首页 > 最新文献

Bali Journal of Anesthesiology最新文献

英文 中文
A new formula for selecting the size of cuffed endotracheal tubes in pediatric patients 选择儿科患者气管插管尺寸的新公式
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_118_23
Ji Kwon, Ki Lee, Sang Lee, Yong Kim, Sung Shin
Background: Choosing an appropriate endotracheal tube size during the first attempt is crucial for avoiding unnecessary reintubation. Previous studies on endotracheal tube size in children focused on uncuffed tubes. Following recent studies on pediatric airway anatomy, cuffed endotracheal tubes are increasingly utilized in children. The objective of our study was to develop a new formula for selecting the correctly sized cuffed endotracheal tube for pediatric patients. Materials and Methods: We examined the electronic anesthetic records of 465 pediatric patients who received elective ophthalmic surgery between January 2011 and December 2018. Multiple linear regression was used to identify potential predictors of cuffed endotracheal size among age, weight, height, body mass index, and the presence of underweight, overweight, and obesity. We used repeated-measures ANOVA to assess the difference between the actual and calculated sizes of the endotracheal tube. Results: The derived formula is as follows: Predicted endotracheal tube size (mm) = 3.7 + 0.1 × age (years) + 0.02 × weight (kg) + 0.1 × presence of overweight (0: negative, 1: positive). The coefficient of determination (R2) for the total population was 0.685 and was higher in the overweight group (R2 = 0.763). When compared with the three conventional age-based formulas (Cole’s, Khine’s, and Duracher’s formula), the difference between the actual endotracheal tube size and the endotracheal tube size calculated using Duracher’s formula was the smallest. Conclusions: In choosing the appropriate size of a cuffed endotracheal tube in children, age and body size should be considered.
背景:首次尝试时选择合适的气管导管尺寸对于避免不必要的再次插管至关重要。以往关于儿童气管导管尺寸的研究主要集中在无袖带气管导管上。随着最近对儿童气道解剖学的研究,带袖带的气管导管在儿童中的应用越来越广泛。我们的研究目的是为儿童患者选择正确尺寸的带袖带气管导管制定新的公式。材料和方法:我们检查了 2011 年 1 月至 2018 年 12 月期间接受眼科择期手术的 465 名儿科患者的电子麻醉记录。我们使用多元线性回归在年龄、体重、身高、体重指数以及是否存在体重不足、超重和肥胖中找出袖带气管大小的潜在预测因素。我们使用重复测量方差分析来评估气管导管实际尺寸与计算尺寸之间的差异。结果如下得出的公式如下预测气管导管尺寸(毫米)= 3.7 + 0.1 × 年龄(岁)+ 0.02 × 体重(千克)+ 0.1 × 是否超重(0:负值,1:正值)。总人口的决定系数(R2)为 0.685,超重组的决定系数更高(R2 = 0.763)。与三种基于年龄的传统公式(Cole 公式、Khine 公式和 Duracher 公式)相比,实际气管导管尺寸与使用 Duracher 公式计算出的气管导管尺寸之间的差异最小。结论在为儿童选择合适的袖带式气管导管尺寸时,应考虑年龄和体型。
{"title":"A new formula for selecting the size of cuffed endotracheal tubes in pediatric patients","authors":"Ji Kwon, Ki Lee, Sang Lee, Yong Kim, Sung Shin","doi":"10.4103/bjoa.bjoa_118_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_118_23","url":null,"abstract":"Background: Choosing an appropriate endotracheal tube size during the first attempt is crucial for avoiding unnecessary reintubation. Previous studies on endotracheal tube size in children focused on uncuffed tubes. Following recent studies on pediatric airway anatomy, cuffed endotracheal tubes are increasingly utilized in children. The objective of our study was to develop a new formula for selecting the correctly sized cuffed endotracheal tube for pediatric patients. Materials and Methods: We examined the electronic anesthetic records of 465 pediatric patients who received elective ophthalmic surgery between January 2011 and December 2018. Multiple linear regression was used to identify potential predictors of cuffed endotracheal size among age, weight, height, body mass index, and the presence of underweight, overweight, and obesity. We used repeated-measures ANOVA to assess the difference between the actual and calculated sizes of the endotracheal tube. Results: The derived formula is as follows: Predicted endotracheal tube size (mm) = 3.7 + 0.1 × age (years) + 0.02 × weight (kg) + 0.1 × presence of overweight (0: negative, 1: positive). The coefficient of determination (R2) for the total population was 0.685 and was higher in the overweight group (R2 = 0.763). When compared with the three conventional age-based formulas (Cole’s, Khine’s, and Duracher’s formula), the difference between the actual endotracheal tube size and the endotracheal tube size calculated using Duracher’s formula was the smallest. Conclusions: In choosing the appropriate size of a cuffed endotracheal tube in children, age and body size should be considered.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"114 1","pages":"141 - 144"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of health workers’ anxiety levels in coronavirus disease and regular intensive care unit Saiful Anwar Hospital Malang: A cross-sectional study 冠状病毒病和常规重症监护室医务人员焦虑水平的比较 赛福尔-安瓦尔医院(玛琅):横断面研究
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_149_23
Arie Fatoni, Maghfira Azizah, Ratri Istiqomah
Background: On a regional and global level, the prevalence of coronavirus disease (COVID-19) cases is rising daily, splitting intensive care units (ICUs) into COVID-19 ICUs and regular ICUs during the COVID-19 pandemic. Numerous studies have revealed that COVID-19 ICU health personnel had higher levels of anxiety than those in the regular ICU. This study aimed to compare the levels of anxiety among medical personnel in the regular ICU and the COVID-19 ICU. Materials and Methods: This is a population-based observational study. All healthcare workers working in COVID-19 and regular ICU at our institution were included in this study. The Generalized Anxiety Disorder-7 (GAD-7) questionnaire was used to measure the level of anxiety. Mann–Whitney test was used to compare the anxiety level of participants in both groups. Results: Of the 108 participants who filled out the questionnaire, there were 99 eligible subjects for further analysis. The mean GAD-7 score for COVID-19 ICU health professionals was higher (3.87 ± 4.18) than for regular ICU (1.87 ± 2.38), causing significant differences between the two groups (P = 0.005). Among all observed variables, a significant difference of anxiety levels between groups were found in age (P = 0.032) and education (P = 0.036) variables.. Conclusion: The anxiety levels among health workers in the COVID-19 ICU were significantly higher compared to those in the regular ICU setting.
