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Evaluation of Exposure Assessment Methods and Procedures for Induction Hobs 感应滚刀的暴露评估方法和程序的评价
IF 1.2 3区 生物学 Q3 BIOLOGY Pub Date : 2025-09-29 DOI: 10.1002/bem.70024
Jingtian Xi, Sven Kühn, Cosimo Fortunato, Erdem Ofli, Niels Kuster
<p>Induction hobs generate strong alternating magnetic fields to heat pots by inducing eddy currents. These fields are the strongest close to the bottom of the cookware, but stray fields at large distances can still be substantial. In general, these are higher than the reference levels defined by international electromagnetic exposure safety guidelines (ICNIRP 1998; ICNIRP 2010; IEEE 2019). That the reference levels are exceeded does not imply that the basic restrictions are also violated. In this study, we assess the exposures caused by the latest generation of induction hobs by applying the advanced instrumentation and different methods that include the procedures developed by the International Electrotechnical Commission (IEC) for household appliances (IEC 62233) (IEC International Electrotechnical Commission 2005), the 4-tier approach developed for inductive wireless power transfer systems (IEC 63184) (IEC International Electrotechnical Commission 2021), and their derivatives. First, methods for determining the maximum exposure configuration were assessed. Then, the 3D distribution of the incident magnetic field was sampled with a scanning system and analyzed, and the contact currents assessed. Lastly, numerical dosimetric evaluations were performed in anatomical models to determine the maximum fields induced by the measured incident fields directly or by a representative coil model converted from the measured fields. The study's findings reveal significant variations in exposure across different induction hobs, with differences of up to a factor of <span></span><math> <semantics> <mrow> <mo>></mo> </mrow> <annotation> $gt $</annotation> </semantics></math> 20 (<span></span><math> <semantics> <mrow> <mo>></mo> </mrow> <annotation> $gt $</annotation> </semantics></math> 26 dB) as a function of power, coil size, and proximity to the coil. This suggests that low-exposure hobs can be designed without compromising cooking performance. Furthermore, the study strengthens the conclusions of previous studies that IEC 62233 (IEC International Electrotechnical Commission 2005) may underestimate the exposure for persons standing next to the hob by up to a factor of <span></span><math> <semantics> <mrow> <mo>></mo> </mrow> <annotation> $gt $</annotation> </semantics></math> 30—based on testing according to the exposure limits from (ICNIRP 1998; IEEE 2019)—and thus does not ensure safety. A dosimetric analysis, the most accurate method, would be relatively costly. Alternative approaches derived from (IEC International Electrotechnical Commission, 2021) that are affordable and not overly conservative are discussed. Bioelectromagnetics. 00:
感应滚刀通过感应涡流产生强大的交变磁场来加热锅。这些磁场在靠近炊具底部的地方最强,但远距离的杂散磁场仍然很大。一般来说,这些高于国际电磁暴露安全指南(ICNIRP 1998; ICNIRP 2010; IEEE 2019)定义的参考水平。超过了参考水平并不意味着也违反了基本限制。在本研究中,我们通过应用先进的仪器和不同的方法来评估最新一代感应滚刀造成的暴露,这些方法包括国际电工委员会(IEC)为家用电器(IEC 62233) (IEC国际电工委员会2005)制定的程序,为感应无线电力传输系统开发的四层方法(IEC 63184) (IEC国际电工委员会2021),以及它们的导数。首先,评估了确定最大暴露配置的方法。然后,利用扫描系统对入射磁场的三维分布进行采样和分析,并评估接触电流。最后,在解剖模型中进行了数值剂量学评估,以确定直接测量的入射场或由测量场转换的代表性线圈模型引起的最大场。该研究的发现揭示了不同的感应滚刀暴露的显著差异,差异高达>; $gt $ 20 (> $gt $ 26 dB),这是功率、线圈尺寸和与线圈的接近程度的函数。这表明,低暴露的炉具可以在不影响烹饪性能的情况下设计。此外,该研究加强了先前研究的结论,即IEC 62233 (IEC国际电工委员会2005年)可能低估了站在滚刀旁边的人的暴露,根据(ICNIRP 1998; IEEE 2019)的暴露限值进行测试,最高可达30倍-因此不能确保安全。剂量学分析是最准确的方法,但成本相对较高。本文讨论了来自(IEC国际电工委员会,2021)的可负担且不过于保守的替代方法。生物电磁学。00:00 - 00,2025。©2025生物电磁学学会。
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引用次数: 0
Dosimetric Electromagnetic Safety of People With Implants: A Neglected Population? 人体植入物的剂量学电磁安全:一个被忽视的人群?
IF 1.2 3区 生物学 Q3 BIOLOGY Pub Date : 2025-09-25 DOI: 10.1002/bem.70023
Lena Kranold, Jingtian Xi, Tolga Goren, Niels Kuster

