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Medical Image of the Month: Cavitating Pseudomonas aeruginosa Pneumonia 本月医学影像:空化性铜绿假单胞菌肺炎
Pub Date : 2021-11-02 DOI: 10.13175/swjpcc034-21
Grigory Kildaze
No abstract available. Article truncated after 150 words. A 56-year-old woman presented with cough and shortness of breath to hospital. She had a temperature of 39.2°C and had recently completed course of steroids and antibiotics for exacerbation of chronic obstructive pulmonary disease (COPD). She was an active smoker of 15 cigarettes/day for about 40 years. No other past medical history was noted. On examination she had left-sided crepitations and oxygen saturations of 90% on room air. Chest x-ray (CXR) (Fig 1:A) showed features of background emphysema with upper lobe peripheral bullae, larger on the left. Dense left peri-hilar consolidation was also described. SARS-CoV-2 swab was negative. White blood cells (WBC) were raised at 16.9x109/L and C-reactive protein (CRP) at 331 mg/L. The rest of the blood tests were unremarkable. CURB-65 score was zero but treatment was commenced with intravenous (IV) amoxicillin & oral clarithromycin in view of level of CRP and CXR findings. On Day 4 of admission …
没有可用的摘要。文章在150字后被截断。一名56岁女子因咳嗽和呼吸急促被送往医院。她的体温为39.2°C,最近完成了治疗慢性阻塞性肺病(COPD)恶化的类固醇和抗生素疗程。在大约40年的时间里,她每天抽15支烟。未发现其他既往病史。在检查中,她出现了左侧皱纹,房间空气中的氧饱和度为90%。胸部x光片(CXR)(图1:A)显示背景肺气肿的特征,左上叶周围大泡较大。还描述了左肺门周围致密性实变。严重急性呼吸系统综合征冠状病毒2型拭子呈阴性。白细胞(WBC)在16.9x109/L时升高,C反应蛋白(CRP)在331mg/L时升高。其余的血液测试都不起眼。CURB-65评分为零,但考虑到CRP和CXR水平,开始静脉注射阿莫西林和口服克拉霉素治疗。入院第4天…
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引用次数: 0
November 2021 Imaging Case of the Month: Let’s Not Dance the Twist 2021年11月月度影像案例:让我们不要跳舞
Pub Date : 2021-11-01 DOI: 10.13175/swjpcc053-21
P. Panse, M. Gotway
No abstract available. Article truncated after the first 150 words. History of Present Illness: An 82-year-old man presented to his physician for general health maintenance as well as a complaint of persistently poor quality sleep and poor appetite with weight loss. The patient had undergone robotic-assisted radical left nephroureterectomy and cystectomy with pelvic lymph node dissection and urinary diversion for left clear cell renal cell carcinoma (staged T2a, grade 2) and transitional cell carcinoma of the bladder (carcinoma in situ at surgery), approximately 9 months earlier. The patient’s bladder malignancy was initially treated with transurethral resection, with histopathology at that procedure showing high-grade papillary urothelial malignancy with lamina propria invasion, but no muscular invasion; this procedure was followed by formal complete resection approximately 3 months later. The patient’s post-operative course was complicated by significant bleeding which required transfusion of 3 units of blood. He had undergone inferior vena caval filter placement prior to surgery when preoperative testing revealed lower extremity …
