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Mitral Valve Replacement-Current and Future Perspectives. 二尖瓣置换术的现状和未来展望。
Pub Date : 2017-07-13 eCollection Date: 2017-01-01 DOI: 10.1177/1179065217719023
Johan van der Merwe, Filip Casselman

The favorable outcomes achieved with modern mitral valve repair techniques redefined the role of mitral valve replacement. Various international databases report a significant decrease in replacement procedures performed compared with repairs, and contemporary guidelines limit the application of surgical mitral valve replacement to pathology in which durable repair is unlikely to be achieved. The progressive paradigm shift toward endoscopic and robotic mitral valve surgery is also paralleled by rapid developments in transcatheter devices, which is progressively expanding from experimental approaches to becoming clinical reality. This article outlines the current role and future perspectives of contemporary surgical mitral valve replacement within the context of mitral valve repair and the dynamic evolution of exciting transcatheter alternatives.

现代二尖瓣修复技术取得的良好效果重新定义了二尖瓣置换术的作用。各种国际数据库报告,与修复手术相比,手术二尖瓣置换术的应用显著减少,当代指南限制了外科二尖瓣置换术的应用,因为在病理上不太可能实现持久的修复。向内窥镜和机器人二尖瓣手术的逐步转变也与经导管设备的快速发展并行,经导管设备正逐步从实验方法扩展到临床现实。本文概述了在二尖瓣修复的背景下,当代外科二尖瓣置换术的作用和未来的前景,以及令人兴奋的经导管替代方案的动态演变。
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引用次数: 27
Driveline Infection in Ventricular Assist Devices and Its Implication in the Present Era of Destination Therapy. 心室辅助装置的传动系统感染及其在当前目的地治疗时代的意义。
Pub Date : 2017-06-22 eCollection Date: 2017-01-01 DOI: 10.1177/1179065217714216
Gabriel A Hernandez, Jonatan D Nunez Breton, Sandra V Chaparro

Advances in mechanical circulatory support devices provided the technology to develop long-term, implantable left ventricular assist devices as bridge to transplant, destination therapy, and in a lesser group of patients, as bridge to recovery. Despite the benefits from this innovative therapy, with their increased use, many complications have been encountered, one of the most common being infections. With the driveline acting as a portal to the exterior environment, an infection involving this structure is the most frequent one. Because patients with destination therapy are expected to receive circulatory support for a longer period of time, we will focus this review on the risk factors, prevention, and treatment options for driveline infections.