背景:从地区和全球层面来看,冠状病毒病(COVID-19)病例的流行率每天都在上升,在 COVID-19 大流行期间,重症监护病房(ICU)被分为 COVID-19 ICU 和普通 ICU。大量研究表明,COVID-19 ICU 医护人员的焦虑水平高于普通 ICU 医护人员。本研究旨在比较普通 ICU 和 COVID-19 ICU 医务人员的焦虑水平。材料和方法:这是一项基于人群的观察性研究。本研究纳入了我院所有在 COVID-19 和普通重症监护室工作的医护人员。采用广泛性焦虑症-7(GAD-7)问卷来测量焦虑程度。采用 Mann-Whitney 检验比较两组参与者的焦虑水平。结果在 108 位填写了问卷的参与者中,有 99 位符合进一步分析的条件。COVID-19 ICU 医护人员的 GAD-7 平均得分(3.87 ± 4.18)高于普通 ICU 医护人员(1.87 ± 2.38),两组之间存在显著差异(P = 0.005)。在所有观察到的变量中,年龄(P = 0.032)和教育程度(P = 0.036)变量的焦虑水平在组间存在显著差异。结论COVID-19重症监护室医护人员的焦虑水平明显高于普通重症监护室医护人员。
{"title":"Comparison of health workers’ anxiety levels in coronavirus disease and regular intensive care unit Saiful Anwar Hospital Malang: A cross-sectional study","authors":"Arie Fatoni, Maghfira Azizah, Ratri Istiqomah","doi":"10.4103/bjoa.bjoa_149_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_149_23","url":null,"abstract":"Background: On a regional and global level, the prevalence of coronavirus disease (COVID-19) cases is rising daily, splitting intensive care units (ICUs) into COVID-19 ICUs and regular ICUs during the COVID-19 pandemic. Numerous studies have revealed that COVID-19 ICU health personnel had higher levels of anxiety than those in the regular ICU. This study aimed to compare the levels of anxiety among medical personnel in the regular ICU and the COVID-19 ICU. Materials and Methods: This is a population-based observational study. All healthcare workers working in COVID-19 and regular ICU at our institution were included in this study. The Generalized Anxiety Disorder-7 (GAD-7) questionnaire was used to measure the level of anxiety. Mann–Whitney test was used to compare the anxiety level of participants in both groups. Results: Of the 108 participants who filled out the questionnaire, there were 99 eligible subjects for further analysis. The mean GAD-7 score for COVID-19 ICU health professionals was higher (3.87 ± 4.18) than for regular ICU (1.87 ± 2.38), causing significant differences between the two groups (P = 0.005). Among all observed variables, a significant difference of anxiety levels between groups were found in age (P = 0.032) and education (P = 0.036) variables.. Conclusion: The anxiety levels among health workers in the COVID-19 ICU were significantly higher compared to those in the regular ICU setting.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"28 1","pages":"154 - 159"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139366189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perfusion index as predictor of intraoperative hypotension following subarachnoid block in cesarean section: A prospective, observational study 灌注指数作为剖宫产术中蛛网膜下腔阻滞术后术中低血压的预测指标:前瞻性观察研究
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_161_23
Sandeep Singh, Gurpreeti Kaur, Richa Jain, Neeru Luthra, Namrata Sharma, Anju Grewal
Background: Perfusion index (PI) can be used to assess peripheral perfusion dynamics as it depicts the changes in peripheral vascular tone. Increased risk of fall in blood pressure following subarachnoid block (SAB) has been reported in pregnant patients with raised PI value due to their decreased peripheral vascular resistance. This study aimed to evaluate PI as a noninvasive tool for predicting incidence and severity of maternal hypotension following SAB in parturients undergoing lower segment cesarean section (LSCS). Materials and Methods: A prospective, observational study was conducted on 120 American Society of Anesthesiologists-II parturients undergoing LSCS under SAB. Noninvasive blood pressure, heart rate (HR), and PI were recorded at baseline and at 1-min interval till delivery of baby. Episodes of hypotension, bradycardia, total amount of vasopressor consumption, intraoperative nausea, vomiting (IONV), and APGAR scores were observed. Results: Receiver operator characteristics curve determined the optimal cutoff point for PI to predict intraoperative hypotension and IONV was 3.82 with a sensitivity of 79.07% and specificity of 72.73%. Incidence of hypotension in subjects with a higher baseline PI (≥3.82) was 79.1% compared with 20.9% with low baseline PI (<3.82). Amount of vasopressor used and incidence of IONV was significantly higher in subjects with high baseline PI (P < 0.001). Conclusions: There is a significant correlation between PI and SAB-induced hypotension in parturients undergoing LSCS. Pregnant patients with higher baseline PI (>3.82) are at a greater risk of developing hypotension.
