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Istočno pitanje kroz dalekoistočne oči:Japanski pogledi na ustanke u Hercegovini (1861-1878)
Pub Date : 2021-01-01 DOI: 10.51237/issn.2744-1172.2021.50.77
Nakazava Takuja
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引用次数: 1
Muslimanske rezolucije 1941. U povodu 80 godina od njihovog potpisivanja
Pub Date : 2020-01-01 DOI: 10.51237/issn.2744-1172.2020.49.167
Adnan Jahić
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引用次数: 0
Slučaj "Šimić" i kraj Saveza komunista u Zenici
Pub Date : 2020-01-01 DOI: 10.51237/issn.2744-1172.2020.49.211
Mirza Džananović
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引用次数: 0
Muslimani na stranicama Bosanskohercegovačkih novina (1878-1881) i Sarajevskog lista (1881-1891)
Pub Date : 2020-01-01 DOI: 10.51237/issn.2744-1172.2020.49.89
Mihad Mujanović
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引用次数: 0
Oko kuge u Bosni 1763-1764. godine
Pub Date : 2020-01-01 DOI: 10.51237/issn.2744-1172.2020.49.45
Nenad Filipović
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引用次数: 1
Could Serum Sclerostin Help in Early Assessment and Treatment of Chronic Kidney Disease – Mineral and Bone Disorder? 血清硬化蛋白是否有助于慢性肾脏病-矿物质和骨骼疾病的早期评估和治疗?
Pub Date : 2019-10-01 DOI: 10.2478/prilozi-2019-0024
Andreja Figurek, M. Rroji, G. Spasovski
Corresponding author: Andreja Figurek, Medical faculty, University of Banja Luka, Banja Luka, Republic of Srpska, Bosnia and Herzegovina, e-mail: andrejafigurek@yahoo.com 1 Medical faculty, University of Banja Luka, Banja Luka, Republic of Srpska, Bosnia and Herzegovina 2 Department of Nephrology, University Hospital Center “Mother Tereza”, Tirana, Albania 3 University Department of Nephrology, Medical Faculty, University of Skopje, Skopje, R. N. Macedonia Andreja Figurek1, Merita Rroji2, Goce Spasovski3 COULD SERUM SCLEROSTIN HELP IN EARLY ASSESSMENT AND TREATMENT OF CHRONIC KIDNEY DISEASE – MINERAL AND BONE DISORDER?
通讯作者:Andreja Figurek,波斯尼亚和黑塞哥维那斯普斯卡共和国巴尼亚卢卡巴尼亚卢卡大学医学院,电子邮件:andrejafigurek@yahoo.com 1波斯尼亚和黑塞哥维那塞族共和国巴尼亚卢卡大学医学院2阿尔巴尼亚地拉那大学医院中心“特雷扎母亲”肾病学系3马其顿共和国斯科普里大学医学院肾病学系Andreja figure1, Merita Rroji2, Goce Spasovski3血清SCLEROSTIN是否有助于慢性肾脏疾病-矿物质和骨骼疾病的早期评估和治疗?
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引用次数: 0
Evaluation of Clinical, Laboratory and Treatment Modalities in C3 Glomerulopathy: Single Center Experience 评价C3肾小球病变的临床、实验室和治疗方式:单中心经验
Pub Date : 2019-10-01 DOI: 10.2478/prilozi-2019-0010
H. H. Yeter, Erdem Sütiçen, B. Korucu, Ö. Helvacı, Burak Özbaş, I. Gönül, Ülver Derici, T. Arınsoy, G. Güz
Abstract Background/aim: C3 glomerulopathy (C3GP) defines a rare group of glomerulonephritis (GN), which could lead to end stage renal disease (ESRD). Histopathologic features of the disease have yet to be defined and the prognostic factors and optimal treatment are not fully known. The purpose of this study was to determine the demographic, histological change, treatment modalities and outcomes among patients with C3GP. Material and method: This retrospective observational study was conducted in the Department of Nephrology, Gazi University, Ankara, from 2013 to 2017. All patients with kidney biopsies fulfilling the criteria for C3GP were included in the study. Results: Twenty-four patients with C3GP (50% male and of middle age - 43 years old) were enrolled in this study. 21% (5/24) patients developed ESRD. Renal biopsy findings such as crescent formation, glomerulo-sclerosis and tubular atrophy were similar in patients with ESRD, when compared to patients who did not develop ESRD. The treatment modalities of the patients were examined in two groups as MMF based and non-MMF based. The difference in the preservation of eGFR did not reach statistical significance between these two groups. The success rate of complete remission was similar between both groups. Serum creatinine levels >2.3 mg/dl at admission and need for renal replacement treatment (RRT) were associated with decreased renal survival. Conclusion: MMF based or non-MMF based treatments have similar efficacy in C3GP. Serum creatinine level higher than 2.3 mg/dl at the time of diagnosis and need for RRT during admission are a strong predictor of ESRD with high sensitivity and specificity.
