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Behavioral consequences of pediatric traumatic brain injury 儿童创伤性脑损伤的行为后果
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.43
G. Prigatano, John B Fulton, Jennifer Wethe
Behavioral problems are common after pediatric traumatic brain injury (TBI), but poorly understood. In this article we review ten common behavioral problems observed in children after TBI and consider the factors that appear to contribute to their expression. Both neurological and non-neurological variables can interact in a complicated way to produce behavioral problems in school-age children following TBI. We conclude with suggestions for the management and treatment of these behavioral problems in a manner that hopefully will reduce parental distress and disruptive behaviors of the child in school.
儿童创伤性脑损伤(TBI)后的行为问题很常见,但人们对其了解甚少。在这篇文章中,我们回顾了在创伤性脑损伤后观察到的十种常见的行为问题,并考虑了导致这些问题表现的因素。神经系统和非神经系统的变量可以以一种复杂的方式相互作用,产生学龄儿童脑外伤后的行为问题。最后,我们提出了管理和治疗这些行为问题的建议,希望能减少父母的痛苦和孩子在学校的破坏性行为。
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引用次数: 10
Pediatric subspecialty shortage: a looming crisis 儿科亚专业短缺:迫在眉睫的危机
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.44
D. Plumley
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引用次数: 2
Pediatric nephrology today 今天的儿科肾病学
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.34
K. Möller, M. Kemper
Pediatric nephrology has been established as an important specialty in the field of pediatrics over the past four decades. In 1976, the German society of Pediatric Nephrology (GPN) was founded (formerly known as APN) and annual spring conferences are an important event in this society. This years focus was congenital nephropathies, kidney and hormones, and dialysis and transplantation. A total of 133 original contributions were presented.
在过去的四十年里,儿科肾脏病学已经成为儿科领域的一个重要专业。1976年,德国儿科肾脏病学会(GPN)成立(前身为APN),每年的春季会议是该学会的重要活动。今年的重点是先天性肾病、肾脏和激素、透析和移植。总共提出了133份原稿。
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引用次数: 0
Treatment-resistant asthma: Options and decision making 难治性哮喘:选择和决策
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.37
Alison Ting, C. Murray
Asthma represents one of the most common chronic conditions affecting children. Effective therapies exist, but some children continue to have treatment-resistant asthma. Management remains a significant challenge and evidence for the treatment of asthma at the severe end of the spectrum is lacking. However, a structured approach to assessment and management can be used to improve patient outcomes. For the minority in whom symptoms persist, further investigations, alternative anti-inflammatory drugs or more novel therapies, such as anti-IgE, may need to be considered and these are best carried out by a specialist pediatric pulmonologist. Further developments in the use of noninvasive biomarkers to help individualize treatment will be helpful in the future treatment of severe asthma.
哮喘是影响儿童最常见的慢性疾病之一。有效的治疗方法已经存在,但一些儿童仍然患有难治性哮喘。管理仍然是一项重大挑战,并且缺乏治疗哮喘严重端的证据。然而,一个结构化的方法来评估和管理可以用来改善病人的结果。对于少数症状持续存在的患者,可能需要考虑进一步的调查,替代抗炎药物或更新颖的治疗方法,如抗ige,这些最好由儿科肺科专家进行。使用无创生物标志物来帮助个体化治疗的进一步发展将有助于未来严重哮喘的治疗。
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引用次数: 0
What does ‘meaningful use’ mean for pediatrics? “有意义的使用”对儿科意味着什么?
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.40
Christoph U. Lehmann, Jennifer Mansour, J. Klein
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引用次数: 2
Magnetic resonance enterography for assessing pediatric Crohn’s disease 磁共振肠造影在评估儿童克罗恩病中的应用
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.39
J. Silverstein, D. Grand, N. LeLeiko
Crohn’s disease is a chronic inflammatory disorder of the GI tract that often presents during childhood and adolescence. Children with Crohn’s disease are often subjected to repeated radiologic examinations throughout the course of their illness, thereby raising great concern over the potential harm of cumulative radiation exposure. Magnetic resonance enterography is a new modality that provides detailed images of the GI tract without exposure to ionizing radiation. This article reviews past methods of bowel imaging, the scope of the problem with regard to radiation exposure, as well as the technical aspects, indications, and current evidence for magnetic resonance enterography in children with Crohn’s disease. Various examples of inflammatory, stricturing and penetrating disease activity are provided.