背景:灌注指数(PI)可用于评估外周灌注动态,因为它描述了外周血管张力的变化。有报道称,蛛网膜下腔阻滞(SAB)后,由于外周血管阻力下降,PI 值升高的孕妇血压下降的风险增加。本研究旨在评估 PI,将其作为一种无创工具,用于预测接受下段剖宫产术(LSCS)的孕妇在蛛网膜下腔阻滞术(SAB)后产妇低血压的发生率和严重程度。材料和方法:对 120 名在 SAB 下接受 LSCS 的美国麻醉医师协会 II 级产妇进行了前瞻性观察研究。无创血压、心率(HR)和 PI 均在基线和婴儿娩出前每隔 1 分钟记录一次。观察低血压发作、心动过缓、血管加压素消耗总量、术中恶心、呕吐(IONV)和 APGAR 评分。结果受体运算特性曲线确定了预测术中低血压和 IONV 的最佳 PI 临界点为 3.82,灵敏度为 79.07%,特异度为 72.73%。基线 PI 较高(≥3.82)的受试者发生低血压的几率为 79.1%,而基线 PI 较低(3.82)的受试者发生低血压的几率为 20.9%,后者发生低血压的风险更大。
{"title":"Perfusion index as predictor of intraoperative hypotension following subarachnoid block in cesarean section: A prospective, observational study","authors":"Sandeep Singh, Gurpreeti Kaur, Richa Jain, Neeru Luthra, Namrata Sharma, Anju Grewal","doi":"10.4103/bjoa.bjoa_161_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_161_23","url":null,"abstract":"Background: Perfusion index (PI) can be used to assess peripheral perfusion dynamics as it depicts the changes in peripheral vascular tone. Increased risk of fall in blood pressure following subarachnoid block (SAB) has been reported in pregnant patients with raised PI value due to their decreased peripheral vascular resistance. This study aimed to evaluate PI as a noninvasive tool for predicting incidence and severity of maternal hypotension following SAB in parturients undergoing lower segment cesarean section (LSCS). Materials and Methods: A prospective, observational study was conducted on 120 American Society of Anesthesiologists-II parturients undergoing LSCS under SAB. Noninvasive blood pressure, heart rate (HR), and PI were recorded at baseline and at 1-min interval till delivery of baby. Episodes of hypotension, bradycardia, total amount of vasopressor consumption, intraoperative nausea, vomiting (IONV), and APGAR scores were observed. Results: Receiver operator characteristics curve determined the optimal cutoff point for PI to predict intraoperative hypotension and IONV was 3.82 with a sensitivity of 79.07% and specificity of 72.73%. Incidence of hypotension in subjects with a higher baseline PI (≥3.82) was 79.1% compared with 20.9% with low baseline PI (<3.82). Amount of vasopressor used and incidence of IONV was significantly higher in subjects with high baseline PI (P < 0.001). Conclusions: There is a significant correlation between PI and SAB-induced hypotension in parturients undergoing LSCS. Pregnant patients with higher baseline PI (>3.82) are at a greater risk of developing hypotension.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"28 1","pages":"160 - 164"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence in anesthesia and critical care (part 1): Current perspective in critical care setting 麻醉和重症监护中的人工智能(第一部分):重症监护环境中的当前视角
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_189_23
Marilaeta Cindryani
{"title":"Artificial intelligence in anesthesia and critical care (part 1): Current perspective in critical care setting","authors":"Marilaeta Cindryani","doi":"10.4103/bjoa.bjoa_189_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_189_23","url":null,"abstract":"","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"9 1","pages":"125 - 125"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139364780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selective Critically ill patients with tracheostomy are eligible for direct from intensive care unit sent home: Case series 选择性气管切开的重症患者可直接从重症监护室送回家:病例系列
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_90_23
D. Purwaamidjaja, Mayang Lestari, Asep Hendradiana, Bastian Lubis, Muhammad Thamrin
To reduce the risk of critically ill patients becoming unstable and needing readmission to the intensive care unit (ICU), patients are typically treated in the ward first following discharge from ICU. However, managing patients with advanced or terminal comorbidities or those requiring palliative care differs from general patients. Patients in this category can be discharged immediately to their homes with tracheostomy care and family education. This case series describes the cases and outcomes of patients with direct from ICU sent home (DISH) protocol. Twelve patients were immediately discharged from the ICU upon completion of treatment. Following the established standard operating procedure, they underwent DISH from the ICU. Early tracheostomy was performed in every patient (from day 1 to day 12th postintubation). All patients were safely discharged following the DISH procedure. According to the findings of this case series, DISH of critically ill patients with tracheostomy cannulas can be executed securely if the patient management method is firmly established. This technique must involve a good education process involving the ICU team, doctors, and family/companions.
