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WHO Ear and Hearing Disorders Survey in four provinces in China 世卫组织在中国四省的耳部和听力障碍调查
Pub Date : 2011-11-14 DOI: 10.3109/1651386X.2011.631285
X. Bu, Cheng Liu, G. Xing, Ling Zhou, Chuanyu Liang, Yunzhan Zheng, Juang Meng, Youqin Wang, Chong-xuan Yang, Yuqing Liu, B. Du, Yan Zhang, Bo Du
Abstract Objective: To investigate the population based prevalence of ear diseases and hearing impairment in Jiangsu, Sichuan, Guizhou and Jilin Provinces in China, develop strategies to provide scientific data for the global database and to draw up prevention and intervention strategies. Methods: Using the WHO Ear and Hearing Disorders Survey Protocol and the probability proportion to size (PPS) sampling technique, 30,733 residents were targeted for investigation in 150 clusters in four provinces. Every subject had an ear examination and pure tone audiometry. Definitions of disabling hearing loss and the classification of hearing impairment used were in accordance with WHO recommendations. Results: Among 30,733 targeted residents, 29,246 individuals (95.2%) participated in the survey. One thousand, three hundred and sixty individuals (4.4%) were absent; 127 individuals (0.4%) refused. The prevalences of hearing impairment and disabling hearing impairment were 14.2% and 5.2% of investigated individuals, respectively: 9.1% of the sample had a mild hearing loss, 3.8% a moderate degree of hearing loss, 1.1% a severe and 0.3% a profound hearing loss. Using data from the fifth population census in China (2000), we calculated the standardized rates of hearing impairment and hearing disability in our study to be 11.7% and 4.4%, respectively. There was a significant difference in the prevalence between males and females, urban and rural dwellers, as well as for different ages. The prevalence of ear diseases was 6.5% of investigated individuals: the standardized rate was 5.9%; 0.2% of investigated individuals had auricle malformation, 2.2% impacted cerumen, 0.2% otitis externa, 0.3% fungi, 0.1% foreign body, 0.1% acute otitis media, 0.9% chronic suppurative otitis media, 1.8% serous otitis media and 1.3% dry perforation of tympanic membrane. Overall, 8.0% of investigated persons were assessed to be likely to benefit from hearing aids, while 4.0% of persons needed medication, 0.1% language/speech rehabilitation, 1.5% non-urgent surgery and 0.9% other treatment. Conclusions: The high prevalence of hearing impairment and disability is a heavy burden on social development and also hinders normal family life. The government and society as a whole should show more concern about these problems. Strategies for prevention and intervention should be focused on less developed regions, rural areas, aging people and non-infectious conditions. Hearing aids services, medication, professional education and training are particularly important in developing countries.
摘要目的:了解中国江苏、四川、贵州和吉林四省人群耳部疾病和听力障碍患病率,为全球数据库提供科学数据,制定预防和干预策略。方法:采用世界卫生组织耳和听力障碍调查方案和概率比例抽样(PPS)方法,在4个省150个聚集区对30,733名居民进行调查。每个受试者都进行了耳部检查和纯音听力测定。致残性听力损失的定义和所使用的听力障碍分类符合世卫组织的建议。结果:在调查对象30,733人中,有29,246人(95.2%)参与了调查。16360人(4.4%)缺席;127人(0.4%)拒绝。听力障碍和致残性听力障碍患病率分别为14.2%和5.2%,其中轻度听力损失占9.1%,中度听力损失占3.8%,重度听力损失占1.1%,重度听力损失占0.3%。根据中国第五次人口普查(2000年)的数据,我们计算出本研究中听力损伤和听力残疾的标准化率分别为11.7%和4.4%。男性和女性、城市和农村居民以及不同年龄之间的患病率存在显著差异。耳部疾病患病率为6.5%,标准化率为5.9%;0.2%的调查对象有耳廓畸形、2.2%的耳垢、0.2%的外耳炎、0.3%的真菌、0.1%的异物、0.1%的急性中耳炎、0.9%的慢性化脓性中耳炎、1.8%的浆液性中耳炎和1.3%的鼓膜干穿孔。总体而言,8.0%的被调查者被评估为可能受益于助听器,而4.0%的人需要药物治疗,0.1%的人需要语言/言语康复,1.5%的人需要非紧急手术,0.9%的人需要其他治疗。结论:听力障碍和残疾的高发是社会发展的沉重负担,也阻碍了正常的家庭生活。政府和整个社会都应该更加关注这些问题。预防和干预战略应侧重于欠发达地区、农村地区、老年人和非传染性疾病。助听器服务、药物、专业教育和培训在发展中国家尤为重要。
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引用次数: 11
Central vestibular compensation: Update 中央前庭代偿:更新
Pub Date : 2011-11-14 DOI: 10.3109/1651386X.2011.626151
Hesham Samy, M. El-Badry
Abstract Vestibular compensation involves multiple, parallel plastic routes at various locations in the brain. Experimental studies propose that adaptive changes in the sensitivity of central vestibular system to the inhibitory neurotransmitters GABA and glycine, changes in the electrophysiological excitability of vestibular neurons, changes in the inhibitory control of the brainstem, vestibular networks by the cerebellum, gliosis and neurogenesis in the vestibular nuclei, and activity-dependent reorganization of the synaptic network of the vestibular pathways, are mechanisms involved in central compensation.
