首页 > 最新文献

British journal of medical & surgical urology最新文献

英文 中文
Management and Outcome of Testicular Torsion in Children: A Teaching Hospital Experience 儿童睾丸扭转的处理和结果:一种教学医院的经验
Pub Date : 2021-01-01 DOI: 10.35248/2168-9857.21.10.146
C. Emeka
Background: Testicular torsion is a common cause of acute scrotum and may lead to ischemia of the testis. The aim of this study was to evaluate our experience in the management of children who had testicular torsion. Materials and Methods: This was a retrospective study of children aged 15 years and younger who were managed for testicular torsion between January 2014 and December 2018 at the pediatric surgery unit of Enugu State University Teaching Hospital Enugu, Nigeria. Results: A total of 79 cases of confirmed testicular torsions were treated during the study period. The median age of the patients was 9 years with a range of 2 weeks to 14 years. Majority of the patients presented 48 hours after onset of their symptoms. The patients received treatment within 24 hours of presentation and abdominal pain was a consistent symptom in all the patients. Half of the patients had a preoperative Doppler ultrasound. Right side of the testis was mostly involved and three-quarters of the patients had orchidopexy whereas one-quarter of the patients had orchidectomy. Surgical site infection was the most common post-operative complication. However, there was no mortality. Conclusion: Delays in presentation may have resulted in testicular loss in 25% of the patients in the present study. We recommend high index of suspicion in children who present with scrotal pain.
背景:睾丸扭转是急性阴囊的常见病因,可导致睾丸缺血。本研究的目的是评估我们在治疗儿童睾丸扭转方面的经验。材料和方法:这是一项回顾性研究,针对2014年1月至2018年12月在尼日利亚埃努古州立大学教学医院埃努古儿科外科治疗睾丸扭转的15岁及以下儿童。结果:本组共收治确诊睾丸扭转79例。患者的中位年龄为9岁,年龄范围为2周到14岁。大多数患者在出现症状48小时后出现。患者在发病24小时内接受治疗,腹痛是所有患者的一致症状。半数患者术前做了多普勒超声检查。睾丸右侧大部分受累,四分之三的患者做了睾丸切除术而四分之一的患者做了睾丸切除术。手术部位感染是最常见的术后并发症。然而,没有死亡率。结论:在本研究中,延迟就诊可能导致25%的患者睾丸丢失。我们建议对患有阴囊疼痛的儿童进行高度怀疑。
{"title":"Management and Outcome of Testicular Torsion in Children: A Teaching Hospital Experience","authors":"C. Emeka","doi":"10.35248/2168-9857.21.10.146","DOIUrl":"https://doi.org/10.35248/2168-9857.21.10.146","url":null,"abstract":"Background: Testicular torsion is a common cause of acute scrotum and may lead to ischemia of the testis. The aim of this study was to evaluate our experience in the management of children who had testicular torsion. Materials and Methods: This was a retrospective study of children aged 15 years and younger who were managed for testicular torsion between January 2014 and December 2018 at the pediatric surgery unit of Enugu State University Teaching Hospital Enugu, Nigeria. Results: A total of 79 cases of confirmed testicular torsions were treated during the study period. The median age of the patients was 9 years with a range of 2 weeks to 14 years. Majority of the patients presented 48 hours after onset of their symptoms. The patients received treatment within 24 hours of presentation and abdominal pain was a consistent symptom in all the patients. Half of the patients had a preoperative Doppler ultrasound. Right side of the testis was mostly involved and three-quarters of the patients had orchidopexy whereas one-quarter of the patients had orchidectomy. Surgical site infection was the most common post-operative complication. However, there was no mortality. Conclusion: Delays in presentation may have resulted in testicular loss in 25% of the patients in the present study. We recommend high index of suspicion in children who present with scrotal pain.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"150 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81064648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Introduction to Pelvic Surgery 骨盆外科导论