Electromagnetic (EM) safety guidelines are designed to protect the general public and workers from the risks posed by exposure to EM sources of all types, with the exception of medical EM sources. However, it has never been systematically evaluated whether individuals with conductive implants are also protected by these guidelines or whether the local field enhancement due to presence of the implant may pose an unacceptable risk under certain realistic exposure conditions. To address this important knowledge and regulatory gap, we first evaluated the upper bound of the local enhancement of bare and insulated generic implants of 0.5 λ (approximately equal to resonant) and 0.1 λ lengths, but restricted the maximum length to 2 m, as a function of tissue properties and frequency (10 kHz to 1 GHz). Results for uniform electric field excitation showed local enhancement of psSAR10mg and of locally averaged E-field, respectively, compared to the background in the presence of a generic implant of 10 dB (1 GHz) to over 100 dB at frequencies under 100 MHz. In the next step, we tested the hypothesis that fields induced inside the human body by realistic near-field sources are not sufficiently uniform to generate results in enhancement that could pose unacceptable risk. Common implant trajectories were inserted into the Virtual Population human anatomical model Ella V3.0, and the model was exposed to the following conditions (i) a standard source representing a wireless power transfer source operating at 85 kHz and (ii) a dipole source that operates at 450 MHz within the current exposure limits. Results show that the safety limit is exceeded at the tip of the implant by a factor of > 10 ( > 20 dB) or > 115 V/m at 85 kHz, whereas the locally induced specific absorption rate averaged over 10 mg at 450 MHz was 7.9 W/kg, resulting in a temperature increase after 6 min of < 0.4 K. Hence, as the hypothesis was falsified at frequencies < 450 MHz, patients with implants are inadequately protected by current safety and product guidelines. In the discussions, proposals for how to close this regulatory gap are provided. Bioelectromagnetics. 00:00–00, 2025. © 2025 Bioelectromagnetics Society.

电磁(EM)安全指南旨在保护公众和工作人员免受暴露于所有类型电磁源(医疗电磁源除外)所造成的风险。然而,从未系统地评估过使用导电植入物的个体是否也受到这些指南的保护,或者在某些现实暴露条件下,由于植入物的存在而导致的局部场增强是否会造成不可接受的风险。为了解决这一重要的知识和监管空白,我们首先评估了裸和绝缘通用植入物的局部增强的上界,0.5 λ(大约等于谐振)和0.1 λ长度,但将最大长度限制为2 m,作为组织特性和频率(10 kHz至1 GHz)的函数。均匀电场激励的结果显示,在100mhz频率下,与普通植入物10db (1ghz)到100db以上的背景相比,psSAR10mg和局部平均电场分别有局部增强。在下一步中,我们测试了一个假设,即由现实的近场光源在人体内诱导的场不够均匀,无法产生可能造成不可接受风险的增强结果。将常见的植入物轨迹插入到虚拟种群人体解剖模型Ella V3.0中,并将模型暴露在以下条件下(i)工作频率为85 kHz的无线电源传输源的标准源和(ii)在当前暴露限值内工作频率为450 MHz的偶极子源。结果表明,在85 kHz时,植入物的尖端超过了安全极限>; 10 (> 20 dB)或>; 115 V/m,而在450 MHz时,超过10 mg的局部诱导比吸收率平均为7.9 W/kg,导致0.4 K作用6 min后温度升高。因此,由于该假设在450mhz频率下被证伪,植入物的患者没有得到现行安全和产品指南的充分保护。在讨论中,提出了如何缩小这一监管差距的建议。生物电磁学。00:00 - 00,2025。©2025生物电磁学学会。
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引用次数: 0
Design and Dosimetric Analysis of a Whole-Body Exposure Setup for Investigating Possible Effects of 50 Hz Magnetic Fields on Sleep and Markers of Alzheimer's Disease 研究50hz磁场对睡眠和阿尔茨海默病标志物可能影响的全身暴露装置的设计和剂量学分析
IF 1.2 3区 生物学 Q3 BIOLOGY Pub Date : 2025-09-09 DOI: 10.1002/bem.70022
Gernot Schmid, Pia Schneeweiss, Rene Hirtl, Johannes Kainz, Cornelia Sauter, Heidi Danker-Hopfe, Hans Dorn