机械循环支持装置的进步为开发长期的、可植入的左心室辅助装置提供了技术,作为移植的桥梁,目的治疗,在少数患者中,作为恢复的桥梁。尽管这种创新疗法有好处,但随着使用的增加,也出现了许多并发症,其中最常见的是感染。由于传动系统是通往外部环境的门户,因此涉及该结构的感染是最常见的感染。由于接受目的地治疗的患者预计将接受更长时间的循环支持,因此我们将重点关注传动系统感染的危险因素、预防和治疗方案。
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引用次数: 22
Huge Left Atrial Myxoma and Concomitant Silent Coronary Artery Disease in a Young Man 年轻人巨大左心房黏液瘤伴无症状冠状动脉疾病1例
Pub Date : 2016-01-01 DOI: 10.4137/OJCS.S40085
M. Gennari, M. Rubino, D. Andreini, G. Polvani, M. Agrifoglio
Severe but silent coronary artery disease may rarely exist in young patients with a low-risk profile but with a family history of coronary artery disease. We describe the case of a 33-year-old Caucasian male with progressive shortness of breath caused by a huge left atrial myxoma who was diagnosed to have significant coronary artery disease in the preoperative assessment. After investigations, the patient underwent resection of the left atrial tumor and coronary artery bypass grafting (CABG) with a successful outcome. Even in the case of a young male, it may be prudent to investigate silent coronary artery disease in the presence of cardiovascular risk factors and family history of coronary artery disease. The learning objective of this case is to debate about the usefulness of a preoperative coronary study even in the young population with cardiac nonischemic pathologies (ie, valve pathology, cardiac tumors, etc.).
严重但沉默的冠状动脉疾病可能很少存在于低风险但有冠状动脉疾病家族史的年轻患者中。我们描述的情况下,33岁的高加索男性进行性呼吸短促引起的一个巨大的左心房粘液瘤谁被诊断为有明显的冠状动脉疾病在术前评估。经检查,患者接受了左心房肿瘤切除术和冠状动脉旁路移植术(CABG),结果成功。即使是年轻男性,在存在心血管危险因素和冠状动脉疾病家族史的情况下,调查无症状冠状动脉疾病也是谨慎的。本病例的学习目的是讨论术前冠状动脉检查的有效性,即使在患有心脏非缺血性病变(即瓣膜病变、心脏肿瘤等)的年轻人群中也是如此。
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引用次数: 2
Basilic Vein Transposition Used as a Tertiary Vascular Access for Hemodialysis: 15 Years of Experience 基底静脉转位作为三级血管通路用于血液透析:15年的经验
Pub Date : 2016-01-01 DOI: 10.4137/OJCS.S34837
R. Novotný, M. Slavikova, J. Hlubocký, P. Mitáš, J. Hrubý, J. Lindner
Introduction The quality of the life in patients requiring long term hemodialysis is directly proportional to the long-term patency of their vascular access. Basilic vein transposition for vascular access (BAVA) represents a suitable option for creating a tertiary native vascular access for hemodialysis on the upper extremities for patients requiring long term hemodialysis. The purpose of the study is to compare BAVAs with arteriovenous grafts (AVG). Method Data collection was based on selecting all of the patients with BAVA created in the time period in between January 1996 and August 2011. A questionnaire was created and sent to the selected hemodialysis centers. The resulting set of data was statistically analyzed and evaluated. Results In the time period between 1 January 1996 and August 2011, arteriovenous access for hemodialysis was created in 6754 patients (7203 procedures in total). Out of these patients, 175 BAVAs were created. Our patient database of those undergoing the BAVA procedure consisted of 98 females (56%) and 77 males (44%) with an average age of 64.5 years. The prevalence of diabetes mellitus was 60% (105 patients). Primary patency after 12 months was 68.8%, 24 months 59.7%, 36 months 53.8, 48 months 53.8%, and 60 months 50%. Primary assisted patency after 12 months was 89.9%, 24 months 84.6%, 36 months 77.8%, 48 months 77.9%, 60 months 70.8%. Secondary patency after 12 months was 89.4%, 24 months 86.9%, 36 months 81%, 48 months 78.9%, 60 months 75.7%. Twenty-nine BAVAs (16.5%) were obliterated. Conclusion Patients benefit from this type of procedure due to the longer patency of a native arteriovenous access, as well as a lower incidence of infectious complications.
需要长期血液透析的患者的生活质量与其血管通路的长期通畅成正比。对于需要长期血液透析的上肢患者,Basilic vein transpotionfor vascular access (BAVA)是一种合适的选择,可以为上肢血液透析患者创建三级原生血管通路。该研究的目的是比较BAVAs与动静脉移植物(AVG)。方法选取1996年1月至2011年8月期间发生的所有BAVA患者进行数据收集。制作了一份调查问卷,并将其发送到选定的血液透析中心。对所得数据集进行统计分析和评价。结果1996年1月1日至2011年8月期间,共建立了6754例血液透析动静脉通路(7203例)。在这些患者中,产生了175个baas。我们接受BAVA手术的患者数据库包括98名女性(56%)和77名男性(44%),平均年龄为64.5岁。糖尿病患病率为60%(105例)。术后12个月通畅68.8%,24个月通畅59.7%,36个月通畅53.8%,48个月通畅53.8%,60个月通畅50%。术后12个月辅助通畅率为89.9%,24个月为84.6%,36个月为77.8%,48个月为77.9%,60个月为70.8%。12个月后二次通畅率为89.4%,24个月为86.9%,36个月为81%,48个月为78.9%,60个月为75.7%。29个bava(16.5%)消失。结论:该术式具有较长的动静脉通道通畅性和较低的感染并发症发生率,使患者受益。
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引用次数: 2
Retraction: "Bedside surgery to treat patent ductus arteriosus in low-birth-weight premature infants". 缩回:“床边手术治疗低出生体重早产儿动脉导管未闭”。
Pub Date : 2014-10-01 eCollection Date: 2014-01-01 DOI: 10.4137/OJCS.S20358
The authors retract their article, Albayrak G, Aykut K, Karacelikon M, et al. Bedside Surgery to Treat Patent Ductus Arteriosus in Low-Birth-Weight Premature Infants. Open Journal of Cardiovascular Surgery. 2014;7:1–4. doi:10.4137/OJCS.S16156, on the basis of non-compliance with IRB requirements at their institution. The editor in chief agrees with the need for this retraction. The publisher requires that all submissions to the journal obtain appropriate ethical approvals prior to submission. Confirmation was sought and subsequently obtained from the authors prior to publication, on August 8, 2014, that local ethical approval was not required on the basis that the study reported was retrospective. Following publication, journal staff were informed by the authors on August 25, 2014, that approval was in fact required by their institution, and that it had not been obtained and could not be obtained retrospectively. In compliance with Committee on Publication Ethics guidelines, the article is therefore hereby retracted. We apologize for any inconvenience caused to readers by the publication of this article.
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引用次数: 0
Bedside surgery to treat patent ductus arteriosus in low-birth-weight premature infants. 床边手术治疗低出生体重早产儿动脉导管未闭。
Pub Date : 2014-08-17 eCollection Date: 2014-01-01 DOI: 10.4137/OJCS.S16156
Gökhan Albayrak, Koray Aykut, Mustafa Karacelik, Ramazan Soylar, Kemal Karaarslan, Burçin Abud, Mehmet Guzeloglu, Eyup Hazan