Pub Date : 2021-01-01 DOI: 10.35248/2168-9857.21.10.E126
Paraskev Katsakori
{"title":"An Introduction to Pelvic Surgery","authors":"Paraskev Katsakori","doi":"10.35248/2168-9857.21.10.E126","DOIUrl":"https://doi.org/10.35248/2168-9857.21.10.E126","url":null,"abstract":"","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"23 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72759520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Overview on Erectile Dysfunction and Prevention 勃起功能障碍及其预防综述
Pub Date : 2021-01-01 DOI: 10.35248/2168-9857.21.10.265
Caiga Du
{"title":"An Overview on Erectile Dysfunction and Prevention","authors":"Caiga Du","doi":"10.35248/2168-9857.21.10.265","DOIUrl":"https://doi.org/10.35248/2168-9857.21.10.265","url":null,"abstract":"","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"10 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78592095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experiences of Adults with Congenital Bowel and Bladder Conditions 成人先天性肠道和膀胱疾病的经验
Pub Date : 2021-01-01 DOI: 10.35248/2168-9857.21.10.253
Paraskev Katsakori
{"title":"Experiences of Adults with Congenital Bowel and Bladder Conditions","authors":"Paraskev Katsakori","doi":"10.35248/2168-9857.21.10.253","DOIUrl":"https://doi.org/10.35248/2168-9857.21.10.253","url":null,"abstract":"","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"26 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82792574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hematuria after Transrectal Prostate Biopsy: A Warning of Future Infection 经直肠前列腺活检后血尿:未来感染的警告
Pub Date : 2020-01-01 DOI: 10.35248/2168-9857.20.9.233
A. Quach, C. O’Donnell, M. Al-Musawi, Simon P. Kim, T. Macdermott, A. Barqawi
Purpose: To identify the incidence and predictive factors of infectious complications in a prophylactic-controlled cohort of men undergoing transrectal ultrasound-guided prostate needle biopsy (TRUS-Bx) at a single institution. Materials and Methods: A retrospective review was performed on 539 patients who underwent TRUS-Bx between 2010-2015. All patients received prophylactic Sulfamethoxazole/Trimethoprim and Levofloxacin prior to the biopsy. Charlson Comorbidity Index (CCI) was calculated for each patient. The characteristics of patients with and without infectious complications were compared using Fisher exact tests and student’s t-test. Results: 539 biopsies were performed. Mean age was 64 years, PSA was 17, prostate volume was 41 mL, and CCI score was 3. A total of 7 (1.3%) infectious complications were reported 48-72 hours after biopsy, with 2 (0.4%) developing sepsis. Analysis indicated no significant differences in mean age (p=0.544), PSA (p=0.881), prostate volume (p=0.532), or CCI score (p=0.499) among patients who developed infection. Individual components of the CCI revealed no statistically significant differences. Additional complications following biopsy included: hematuria (8.3%), rectal bleeding (1.3%), urinary urgency (0.9%), and new onset erectile dysfunction (0.6%). Hematuria was associated with the development of infectious complications (OR=8.75, CI 1.895–40.400, p=0.0055). Conclusions: Our cohort of patients undergoing TRUS-Bx had a lower infectious rate compared to that reported by the AUA (1.1% vs 5-7%). Although this study has limited power, CCI was poorly predictive of infectious complications following TRUS-Bx. Persistent hematuria following biopsy was associated with infectious complications. The clinical importance of hematuria following TRUS-Bx, if any, needs to be further clarified.