为了降低危重病人病情不稳定而需要再次送入重症监护室(ICU)的风险,病人从重症监护室出院后通常先在病房接受治疗。然而,对晚期或末期合并症患者或需要姑息治疗的患者的管理与普通患者不同。这类患者可以通过气管造口护理和家属教育立即出院回家。本系列病例描述了采用直接从重症监护室送回家(DISH)方案的患者的病例和治疗效果。12 名患者在完成治疗后立即从重症监护室出院。按照既定的标准操作程序,他们在重症监护室接受了 DISH 治疗。每位患者都进行了早期气管切开术(插管后第 1 天至第 12 天)。所有患者都在 DISH 手术后安全出院。根据该系列病例的研究结果,如果患者管理方法得到牢固确立,就可以安全地对使用气管造口插管的重症患者实施 DISH。这项技术必须包含一个良好的教育过程,让重症监护室团队、医生和家属/陪护人员都参与其中。
{"title":"Selective Critically ill patients with tracheostomy are eligible for direct from intensive care unit sent home: Case series","authors":"D. Purwaamidjaja, Mayang Lestari, Asep Hendradiana, Bastian Lubis, Muhammad Thamrin","doi":"10.4103/bjoa.bjoa_90_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_90_23","url":null,"abstract":"To reduce the risk of critically ill patients becoming unstable and needing readmission to the intensive care unit (ICU), patients are typically treated in the ward first following discharge from ICU. However, managing patients with advanced or terminal comorbidities or those requiring palliative care differs from general patients. Patients in this category can be discharged immediately to their homes with tracheostomy care and family education. This case series describes the cases and outcomes of patients with direct from ICU sent home (DISH) protocol. Twelve patients were immediately discharged from the ICU upon completion of treatment. Following the established standard operating procedure, they underwent DISH from the ICU. Early tracheostomy was performed in every patient (from day 1 to day 12th postintubation). All patients were safely discharged following the DISH procedure. According to the findings of this case series, DISH of critically ill patients with tracheostomy cannulas can be executed securely if the patient management method is firmly established. This technique must involve a good education process involving the ICU team, doctors, and family/companions.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"4 1","pages":"183 - 187"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139364408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phenylephrine, ondansetron, or combination of both for prevention of intraoperative nausea and vomiting in patients undergoing lower segment cesarean section: A prospective, double-blind randomized control trial 苯肾上腺素、昂丹司琼或二者联合用于预防下段剖宫产术患者术中恶心和呕吐:前瞻性双盲随机对照试验
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_105_23
Vikram Bedi, Pratibha Yadav, B. Bairwa, Santosh Choudhary, Naveen Kumar, Gayatri Deshpande
Background: Intraoperative nausea and vomiting (IONV) are common complications in patients undergoing lower segment cesarean section (LSCS) under subarachnoid block. This study aimed to compare the combination of phenylephrine and ondansetron with ondansetron and phenylephrine alone in preventing IONV in patients undergoing LSCS under subarachnoid block. Materials and Methods: This prospective, double-blind, randomized, comparative study included 195 patients posted for elective LSCS under subarachnoid block. They were randomly allocated into three groups of 65 each. Group A received phenylephrine (25 mcg/min) and ondansetron 4 mg, group B received phenylephrine (25 mcg/min), and group C received only ondansetron 4 mg. Primary outcome measured was the incidence of IONV. Secondary outcomes measured were hemodynamic parameters, incidence of intraoperative hypotension, and vasopressor requirement. Categorical data were presented as numbers (proportion) and compared using the Chi-square test. Results: The proportion of subjects who experienced IONV was highest in group C (24.6%) compared with groups A (9.2%) and B (10.7%) (P = 0.025). The mean number of episodes of IONV was significantly lower in patients who received a combination of phenylephrine and ondansetron compared with phenylephrine or ondansetron (0.126 ± 0.42 vs. 0.107 ± 0.312 vs. 0.307 ± 0.58; P = 0.0233). The number of episodes of intraoperative hypotension was significantly high in group C (0.23 ± 0.49) compared with other groups (P = 0.041). Conclusion: Infusion of 25 mcg/min of phenylephrine with 4 mg ondansetron and infusion of 25 mcg/min of phenylephrine alone reduce the incidence of IONV in patients undergoing elective LSCS under subarachnoid block when compared with ondansetron alone.
背景:术中恶心和呕吐(IONV)是蛛网膜下腔阻滞下行剖宫产术(LSCS)患者常见的并发症。本研究旨在比较苯肾上腺素和昂丹司琼联合用药与昂丹司琼和苯肾上腺素单独用药在蛛网膜下腔阻滞下进行 LSCS 的患者中预防 IONV 的效果。材料与方法:这项前瞻性、双盲、随机、对比研究纳入了 195 名在蛛网膜下腔阻滞下接受择期 LSCS 的患者。他们被随机分为三组,每组 65 人。A 组接受苯肾上腺素(25 微克/分钟)和昂丹司琼 4 毫克,B 组接受苯肾上腺素(25 微克/分钟),C 组仅接受昂丹司琼 4 毫克。测量的主要结果是 IONV 发生率。次要测量结果为血液动力学参数、术中低血压发生率和血管加压剂需求量。分类数据以数字(比例)表示,并使用卡方检验进行比较。结果与 A 组(9.2%)和 B 组(10.7%)相比,C 组出现 IONV 的比例最高(24.6%)(P = 0.025)。与苯肾上腺素或昂丹司琼相比,接受苯肾上腺素和昂丹司琼联合疗法的患者发生 IONV 的平均次数明显降低(0.126 ± 0.42 vs. 0.107 ± 0.312 vs. 0.307 ± 0.58;P = 0.0233)。与其他组相比,C 组术中低血压发作次数明显较高(0.23 ± 0.49)(P = 0.041)。结论与单独使用昂丹司琼相比,在蛛网膜下腔阻滞下输注 25 微克/分钟的苯肾上腺素和 4 毫克昂丹司琼以及单独输注 25 微克/分钟的苯肾上腺素可降低择期 LSCS 患者的 IONV 发生率。