没有可用的摘要。文章前150字后被截断。现有疾病史:一名82岁的男子向医生介绍了一般健康维护,并抱怨由于体重减轻,睡眠质量持续不佳,食欲不佳。患者在大约9个月前接受了机器人辅助的左肾输尿管根治术和膀胱切除术,包括盆腔淋巴结清扫和尿路改道治疗左透明细胞肾细胞癌(T2a期,2级)和膀胱移行细胞癌(手术中原位癌)。患者的膀胱恶性肿瘤最初通过经尿道电切术进行治疗,该手术的组织病理学显示高度乳头状尿路上皮恶性肿瘤伴固有层侵犯,但无肌肉侵犯;该手术后约3个月进行了正式的完全切除。患者的术后过程因大量出血而复杂,需要输注3个单位的血液。他在手术前接受了下腔静脉滤器置入术,术前检查显示下肢…
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引用次数: 0
Utility of Endobronchial Valves in a Patient with Bronchopleural Fistula in the Setting of COVID-19 Infection: A Case Report and Brief Review 支气管内瓣膜在新冠肺炎感染中的应用:病例报告和简要回顾
Pub Date : 2021-10-29 DOI: 10.13175/swjpcc046-21
N. Sheikhan, E. Benge, Amanpreet Kaur, J. Hruska, Yi Mcwhorter, Arnold Chung
Patients with COVID-19 pneumonia frequently develop acute respiratory distress syndrome (ARDS), and in severe cases, require invasive mechanical ventilation. One complication that can develop in patients with ARDS who are mechanically ventilated is a bronchopleural fistula (BPF). Although rare, the frequency of BPF in patients with COVID-19 pneumonia is increasingly recognized. Here, we present a 48-year old man with BPF associated with COVID-19 pneumonia. Treatment with a commercial endobronchial valve (EBV) system resulted in reduced air leak allowing for tracheostomy placement. Our case adds to a growing body of evidence suggesting that the presence of COVID-19 pneumonia does not hinder the utility of EBV’s in the treatment of BPF’s.
新冠肺炎肺炎患者经常出现急性呼吸窘迫综合征(ARDS),严重时需要有创机械通气。机械通气的ARDS患者可能出现的一种并发症是支气管胸膜瘘(BPF)。尽管罕见,但新冠肺炎肺炎患者中BPF的频率越来越被认识到。在此,我们介绍了一名患有BPF的48岁男子,该男子与新冠肺炎肺炎相关。使用商用支气管内瓣膜(EBV)系统进行治疗可减少空气泄漏,从而进行气管造口术。我们的病例增加了越来越多的证据,表明新冠肺炎肺炎的存在不会阻碍EBV在BPF治疗中的作用。
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引用次数: 0
Refunds If a Drug Doesn’t Work 药物无效退款
Pub Date : 2021-10-27 DOI: 10.13175/swjpcc050-21
R. Robbins, T. Kummet
No abstract available. Article truncated after 150 words. One aspect of the high cost of healthcare is the cost of new drugs. Cancer drugs have received much of the attention because of their extremely high price (1). For example, crizotinib, used to treat non-small cell lung cancer (NSCLC), costs $19,144 for each month's supply. Pfizer, the manufacturer of crizotinib, has just announced that they are offering a refund if its drug "doesn't work" (2). If crizotinib use is discontinued and documentation of ineffectiveness is provided, Pfizer will refund the out-of-pocket amount that was paid for up to the first three bottles (30-day supply) of crizotinib, up to a maximum of $19,144 for each month's supply, or a total of $57,432. Of course, the cost of care includes more than just a single drug and can be much higher and Pfizer is reimbursing only the drug cost. Although Pfizer claims that its pilot program is a first in the …
