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Diagnostic efficacy of combining diffusion-weighted magnetic resonance imaging with serum Mucin 1, Mucin 13, and Mucin 16 in distinguishing borderline from malignant epithelial ovarian tumors 将弥散加权磁共振成像与血清粘蛋白 1、粘蛋白 13 和粘蛋白 16 相结合,对区分边缘性和恶性上皮性卵巢肿瘤的诊断效果。
IF 1.4 4区 医学 Q4 ONCOLOGY Pub Date : 2024-01-14 DOI: 10.1111/ajco.14045
Xiao-Ting Wen, Hai-Feng Qiu, Ling-Ling Ying, Min Huang, Yun-Zhou Xiao, Chen-Chen Fan

Aims

To enhance ovarian tumor diagnosis beyond conventional methods, this study explored combining diffusion-weighted magnetic resonance imaging (DWI-MRI) and serum biomarkers (Mucin 1 [MUC1], MUC13, and MUC16) for distinguishing borderline from malignant epithelial ovarian tumors.

Methods

A total of 126 patients, including 71 diagnosed with borderline (BEOTs) and 55 with malignant epithelial ovarian tumors (MEOTs), underwent preoperative DWI-MRI. Region of interest (ROI) was manually drawn along the solid component's boundary of the largest tumor, focusing on areas with potentially the lowest apparent diffusion coefficient (ADC). For entirely cystic tumors, a free-form ROI enclosed the maximum number of septa while targeting the lowest ADC. Serum biomarkers were determined using enzyme-linked immunosorbent assay.

Results

Basic morphological traits proved inadequate for malignancy diagnosis, warranting this investigation. BEOTs had an ADC mean of (1.670 ± 0.250) × 103 mm2/s, while MEOTs had a lower ADC mean of (1.332 ± 0.481) × 103 mm2/s, with a sensitivity of 63.6% and specificity of 90.1%. Median MUC1 (167.0 U/mL vs. 87.3 U/mL), MUC13 (12.44 ng/mL vs. 7.77 ng/mL), and MUC16 (180.6 U/mL vs. 36.1 U/mL) levels were higher in MEOTs patients. The biomarker performance was: MUC1, sensitivity 50.9%, specificity 100%; MUC13, sensitivity 56.4%, specificity 78.9%; MUC16, sensitivity 83.64%, specificity 100%. Combining serum biomarkers and ADC mean resulted in a sensitivity of 96.4% and specificity of 100%.

Conclusion

The integration of DWI-MRI with serum biomarkers (MUC1, MUC13, and MUC16) achieves exceptional diagnostic accuracy, offering a powerful tool for the precise differentiation between borderline and malignant epithelial ovarian tumors.

目的:为了超越传统方法提高卵巢肿瘤诊断水平,本研究探讨了结合弥散加权磁共振成像(DWI-MRI)和血清生物标志物(粘蛋白1 [MUC1]、MUC13和MUC16)区分边缘性卵巢肿瘤和恶性上皮性卵巢肿瘤的方法:共有126名患者接受了术前DWI-MRI检查,其中包括71名被诊断为边缘性卵巢肿瘤(BEOTs)和55名恶性上皮性卵巢肿瘤(MEOTs)患者。沿着最大肿瘤的实体部分边界手工绘制感兴趣区(ROI),重点关注表观扩散系数(ADC)可能最低的区域。对于完全囊性的肿瘤,自由形式的 ROI 将最大数量的隔膜包围起来,同时以最低 ADC 为目标。使用酶联免疫吸附法测定血清生物标志物:基本形态特征不足以进行恶性肿瘤诊断,因此有必要进行这项研究。BEOT的ADC平均值为(1.670 ± 0.250)×103 mm2 /s,而MEOT的ADC平均值较低,为(1.332 ± 0.481)×103 mm2 /s,敏感性为63.6%,特异性为90.1%。MEOTs患者的中位MUC1(167.0 U/mL对87.3 U/mL)、MUC13(12.44 ng/mL对7.77 ng/mL)和MUC16(180.6 U/mL对36.1 U/mL)水平较高。生物标志物的性能如下MUC1的灵敏度为50.9%,特异性为100%;MUC13的灵敏度为56.4%,特异性为78.9%;MUC16的灵敏度为83.64%,特异性为100%。结合血清生物标记物和 ADC 平均值,灵敏度为 96.4%,特异性为 100%:结论:将DWI-MRI与血清生物标记物(MUC1、MUC13和MUC16)相结合可获得极高的诊断准确性,是精确区分边缘性卵巢肿瘤和恶性上皮性卵巢肿瘤的有力工具。
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引用次数: 0
Response to COVID-19 vaccination in patients on cancer therapy: Analysis in a SARS-CoV-2-naïve population 癌症治疗患者对 COVID-19 疫苗接种的反应:对SARS-CoV-2免疫人群的分析
IF 1.9 4区 医学 Q4 ONCOLOGY Pub Date : 2024-01-14 DOI: 10.1111/ajco.14047
George Cavic, Andrew A. Almonte, Sarah M. Hicks, Teresa Neeman, Jo-Wai Wang, Sue Brew, Philip Y. Choi, Ian Cockburn, Elizabeth E. Gardiner, Desmond Yip, Aude M. Fahrer, Yada Kanjanapan

