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Vascular stiffness relates to the blood pressure response to stair climbing in young adults. 血管僵硬与年轻人爬楼梯时的血压反应有关。
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-01-09 DOI: 10.1097/MBP.0000000000000791
Saryn J Mandak, Xandra Martinez, Mark Rusnak, Matthew M Schubert, Devan R Romero, Deborah L Feairheller

Objective: Cardiovascular disease (CVD) is the leading global cause of death, with elevated blood pressure (BP) in young adults being linked to CVD in adulthood. Pulse wave velocity (PWV) is a noninvasive measure of arterial stiffness, a predictor of CVD, and can be influenced by exercise. Exercise, like stair climbing, improves vascular health and reduces BP. The primary aims of this study were to examine whether the change in BP after a single stair climb is associated with PWV and whether it is associated with 24-h BP averages.

Methods: Fifty-four young adults (23.8 ± 3.56 years) underwent back-to-back sessions of vascular health assessment, a 24-h ambulatory BP (ABP) monitoring, and a single stair climb exercise consisting of 42 steps. Pre- to post-climb BP response was calculated.

Results: Our population was normotensive (119.4/73.7 mmHg) and had an increase in SBP (126.4-138.5 mmHg, P < 0.05) and heart rate (HR) (85.6-94.2 bpm, P < 0.05) with climb. We found an inverse relationship between PWV (5.4 ± 0.85 m/s) and change in SBP with climb (r = -0.340, P = 0.012). We found no relationship between 24-h BP averages and post-stair climb response.

Conclusion: The first to report an inverse relationship between SBP response to exercise and PWV in young adults emphasizes subtle differences in vascular compliance. While the stair climb elicited a significant vascular response, there was no association with 24-h ABP averages. The potential of stair climbing as a practical exercise for assessing vascular health underscores the need for future research.

目的:心血管疾病(CVD)是全球主要的死亡原因,年轻人血压升高与成年后的CVD有关。脉搏波速度(PWV)是动脉硬度的无创测量,是心血管疾病的预测指标,可以受到运动的影响。运动,比如爬楼梯,可以改善血管健康,降低血压。本研究的主要目的是检查单次爬楼梯后的血压变化是否与PWV有关,以及它是否与24小时血压平均值有关。方法:54名年轻成人(23.8±3.56岁)进行了连续的血管健康评估,24小时动态血压(ABP)监测,并进行了42步的单次爬楼梯运动。计算了爬升前后的BP响应。结果:我们的人群血压正常(119.4/73.7 mmHg),收缩压升高(126.4-138.5 mmHg), P结论:首次报道运动和PWV对年轻人收缩压反应的反比关系强调了血管顺应性的细微差异。虽然爬楼梯引起了明显的血管反应,但与24小时平均ABP无关。爬楼梯作为一种评估血管健康的实用运动的潜力强调了未来研究的必要性。
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引用次数: 0
Association of nocturnal hypertension with daytime blood pressure threshold and patient characteristics assessed by home blood pressure monitoring. 通过家庭血压监测评估夜间高血压与日间血压阈值和患者特征的关系。
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-01-09 DOI: 10.1097/MBP.0000000000000790
Tomohide Sato, Satoshi Hoshide, Ryusuke Ae, Kazuomi Kario

Objectives: Nocturnal hypertension, especially with well-controlled daytime blood pressure (BP), has emerged as a significant risk factor for cardiovascular disease. This study investigated its prevalence by morning home BP cut-off values and examined associated patient characteristics using data from the Japan Morning Surge-Home Blood Pressure (J-HOP) study.

Methods: This post hoc analysis included 2675 participants from the J-HOP study who had complete data on nighttime home BP, measured using validated automatic oscillometric devices. Nocturnal hypertension was defined as a nighttime systolic BP greater than or equal to 120 mmHg and diastolic BP greater than or equal to 70 mmHg.