前庭代偿涉及大脑不同位置的多个平行的可塑性通路。实验研究认为,前庭中枢系统对抑制性神经递质GABA和甘氨酸敏感性的适应性变化,前庭神经元电生理兴奋性的变化,脑干对前庭网络的抑制性控制的变化,小脑的前庭网络,前庭核的胶质增生和神经发生,以及前庭通路突触网络的活动依赖性重组。是否有机制参与中枢补偿。
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引用次数: 0
Assessment of Hyperacusis in Egyptian patients: Evaluation of the Arabic version of the Khalfa questionnaire 埃及患者听觉亢进的评估:Khalfa问卷阿拉伯语版的评估
Pub Date : 2011-11-14 DOI: 10.3109/1651386X.2011.624684
M. Shabana, M. Selim, Amr El Refaie, Tarek El Dessouky, R. Soliman
Abstract Objectives: Hyperacusis appears to be a subjective phenomenon, which is not easily defined or quantified by objective measurements. The primary aim of this work was to evaluate the Arabic version of the Khalfa questionnaire for hyperacusis on a sample of normal hearing Egyptians complaining of hyperacusis. The secondary aim was to compare the audiological criteria of this group of hyperacusis patients (with or without tinnitus) with a control group of similar age and gender. Study design: The study group comprised 60 adult patients (age range 19–45 years) having normal hearing and complaining of hyperacusis with or without tinnitus. The control group comprised 20 normal hearing age and gender-matched individuals. All patients were subjected to full history-taking, otological examination, pure tone audiometry, immittance audiometry, uncomfortable loudness levels (ULLs) assessment, a transient evoked otoacoustic emissions (TEOAEs) test and, in addition, to the Arabic version of the Khalfa hyperacusis questionnaire. Results: The uncomfortable loudness levels indicated a markedly contracted dynamic range in the hyperacusis group, with the majority of individuals showing ULLs less than 90dB HL. Hyperacusis patients with tinnitus showed significantly lower TEOAEs amplitudes, with overall echo level and reproducibility percent lower than for hyperacusis patients without tinnitus or for the control group. Hyperacusis patients had higher means of total, attentional, social, and emotional scores on the Khalfa questionnaire compared to the control group. The emotional parameter of the questionnaire had the highest score for the hyperacusis patients. Both the emotional and attentional dimension scores were higher in females, while attentional scores were higher for males. The total and social dimensions were affected by age. Conclusions: The emotional impact of noise exposure was more severe than the attentional and social impact in hyperacusis patients. There was a gender difference evident in the results of the Khalfa questionnaire in hyperacusis patients. The Arabic version of the Khalfa hyperacusis questionnaire seems to be a fairly effective tool for the assessment of hyperacusis patients.
