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Volume-controlled, pressure-controlled vs. pressure-controlled volume-guaranteed ventilations in improving respiratory dynamics during laparoscopic cholecystectomy: A prospective, randomized, comparative study 容量控制、压力控制与压力控制容量保证通气在腹腔镜胆囊切除术中改善呼吸动力学:一项前瞻性、随机、比较研究
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_254_22
Sukriti Chowdhury, Asim Maiti, S. Chattopadhyay, Debasish Bhar
Introduction: Pressure-controlled volume-guaranteed (PCV-VG) mode has the advantage of both volume-controlled (VCV) and pressure-controlled ventilation (PCV). Our objective is to compare gaseous exchange and lung dynamic compliance (Cdyn) after pneumoperitoneum and just before desufflation in VCV, PCV, and PCV-VG mode in laparoscopic cholecystectomy (LC). Materials and Methods: A total of 105 patients undergoing LC under general anesthesia were randomly distributed to group V (received VCV), group P (PCV), and group PV (PCV-VG) as mode of ventilation. Two arterial blood samples were taken for blood gas analysis: after the pneumoperitoneum (T1) and right before abdominal desufflation (T2). Arterial partial oxygen pressure (PaO2) and carbon dioxide (PaCO2) levels, oxygen saturation (SpO2) and end-tidal carbon dioxide were compared at these two points of time between the groups. Results: Cdyn was higher in group P (43.21 ± 4.4 mL/cmH2O) compared with group V (39.18 ± 3.2 mL/cmH2O) and PV (40.37 ± 2.45 mL/cmH2O) at T2 (P < 0.001). PaO2 was significantly higher (P < 0.001) in group P (197.50 ± 17.29 mm Hg) at T2 compared with group V (178.90 ± 23.7 mm Hg) and PV (183.47 ± 22.99 mm Hg). Furthermore, PaCO2 was also significantly higher in Group P (40.19 ± 2.92 mm Hg) compared with group V (32.57 ± 2.09 mm Hg) and group PV (34.14 ± 3.27 mm Hg). Conclusion: PaO2 and dynamic compliance are higher in pressure-controlled mode but, high PaCO2 in pressure-controlled mode indicates inadequate ventilation. Therefore, pressure controlled volume guaranteed mode can be considered as a favorable ventilation strategy during LC because dynamic compliance and PaO2 are higher than volume controlled ventilation and PaCO2 is significantly less than pressure controlled mode.
简介:压力控制容积保证(PCV-VG)模式具有容积控制(VCV)和压力控制通风(PCV)的优点。我们的目的是比较腹腔镜胆囊切除术(LC)中VCV、PCV和PCV-VG模式下气腹后和减压前的气体交换和肺动态顺应性(Cdyn)。材料和方法:将105例全麻下LC患者随机分为V组(接受VCV)、P组(PCV)和PV组(PCV-VG)作为通气模式。取两份动脉血样进行血气分析:气腹后(T1)和腹部减压前(T2)。比较两组在这两个时间点的动脉血氧分压(PaO2)和二氧化碳(PaCO2)水平、血氧饱和度(SpO2)和潮末二氧化碳。结果:P组Cdyn含量较高(43.21 ± 4.4 mL/cmH2O)与V组(39.18 ± 3.2 mL/cmH2O)和PV(40.37 ± 2.45 mL/cmH2O)(P<0.001)。P组的PaO2显著升高(P<0.01)(197.50 ± 17.29 mm Hg)与V组(178.90 ± 23.7 毫米汞柱)和PV(183.47 ± 22.99 毫米汞柱)。此外,P组的PaCO2也显著升高(40.19 ± 2.92 mm Hg)与V组(32.57 ± 2.09 mm Hg)和PV组(34.14 ± 3.27 毫米汞柱)。结论:压力控制模式下PaO2和动态顺应性较高,但压力控制模式中PaCO2较高表明通气不足。因此,压力控制容量保证模式可被视为LC期间的有利通气策略,因为动态顺应性和PaO2高于容量控制通气,PaCO2显著低于压力控制模式。
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引用次数: 0
Perioperative management in Rothmund–Thomson syndrome: A case report 罗斯蒙-汤姆森综合征围手术期治疗1例报告
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_244_22
A. Uslu, N. Çekmen