Results: Among the participants, 60.5% had nocturnal hypertension. The proportion of patients with nocturnal hypertension decreased as the cut-off value for morning home BP was lowered: 40.5, 32.1, 23.7, and 14.6% for less than 135/85 mmHg, less than 130/80 mmHg, less than 125/75 mmHg, and less than 120/70 mmHg, respectively. The prevalence of nocturnal hypertension was significantly higher in individuals with diabetes compared with those without, at morning home BP thresholds of less than 135/85 mmHg (48.1 vs. 39.3%; P = 0.03) and less than 130/80 mmHg (41.0 vs. 30.6%; P = 0.01). Individuals taking diuretics had a significantly lower prevalence of nocturnal hypertension compared with those not taking diuretics, at a morning home BP threshold of less than 135/85 mmHg (35.3 vs. 42.9%; P = 0.01).

Conclusion: A considerable number of patients continued to show nocturnal hypertension even at lower morning home BP thresholds. Diabetes may contribute to nocturnal hypertension despite well-controlled morning BP, while diuretic use may help prevent it.

目的:夜间高血压,尤其是控制良好的日间血压(BP),已成为心血管疾病的重要危险因素。本研究通过早晨居家血压临界值调查其患病率,并使用日本晨间手术-居家血压(J-HOP)研究数据检查相关患者特征。方法:这项事后分析包括来自J-HOP研究的2675名参与者,他们有夜间家庭血压的完整数据,使用经过验证的自动振荡测量设备进行测量。夜间高血压定义为夜间收缩压大于等于120mmhg,舒张压大于等于70mmhg。结果:60.5%的参与者有夜间高血压。夜间高血压患者比例随着晨间血压临界值的降低而降低:低于135/85 mmHg、低于130/80 mmHg、低于125/75 mmHg和低于120/70 mmHg的患者比例分别为40.5%、32.1、23.7%和14.6%。夜间高血压的患病率在糖尿病患者中显著高于无糖尿病患者,早晨血压阈值低于135/85 mmHg(48.1比39.3%,P = 0.03)和低于130/80 mmHg(41.0比30.6%,P = 0.01)。服用利尿剂的患者夜间高血压患病率明显低于未服用利尿剂的患者,清晨血压阈值低于135/85 mmHg(35.3比42.9%,P = 0.01)。结论:相当数量的患者即使在较低的早晨血压阈值下仍持续表现出夜间高血压。糖尿病可能导致夜间高血压,尽管早晨血压控制良好,而使用利尿剂可能有助于预防它。
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引用次数: 0
Ambulatory blood pressure and pulse rate patterns in acute coronary syndrome patients underwent percutaneous coronary intervention. 急性冠状动脉综合征患者经皮冠状动脉介入治疗的动态血压和脉搏模式。
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-01-09 DOI: 10.1097/MBP.0000000000000792
Tawithep Leowattana, Supamongkol Phoopattana, Suchat Sricholwattana, Pakawat Krisnangkura, Arthit Wongsoasu, Nattapun Rattanajaruskul, Worawut Rungsangmanoon, Teeranan Angkananard

Objectives: To evaluate 24-h ambulatory systolic blood pressure (BP), diastolic BP, and pulse rate patterns in patients with acute coronary syndrome (ACS) who underwent percutaneous coronary intervention (PCI), and their association with major adverse cardiac events (MACE).

Methods: We conducted a prospective cohort study in ACS patients in who ambulatory BP monitoring was recorded during 2 weeks post-PCI. Clinical and laboratory factors correlated with dipping BP and pulse rate were analyzed by multivariable logistic regression analysis. A Cox proportional hazard model was applied to find the associated factor(s) with their MACE.

Results: We included 141 patients with ST-elevation myocardial infarction (STEMI) ( n  = 47) and non-STEMI ( n  = 94). The average age was 61.7 ± 11.1 years. Most of them are men (63.8%), had non-STEMI (66.7%), and triple vessel disease (51.1%). Upon assessment of nocturnal dipping BP, 22% were dippers, while the others were nondippers and reverse dippers (39.7 and 38.3%, respectively). Nocturnal hypertension, neutrophil-to-lymphocyte, and mean platelet volume were significantly associated with nondippers [adjusted odds ratio: 5.71, 95% confidence interval (CI): 2.51-12.99; 1.29, 95% CI: 1.01-1.63; 1.84, 95% CI: 1.16-2.93, respectively]. Nondipping pulse rate was found in 66.0% with a mean pulse rate of 75.4 ± 10.9 beats per minute (bpm) (awake) and 70.0 ± 11.2 bpm (sleep). Nondipping pulse rate was only found as an independent factor associated with MACE (hazard ratio: 2.69, 95% CI: 1.06-6.86, P  = 0.04).