摘要目的:听觉亢进似乎是一种主观现象,不容易通过客观测量来定义或量化。这项工作的主要目的是评估阿拉伯语版本的哈利法调查问卷的听力正常的埃及人抱怨听力亢进的样本。第二个目的是比较这组耳鸣患者(伴有或不伴有耳鸣)与年龄和性别相似的对照组的听力学标准。研究设计:研究组包括60名成年患者(年龄范围19-45岁),听力正常,主诉听觉亢进伴或不伴耳鸣。对照组由20名听力正常且性别匹配的个体组成。所有患者都接受了完整的病史记录、耳科检查、纯音听力学、听力听力学、不舒服响度水平(ULLs)评估、瞬态诱发耳声发射(teoae)测试,此外,还接受了阿拉伯语版本的Khalfa超听问卷。结果:不舒服的响度水平表明,超听组的动态范围明显缩小,大多数个体的ull小于90dB HL。伴有耳鸣的耳聋患者teoae振幅明显低于无耳鸣的耳聋患者或对照组,其总体回声水平和再现率均低于对照组。与对照组相比,听力亢进患者在Khalfa问卷上的总分、注意力、社交和情绪得分较高。听力亢进患者的情绪参数得分最高。女性的情感和注意维度得分较高,而男性的注意维度得分较高。总体和社会维度受年龄的影响。结论:噪声暴露对耳聋患者的情绪影响大于注意和社会影响。在听觉亢进患者的Khalfa问卷调查结果有明显的性别差异。阿拉伯语版本的Khalfa听力亢进问卷似乎是一个相当有效的工具,为听力亢进患者的评估。
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引用次数: 6
Auditory and vestibular findings in patients with vestibular migraine 前庭偏头痛患者的听觉和前庭表现
Pub Date : 2011-08-23 DOI: 10.3109/1651386X.2011.607248
Yasser Nafie, M. Friedman, M. Hamid
Abstract Objective: We aimed to report audiological and vestibular test results in patients with vestibular migraine (VM). We used a retrospective analysis study design in the setting of a tertiary referral neuro-otology center. Patients and methods: Data from 55 patients with the diagnosis of vestibular migraine were enrolled into the study. Comprehensive audiometry, electronystagmography (ENG) and vestibular myogenic evoked potentials (VEMP) were the interventions and main outcome measures were the degree and profile of hearing loss, speech discrimination, oculomotor gaze, saccades and pursuit abnormalities, as well as the presence of spontaneous, post head-shake and positional nystagmus. We also measured the caloric response peak slow phase velocity, asymmetry, failure of fixation suppression, and VEMP p12-n23 latency response. Results: Sensorineural hearing loss was present in 71% (39/55) of patients; 53% (29/55) had bilateral symmetrical loss, 9% (5/55) had bilateral asymmetrical loss and 9% (5/55) had unilateral loss. The pattern of hearing loss was flat in 44% (24/55) of patients, low frequency in 3% (2/55) and high frequency in 24% (13/55). The degree of hearing loss was 10–25dB HL in 62% (34/55) of patients and >25dB HL in 9% (5/55). Word discrimination scores were ≥90% in 97% (53/55) of patients and <90% (84–88%) in only 3% (2/55) of patients. Abnormal vestibular findings were present in 87% (48/55). Oculomotor saccades, pursuit, and gaze tests were normal in all patients. Abnormal nystagmus was present in 58% (32/55) of patients; 15% (8/55) had spontaneous nystagmus, 31% (17/55) had post head-shake nystagmus, and 36% (20/55) had non-paroxysmal positional nystagmus. None of the patients had benign paroxysmal positional nystagmus. Caloric responses were normal and symmetrical in 57% (31/55) of patients and showed unilateral weakness in 33% (18/55) of patients. No bilateral weakness was present. Caloric hyperactivity (caloric response >40°/s) was present in 10% (6/55) of patients. All patients showed normal fixation suppression index. VEMP response (p13n23) was present in 66% (33/50) of patients with normal latency and absent in 34% (17/55) of patients. Conclusions: Sixty-two percent (34/55) of the vestibular migraine patients in this study had sensorineural hearing loss (>10–25dB HL), 58% (32/55) abnormal nystagmus, 10% (6/55) hyperactive caloric response, 33% (18/55) caloric asymmetry and 34% (17/55) absent VEMP. The patients in this study did not have central vestibular abnormalities.