Rothmund-Thomson Syndrome (RTS) is a rare, multisystem disease accompanied by many anomalies that require careful attention from preoperative evaluation to discharge regarding anesthesia preparation and management. Due to craniofacial deformities accompanying facial abnormalities, maintaining the airway becomes a complete struggle with a race against time for survival. This case report presents the preoperative preparation and perioperative management, the risks that may be encountered, and the detailed preparation for a 7-year-old patient diagnosed with RTS and multiple system involvement. General anesthesia was administered to this patient, who had intrauterine growth retardation, nail streaking, redness of the bullae and legs, and a history of somatotropin treatment and antinuclear antibody (ANA) positivity under optimum conditions. Thanks to successful and detailed preoperative preparation and perioperative management, the patient was followed up and discharged without any complications. Although RTS is rare, the need for general anesthesia often arises due to juvenile cataracts, dental anomalies, syndactyly and other extremity anomalies in these patients whose airway management is complex. Furthermore, this increases the current risk in the population of these patients. Managing these patients with a multidisciplinary approach will reduce complications, morbidity, mortality, and length of stay.
Rothmund-Thomson综合征(RTS)是一种罕见的多系统疾病,伴有许多异常,从术前评估到出院,需要仔细注意麻醉准备和管理。由于颅面畸形伴随着面部异常,维持气道成为一场与时间赛跑的生存之战。本病例报告介绍了一名诊断为RTS和多系统受累的7岁患者的术前准备和围手术期管理、可能遇到的风险以及详细的准备。该患者全身麻醉,有宫内生长迟缓、指甲条纹、大疱和腿部发红,并有生长激素治疗史和最佳条件下的抗核抗体(ANA)阳性。由于成功而详细的术前准备和围手术期管理,患者得以随访并出院,没有任何并发症。尽管RTS很少见,但由于这些气道管理复杂的患者患有幼年白内障、牙齿异常、并指畸形和其他肢体异常,因此经常需要全身麻醉。此外,这增加了这些患者群体中目前的风险。采用多学科方法管理这些患者将减少并发症、发病率、死亡率和住院时间。
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引用次数: 0
Thoracic interfacial plane block versus thoracic paravertebral block for anesthesia in gynecomastia surgery: A randomized controlled trial 胸部界面平面阻滞与胸旁阻滞用于女性乳房发育术麻醉的随机对照试验
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_271_22
Taysser M. Abdelraheem, T. Naguib, A. Elkeblawy
Background: Gynecomastia is a benign proliferative condition affecting the glandular tissue of the male breast. This study compared the efficacy of ultrasound-guided thoracic interfacial plane block (TIPB) with ultrasound-guided thoracic paravertebral block (TPVB) in providing anesthesia for gynecomastia surgery. Materials and Methods: This prospective randomized open label clinical trial included 90 patients scheduled for elective surgery for idiopathic gynecomastia. Patients were randomly allocated into three equal groups: group C (control group) received bilateral tumescent local anesthesia, group TPVB received bilateral ultrasound guided TPVB, and group TIPB received bilateral ultrasound guided TIPB. We evaluated postoperative analgesic requirements, pain score, and patient’s satisfaction. Results: Intraoperative fentanyl requirement and total diclofenac in the first 24 hours postoperative were significantly lower in both TPVB and TIPB groups compared to control group (P = 0.002 and P < 0.001, respectively). Patient satisfaction was significantly better (P = 0.004) in both TPVB and TIPB groups when compared to control group. In postoperative evaluation, we found both TPVB and TIPB produced significantly lower pain score compared to control group in 2-hours (P < 0.001) and 4-hours (P = 0.001) after the surgery. Mean arterial blood pressure, heart rate, and peripheral oxygen saturation were comparable in all groups, as well as the occurrence of complications. Conclusion: Either TIPB and TPVB may provide effective analgesic property for anesthesia in gynecomastia surgery. This is shown by lower intraoperative analgesic requirements, lower postoperative pain score, and better patient’s satisfaction.