Background: Patent ductus arteriosus (PDA) is commonly seen in premature infants with low birth weights (LBW). It is a condition that has high mortality and morbidity rates. Early closure of the ductus arteriosus may require surgery or medical treatment. However, the decision of first medical approach for symptomatic PDA closure is still debated. In this study, we compared the surgical and medical treatments for the closure of PDA in premature LBW infants.

Methods: This study included 27 premature infants whose birth weights were lower than 1500 g, who were born in the period between 2011 and 2013 and had symptomatic PDA. Patients were separated into two groups: groups A and B. Group A included patients whose PDAs were closed with medical treatment (n = 16), and group B included patients who had undergone surgical operations for PDA closure (n = 11).

Results: There were no statistically significant differences between groups A and B when the groups were compared in terms of birth weight, gestational age, respiratory distress syndrome (RDS), necrotizing enterocolitis (NEC), sepsis, intraventricular hemorrhage (IVH), retinopathy of prematurity (ROP), and pneumothorax. Although the mortality rate was determined to be lower in group B (2 out of 11, 18.1%) than in group A (7 out of 16, 43.7%), no statistically significant difference was found between the two groups. A statistically significant increase was determined in the incidence of kidney function loss in patient group that received Ibuprofen, a medical treatment, in comparison to the patients who had surgery.

Conclusion: In conclusion, surgery is a safe method to repair PDA in premature LBW infants. Although there is no remarkable difference between surgery and medical treatment, we suggest that a surgical approach may be used as a first choice to repair PDA considering the lower rate of mortality and morbidity and higher rate of closure compared to medical treatment.

背景:动脉导管未闭常见于低出生体重早产儿(LBW)。这是一种死亡率和发病率都很高的疾病。动脉导管过早闭合可能需要手术或药物治疗。然而,对于有症状的PDA关闭的第一医疗途径的决定仍然存在争议。在本研究中,我们比较了手术和药物治疗关闭早产儿LBW PDA的方法。方法:选取2011 ~ 2013年出生、有症状性PDA的27例出生体重低于1500 g的早产儿为研究对象。将患者分为两组:A组和B组。A组为经药物治疗闭合PDA的患者(n = 16), B组为经手术闭合PDA的患者(n = 11)。结果:A组与B组在出生体重、胎龄、呼吸窘迫综合征(RDS)、坏死性小肠结肠炎(NEC)、败血症、脑室内出血(IVH)、早产儿视网膜病变(ROP)、气胸等方面比较,差异均无统计学意义。虽然确定B组的死亡率(11人中有2人,18.1%)低于A组(16人中有7人,43.7%),但两组之间没有统计学上的显著差异。与接受手术的患者相比,接受布洛芬(一种药物治疗)的患者组肾功能丧失的发生率在统计学上有显著增加。结论:手术是一种安全的方法修复早产儿LBW的PDA。虽然手术和药物治疗之间没有显著差异,但考虑到与药物治疗相比,手术治疗的死亡率和发病率较低,闭合率较高,我们建议将手术方法作为修复PDA的首选方法。
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引用次数: 4
Heart surgery in end-stage renal disease: is outcome worse for african american patients? 心脏手术治疗终末期肾病:非裔美国患者的预后更差吗?
Pub Date : 2013-08-11 eCollection Date: 2013-01-01 DOI: 10.4137/OJCS.S11395
Jonathan O Nwiloh, Chamberlain I Obialo