摘要目的:报道前庭偏头痛(VM)患者的听力学和前庭测试结果。我们在三级转诊神经耳科中心采用回顾性分析研究设计。患者和方法:来自55名诊断为前庭偏头痛的患者的数据被纳入研究。综合听力学、眼震电图(ENG)和前庭肌源性诱发电位(VEMP)是干预措施,主要结局指标是听力损失的程度和特征、言语辨别、动眼性凝视、扫视和追求异常,以及自发性、后摇头和位置性眼震的存在。我们还测量了热反应峰慢相速度、不对称性、固定抑制失败和VEMP p12-n23潜伏期反应。结果:71%(39/55)的患者存在感音神经性听力损失;53%(29/55)为双侧对称损失,9%(5/55)为双侧不对称损失,9%(5/55)为单侧损失。44%(24/55)的患者听力损失模式平坦,3%(2/55)为低频,24%(13/55)为高频。62%(34/55)的患者听力损失为10-25dB HL, 9%(5/55)的患者听力损失>25dB HL。97%(53/55)患者的辨字评分≥90%,10%(6/55)患者的辨字评分为40°/s。所有患者的固定抑制指数均正常。66%(33/50)潜伏期正常的患者有VEMP反应(p13n23), 34%(17/55)患者无VEMP反应。结论:本研究中,62%(34/55)的前庭偏头痛患者存在感音神经性听力损失(> 10-25dB HL), 58%(32/55)的眼球震颤异常,10%(6/55)的热量反应过度活跃,33%(18/55)的热量不对称,34%(17/55)的VEMP缺失。本研究的患者没有前庭中枢异常。
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引用次数: 3
Group or individual tinnitus therapy: What matters to participants? 团体或个人耳鸣治疗:对参与者来说什么重要?
Pub Date : 2011-08-23 DOI: 10.3109/1651386X.2011.604470
P. Thompson, H. Pryce, E. Refaie
Abstract Objective: To explore the ‘active ingredient’ of tinnitus therapy groups. Study design: The design was an inductive qualitative study informed by grounded theory. Eight participants, four from a tinnitus group and four from individual therapy with similar content, were invited to discuss their experiences of tinnitus therapy. The interviews were transcribed and analysed using a constant comparative approach. Results: The findings revealed that group experiences facilitate information exchange and social comparison, which facilitates coping. Conclusions: The human dynamics of groups may have an additional therapeutic benefit.
摘要目的:探讨耳鸣治疗组的“有效成分”。研究设计:设计是一项基于扎根理论的归纳定性研究。8名参与者,4名来自耳鸣组,4名来自内容相似的个体治疗,被邀请讨论他们的耳鸣治疗经验。访谈记录和分析采用持续比较的方法。结果:群体经历促进了信息交换和社会比较,从而促进了应对。结论:群体的人体动力学可能具有额外的治疗益处。
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引用次数: 7
Models to represent communication partners within the social networks of people with hearing impairment 代表听障人士社交网络中的交流伙伴的模型
Pub Date : 2011-08-23 DOI: 10.3109/00365521.2011.599228
V. Manchaiah, D. Stephens
Abstract Objective: People with hearing impairment have relatively smaller social networks than their normally hearing peers, and may experience more feelings of loneliness. The effects on the person with hearing impairment (PHI) can also impact on their communication partners (CPs). This report discusses the currently available model representing the CPs within the social network context of the PHI and proposes a new model. Study design: The ‘Communication Rings’ proposed and developed by the Ida Institute is discussed. We believe that this model is too simple to represent the complexity and dynamic nature of the CP's role in the life of the PHI and highlights the need for a new model. Results: We suggest that the model ‘Communication World’ based on the analogy of the solar system, may help overcome some of the problems identified. Clinical examples of how to apply this model and its usefulness in rehabilitation are presented. Conclusions: The expanded model could provide novel information, and provision of a visual representation will help CPs understand the problems of the PHI.
