Pub Date : 2017-11-10DOI: 10.4172/2327-5162.1000254
M. Baba, S. Yakubo, E. Fukuda, Yukiko Ueda, Tomohiro Hattori, E. Shiba, M. Soma, Y. Arashima, T. Namiki
Introduction: Randomized usual-case controlled studies on Japanese dementia patients with behavioral and psychological symptoms were conducted to examine the effects of Kampo medicine Yokukan-San (YKS) on the behavioral and psychological symptoms of dementia (BPSD). These studies showed that YKS is effective in treating BPSD. Yokukan-San-Ka-Chimpi-Hange is a Kampo medicine made by adding dried citrus peel and pinellia tuber to YKS. In Japan, we usually administer Yokukan-San-Ka-Chimpi-Hange as Kracie Yokukan-San-Ka-Chimpi-Hange extract granules (KB-83), produced by Kracie Pharma, Ltd. (Tokyo, Japan). Methods: We investigated 3 trials carried out on the use of KB-83 for the treatment of severe dementia in elderly. Results: KB-83 showed no change in core symptoms after administration in cases of dementia, but significant improvements in BPSD were reported. KB-83 was particularly effective in treating aggressive symptoms such as restlessness or abusive language. Conclusion: In the treatment of dementia, we think that the administration of KB-83 is effective in mitigating the BPSD, and that further studies are need to investigate the effects of EK-83.
引言:对有行为和心理症状的日本痴呆症患者进行随机常规病例对照研究,以检验Kampo medicine Yokukan San(YKS)对痴呆症行为和心理特征(BPSD)的影响。这些研究表明YKS治疗BPSD是有效的。Yokukan San Ka Chimpi Hange是一种贡布药,通过在YKS中加入干柑橘皮和菠萝块茎制成。在日本,我们通常以Kracie Yokukan-San-Ka-Chimpi-Hange提取物颗粒(KB-83)的形式给药,该颗粒由Kracie Pharma,有限公司生产。方法:我们研究了KB-83治疗老年严重痴呆的3项试验。结果:KB-83在痴呆患者给药后核心症状没有变化,但BPSD有显著改善。KB-83在治疗烦躁不安或辱骂性语言等攻击性症状方面尤其有效。结论:在痴呆症的治疗中,我们认为给予KB-83可以有效地减轻BPSD,需要进一步研究EK-83的作用。
{"title":"Systematic Review: Effects of the Kampo Formula Yokukan-San-Ka-Chimpi-Hange on Behavioral and Psychological Symptoms of Dementia","authors":"M. Baba, S. Yakubo, E. Fukuda, Yukiko Ueda, Tomohiro Hattori, E. Shiba, M. Soma, Y. Arashima, T. Namiki","doi":"10.4172/2327-5162.1000254","DOIUrl":"https://doi.org/10.4172/2327-5162.1000254","url":null,"abstract":"Introduction: Randomized usual-case controlled studies on Japanese dementia patients with behavioral and psychological symptoms were conducted to examine the effects of Kampo medicine Yokukan-San (YKS) on the behavioral and psychological symptoms of dementia (BPSD). These studies showed that YKS is effective in treating BPSD. Yokukan-San-Ka-Chimpi-Hange is a Kampo medicine made by adding dried citrus peel and pinellia tuber to YKS. In Japan, we usually administer Yokukan-San-Ka-Chimpi-Hange as Kracie Yokukan-San-Ka-Chimpi-Hange extract granules (KB-83), produced by Kracie Pharma, Ltd. (Tokyo, Japan). \u0000Methods: We investigated 3 trials carried out on the use of KB-83 for the treatment of severe dementia in elderly. \u0000Results: KB-83 showed no change in core symptoms after administration in cases of dementia, but significant improvements in BPSD were reported. KB-83 was particularly effective in treating aggressive symptoms such as restlessness or abusive language. \u0000Conclusion: In the treatment of dementia, we think that the administration of KB-83 is effective in mitigating the BPSD, and that further studies are need to investigate the effects of EK-83.","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2327-5162.1000254","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48074786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-28DOI: 10.4172/2327-5162.1000253
M. Farooqui
Caner is a leading cause of death worldwide which requires a multidisciplinary treatment approach. Safety and efficacy of many of the modern therapies have been well established but still use of complementary and alternative medicines (CAM) are on rise among cancer patients. CAM decision making process is complex which is affected by many social and disease related variables. Prevalence based studies regarding CAM use reported a wide range of variation in percentage use of CAM among cancer patients which could be due to the way different studies defined CAM in their studies. Understanding CAM use decision making is crucial as it is highly individualized and revolves around several issues which can benefit patients and their care givers in treatment success.