Background

Cancer patients have increased morbidity and mortality from COVID-19, but may respond poorly to vaccination. The Evaluation of COVID-19 Vaccination Efficacy and Rare Events in Solid Tumors (EVEREST) study, comparing seropositivity between cancer patients and healthy controls in a low SARS-CoV-2 community-transmission setting, allows determination of vaccine response with minimal interference from infection.

Methods

Solid tumor patients from The Canberra Hospital, Canberra, Australia, and healthy controls who received COVID-19 vaccination between March 2021 and January 2022 were included. Blood samples were collected at baseline, pre-second vaccine dose and at 1, 3 (primary endpoint), and 6 months post-second dose. SARS-CoV-2 anti-spike-RBD (S-RBD) and anti-nucleocapsid IgG antibodies were measured.

Results

Ninety-six solid tumor patients and 20 healthy controls were enrolled, with median age 62 years, and 60% were female. Participants received either AZD1222 (65%) or BNT162b2 (35%) COVID-19 vaccines. Seropositivity 3 months post vaccination was 87% (76/87) in patients and 100% (20/20) in controls (p = .12). Seropositivity was observed in 84% of patients on chemotherapy, 80% on immunotherapy, and 96% on targeted therapy (differences not satistically significant). Seropositivity in cancer patients increased from 40% (6/15) after first dose, to 95% (35/37) 1 month after second dose, then dropped to 87% (76/87) 3 months after second dose.

Conclusion

Most patients and all controls became seropositive after two vaccine doses. Antibody concentrations and seropositivity showed a decrease between 1 and 3 months post vaccination, highlighting need for booster vaccinations. SARS-CoV-2 infection amplifies S-RBD antibody responses; however, cannot be adequately identified using nucleocapsid serology. This underlines the value of our COVID-naïve population in studying vaccine immunogenicity.

背景:癌症患者因 COVID-19 而增加发病率和死亡率,但可能对疫苗接种反应不佳。COVID-19疫苗接种效果和实体瘤罕见事件评估(EVEREST)研究比较了在SARS-CoV-2社区低传播环境中癌症患者和健康对照组之间的血清阳性率,从而可以在感染干扰最小的情况下确定疫苗反应:方法:纳入澳大利亚堪培拉堪培拉医院的实体瘤患者和在 2021 年 3 月至 2022 年 1 月期间接种 COVID-19 疫苗的健康对照者。在基线、接种第二剂疫苗前、接种第二剂疫苗后的1个月、3个月(主要终点)和6个月采集血液样本。测定了 SARS-CoV-2 抗尖头-RBD(S-RBD)和抗核头 IgG 抗体:共招募了 96 名实体瘤患者和 20 名健康对照者,中位年龄为 62 岁,60% 为女性。参与者接种了AZD1222(65%)或BNT162b2(35%)COVID-19疫苗。接种后 3 个月,患者血清阳性率为 87%(76/87),对照组为 100% (20/20)(p = .12)。接受化疗的患者血清阳性率为 84%,接受免疫疗法的患者为 80%,接受靶向疗法的患者为 96%(差异无统计学意义)。癌症患者的血清阳性率从第一次用药后的40%(6/15)上升到第二次用药后1个月的95%(35/37),然后又下降到第二次用药后3个月的87%(76/87):结论:大多数患者和所有对照组在接种两剂疫苗后血清反应呈阳性。抗体浓度和血清阳性率在接种后 1 个月至 3 个月期间有所下降,这表明有必要加强接种。SARS-CoV-2 感染会增强 S-RBD 抗体反应,但核壳血清学无法充分识别。这凸显了我们的 COVID 未感染人群在研究疫苗免疫原性方面的价值。
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引用次数: 0
A multidimensional assessment of payback: Evaluating the impact of Breast Cancer Trials 回报的多维评估:评估乳腺癌试验的影响。
IF 1.9 4区 医学 Q4 ONCOLOGY Pub Date : 2024-01-04 DOI: 10.1111/ajco.14043
Ruth Knight, Belinda Luke, Renata Meuter, Kaitlin Peters, Kathleen Chell

Aim

This study evaluates the impact created by clinical trial investment and research undertaken by Breast Cancer Trials (BCT).

