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Type A Aortic Dissection Presenting with Acute Lower Extremity Vascular Insufficiency in the Absence of Chest Pain 无胸痛的A型主动脉夹层表现为急性下肢血管功能不全
Pub Date : 2012-01-01 DOI: 10.4137/OJCS.S8042
Thomas J. Earl, A. Poppas
We report a case of a 53 year-old man with a history of hypertension presenting with acute left lower extremity parasthesias and pulselessness initially presumed to be secondary to arterial thrombosis or embolism. Work-up included a transthoracic echocardiogram which revealed an aortic dissection at the level of the aortic root extending to the visualized portions of the descending aorta. Type A aortic dissections are relatively rare, with the vast majority of patients presenting with chest pain. Timely diagnosis of Type A aortic dissections are critical as to facilitate rapid surgical repair. To our knowledge, this is the first report of a painless Type A aortic dissection presenting with isolated lower extremity vascular insufficiency and demonstrates the potential role of transthoracic echocardiography as a rapid, non-invasive bedside modality in visualizing Type A aortic dissections.
我们报告一例53岁男性高血压病史,表现为急性左下肢感觉异常和无脉搏,最初推测是继发于动脉血栓形成或栓塞。检查包括经胸超声心动图,显示主动脉根部有主动脉夹层,延伸至降主动脉可见部分。A型主动脉夹层相对罕见,绝大多数患者表现为胸痛。及时诊断A型主动脉夹层是促进快速手术修复的关键。据我们所知,这是第一例无痛的a型主动脉夹层,表现为孤立的下肢血管功能不全,并证明了经胸超声心动图作为一种快速、无创的床边方式在观察a型主动脉夹层中的潜在作用。
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引用次数: 0
Intra-Aortic Balloon Pump Entrapment in a Nonatherosclerotic Common Iliac Artery 非动脉粥样硬化性髂总动脉内球囊泵夹持
Pub Date : 2011-01-01 DOI: 10.4137/OJCS.S7688
F. Sabzi, A. Zokaei, Abdolrasoul Moloudi, S. Dabiri
Use of an intra-aortic balloon pump (IABP) is helpful for maintaining hemodynamic stability in patients with low cardiac output and compromised left ventricular function undergoing coronary artery bypass grafting. Although the incidence of complications has decreased significantly as experience with the device has increased, IABP use still carries a risk of complications. The most common complication is limb ischemia, mainly as a result of IABP entrapment and thromboembolism. Here we report a case of IABP entrapment in a nonatherosclerotic common iliac artery where forced removal caused fracture of the catheter.
使用主动脉内球囊泵(IABP)有助于维持低心输出量和左心室功能受损患者行冠状动脉旁路移植术的血流动力学稳定性。虽然随着设备使用经验的增加,并发症的发生率显著降低,但IABP的使用仍然存在并发症的风险。最常见的并发症是肢体缺血,主要是由于IABP包裹和血栓栓塞。在此,我们报告一例IABP卡在非动脉粥样硬化的髂总动脉中,强行移除导致导管骨折。
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引用次数: 4
Prevalence and Predisposing Factors of Atrial Fibrillation in a Multi-Ethnic Society: The Impact of Racial Differences in Bahrain 多民族社会中房颤的患病率和易感因素:巴林种族差异的影响
Pub Date : 2011-01-01 DOI: 10.4137/OJCS.S8032
Taysir Garadah, Saleh Gabani, M. A. Alawi, Ahmed A. Abu-Taleb
