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Determinants of hormonal contraceptive use and its effects among married women of reproductive age group in Kathmandu, Nepal 尼泊尔加德满都已婚育龄妇女使用激素避孕药的决定因素及其影响
Pub Date : 2022-06-27 DOI: 10.3126/nmcj.v24i2.46038
S. Shrestha, V. Silvanus, B. Shakya
The prevention of unwanted pregnancy, unsafe abortion and maternal mortality remains an important part of the practice of medicine. Several forms of hormonal contraception have been used to control female fertility. These are associated with benefits and risk. The current study aimed to study the determinants of hormonal contraceptive use and its effects among married women of reproductive age group in Kathmandu. This is a community based cross sectional study among 250 married women using hormonal contraceptives aged between 15-49 years residing in wards 8 and 9 of Gokarneshwor Municipality. The information was obtained using self-constructed structured questionnaire. Height, weight and blood pressure were recorded and hypertension was defined as per Joint National Committee (JNC) VII guidelines. Around one third of the participants were of 30-34 years and Depo-Provera was the most commonly used hormonal contraceptive. There were several side effects among the users and commonest were menstrual irregularities and weight gain. Around 47 participants had hypertension and 120 had raised BMI. The factors associated with hormonal contraceptive use were socioeconomic status, religion, BMI and monthly income of family of the study population. The present study provides valuable information regarding significant positive correlation of age, BMI and duration of hormonal contraceptive use with systolic and diastolic BP.
预防意外怀孕、不安全堕胎和孕产妇死亡仍然是医学实践的重要组成部分。几种激素避孕方法已被用于控制女性生育能力。这些都与收益和风险有关。本研究旨在研究加德满都育龄已婚妇女使用激素避孕药的决定因素及其影响。这是一项基于社区的横断面研究,对居住在Gokarneshwor市8至9号病房的250名年龄在15-49岁之间的已婚女性进行了研究。这些信息是通过自行构建的结构化问卷获得的。记录身高、体重和血压,并根据联合国家委员会(JNC)VII指南定义高血压。大约三分之一的参与者年龄在30-34岁之间,Depo Provera是最常用的激素避孕药。使用者有几种副作用,最常见的是月经不规律和体重增加。大约47名参与者患有高血压,120名参与者的BMI升高。与激素避孕药使用相关的因素是研究人群的社会经济地位、宗教、BMI和家庭月收入。本研究提供了关于年龄、BMI和激素避孕药使用时间与收缩压和舒张压显著正相关的有价值的信息。
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引用次数: 0
Prevalence of intestinal parasitic infection among school children in Kirtipur Municipality, Kathmandu 加德满都Kirtipur市学童肠道寄生虫感染的患病率
Pub Date : 2022-06-27 DOI: 10.3126/nmcj.v24i2.46027
Amulya Dahal, Dev Bahadur Roka, Shivneel Prasad, Srishti Shrestha
Intestinal parasitic infections are a major cause of morbidity in developing countries including Nepal. Most common intestinal parasites reported in Nepal are Ascaris lumbricoides, Hymenolepis nana, Hookworm, Trichuris trichiura, Giardia lamblia and Entamoeba histolytica. This study aimed to find out the prevalence of various intestinal parasitic infections among school children in Kirtipur Municipality, Kathmandu. A cross-sectional observational study was carried out with prepared questionnaire and stool examination between October to November, 2021. Altogether, 409 stool samples were randomly collected from different schools and examined by direct smear method. Out of 409 stool samples, 73 (17.8%) were positive and 336 (82.1%) were negative. Among positive cases, helminthic infection was seen in 45 (11.0%) and protozoan infection was found in 28 (6.8%). Altogether eight species of intestinal parasites were detected, the most common was A. lumbricoides (34.2%), followed by protozoa G. lamblia (23.3%), E. histolytica (15.1%), T. trichiura (10.96%), Hookworm (6.8%), Enterobius vermicularis (4.11%), Taenia solium (4.11%) and H. nana (1.37%) respectively. Study showed that, there was 63 (86.30%) single infections, 9 (12.33%) double infections and 1 (1.37%) multiple infection. The present study reveals that intestinal parasites are abundant among students of Kirtipur Municipality, Kathmandu. The situation strongly calls for the use of control measures including treatment of infected individuals, improvement of health status of infected students by health education, public health awareness and also develop the health care facilities and aware the people for the utilization of health services.