Methods

The approach involved using the Payback Framework, and included a review of BCT archival information, public health data, a questionnaire sent to BCT members, individual interviews with key informants, a focus group with members of the organization's Consumer Advisory Panel, and case studies of select BCT trials. The evaluation assessed the evidence against the Payback Framework criteria: informing policy and product development, knowledge production, the research system, health and health sector benefits, and broader economic benefits.

Results

Analysis using the Payback Framework revealed impact was created in each category and a range of positive outcomes were identified for various stakeholder groups. BCT is maximizing the impact of its research and contributing to a global pool of scientific knowledge by collaborating with over 100 institutions and 820 researchers, yet its benefits go beyond research contributions. Findings highlight strong financial returns from BCT's research program and that BCT has played an important role in enhancing the public perception of clinical trials by promoting participation in trials, educating and empowering participants, and communicating trial outcomes.

Conclusion

BCT's clinical trials have had a significant impact on the prevention, detection, treatment, and management of breast cancer. Measuring and reporting impact can be resource intensive but support BCT in remaining accountable to all those invested in the organization and in breast cancer clinical trials, evidencing the multiple dimensions of payback resulting from the organization's research.

目的:本研究评估了乳腺癌试验(BCT)进行的临床试验投资和研究产生的影响:方法:采用 "回报框架"(Payback Framework),包括对 BCT 档案信息、公共卫生数据、发给 BCT 成员的调查问卷、对主要信息提供者的个别访谈、与该组织消费者顾问小组成员的焦点小组,以及对 BCT 部分试验的案例研究进行审查。评估根据 "回报框架 "标准对证据进行了评估:为政策和产品开发提供信息、知识生产、研究系统、健康和卫生部门效益以及更广泛的经济效益:利用回报框架进行的分析表明,每个类别都产生了影响,并为不同利益相关者群体确定了一系列积极成果。BCT 通过与 100 多个机构和 820 名研究人员合作,最大限度地发挥了其研究的影响,并为全球科学知识库做出了贡献,但其效益并不局限于研究贡献。研究结果表明,BCT的研究项目带来了丰厚的经济回报,而且BCT通过促进试验参与、教育和增强参与者的能力以及宣传试验结果,在提高公众对临床试验的认识方面发挥了重要作用:BCT的临床试验对乳腺癌的预防、检测、治疗和管理产生了重大影响。衡量和报告影响可能会耗费大量资源,但这有助于 BCT 继续对所有投资于该组织和乳腺癌临床试验的人员负责,证明该组织的研究可以带来多方面的回报。
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引用次数: 0
Overdiagnosis and overtreatment of ground-glass nodule-like lung cancer 磨玻璃结节样肺癌的过度诊断和过度治疗。
IF 1.4 4区 医学 Q4 ONCOLOGY Pub Date : 2024-01-04 DOI: 10.1111/ajco.14042
Xinyu Liang, Chao Zhang, Xin Ye

Lung cancer has had one of the highest incidences and mortality in the world over the last few decades, which has aided in the promotion and popularization of screening for lung ground-glass nodules (GGNs). People have great psychological anxiety about GGN because of the chance that it will develop into lung cancer, which makes clinical treatment of GGN a generally excessive phenomenon. Overdiagnosis in screening has recently been mentioned in the literature. An important research emphasis of screening is how to reduce the incidence of overdiagnosis and overtreatment. This paper discusses from different aspects how to characterize the occurrence of overdiagnosis and overtreatment, how to reduce overdiagnosis and overtreatment, and future screening, follow-up, and treatment approaches.