Conclusion: This study demonstrated a significant association of MACE with nondipping pulse rate in patients with ACS who underwent PCI.

目的:评价急性冠状动脉综合征(ACS)患者行经皮冠状动脉介入治疗(PCI)后24小时动态收缩压(BP)、舒张压(舒张压)和脉搏模式及其与主要心脏不良事件(MACE)的关系。方法:我们对ACS患者进行了一项前瞻性队列研究,这些患者在pci术后2周内记录了动态血压监测。采用多变量logistic回归分析与血压下降和脉搏率相关的临床和实验室因素。应用Cox比例风险模型寻找与MACE相关的因素。结果:我们纳入了141例st段抬高型心肌梗死(STEMI) (n = 47)和非STEMI (n = 94)患者。平均年龄61.7±11.1岁。其中大多数为男性(63.8%),非stemi(66.7%)和三支血管疾病(51.1%)。在评估夜间下沉血压时,22%为下沉者,其余为非下沉者和反向下沉者(分别为39.7%和38.3%)。夜间高血压、中性粒细胞与淋巴细胞的比值和平均血小板体积与不吃水的患者显著相关[校正优势比:5.71,95%可信区间(CI): 2.51-12.99;1.29, 95% ci: 1.01-1.63;1.84, 95% CI: 1.16-2.93]。66.0%患者脉搏无下降,清醒时平均脉搏率为75.4±10.9次/分,睡眠时平均脉搏率为70.0±11.2次/分。不浸脉率是唯一与MACE相关的独立因素(风险比:2.69,95% CI: 1.06 ~ 6.86, P = 0.04)。结论:本研究表明,ACS患者行PCI后MACE与非倾斜脉搏率有显著相关性。
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引用次数: 0
A single session of multijoint exercises induces prolonged hypotension in medicated hypertensive postmenopausal women: a pilot study. 单次多关节运动可诱导绝经后服药高血压妇女持续低血压:一项初步研究。
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-10 DOI: 10.1097/MBP.0000000000000788
José Carlos Tavares Júnior, Luan Morais Azevêdo, Rodrigo Miguel-Dos-Santos, Gilene de Jesus Pereira, Akeline Santos de Almeida, Aluísio Andrade-Lima, Rogério Brandão Wichi

Background: Isometric exercise has emerged as an effective strategy for blood pressure (BP) management, offering potential advantages over traditional exercise modalities; however, evidence regarding its 24-h effects in medicated hypertensive postmenopausal women remains limited.

Objective: This study investigated the effects of a single session of multijoint isometric exercise on 24-h ambulatory hemodynamic variables in medicated hypertensive postmenopausal women.

Methods: In this randomized crossover trial, 10 medicated hypertensive postmenopausal women (59 7 years) completed two experimental sessions: an isometric exercise session and a control session. The isometric exercise consisted of six multijoint exercises (upper and lower limbs), each performed for three sets of 1 min at 30% of 1-repetition maximum, with 2-min rest intervals. The control session involved sitting at rest for an equivalent duration. Following each session, 24-h ambulatory BP monitoring was conducted.

Results: Significant systolic BP reductions were observed following the isometric exercise session compared with the control session at 1 h (P < 0.05), 6 h (P < 0.05), and 24 h (P < 0.05). Diastolic BP was also reduced at 1 h (P < 0.05) and 12 h (P < 0.05). Both awake and asleep periods showed significant BP reductions for systolic and diastolic BP (all, P < 0.05).

Conclusion: A single session of multijoint isometric exercise effectively reduces ambulatory BP over a 24-h period in medicated hypertensive postmenopausal women, including both awake and asleep periods. These findings support the potential clinical utility of isometric exercise as an adjunctive strategy for BP management in this population.