A new whole-body exposure facility for a randomized, double-blind, cross-over provocation study investigating possible effects of 50 Hz magnetic field exposure on sleep and markers of Alzheimer's disease has been developed and dosimetrically analyzed. The exposure facility was custom-tailored for the sleep laboratory where the study was carried out and enables magnetic flux densities of up to 30 μT with a maximum field inhomogeneity of less than ± 20%. Exposure is applied fully software-controlled and in a blinded and randomized manner. The orientation of the applied magnetic field vector is varied by the control software to create a uniformly distributed set of field vector orientations throughout each experimental session. A numerical dosimetric analysis of the exposure facility was carried out using several high-resolution anatomical body models. Induced electric field strengths in the range of 0.5–0.6 mV/m (99.9th percentile of 2 × 2 × 2 mm3 averaged induced electric field strength Ei) inside the brain at an external exposure level of 30 μT were obtained for magnetic field vector orientations along the three main axes (front-back, left-right, head-feet). Statistics of volume averaged values of Ei, analyzed for several hundred different brain regions of gray matter, under exposure with varying magnetic field vector orientations yield value ranges of 0.001–0.065 mV/m (minima), 0.025–0.21 mV/m (mean values), and 0.033–0.34 mV/m (maxima). The developed exposure facility was successfully deployed in a recently completed experimental study. Bioelectromagnetics. 00:00–00, 2025. © 2025 © 2025 Bioelectromagnetics Society.

一种新的全身暴露设备用于随机、双盲、交叉激发研究,研究50hz磁场暴露对睡眠和阿尔茨海默病标志物的可能影响,并进行了剂量学分析。暴露设备是为进行研究的睡眠实验室定制的,可实现高达30 μT的磁通密度,最大场不均匀性小于±20%。曝光完全由软件控制,采用盲法和随机方式。应用磁场矢量的方向由控制软件改变,以在每次实验过程中创建一组均匀分布的场矢量方向。使用几个高分辨率解剖体模型对暴露设施进行了数值剂量学分析。在30 μT的外部暴露水平下,沿前-后、左-右、头-脚三个主轴方向的磁场矢量方向,获得了脑内0.5 ~ 0.6 mV/m范围内的感应电场强度(2 × 2 × 2 mm3平均感应电场强度Ei的99.9%)。统计了数百个脑灰质不同区域在不同磁场矢量方向照射下的Ei体积平均值,产生值范围为0.001 ~ 0.065 mV/m(最小值)、0.025 ~ 0.21 mV/m(平均值)和0.033 ~ 0.34 mV/m(最大值)。在最近完成的一项实验研究中成功地部署了开发的暴露设施。生物电磁学。00:00 - 00,2025。©2025©2025生物电磁学学会。
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引用次数: 0
Looking for Biomarkers Which May Explain Idiopathic Environmental Intolerance Attributed to Electromagnetic Fields (IEI-EMF): Does RF-EMF Exposure Influence Salivary Cortisol Response? 寻找可能解释电磁场(IEI-EMF)引起的特发性环境不耐受的生物标志物:RF-EMF暴露是否影响唾液皮质醇反应?
IF 1.2 3区 生物学 Q3 BIOLOGY Pub Date : 2025-09-05 DOI: 10.1002/bem.70021
Adam Verrender, Jacob Manley, Nikkeah K. Wallace, Sarah P. Loughran, Rodney J. Croft