摘要目的:与听力正常的同龄人相比,听力障碍人群的社交网络相对较小,并且可能会感受到更多的孤独感。对听力受损者(PHI)的影响也会影响他们的沟通伙伴(CPs)。本报告讨论了目前在PHI的社会网络环境中表示CPs的可用模型,并提出了一个新模型。研究设计:讨论了由Ida研究所提出和开发的“通信环”。我们认为这个模型过于简单,无法代表CP在PHI生命周期中角色的复杂性和动态性,因此需要一个新的模型。结果:我们建议基于太阳系类比的“通信世界”模型可能有助于克服所发现的一些问题。介绍了如何应用该模型的临床实例及其在康复中的实用性。结论:扩展的模型可以提供新的信息,提供一个可视化的表示将有助于CPs理解PHI的问题。
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引用次数: 3
Mismatch negativity in auditory neuropathy/auditory dys-synchrony 听神经病变/听觉不同步中的错配负性
Pub Date : 2011-08-23 DOI: 10.3109/1651386X.2011.605623
T. Gabr
Abstract Auditory neuropathy/auditory dys-synchrony (AN/AD) is a recently described hearing disorder that has unique pathologies and perceptual consequences. Difficulty in understanding speech is a consistently reported consequence of this type of hearing loss. These patients can detect speech sounds but cannot discriminate what they have heard. Objectives: This work was designed to investigate fine discrimination abilities in these patients and to assess the possibility of there being any abnormalities which might contribute to the difficulty in speech perception. Method: Subjects were classified into 2 groups: control group (GI) composed of 20 normal hearing subjects and the study group (GII) composed of 17 AN/AD patients. All cases were subjected to: full audiological history, otological examination, basic audiological evaluation, Mismatch Negativity (MMN) using tone stimuli in 4 paradigms. Results: MMN response was significantly delayed in AN/AD group when compared to control with some difference between tested frequencies. Conclusion: MMN provided an excellent tool for assessing fine discrimination in AN/AD patients.
听觉神经病变/听觉不同步(AN/AD)是一种最近被描述的听力障碍,具有独特的病理和感知后果。这种类型的听力损失经常导致理解语言的困难。这些病人能察觉到说话的声音,但不能区分他们听到的是什么。目的:本研究旨在探讨这些患者的精细辨别能力,并评估可能导致言语感知困难的任何异常的可能性。方法:将受试者分为两组:对照组(GI) 20例听力正常者和研究组(GII) 17例AN/AD患者。所有病例均接受完整听力学史、耳科检查、基础听力学评估、4种模式下的音调刺激失配负性(MMN)测试。结果:与对照组相比,AN/AD组MMN反应明显延迟,且测试频率之间存在一定差异。结论:MMN是评估an /AD患者精细鉴别的良好工具。
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引用次数: 4
Politzer and the Annamites 波利色和亚南人
Pub Date : 2011-08-23 DOI: 10.3109/1651386X.2011.598706
D. Stephens
Abstract Politzer in his ‘Geschichte der Ohrenheilkunde’ published in 1907 reported on an unusual belief among the Annamites that the ear is inhabited by a small animal which is responsible for hearing, tinnitus and ear wax. The origins of this report are explored and further information presented.
Politzer在1907年出版的《Geschichte der Ohrenheilkunde》中报道了安南人的一个不寻常的信念,即耳朵里住着一种小动物,它负责听力、耳鸣和耳垢。本文探讨了本报告的来源,并提供了进一步的资料。
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引用次数: 0
The impact of sertraline on health-related quality of life in severe refractory tinnitus: A double-blind, randomized, placebo-controlled study 舍曲林对严重难治性耳鸣患者健康相关生活质量的影响:一项双盲、随机、安慰剂对照研究
Pub Date : 2011-05-19 DOI: 10.3109/1651386X.2011.580184
K. Holgers, S. Zöger, J. Svedlund
Abstract Objective: Little is known about the influence of antidepressants on tinnitus patients’ health-related quality of life (HR-QoL). We have addressed this question by investigating the efficacy of sertraline on severe refractory tinnitus. Study design: Seventy-five consecutive patients without socially disabling hearing loss, who fulfilled risk criteria for developing severe refractory tinnitus based on a screening procedure with established validity, were randomly assigned to 16 weeks of placebo (n = 38) or sertraline (n = 37) at a fixed dose (50 mg/day) in a double-blind treatment trial. After completion of the placebo-controlled trial, all patients were offered to continue with sertraline and to participate in another follow-up after 12 weeks. The remaining sertraline group at 16 weeks was studied for a total of 28 weeks treatment. Psychological General Well-Being (PGWB) index served as an indicator of HR-QoL and was administered at baseline before treatment and at 16 and 28 weeks follow-up. Results: The intention-to-treat analysis showed sertraline to be more effective than placebo (p < 0.001) in improving HR-QoL after 16 weeks treatment. The improvement after 16 weeks was maintained at 28 weeks. Conclusion: We conclude that sertraline improves the HR-QoL in severe refractory tinnitus compared to placebo and that improvements in HR-QoL are maintained over time.