背景/目的:C3肾小球病变(C3GP)是一种罕见的肾小球肾炎(GN),可导致终末期肾病(ESRD)。该疾病的组织病理学特征尚未明确,预后因素和最佳治疗方法尚不完全清楚。本研究的目的是确定C3GP患者的人口统计学、组织学变化、治疗方式和结局。材料和方法:本回顾性观察性研究于2013年至2017年在安卡拉加齐大学肾脏学系进行。所有肾活检符合C3GP标准的患者都被纳入研究。结果:24例C3GP患者(50%为男性,年龄在中年- 43岁)被纳入本研究。21%(5/24)的患者发展为ESRD。与未发生ESRD的患者相比,ESRD患者的肾活检结果(如新月形成、肾小球硬化和肾小管萎缩)相似。将患者的治疗方式分为MMF为主和非MMF为主两组。两组间eGFR保存差异无统计学意义。两组患者完全缓解的成功率相似。入院时血清肌酐水平>2.3 mg/dl和需要肾脏替代治疗(RRT)与肾脏生存降低相关。结论:MMF与非MMF治疗C3GP疗效相近。诊断时血清肌酐水平高于2.3 mg/dl和入院时需要RRT是ESRD的强预测因子,具有高敏感性和特异性。
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引用次数: 1
Identification of Periopathogenes from Dental Plaque in Periodontal Patients with PCR Technique and Their Association with Composite Interleukin-1 Genotype PCR技术鉴定牙周患者牙菌斑周围病原菌及其与白细胞介素-1复合基因型的关系
Pub Date : 2019-10-01 DOI: 10.2478/prilozi-2019-0019
A. Stojanovska, Saska Todoroska, M. Popovska, Ilijana Muratovska, Linda Zendeli Bedzeti
Abstract Introduction: The present study aimed to assess the presence of main types of microorganisms involved in the aetiopathogenesis of chronic periodontitis with PCR technique and determinates the presence of composite IL-1 genotype and their associations with founded bacteria. Material and method: The examined group was consisted from 20 subjects with diagnosed chronic periodontitis and 20 healthy control without periodontitis. Clinical parameters like gingival index (GI), plaque index (PI), bleeding on probing (BOP), periodontal pocket depth (PPD) and clinical attachment lost (CAL) were determinates. Subgingival dental plaque was collected using a sterilized paper point. We used Parodontose Plus test, reverse hybridization kit, for the detection of periodontal marker bacteria, as well as for the detection of composite Interleukin -1 Genotype Results: The most present bacterial species detected from subgingival dental plaque was Treponema denticola and Porfiromonas gingivalis which was present in 65% of examined patients. In relation to the presence of positive genotype in patients, there was no significant difference between the test and control group for p> 0.05 (p = 1.00). For χ2=8,17 (p=0,06, p<0,05) there is an association between Prevotella intermedia, and composite genotype. Between positive genotype and analyzed bacterial species A. actinomycetem comitans for p> 0.05 (p = 1.00), P. gingivalis for p> 0.05 (p = 0.16), T. Forsythia for p> 0.05 (p = 0.20), T. Denticola for p> 0.05 (p = 0.64) no association was found. Conclusion. This investigations confirmed the strong association of these five examined periopathogenes with periodontitis.