In order to understand Idiopathic Environmental Intolerance attributed to Electromagnetic Fields (IEI-EMF), it has been argued that it is crucial to test for effects of radiofrequency electromagnetic fields (RF-EMF) on biomarkers, given that they can be more objective than symptom reports. While no clear evidence links RF-EMF exposure to biomarker changes, research remains limited and largely speculative due to the lack of known bioeffect mechanisms. However, there is in vitro evidence that cortisol is affected by heating, which, as RF-EMF causes heating, raises the possibility that RF-EMF exposure may increase cortisol via thermally mediated processes. If cortisol is affected by RF-EMF exposure, it may form part of a broader aetiology of IEI-EMF, where RF-EMF-induced physiological (cortisol) inputs first generate somatic sensations, which are then fostered by expectancy or learning-based processes to generate symptoms. However, studies investigating whether RF-EMF exposure influences cortisol have reported inconsistent, but mostly null results, and many suffer from methodological issues. The current study was designed with several methodological improvements to determine whether RF-EMF affects cortisol. Seventy-two participants completed a randomized, double-blind, counterbalanced provocation study where they were exposed to both active (2 W/kg peak SAR10g in head) and sham RF-EMF (0 W/kg peak SAR10g in head). Despite implementing several methodological improvements, the current study failed to find an effect of RF-EMF exposure on salivary cortisol concentration. This study provides a valuable direction for future research and stresses the importance of establishing and testing theoretically plausible interactions between low-level RF-EMF exposure, the human body, and IEI-EMF symptoms.

为了了解由电磁场引起的特发性环境不耐受症(IEI-EMF),有人认为测试射频电磁场(RF-EMF)对生物标志物的影响至关重要,因为它们比症状报告更客观。虽然没有明确证据表明射频电磁场暴露与生物标志物变化有关,但由于缺乏已知的生物效应机制,研究仍然有限,而且在很大程度上是推测性的。然而,有体外证据表明,皮质醇会受到加热的影响,由于RF-EMF会引起加热,因此RF-EMF暴露可能会通过热介导的过程增加皮质醇。如果皮质醇受到RF-EMF暴露的影响,它可能构成IEI-EMF更广泛病因学的一部分,其中RF-EMF诱导的生理(皮质醇)输入首先产生躯体感觉,然后通过预期或基于学习的过程促进产生症状。然而,调查RF-EMF暴露是否影响皮质醇的研究报告不一致,但大多是无效的结果,而且许多研究存在方法问题。目前的研究在确定RF-EMF是否影响皮质醇的方法上进行了一些改进。72名参与者完成了一项随机、双盲、平衡激发研究,他们暴露于活跃(头部峰值SAR10g 2 W/kg)和假RF-EMF(头部峰值SAR10g 0 W/kg)。尽管实施了一些方法上的改进,目前的研究未能发现射频电磁场暴露对唾液皮质醇浓度的影响。这项研究为未来的研究提供了一个有价值的方向,并强调了建立和测试低水平RF-EMF暴露、人体和IEI-EMF症状之间理论上合理的相互作用的重要性。
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引用次数: 0
Dual Evaluation and Spatial Analysis of RF-EMF Exposure in 5G: Theoretical Extrapolations and Direct Measurements 5G射频电磁场暴露的双重评估和空间分析:理论外推和直接测量
IF 1.2 3区 生物学 Q3 BIOLOGY Pub Date : 2025-08-20 DOI: 10.1002/bem.70020
Alberto Najera, Alvaro Villaescusa-Tebar, Jesus Gonzalez-Rubio, Concepcion Garcia-Pardo

This study evaluates radiofrequency electromagnetic field (RF-EMF) exposure in 5G networks using a dual approach that combines theoretical extrapolations and direct measurements in diverse semiurban and urban environments, specifically on the campus of the Polytechnic University of Valencia. Measurements were conducted using personal exposimeters under active traffic conditions on the 5G network, complemented by a code-selective measurement system based on an R&S TSME6 scanner. This approach enabled the calculation of maximum theoretical exposure by detailed analysis of 5G signals and the capture of key parameters such as cell ID and beam indices at 16 representative points across the campus. For precise spatial visualization, Kriging interpolation techniques in ArcGIS were employed to generate continuous exposure maps illustrating the spatial distribution of RF-EMF in the study area. The results indicate that both the extrapolated theoretical values and measured levels align with the limits recommended by the ICNIRP, even under high data demand scenarios, supporting current safety assessments of 5G infrastructure regarding electromagnetic exposure. The correlation between theoretical and instantaneous exposures validates the applied methodology and its effectiveness in assessing exposure in diverse environments. This study provides a robust framework for future research and highlights the importance of continuous monitoring to ensure public safety during the deployment of new telecommunications infrastructure in urban areas. Bioelectromagnetics. 00:00–00, 2025. © 2025 Bioelectromagnetics Society.