{"title":"Complementary and Alternative Medicines (Cam) Use among Cancer Patients: An Overview and the Decision Making","authors":"M. Farooqui","doi":"10.4172/2327-5162.1000253","DOIUrl":"https://doi.org/10.4172/2327-5162.1000253","url":null,"abstract":"Caner is a leading cause of death worldwide which requires a multidisciplinary treatment approach. Safety and efficacy of many of the modern therapies have been well established but still use of complementary and alternative medicines (CAM) are on rise among cancer patients. CAM decision making process is complex which is affected by many social and disease related variables. Prevalence based studies regarding CAM use reported a wide range of variation in percentage use of CAM among cancer patients which could be due to the way different studies defined CAM in their studies. Understanding CAM use decision making is crucial as it is highly individualized and revolves around several issues which can benefit patients and their care givers in treatment success.","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":"6 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2327-5162.1000253","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41319226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-20DOI: 10.4172/2327-5162.1000249
Yi Wang, Zhongyan Liu, L. Cai, Ting Wang, Xiaoying Chen, Jing Zheng, Juxia Wang
Aim: The objective is to investigate the changes of serum IFGF23 and CFGF23 levels in patients with chronic kidney disease of 3-5 stage before and after treatment by Yishen Jiangzhuo Granules and its clinical significance. Methods: A subset of samples (n=76) from a cohort of patients with CKD of renal function between stage three and five. (Stage 3: n=37; stage 4: n=30; stage 5: n=9). The patients were treated in hospital or in clinic between October 2013 and April 2015 at the nephrology department of Fujian Provincial People's Hospital. Additionally, a total of 30 healthy volunteers were selected in this hospital during the same period as the normal control group. IFGF23, CFGF23 were detected by enzyme-linked immunosorbent assay (ELISA). Calcium (Ca), phosphorus (P), urea nitrogen (BUN), serum creatinine (Scr) was assessed by BECKMAN-C800 automatic biochemical analyzer. Urine creatinine was determined by Reversed Phase High Performance Liquid Chromatography. The endogenous creatinine clearance rate (Ccr) was calculated according to the simplified MDRD formula. Result: The expression levels of serum IFGF23 and CFGF23 did not change significantly before and after drug treatment. But the serum IFGF23 and CFGF23 expression level has been significantly increased in the CKD3 stage, while serum phosphorus levels has not yet increased. Compared with normal group, the expression level of serum IFGF23 and CFGF23 was significantly higher than that of the normal group before and after treatment. Both of them showed a tendency to increase gradually with the decrease of renal function, and the degree of increase of serum IFGF23 expression level was significantly higher than that of CFGF23. Scr and P levels were decreased in CKD 3-5 stage after treatment (P<0.05). In CKD 4-5 stage, after treatment, the serum calcium level was higher than that before treatment (P<0.05). In CKD 3-5 stage, after treatment, the Ccr was higher than that before treatment (P<0.05). Conclusion: IFGF23 increases rapidly with the decrease of Ccr and CFGF23 increases slowly with the decrease of Ccr. In the short term, Yishenjiangzhuo Granules cannot improve serum IFGF23 and CFGF23 levels in CKD 3-5 stage in patients, but it improves the renal function and the metabolism of calcium and phosphorus, and reduces the level of serum creatinine.