Background The prevalence and epidemiological data of atrial fibrillation (AF) among multi-ethnic populations is less well studied worldwide. Aim Evaluation of the prevalence and predisposing factors of AF in patients who were admitted to acute medical emergencies (ER) in Bahrain over the period of one year. Methods Two hundred and fifty three patients with onset of AF were studied. The mean difference of biochemical data and clinical characteristics between Middle Eastern (ME) and sub continental (SC) patients was evaluated. The odds ratio of different predisposing factors for the development of clinical events in AF patients was assessed using multiple logistic regression analysis. Results Out of 7,450 patients that were admitted to ER over one year, 253 had AF based on twelve leads Electrocardiogram (ECG), with prevalence of 3.4%. In the whole study, the mean age was 59.45 ± 18.27 years, with 164 (65%) male. There were 150 ME patients (59%), and 107 (41%) SC, 55 (22%) were Indian (IND) and 48 (19%) were South Asian (SA). In the whole study clinical presentation was of 48% for palpitation, pulmonary edema was of 14%, angina pectoris on rest of 12%, 10% had embolic phenomena, 6% had dizziness, and 7% were asymptomatic. The odds ratio of different variables for occurrence of clinical events in the study was positive of 2.2 for history of hypertension, 1.8 for sickle cell disease, 1.2 for high body mass index (BMI) >30, 1.1 for mitral valve disease. The ME patients, compared with SC, were older, had significantly higher body mass index, higher history of rheumatic valve disease, sickle cell disease with high level of uric acid and lower hemoglobin. The history of hypertension, DM and smoking was higher among the SC patients. The rate of thyroid disease was equal in both groups. Conclusion The prevalence of atrial fibrillation was 3.4% with male predominance of 65%. Patients of sub continental origin were younger with a significantly high history of hypertension and ischemic heart disease. The patients of Middle Eastern origin had significantly high rate of rheumatic heart disease, and sickle cell disease. The history of hypertension was the most important independent clinical predictor of adverse events in patients presented with AF.
背景在世界范围内,对多民族人群房颤(AF)的患病率和流行病学资料研究较少。目的评价巴林一年内急诊(ER)患者房颤患病率及易感因素。方法对253例AF发病患者进行分析。评估中东(ME)和亚大陆(SC)患者的生化数据和临床特征的平均差异。采用多元logistic回归分析评估不同易感因素对房颤患者临床事件发生的优势比。结果7450例急诊住院1年以上患者中,12导联心电图(ECG)显示房颤253例,患病率为3.4%。整个研究的平均年龄为59.45±18.27岁,其中男性164例(65%)。ME患者150例(59%),SC患者107例(41%),印度(IND) 55例(22%),南亚(SA) 48例(19%)。在整个研究中,临床表现为心悸占48%,肺水肿占14%,心绞痛占12%,有栓塞现象占10%,头晕占6%,无症状占7%。研究中临床事件发生的不同变量比值比为正,高血压史为2.2,镰状细胞病为1.8,高体重指数(BMI)为1.2,二尖瓣疾病为1.1。与SC患者相比,ME患者年龄较大,体重指数明显较高,有较高的风湿性瓣膜病、镰状细胞病病史,尿酸水平较高,血红蛋白水平较低。SC患者高血压、糖尿病和吸烟史较高。两组的甲状腺疾病发生率相等。结论房颤患病率为3.4%,男性居多,占65%。亚大陆血统的患者更年轻,有高血压和缺血性心脏病的高病史。中东裔患者患风湿性心脏病和镰状细胞病的比例明显较高。高血压史是房颤患者不良事件最重要的独立临床预测因子。
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引用次数: 7
Pulsed and Tissue Doppler Echocardiographic Changes in Hypertensive Crisis with and without End Organ Damage 伴有和不伴有终末器官损害的高血压危象的脉冲和组织多普勒超声心动图变化
Pub Date : 2011-01-01 DOI: 10.4137/OJCS.S8094
Taysir Garadah, S. Kassab, Saleh Gabani, Ahmed A. Abu-Taleb, Ahmed Abdelatif, A. Asef, Issa Shoroqi, A. Jamsheer