本研究采用双重方法评估5G网络中的射频电磁场(RF-EMF)暴露,该方法将理论推断和直接测量结合在不同的半城市和城市环境中,特别是在瓦伦西亚理工大学校园内。测量是在5G网络的主动交通条件下使用个人曝光仪进行的,辅以基于R&;S TSME6扫描仪的代码选择测量系统。这种方法可以通过详细分析5G信号和捕获关键参数(如小区ID和校园16个代表性点的波束指数)来计算最大理论暴露。为了实现精确的空间可视化,利用ArcGIS中的Kriging插值技术生成研究区RF-EMF空间分布的连续暴露图。结果表明,即使在高数据需求情景下,外推的理论值和测量水平都符合ICNIRP建议的限值,支持当前5G基础设施关于电磁暴露的安全评估。理论暴露和瞬时暴露之间的相关性验证了应用方法及其在评估不同环境下暴露的有效性。这项研究为未来的研究提供了一个强有力的框架,并强调了在城市地区部署新的电信基础设施期间持续监测以确保公共安全的重要性。生物电磁学。00:00 - 00,2025。©2025生物电磁学学会。
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引用次数: 0
5G RF EMF Spectral Exposure Assessment in Four European Countries 四个欧洲国家的5G射频电磁场频谱暴露评估
IF 1.2 3区 生物学 Q3 BIOLOGY Pub Date : 2025-08-20 DOI: 10.1002/bem.70019
Kenneth Deprez, Bram Stroobandt, Adriana Fernandes Veludo, Zsuzsanna Vecsei, Peter Pal Necz, Piotr Politański, Leen Verloock, Kinga Polanska, György Thuróczy, Martin Röösli, David Plets, Wout Joseph

This study assesses the exposure to 5G radio frequency electromagnetic fields (RF EMF) across four European countries. Spot measurements were conducted indoor and outdoor in both public spaces and educational institutions, encompassing urban and rural environments. In total, 146 measurements were performed in 2023, divided over Belgium (47), Switzerland (38), Hungary (30) and Poland (31). At 34.9% of all measurement locations a 5G connection to 3.6 GHz was established. The average cumulative incident power density (Savg) and maximum cumulative incident power density (Smax) were determined, for both “background” exposure (no 5G user equipment; No UE) and worst-case exposure (maximum downlink with 5G user equipment; Max DL). Furthermore, 3.6 GHz 5G-specific average Savg,5G and maximum Smax,5G incident power density are considered as well. For the No UE scenario, the highest Smax is 17.6 mW/m2, while for the Max DL, the highest Smax is 23.3 mW/m2. Both values are well within the ICNIRP guidelines. The highest Smax,5G measured over all countries and scenarios was 10.4 mW/m2, which is 3.2% of the frequency-specific ICNIRP guidelines. Additionally, a comparison was made between big cities, secondary cities, and villages for all four countries. The ratio of power density measured in rural areas was significantly lower than in urban areas (−4.8 to −10.4 dB). Under LOS conditions, the average incident power density was 2.3 mW/m2, whereas under NLOS conditions, the average incident power density decreases to 0.9 mW/m2. Furthermore, the relative variation increases under NLOS scenarios. Lastly, an analysis was performed regarding the power density in educational institutions compared to all other measurement locations, both indoors and outdoors for the different city types. The measured incident power density is not extensively lower in or around schools compared to public places, neither in the big cities, secondary cities, or the villages.