肠道寄生虫感染是包括尼泊尔在内的发展中国家发病率的主要原因。在尼泊尔报告的最常见的肠道寄生虫是蛔虫、膜壳绦虫、钩虫、鞭虫、蓝氏贾第虫和溶组织内阿米巴。本研究旨在了解加德满都Kirtipur市学童中各种肠道寄生虫感染的流行情况。在2021年10月至11月期间,利用准备好的问卷和粪便检查进行了一项横断面观察性研究。共从不同学校随机抽取409份粪便样本,采用直接涂片法进行检查。在409份粪便样本中,73份(17.8%)呈阳性,336份(82.1%)呈阴性。在阳性病例中,蠕虫感染45例(11.0%),原生动物感染28例(6.8%)。共检测到8种肠道寄生虫,最常见的是蛔虫(34.2%),其次是原生动物兰氏鞭毛虫(23.3%)、溶组织大肠杆菌(15.1%)、毛毛虫(10.96%)、钩虫(6.8%,猪带绦虫(4.11%)和海南带绦虫(1.37%)。研究表明,单次感染63例(86.30%),双重感染9例(12.33%),多重感染1例(1.37%)。本研究表明,在加德满都Kirtipur市的学生中,肠道寄生虫非常多。这种情况强烈要求采取控制措施,包括治疗受感染者、通过健康教育改善受感染学生的健康状况、提高公众健康意识,以及发展卫生保健设施和提高人们利用卫生服务的意识。
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引用次数: 2
Morphometric profile of achilles tendon in male - a cadaveric study 男性跟腱形态计量学研究
Pub Date : 2022-06-27 DOI: 10.3126/nmcj.v24i2.46039
C. Lama, U. Chalise, A. Shrestha, S. Dhungel
The Achilles tendon is a conjoined tendon of gastrocnemius and soleus muscles and occasionally may have a small contribution from plantaris muscle. Despite being the strongest and thickest tendon in the body it is a frequent site of degenerative changes, inflammation and rupture. The main objective of this study was to measure and analyze the various parameters of Achilles tendon in cadavers. An observational, descriptive study was conducted from August 2021 to February 2022 in the Department of Human Anatomy of Nepal Medical College Teaching Hospital, Attarkhel, Gokarneshwor – 8, Kathmandu, Nepal which included forty lower limbs of twenty male cadavers. The various parameters recorded were (a) mean length of right Achilles tendon was 16.65 ± 1.72 cm, (b) mean proximal width of right Achilles tendon was 5.50 ± 1.07 cm, (c) mean proximal circumference of right Achilles tendon was 10.67 ± 2.20 cm, (d) mean distal width of right Achilles tendon was 2.22 ± 0.54 cm, (e) mean distal circumference of right Achilles tendon was 4.27 ± 0.67 cm, (f ) mean length of left Achilles tendon was 16.35 ± 1.49 cm, (g) mean proximal width of left Achilles tendon was 5.25 ± 0.88 cm, (h) mean proximal circumference of left Achilles tendon was 10.57 ± 1.78 cm, (i) mean distal width of left Achilles tendon was 2.05 ± 0.27 cm and mean distal circumference of left Achilles tendon was 4.0 ± 0.42 cm. The present morphometric evaluation of Achilles tendon in cadavers can be of substantial help to clinicians before determining its pathological conditions and can also be of help to surgeons during the surgical repair and reconstruction of damaged tendon.