背景:等长运动已成为血压(BP)管理的有效策略,与传统运动方式相比具有潜在优势;然而,关于它对绝经后高血压妇女24小时的影响的证据仍然有限。目的:探讨单次多关节等长运动对绝经后服药高血压妇女24小时动态血流动力学指标的影响。方法:在这项随机交叉试验中,10名绝经后高血压妇女(597岁)完成了两个实验阶段:一个等长运动阶段和一个对照阶段。等长运动包括6个多关节运动(上肢和下肢),每组进行3组,每次1分钟,最多重复30%,休息时间2分钟。对照组则是静坐相同时间。每次疗程后,进行24小时动态血压监测。结果:与对照组相比,等长运动后1 h (P < 0.05)、6 h (P < 0.05)和24 h (P < 0.05)收缩压明显降低。舒张压在1 h (P < 0.05)和12 h也降低(P < 0.05)。清醒和睡眠时收缩压和舒张压均显著降低(均P < 0.05)。结论:单次多关节等长运动可有效降低绝经后服药高血压妇女24小时内的动态血压,包括清醒和睡眠期。这些发现支持了等长运动作为该人群BP管理的辅助策略的潜在临床应用。
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引用次数: 0
Validation of the YuWell YE990 automatic oscillometric blood pressure monitor in mid-to-late pregnancy according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization Common Criteria (AAMI/ESH/ISO 81060-2:2018/Amd.1:2020). 根据医疗器械进步协会/欧洲高血压学会/国际标准化组织通用标准(AAMI/ESH/ISO 81060-2:2018/Amd.1:2020),验证YuWell YE990妊娠中晚期自动示波血压监测仪。
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-09 DOI: 10.1097/MBP.0000000000000787
Xue Du, Xiaoyue Wang, Xuan Li, Tengteng Li, Wenjie Lv, Zongzhi Yin

Background: This study aimed to validate the accuracy of the YuWell YE990 automated oscillometric upper-arm blood pressure (BP) monitor in pregnant adults according to the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization Common Criteria Universal Standard (ISO 81060-2:2018 + Amd.1:2020).

Methods: Participants with normotension, hypertension without proteinuria, or pre-eclampsia were enrolled in this study. BP measurements were performed using a calibrated mercury sphygmomanometer (reference) and a YE990 device (test) following a same-arm sequential protocol conducted by two trained observers.

Results: A total of 46 participants (138 paired readings) were included in the final analysis. For criterion 1 of the standard, the mean difference between the test and reference devices was -2.9 ± 6.9 mmHg for systolic BP (SBP) and 0.0 ± 6.5 mmHg for diastolic BP (DBP), both within the required limits. For criterion 2, the subject-level SDs were 5.6 mmHg for SBP and 5.7 mmHg for DBP, also satisfying the ISO thresholds of 6.30 and 6.95 mmHg, respectively.

Conclusion: YuWell YE990 met all accuracy criteria specified by the ISO 81060-2:2018 + Amd.1:2020 standard and is recommended for clinical use in pregnant populations.

背景:本研究旨在根据医疗器械进展/欧洲高血压学会/国际标准化组织通用标准通用标准(ISO 81060-2:2018 + Amd.1:2020)验证YuWell YE990全自动上臂血压(BP)监测仪在孕妇中的准确性。方法:血压正常、高血压、无蛋白尿或先兆子痫的参与者被纳入本研究。使用校准过的水银血压计(参考)和YE990装置(测试)进行血压测量,遵循由两名训练有素的观察员进行的同臂顺序方案。结果:共有46名参与者(138对读数)被纳入最终分析。对于标准的判据1,试验装置和参考装置之间的平均差异收缩压(SBP)为-2.9±6.9 mmHg,舒张压(DBP)为0.0±6.5 mmHg,均在要求的范围内。对于标准2,受试者水平的SDs分别为收缩压5.6 mmHg和舒张压5.7 mmHg,也分别满足ISO阈值6.30和6.95 mmHg。结论:YuWell YE990符合ISO 81060-2:2018 + Amd.1:2020标准规定的所有准确性标准,推荐孕妇临床使用。
{"title":"Validation of the YuWell YE990 automatic oscillometric blood pressure monitor in mid-to-late pregnancy according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization Common Criteria (AAMI/ESH/ISO 81060-2:2018/Amd.1:2020).","authors":"Xue Du, Xiaoyue Wang, Xuan Li, Tengteng Li, Wenjie Lv, Zongzhi Yin","doi":"10.1097/MBP.0000000000000787","DOIUrl":"https://doi.org/10.1097/MBP.0000000000000787","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to validate the accuracy of the YuWell YE990 automated oscillometric upper-arm blood pressure (BP) monitor in pregnant adults according to the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization Common Criteria Universal Standard (ISO 81060-2:2018 + Amd.1:2020).</p><p><strong>Methods: </strong>Participants with normotension, hypertension without proteinuria, or pre-eclampsia were enrolled in this study. BP measurements were performed using a calibrated mercury sphygmomanometer (reference) and a YE990 device (test) following a same-arm sequential protocol conducted by two trained observers.</p><p><strong>Results: </strong>A total of 46 participants (138 paired readings) were included in the final analysis. For criterion 1 of the standard, the mean difference between the test and reference devices was -2.9 ± 6.9 mmHg for systolic BP (SBP) and 0.0 ± 6.5 mmHg for diastolic BP (DBP), both within the required limits. For criterion 2, the subject-level SDs were 5.6 mmHg for SBP and 5.7 mmHg for DBP, also satisfying the ISO thresholds of 6.30 and 6.95 mmHg, respectively.</p><p><strong>Conclusion: </strong>YuWell YE990 met all accuracy criteria specified by the ISO 81060-2:2018 + Amd.1:2020 standard and is recommended for clinical use in pregnant populations.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145773362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Child weight status and high blood pressure from 6 to 12 years of age: results from the PREDI cohort study. 6至12岁儿童体重状况与高血压:PREDI队列研究结果
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-11-21 DOI: 10.1097/MBP.0000000000000786
Aline Krein Moletta, Cecilia Burigo Corrêa, Silmara S B S Mastroeni, Marco F Mastroeni