General results of open heart surgery in end-stage renal disease patients (ESRD) have been well-documented. However, it is unknown if the African American subgroup with known decreased access to advanced healthcare services and a higher prevalence rate of ESRD have a worse long-term survival after heart surgery. Thirty of 150 African American patients who underwent open heart surgery by a single surgeon at an urban community hospital between 1996 and 2010 were identified to have ESRD and were on chronic maintenance hemodialysis prior to surgery. Clinical and outcome data from both groups were retrospectively analyzed. There were no significant differences in the baseline demographic characteristics of the patients, but the ESRD cohort showed a significantly higher prevalence of peripheral vascular and cardiovascular diseases [P < 0.001]. Compared to the non-ESRD subjects, the predicted logistic EuroSCORE was 16.4% vs. 9.4%, [P < 0.001], while the observed 30 days operative mortality was 16.6% vs. 4.2% [P < 0.02], respectively. In isolated coronary artery bypass graft cases, operative mortality was 20.8% and 3.0%, respectively. The 5- and 10-year post-surgery survival was 40% and 25% vs. 72% and 57% [P < 0.01], respectively, in the ESRD and non-ESRD groups. Operative mortality and survival was worse in ESRD patients compared to non-ESRD patients based on their preoperative risk scores. Although the operative mortality of our ESRD patients was high, long-term survival was comparable to reports from both the United States Renal Data System and a Japanese ESRD cohort.

终末期肾病患者(ESRD)的心脏直视手术的一般结果已经得到了充分的证明。然而,目前尚不清楚非裔美国人亚组是否有较差的心脏手术后长期生存率,他们获得先进医疗服务的机会较少,ESRD患病率较高。1996年至2010年间,150名非裔美国患者在一家城市社区医院接受了由一名外科医生进行的心脏直视手术,其中30人被确定患有ESRD,并在手术前进行了慢性维持性血液透析。回顾性分析两组的临床和结局资料。患者的基线人口学特征没有显著差异,但ESRD队列显示外周血管和心血管疾病的患病率明显更高[P < 0.001]。与非esrd组相比,预测logistic EuroSCORE为16.4%比9.4%,[P < 0.001],观察到的30天手术死亡率分别为16.6%比4.2% [P < 0.02]。孤立冠状动脉旁路移植术的手术死亡率分别为20.8%和3.0%。ESRD组和非ESRD组术后5年和10年生存率分别为40%和25%,分别为72%和57% [P < 0.01]。基于术前风险评分,ESRD患者的手术死亡率和生存率比非ESRD患者更差。虽然我们的ESRD患者的手术死亡率很高,但长期生存率与美国肾脏数据系统和日本ESRD队列的报告相当。
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引用次数: 2
Deep sternal wound complications: an overview of old and new therapeutic options. 深胸骨伤口并发症:新旧治疗方案综述。
Pub Date : 2013-06-13 eCollection Date: 2013-01-01 DOI: 10.4137/OJCS.S11199
Leopold Rupprecht, Christof Schmid

Deep sternal wound complications represent a significant problem in current open heart surgery and still pose a tremendous challenge to surgeons. Over the years, many treatment modalities have been proposed, but only few found their way into daily clinical practice of cardiothoracic surgeons. A gold standard has not been defined yet. This review was designed to give an overview of the preferred surgical strategies.