背景:女性乳腺癌是一种影响男性乳腺腺体组织的良性增生性疾病。本研究比较了超声引导下胸廓界面平面阻滞(TIPB)和超声引导下胸椎旁阻滞(TPVB)在为女性乳房发育症手术提供麻醉方面的疗效。材料和方法:这项前瞻性随机开放标签临床试验包括90名计划接受特发性女性乳房发育症选择性手术的患者。患者被随机分为三组:C组(对照组)接受双侧肿胀局部麻醉,TPVB组接受双侧超声引导的TPVB,TIPB组接受双侧超声波引导的TIPB。我们评估了术后镇痛需求、疼痛评分和患者满意度。结果:与对照组相比,TPVB组和TIPB组术中芬太尼需求量和术后前24小时的双氯芬酸总量均显著降低(分别为P=0.002和P<0.001)。与对照组相比,TPVB和TIPB组的患者满意度显著提高(P=0.004)。在术后评估中,我们发现与对照组相比,TPVB和TIPB在术后2小时(P<0.001)和4小时(P=0.001)的疼痛评分均显著降低。各组的平均动脉血压、心率和外周血氧饱和度以及并发症的发生率具有可比性。结论:TIPB和TPVB均可为女性乳房发育术的麻醉提供有效的镇痛效果。这表现为术中镇痛要求较低,术后疼痛评分较低,患者满意度较高。
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引用次数: 0
Risk Factors for development of invasive candidiasis in critically ill patients: A prospective observational study in intensive care unit of a tertiary hospital 危重患者侵袭性念珠菌病发生的危险因素:某三级医院重症监护病房的前瞻性观察研究
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_255_22
R. Sedono, A. Adisasmita, R. Djuwita, A. Sjaaf, M. Nadjib, S. Syarif, B. Alisjahbana, A. Karuniawati, R. Wahyuningsih
Background: Majority of invasive candidiasis in critically ill patients was developed after admission to intensive care unit. The aim of this study was to identify risk factors for development of invasive candidiasis among patients admitted to intensive care unit, especially considering the timing of laboratory, microscopic, and culture examinations. Materials and Methods: This was a prospective observational study in which critically ill patients were assessed on the first, fifth, and ninth day since admission to intensive care unit. Potential risk factors were demographic and clinical characteristic, clinical managements profile proportions, laboratory profile (leukocyte, platelet, erythrocyte sedimentation rate, C-reactive protein and procalcitonin), morphological change (from yeast to hypae or pseudohyphae in microscopic examination) and colonization increase (from serial culture examination). Results: A total of 115 subjects enrolled in this study. Multivariate analysis identified older age (HR 2.8, 95% CI 0.8–8.9), parenteral nutrition (HR 3.1, 95% CI 0.77–12.3), central venous catheter (HR 1.7, 95% CI 0.43–6.67), corticosteroid (HR 2.8, 95% CI 0.53–14.8), procalcitonin day-5 (HR 3.1, 95% CI 0.89–10.8), morphology change in the axilla and rectal swab (HR 5.1, 95% CI 1.6–18.51), and morphology change and colonization increase in rectal swab day-9 (HR 4.3, 95% CI 1.0–18.02) as independent risk factors of invasive candidiasis. Conclusion: In addition to several typical risk factors, procalcitonin test on day-5 as well as serial microscopic and culture examinations were associated with the development of invasive candidiasis, therefore potentially help in the diagnosis and treatment of critically ill patients in intensive care unit.