摘要:本研究旨在利用PCR技术评估参与慢性牙周炎病原发生的主要微生物类型的存在,并确定复合IL-1基因型的存在及其与所发现细菌的关系。材料与方法:试验组为诊断为慢性牙周炎的20例和未患牙周炎的健康对照20例。测定牙龈指数(GI)、菌斑指数(PI)、探诊出血(BOP)、牙周袋深度(PPD)、临床附着丧失(CAL)等临床参数。龈下牙菌斑用消毒纸尖收集。结果:龈下牙菌斑中检出最多的菌种是密螺旋体(Treponema denticola)和牙龈卟罗单胞菌(Porfiromonas gingivalis), 65%的被检患者检出。在患者中存在阳性基因型方面,试验组与对照组比较p> 0.05 (p = 1.00),差异无统计学意义。χ2=8,17 (p=0,06, p= 0.05 (p= 1.00), p> 0.05 (p= 0.16), p> 0.05 (p= 0.20), p> 0.05 (p= 0.64)均无相关性。结论。这项调查证实了这五种被检查的周围病原体与牙周炎的密切联系。
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引用次数: 2
A Rare Case of Superior Gluteal Artery Pseudo Aneurysm after Blunt Trauma 钝性创伤后臀上动脉假性动脉瘤1例
Pub Date : 2019-10-01 DOI: 10.2478/prilozi-2019-0020
Sime Trpeski, Marija Mihajlova Ilieva, Nina Apostolovska, A. Andonovski, Andreja Gavrilovski, N. Pop-Jordanova
Abstract Prevailing over in rotationally unstable pelvic fractures, acetabular fractures or hip dislocations, superior gluteal artery pseudo aneurysm imperceptibly could be found after blunt force trauma of the pelvic region. We present a case of superior gluteal artery pseudo aneurysm after blunt force trauma that became gradually symptomatic in two months following the prime malevolence. Non-resolving gluteal hematoma presented two months after the incident, disregarding standard treatment methods led the diagnosis to plausible entity of pseudo aneurysm. Standard protocol was followed. CT angiography was indicated and it confirmed the suspected diagnosis. Upon indication a treatment plan was established with correspondent angioembolization of the pathologic substrate. Pseudo aneurism of the superior gluteal artery should be considered as differential diagnosis for unexplained hematomas in the posterior pelvic region following a trauma regardless of its nature.
臀上动脉假性动脉瘤常见于旋转不稳定型骨盆骨折、髋臼骨折或髋关节脱位中,在骨盆钝力损伤后可在不知不觉中发现。我们提出一个病例的臀上动脉假性动脉瘤钝力创伤后,逐渐成为症状在两个月后,主要的恶性。未解决的臀血肿出现两个月后的事件,无视标准的治疗方法导致诊断似是假动脉瘤的实体。遵循标准程序。CT血管造影证实了疑似诊断。根据适应症,制定了相应的病理基质血管栓塞治疗计划。对于创伤后骨盆区不明原因血肿,无论其性质如何,臀上动脉假性动脉瘤都应被视为鉴别诊断。
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引用次数: 0
Association of Systemic Inflammatory Response Syndrome with Bacteremia in Patients with Sepsis 脓毒症患者全身炎症反应综合征与菌血症的关系
Pub Date : 2019-10-01 DOI: 10.2478/prilozi-2019-0014
K. Grozdanovski, Zvonko Milenkovikj, I. Demiri, K. Spasovska, M. Cvetanovska, Goran Rangelov, Velimir Saveski, B. Grozdanovska
Abstract The aim of this study was to evaluate the usability of systemic inflammatory response syndrome (SIRS) and commonly used biochemical parameters as predictors for positive blood culture in patients with sepsis. The study included 313 patients aged ≥18 years with severe sepsis and septic shock consecutively admitted in the Intensive Care Unit (ICU) of the University Clinic for Infectious Diseases in Skopje, Republic of North Macedonia. The study took place from January 1, 2011 to December 31, 2017. We recorded demographic variables, common laboratory tests, SIRS parameters, site of infection, comorbidities and Sequential Organ Failure Assessment (SOFA) score. Blood cultures were positive in 65 (20.8%) patients with sepsis. Gram-positive bacteria were isolated from 35 (53.8%) patients. From the evaluated variables in this study, only the presence of four SIRS parameters was associated with bacteremia, finding that will help to predict bacteremia and initiate early appropriate therapy in septic patients.
摘要本研究的目的是评估全身性炎症反应综合征(SIRS)和常用生化参数作为脓毒症患者血培养阳性预测指标的可用性。该研究纳入313例年龄≥18岁的严重脓毒症和感染性休克患者,这些患者连续入住北马其顿共和国斯科普里大学传染病诊所重症监护室(ICU)。该研究于2011年1月1日至2017年12月31日进行。我们记录了人口统计学变量、常见实验室检查、SIRS参数、感染部位、合并症和顺序器官衰竭评估(SOFA)评分。65例(20.8%)败血症患者血培养呈阳性。革兰氏阳性菌35例(53.8%)。从本研究评估的变量来看,只有4个SIRS参数的存在与菌血症相关,这将有助于预测脓毒症患者的菌血症,并开始早期适当的治疗。
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