跟腱是腓肠肌和比目鱼肌的连接肌腱,偶尔也有一小部分来自跖肌。尽管是身体中最强壮和最厚的肌腱,但它是一个经常发生退行性变化,炎症和断裂的部位。本研究的主要目的是测量和分析尸体跟腱的各种参数。从2021年8月至2022年2月,在尼泊尔加德满都Gokarneshwor - 8区Attarkhel尼泊尔医学院教学医院人体解剖学系进行了一项观察性描述性研究,其中包括20具男性尸体的40个下肢。记录各种参数(a)意味着对跟腱长度是16.65±1.72厘米,宽度(b)的意思是近端右跟腱是5.50±1.07厘米,(c)意味着近围的跟腱是10.67±2.20厘米,(d)远端右跟腱的宽度是2.22±0.54厘米,(e)的意思是远端周长的跟腱是4.27±0.67厘米,(f)的意思是左跟腱长度是16.35±1.49厘米,(g)左跟腱近端平均宽度5.25±0.88 cm, (h)左跟腱近端平均周长10.57±1.78 cm, (i)左跟腱远端平均宽度2.05±0.27 cm,远端平均周长4.0±0.42 cm。目前对尸体跟腱的形态学评估可以在确定其病理状况之前为临床医生提供实质性的帮助,也可以在手术修复和重建受损跟腱时为外科医生提供帮助。
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引用次数: 1
Assessment of knowledge, attitude and practice of pharmacovigilance among people working in community pharmacy: a cross-sectional study at Banke District in Nepal 评估社区药房工作人员的药物警戒知识、态度和实践:尼泊尔班克地区的一项横断面研究
Pub Date : 2022-06-27 DOI: 10.3126/nmcj.v24i2.46042
A. Chaudhary, A. Gupta, B. Kc, Niraj Prasad Sah, D. Sarraf
The burden of ADRs is high globally and it accounts for considerable morbidity, mortality, and extra cost to the patients. Pharmacovigilance plays a significant role in the detection, assessment, understanding and reporting of ADRs. Objective of the study was to assess the knowledge, attitude and practice of pharmacovigilance among people working in community pharmacies in the Banke District. A prospective cross-sectional descriptive study was conducted among people working in community pharmacies in Banke district from February to March 2022 using a 20 item semi-structured questionnaire. Ethical approval was obtained from the institutional ethical review committee (501/078-079). Data were entered in Microsoft Office Excel 2010 and descriptive statistics like mean, frequency, percentage and standard deviation were calculated. Data were analyzed using SPSS-22 and data were presented as tables. Only 46 (22.89%) respondents knew the definition of pharmacovigilance. Mean knowledge score of the respondents was 2.87±2.05 out of the maximum possible score of 10. Only 40 (19.9%) respondents had knowledge score ≥50%. Out of 201, 180 (89.55%) respondents thought that reporting of adverse drug reaction will be beneficial in the future. A total of 136 (67.66%) respondents had positive attitude towards pharmacovigilance. One hundred and seventy seven (88.06%) had not seen ADR reporting form. A total of 166 (82.59%) respondents had poor practice towards pharmacovigilance. Majority of the respondents had poor knowledge, positive attitude and poor practice of pharmacovigilance. There is urgent need of educational programs on pharmacovigilance to raise awareness.