目的:确定在单一机构接受经直肠超声引导前列腺穿刺活检(truss - bx)的男性预防对照队列中感染并发症的发生率和预测因素。材料与方法:对2010-2015年间539例接受TRUS-Bx治疗的患者进行回顾性分析。所有患者在活检前均接受预防性磺胺甲恶唑/甲氧苄啶和左氧氟沙星治疗。计算每位患者的Charlson共病指数(CCI)。采用Fisher精确检验和学生t检验比较有无感染性并发症患者的特征。结果:共行活组织检查539例。平均年龄64岁,PSA 17,前列腺体积41 mL, CCI评分3分。活检后48-72小时共报告了7例(1.3%)感染并发症,其中2例(0.4%)发生败血症。分析显示,发生感染的患者在平均年龄(p=0.544)、PSA (p=0.881)、前列腺体积(p=0.532)或CCI评分(p=0.499)方面无显著差异。CCI的各个组成部分没有显示出统计学上的显著差异。活检后的其他并发症包括:血尿(8.3%)、直肠出血(1.3%)、尿急(0.9%)和新发勃起功能障碍(0.6%)。血尿与感染并发症的发生相关(OR=8.75, CI 1.895-40.400, p=0.0055)。结论:与AUA报道的感染率相比,我们的队列患者接受TRUS-Bx的感染率较低(1.1%对5-7%)。虽然这项研究的效力有限,但CCI对TRUS-Bx术后感染并发症的预测效果很差。活检后持续血尿与感染并发症相关。如果有血尿的临床重要性,则需要进一步澄清。
{"title":"Hematuria after Transrectal Prostate Biopsy: A Warning of Future Infection","authors":"A. Quach, C. O’Donnell, M. Al-Musawi, Simon P. Kim, T. Macdermott, A. Barqawi","doi":"10.35248/2168-9857.20.9.233","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.233","url":null,"abstract":"Purpose: To identify the incidence and predictive factors of infectious complications in a prophylactic-controlled cohort of men undergoing transrectal ultrasound-guided prostate needle biopsy (TRUS-Bx) at a single institution. Materials and Methods: A retrospective review was performed on 539 patients who underwent TRUS-Bx between 2010-2015. All patients received prophylactic Sulfamethoxazole/Trimethoprim and Levofloxacin prior to the biopsy. Charlson Comorbidity Index (CCI) was calculated for each patient. The characteristics of patients with and without infectious complications were compared using Fisher exact tests and student’s t-test. Results: 539 biopsies were performed. Mean age was 64 years, PSA was 17, prostate volume was 41 mL, and CCI score was 3. A total of 7 (1.3%) infectious complications were reported 48-72 hours after biopsy, with 2 (0.4%) developing sepsis. Analysis indicated no significant differences in mean age (p=0.544), PSA (p=0.881), prostate volume (p=0.532), or CCI score (p=0.499) among patients who developed infection. Individual components of the CCI revealed no statistically significant differences. Additional complications following biopsy included: hematuria (8.3%), rectal bleeding (1.3%), urinary urgency (0.9%), and new onset erectile dysfunction (0.6%). Hematuria was associated with the development of infectious complications (OR=8.75, CI 1.895–40.400, p=0.0055). Conclusions: Our cohort of patients undergoing TRUS-Bx had a lower infectious rate compared to that reported by the AUA (1.1% vs 5-7%). Although this study has limited power, CCI was poorly predictive of infectious complications following TRUS-Bx. Persistent hematuria following biopsy was associated with infectious complications. The clinical importance of hematuria following TRUS-Bx, if any, needs to be further clarified.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"37 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81544392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posthectomy Approach of Erythroplasia of Queyrat: A Case-Report 魁地鼠红细胞增生手术后入路1例报告
Pub Date : 2020-01-01 DOI: 10.35248/2168-9857.20.9.227
A. Traoré, Ibrahima Diallo, O. Sow, M. Dione, N. Ndour, Modou Ndiaye, A. Ndiath, B. Fall
Erythroplasia of Queyrat stands for a precancerous lesion, a carcinoma in situ evolving through an epidermoid carcinoma in the absence of an appropriate management. We report a case of 66-year-old uncircumcised Caucasian patient who was suffering from a lesion of erythroplasia of Queyrat located at the penis and treated by posthectomy after failure of a cream-based chemotherapy. The diagnosis of Erythroplasia of Queyrat is histological. In our patient, the race and the absence of circumcision allowed us to conjure up the diagnosis. Surgical treatment seems to be the refferential approach in the management of this intra-epithelial neoplasia.