没有可用的摘要。文章在150字后被截断。医疗成本高的一个方面是新药的成本。癌症药物因其极高的价格而备受关注。例如,用于治疗癌症(NSCLC)的克唑替尼每月的供应费用为19144美元。克唑替尼的制造商辉瑞公司刚刚宣布,如果其药物“无效”,他们将提供退款(2)。如果停止使用克唑替尼,并提供无效证明文件,辉瑞公司将退还前三瓶(30天供应)克唑替奈的自付金额,每月供应的最高金额为19144美元,总计57432美元。当然,护理费用不仅仅包括一种药物,而且可能要高得多,辉瑞只报销药物费用。尽管辉瑞公司声称其试点项目是世界上第一个…
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引用次数: 0
SWJPCC Associate Editor Featured in Albuquerque Journal SWJPCC副主编阿尔伯克基杂志
Pub Date : 2021-10-25 DOI: 10.13175/swjpcc049-21
R. Robbins
No abstract available. Article truncated after 150 words. Dr. Dona Upson forwarded an article from Sunday’s edition of the Albuquerque Journal featured Michel Boivin, a SWJPCC Associate Editor, in an article titled, “Exhaustion in the ICU: Doctors reflect on state’s nearly 5,000 COVID-19 deaths” (1). Boivin and his wife Teri Heynekamp, a married couple who were many years at the University of New Mexico, shared their thoughts last week on New Mexico nearing 5,000 COVID-19 deaths (Figure 1). Yesterday was Day 587 of the COVID-19 pandemic in New Mexico, just another brief hospital scene amid 19 months of loneliness, fatigue and grief. “We feel exhausted,” Heynekamp said in an interview, “like a type of exhaustion that I’ve never experienced in my life.” Doctors and other health care providers say their workload has hardly let up. Even the arrival of safe, effective vaccines, some doctors say, has provided little relief, introducing a new dynamic instead — the knowledge that most …
没有摘要。文章在150字后被删节。Dona Upson博士转发了周日版《阿尔伯克基杂志》上的一篇文章,其中有SWJPCC副主编Michel Boivin在一篇题为“ICU的衰竭:Boivin和他的妻子Teri Heynekamp是一对在新墨西哥大学工作多年的已婚夫妇,他们上周分享了他们对新墨西哥州近5000例COVID-19死亡病例的看法(图1)。昨天是新墨西哥州COVID-19大流行的第587天,在19个月的孤独、疲劳和悲伤中,这只是又一个短暂的医院场景。“我们感到筋疲力尽,”海内坎普在一次采访中说,“就像我一生中从未经历过的那种精疲力竭。”医生和其他医疗服务提供者表示,他们的工作量几乎没有减轻。一些医生说,即使是安全有效的疫苗的出现,也没有带来多少缓解,反而带来了一种新的动态——人们知道大多数……
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引用次数: 0
Alveolopleural Fistula In COVID-19 Treated with Bronchoscopic Occlusion with a Swan-Ganz Catheter 支气管镜下Swan-Ganz导管闭塞治疗COVID-19患者肺泡胸膜瘘
Pub Date : 2021-10-15 DOI: 10.13175/swjpcc026-21
Nathaniel z Hitt, Aleksey Tagintsev, D. Summerfield, Evan D Schmitz
Pneumothorax and pneumomediastinum are known complications of COVID-19 patients. They have been documented to occur both with and without mechanical ventilation. There are several reports of cases further complicated by alveolopleural or bronchopleural fistulas. However, there are no studies and only a few case reports on the treatment options used for alveolopleural fistulas in COVID-19 patients. To our knowledge, there is only one report of bronchoscopic treatment with endobronchial valves in a COVID-19 patient. We present the case of a 63-year-old male with COVID-19, pneumothorax, and an alveolopleural fistula that was successfully sealed using bronchoscopic occlusion with a Swan-Ganz catheter.