{"title":"Phenylephrine, ondansetron, or combination of both for prevention of intraoperative nausea and vomiting in patients undergoing lower segment cesarean section: A prospective, double-blind randomized control trial","authors":"Vikram Bedi, Pratibha Yadav, B. Bairwa, Santosh Choudhary, Naveen Kumar, Gayatri Deshpande","doi":"10.4103/bjoa.bjoa_105_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_105_23","url":null,"abstract":"Background: Intraoperative nausea and vomiting (IONV) are common complications in patients undergoing lower segment cesarean section (LSCS) under subarachnoid block. This study aimed to compare the combination of phenylephrine and ondansetron with ondansetron and phenylephrine alone in preventing IONV in patients undergoing LSCS under subarachnoid block. Materials and Methods: This prospective, double-blind, randomized, comparative study included 195 patients posted for elective LSCS under subarachnoid block. They were randomly allocated into three groups of 65 each. Group A received phenylephrine (25 mcg/min) and ondansetron 4 mg, group B received phenylephrine (25 mcg/min), and group C received only ondansetron 4 mg. Primary outcome measured was the incidence of IONV. Secondary outcomes measured were hemodynamic parameters, incidence of intraoperative hypotension, and vasopressor requirement. Categorical data were presented as numbers (proportion) and compared using the Chi-square test. Results: The proportion of subjects who experienced IONV was highest in group C (24.6%) compared with groups A (9.2%) and B (10.7%) (P = 0.025). The mean number of episodes of IONV was significantly lower in patients who received a combination of phenylephrine and ondansetron compared with phenylephrine or ondansetron (0.126 ± 0.42 vs. 0.107 ± 0.312 vs. 0.307 ± 0.58; P = 0.0233). The number of episodes of intraoperative hypotension was significantly high in group C (0.23 ± 0.49) compared with other groups (P = 0.041). Conclusion: Infusion of 25 mcg/min of phenylephrine with 4 mg ondansetron and infusion of 25 mcg/min of phenylephrine alone reduce the incidence of IONV in patients undergoing elective LSCS under subarachnoid block when compared with ondansetron alone.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"2 1","pages":"145 - 149"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139364616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparable pain scale, onset, and duration of anesthesia in sub-Thenon’s and peribulbar anesthesia in vitrectomy: A pilot study 在玻璃体切除术中,Thenon's 下麻醉和ibulbar 周围麻醉的疼痛程度、起始时间和麻醉持续时间具有可比性:试点研究
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_156_23
Ari Andayani, Luh Putu Dewi, Ariesanti Handayani, I. Widiana, I. Jayanegara, I. Widnyana
Introduction: Specific guidelines regarding the safest and most effective anesthetic procedure for patients undergoing pars plana vitrectomy have not been established. Regional anesthetic use has increased in recent years. Regional anesthetic techniques can be needle-based (retrobulbar and peribulbar) and cannula-based (sub-Thenon’s block). This research aimed to compare the efficacy of sub-Thenon’s anesthesia and peribulbar block in vitrectomy surgery. Materials and Methods: This study was a prospective randomized controlled single-blind pilot. Thirty subjects were divided equally into sub-Thenon’s and peribulbar groups. Subjects were randomized by permuted block randomization with a single-blind method. Eye drops of 1% tropicamide and 5% phenylephrine were used to achieve pupil dilation. Local anesthetic used was 0.5% propacaine hydrochloride. Sub-Thenon anesthesia was achieved by 2.5 mL llidocaine 2% and 2.5 mL bupivacaine, whereas peribulbar block by 4 mL lidocaine 2% and 4 mL of bupivacaine 0.5% injection. The observed outcome variables included the numerical rating scale (NRS) at trocar insertion, anesthetic onset, and anesthesia duration. Results: The NRS during trocar insertion under sub-Thenon’s compared with peribulbar was comparable (P = 0.28). The onset of sub-Thenon’s versus peribulbar anesthesia is 6 versus 10 min (P = 0.74). Duration of anesthesia under sub-Thenon’s versus peribulbar anesthesia was 73.3 ± 30 versus 68 ± 26 min (P = 0.32). The results of multivariate analysis showed there were no differences in pain scale on trocar insertion, the onset of anesthesia, and duration of anesthesia between sub-Thenon’s and peribulbar anesthesia after controlling for confounding variables. Conclusion: There are no differences in trocar insertion pain scale, onset, and duration of anesthesia between sub-Thenon’s anesthesia and peribulbar anesthesia.
导言:对于接受玻璃体旁切除术的患者来说,最安全、最有效的麻醉程序的具体指导方针尚未确立。近年来,区域麻醉的使用有所增加。区域麻醉技术有针式(球后和球周)和套管式(Thenon 下阻滞)两种。本研究旨在比较特农氏下麻醉和球周阻滞在玻璃体切除手术中的疗效。材料和方法:本研究为前瞻性随机对照单盲试验。30 名受试者被平均分为Thenon's 下组和眼周阻滞组。受试者以单盲法进行随机分组。使用 1%托吡卡胺和 5%苯肾上腺素滴眼液进行散瞳。局部麻醉剂为 0.5% 盐酸丙卡因。瞳孔下麻醉采用2.5毫升2%利多卡因和2.5毫升布比卡因,而周围阻滞则采用4毫升2%利多卡因和4毫升0.5%布比卡因。观察结果变量包括套管插入时的数字评分量表(NRS)、麻醉开始时间和麻醉持续时间。结果:在Thenon's下插入套管时的NRS与在ibulbar周围插入套管时的NRS相当(P = 0.28)。Thenon's下麻醉与周围麻醉的起始时间分别为6分钟和10分钟(P = 0.74)。Thenon's下麻醉与臂周麻醉的麻醉持续时间分别为73.3±30分钟与68±26分钟(P = 0.32)。多变量分析结果显示,在控制了混杂变量后,在插入套管时的疼痛量表、麻醉开始时间和麻醉持续时间方面,特农氏下麻醉与臂周麻醉没有差异。结论特农氏麻醉和臂周麻醉在套管插入疼痛量表、麻醉开始时间和麻醉持续时间方面没有差异。