Queyrat红细胞增生症代表癌前病变,在缺乏适当治疗的情况下,原位癌演变为表皮样癌。我们报告一个66岁的未割包皮的白人患者,他患有位于阴茎的奎拉红细胞增生病变,在乳霜化疗失败后接受手术切除治疗。奎拉红细胞增生症的诊断是组织学上的。在我们的病人身上,种族和没有包皮环切术使我们能够想象出诊断结果。手术治疗似乎是管理这种上皮内瘤变的参考方法。
{"title":"Posthectomy Approach of Erythroplasia of Queyrat: A Case-Report","authors":"A. Traoré, Ibrahima Diallo, O. Sow, M. Dione, N. Ndour, Modou Ndiaye, A. Ndiath, B. Fall","doi":"10.35248/2168-9857.20.9.227","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.227","url":null,"abstract":"Erythroplasia of Queyrat stands for a precancerous lesion, a carcinoma in situ evolving through an epidermoid carcinoma in the absence of an appropriate management. We report a case of 66-year-old uncircumcised Caucasian patient who was suffering from a lesion of erythroplasia of Queyrat located at the penis and treated by posthectomy after failure of a cream-based chemotherapy. The diagnosis of Erythroplasia of Queyrat is histological. In our patient, the race and the absence of circumcision allowed us to conjure up the diagnosis. Surgical treatment seems to be the refferential approach in the management of this intra-epithelial neoplasia.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"18 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81947487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complete Rupture of the Urethra Associated With a Fracture of the Two Corpora Cavernosa: About Two Cases 尿道完全破裂合并双海绵体骨折2例
Pub Date : 2020-01-01 DOI: 10.24105/2168-9857.9.231
O. Gaye, A. Traoré, S. Faye, H. Diallo, N. M. Thiam, N. Ndour, M. Diaw, M. Ndiaye, A. Ndiath, O. Sow, B. Sine, A. Sarr, A. Thiam, C. Z. Ondo, R. Kane, A. Ndiaye, B. Fall, B. Diao, A. Ndoye
We report two cases of fracture of the two cavernous bodies associated with a complete rupture of the secondary urethra to a false step of coitus. This association is exceptional. Emergency surgical exploration makes it possible to make a precise lesion assessment and to repair them to obtain better functional results.
我们报告两例骨折的两个海绵体与第二尿道完全破裂相关联的假步骤性交。这种联系是特殊的。急诊探查可以对病变进行精确的评估和修复,以获得更好的功能效果。
{"title":"Complete Rupture of the Urethra Associated With a Fracture of the Two Corpora Cavernosa: About Two Cases","authors":"O. Gaye, A. Traoré, S. Faye, H. Diallo, N. M. Thiam, N. Ndour, M. Diaw, M. Ndiaye, A. Ndiath, O. Sow, B. Sine, A. Sarr, A. Thiam, C. Z. Ondo, R. Kane, A. Ndiaye, B. Fall, B. Diao, A. Ndoye","doi":"10.24105/2168-9857.9.231","DOIUrl":"https://doi.org/10.24105/2168-9857.9.231","url":null,"abstract":"We report two cases of fracture of the two cavernous bodies associated with a complete rupture of the secondary urethra to a false step of coitus. This association is exceptional. Emergency surgical exploration makes it possible to make a precise lesion assessment and to repair them to obtain better functional results.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"193 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78505992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meatal Stenosis Post Traditional Neonatal Circumcision-Cross Sectional Study 传统新生儿包皮环切术后食管狭窄的横断面研究
Pub Date : 2020-01-01 DOI: 10.35248/2168-9857.20.9.234
A. Abid
Context: Circumcision holds a unique place in daily practice of urology. Heat cautery device is most common local technique used we found it can cause meatal stenosis and its sequels. Aim: To determine the incidence, presenting symptoms of meatal stenosis and its relation to local traditional neonatal circumcision techniques among our children. Settings and Design: This retrospectively study. Methods and Materials: Total 150 child who circumcised during infancy period, outside medical institutes and they circumcised using local traditional techniques either heating cautery device or surgical knives. Statistical analysis of data was carried out using the Statistical Packages for Social Sciences- version 25 (IBM Corporation). Results: Of 150 child, 60 (40%) had meatal stenosis. The mean age at time of diagnosis was 5.98 ± 3.06 years (Range 1-13 years) and the majority of patients was within age group of 5-9 years (n.31, 51.7%), median 6.0 years. The incidence of MS was significantly higher (P=0.037) among group of child circumcised with heating device in comparison with circumcised group with other method. Forty-six child (76.7%) were symptomatic and fourteen child (23.3%) diagnosis of MS had made incidentally. Conclusions: Meatal stenosis is a long-term complication of neonatal circumcision with a late presentation and sequels. It is more commonly among group circumcised using heating cautery. We recommend using heating cautery cautiously.