{"title":"The Effect of Yishen Jiangzhuo Granules on Serum IFGF23 and CFGF23 in Patients with Chronic Kidney Disease 3-5 Stage","authors":"Yi Wang, Zhongyan Liu, L. Cai, Ting Wang, Xiaoying Chen, Jing Zheng, Juxia Wang","doi":"10.4172/2327-5162.1000249","DOIUrl":"https://doi.org/10.4172/2327-5162.1000249","url":null,"abstract":"Aim: The objective is to investigate the changes of serum IFGF23 and CFGF23 levels in patients with chronic kidney disease of 3-5 stage before and after treatment by Yishen Jiangzhuo Granules and its clinical significance. \u0000Methods: A subset of samples (n=76) from a cohort of patients with CKD of renal function between stage three and five. (Stage 3: n=37; stage 4: n=30; stage 5: n=9). The patients were treated in hospital or in clinic between October 2013 and April 2015 at the nephrology department of Fujian Provincial People's Hospital. Additionally, a total of 30 healthy volunteers were selected in this hospital during the same period as the normal control group. IFGF23, CFGF23 were detected by enzyme-linked immunosorbent assay (ELISA). Calcium (Ca), phosphorus (P), urea nitrogen (BUN), serum creatinine (Scr) was assessed by BECKMAN-C800 automatic biochemical analyzer. Urine creatinine was determined by Reversed Phase High Performance Liquid Chromatography. The endogenous creatinine clearance rate (Ccr) was calculated according to the simplified MDRD formula. \u0000Result: The expression levels of serum IFGF23 and CFGF23 did not change significantly before and after drug treatment. But the serum IFGF23 and CFGF23 expression level has been significantly increased in the CKD3 stage, while serum phosphorus levels has not yet increased. Compared with normal group, the expression level of serum IFGF23 and CFGF23 was significantly higher than that of the normal group before and after treatment. \u0000Both of them showed a tendency to increase gradually with the decrease of renal function, and the degree of increase of serum IFGF23 expression level was significantly higher than that of CFGF23. Scr and P levels were decreased in CKD 3-5 stage after treatment (P<0.05). In CKD 4-5 stage, after treatment, the serum calcium level was higher than that before treatment (P<0.05). In CKD 3-5 stage, after treatment, the Ccr was higher than that before treatment (P<0.05). \u0000Conclusion: IFGF23 increases rapidly with the decrease of Ccr and CFGF23 increases slowly with the decrease of Ccr. In the short term, Yishenjiangzhuo Granules cannot improve serum IFGF23 and CFGF23 levels in CKD 3-5 stage in patients, but it improves the renal function and the metabolism of calcium and phosphorus, and reduces the level of serum creatinine.","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41820124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-09DOI: 10.4172/2327-5162-C1-028
T. E. Pressman
{"title":"Holosynthesis: the new radical joy approach","authors":"T. E. Pressman","doi":"10.4172/2327-5162-C1-028","DOIUrl":"https://doi.org/10.4172/2327-5162-C1-028","url":null,"abstract":"","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70260244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-06DOI: 10.4172/2327-5162.1000247
D. Gurn, J. Hudak, Šárka Tomková
Breathing is one of the basic life functions. High demands are placed on the respiratory system when increased value of power for example in sport. The main inspiratory muscle is the diaphragm, which performs this function in addition to other functions, mainly postural and sphincter. The aim of this study was to assess the effect on functional capacity of the lung after postural therapy. Trial involved 35 male elite athletes, 25 of which formed the experimental group and 10 was control group. Input and output measurements were identical and methodically divided into two main areas. Postural tests reported in the literature by prof. Kolar and spirometric test. The tests were carried out under constant conditions, and in the same time. The experimental group received postural training lasting six weeks. Comparing the results after completing postural training, we observed differences in postural execution like in spirometry tests in favor of the experimental group. Based on the results of our studies we suggest that postural training of diaphragm have a positive effect on the functional capacity of the lungs. Changes were not statistically significant at all endpoints. This may be caused by tested of elite athletes compared with the possible outcome of the general population. Individuality subjects and their psychosocial conditions during testing could also influence the outcome in a positive or negative direction.