{"title":"Comparable pain scale, onset, and duration of anesthesia in sub-Thenon’s and peribulbar anesthesia in vitrectomy: A pilot study","authors":"Ari Andayani, Luh Putu Dewi, Ariesanti Handayani, I. Widiana, I. Jayanegara, I. Widnyana","doi":"10.4103/bjoa.bjoa_156_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_156_23","url":null,"abstract":"Introduction: Specific guidelines regarding the safest and most effective anesthetic procedure for patients undergoing pars plana vitrectomy have not been established. Regional anesthetic use has increased in recent years. Regional anesthetic techniques can be needle-based (retrobulbar and peribulbar) and cannula-based (sub-Thenon’s block). This research aimed to compare the efficacy of sub-Thenon’s anesthesia and peribulbar block in vitrectomy surgery. Materials and Methods: This study was a prospective randomized controlled single-blind pilot. Thirty subjects were divided equally into sub-Thenon’s and peribulbar groups. Subjects were randomized by permuted block randomization with a single-blind method. Eye drops of 1% tropicamide and 5% phenylephrine were used to achieve pupil dilation. Local anesthetic used was 0.5% propacaine hydrochloride. Sub-Thenon anesthesia was achieved by 2.5 mL llidocaine 2% and 2.5 mL bupivacaine, whereas peribulbar block by 4 mL lidocaine 2% and 4 mL of bupivacaine 0.5% injection. The observed outcome variables included the numerical rating scale (NRS) at trocar insertion, anesthetic onset, and anesthesia duration. Results: The NRS during trocar insertion under sub-Thenon’s compared with peribulbar was comparable (P = 0.28). The onset of sub-Thenon’s versus peribulbar anesthesia is 6 versus 10 min (P = 0.74). Duration of anesthesia under sub-Thenon’s versus peribulbar anesthesia was 73.3 ± 30 versus 68 ± 26 min (P = 0.32). The results of multivariate analysis showed there were no differences in pain scale on trocar insertion, the onset of anesthesia, and duration of anesthesia between sub-Thenon’s and peribulbar anesthesia after controlling for confounding variables. Conclusion: There are no differences in trocar insertion pain scale, onset, and duration of anesthesia between sub-Thenon’s anesthesia and peribulbar anesthesia.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"59 1","pages":"165 - 169"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139366044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of augmented reality in learning lumbar spinal anatomy for training in labor epidural insertion: A pilot study 使用增强现实技术学习腰椎解剖,进行分娩硬膜外插入培训:试点研究
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_75_23
Wei Lau, J. Chan, C. Chan, Chin Tan, B. Sng
Background: Augmented reality (AR) has gained importance, complementing teaching and learning in medicine. However, there is limited use of AR in anesthesia. We aimed to explore the usefulness of AR in learning spinal anatomy relevant to neuraxial needle insertion training in labor epidural analgesia with feedback from trainers and learners. Materials and Methods: A pilot study was conducted from January to March 2022 at a local specialist maternity hospital. Computer tomography images were obtained from an epidural mannequin trainer, reconstructed, and uploaded to an AR program loaded onto an AR device. Anesthetists with varying experiences utilized the AR program to evaluate the AR experience, with pre- and postuser surveys conducted. Results: Thirty-one participants were recruited with a mean (standard deviation) of 7.9 (6.2) years of anesthesia experience. Twenty-five (80.6%) were aware of AR applications, but most (80.6%) had no prior experience with AR-based learning. Using the Likert scale (1 being strongly disagree and 5 being strongly agree), the postuser survey showed median scores of ≥4 in all questions on AR-based learning. The majority (92%) agreed that the AR software should include functions for obtaining clear visualization of anatomy, rotating 3D structures, changing magnification, and selecting specific parts to focus on. Feedback also highlighted the need for familiarization and flexibility with manipulating holographic images and haptic device links for task training. Conclusions: Our study showed potential for AR in facilitating anatomy learning related to training in labor epidural insertion. Improvements through program flexibility and haptic device link could enhance task training.
背景:增强现实技术(AR)在医学教学中发挥着重要作用。然而,AR 在麻醉领域的应用还很有限。我们旨在根据培训师和学员的反馈,探索 AR 在学习分娩硬膜外镇痛中神经针插入培训相关的脊柱解剖学方面的实用性。材料和方法:2022 年 1 月至 3 月,在当地一家专科妇产医院开展了一项试点研究。计算机断层扫描图像从硬膜外人体模型训练器中获取、重建并上传到 AR 设备上的 AR 程序中。具有不同经验的麻醉师利用AR程序对AR体验进行了评估,并进行了使用前和使用后调查。结果:共招募了 31 名参与者,平均(标准差)麻醉经验为 7.9(6.2)年。25人(80.6%)知道AR应用,但大多数人(80.6%)以前没有基于AR的学习经验。使用李克特量表(1 表示非常不同意,5 表示非常同意)进行的用户后期调查显示,在有关基于 AR 的学习的所有问题中,得分中位数均≥4。大多数人(92%)同意,AR 软件应包括获得清晰的可视化解剖结构、旋转三维结构、改变放大倍率和选择要关注的特定部位等功能。反馈意见还强调,需要熟悉并灵活操作全息图像和触觉设备链接,以便进行任务培训。结论:我们的研究显示了 AR 在促进与分娩硬膜外插入培训相关的解剖学习方面的潜力。通过程序灵活性和触觉设备链接进行改进,可加强任务培训。