背景:包皮环切术在泌尿科的日常实践中占有独特的地位。热烧灼装置是最常用的局部技术,我们发现它可以引起金属狭窄及其后遗症。目的:了解小儿金属狭窄的发生率、表现及与当地传统新生儿包皮环切术的关系。背景和设计:回顾性研究。方法与材料:150例婴幼儿期在医疗机构外行包皮环切术的患儿,采用当地传统的加热烧灼器或手术刀包皮环切术。使用社会科学统计软件包-第25版(IBM公司)对数据进行统计分析。结果:150例患儿中,60例(40%)发生牙髓狭窄。平均诊断年龄5.98±3.06岁(1 ~ 13岁),5 ~ 9岁年龄组占多数(31例,51.7%),中位年龄6.0岁。加热装置包皮环切组MS发生率明显高于其他方式包皮环切组(P=0.037)。有症状者46例(76.7%),附带诊断者14例(23.3%)。结论:新生儿包皮环切术后,金属瓣狭窄是一种长期并发症,表现较晚,后遗症较重。在使用加热烧灼法进行包皮环切术的人群中更为常见。我们建议谨慎使用电热器具。
{"title":"Meatal Stenosis Post Traditional Neonatal Circumcision-Cross Sectional Study","authors":"A. Abid","doi":"10.35248/2168-9857.20.9.234","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.234","url":null,"abstract":"Context: Circumcision holds a unique place in daily practice of urology. Heat cautery device is most common local technique used we found it can cause meatal stenosis and its sequels. Aim: To determine the incidence, presenting symptoms of meatal stenosis and its relation to local traditional neonatal circumcision techniques among our children. Settings and Design: This retrospectively study. Methods and Materials: Total 150 child who circumcised during infancy period, outside medical institutes and they circumcised using local traditional techniques either heating cautery device or surgical knives. Statistical analysis of data was carried out using the Statistical Packages for Social Sciences- version 25 (IBM Corporation). Results: Of 150 child, 60 (40%) had meatal stenosis. The mean age at time of diagnosis was 5.98 ± 3.06 years (Range 1-13 years) and the majority of patients was within age group of 5-9 years (n.31, 51.7%), median 6.0 years. The incidence of MS was significantly higher (P=0.037) among group of child circumcised with heating device in comparison with circumcised group with other method. Forty-six child (76.7%) were symptomatic and fourteen child (23.3%) diagnosis of MS had made incidentally. Conclusions: Meatal stenosis is a long-term complication of neonatal circumcision with a late presentation and sequels. It is more commonly among group circumcised using heating cautery. We recommend using heating cautery cautiously.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"19 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83388322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Randomized, Open label, Comparative Clinical Study to Evaluate the Efficacy and Safety of Cystone Forte Tablet in Urolithiasis 一项随机、开放标签、比较临床研究:评价复方膀胱石片治疗尿石症的疗效和安全性
Pub Date : 2020-01-01 DOI: 10.35248/2168-9857.20.9.235
Rajeev Chaudhari, P. Shah, Archana Shetty
The aim of the study was to evaluate the efficacy and safety of Cystone forte tablet in urolithiasis. A randomized, open-label, comparative clinical study was conducted in sixty-two subjects presenting with urolithiasis as diagnosed clinically with calculi measuring 5 to 12mm in size and subjects aged between 18-50 years of either sex. Sixty-two subjects were randomized into trial group and comparator group. Trial group subjects received Cystone forte tablet in the dose of 2 tablets twice daily for a period of 6 weeks while the comparator group received Tamsulosin tablet in the dose of 1 tablet once daily for a period of 6 weeks. The trial group subjects treated with Cystone forte tablets showed comparable results with the improvement of clinical parameters in urolithiasis and with the expulsion of kidney stones as compared to Tamsulosin group. The trial group receiving Cystone forte tablet was found to be effective and was beneficial in the management of urolithiasis. At the end of the study, mild occasional adverse events were reported in both the groups which were resolved. This clinical study demonstrates that, oral administration of Cystone forte tablets at the recommended dose is safe and effective in relieving the symptoms of urolithiasis.
