诊。由于没有明确的有效治疗证据，双侧前庭功能丧失患者的临床管理仍然很困难。在本文中，我们试图分析慢性电刺激和适应电刺激对人类前庭系统的影响，以恒定的脉冲序列刺激耳石器官，以减轻双侧前庭功能障碍(BVD)引起的不平衡。方法:根据Bárány学会分类委员会的标准共识，我们纳入了2例BVD患者。两例植入术均采用全带直电极刺激耳石器官，同时采用磨牙周围电极刺激耳蜗。结果:两例患者均进行了前庭和临床测试(视频头脉冲测试、视频颈前诱发肌电位、cVEMP和oVEMP)、主观视觉垂直测试、计算机动态体位摄影、动态步态指数、Time UP and Go测试和头晕障碍指数)。与术前相比，姿势和步态指标显示了重要的改善。示波器、不稳定、独立和生活质量改善到几乎正常的情况。讨论/结论:人工耳石植入术在技术上是可行的。电刺激可能对平衡有潜在的影响，经过1年的随访，这种影响是稳定的。这项研究为前庭植入物的发展提供了新的可能性，以改善重力惯性加速度感觉，在这种情况下，通过耳石刺激。
{"title":"Chronic Electrical Stimulation of the Otolith Organ: Preliminary Results in Humans with Bilateral Vestibulopathy and Sensorineural Hearing Loss","authors":"Á. Ramos Macías, Á. Ramos de Miguel, Isaura Rodriguez Montesdeoca, Silvia Borkoski Barreiro, J. C. Falcón González","doi":"10.1159/000503600","DOIUrl":"https://doi.org/10.1159/000503600","url":null,"abstract":"Introduction: Bilateral vestibulopathy is an important cause of imbalance that is misdiagnosed. The clinical management of patients with bilateral vestibular loss remains difficult as there is no clear evidence for an effective treatment. In this paper, we try to analyze the effect of chronic electrical stimulation and adaptation to electrical stimulation of the vestibular system in humans when stimulating the otolith organ with a constant pulse train to mitigate imbalance due to bilateral vestibular dysfunction (BVD). Methods: We included 2 patients in our study with BVD according to Criteria Consensus of the Classification Committee of the Bárány Society. Both cases were implanted by using a full-band straight electrode to stimulate the otoliths organs and simultaneously for the cochlear stimulation we use a perimodiolar electrode. Results: In both cases Vestibular and clinical test (video head impulse test, videonistagmography cervical vestibular evoked myogenic potentials, cVEMP and oVEMP), subjective visual vertical test, computerized dynamic posturography, dynamic gait index, Time UP and Go test and dizziness handicap index) were performed. Posture and gait metrics reveal important improvement if compare with preoperartive situation. Oscillopsia, unsteadiness, independence and quality of life improved to almost normal situation. Discussion/Conclusion: Prosthetic implantation of the otolith organ in humans is technically feasible. Electrical stimulation might have potential effects on balance and this is stable after 1 year follow-up. This research provides new possibilities for the development of vestibular implants to improve gravito-inertial acceleration sensation, in this case by the otoliths stimulation.","PeriodicalId":8624,"journal":{"name":"Audiology and Neurotology","volume":"15 1","pages":"79 - 90"},"PeriodicalIF":0.0,"publicationDate":"2019-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87441611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To evaluate resonance frequency (RF) values via dehydration effects in the inner ear caused by the glycerol test, which is used as a diagnostic method for Ménière’s disease (MD). Methods: Twenty adult patients with unilateral MD were included in the study. Before, and then at 1, 2, and 3 h after administration of glycerol (1 g/kg), pure-tone hearing levels (125–8,000 kHz) and multifrequency tympanometry tests were performed. As a control, the RF values of the ears of 25 healthy subjects (i.e., 50 ears) were compared to the affected and unaffected ears in the 20 MD patients. Results: There was a significant difference between the RF values of affected and healthy ears before glycerol administration (p = 0.047). The RF values before and after glycerol administration into affected ears were compared. The average RF values decreased significantly from 748.0 ± 402.1 to 808.0 ± 410.1 Hz at 1 h after glycerol intake, and this value increased during the subsequent hours. There were no statistically significant differences between the pure-tone levels before and 1 h after glycerol administration, but a significant decrease was observed at 3 h. Conclusion: We suggest that MD has different inner-ear dynamics and normal RF values when compared to healthy ears. Furthermore, decreased inner ear pressure causes reduction of the mass effect and a stiffening of the annular ligament. We conclude that pre- and post-RF tests should be added to the test battery for diagnosis of MD.
{"title":"Effects of Glycerol Test on Resonance Frequency in Patients with Ménière’s Disease","authors":"I. Oz, E. Hızal, O. Çam, L. Ozluoglu","doi":"10.1159/000503845","DOIUrl":"https://doi.org/10.1159/000503845","url":null,"abstract":"Objective: To evaluate resonance frequency (RF) values via dehydration effects in the inner ear caused by the glycerol test, which is used as a diagnostic method for Ménière’s disease (MD). Methods: Twenty adult patients with unilateral MD were included in the study. Before, and then at 1, 2, and 3 h after administration of glycerol (1 g/kg), pure-tone hearing levels (125–8,000 kHz) and multifrequency tympanometry tests were performed. As a control, the RF values of the ears of 25 healthy subjects (i.e., 50 ears) were compared to the affected and unaffected ears in the 20 MD patients. Results: There was a significant difference between the RF values of affected and healthy ears before glycerol administration (p = 0.047). The RF values before and after glycerol administration into affected ears were compared. The average RF values decreased significantly from 748.0 ± 402.1 to 808.0 ± 410.1 Hz at 1 h after glycerol intake, and this value increased during the subsequent hours. There were no statistically significant differences between the pure-tone levels before and 1 h after glycerol administration, but a significant decrease was observed at 3 h. Conclusion: We suggest that MD has different inner-ear dynamics and normal RF values when compared to healthy ears. Furthermore, decreased inner ear pressure causes reduction of the mass effect and a stiffening of the annular ligament. We conclude that pre- and post-RF tests should be added to the test battery for diagnosis of MD.","PeriodicalId":8624,"journal":{"name":"Audiology and Neurotology","volume":"52 1","pages":"285 - 292"},"PeriodicalIF":0.0,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87513419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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