Aim: To examine the effect of excess body weight on the blood pressure (BP) of children aged 6-12 years.

Methods: This was a prospective longitudinal study conducted with 187 children at the participants' home in southern Brazil. BP was measured using the auscultatory method. Generalized linear mixed models, including fixed and random effects and adjusted for important covariates, were used to estimate the relative risk (RR) of excess body weight on the incidence of high BP in children throughout the three follow-ups of the study (at ages 6, 9, and 12 years).

Results: The prevalence of high BP increased from 25.0 to 66.7% in children with excess body weight from 6 to 12 years of age. For every 1 kg/m2 increase in the child's BMI, there was an 8% increase (RR = 1.08, 95% confidence interval: 1.00-1.16, P = 0.042) in the risk of the child having high BP from 6 to 12 years of age, even after adjusting for prepregnancy BMI.

Conclusion: Excessive BMI in children increased the risk of high BP in Brazilian children from 6 to 12 years of age. Special attention must be paid to children under 12 years of age with excess body weight to mitigate the onset of cardiovascular diseases throughout life.

目的:探讨超重对6 ~ 12岁儿童血压的影响。方法:这是一项前瞻性纵向研究,在巴西南部的参与者家中进行了187名儿童。采用听诊法测血压。采用广义线性混合模型,包括固定效应和随机效应,并对重要协变量进行调整,以估计在研究的三个随访期间(6岁、9岁和12岁),超重对儿童高血压发病率的相对风险(RR)。结果:超重儿童6 ~ 12岁高血压患病率由25.0%上升至66.7%。儿童BMI每增加1 kg/m2,即使在调整孕前BMI后,6 - 12岁儿童血压升高的风险也会增加8% (RR = 1.08, 95%可信区间:1.00-1.16,P = 0.042)。结论:儿童BMI过高会增加6 - 12岁巴西儿童高血压的风险。必须特别注意体重过重的12岁以下儿童,以减轻一生中心血管疾病的发病。
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引用次数: 0
Validation of B.Well PRO-33 oscillometric blood pressure monitor for professional office use in the general population in accordance with Amendment 2 of the Standard 81060-2:2018 by the International Organization for Standardization (ISO 81060-2:2018/AMD 2:2024). 根据国际标准化组织(ISO 81060-2:2018/AMD 2:2024)标准81060-2:2018修正案2,验证b.w well PRO-33振荡血压监测仪在普通人群中的专业办公用途。
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-11-13 DOI: 10.1097/MBP.0000000000000785
Olga Posnenkova, Margarita Simonyan, Nataliya Akimova