本研究的目的是评价盐酸赛石酮片治疗尿石症的疗效和安全性。一项随机、开放标签、比较临床研究对62名临床诊断为尿石症且结石尺寸为5 - 12mm的患者进行了研究,受试者年龄在18-50岁之间,男女不限。将62例受试者随机分为试验组和比较组。试验组患者给予盐酸赛通片,剂量为2片,每日2次,连续6周;对照组患者给予坦索罗辛片,剂量为1片,每日1次,连续6周。与坦索罗辛组相比,试验组接受强赛石片治疗的受试者在尿石症的临床参数改善和肾结石排出方面显示出相当的结果。试验组服用复方赛石片治疗尿石症疗效显著。在研究结束时,两组都报告了轻微的偶尔不良事件,这些事件都得到了解决。本临床研究表明,按推荐剂量口服强赛石片对缓解尿石症症状是安全有效的。
{"title":"A Randomized, Open label, Comparative Clinical Study to Evaluate the Efficacy and Safety of Cystone Forte Tablet in Urolithiasis","authors":"Rajeev Chaudhari, P. Shah, Archana Shetty","doi":"10.35248/2168-9857.20.9.235","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.235","url":null,"abstract":"The aim of the study was to evaluate the efficacy and safety of Cystone forte tablet in urolithiasis. A randomized, open-label, comparative clinical study was conducted in sixty-two subjects presenting with urolithiasis as diagnosed clinically with calculi measuring 5 to 12mm in size and subjects aged between 18-50 years of either sex. Sixty-two subjects were randomized into trial group and comparator group. Trial group subjects received Cystone forte tablet in the dose of 2 tablets twice daily for a period of 6 weeks while the comparator group received Tamsulosin tablet in the dose of 1 tablet once daily for a period of 6 weeks. The trial group subjects treated with Cystone forte tablets showed comparable results with the improvement of clinical parameters in urolithiasis and with the expulsion of kidney stones as compared to Tamsulosin group. The trial group receiving Cystone forte tablet was found to be effective and was beneficial in the management of urolithiasis. At the end of the study, mild occasional adverse events were reported in both the groups which were resolved. This clinical study demonstrates that, oral administration of Cystone forte tablets at the recommended dose is safe and effective in relieving the symptoms of urolithiasis.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"11 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72799439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathology of the Peritoneal-Vaginal Canal in Children in Rural Areas 农村儿童腹膜-阴道管病理
Pub Date : 2020-01-01 DOI: 10.35248/2168-9857.20.9.229
Mieret Jean Claude, L. Vincent, M. Michel, Dieth Atafi
The purpose of this study was to identify the closure anomalies of the peritoneal-vaginal canal in order to describe the epidemiological, anatomo-clinical and therapeutic aspects in our practice. Patients and methods: As part of the community health program, we conducted a descriptive cross-sectional study in the Cuvette Ouest department, Oyo city Congo. It took place from May 25th to July 25th, 2017 (2 months). Included in the study were male children, admitted for inguinal, inguino-scrotal or scrotal swelling and for whom the surgical procedure made it possible to note a form of persistence of the peritoneal-vaginal canal. For each cases, epidemiological, anatomo-clinical and therapeutic aspects were analyzed. Results: A total of 277 patients were treated over a period of 2 months. The average age was 6.5 years (1 month-17 years). The reason for consultation was inguinal and inguino-scrotal swelling, painless and intermittent in 57%. Pathology of the peritoneo-vaginal canal was located on the right side in 142 cases. The anatomo-clinical types were dominated by hernia in 57%. Pathology of the peritoneo-vaginal canal was associated with umbilical hernia in 44% and prosthectomy was done in 16.6%. The treatment was surgical in all our patients. The operative course was marked by two cases of scrotal hematoma and five cases of parietal suppuration. Conclusion: The pathologies of the peritoneal-vaginal canal are very frequent in children in pediatric surgery departments and are dominated by inguinal and inguino-scrotal hernias. Their treatment is surgical.