背景:大多数危重患者侵袭性念珠菌病是在重症监护病房入院后发生的。本研究的目的是确定入住重症监护病房的患者中侵袭性念珠菌病发展的危险因素,特别是考虑到实验室、显微镜和培养检查的时间。材料和方法:这是一项前瞻性观察性研究,在重症监护病房入院后的第1天、第5天和第9天对危重患者进行评估。潜在的危险因素包括人口统计学和临床特征、临床管理情况、实验室情况(白细胞、血小板、红细胞沉降率、c反应蛋白和降钙素原)、形态变化(显微镜检查从酵母菌到菌丝或假菌丝)和定植增加(从连续培养检查)。结果:本研究共纳入115名受试者。多因素分析发现,年龄较大(HR 2.8, 95% CI 0.8-8.9)、肠外营养(HR 3.1, 95% CI 0.77-12.3)、中心静脉导管(HR 1.7, 95% CI 0.43-6.67)、皮质类固醇(HR 2.8, 95% CI 0.53-14.8)、降钙素原第5天(HR 3.1, 95% CI 0.89-10.8)、腋下和直肠棉签形态改变(HR 5.1, 95% CI 1.6-18.51)以及第9天直肠棉签形态改变和定植增加(HR 4.3, 95% CI 1.0-18.02)是浸润性念珠菌病的独立危险因素。结论:除几个典型的危险因素外,第5天降钙素原试验以及一系列的显微镜和培养检查与侵袭性念珠菌病的发生有关,因此可能有助于重症监护室危重患者的诊断和治疗。
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引用次数: 0
The impact of vaccination to clinical severity and mortality of COVID-19 patients 疫苗接种对COVID-19患者临床严重程度和死亡率的影响
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_268_22
C. Purnamasidhi, P. Januraga, N. M. Sukmawati, Anak Agung Ayu Yuli Gayatri, I. Utama, I. Somia, K. Merati, R. Suteja, G. Purnama
Background: SARS-CoV-2 was discovered in December 2019 and later become global pandemic. Preliminary studies stated that broad vaccine coverage will suppress mortality and incidence of COVID-19. Therefore, we conduct a cross-sectional study to assess the efficacy of COVID-19 vaccination. Materials and Methods: We collected secondary data from electronic medical records of 343 COVID-19 positive patients confirmed via reverse transcription polymerase chain reaction from July 2021 to December 2021. We analyzed epidemiologic data, vaccination history, baseline symptoms, comorbidity, baseline vital signs, and outcome using hypothesis testing χ2 and logistic regression. Results: Sex had an χ2 of 9.34 (P < 0.001) while type of vaccine had an χ2 of 1.49 (P = 0.22) to clinical severity. Age, pulse rate, respiration rate, body temperature, and Glasgow coma scale were found to be significant risk factors to clinical severity. Number of vaccines previously received was found to be a protective factor to clinical severity (odds ratio (OR) = 0.49, 95% CI = 0.32–0.74, P < 0.001). We also found that sex (χ2 = 10.42, P < 0.001) was a predictor to discharge condition. Moreover, age was also found to be a significant predictor (OR = 1.03, 95% CI = 1.03–1.05, P < 0.001), as well as number of symptoms (OR = 0.66, P < 0.001), comorbidities (OR = 1.64, P < 0.001), pulse rate (OR = 1.04, P < 0.001), respiration rate (OR = 1.17, P < 0.001), and Glasgow coma scale (OR = 0.72, P = 0.03). Conclusion: Age, sex, number of vaccines received, number of symptoms, number of comorbidities, pulse rate, and respiration rate were significant predictors of clinical severity and outcome in COVID-19 patients. In addition, body temperature was also a predictor for clinical severity, while Glasgow coma scale was a predictor for outcome.