胸骨深伤并发症是目前心内直视手术中的一个重要问题,对外科医生仍然是一个巨大的挑战。多年来,已经提出了许多治疗方法,但只有很少的方法能进入心胸外科医生的日常临床实践。金本位还没有被定义。本综述旨在概述首选的手术策略。
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引用次数: 27
Ruptured thoracic aortic aneurysm infected with listeria monocytogenes: a case report and a review of literature. 感染李斯特菌的胸主动脉瘤破裂:病例报告和文献综述。
Pub Date : 2013-04-29 eCollection Date: 2013-01-01 DOI: 10.4137/OJCS.S11446
Shigeki Masuda, Nobuhiro Takeuchi, Masanori Takada, Koichi Fujita, Yoshiharu Nishibori, Takao Maruyama

A 75-year-old male with a history of alcoholic liver cirrhosis, sigmoid colon cancer, and metastatic liver cancer was admitted to our institution with a complaint of a prickly feeling in his chest. On admission, a chest radiograph revealed a normal cardio-thoracic ratio of 47%. Echocardiography revealed pericardial effusion and blood chemical analyses revealed elevated C-reactive protein levels (14.7 mg/dL). On day 3, chest radiography revealed cardiomegaly with a cardio-thoracic ratio of 58% and protrusion of the left first arch. Contrast-enhanced chest computed tomography revealed a saccular aneurysm in the aortic arch with surrounding hematoma; thus, a ruptured thoracic aortic aneurysm was suspected. Emergency surgery was performed, which revealed a ruptured aortic aneurysm with extensive local inflammation. The diagnosis of an infected aortic rupture was therefore confirmed. The aneurysm and abscess were resected, followed by prosthetic graft replacement and omental packing. Histopathology of the resected aneurysm revealed gram-positive bacilli; and Listeria monocytogenes was confirmed as the causative organism by culture. Postoperative course was uneventful; on postoperative day 60, the patient was ambulatory and was discharged. Here we report the case of a male with a ruptured thoracic aortic aneurysm infected with L. monocytogenes.

本院收治了一名 75 岁的男性患者,他曾患有酒精性肝硬化、乙状结肠癌和转移性肝癌,主诉胸部有刺痛感。入院时,胸片显示心胸比例正常,为 47%。超声心动图显示心包积液,血液化学分析显示 C 反应蛋白水平升高(14.7 mg/dL)。第 3 天,胸片检查发现心脏肿大,心胸比例为 58%,左第一弓突出。对比增强胸部计算机断层扫描显示,主动脉弓上有一个囊状动脉瘤,周围有血肿;因此,怀疑是胸主动脉瘤破裂。急诊手术显示主动脉瘤破裂,并伴有广泛的局部炎症。因此,主动脉破裂感染的诊断得到了证实。手术切除了动脉瘤和脓肿,随后更换了假体移植物并进行了网膜填塞。切除动脉瘤的组织病理学检查发现了革兰氏阳性杆菌,经培养证实李斯特菌是致病菌。术后病程顺利,术后第 60 天,患者可以行走并出院。在此,我们报告了一例男性胸主动脉瘤破裂患者感染单核细胞增多性李斯特菌的病例。
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引用次数: 0
Dobutamine Stress Echocardiography for the Bedside Assessment of Viability Following a Motor Vehicle Accident and Subsequent Myocardial Infarction: A Case Report. 多巴酚丁胺应激超声心动图用于床旁评估车祸后心肌梗死的存活率:病例报告。
Pub Date : 2012-04-18 eCollection Date: 2012-01-01 DOI: 10.4137/OJCS.S8319
Evan L Brittain, Waleed N Irani, Rashid M Ahmad, Ken Monahan

The authors describe a case of a critically ill patient presenting after motor vehicle trauma complicated by anterior myocardial infarction and cardiogenic shock. Assessment of myocardial viability in the territory of a critically stenosed left anterior descending artery (LAD) was necessary to determine the optimal management strategy. Bedside dobutamine stress echocardiography (DSE) demonstrated viability in the LAD territory and the patient underwent uncomplicated single-vessel bypass surgery with subsequent improvement in left-ventricular function. This case illustrates the utility of bedside DSE to assess myocardial viability in patients for whom other non-invasive modalities are not feasible.

作者描述了一例因机动车外伤并发前心肌梗死和心源性休克的重症患者。为了确定最佳治疗策略,有必要评估左前降支动脉(LAD)严重狭窄区域的心肌存活能力。床旁多巴酚丁胺应激超声心动图(DSE)显示 LAD 区域的心肌有活力,患者接受了简单的单血管搭桥手术,左心室功能随后得到改善。该病例说明了床旁 DSE 在评估心肌存活能力方面的实用性,对于无法采用其他非侵入性方法的患者而言,床旁 DSE 是可行的。
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引用次数: 0
期刊
Open journal of cardiovascular surgery
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