这项研究评估了四个欧洲国家的5G射频电磁场(RF EMF)暴露情况。现场测量在公共空间和教育机构的室内和室外进行,包括城市和农村环境。2023年总共进行了146次测量,分别在比利时(47次)、瑞士(38次)、匈牙利(30次)和波兰(31次)进行。在所有测量地点的34.9%建立了3.6 GHz的5G连接。确定了“背景”曝光(无5G用户设备;无UE)和最坏情况曝光(5G用户设备最大下行链路;最大DL)的平均累积入射功率密度(Savg)和最大累积入射功率密度(Smax)。此外,还考虑了3.6 GHz 5G特定平均Savg、5G和最大Smax、5G入射功率密度。No UE情景最大Smax为17.6 mW/m2, Max DL情景最大Smax为23.3 mW/m2。这两个值都完全符合ICNIRP的指导方针。在所有国家和场景中测量的5G最高Smax为10.4 mW/m2,这是特定频率ICNIRP指南的3.2%。此外,还对这四个国家的大城市、二线城市和乡村进行了比较。农村地区测得的功率密度比显著低于城市地区(- 4.8 dB至- 10.4 dB)。在LOS条件下,平均入射功率密度为2.3 mW/m2,而在NLOS条件下,平均入射功率密度降至0.9 mW/m2。此外,在NLOS情景下,相对变化增加。最后,对不同城市类型的教育机构与所有其他测量地点(室内和室外)的功率密度进行了分析。实测的入射功率密度在学校内或学校周围并没有明显低于公共场所,无论是在大城市、二线城市还是农村。
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引用次数: 0
Traceable Assessment of the Absorbed Power Density of Body Mounted Devices at Frequencies Above 10 GHz 频率高于10ghz的车载设备吸收功率密度的可追溯评估
IF 1.2 3区 生物学 Q3 BIOLOGY Pub Date : 2025-08-13 DOI: 10.1002/bem.70018
Ninad Chitnis, Fariba Karimi, Sven Kühn, Arya Fallahi, Andreas Christ, Niels Kuster

In this study, a comprehensive approach for the experimental assessment of the absorbed power density (APD) is developed. The method includes several novel components: (i) a specialized probe, (ii) a composite phantom, (iii) a reconstruction technique, (iv) a calibration method, and (v) a validation process. The described solution has been developed for the frequency range from 24 to 30 GHz, but can be extended to all frequency bands between 10 and 45 GHz. A novel composite phantom emulates the reflection and transmission coefficients of human skin for propagating and evanescent modes, while its increased penetration depth, in comparison to dermis tissue, enables the measurement of the induced electromagnetic fields (EMFs) with a new miniaturized dosimetric broadband probe. The implementation has a wide dynamic range and sufficient spatial resolution to use it for type approval of mobile devices. Its probe is calibrated with low uncertainty in a novel, traceable setup. A set of reference antennas with known numerical target values for the APD has been compiled to validate the measurement system. The validation demonstrates that the deviation is within the expanded uncertainty of 1.6 dB for pAPD and � � < $lt $ 1.5 dB for psAPD.

在本研究中,提出了一种综合评估吸收功率密度(APD)的实验方法。该方法包括几个新组件:(i)专用探针,(ii)复合模体,(iii)重建技术,(iv)校准方法,以及(v)验证过程。所描述的解决方案是为24至30 GHz的频率范围开发的,但可以扩展到10至45 GHz之间的所有频段。一种新型复合模体模拟了人类皮肤的反射和透射系数,用于传播和消失模式,而与真皮组织相比,它的穿透深度增加,可以用一种新的小型化剂量测量宽带探针测量感应电磁场(emf)。该实现具有广泛的动态范围和足够的空间分辨率,可用于移动设备的类型批准。它的探针在一种新颖的、可追溯的设置中以低不确定度校准。编制了一组已知APD数值目标值的参考天线来验证测量系统。验证表明,pAPD和<的偏差在1.6 dB的扩展不确定度范围内;$lt $ 1.5 dB用于psAPD。
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引用次数: 0
Can Theta Burst Electromagnetic Fields Disrupt Learning in Planaria? Evidence of Impaired Fear-Conditioned Responses θ脉冲电磁场会干扰涡虫的学习吗?恐惧条件反应受损的证据
IF 1.2 3区 生物学 Q3 BIOLOGY Pub Date : 2025-07-31 DOI: 10.1002/bem.70017
Kassra Ghassemkhani, Blake T. Dotta