背景:SARS-CoV-2于2019年12月被发现,后来成为全球大流行。初步研究表明,广泛的疫苗覆盖率将抑制COVID-19的死亡率和发病率。因此,我们进行了一项横断面研究来评估COVID-19疫苗接种的效果。材料与方法:从2021年7月至2021年12月通过逆转录聚合酶链反应确诊的343例COVID-19阳性患者的电子病历中收集二次资料。我们使用假设检验χ2和logistic回归分析流行病学资料、疫苗接种史、基线症状、合并症、基线生命体征和结局。结果:性别与临床严重程度的χ2为9.34 (P < 0.001),疫苗类型与临床严重程度的χ2为1.49 (P = 0.22)。年龄、脉搏率、呼吸率、体温和格拉斯哥昏迷评分是影响临床严重程度的重要危险因素。先前接种的疫苗数量被发现是临床严重程度的保护因素(优势比(OR) = 0.49, 95% CI = 0.32-0.74, P < 0.001)。我们还发现性别(χ2 = 10.42, P < 0.001)是出院状况的预测因子。此外,年龄也是一个重要的预测因子(OR = 1.03, 95% CI = 1.03 - 1.05, P < 0.001),以及症状数量(OR = 0.66, P < 0.001)、合并症(OR = 1.64, P < 0.001)、脉搏率(OR = 1.04, P < 0.001)、呼吸率(OR = 1.17, P < 0.001)和格拉斯哥昏迷量表(OR = 0.72, P = 0.03)。结论:年龄、性别、接种疫苗次数、症状次数、合并症次数、脉搏率和呼吸率是影响COVID-19患者临床严重程度和预后的重要预测因素。此外,体温也是临床严重程度的预测指标,而格拉斯哥昏迷量表是预后的预测指标。
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引用次数: 0
Comparison of the patient state index and bispectral index in patients with complex regional pain syndrome undergoing ketamine infusion therapy: Case series 氯胺酮输注治疗复杂局部疼痛综合征患者状态指数和双谱指数的比较:病例系列
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_236_22
K. Lee, S. Lee
It is important for clinicians to perform a continuous comprehensive assessment of the depth of sedation, including the use of processed electroencephalographic monitors and the review of clinical signs. Ketamine is a safe anesthetic and sedative traditionally used in the clinical practice. It possesses analgesic, anti-inflammatory, and antidepressant activities and is used as a therapeutic agent in intractable pain. In this case series, we present a comparison between patient state index (PSI) and bispectral index (BIS) in a sample of eight patients with complex regional pain syndrome undergoing ketamine infusion therapy. Blood pressure, heart rate, respiratory rate, end-tidal carbon dioxide, and oxygen saturation were all noted, as well as the PSI and BIS values. The PSI and BIS readings were not recorded when the artifact was larger than 50%. Four patients (50%) received intravenous midazolam 5 mg when their agitation or movement could not be managed by the clinicians’ verbal instructions. In five patients (62%), 20 min after the ketamine infusion began, deep drowsiness was attained. There are fewer research studies on PSI than there are on BIS. We found that PSI values did not match BIS values. This case series could help clinicians select an appropriate course of action for ketamine sedation in individual patients.
临床医生对镇静深度进行持续的全面评估是很重要的,包括使用经过处理的脑电图监测仪和审查临床体征。氯胺酮是一种安全的麻醉剂和镇静剂,传统上用于临床实践。它具有镇痛、抗炎和抗抑郁活性,被用作顽固性疼痛的治疗剂。在这个病例系列中,我们对8名接受氯胺酮输注治疗的复杂区域疼痛综合征患者的样本进行了患者状态指数(PSI)和双频谱指数(BIS)之间的比较。血压、心率、呼吸频率、潮末二氧化碳和血氧饱和度,以及PSI和BIS值都被记录下来。当伪影大于50%时,不记录PSI和BIS读数。4名患者(50%)接受静脉注射咪达唑仑5 当他们的激动或运动不能通过临床医生的口头指示来控制时。在5名患者(62%)中 氯胺酮输注开始后min,出现深度嗜睡。与BIS相比,对PSI的研究较少。我们发现PSI值与BIS值不匹配。该系列病例可以帮助临床医生为个别患者选择合适的氯胺酮镇静方案。
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引用次数: 0
Enhanced recovery after surgery in geriatric patients: A need to fly in the face of convention 提高老年患者手术后的恢复:需要在传统面前飞翔
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_3_23
N. Govil
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引用次数: 0
Lumbar epidural anesthesia in a high-risk patient with advanced lung cancer, multi-organ metastasis and hydropneumothorax: A case report 腰椎硬膜外麻醉治疗晚期肺癌多器官转移并发气胸1例
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_248_22
A. Uslu, N. Çekmen
Epidural anesthesia (EA) can be applied in the perioperative period (PP) in addition to general anesthesia (GA) or as a stand-alone anesthesia technique. EA provides better hemodynamic stability in high-risk patients, reduced neurohormonal surgical stress response, and preserved airway reflexes with spontaneous breathing. In addition, EA prevents pulmonary dysfunction through decreasing multifactorial mediators, improves pulmonary functions by reducing the decrease in functional residual capacity, and protects spontaneous respiratory and airway reflexes. Herein, we wanted to emphasize the importance of the perioperative approach, the choice of anesthesia technique, and the effects of this choice on the postoperative period in a high-risk patient with incidental stage four lung adenocarcinoma, right parietal brain, lumbar vertebral, liver, and adrenal metastasis, as well as hydropneumothorax. With a successful epidural catheterization and anesthesia, the patient was follow-up without any problems. As in our patient, we should adopt a multimodal approach in the perioperative period, perform a detailed examination before the operation, and evaluate all risks and benefits comparatively when choosing the most appropriate anesthesia technique. Thus, it should be kept in mind that the chosen technique will significantly affect perioperative complications, morbidity and mortality, drug use, length of hospital stay, and cost.