ADR的负担在全球范围内都很高,它导致了相当大的发病率、死亡率和患者的额外费用。药物警戒在药物不良反应的检测、评估、理解和报告方面发挥着重要作用。本研究的目的是评估班克区社区药房工作人员的药物警戒知识、态度和实践。2022年2月至3月,在班克区社区药房工作的人群中进行了一项前瞻性横断面描述性研究,使用20项半结构化问卷。获得了机构伦理审查委员会的伦理批准(501/078-079)。数据输入到Microsoft Office Excel 2010中,并计算平均值、频率、百分比和标准差等描述性统计数据。使用SPSS-22对数据进行分析,数据以表格形式呈现。只有46名(22.89%)受访者知道药物警戒的定义。受访者的平均知识得分为2.87±2.05,最大可能得分为10分。只有40名(19.9%)受访者的知识得分≥50%。在201名受访者中,180名(89.55%)受访者认为报告药物不良反应对未来有益。共有136名(67.66%)受访者对药物警戒持积极态度。一百七十七人(88.06%)没有看到不良反应报告表。共有166名(82.59%)受访者对药物警戒实践不佳。大多数受访者对药物警戒知识贫乏、态度积极、实践不力。迫切需要药物警戒教育项目来提高人们的认识。
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引用次数: 0
Medication adherence among chronic obstructive pulmonary disease patients: an interventional study in a tertiary care hospital of Nepal 尼泊尔一家三级护理医院慢性阻塞性肺病患者的药物依从性干预研究
Pub Date : 2022-06-27 DOI: 10.3126/nmcj.v24i2.46021
A. Yadav, Najma Khatun, P. Chhetri
Chronic Obstructive Pulmonary Disease (COPD) is a significant health problem, associated with mortality and morbidities. Low medication adherence is common in patients with COPD. The primary purpose of this study was to evaluate medication adherence after educational intervention was provided to COPD patients. In this interventional study, conducted at a tertiary care center of Nepal from July 2019 to December 2019, a total of 114 patients were divided randomly into two groups: intervention group (patients who received an educational intervention) and control group (patients who received no educational intervention) by using simple randomization technique. The outcomes of educational intervention are then compared between the intervention group and the control group with the aid of the leaflet. A structured questionnaire and the pre-validated Self-Administered Medication Adherence Questionnaire were used to collect information like demographic details and medication adherence. Data were entered and analyzed using SPSS-20 program. Out of 114 patients, only 93 patients came for follow-up after one month. There was a significant improvement in the medication adherence scale score in the intervention group compared to the control group (p <0.05) and the level of adherence was found to be high in the intervention group after one-month follow-up. The major reasons for medication non-adherence were financial problems and symptomatic relief in both groups. This study showed that educational intervention among COPD patients plays an essential role in improving medication adherence through proper counseling about their disease and its maintenance.
慢性阻塞性肺疾病(COPD)是一个重要的健康问题,与死亡率和发病率有关。低药物依从性在COPD患者中很常见。本研究的主要目的是评估COPD患者在接受教育干预后的药物依从性。本研究于2019年7月至2019年12月在尼泊尔某三级医疗中心进行,采用简单随机化方法将114例患者随机分为干预组(接受教育干预的患者)和对照组(未接受教育干预的患者)。然后在传单的帮助下比较干预组和对照组的教育干预结果。使用结构化问卷和预先验证的自我服药依从性问卷来收集人口统计细节和服药依从性等信息。采用SPSS-20程序进行数据录入和分析。114名患者中,只有93名患者在1个月后进行了随访。干预组患者服药依从性量表评分较对照组有显著提高(p <0.05),随访1个月后发现干预组患者服药依从性水平较高。两组患者服药不依从的主要原因是经济问题和症状缓解。本研究表明,通过对COPD患者的疾病及其维持进行适当的咨询,教育干预在提高药物依从性方面发挥着重要作用。
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引用次数: 0
Study of variations in origin and course of cystic artery in relation to Calot’s triangle 与卡洛三角有关的囊性动脉起源及走行变异的研究
Pub Date : 2022-06-27 DOI: 10.3126/nmcj.v24i2.46028
A. Pradhan, C. Lama, S. Dhungel
Calot’s triangle is an anatomical space and also known as “triangle of cholecystectomy”. It is bounded medially by Common hepatic duct, laterally by cystic duct, and superiorly by the under surface of liver and its main contain is Cystic artery. The variation in the origin and course of the cystic artery can cause serious problems resulting, severe arterial bleeding during any surgical procedures. Hence, variations in the Calot’s triangle are very important for the surgeons. An observational cross sectional study was carried out in Department of Anatomy of two Medical Colleges in Kathmandu, Nepal. A total of 30 embalmed human cadavers were dissected, in 27 cases (90.0%), cystic artery arose from right hepatic arteries, the mean length was 11.47 mm. One (3.3%) cystic artery arose from proper hepatic artery, one (3.3%) from superior mesenteric artery and one (3.3%) from accessory hepatic artery and the length of the cystic arteries were found to be measured as 15.88 mm, 27.49 mm and 24.17 mm respectively. The cystic artery was also found to be lying inside and outside the Calot‘s triangle in 96.7% and 3.3% respectively. In 26 cases (86.7%) cystic arteries were observed as passing posterior to the common hepatic duct. Further in 2 cases (6.7%) cystic arteries were found to be lying anterior to the common hepatic duct. Result also showed as in 1 case (3.3%) it was running anterior to the bile duct and in 1 case (3.3%) between right and left hepatic ducts. In conclusion the variations in the origin and course of the cystic artery are essential in performing cholecystectomy (open or laparoscopic).