We aimed to evaluate the accuracy of B.Well PRO-33 (B.Well, Widnau, Switzerland) oscillometric device for professional office measurement of blood pressure (BP) on the upper arm in the general population in accordance with the Amendment 2.2024-01 of the Standard 81060-2:2018 by the International Organization for Standardization (ISO 81060-2:2018/AMD 2:2024). Study participants were recruited according to the age, gender, BP, and cuff distribution requirements of the ISO 81060-2:2018/AMD 2:2024 in the general population using the sequential BP measurement method on the same arm. The test device was used with one universal cuff for arm circumferences of 22-42 cm. We chose aneroid sphygmomanometers Riester Big Ben Square Desk (Rudolf Riester, Jungingen, Germany) with small, medium and large cuffs and Welch Allyn 767 Desk (Welch Allyn, Skaneateles Falls, NY, USA) with a large adult cuff for arm circumferences of 22-37 and 38-42 cm, respectively, as control devices. We enrolled 112 study subjects, of whom 85 were analyzed. For validation criterion 1, the mean ± SD of the differences between the readings of the tested device and reference BP (systolic/diastolic; threshold ≤5 ± 8 mmHg; N = 255) was 1.7 ± 5.4/1.8 ± 5.7 mmHg. For validation criterion 2, the SD of the mean BP difference between the tested device and reference BP readings per subject (systolic/diastolic; threshold ≤ 6.73/6.71 mmHg; N = 85) was 4.7/4.7 mmHg. B.Well PRO-33 professional office BP monitor met the requirements of the ISO 81060-2:2018/AMD 2:2024 for the general population, and therefore can be recommended for clinical use.

我们的目的是根据国际标准化组织(ISO 81060-2:2018/AMD 2:24 24)标准81060-2:2018的2.2024-01修正案,评估B.Well PRO-33 (B.Well, Widnau, Switzerland)用于专业办公室测量普通人群上臂血压(BP)的摆动装置的准确性。研究参与者按照ISO 81060-2:2018/AMD 2:24标准的年龄、性别、血压和袖带分布要求在普通人群中招募,使用同一手臂的顺序血压测量方法。测试装置与一个通用袖带一起使用,臂围为22-42厘米。我们选择了无血压计Riester Big Ben Square Desk (Rudolf Riester, juningen, Germany)和Welch Allyn 767 Desk (Welch Allyn, Skaneateles Falls, NY, USA)作为控制装置,分别带有一个大的成人袖带,臂围分别为22-37和38-42厘米。我们招募了112名研究对象,其中85人进行了分析。对于验证标准1,被测装置读数与参考血压(收缩压/舒张压;阈值≤5±8 mmHg; N = 255)之间差异的平均值±SD为1.7±5.4/1.8±5.7 mmHg。对于验证标准2,每个受试者(收缩压/舒张压;阈值≤6.73/6.71 mmHg; N = 85)的被测装置与参考血压读数之间的平均血压差的标准差为4.7/4.7 mmHg。well PRO-33专业办公室血压监测仪符合ISO 81060-2:2018/AMD 2:24对普通人群的要求,因此可以推荐临床使用。
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引用次数: 0
Improving cardiovascular autonomic function in postmenopausal women with hypertension: a pilot study of supervised versus home-based aerobic exercise. 改善绝经后高血压妇女的心血管自主功能:一项监督与家庭有氧运动的初步研究
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-11-11 DOI: 10.1097/MBP.0000000000000782
Cengizhan Gungor, Ezgi Akyildiz Tezcan, Önder Murat Özerbil, Abdullah Tuncez

Objective: Arterial hypertension is a major global cause of cardiovascular disease, a risk heightened by postmenopausal physiological changes. Although aerobic exercise is protective, its optimal intensity, duration, and supervision for hypertensive postmenopausal women remain unclear. This study, therefore, compares a supervised intensive aerobic program with a home-based regimen, assessing their effects on key cardiac health indicators in this population.

Methods: In this single-center pilot randomized controlled trial, we enrolled 31 postmenopausal women. Participants were divided into two groups: one underwent a 6-week supervised intensive aerobic exercise program, and the other followed a home-based exercise regimen. Key outcome measures included cardiorespiratory endurance, heart rate variability, and blood pressure variability. Outcome measures were evaluated at weeks 6 and 12. Intra-group and inter-group comparisons were evaluated using appropriate statistical methods.