{"title":"Influence of Postural Training of Diaphragm on Functional Lung Capacity","authors":"D. Gurn, J. Hudak, Šárka Tomková","doi":"10.4172/2327-5162.1000247","DOIUrl":"https://doi.org/10.4172/2327-5162.1000247","url":null,"abstract":"Breathing is one of the basic life functions. High demands are placed on the respiratory system when increased value of power for example in sport. The main inspiratory muscle is the diaphragm, which performs this function in addition to other functions, mainly postural and sphincter. The aim of this study was to assess the effect on functional capacity of the lung after postural therapy. Trial involved 35 male elite athletes, 25 of which formed the experimental group and 10 was control group. Input and output measurements were identical and methodically divided into two main areas. Postural tests reported in the literature by prof. Kolar and spirometric test. The tests were carried out under constant conditions, and in the same time. The experimental group received postural training lasting six weeks. Comparing the results after completing postural training, we observed differences in postural execution like in spirometry tests in favor of the experimental group. Based on the results of our studies we suggest that postural training of diaphragm have a positive effect on the functional capacity of the lungs. Changes were not statistically significant at all endpoints. This may be caused by tested of elite athletes compared with the possible outcome of the general population. Individuality subjects and their psychosocial conditions during testing could also influence the outcome in a positive or negative direction.","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2327-5162.1000247","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45034356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-09-14DOI: 10.4172/2327-5162.1000246
H. Yao
Background: Ionic detoxification (ID) or ionic water bath treatment is a simple alternative method to improve health but lacks scientific evidence. It is hypothesized that regular ID treatment can increase the excretion of toxic molecules from the body and improve metabolic disorders including obesity. Methods: To investigate the effect of ID treatment on high-fat diet-induced obesity and fatty liver, male Wistar rats were fed a low-fat control diet, a high-fat (HF) diet, or a HF diet with ID treatment (3 times/week) for 11 weeks. Triglyceride contents and fatty acid metabolic genes in perirenal adipose tissue and liver were determined. Results: Rats fed the HF diet had significantly higher body weight, liver weight, and adipose tissue (perirenal and epididymal) weight than did animals fed the low-fat diet. ID treatment significantly reduced body weight and perirenal adipose tissue weight induced by the HF diet. In addition, ID treatment reduced hepatic cholesterol and triglyceride contents. In liver, ID treatment reduced fatty acid synthesis (acetyl-CoA carboxylase and fatty acid synthase mRNA) more significantly than fatty acid oxidation (carnitine palmitoyl-transferase 1 and acyl CoA oxidase mRNA). In perirenal adipose tissue, ID treatment increased the lipolysis rate and reduced the triglyceride level. However, ID treatment had no significant effects on lipogenesis gene expression or adipose size in perirenal adipose tissue. Conclusions: The results of this study suggest that regular ID treatment may have beneficial effects on reducing obesity and fatty liver.
{"title":"Ionic Detoxification Reduces Obesity and Fatty Liver in Rats Fed a High- Fat Diet","authors":"H. Yao","doi":"10.4172/2327-5162.1000246","DOIUrl":"https://doi.org/10.4172/2327-5162.1000246","url":null,"abstract":"Background: Ionic detoxification (ID) or ionic water bath treatment is a simple alternative method to improve health but lacks scientific evidence. It is hypothesized that regular ID treatment can increase the excretion of toxic molecules from the body and improve metabolic disorders including obesity. \u0000Methods: To investigate the effect of ID treatment on high-fat diet-induced obesity and fatty liver, male Wistar rats were fed a low-fat control diet, a high-fat (HF) diet, or a HF diet with ID treatment (3 times/week) for 11 weeks. Triglyceride contents and fatty acid metabolic genes in perirenal adipose tissue and liver were determined. \u0000Results: Rats fed the HF diet had significantly higher body weight, liver weight, and adipose tissue (perirenal and epididymal) weight than did animals fed the low-fat diet. ID treatment significantly reduced body weight and perirenal adipose tissue weight induced by the HF diet. In addition, ID treatment reduced hepatic cholesterol and triglyceride contents. In liver, ID treatment reduced fatty acid synthesis (acetyl-CoA carboxylase and fatty acid synthase mRNA) more significantly than fatty acid oxidation (carnitine palmitoyl-transferase 1 and acyl CoA oxidase mRNA). In perirenal adipose tissue, ID treatment increased the lipolysis rate and reduced the triglyceride level. However, ID treatment had no significant effects on lipogenesis gene expression or adipose size in perirenal adipose tissue. \u0000Conclusions: The results of this study suggest that regular ID treatment may have beneficial effects on reducing obesity and fatty liver.","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":"6 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2327-5162.1000246","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43678561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-09-06DOI: 10.4172/2327-5162.1000245
A. Narayan
Cardiovascular Disease (CVD), which includes heart attacks, stroke, and other cardiovascular diseases, are the number one cause of death in the United States. Data gathered from certain lab tests utilized as part of an early detection and prevention strategy can be used to gauge the efficacy of preventative measures in an effort to halt or slow the progress of the CVD. Acute phase reactants are proteins that increase or decrease in the presence of inflammatory stimuli. The most common acute phase reactant tests are Erythrocyte Sedimentation Rate (ESR), CReactive Protein (CRP), Fibrinogen, and Ferritin. of these four tests the most common tests currently used in conventional medicine are ESR and CRP. Fibrinogen, which originates in the liver, is a glycoprotein in vertebrates that helps in the formation of blood clots. Fibrinogen levels rise in the following conditions: Inflammation, tissue damage/trauma, infection, cancer, acute coronary syndrome, strokes, and inflammatory conditions. Fibrinogen tests are underutilized in conventional medicine. They are often used after a cardiovascular incident has occurred or if symptoms are severe enough to warrant a test. There is sufficient evidence which shows that fibrinogen levels slowly begin to rise long before a heart attack or stroke and may even be reflective of the severity of subclinical atherosclerotic conditions. Traditional Chinese Medicine (TCM) and other preventative natural medical systems have treatments which reduce or normalize Fibrinogen levels, thereby, preventing the progression of symptoms that can lead to more serious cardiovascular occurrences in the future. This article will review published studies that confirm natural remedies effectively lower fibrinogen levels.