Background Hypertensive crisis (HC) is a common medical emergency associated with acute rise in arterial blood pressure that leads to end-organ damage (EOD). Therefore, it is imperative to find markers that may help in the prediction of EOD in acute hypertensive crisis. Aim To assess the clinical presentations on admission; echocardiographic changes of pulsed and tissue Doppler changes in EOD patients compared with no EOD; and the risk of developing end organ damage for clinical and biochemical variables in hypertension crisis. Material and Methods The data of 241 patients with hypertensive crisis with systolic blood pressure (SBP) of >180 mmHg or diastolic blood pressure (DBP) >120 mmHg were extracted from patients files. Patients divided into hypertensive emergency (HE) with EOD, n = 62 and hypertensive urgency (HU) without EOD, n = 179. LV hypertrophy on ECG, echo parameters for wall thickness, left Ventricular mass index (LVMI), Body mass index (BMI), pulse Doppler ratio of early filling velocity E wave to late A wave (E/A) and ratio of E wave velocity to tissue Doppler Em to E wave (E/Em) were evaluated. Serum creatinine, hemoglobin, age, gender, body mass Index (BMI), history of diabetes mellitus, smoking, hypertension, stroke and hyperlipidemia were recorded. Multiple logistic regression analysis was applied for risk prediction of end organ damage of clinical variables. Results Patients with HE compared with HU were significantly older, with a significantly higher SBP on admission, high BMI and LVMI. Further there were significantly higher E/A ratio on Doppler echo and higher E/Em ratio on tissue Doppler echocardiogram. Multiple regression analysis with adjustment for age and sex shows positive predictive value with odds ratio of SBP on admission >220 mmHg of 1.98, serum creatinine > 120 µg/L of 1.43, older age > 60 year of 1.304, obesity (BMI ≥ 30) of 1.9, male gender of 2.26 and left ventricle hypertrophy on ECG of 1.92. The hemoglobin level, history of smoking, hyperlipidemia and DM were with no significant predictive value. The pulsed Doppler E/A ratio was ≥1.6, E/Em > 15, LVMI > 125 gm/m2 in patients with EOD compared with those without. Conclusion In patients presented with hypertensive crisis, the echo indices of E/A ratio and E/Em ratio of tissue Doppler are significantly higher in patients with hypertensive emergency compared to hypertensive urgency. The left ventricle hypertrophy on ECG, high LV mass index of >125 gm/m2, BMI > 30, old age > 60 year, male gender and history of hypertension and stroke were positive predictors of poor outcome and end organ damage.
背景高血压危象(HC)是一种常见的医学急症,与动脉血压急性升高导致终末器官损伤(EOD)相关。因此,寻找有助于预测急性高血压危重期EOD的标志物势在必行。目的评价住院患者的临床表现;与非EOD患者相比,EOD患者的超声心动图脉冲和组织多普勒变化;高血压危重期临床生化指标发生终末器官损害的风险。材料与方法从患者档案中提取241例收缩压(SBP)为>80 mmHg或舒张压(DBP)为>120 mmHg的高血压危重症患者资料。患者分为合并EOD的高血压急症(HE) 62例和未合并EOD的高血压急症(HU) 179例。评价心电图左室肥厚、壁厚回声参数、左室质量指数(LVMI)、体质量指数(BMI)、早期充盈速度E波与晚期A波的脉冲多普勒比值(E/A)、E波速度与组织多普勒Em /E波比值(E/Em)。记录血清肌酐、血红蛋白、年龄、性别、体质指数(BMI)、糖尿病史、吸烟史、高血压史、脑卒中史、高脂血症史。应用多元logistic回归分析对临床变量终末器官损伤的风险进行预测。结果HE患者年龄明显大于HU患者,入院时收缩压明显增高,BMI和LVMI均较高。多普勒超声心动图E/A比和组织超声心动图E/Em比均显著增高。经年龄、性别校正的多元回归分析显示,入院时收缩压比值比>220 mmHg为1.98,血清肌酐> 120µg/L为1.43,老年> 60岁比值比1.304,肥胖(BMI≥30)1.9,男性2.26,心电图左心室肥厚1.92,具有阳性预测值。血红蛋白水平、吸烟史、高脂血症、糖尿病无显著预测价值。与非EOD患者相比,EOD患者的脉冲多普勒E/A比值≥1.6,E/Em >5, LVMI > 125 gm/m2。结论在出现高血压危象的患者中,高血压急症患者的E/A比和组织多普勒E/Em比的回声指标明显高于高血压急症患者。心电图显示左心室肥厚、左室质量指数b> 125 gm/m2、BMI b> 30、年龄b> 60岁、男性、高血压和脑卒中史是预后不良和终末器官损害的阳性预测因子。