气胸和纵隔气是已知的COVID-19患者并发症。有文献记载,在有无机械通气的情况下均会发生。有几个报告的病例进一步并发肺泡胸膜瘘或支气管胸膜瘘。然而,关于COVID-19患者肺泡胸膜瘘的治疗方案没有研究,只有少数病例报道。据我们所知,在COVID-19患者中只有一例支气管镜下支气管内瓣膜治疗的报道。我们报告了一例63岁男性COVID-19,气胸和肺泡胸膜瘘,通过支气管镜闭塞与Swan-Ganz导管成功密封。
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引用次数: 0
Medical Image of the Month: COVID-19-Associated Pulmonary Aspergillosis in a Post-Liver Transplant Patient 本月医学图像:肝移植后患者与covid -19相关的肺曲霉病
Pub Date : 2021-10-02 DOI: 10.13175/swjpcc029-21
P. Anandajith, Z. Mohamed, D. Balakrishnan, S. Sudhindran
No abstract available. Article truncated after first 150 words. A previously healthy, 48-year-old woman, admitted with a working diagnosis of acute-on-chronic liver failure (Grade III) secondary to an autoimmune etiology, was found to be SARS COV-2 RTPCR positive on routine admission screening. She was initially managed with standard medical care for COVID, including steroids. She required invasive ventilation for worsening encephalopathy and when her antigen test was negative 10 days later, she underwent an urgent liver transplantation. Her preoperative infection screen (culture of blood, bronchoalveolar lavage, urine) was negative and computerized tomography (CT) of the chest was normal (Figure 1). She was extubated on day 3 after liver transplantation. Her recovery was uneventful until the 10th postoperative day when she developed cough and desaturation. A repeat CT chest showed multiple multilobular consolidatory nodules with central breakdown involving both lung (Figure 2). Her bronchoalveolar lavage culture grew Aspergillus fumigatus (azole sensitive) which fulfilled criteria for proven COVID-19 Associated pulmonary aspergillosis …
没有可用的摘要。文章前150字后被截断。一名先前健康的48岁女性,因自身免疫性病因继发的急慢性肝功能衰竭(III级)而入院,在常规入院筛查中被发现为严重急性呼吸系统综合征冠状病毒2型RTPCR阳性。她最初接受了标准的新冠肺炎医疗护理,包括类固醇治疗。由于脑病恶化,她需要有创通气,10天后抗原检测呈阴性,她接受了紧急肝移植。她的术前感染筛查(血液培养、支气管肺泡灌洗、尿液)为阴性,胸部计算机断层扫描(CT)正常(图1)。她在肝移植后第3天拔管。直到术后第10天,她出现咳嗽和不饱和症状,她的恢复才平静下来。重复CT胸部显示多个多叶实性结节,中心破裂累及双肺(图2)。她的支气管肺泡灌洗培养培养培养出烟曲霉(唑敏感),符合证明新冠肺炎相关肺曲霉菌病的标准…
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引用次数: 0
October 2021 Critical Care Case of the Month: Unexpected Post-Operative Shock 2021年10月月度重症病例:意外术后休克
Pub Date : 2021-10-01 DOI: 10.13175/swjpcc041-21
S. Srinivasan, Sooraj Kumar, Benjamin Jarrett, J. Campion
No abstract available. Article truncated after 150 words. History of Present Illness: A 55-year-old man with a past medical history significant for endocarditis secondary to intravenous drug use, osteomyelitis of the right lower extremity was admitted for ankle debridement. Pre-operative assessment revealed no acute illness complaints and no significant findings on physical examination except for the ongoing right lower extremity wound. He did well during the approximate one-hour “incision and drainage of the right lower extremity wound”, but became severely hypotensive just after the removal of the tourniquet placed on his right lower extremity. Soon thereafter he experienced pulseless electrical activity (PEA) cardiac arrest and was intubated with return of spontaneous circulation being achieved rapidly after the addition of vasopressors. He remained intubated and on pressors when transferred to the intensive care unit for further management. PMH, PSH, SH, and FH: • S/P Right lower extremity incision and drainage for suspected osteomyelitis as above • Distant history of endocarditis related …