{"title":"Use of augmented reality in learning lumbar spinal anatomy for training in labor epidural insertion: A pilot study","authors":"Wei Lau, J. Chan, C. Chan, Chin Tan, B. Sng","doi":"10.4103/bjoa.bjoa_75_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_75_23","url":null,"abstract":"Background: Augmented reality (AR) has gained importance, complementing teaching and learning in medicine. However, there is limited use of AR in anesthesia. We aimed to explore the usefulness of AR in learning spinal anatomy relevant to neuraxial needle insertion training in labor epidural analgesia with feedback from trainers and learners. Materials and Methods: A pilot study was conducted from January to March 2022 at a local specialist maternity hospital. Computer tomography images were obtained from an epidural mannequin trainer, reconstructed, and uploaded to an AR program loaded onto an AR device. Anesthetists with varying experiences utilized the AR program to evaluate the AR experience, with pre- and postuser surveys conducted. Results: Thirty-one participants were recruited with a mean (standard deviation) of 7.9 (6.2) years of anesthesia experience. Twenty-five (80.6%) were aware of AR applications, but most (80.6%) had no prior experience with AR-based learning. Using the Likert scale (1 being strongly disagree and 5 being strongly agree), the postuser survey showed median scores of ≥4 in all questions on AR-based learning. The majority (92%) agreed that the AR software should include functions for obtaining clear visualization of anatomy, rotating 3D structures, changing magnification, and selecting specific parts to focus on. Feedback also highlighted the need for familiarization and flexibility with manipulating holographic images and haptic device links for task training. Conclusions: Our study showed potential for AR in facilitating anatomy learning related to training in labor epidural insertion. Improvements through program flexibility and haptic device link could enhance task training.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"546 1","pages":"135 - 140"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139366185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low procalcitonin clearance correlates with mortality treated with culture-matched antibiotics in intensive care unit: A retrospective, observational study 低降钙素原清除率与重症监护病房使用培养匹配抗生素治疗的死亡率相关:一项回顾性观察研究
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_157_23
Fradita Yunus Guzasiah, Haizah Nurdin, Faisal Muchtar, Hisbullah Rum, A. Palinrungi
Background: Sepsis is a clinical syndrome with a high mortality rate which shows a direct relationship with the severity of the disease. Changes in procalcitonin levels in several studies are considered indicators of bacterial infection. The goal of this study was to prove that low procalcitonin clearance is a mortality predictor in sepsis patients who are given antibiotics in the intensive care unit. Materials and Methods: This was an analytic, observational, retrospective study, with a cross-sectional design. The study was conducted by taking medical record data of sepsis patients who were treated with culture-specific antibiotics and then collecting data on changes in procalcitonin levels on the first day and 72 h antibiotics administration per antibiotic-sensitivity results. Patients were grouped with procalcitonin clearance <70% and ≥70% and were associated with survive and mortality groups. Data were analyzed by chi-square test. Results: There were 116 sepsis patients with an average age of 48.92 years. Most of the patients were aged 18–65 years (86.2%), with male predominance (72.4%). In this study, we found 68 patients (58.6%) with procalcitonin clearance ≥70%, whereas 48 patients (41.4%) had procalcitonin clearance <70%. The 28-day mortality in patients with procalcitonin clearance <70% (66.7%) was higher than in patients with procalcitonin clearance ≥70% (47.1%). There was a significant relationship between procalcitonin clearance <70% and the 28-day mortality outcome in septic patients who were given antibiotics according to culture (P = 0.036). Conclusion: Low procalcitonin clearance was significantly associated with 28-day mortality outcome in septic patients. Further studies are needed to gain a better understanding of this matter.
背景:败血症是一种死亡率很高的临床综合征,与疾病的严重程度有直接关系。在多项研究中,降钙素原水平的变化被认为是细菌感染的指标。本研究的目的是证明低降钙素原清除率是在重症监护室接受抗生素治疗的败血症患者的死亡率预测指标。材料和方法:这是一项分析性、观察性、回顾性研究,采用横断面设计。研究通过采集接受培养特异性抗生素治疗的脓毒症患者的病历数据,然后根据抗生素药敏结果收集第一天和使用抗生素 72 小时后降钙素原水平的变化数据。将降钙素原清除率<70%和≥70%的患者分组,并与存活组和死亡组相关联。数据采用卡方检验进行分析。结果共有 116 名败血症患者,平均年龄为 48.92 岁。大多数患者年龄在 18-65 岁之间(86.2%),男性占多数(72.4%)。在这项研究中,我们发现 68 名患者(58.6%)的降钙素原清除率≥70%,而 48 名患者(41.4%)的降钙素原清除率<70%。降钙素原清除率<70%的患者(66.7%)的28天死亡率高于降钙素原清除率≥70%的患者(47.1%)。根据培养结果给予抗生素治疗的脓毒症患者的降钙素原清除率<70%与28天死亡率之间存在明显关系(P = 0.036)。结论低降钙素原清除率与脓毒症患者 28 天内的死亡率结果有显著相关性。要更好地了解这一问题,还需要进一步的研究。
{"title":"Low procalcitonin clearance correlates with mortality treated with culture-matched antibiotics in intensive care unit: A retrospective, observational study","authors":"Fradita Yunus Guzasiah, Haizah Nurdin, Faisal Muchtar, Hisbullah Rum, A. Palinrungi","doi":"10.4103/bjoa.bjoa_157_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_157_23","url":null,"abstract":"Background: Sepsis is a clinical syndrome with a high mortality rate which shows a direct relationship with the severity of the disease. Changes in procalcitonin levels in several studies are considered indicators of bacterial infection. The goal of this study was to prove that low procalcitonin clearance is a mortality predictor in sepsis patients who are given antibiotics in the intensive care unit. Materials and Methods: This was an analytic, observational, retrospective study, with a cross-sectional design. The study was conducted by taking medical record data of sepsis patients who were treated with culture-specific antibiotics and then collecting data on changes in procalcitonin levels on the first day and 72 h antibiotics