{"title":"Natural Remedies Lower Fibrinogen Levels in the Prevention ofAtherosclerosis","authors":"A. Narayan","doi":"10.4172/2327-5162.1000245","DOIUrl":"https://doi.org/10.4172/2327-5162.1000245","url":null,"abstract":"Cardiovascular Disease (CVD), which includes heart attacks, stroke, and other cardiovascular diseases, are the \u0000 number one cause of death in the United States. Data gathered from certain lab tests utilized as part of an early \u0000 detection and prevention strategy can be used to gauge the efficacy of preventative measures in an effort to halt or \u0000 slow the progress of the CVD. Acute phase reactants are proteins that increase or decrease in the presence of \u0000 inflammatory stimuli. The most common acute phase reactant tests are Erythrocyte Sedimentation Rate (ESR), CReactive \u0000 Protein (CRP), Fibrinogen, and Ferritin. of these four tests the most common tests currently used in \u0000 conventional medicine are ESR and CRP. Fibrinogen, which originates in the liver, is a glycoprotein in vertebrates \u0000 that helps in the formation of blood clots. Fibrinogen levels rise in the following conditions: Inflammation, tissue \u0000 damage/trauma, infection, cancer, acute coronary syndrome, strokes, and inflammatory conditions. Fibrinogen tests \u0000 are underutilized in conventional medicine. They are often used after a cardiovascular incident has occurred or if \u0000 symptoms are severe enough to warrant a test. There is sufficient evidence which shows that fibrinogen levels \u0000 slowly begin to rise long before a heart attack or stroke and may even be reflective of the severity of subclinical \u0000 atherosclerotic conditions. Traditional Chinese Medicine (TCM) and other preventative natural medical systems have \u0000 treatments which reduce or normalize Fibrinogen levels, thereby, preventing the progression of symptoms that can \u0000 lead to more serious cardiovascular occurrences in the future. This article will review published studies that confirm \u0000 natural remedies effectively lower fibrinogen levels.","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46823705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-22DOI: 10.4172/2327-5162-C1-026
R. Jaffe
{"title":"Acupuncture: Workshop on how and why it works","authors":"R. Jaffe","doi":"10.4172/2327-5162-C1-026","DOIUrl":"https://doi.org/10.4172/2327-5162-C1-026","url":null,"abstract":"","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70260440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-22DOI: 10.4172/2327-5162-C1-025
Jingduan Yang
{"title":"Integration of acupuncture with modern medicine","authors":"Jingduan Yang","doi":"10.4172/2327-5162-C1-025","DOIUrl":"https://doi.org/10.4172/2327-5162-C1-025","url":null,"abstract":"","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70260413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-27DOI: 10.4172/2327-5162.1000244
Zhou Qiao, L. Jian, Xin Ling, Song Qian, Guo Jin-chen, Huang Dan
Background: Traditional Chinese medicine (TCM) is increasingly widely used as a complementary approach for the treatment of osteoarthritis. In this paper, we examined the implicit prescription patterns behind the Chinese medicinal formulae by using association rules mining and clustering analysis, so as to explore the compatibility regularity of Chinese medicinal prescription in the treatment or control of osteoarthritis. Methods: This study was based on a participant survey conducted in First Affiliated Hospital of Anhui University of Chinese Medicine. The Chinese medicinal prescriptions of inpatients with osteoarthritis were from June 2012 to June 2016. TCM was listed according to the selected medicinal formulae and the added information was organized to establish a database. The association rules and clustering are conducted on SPSS Modeler 14.2. An initial statistical analysis was carried out to categorize the herbs according to their medicinal types, dosage, natures, flavors, channel tropism, and functions. Based on the categorization, the frequencies of occurrences were computed. At the same time, the relationship between TCM and immune and inflammatory markers was analyzed. Results: The main features from the formulae data are: (1) Warm or cold herbs in the Five Properties category are the most frequently prescribed in the 3609 medicinal formulae. Sweet or bitter herbs in the Five Flavors category in which affinity to the Spleen meridian also are the most frequently prescribed in the 3609 