克罗恩病是一种胃肠道慢性炎症性疾病,通常出现在儿童和青少年时期。患有克罗恩病的儿童在整个患病过程中经常接受反复的放射检查,从而引起人们对累积辐射暴露的潜在危害的极大关注。磁共振肠造影是一种新的方式,提供详细的胃肠道图像,而不暴露于电离辐射。这篇文章回顾了过去的肠道成像方法,辐射暴露问题的范围,以及技术方面,适应症,和目前的证据为克罗恩病儿童的磁共振肠造影。提供了炎症性、狭窄性和穿透性疾病活动的各种实例。
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引用次数: 1
Effect of smoke-free home and workplace policies on second-hand smoke exposure levels in children: an evidence summary. 无烟家庭和工作场所政策对儿童二手烟暴露水平的影响:证据摘要。
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.41
Z. Kabir, H. Alpert, P. Goodman, S. Haw, I. Behm, G. Connolly, Prakash C. Gupta, L. Clancy
Second-hand smoke (SHS) is a major avoidable cause of developmental and respiratory disease and premature death among children worldwide. SHS is a ‘Class A’ carcinogen, and there is no safe level of SHS exposure. Almost 700 million children worldwide are exposed daily to SHS at home. This article reviews and summarizes evidence based on available studies that report on ‘voluntary’ home smoking restrictions and their effects on SHS exposure levels in children aged 0–17 years. All potentially relevant publications within a 10-year period (January 2000–April 2010) were identified (n = 19 full-text articles) through comprehensive database searches. In general, voluntary household smoking restrictions reported a significant reduction in childhood SHS exposure ranging between 20–50% reductions, using both self-reported and biological measures. Mandated comprehensive workplace and enclosed public smoke-free policies also suggested an apparent benefit in some specific pediatric health encounters, namely, decrease...
二手烟是全世界儿童发育和呼吸系统疾病以及过早死亡的主要可避免原因。SHS是一种“a级”致癌物,没有SHS暴露的安全水平。全世界每天有近7亿儿童在家中接触到二手烟。本文回顾并总结了基于现有研究的证据,这些研究报告了“自愿”在家吸烟限制及其对0-17岁儿童二手烟暴露水平的影响。通过综合数据库检索,确定了10年内(2000年1月至2010年4月)所有可能相关的出版物(n = 19篇全文文章)。一般来说,自愿性家庭吸烟限制报告了儿童二手烟暴露的显著减少,使用自我报告和生物测量的减少幅度在20-50%之间。强制性的全面工作场所和封闭的公共场所无烟政策也表明,在某些特定的儿科健康遭遇方面有明显的好处,即减少…
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引用次数: 17
The utility of nasogastric decompression after intestinal surgery in children 儿童肠道手术后鼻胃减压的应用
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.29
D. Ostlie, S. Peter
Evaluation of: Davila-Perez R, Bracho-Blanchet E, Tovilla-Mercado JM et al.: Unnecessary gastric decompression in distal elective bowel anastomoses in children: a randomized study. World J. Surg. 34(5), 947–953 (2010). Although the use of nasogastric decompression after intestinal surgery has been a common practice for decades, there has not been a prospective randomized trial that supports its purported benefits in children. Davila-Perez and colleagues undertook a scientific approach to the use of nasogastric decompression in children undergoing intestinal anastomoses to determine if clinical benefits could be identified. They randomized 60 pediatric patients undergoing intestinal anastomoses to either undergo nasogastric decompression for 5 days or to not have gastric decompression during the postoperative period. The study was designed as an equivalence study, with a goal to demonstrate that there was equivalence between the treatment arms. The results, with the use of sophisticated statistics, support...
Davila-Perez R, Bracho-Blanchet E, Tovilla-Mercado JM等人的评价:儿童远端择期肠吻合器不必要的胃减压:一项随机研究。世界外科杂志,34(5),947-953(2010)。虽然在肠道手术后使用鼻胃减压已经是几十年来的一种常见做法,但还没有一项前瞻性随机试验支持其对儿童的益处。Davila-Perez及其同事采用了一种科学的方法,在接受肠吻合术的儿童中使用鼻胃减压,以确定是否可以确定临床益处。他们随机选择了60名接受肠吻合术的儿童患者,让他们接受5天的鼻胃减压,或者在术后不进行胃减压。该研究被设计为等效性研究,目的是证明治疗组之间存在等效性。通过使用复杂的统计数据,结果支持……
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引用次数: 0
Gastroesophageal reflux disease in the neonatal intensive care unit 新生儿重症监护病房的胃食管反流病
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.38
A. Aceti, L. Corvaglia
Gastroesophageal reflux (GER), commonly diagnosed in preterm infants in neonatal intensive care units (NICUs), is a cause of morbidity and is known to prolong hospital stay. Pharmacological treatment of presumed or proven GER is increasingly being used in NICUs; this attitude is concerning, owing to an association between pharmacological treatment of GER and serious adverse events, which has recently been demonstrated (i.e., ranitidine and necrotizing enterocolitis). Furthermore, a wide variability exists among NICUs in the proportion of infants treated for GER, which suggests a serious lack of evidence in this field. Thus, there is a need to develop safe and effective treatment options for GER in preterm infants is a critical issue for future research.
胃食管反流(GER)常见于新生儿重症监护病房(NICUs)的早产儿,是一种发病原因,已知会延长住院时间。在新生儿重症监护病房中越来越多地使用药物治疗推定或证实的GER;这种态度令人担忧,因为最近已证实,GER的药物治疗与严重不良事件(即雷尼替丁和坏死性小肠结肠炎)之间存在关联。此外,新生儿重症监护室中接受GER治疗的婴儿比例存在很大差异,这表明该领域的证据严重缺乏。因此,开发安全有效的治疗方案来治疗早产儿GER是未来研究的关键问题。
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引用次数: 1
Trichophyton tonsurans: the need for enhanced infection control measures in the pediatric population 小儿毛癣菌:加强感染控制措施的必要性
Pub Date : 2010-08-24 DOI: 10.2217/PHE.10.42
S. Abdel‐Rahman
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引用次数: 2
期刊
Pediatric health
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