卡洛三角是一个解剖空间,又称“胆囊切除三角”。中间以肝总管为界,外侧以肝囊管为界,上部以肝下表面为界,其主要包含囊动脉。囊性动脉的起源和路线的变化会导致严重的问题,导致在任何外科手术中严重的动脉出血。因此,卡洛三角的变化对外科医生来说是非常重要的。在尼泊尔加德满都的两所医学院解剖学系进行了一项观察性横断面研究。共解剖30具尸体,27例(90.0%)囊性动脉起源于右肝动脉,平均长度为11.47 mm。囊性动脉来自肝固有动脉1条(3.3%),来自肠系膜上动脉1条(3.3%),来自肝副动脉1条(3.3%),囊性动脉长度分别为15.88 mm、27.49 mm和24.17 mm。囊性动脉位于卡洛三角区内外,分别占96.7%和3.3%。26例(86.7%)囊性动脉经肝总管后方。2例(6.7%)囊性动脉位于肝总管前部。1例(3.3%)位于胆管前方,1例(3.3%)位于左右肝管之间。总之,胆囊动脉的起源和路线的变化在胆囊切除术(开放或腹腔镜)中是必不可少的。
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引用次数: 0
Knowledge regarding obstetric danger signs among mother attending antenatal clinic at Scheer Memorial Adventist Hospital, Banepa, Kavre 在卡弗雷巴内帕舍尔纪念基督复临医院产前诊所就诊的母亲对产科危险体征的了解
Pub Date : 2022-06-27 DOI: 10.3126/nmcj.v24i2.46016
Nirmala Manandhar, M. Tamang
Knowledge about obstetric danger signs is very crucial for preventing obsterric complication. Globally there was 211 maternal deaths per 1,00,000 live birth in 2017. The maternal mortality ratio for Nepal is 239 deaths per 1,00,000 live births in 2016. A descriptive cross sectional study was conducted to assess the knowledge regarding obstetric danger signs among pregnant mother attending ANC at Scheer Memorial Adventist Hospital, Banepa, Kavre, Nepal. Total 100 respondents were selected using non probability purposive sampling technique through a semi-structured interview questionnaire. Data were analyzed in SPSS-16 using descriptive statistics (mean, frequency, standard deviation and percentage) and inferential statistic Chi Square. The study shows that mean age of the respondents was 25.56±4.307. More than half of the respondents (53%) were from 15-25 age group. Majority of respondent (97%) were literate. Fifty six percent of respondents had adequate knowledge on obstetric danger signs, while 27% of respondents had moderate knowledge and few respondents (17%) had inadequate knowledge. There is no any significant relationship with knowledge with selected variable age, educational status, gravida, week of gestation and -number of ANC visit. Thus it is concluded about that the entire pregnant mother requires some interventions for the awareness regarding obstetric danger signs from the beginning of ANC visit. ANC visit should be focused more than eight times as recommended by WHO.