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引用次数: 0
Operative Myocardial Protection in Patients with Left Ventricular Hypertrophy: The Role of Systemic Hypothermia 左心室肥厚患者的手术心肌保护:全身低温的作用
Pub Date : 2011-01-01 DOI: 10.4137/OJCS.S6937
Tamer Elghobary, I. Ali, A. F. Ahmad
Objectives Myocardial hypertrophy represents a great challenge in cardiac surgery. Several strategies have been described to protect the hypertrophied myocardium during cardiopulmonary bypass, and aortic clamping, yet the ideal strategy has not been identified. This study investigates the use of moderate systemic hypothermia (MSH) as an adjuvant method to protect the hypertrophied myocardium in patients undergoing aortic valve replacement (AVR). Methods Twenty eight patients undergoing AVR were divided into two groups, (Group I) received continuous cold 5–8 °C retrograde blood cardioplegia (CRBC) and their body temperature was cooled down to 23–26 °C. (Group II) also received CRBC but their body temperature was kept at 32–34 °C. Results No operative morality (30 days) was noted in both groups. Postoperative reduction in ejection fraction (EF) was seen in nine patients of group I and in twelve patients of group II (P < 0.05). The need for multiple inotropes was more in group II (eight patients) than in group I (two patients) (P < 0.001). IABP was needed in three patients of group II and non in group I (P < 0.01). Conclusion Moderate systemic hypothermia might have a role in protecting hypertrophied myocardium in patients undergoing AVR.
目的心肌肥大是心脏外科的一大难题。在体外循环和主动脉夹紧术中,有几种策略可以保护肥厚的心肌,但理想的策略尚未确定。本研究探讨了在主动脉瓣置换术(AVR)患者中使用中度全身低温(MSH)作为辅助保护肥厚心肌的方法。方法将28例AVR患者分为两组,一组接受5 ~ 8℃持续低温逆行心脏骤停(CRBC),体温降至23 ~ 26℃。(II组)同样接受CRBC,体温保持在32 ~ 34℃。结果两组患者均无手术道德感(30 d)。I组术后射血分数(EF)降低9例,II组术后射血分数(EF)降低12例(P < 0.05)。II组(8例)比I组(2例)更需要多种肌力药物(P < 0.001)。II组有3例患者需要IABP, I组无(P < 0.01)。结论适度全身低温可能对AVR患者肥厚心肌有保护作用。
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引用次数: 1
Simple Techniques to Manage the Patent Internal Mammary Artery in Redo Cardiac Surgery 重做心脏手术中乳腺内动脉未闭的简单处理技术
Pub Date : 2010-01-01 DOI: 10.4137/OJCS.S4507
Ahmed Ahmed, I. Ali, I. Ali, Jacob Cookey
The presence of a patent internal mammary artery (IMA) represents a well-known technical challenge in redo cardiac surgery. Dissection of the IMA and controlling its flow during cardioplegic delivery has thus been considered essential steps. This maneuver however, is associated with the risk of damaging the IMA. Herein, we report a technique, which involves no attempts to dissect, or clamp the IMA in 44 consecutive redo cardiac surgery procedures. The results demonstrate that this technique is simple, safe, and reduces the chance of IMA injury.