Results: After 12 weeks, the supervised exercise group showed significant improvements in VO2max (P = 0.003), metabolic equivalents (METs) (P = 0.002), and standard deviation of normal-to-normal intervals (SDNN) values (P = 0.034) at both the 6th and 12th weeks. However, the sole significant inter-group difference was a greater reduction in 24-hour SBP variability (SBP-SD) in the supervised arm (Δ -0.95 ± 1.15 vs. + 1.54 ± 0.94 mmHg; P = 0.041), driven mainly by the week 6-12 interval (P = 0.004).

Conclusion: Supervised intensive aerobic exercise produced clear within-group gains in VO₂ max, METs, and SDNN, and it reduced 24-hour SBP variability relative to home-based walking. Although between-group differences for the primary fitness and autonomic outcomes were not statistically significant in this pilot, the pattern suggests that a supervised, tailored program may confer additional clinical benefit and merits evaluation in a larger trial.

目的:动脉高血压是全球心血管疾病的主要原因,绝经后的生理变化增加了风险。尽管有氧运动具有保护作用,但其最佳强度、持续时间和对绝经后高血压妇女的监督仍不清楚。因此,本研究比较了有监督的高强度有氧运动和基于家庭的方案,评估了它们对该人群关键心脏健康指标的影响。方法:在这项单中心先导随机对照试验中,我们招募了31名绝经后妇女。参与者被分为两组:一组进行为期6周的有监督的高强度有氧运动计划,另一组则进行基于家庭的锻炼方案。主要结局指标包括心肺耐力、心率变异性和血压变异性。结果测量在第6周和第12周进行评估。采用适当的统计学方法对组内和组间比较进行评价。结果:12周后,监督运动组在第6周和第12周的VO2max (P = 0.003)、代谢当量(METs) (P = 0.002)和正常-正常间隔(SDNN)值的标准差(P = 0.034)方面均有显著改善。然而,唯一显著的组间差异是监督组24小时收缩压变异性(SBP- sd)的更大降低(Δ -0.95±1.15 vs + 1.54±0.94 mmHg; P = 0.041),主要是由第6-12周的间隔(P = 0.004)驱动的。结论:有监督的高强度有氧运动在组内明显增加了vo2max、METs和SDNN,并且相对于在家行走,它降低了24小时收缩压变异性。虽然在本试验中,组间主要适应度和自主神经结果的差异没有统计学意义,但该模式表明,在更大的试验中,有监督的、量身定制的方案可能会带来额外的临床益处和价值评估。
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引用次数: 0
Validation of the CONTEC08C oscillometric blood pressure monitor in adults according to the International Organization for Standardization 81060-2:2018 standard. 根据国际标准化组织81060-2:2018标准验证成人CONTEC08C振荡血压监测仪。
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-11-03 DOI: 10.1097/MBP.0000000000000781
Mengjia Chen, Wenjie Wang, Lu Wang, Jin Bian, Wenjun Ma, Jingjing Bai, Ying Lou, Jun Cai

This study aimed to assess the accuracy of the CONTEC08C automated oscillometric upper-arm sphygmomanometer in adults for clinical use in accordance with the ISO 81060-2:2018 standard. A total of 90 normotensive and hypertensive participants aged 18-75 years were recruited, and 85 were analyzed to evaluate the accuracy of the CONTEC08C oscillometric upper-arm sphygmomanometer using the same arm sequential validation method and a standardized protocol. The mean ± standard deviation (SD) of the differences between the test device and reference blood pressure (BP) measurements was 0.5 ± 3 mmHg for SBP and 0.4 ± 3.5 mmHg for DBP, meeting validation criterion 1. For validation criterion 2, the SD of the averaged differences between the test device and reference BP measurements per subject was 1.81/2.41 mmHg (systolic/diastolic). The CONTEC08C oscillometric upper-arm blood pressure monitor fulfilled the requirements of the ISO 81060-2:2018 standard in adults in the clinical setting and can therefore be recommended for safe clinical use.