本研究的目的是确定腹膜-阴道管闭合异常,以描述我们实践中的流行病学,解剖学-临床和治疗方面。患者和方法:作为社区卫生计划的一部分,我们在刚果Oyo市Cuvette west部门进行了一项描述性横断面研究。会议于2017年5月25日至7月25日(2个月)举行。该研究包括因腹股沟、腹股沟-阴囊或阴囊肿胀而入院的男性儿童,对于他们,手术可以注意到腹膜-阴道管的一种形式的持久性。对每个病例进行流行病学、解剖临床和治疗方面的分析。结果:277例患者在2个月的时间内接受了治疗。平均年龄6.5岁(1个月-17岁)。会诊原因为腹股沟和腹股沟-阴囊肿胀,57%为无痛性和间歇性。142例病理显示腹膜阴道管位于右侧。解剖临床型以疝型为主,占57%。44%的腹膜阴道管病理与脐疝相关,16.6%的患者行假体切除术。我们所有的病人都是手术治疗。手术过程中出现阴囊血肿2例,腹壁化脓5例。结论:小儿外科患儿腹膜-阴道管病变发生率高,以腹股沟疝和腹股沟-阴囊疝为主。他们的治疗是外科手术。
{"title":"Pathology of the Peritoneal-Vaginal Canal in Children in Rural Areas","authors":"Mieret Jean Claude, L. Vincent, M. Michel, Dieth Atafi","doi":"10.35248/2168-9857.20.9.229","DOIUrl":"https://doi.org/10.35248/2168-9857.20.9.229","url":null,"abstract":"The purpose of this study was to identify the closure anomalies of the peritoneal-vaginal canal in order to describe the epidemiological, anatomo-clinical and therapeutic aspects in our practice. Patients and methods: As part of the community health program, we conducted a descriptive cross-sectional study in the Cuvette Ouest department, Oyo city Congo. It took place from May 25th to July 25th, 2017 (2 months). Included in the study were male children, admitted for inguinal, inguino-scrotal or scrotal swelling and for whom the surgical procedure made it possible to note a form of persistence of the peritoneal-vaginal canal. For each cases, epidemiological, anatomo-clinical and therapeutic aspects were analyzed. Results: A total of 277 patients were treated over a period of 2 months. The average age was 6.5 years (1 month-17 years). The reason for consultation was inguinal and inguino-scrotal swelling, painless and intermittent in 57%. Pathology of the peritoneo-vaginal canal was located on the right side in 142 cases. The anatomo-clinical types were dominated by hernia in 57%. Pathology of the peritoneo-vaginal canal was associated with umbilical hernia in 44% and prosthectomy was done in 16.6%. The treatment was surgical in all our patients. The operative course was marked by two cases of scrotal hematoma and five cases of parietal suppuration. Conclusion: The pathologies of the peritoneal-vaginal canal are very frequent in children in pediatric surgery departments and are dominated by inguinal and inguino-scrotal hernias. Their treatment is surgical.","PeriodicalId":89536,"journal":{"name":"British journal of medical & surgical urology","volume":"4 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86367414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
British journal of medical & surgical urology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1