This study explored the impact of low-intensity theta burst patterned electromagnetic fields (TBEMF) on fear-related learning in the flatworm species Planaria, a simple model organism known for its regenerative properties and ability to demonstrate basic learning behaviors. Planaria were exposed to an aversive stimulus (light) in a T-maze, and changes in their behavior, including time taken to select an arm and preferred arm selections, were assessed over the course of several days. The TBEMF consisted of five pulsed bursts at 100 Hz with alternating amplitudes and an intensity of 1 μT. In the group exposed to aversive light, a significant decrease in preferred arm selections was observed (p < 0.001), indicating that the planaria successfully learned to avoid the arm associated with the aversive stimulus. However, planaria exposed to TBEMF, either before or after the light exposure phase, did not show the same behavioral adaptation, as their arm selections remained stable, indicating that no fear learning occurred. These findings suggest that TBEMF disrupts the processes involved in fear-related learning, likely by interfering with theta rhythm-dependent mechanisms that are crucial for memory encoding and retrieval. Further exploration of EMF's effects on more complex organisms could reveal additional insights into its broader applications and implications for both basic neuroscience and clinical practice. Bioelectromagnetics. 00:00–00, 2025. © 2025 Bioelectromagnetics Society.

本研究探讨了低强度的θ波脉冲模式电磁场(tbef)对扁虫物种涡虫的恐惧相关学习的影响,涡虫是一种简单的模式生物,以其再生特性和展示基本学习行为的能力而闻名。在t型迷宫中,涡虫暴露在厌恶刺激(光)中,并在几天的过程中评估它们的行为变化,包括选择手臂和首选手臂的时间。tbef由5次100 Hz交变振幅、强度为1 μT的脉冲爆发组成。在暴露于厌恶光线的组中,观察到首选手臂选择显着减少(p < 0.001),这表明涡虫成功地学会了避开与厌恶刺激相关的手臂。然而,无论是在光暴露阶段之前还是之后,暴露于TBEMF的涡虫都没有表现出相同的行为适应,因为它们的手臂选择保持稳定,表明没有发生恐惧学习。这些发现表明,TBEMF可能通过干扰对记忆编码和检索至关重要的θ节奏依赖机制,扰乱了与恐惧相关的学习过程。进一步探索电磁场对更复杂生物体的影响,可以揭示其在基础神经科学和临床实践方面的更广泛应用和影响。生物电磁学。00:00 - 00,2025。©2025生物电磁学学会。
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引用次数: 0
Investigation of Viral Inactivation by High Peak Power Microwave (HPPM) Exposure in Solution 高峰值功率微波(HPPM)对溶液中病毒灭活作用的研究
IF 1.8 3区 生物学 Q3 BIOLOGY Pub Date : 2025-07-29 DOI: 10.1002/bem.70015
Jody C. Cantu, Ibtissam Echchgadda, Joseph W. Butterworth, Jason A. Payne, Leland R. Johnson, David A. Freeman, Weston C. Williams, Brad W. Hoff, Robert J. Thomas, William P. Roach, Bennett L. Ibey

The recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic had a tremendous impact on human life and global economics, motivating the invention of technology that can limit the spread of the virus from human to human in public areas. One candidate for such a purpose is radio frequency (RF) radiation, which was previously suggested to have a significant impact on viral integrity at exposure levels considered non-damaging to humans. However, these publications provided a limited explanation of the mechanism of action resulting in viral inactivation during RF exposure. One hypothesis was that structure resonance energy transfer (SRET) was occurring between the incident RF waves and the viral particle, which is highly dependent on the incident electric field strength. In this paper, we report exposures of bovine coronavirus (BCoV) to high peak power microwave (HPPM) pulses to validate the dependence of viral rupture on peak electric field as a critical parameter driving SRET. We tested 0.1–1.5 MW, 2 µs pulsed exposures of viral-containing buffer at 2.8, 5.6, 8.5, and 9.3 GHz up to 100,000 pulses and found no evidence of clinically significant E-field dependent decreases in viral infectivity. The findings reported in this manuscript do not support the hypothesis that SRET is a dominant mechanism behind RF-induced viral inactivation. Bioelectromagnetics. 00:00–00, 2025. © 2025 Published 2025. This article is a U.S. Government work and is in the public domain in the USA.