过去几十年来,肺癌一直是世界上发病率和死亡率最高的疾病之一,这也促进了肺磨玻璃结节(GGN)筛查的推广和普及。由于 GGN 有可能发展为肺癌,人们对 GGN 产生了极大的心理焦虑,这使得临床上对 GGN 的治疗普遍存在过度现象。最近有文献提到筛查中的过度诊断。如何降低过度诊断和过度治疗的发生率是筛查的一个重要研究重点。本文从不同方面探讨了如何描述过度诊断和过度治疗的发生,如何减少过度诊断和过度治疗,以及未来的筛查、随访和治疗方法。
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引用次数: 0
Recommendations for the treatment and management of adult B-Cell acute lymphoblastic leukemia in Asia-Pacific: Outcomes from a pilot initiative 亚太地区成人 B 细胞急性淋巴细胞白血病治疗和管理建议:试点倡议的成果。
IF 1.9 4区 医学 Q4 ONCOLOGY Pub Date : 2023-12-26 DOI: 10.1111/ajco.14041
Zhentang Lao, Kwong Yok Lam, Yuk Man Carol Cheung, Chieh-Lin Teng, Vivek Radhakrishnan, Dinesh Bhurani, Bor-Sheng Ko, Yeow Tee Goh

The outcomes of adult B-cell acute lymphoblastic leukemia (ALL) remain poor. Recent advancements in the field of leukemia research show potential for improved patient care. However, the adoption of research findings into clinical practice is fraught with practice- and country-specific challenges. The continued addition of new findings warrants critical evaluation for the feasibility of incorporation into clinical practice. A uniform set of evidence-based guidelines can favorably assist physicians in making optimal clinical decisions. Such a resource may also serve as a reference point for strategic planning of initiatives aimed at addressing critical barriers in the optimal management of B-cell ALL. This initiative was undertaken to seek a collaborative perspective and understand the existing challenges. Concordance-based recommendations were outlined through a systematic discussion on various aspects of treatment and management of adult B-cell ALL. The outcomes and experiences gained from this exercise will serve as a foundation for future efforts encompassing the more granular aspects of the management of B-cell ALL across the Asia-Pacific region.

成人 B 细胞急性淋巴细胞白血病(ALL)的治疗效果仍然不佳。白血病研究领域的最新进展显示出改善患者护理的潜力。然而,将研究成果应用于临床实践却充满了因实践和国家而异的挑战。随着新研究成果的不断增加,有必要对其纳入临床实践的可行性进行严格评估。一套统一的循证指南可以帮助医生做出最佳临床决策。这种资源还可作为战略规划的参考点,旨在解决 B 细胞 ALL 优化管理中的关键障碍。该倡议旨在寻求合作视角并了解现有挑战。通过对成人 B 细胞 ALL 治疗和管理的各个方面进行系统讨论,提出了基于一致性的建议。从这项活动中获得的成果和经验将为今后亚太地区B细胞ALL管理的更细化方面的工作奠定基础。
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引用次数: 0
Prevalence and risk factors of chemotherapy-induced oral mucositis among adult cancer patients at the cancer unit of Mbarara Regional Referral Hospital 姆巴拉拉地区转诊医院(Mbarara Regional Referral Hospital)癌症科成年癌症患者化疗引发口腔黏膜炎的患病率和风险因素。
IF 1.9 4区 医学 Q4 ONCOLOGY Pub Date : 2023-12-26 DOI: 10.1111/ajco.14044
Fredrick Atwiine, Julius Kyomya, Esther C. Atukunda, John Isiiko, Tadele Mekuriya Yadesa

Background

Chemotherapy is a common treatment for cancer, but it is associated with adverse drug reactions like oral mucositis. This condition destroys basal cells in the oral mucosal layer, causing inflammation and ulceration. This can impact the patient's physical, emotional, and psychological well-being, affecting treatment outcomes and quality of life. This study aims to determine the prevalence, severity, and risk factors of chemotherapy-induced oral mucositis among adult cancer patients.

Methods

The study was a cross-sectional study conducted among adult cancer patients receiving chemotherapy at the cancer unit of Mbarara Regional Referral Hospital in southwestern Uganda. Data was collected through patient interviews, oral examinations, and patient chart reviews.

Results

Out of 268 patients, 115 (42.9%) experienced oral mucositis. Grade 2 oral mucositis was the most common (44.3%) followed by grade 1 (35.7%) and grade 3 (20.0%). Independent risk factors of chemotherapy-induced oral mucositis were female gender (Adjusted Odds Ratio (AOR) = 2.19, 95% confidence interval [CI]: 1.27–3.78; p-value = 0.005), poor oral hygiene (AOR = 3.70, 95% CI: 1.51–9.10; p-value = 0.04), and receiving chemotherapy containing an alkylating agent (AOR = 3.17, 95% CI: 1.63–6.19; p-value < 0.001).