摘要目的:抗抑郁药对耳鸣患者健康相关生活质量(HR-QoL)的影响尚不清楚。我们通过调查舍曲林对严重难治性耳鸣的疗效来解决这个问题。研究设计:在一项双盲治疗试验中,连续75例无社交致残性听力损失的患者,符合发生严重难治性耳鸣的风险标准,根据已建立的有效性筛选程序,随机分配到16周的安慰剂(n = 38)或固定剂量(50 mg/天)的舍曲林(n = 37)。安慰剂对照试验完成后,所有患者继续服用舍曲林,并在12周后参加另一次随访。其余舍曲林组在16周时进行了总共28周的治疗。心理一般幸福感(PGWB)指数作为HR-QoL的指标,于治疗前基线及随访16周和28周时进行测量。结果:意向治疗分析显示,在治疗16周后,舍曲林比安慰剂更有效地改善患者的HR-QoL (p < 0.001)。16周后的改善维持在28周。结论:与安慰剂相比,舍曲林改善了严重难治性耳鸣患者的HR-QoL,并且这种改善可以持续一段时间。
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引用次数: 4
Superior semicircular canal dehiscence and lack of the tympano-ossicular system: Favourable functional aspects of a coincidental finding 上半规管破裂和鼓室-听骨系统缺失:巧合发现的有利功能方面
Pub Date : 2011-05-19 DOI: 10.3109/1651386X.2011.559381
A. Pirodda, C. Brandolini, M. C. Raimondi, G. Ferri, G. Modugno
Abstract Objectives: Our objectives were to report the functional conditions of superior semicircular canal dehiscence (SSCD) associated with the post-inflammatory lack of tympano-ossicular system. Methods: A 40-year-old male, initially referred for bilateral ear discharge due to a left cholesteatoma and a right unstable ‘intact bridge’ tympanoplasty, underwent a left open mastoidectomy without a tympano-ossicular reconstruction. Two years later, he had a conversion of the ‘intact bridge’ tympanoplasty into an open mastoidectomy without reconstruction on the right side. Moreover, he had a bilateral SSCD diagnosed by means of vestibular evoked myogenic potentials (VEMPs) and high-resolution computed tomography (HRCT). Results: Combination of the absence of the tympano-ossicular system and SSCD resulted in surprisingly good hearing function. Conclusions: The reported bilateral near-to-normal hearing function outlines the possibility of a favourable outcome deriving from the association of two different adverse conditions. This presents an opportunity for reflection on the pathophysiology of sound transmission, and indicates the usefulness of including the radiological investigation of the bone overlying the superior semicircular canal even when investigating inflammatory middle ear diseases.
摘要目的:我们的目的是报道与炎症后鼓室-听骨系统缺失相关的上半圆形管裂孔(SSCD)的功能状况。方法:一名40岁男性,最初因左侧胆脂瘤和右侧不稳定的“完整桥”鼓室成形术而被转诊为双耳排出,接受了左侧开放式乳突切除术,未进行鼓室-听骨重建。两年后,他接受了“完整桥式”鼓室成形术转化为开放式乳突切除术,右侧没有重建。此外,通过前庭诱发肌源性电位(VEMPs)和高分辨率计算机断层扫描(HRCT),他被诊断为双侧SSCD。结果:鼓室-听骨系统的缺失和SSCD的结合导致了令人惊讶的良好听力功能。结论:报告的双侧听力功能接近正常概述了两种不同不利条件相关的有利结果的可能性。这为声音传播的病理生理学提供了一个反思的机会,并表明即使在调查炎症性中耳疾病时,包括对上半规管上骨的放射学调查也是有用的。
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引用次数: 0
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Audiological medicine
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