medicinal formulae. (2) Herbs with blood-activating and stasis-resolving, tonifying and replenishing medicinal, water-disinhibiting damppercolating, heat-clearing and detoxicating or expelling wind-damp functions that are frequently prescribed; (3) Association rule analysis extracted three frequently used pairs of herbs, which are Red flower and Tao Ren, Pu Gong Ying and Bai Hua She She Cao, Fu Ling and Ze Xie. (4) Association rule between TCM and Immunoinflammation Index showed that Du Huo and Chen Pi was associated with increased super oxide dismutase enzyme. Mai Ya and Dan Shen was associated with decreased high-sensitivity C-reactive protein, erythrocyte sedimentation rate, complement C3, complement C4, and Ig(A). Mai Ya and Fu Ling were associated with decreased IgM. Conclusions: The results indicate that there is a close relationship between osteoarthritis and spleen dysfunctions. These prescriptions focus on herbs that replenishing qi and fortifying the spleen and blood-activating and stasis-resolving. It can also dry dampness to fortify the spleen and clear heat and detoxicating. Meanwhile, he use of tonifying and replenishing herbs and spleen-strengthening herbs also forms a basic pattern of the prescriptions.
{"title":"Exploratory Compatibility Regularity of Chinese Medicinal Prescription in Treating Osteoarthritis","authors":"Zhou Qiao, L. Jian, Xin Ling, Song Qian, Guo Jin-chen, Huang Dan","doi":"10.4172/2327-5162.1000244","DOIUrl":"https://doi.org/10.4172/2327-5162.1000244","url":null,"abstract":"Background: Traditional Chinese medicine (TCM) is increasingly widely used as a complementary approach for the treatment of osteoarthritis. In this paper, we examined the implicit prescription patterns behind the Chinese medicinal formulae by using association rules mining and clustering analysis, so as to explore the compatibility regularity of Chinese medicinal prescription in the treatment or control of osteoarthritis. \u0000Methods: This study was based on a participant survey conducted in First Affiliated Hospital of Anhui University of Chinese Medicine. The Chinese medicinal prescriptions of inpatients with osteoarthritis were from June 2012 to June 2016. TCM was listed according to the selected medicinal formulae and the added information was organized to establish a database. The association rules and clustering are conducted on SPSS Modeler 14.2. An initial statistical analysis was carried out to categorize the herbs according to their medicinal types, dosage, natures, flavors, channel tropism, and functions. Based on the categorization, the frequencies of occurrences were computed. At the same time, the relationship between TCM and immune and inflammatory markers was analyzed. \u0000Results: The main features from the formulae data are: (1) Warm or cold herbs in the Five Properties category are the most frequently prescribed in the 3609 medicinal formulae. Sweet or bitter herbs in the Five Flavors category in which affinity to the Spleen meridian also are the most frequently prescribed in the 3609 medicinal formulae. (2) Herbs with blood-activating and stasis-resolving, tonifying and replenishing medicinal, water-disinhibiting damppercolating, heat-clearing and detoxicating or expelling wind-damp functions that are frequently prescribed; (3) Association rule analysis extracted three frequently used pairs of herbs, which are Red flower and Tao Ren, Pu Gong Ying and Bai Hua She She Cao, Fu Ling and Ze Xie. (4) Association rule between TCM and Immunoinflammation Index showed that Du Huo and Chen Pi was associated with increased super oxide dismutase enzyme. Mai Ya and Dan Shen was associated with decreased high-sensitivity C-reactive protein, erythrocyte sedimentation rate, complement C3, complement C4, and Ig(A). Mai Ya and Fu Ling were associated with decreased IgM. \u0000Conclusions: The results indicate that there is a close relationship between osteoarthritis and spleen dysfunctions. These prescriptions focus on herbs that replenishing qi and fortifying the spleen and blood-activating and stasis-resolving. It can also dry dampness to fortify the spleen and clear heat and detoxicating. Meanwhile, he use of tonifying and replenishing herbs and spleen-strengthening herbs also forms a basic pattern of the prescriptions.","PeriodicalId":90094,"journal":{"name":"Alternative & integrative medicine","volume":" ","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48265120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}