了解产科危险信号对于预防顽固性并发症至关重要。2017年,全球每10万活产中有211名产妇死亡。2016年,尼泊尔的孕产妇死亡率为每100000活产239人死亡。进行了一项描述性横断面研究,以评估在尼泊尔Kavre Banepa舍尔纪念基督复临安息日会医院参加ANC的孕妇对产科危险信号的了解。通过半结构化访谈问卷,采用非概率目的抽样技术选择了总共100名受访者。数据在SPSS-16中使用描述性统计(平均值、频率、标准差和百分比)和推断统计卡方进行分析。研究表明,受访者的平均年龄为25.56±4.307岁。超过一半的受访者(53%)来自15-25岁年龄组。大多数受访者(97%)识字。56%的受访者对产科危险信号有足够的了解,27%的受访者有适度的了解,很少有受访者(17%)有不足的了解。知识与所选的可变年龄、教育状况、妊娠、妊娠周和ANC就诊次数没有任何显著关系。因此得出的结论是,从ANC就诊之初,整个孕妇就需要一些干预措施来提高对产科危险信号的认识。按照世界卫生组织的建议,非国大的访问重点应超过8次。
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引用次数: 0
Study on adverse effects of COVISHIELD vaccine among hospital employees of Nepal Medical College and Teaching Hospital 尼泊尔医学院和教学医院员工接种新冠肺炎疫苗的不良反应研究
Pub Date : 2022-06-27 DOI: 10.3126/nmcj.v24i2.46024
L. Tuladhar, A. Khapung, N. Dhakal, D. Regmi, A. Sapkota, Jyotsana Pokharel
Nepal government provided COVISHIELD vaccine first to the hospital employees and other front liners in January 2021. The objective of our study was to observe the adverse effects of the COVISHIELD among hospital employees of Nepal Medical College and Teaching Hospital (NMCTH). This was a descriptive cross-sectional study conducted from March to August 2021. The study was commenced after obtaining ethical clearance from the Institutional Review Committee of NMCTH. Self-reported socio-demographic details and symptomatic adverse effects reported after the first and second dose of COVISHIELD were noted. The data were entered in SPSS 16 and analysed. Out of 436 participants, 360 (82.6%) and 243 (55.7%) had reported adverse effects after the first and second dose of the COVISHIELD respectively. The adverse effects reported following COVISHIELD were common and predictable.
2021年1月,尼泊尔政府首次向医院员工和其他一线人员提供了新冠肺炎疫苗。我们研究的目的是观察COVISHIELD在尼泊尔医学院和教学医院(NMCTH)医院员工中的不良影响。这是一项2021年3月至8月进行的描述性横断面研究。该研究是在获得NMCTH机构审查委员会的伦理批准后开始的。注意到第一剂和第二剂COVISHIELD后报告的自我报告的社会人口学细节和症状不良反应。将数据输入SPSS 16中进行分析。在436名参与者中,360人(82.6%)和243人(55.7%)分别报告了第一剂和第二剂COVISHIELD后的不良反应。COVISHIELD后报告的不良反应是常见且可预测的。
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引用次数: 0
COVID-19: The Pandemic COVID-19:大流行
Pub Date : 2022-04-22 DOI: 10.37080/nmj.183
Bodh Bikram Karki
Coronavirus disease (COVID-19) pandemic had a great impact on all walks of our lives. The global public health of this intensity is the first of its kind to affect education, economics, transportation across the globe. At first, it was havoc. However, we tackled this great stride with social distancing, lockdowns quarantine.  In dire straits of global crisis, we have put our efforts to continuously publish this issue to disseminate medical scientific information and knowledge to the readers. The COVID-19 has infected millions of people globally and claimed numerous lives. It originated in Wuhan city of China, December 2019. It hugely affected worldwide economics, medical educations, treatment strategies, transportations. With its impact on overall health and society, the pandemic has certainly made us think about the “new normal”’. Initially, Nepal was not affected. However, as time passed, Nepal was not spared too. The government stated measures like lockdown which helped in controlling the movements and thus the infection rate. Initially, we had few countable labs equipped with RT-PCR to present the scenario of most of the hospitals having their own lab. There was a time when health care providers as front-liners were deprived of personal