硬膜外麻醉(EA)除了全身麻醉(GA)外,也可以作为一种独立的麻醉技术应用于围手术期(PP)。EA为高危患者提供了更好的血液动力学稳定性,减少了神经激素手术应激反应,并保留了自主呼吸的气道反射。此外,EA通过减少多因素介质来预防肺功能障碍,通过减少功能残余容量的减少来改善肺功能,并保护自发呼吸和气道反射。在此,我们想强调围手术期方法的重要性,麻醉技术的选择,以及这种选择对一名偶发四期肺腺癌、右顶脑、腰椎、肝脏和肾上腺转移以及水肺的高危患者术后期的影响。在硬膜外导管插入术和麻醉成功的情况下,患者进行了随访,没有出现任何问题。与我们的患者一样,我们应该在围手术期采用多模式方法,在手术前进行详细检查,并在选择最合适的麻醉技术时比较评估所有风险和益处。因此,应该记住,所选择的技术将显著影响围手术期并发症、发病率和死亡率、药物使用、住院时间和成本。
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引用次数: 1
Analgesic efficacy of erector spinae plane block versus transversus abdominis plane block in laparotomies for cancer surgeries: A randomized blinded control study 直立脊柱平面阻滞与腹横平面阻滞在癌症腹腔镜手术中的镇痛效果:一项随机盲法对照研究
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_229_22
Ahmed H Bakeer, W. Hamimy, A. Zaghloul, A. Shaban, M. Magdy, Mahmoud Ahmed
Background: Pain has a wide spectrum of effects on the body and inadequate management of postoperative pain outcomes in multiple physiological and psychological consequences; and increases morbidity. The use of opioid-based analgesia in high doses can have multiple adverse effects including respiratory depression, nausea, and vomiting. Objectives: Our aim was to evaluate the efficacy of analgesic and safety of both techniques (transversus abdominis plane block [TAPB] and erector spinae plane block [ESPB]) in cases having lower abdominal surgery through laparotomy. Materials and Methods: This randomized trial was performed on 62 cases who underwent laparotomy for lower abdominal surgery under general anesthesia were recruited. Subjects were equally distributed into either TAPB or ESPB. The primary outcome was total morphine intake postoperatively for 24 h. Other variables were intraoperative fentanyl consumption, delay to first morphine demand, and intraoperative morphine consumption, the number of patients who needed rescue analgesia by morphine, perioperative heart rate and mean blood pressure, numerical rating score (NRS), postoperative nausea and vomiting, and block-related complications. Results: ESPB patients consumed less total postoperative morphine than the TAPB group (5.35 ± 2.65 vs. 8.52 ± 3.35 mg; P < 0.001). Patients who received ESPB showed less postoperative pain scores and, thus, needed rescue medication after a longer period than the TAPB group (12.50 ± 7.31 h vs. 7.72 ± 5.69 h; P = 0.008). In addition, ESPB patients needed less intraoperative fentanyl doses than TAPB (138.71 ± 35.85 vs. 203.23 ± 34.00 mcg; P < 0.001). ESPB group demonstrated statistically significant lower scores of NRS at rest and at movement. Conclusions: Ultrasound (US)-guided ESPB provides more safe and effective analgesia in lower abdominal surgeries compared with US-guided TAPB.