administration per antibiotic-sensitivity results. Patients were grouped with procalcitonin clearance <70% and ≥70% and were associated with survive and mortality groups. Data were analyzed by chi-square test. Results: There were 116 sepsis patients with an average age of 48.92 years. Most of the patients were aged 18–65 years (86.2%), with male predominance (72.4%). In this study, we found 68 patients (58.6%) with procalcitonin clearance ≥70%, whereas 48 patients (41.4%) had procalcitonin clearance <70%. The 28-day mortality in patients with procalcitonin clearance <70% (66.7%) was higher than in patients with procalcitonin clearance ≥70% (47.1%). There was a significant relationship between procalcitonin clearance <70% and the 28-day mortality outcome in septic patients who were given antibiotics according to culture (P = 0.036). Conclusion: Low procalcitonin clearance was significantly associated with 28-day mortality outcome in septic patients. Further studies are needed to gain a better understanding of this matter.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"11 1","pages":"150 - 153"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139364586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxcarbazepine-induced syndrome of inappropriate antidiuretic hormone secretion in a trigeminal neuralgia: A case report 三叉神经痛患者奥卡西平诱发的抗利尿激素分泌失调综合征:病例报告
Q4 Nursing Pub Date : 2023-07-01 DOI: 10.4103/bjoa.bjoa_40_23
S. Mallikarjuna, Priyanka Gupta, Siddharth Chakraborty, Alok Padhee
Hyponatremia is the most common electrolyte abnormality encountered in neurosurgical practice. The pathophysiology for hyponatremia among neurosurgical patients is most commonly due to syndrome of inappropriate antidiuretic hormone secretion (SIADH). SIADH is the most common cause of euvolemic hyponatremia. There are various causes of SIADH ranging from drugs to malignancies. Among neurosurgical patients, it is described in subarachnoid hemorrhage, traumatic brain injury, pituitary surgeries, postoperatively after intracranial insult, and rarely in association with other intracerebral pathologies. The diagnostic criteria for SIADH include hypoosmolality, elevated urinary osmolality, euvolemia, and elevated urinary sodium which was present in our case. Our patient was diagnosed with trigeminal neuralgia due to CP angle epidermoid and was on T. Oxcarbazepine 300 mg daily since 6 months for the neuropathic pain. History and physical examination were unremarkable except for serum sodium of 118 mEq/L. Though the possibility of intracranial tumor may be the cause of SIADH, which is very rare due to the tumor location; hence, the possible explanation for the asymptomatic hyponatremia in this patient may be due to oxcarbazepine-induced SIADH. Here is a case report of SIADH due to oxcarbazepine and its perioperative management in a 24-year-old woman diagnosed with trigeminal neuralgia.
低钠血症是神经外科最常见的电解质异常。神经外科患者低钠血症的病理生理学最常见的原因是抗利尿激素分泌不当综合征(SIADH)。SIADH 是造成无水低钠血症的最常见原因。导致 SIADH 的原因多种多样,包括药物和恶性肿瘤。在神经外科患者中,蛛网膜下腔出血、创伤性脑损伤、垂体手术、颅内损伤术后都会出现 SIADH,而与其他脑内病变相关的情况则很少见。SIADH 的诊断标准包括低渗透压、尿渗透压升高、低容量血症和尿钠升高,而我们的病例就存在这些症状。我们的患者被诊断为 CP 角硬皮症引起的三叉神经痛,从 6 个月前开始每天服用奥卡西平 300 毫克治疗神经痛。除了血清钠为 118 mEq/L 外,病史和体格检查均无异常。虽然颅内肿瘤可能是导致 SIADH 的原因,但由于肿瘤的位置,这种情况非常罕见;因此,该患者无症状性低钠血症的可能原因是奥卡西平诱发的 SIADH。以下是一例奥卡西平所致 SIADH 的病例报告,以及一名被诊断为三叉神经痛的 24 岁女性的围手术期处理。
{"title":"Oxcarbazepine-induced syndrome of inappropriate antidiuretic hormone secretion in a trigeminal neuralgia: A case report","authors":"S. Mallikarjuna, Priyanka Gupta, Siddharth Chakraborty, Alok Padhee","doi":"10.4103/bjoa.bjoa_40_23","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_40_23","url":null,"abstract":"Hyponatremia is the most common electrolyte abnormality encountered in neurosurgical practice. The pathophysiology for hyponatremia among neurosurgical patients is most commonly due to syndrome of inappropriate antidiuretic hormone secretion (SIADH). SIADH is the most common cause of euvolemic hyponatremia. There are various causes of SIADH ranging from drugs to malignancies. Among neurosurgical patients, it is described in subarachnoid hemorrhage, traumatic brain injury, pituitary surgeries, postoperatively after intracranial insult, and rarely in association with other intracerebral pathologies. The diagnostic criteria for SIADH include hypoosmolality, elevated urinary osmolality, euvolemia, and elevated urinary sodium which was present in our case. Our patient was diagnosed with trigeminal neuralgia due to CP angle epidermoid and was on T. Oxcarbazepine 300 mg daily since 6 months for the neuropathic pain. History and physical examination were unremarkable except for serum sodium of 118 mEq/L. Though the possibility of intracranial tumor may be the cause of SIADH, which is very rare due to the tumor location; hence, the possible explanation for the asymptomatic hyponatremia in this patient may be due to oxcarbazepine-induced SIADH. Here is a case report of SIADH due to oxcarbazepine and its perioperative management in a 24-year-old woman diagnosed with trigeminal neuralgia.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"2 1","pages":"170 - 172"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Bali Journal of Anesthesiology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1