最近的严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)大流行对人类生活和全球经济产生了巨大影响,促使人们发明了可以在公共场所限制病毒在人与人之间传播的技术。这种目的的一个候选是射频(RF)辐射,以前认为,在被认为对人体无害的暴露水平下,射频辐射对病毒完整性有重大影响。然而,这些出版物对射频暴露期间导致病毒失活的作用机制提供了有限的解释。一种假设认为,在入射射频波和病毒粒子之间发生了结构共振能量转移(SRET),这种转移高度依赖于入射电场强度。在本文中,我们报道了牛冠状病毒(BCoV)暴露于峰值功率微波(HPPM)脉冲中,以验证病毒破裂与峰值电场作为驱动SRET的关键参数的依赖性。我们测试了0.1-1.5 MW, 2µs脉冲暴露于含病毒缓冲液2.8,5.6,8.5和9.3 GHz高达100,000脉冲,没有发现临床显著的e场依赖性病毒传染性降低的证据。本文报道的研究结果不支持SRET是rf诱导的病毒失活背后的主要机制的假设。生物电磁学。00:00 - 00,2025。©2025出版于2025。这篇文章是美国政府的作品,在美国属于公有领域。
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引用次数: 0
Effects of Whole-Body Exposure to Pulsed Electromagnetic Field at Different Frequencies on Knee Osteoarthritis 不同频率脉冲电磁场对膝关节骨性关节炎的影响
IF 1.8 3区 生物学 Q3 BIOLOGY Pub Date : 2025-07-29 DOI: 10.1002/bem.70016
Xiaotian Yang, Xuqing Li, Haixin Song, Tao Wu, Jianhua Li, Chengqi He

This study aimed to investigate the efficacy of pulsed electromagnetic field (PEMF) at different frequencies during knee osteoarthritis (OA) progression. Ten-week-old male wild-type (WT) mice undergoing the destabilization of the medial meniscus (DMM) surgery were randomly divided into four groups (n = 10 each) respectively: DMM, DMM with three PEMF exposure (8, 50, or 75 Hz). PEMF (3.8 mT, 1 h/day) at different frequencies was applied for 4 weeks. Von Frey test, histological assessment, RT-PCR, immunohistochemical staining, and microcomputed tomography (CT) were performed. PEMF at three frequencies (8, 50, and 75 Hz) decreased the Osteoarthritis Research Society International (OARSI) scores to different extents compared to the DMM group. The mRNA and protein expressions of MMP13 and aggrecan (Acan) in cartilage were improved in three PEMF groups; PEMF at 50 and 75 Hz had better positive effects than PEMF at 8 Hz. The increased synovitis was attenuated by 75 Hz PEMF. 75 and 50 Hz PEMF groups had a beneficial effect on increasing 50% paw withdrawal threshold (PWT) compared with the DMM group. Micro-CT analysis showed that 75 Hz PEMF group, compared with DMM group, increased trabecular thickness (Tb.Th) of femur and bone volume/total volume (BV/TV) of femoral condyle and femur, and decreased bone surface/bone volume (BS/BV) of tibia. The study demonstrated that PEMF at 75 Hz could attenuate symptomatic and structural knee OA progression. Bioelectromagnetics. 00:00–00, 2025. © 2025 Bioelectromagnetics Society.

本研究旨在探讨不同频率脉冲电磁场(PEMF)在膝关节骨关节炎(OA)进展中的疗效。10周龄雄性野生型(WT)小鼠接受内侧半月板失稳(DMM)手术,随机分为四组(每组n = 10): DMM组,DMM与三次PEMF暴露(8,50或75 Hz)。使用不同频率的PEMF (3.8 mT, 1 h/天),持续4周。进行Von Frey试验、组织学评估、RT-PCR、免疫组织化学染色、微计算机断层扫描(CT)。与DMM组相比,三个频率(8、50和75 Hz)的PEMF在不同程度上降低了国际骨关节炎研究学会(OARSI)评分。三个PEMF组软骨组织中MMP13和聚集蛋白(Acan)的mRNA和蛋白表达均有改善;50和75 Hz的脉冲电场比8 Hz的脉冲电场有更好的积极效果。加重的滑膜炎经75 Hz脉冲电场减弱。与DMM组相比,75和50 Hz的PEMF组对提高50%的爪脱阈值(PWT)有有益的作用。显微ct分析显示,与DMM组相比,75 Hz PEMF组股骨骨小梁厚度(Tb.Th)、股骨髁和股骨骨体积/总体积(BV/TV)增加,胫骨骨表面积/骨体积(BS/BV)减少。研究表明,75 Hz的PEMF可以减轻症状性和结构性膝OA进展。生物电磁学。00:00 - 00,2025。©2025生物电磁学学会。
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引用次数: 0
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