背景:疼痛对身体有广泛的影响,对术后疼痛结果的管理不当会产生多种生理和心理后果;并增加发病率。高剂量使用阿片类镇痛可能会产生多种不良反应,包括呼吸抑制、恶心和呕吐。目的:我们的目的是评估两种技术(腹横肌平面阻滞[TAPB]和竖脊肌平面阻滞[ESPB])在剖腹下腹手术中的镇痛效果和安全性。材料和方法:本随机试验对62例全麻下腹部手术患者进行了研究。受试者被平均分配到TAPB或ESPB。主要结果是术后24小时的吗啡总摄入量 h.其他变量包括术中芬太尼用量、首次吗啡需求延迟和术中吗啡用量、需要吗啡镇痛的患者人数、围手术期心率和平均血压、数值评分(NRS)、术后恶心呕吐和阻滞相关并发症。结果:ESPB患者术后吗啡消耗总量低于TAPB组(5.35 ± 2.65对8.52 ± 3.35 mg;P<0.001)。与TAPB组相比,接受ESPB的患者术后疼痛评分较低,因此需要更长时间的抢救药物(12.50 ± 7.31 h与7.72 ± 5.69 h;P=0.008)。此外,ESPB患者比TAPB患者需要更少的术中芬太尼剂量(138.71 ± 35.85对203.23 ± 34.00微克;P<0.001)。ESPB组在休息和运动时的NRS评分具有统计学意义。结论:超声引导的ESPB与超声引导的TAPB相比,在下腹手术中提供了更安全有效的镇痛。
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引用次数: 1
Clinical improvement and tumor regression in parturient with a brain tumor and intracranial bleeding after C-section with general anesthesia: A case report 全麻剖宫产后脑肿瘤合并颅内出血产妇临床改善及肿瘤消退1例
Q4 Nursing Pub Date : 2023-01-01 DOI: 10.4103/bjoa.bjoa_250_22
I. Isngadi, R. Hartono, Andreas Willianto
Brain tumors and intracranial bleeding are rare cases in pregnancy. Anesthesia management for a C-section with comorbidity remains challenging. We presented a 33-year-old woman (34–36 weeks pregnant) with the complaint of weakness in her right extremities, blurred vision, and ptosis of her left eye from a month before hospitalization. The brain computed tomography (CT) revealed a mass at the left parasellar region with a bleeding component and cerebral edema accompanied by subfalcine herniation. We conducted general anesthesia for cesarean delivery in a patient with a brain-protective technique. Brain CT revealed a decrease in the mass size and neither intracranial bleeding nor cerebral edema. In conclusion, general anesthesia management provided a good outcome in a parturient with a brain tumor and intracranial bleeding that underwent C-section. The mechanism of clinical improvement and tumor regression is unclear and requires further research, but it is believed that it is related to pregnancy hormones.
脑肿瘤和颅内出血在妊娠期是罕见的。伴有合并症的剖腹产的麻醉管理仍然具有挑战性。我们报告了一名33岁的女性(怀孕34-36周),她在住院前一个月的主诉是右肢无力、视力模糊和左眼上睑下垂。脑部电脑断层扫描(CT)显示左侧鞍旁区有一个肿块,伴有出血和脑水肿,并伴有镰下疝。我们采用脑保护术对剖宫产患者进行全身麻醉。脑CT显示肿块大小减小,无颅内出血和脑水肿。总之,全麻管理提供了一个良好的结果,产妇脑肿瘤和颅内出血行剖腹产。临床改善和肿瘤消退的机制尚不清楚,需要进一步研究,但认为与妊娠激素有关。
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Bali Journal of Anesthesiology
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