protective equipment (PPE). Mask was scared, PPE was not affordable. Fighting COVID 19 without the protective gears is great professionalism and dedication shown by health care workers like doctors, nurses, paramedics in the care of the patients. As COVID 19 took a long turn, knowledge about its course, duration, and treatment strategies were studied in great detail. Today due to the scientific publication of research articles worldwide, healthcare providers are efficiently managing this pandemic. In this grave situation, we have brought this edition of NMJ. We hope the research findings presented in this issue will help the scientific community in better patient care. We are thankful to all authors and reviewers for their contributions to Nepal Medical Journal. We extend our deep gratitude to all those who helped us directly and indirectly in bringing this issue. We wish the same continued support in the future to help us impart scientific knowledge to the medical world. The Editorial BoardJuly 2021, Kathmandu, Nepal
冠状病毒病(COVID-19)大流行对我们的生活产生了巨大影响。这种强度的全球公共卫生是第一次影响到全球的教育、经济和交通。起初,这是一场浩劫。然而,我们通过保持社交距离、封锁和隔离来应对这一大步。在全球危机的严峻形势下,我们努力持续出版本刊,向读者传播医学科学信息和知识。新冠肺炎已在全球感染了数百万人,夺去了无数人的生命。它起源于2019年12月的中国武汉市。它极大地影响了全球经济、医学教育、治疗策略和交通。鉴于疫情对整体健康和社会的影响,我们肯定会思考“新常态”。最初,尼泊尔没有受到影响。然而,随着时间的推移,尼泊尔也未能幸免。政府采取了封锁等措施,帮助控制了人员流动,从而控制了感染率。最初,我们配备RT-PCR的实验室很少,以反映大多数医院都有自己的实验室的情况。曾经有一段时间,作为第一线的卫生保健提供者被剥夺了个人防护装备。口罩被吓到了,个人防护装备买不起。在没有防护装备的情况下抗击COVID - 19是医护人员(如医生、护士、护理人员)在照顾患者时表现出的高度专业精神和奉献精神。随着新冠肺炎疫情的发展,人们对其病程、持续时间和治疗策略进行了详细的研究。今天,由于研究论文在世界范围内的科学发表,医疗保健提供者正在有效地管理这一流行病。在这种严峻的形势下,我们带来了这个版本的NMJ。我们希望本期的研究成果能够帮助科学界更好地护理患者。我们感谢所有作者和审稿人对《尼泊尔医学杂志》的贡献。我们对所有直接和间接帮助我们提出这一问题的人深表感谢。我们希望今后继续得到同样的支持,以帮助我们向医学界传授科学知识。2021年7月,尼泊尔加德满都
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引用次数: 0
Prophylactic Oral Rinse Usage Against Transmission of COVID 19 – A Comprehensive Review 预防性口腔漱口水预防COVID - 19传播的综合综述
Pub Date : 2022-04-22 DOI: 10.37080/nmj.214
Sharika Gopinath, Rithesh Kulal
The recent outbreak of SARS-CoV-2 has engulfed the entire global community, causing widespread public health concerns. Despite various attempts to control the disease’s spread, the epidemic continues to rise due to the community spread of the infection. The oral cavity has been suggested as a possible reservoir for Covid-19 transmission due to the close proximity to the patient during dental treatment, the high generation of aerosols, and the detection of SARS-CoV-2 in saliva. Pre procedural rinsing of mouthwashes have been widely used as a standard measure due to their ability to reduce the number of microorganisms in the oral cavity. Mouthwashes like chlorhexidine gluconate (CHX), cetylpyridinium chloride (CPC), povidone-iodine (PVP-I), and hydrogen peroxide (H2O2) and certain herbal products can be suggested as a possible solution to reduce the viral load in the oral cavity. This paper aims to provide a comprehensive review on certain mouthwashes, their antiviral activity against Covid -19.
最近,新冠肺炎疫情席卷全球,引发了广泛的公共卫生担忧。尽管采取了各种措施来控制疾病的传播,但由于感染在社区传播,该流行病继续上升。口腔被认为是Covid-19可能的传播宿主,因为在牙科治疗期间与患者近距离接触、气溶胶的高生成以及唾液中检测到SARS-CoV-2。由于漱口水能够减少口腔内微生物的数量,因此手术前冲洗漱口水已被广泛用作一种标准措施。漱口水,如葡萄糖酸氯己定(CHX)、氯化十六烷基吡啶(CPC)、聚维酮碘(PVP-I)、过氧化氢(H2O2)和某些草药产品,可以作为减少口腔病毒载量的可能解决方案。本文旨在对几种漱口水及其抗病毒活性进行综述。
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Nepal Medical College journal : NMCJ
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