乳房内动脉未闭(IMA)是心脏重做手术中一个众所周知的技术挑战。因此,在心脏截瘫分娩过程中,剥离IMA并控制其流量被认为是必不可少的步骤。然而,这种操作有损害IMA的风险。在此,我们报告了一项技术,该技术在44例连续重做心脏手术中不涉及解剖或夹紧IMA。结果表明,该技术简单,安全,并减少了IMA损伤的机会。
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引用次数: 0
Gas Exchange during Lung Perfusion/Ventilation during Cardiopulmonary Bypass: Preliminary Results of a Pilot Study 体外循环期间肺灌注/通气期间的气体交换:一项初步研究的初步结果
Pub Date : 2010-01-01 DOI: 10.4137/OJCS.S4109
F. I. Macedo, Enisa M. Carvalho, E. Gologorsky, M. Barron, Mohammed F Hassan, T. Salerno
Lung perfusion/ventilation was introduced as a means to minimize cardiopulmonary (CPB)-related pulmonary ischemic injury. Current results in the literature are divergent, and the role of gas exchange during lung perfusion/ventilation during CPB, remains undefined. This report details a) the technique of continuous lung perfusion/ventilation during CPB, b) provides initial observations, and c) discusses gas exchange during CPB.
肺灌注/通气是减少心肺(CPB)相关肺缺血性损伤的一种手段。目前的文献结果存在分歧,CPB期间肺灌注/通气过程中气体交换的作用仍未明确。本报告详细介绍了a) CPB期间持续肺灌注/通气技术,b)提供了初步观察结果,c)讨论了CPB期间的气体交换。
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引用次数: 7
Iatrogenic Systemic Venous Return Abnormality 医源性全身静脉回流异常
Pub Date : 2010-01-01 DOI: 10.4137/117906521000300001
O. Tiryakioglu, H. Ari, S. Tiryakioğlu, A. Ozyazicioglu
An iatrogenic systemic venous return abnormality was found in a female patient who had previously undergone surgery to correct a superiorly located atrial septal defect and then had increasing complaints. Here we consider the importance of contrast echocardiography in the diagnosis and discuss the patient's second operation as well as the possible mistakes in the first operation.
医源性全身静脉回流异常被发现在一个女性病人谁曾接受手术纠正心房间隔缺损,然后越来越多的投诉。在此,我们考虑超声造影在诊断中的重要性,并讨论患者的第二次手术以及第一次手术可能出现的错误。
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引用次数: 0
Single Center Experience with Short-term Circulatory Support: A Comparison of Demography, Indication and Clinical Outcome over the past Decade 短期循环支持的单中心经验:过去十年人口统计学、适应证和临床结果的比较
Pub Date : 2010-01-01 DOI: 10.4137/OJCS.S5396
J. Linneweber, P. Swojanowsky, P. Dohmen, H. Grubitzsch, S. Dushe, S. Holinski, W. Konertz
Objective Aim of the study was to analyze changes over a ten years observation period regarding demography, indication for support and clinical outcome in patients treated with short-term mechanical circulatory support (MCS) for cardiogenic failure. Methods 39 patients treated with MCS between 2006–2008 (2008 group) were analyzed, assessing demography, complication rates and survival. Results were compared with 36 consecutive patients that had received centrifugal MCS between 1996–1998 (1998 group) at our institution. Results Mean age was 59.9 ± 12.9 (1998 group) and 60.9 ± 13.9 years (P = 0.74). Mean logEuroScores rose from 12.0% ± 14.6% (1998 group) to 26.9% ± 20.5% (2008 group); P < 0.001. Postcardiotomy low output syndrome was the main cause for MCS. However the percentage of patients in cardiogenic shock prior to surgery increased from 19.4% (1998 group) to 33.3% (2008 group); P = 0.17. Complexity and urgency of the primary surgical procedure increased significantly. 16.7% (1998 group) vs. 41.0% (2008 group); P = 0.02 of interventions were classified “salvage/emergent”. Mean duration of support was 2.9 ± 1.9 days (1998 group) and 3.8 ± 3.1 days (2008 group); P = 0.14. Significantly more biventricular support was implemented in the 2008 group (23.1% vs. 5.6% in the 1998 group); P = 0.03. The incidence of complications, including device failure, thromboembolism and infection remained the same in both groups. 63.9% (1998 group) and 61.5% (2008 group) of the patients were successfully weaned from the device (P = 0.83), 12% (1998 group) and 3% (2008 group) of the VAD patients were bridged to long-term VAD (P = 0.12). Overall 30-day survival rates were similar (22.2% 1998 group vs. 28.2%; 2008 group); P = 0.55, however, survival rate in BVAD supported patients improved significantly. Conclusion These data demonstrate the beneficial effect of MCS to salvage patients with cardiac failure. Taking into consideration that the severity of illness, the complexity and urgency of the primary surgical procedure have steadily increased a comparable improvement in MCS outcome over the past decade was observed. Nevertheless, in-hospital mortality and VAD related complication rates such as bleeding remain high.