本研究旨在根据ISO 81060-2:2018标准评估成人临床使用的CONTEC08C自动振荡上臂血压计的准确性。共招募了90名年龄在18-75岁之间的正常血压和高血压患者,并对其中85人进行了分析,以使用相同的臂序贯验证方法和标准化方案评估CONTEC08C振荡上臂血压计的准确性。试验装置与参考血压(BP)测量值差异的平均值±标准差(SD)为收缩压0.5±3mmhg,舒张压0.4±3.5 mmHg,符合验证标准1。对于验证标准2,每位受试者的测试装置和参考血压测量值之间的平均差异的SD为1.81/2.41 mmHg(收缩压/舒张压)。CONTEC08C振荡上臂血压监测仪在临床环境中满足成人ISO 81060-2:2018标准的要求,因此可以推荐用于安全的临床使用。
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引用次数: 0
Validating the accuracy of Omron HBP-1320 electronic blood pressure monitor in pediatric and adult populations according to Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (ISO 81060-2:2018/Amd 1:2020). 根据医疗器械进步协会/欧洲高血压学会/国际标准化组织(ISO 81060-2:2018/Amd 1:2020),验证欧姆龙HBP-1320电子血压计在儿科和成人人群中的准确性。
IF 1.2 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-10-09 DOI: 10.1097/MBP.0000000000000774
Li Qin, Jie Dong, Hong Jiang, Ya Sun, Jiayi Zhai, Yaya Xue, Ming Liu, Fulai Shen, Yicheng Qiu, Jianhui Xie, Wuquan Huang

Objective: This study aims to evaluate the accuracy of the Omron HBP-1320 electronic blood pressure (BP) monitor for ambulatory BP measurement in both pediatric and adult populations according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) (ISO 81060-2:2018/Amd 1:2020) protocol.

Methods: Subjects who met age, gender, BP, and cuff distribution criteria specified by the AAMI/ESH/ISO (ISO 81060-2:2018/Amd1:2020) protocol were recruited for this study. BP measurements were performed using the same-arm sequential measurement method. The test device was equipped with cuffs suitable for arm circumferences ranging from 12.0 to 42.0 cm.

Results: A total of 87 participants were initially recruited, with 85 (35 children and 50 adults) included in the final analysis after excluding two participants. The mean age of all participants was 38.1 ± 28.98 years, with children averaging 6.7 ± 2.23 years and adults 60.1 ± 15.39 years. For validation criterion 1, the mean ± SD of differences between the test device and reference BP measurements was 2.3 ± 5.47 mmHg for SBP and 1.3 ± 5.65 mmHg for DBP. Both mean differences were ≤5 mmHg, and SDs ≤ 8 mmHg, meeting the criterion. For validation criterion 2, the mean differences were 2.3 ± 3.93 mmHg for SBP and 1.3 ± 5.13 mmHg for DBP, satisfying the thresholds of ≤6.55 mmHg for SBP and ≤6.82 mmHg for DBP.

Conclusion: The Omron HBP-1320 electronic BP monitor meets the requirements of the AAMI/ESH/ISO (ISO 81060-2:2018/Amd 1:2020) validation standard for adults and children.

目的:本研究旨在根据美国医疗器械进步协会/欧洲高血压学会/国际标准化组织(AAMI/ESH/ISO) (ISO 81060-2:2018/Amd 1:2020)协议,评估欧姆龙HBP-1320电子血压监测仪用于儿科和成人动态血压测量的准确性。方法:本研究招募符合AAMI/ESH/ISO (ISO 81060-2:2018/ amdl:2020)协议规定的年龄、性别、血压和袖带分布标准的受试者。血压测量采用同臂顺序测量法。测试装置配备了适合手臂周长12.0至42.0 cm的袖口。结果:最初共招募了87名参与者,在排除两名参与者后,最终分析了85名参与者(35名儿童和50名成人)。所有参与者的平均年龄为38.1±28.98岁,其中儿童平均6.7±2.23岁,成人平均60.1±15.39岁。对于验证标准1,测试装置与参考血压测量值之间的平均±SD差异为收缩压2.3±5.47 mmHg,舒张压1.3±5.65 mmHg。两者的平均差异≤5 mmHg, SDs≤8 mmHg,均符合标准。验证标准2的平均差异为收缩压2.3±3.93 mmHg,舒张压1.3±5.13 mmHg,满足收缩压≤6.55 mmHg和舒张压≤6.82 mmHg的阈值。结论:欧姆龙HBP-1320电子血压监测仪符合成人和儿童AAMI/ESH/ISO (ISO 81060-2:2018/Amd 1:2020)验证标准的要求。
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引用次数: 0
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Blood Pressure Monitoring
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