没有摘要。文章在150字后被删节。现病史:55岁男性,既往有明显的静脉吸毒继发心内膜炎病史,右下肢骨髓炎,因踝关节清创入院。术前评估显示无急性疾病主诉,体检无明显发现,除了右下肢伤口。在大约一个小时的“右下肢伤口切开引流”过程中,他情况良好,但在取下右下肢止血带后,他出现了严重的低血压。此后不久,他经历了无脉性电活动(PEA)心脏骤停,并在加入血管加压剂后迅速恢复了自发循环。当他转到重症监护室接受进一步治疗时,他仍然插管并使用加压器。PMH, PSH, SH和FH:•S/P右下肢切口和引流疑似骨髓炎如上述•远史心内膜炎相关…
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引用次数: 0
Medical Image of the Month: Stercoral Colitis 本月医学影像:珊瑚性结肠炎
Pub Date : 2021-09-02 DOI: 10.13175/swjpcc027-21
Kirstin H. Peters, A. Gibbs, J. Campion
No abstract available. Article truncated after 150 words. A 78-year-old- man with cerebral palsy requiring an in-home caregiver presented to the emergency room in hypovolemic shock post-sudden cardiac arrest in the setting of hematemesis. The caregiver noticed the patient become unresponsive after having one episode of bright red emesis. EMS arrived and found the patient to be pulseless and performed three rounds of CPR and gave 1 mg of epinephrine before return of spontaneous circulation was obtained. The caregiver reported the patient had been complaining of diarrhea for the past few days after being started on magnesium citrate for constipation by his PCP. In the ED patient was intubated, sedated, and started on pressors due to undifferentiated shock. CT abdomen pelvis demonstrated diffuse dilation of the colon with massive stool burden and markedly distended rectum with impacted stool and circumferential rectal wall thickening consistent with stercoral colitis (Figures 1 and 2). In addition, there was a large hiatal …
没有可用的摘要。文章在150字后被截断。一位78岁的脑瘫患者在吐血的情况下心脏骤停后出现低血容量性休克,需要在家照顾。护理人员注意到患者在出现一次鲜红色呕吐后变得没有反应。EMS赶到后发现患者没有脉搏,进行了三轮心肺复苏术,并在恢复自主循环前给予1毫克肾上腺素。护理人员报告说,患者在PCP开始服用柠檬酸镁治疗便秘后,在过去几天里一直抱怨腹泻。在ED中,患者因未分化的休克而插管、镇静并开始服用加压药。CT腹部-骨盆显示结肠弥漫性扩张伴大量粪便负担,直肠明显扩张伴阻生粪便,直肠周壁增厚,与粪珊瑚性结肠炎一致(图1和图2)。此外,还有一个很大的中断…
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引用次数: 0
September 2021 Pulmonary Case of the Month: A 45­-Year-Old Woman with Multiple Lung Cysts 本月肺病例:一名45岁女性多发性肺囊肿
Pub Date : 2021-09-01 DOI: 10.13175/swjpcc036-21
L. Wesselius
No abstract available. Article truncated after the first 150 words. History of Present Illness A 45-year-old woman presented with increasing dyspnea on exertion and a history of recurrent pneumothoraces. In March 2018 she had laparoscopic ovarian cyst removal and noted some subsequent shortness of breath. In August 2018 she developed a right pneumothorax requiring chest tube placement. In September 2018 she had recurrent right pneumothorax and had video-assisted thoracoscopic surgery (VATS) with a right pleurodesis. The operative note from the outside VATS indicates a RUL bleb was removed and a wedge biopsy was done from posterior segment of the RUL. Pathology from the wedge biopsy reported “minimal emphysematous disease without other diagnostic abnormality”. She continued to be short of breath after the operation. PMH, SH, and FH • In 1975 she reportedly had pulmonary tuberculosis. • In 2018 the pneumothoraces, pleurodesis and the right ovarian cyst resection noted above. She is a never smoker and has no family history…
没有可用的摘要。文章前150字后被截断。现有疾病史一名45岁女性,表现为用力时呼吸困难加剧,并有复发性胸闷病史。2018年3月,她进行了腹腔镜卵巢囊肿切除术,随后出现了一些呼吸急促。2018年8月,她出现右侧胸腔积液,需要放置胸管。2018年9月,她再次出现右侧胸腔积液,并接受了电视胸腔镜手术(VATS)和右侧胸膜固定术。来自外部VATS的手术记录表明,切除了RUL水泡,并从RUL后部进行了楔形活检。楔形活检的病理学报告“轻微肺气肿,无其他诊断异常”。手术后她仍然呼吸急促。PMH、SH和FH•据报道,1975年她患有肺结核。•2018年,上文提到了胸腔积液、胸膜固定术和右卵巢囊肿切除术。她从不吸烟,也没有家族史…
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引用次数: 0
期刊
Southwest journal of pulmonary & critical care
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