目的本研究的目的是分析在10年的观察期内,在接受短期机械循环支持(MCS)治疗的心源性心力衰竭患者的人口学、支持指征和临床结果的变化。方法分析2006-2008年收治的39例MCS患者(2008年组)的人口学特征、并发症发生率及生存率。结果与我院1996-1998年间36例连续接受离心MCS的患者(1998组)进行比较。结果平均年龄为59.9±12.9岁(1998年组)和60.9±13.9岁(P = 0.74)。平均logEuroScores从12.0%±14.6%(1998年组)上升到26.9%±20.5%(2008年组);P < 0.001。心切术后低输出综合征是导致MCS的主要原因。但术前发生心源性休克的比例从1998年组的19.4%上升到2008年组的33.3%;P = 0.17。初级外科手术的复杂性和紧迫性显著增加。16.7%(1998年组)vs 41.0%(2008年组);P = 0.02的干预措施被分类为“救助/紧急”。平均支持时间为2.9±1.9天(1998年组),3.8±3.1天(2008年组);P = 0.14。2008年组实施了更多的双心室支持(23.1% vs. 1998年组5.6%);P = 0.03。并发症的发生率,包括器械失效,血栓栓塞和感染在两组中保持不变。63.9%(1998组)和61.5%(2008组)的患者成功脱离VAD (P = 0.83), 12%(1998组)和3%(2008组)的VAD患者桥接至长期VAD (P = 0.12)。总体30天生存率相似(1998年组22.2% vs. 28.2%;2008组);P = 0.55,但BVAD支持患者的生存率明显提高。结论MCS对心力衰竭患者的抢救效果良好。考虑到疾病的严重程度,初级外科手术的复杂性和紧迫性稳步增加,在过去十年中观察到MCS结果的可比改善。然而,住院死亡率和VAD相关并发症(如出血)仍然很高。
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引用次数: 0
Doty's Method (Two Sinus Reconstructions) of Supravalvular Aortic Stenosis in Williams's Syndrome 多蒂法(双窦重建)治疗威廉姆斯综合征的瓣上主动脉狭窄
Pub Date : 2009-01-01 DOI: 10.4137/OJCS.S3721
O. Tiryakioglu, S. Tiryakioğlu, H. Ari, H. Vural, A. Ozyazicioglu
We experienced a successful surgical Williams's syndrome case of extended aortoplasty by means of Doty's method (two sinus reconstructions) for congenital supravalvular aortic stenosis. Case was 29-year-old woman, who had no complaint except heart murmur and dyspnea. The retrograde aortography and Digital Subtraction Angiography (DSA) demonstrated localized stenosis just above the aortic valve, and it was an hour-glass type. This case showed excellent results. Doty's aortoplasty was favorable method for supravalvular aortic stenosis without deformity of aortic valve and coronary obstruction.
我们经历了一例成功的威廉姆斯综合征手术病例,采用多蒂法(双窦重建)治疗先天性瓣上主动脉狭窄。病例为29岁女性,除心脏杂音和呼吸困难外无其他主诉。逆行主动脉造影和数字减影血管造影(DSA)显示主动脉瓣上方局部狭窄,为沙漏型。这个病例显示了良好的效果。Doty主动脉成形术是治疗瓣上主动脉狭窄、无主动脉瓣畸形和冠状动脉阻塞的良好方法。
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引用次数: 0
期刊
Open journal of cardiovascular surgery
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