Conclusion

The study found that two out of five chemotherapy patients developed oral mucositis, with nearly half being grade 2. The risk factors identified in our study were comparable to those reported in previous studies. Therefore, identification and assessment of cancer patients at high risk for chemotherapy-induced oral mucositis should be routinely done for proper and timely management.

背景:化疗是一种常见的癌症治疗方法,但与口腔黏膜炎等药物不良反应有关。这种情况会破坏口腔黏膜层的基底细胞,引起炎症和溃疡。这会影响患者的身体、情绪和心理健康,影响治疗效果和生活质量。本研究旨在确定化疗引起的口腔黏膜炎在成年癌症患者中的发病率、严重程度和风险因素:本研究是一项横断面研究,对象是在乌干达西南部姆巴拉拉地区转诊医院癌症科接受化疗的成年癌症患者。数据通过患者访谈、口腔检查和病历审查收集:在 268 名患者中,115 人(42.9%)出现了口腔黏膜炎。2级口腔黏膜炎最常见(44.3%),其次是1级(35.7%)和3级(20.0%)。化疗诱发口腔黏膜炎的独立风险因素是女性(调整后比值比 (AOR) = 2.19,95% 置信区间 [CI]:1.27-3.78;p 值 = 0.005)、口腔卫生差(AOR = 3.70,95% CI:1.51-9.10;p 值 = 0.04)以及接受含有烷化剂的化疗(AOR = 3.17,95% CI:1.63-6.19;p 值研究发现,每五名化疗患者中就有两名出现口腔黏膜炎,其中近一半为二级。我们的研究发现的风险因素与以往研究报告的风险因素相当。因此,应定期对化疗诱发口腔黏膜炎的高危癌症患者进行识别和评估,以便及时采取适当的治疗措施。
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引用次数: 0
8th International Conference on Biomedical Engineering and Pharmaceutical Sciences (ICBEPS2023) 第八届生物医学工程与制药科学国际会议(ICBEPS2023),2023 年 6 月 16-17 日。
IF 1.9 4区 医学 Q4 ONCOLOGY Pub Date : 2023-12-19 DOI: 10.1111/ajco.14036
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引用次数: 0
The impact of targeted nursing intervention on postoperative medication adherence, quality of life, and psychological flexibility of thyroid cancer patients 针对性护理干预对甲状腺癌患者术后服药依从性、生活质量及心理灵活性的影响
IF 1.4 4区 医学 Q4 ONCOLOGY Pub Date : 2023-12-07 DOI: 10.1111/ajco.14037
Xiaohong Xu, Li Zhou, Wen Qiu, Yifang Su

Objective

To explore the effect of targeted nursing intervention on postoperative medication adherence, quality of life, and psychological flexibility of patients with thyroid cancer (TC).

Methods

A total of 330 patients were randomly divided into a Control group and an Intervention group (cases in the Intervention group were given targeted nursing interventions and cases in the Control group were given routine health education), with 165 cases in each group. In the Intervention group, targeted dietary and psychological nursing interventions were conducted on TC patients, and the effects of targeted nursing interventions on the quality of life, medication adherence, and psychological flexibility were compared through the SF-36 Short Form Health Survey, Morisky Medication Adherence Scale and Psychological Resilience Scale with the Control group. Univariate analysis and multiple stepwise regression analysis were performed to analyze the influencing factors of psychological flexibility in patients after nursing intervention.

Results

The Intervention group patients, after nursing intervention, in terms of life quality, scores of social function, physical function, and mental function were all higher than those of the Control group. Note that, 160 patients in the Intervention group (96.97%) had better treatment scores, which was significantly higher than that in the Control group (84.24%). The scores of mental resilience in the Intervention group reached 67.82 ± 13.85, and the two items of resilience, control, and optimism were significantly improved compared with the Control group (p < 0.05). Factors that had greater impacts on the psychological flexibility of TC patients were: age, education, per capita monthly income, and family residence.

Conclusion

Targeted nursing intervention had positive promoting effects on postoperative medication adherence, quality of life, and psychological flexibility of TC patients.

目的:探讨针对性护理干预对甲状腺癌(TC)患者术后服药依从性、生活质量及心理灵活性的影响。方法:330例患者随机分为对照组和干预组(干预组给予针对性护理干预,对照组给予常规健康教育),每组165例。干预组对TC患者进行针对性饮食和心理护理干预,并通过SF-36健康问卷、Morisky药物依从性量表和心理弹性量表与对照组比较针对性护理干预对TC患者生活质量、药物依从性和心理弹性的影响。采用单因素分析和多元逐步回归分析对护理干预后患者心理灵活性的影响因素进行分析。结果:干预组患者在护理干预后的生活质量、社会功能、身体功能、心理功能得分均高于对照组。值得注意的是,干预组有160例患者(96.97%)的治疗评分较好,显著高于对照组(84.24%)。干预组心理弹性得分为67.82±13.85分,与对照组相比,心理弹性、控制、乐观两项得分均显著提高(p)。结论:针对性护理干预对TC患者术后药物依从性、生活质量、心理弹性均有积极促进作用。
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引用次数: 0
Utility of survivorship care plans: A mixed-method study exploring general practitioners’ and cancer specialists’ views 幸存者护理计划的效用:探索全科医生和癌症专科医生观点的混合方法研究。
IF 1.9 4区 医学 Q4 ONCOLOGY Pub Date : 2023-12-05 DOI: 10.1111/ajco.14038
Sim Yee Tan, Haryana M. Dhillon, Channel Mak, Roger Liang, Kim Kerin-Ayres, Kylie Vuong, Ashanya Malalasekera, Janette L. Vardy

Purpose

Survivorship care plans (SCP) are recommended as integral to survivorship care but are not routinely provided in many centers. We explore whether SCP from the Sydney Cancer Survivorship Centre (SCSC) clinic was received by general practitioners (GP) and cancer specialists, and their views on SCP.

Methods

A mixed-method study comprising a quality assurance audit, a questionnaire of GP practices and GP, and semi-structured interviews of cancer specialists who referred patients to the SCSC clinic between 2019–2020. Descriptive statistics were used for quantitative data and content analysis for qualitative data.

Results

The audit found 153/190 (80.5%) SCSC attendees had SCP uploaded to hospital medical records. The response rate from GP practices was 41%; among the 55 responding practices, 38 (69%) did not receive the SCP. The response rate from GP was 19%; among the 29 responding GP, 25 (86%) indicated the SCP was worthwhile, especially follow-up plans and multidisciplinary team recommendations. Analysis of 14 cancer specialist interviews identified themes of 1) awareness of SCP; 2) access: SCP difficult to locate; 3) process: access and distribution require improvement; 4) systemic issues; 5) content and layout: more concise and better readability required; 6) value: mainly for GP and survivors; 7) use of SCP: limited; 8) recommendations: improve delivery process, enhance layout/content, more stakeholder input, more tailored information.

Conclusion

Although response rates from GP were low, those responding perceived SCP to be useful. Cancer specialists believed SCP were more valuable for GP and survivors. Process issues, especially SCP delivery, need to be improved.

目的:幸存者关怀计划(SCP)被推荐为幸存者关怀不可或缺的一部分,但在许多中心并未常规提供。我们探讨了全科医生(GP)和癌症专家是否接受悉尼癌症幸存者中心(SSCSC)诊所提供的幸存者护理计划,以及他们对幸存者护理计划的看法:这是一项混合方法研究,包括质量保证审计、全科医生诊所和全科医生问卷调查,以及对2019-2020年间将患者转诊至SCSC诊所的癌症专家进行的半结构化访谈。定量数据采用描述性统计,定性数据采用内容分析:审计发现,153/190(80.5%)名 SCSC 患者已将 SCP 上传到医院病历中。全科医生诊所的回复率为41%;在55家回复的诊所中,有38家(69%)没有收到SCP。全科医生的回复率为 19%;在 29 位回复的全科医生中,25 位(86%)表示 SCP 是值得的,尤其是后续计划和多学科团队建议。通过对 14 位癌症专家的访谈进行分析,确定了以下主题:1)对 SCP 的认识;2)获取途径:3)过程:获取和分发需要改进;4)系统性问题;5)内容和布局:需要更简洁、可读性更好;6)价值:主要针对全科医生和幸存者;7)SCP 的使用:有限;8)建议:改进提供过程、加强布局/内容、更多利益相关者的投入、更多定制信息:尽管全科医生的回复率较低,但回复者认为 SCP 是有用的。癌症专家认为,SCP 对全科医生和幸存者更有价值。流程问题,尤其是 SCP 的提供,需要改进。
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引用次数: 0
Participation in oral health screening among cancer survivors 参与癌症幸存者的口腔健康检查。
IF 1.9 4区 医学 Q4 ONCOLOGY Pub Date : 2023-11-23 DOI: 10.1111/ajco.14035
In Cheol Hwang, Hong Yup Ahn
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引用次数: 0
期刊
Asia-Pacific journal of clinical oncology
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