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Incidence and outcomes of neonatal group B streptococcal sepsis in Qatar-a multicentre study. 卡塔尔新生儿B组链球菌败血症的发病率和结局——一项多中心研究
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-17 DOI: 10.1186/s12887-025-05398-x
Sajid Salim Thyvilayil, Anvar Paraparambil Vellamgot, Khalil Salameh, Sudheer Babu Kurunthattilthazhe, Abdurahiman Elikkottil, Liliana Llerena Dominguez, Dhanya Banarjee

Background: Group B Streptococcus (GBS) is the most common cause of neonatal early onset sepsis in term infants and a major cause of late onset sepsis in both term and preterm infants.

Aim: To estimate the incidence of GBSS among neonates born in Qatar between July 2015 and June 2020 (5 years). A secondary aim was to describe the outcomes of the affected babies.

Materials and methods: A retrospective chart review of all neonates born during the study period was performed with the help of medical records departments of the four main maternity hospitals in Qatar, where > 90% of the births occurred.

Results: From 123,878 live births, 113 babies grew GBS in blood culture, during the first 90 days. 72 cases of early-onset GBS sepsis (EOGBSS) and 41 cases of late-onset GBS sepsis (LOGBSS) were identified. The estimated incidence of EOGBSS and LOGBSS were 0.58/1000 live births (95% CI 0.46- 0.73) and 0.33/1000 live births (95% CI 0.24- 0.45) respectively. The overall mortality was 7%, and the chart review identified severe neurodisability among at least 11% of survivors.

Conclusion: The incidences of EOGBSS and LOGBSS in Qatar are 0.58/1000 live births (LB) and 0.33/1000 LB, respectively. The relatively high incidence of EOGBSS probably reflects the high rate of carrier state among pregnant mothers. We did not observe any significant change in incidence after introducing the universal maternal screening for GBS. The overall mortality was similar to previously published data. Further prospective studies are recommended.

背景:B群链球菌(GBS)是足月婴儿新生儿早发型脓毒症的最常见原因,也是足月和早产儿迟发性脓毒症的主要原因。目的:估计2015年7月至2020年6月(5年)在卡塔尔出生的新生儿中GBSS的发病率。第二个目的是描述受影响婴儿的结果。材料和方法:在卡塔尔四家主要妇产医院的医疗记录部门的帮助下,对研究期间出生的所有新生儿进行回顾性图表审查,其中bbb90 %发生在这些医院。结果:在123,878例活产婴儿中,113例婴儿在前90天的血培养中生长GBS。早发性GBS脓毒症(EOGBSS) 72例,晚发性GBS脓毒症(LOGBSS) 41例。EOGBSS和LOGBSS的估计发生率分别为0.58/1000活产(95% CI 0.46- 0.73)和0.33/1000活产(95% CI 0.24- 0.45)。总体死亡率为7%,图表回顾发现至少11%的幸存者存在严重的神经功能障碍。结论:卡塔尔EOGBSS和LOGBSS的发病率分别为0.58/1000活产(LB)和0.33/1000 LB。EOGBSS发病率较高,可能反映了孕妇携带率较高。我们没有观察到在引入普遍的母体筛查GBS后发病率有任何显著变化。总体死亡率与之前公布的数据相似。建议进行进一步的前瞻性研究。
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引用次数: 0
The effects of active play interventions on children's fundamental movement skills: a systematic review. 积极游戏干预对儿童基本运动技能的影响:系统回顾。
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-17 DOI: 10.1186/s12887-024-05385-8
Xinmiao Zhang, Changhao Tang, Miao Geng, Kai Li, Cong Liu, Yujun Cai

Background: Many countries worldwide face the problem of underdeveloped fundamental movement skills (FMS) in children. Active play (AP) holds significant potential for enhancing children's FMS based on its free-choice and unstructured nature, as well as its ease of implementation and dissemination. Therefore, the primary objective of this systematic review was to determine the effects of AP interventions on FMS in typically developing children.

Methods: A systematic literature search was conducted in six electronic databases, Web of Science, PubMed, Embase, Scopus, China National Knowledge Infrastructure (CNKI), and Wan Fang Data, from database inception to May 30, 2024. The main inclusion criteria for literature screening included the intervention modality being AP, the outcome indicator as FMS, and the intervention being for typically developing children. Information on countries and regions, study types, experimental designs, sample characteristics, measurement methods, and intervention effects of the included literature were extracted for the included literature. To assess the risk of bias in the literature, the RoB2.0 tool was used for RCTs, while the ROBINS-I 2.0 tool was applied to non-RCTs.

Result: Of the 3,672 articles retrieved, 9 studies were ultimately included in this review. The risk of bias assessment identified 3 studies as having a low risk of bias and 6 as having a moderate risk. The AP interventions in these 9 studies exhibited varying characteristics, with individual intervention durations ranging from 45 to 60 min, intervention frequencies ranging from once a week to four times per week, and intervention periods spanning from 4 weeks to 6 months. FMS were assessed using the Test of Gross Motor Development-2 (TGMD-2), the Bruininks-Oseretsky Test of Motor Proficiency (BOTMP), the Peabody Development Motor Scales-2 (PDMS-2), and the Movement Assessment Battery for Children (MABC). Regarding the effects of AP interventions on children's FMS, seven studies reported a significant effect, while two others reported no significant effect.

Conclusion: Although the results of the included studies are inconsistent, AP interventions generally demonstrate a positive effect on FMS in typically developing children. To better understand the potential of AP in developing FMS in children, high-quality AP interventions and more in-depth studies across diverse populations, settings, and timeframes are needed. Additionally, greater clarity is needed regarding the components of AP interventions and their quantitative relationships with FMS efficacy.

背景:世界上许多国家都面临着儿童基本运动技能(FMS)不发达的问题。主动游戏(AP)由于其自由选择和非结构化的性质,以及易于实施和传播,在提高儿童FMS方面具有重要的潜力。因此,本系统综述的主要目的是确定AP干预对典型发育儿童FMS的影响。方法:系统检索Web of Science、PubMed、Embase、Scopus、中国知网(CNKI)、万方数据6个电子数据库自建库至2024年5月30日的文献。文献筛选的主要纳入标准为干预方式为AP,结局指标为FMS,干预对象为典型发育儿童。提取纳入文献的国家和地区、研究类型、实验设计、样本特征、测量方法、干预效果等信息。为了评估文献偏倚风险,rct采用RoB2.0工具,非rct采用ROBINS-I 2.0工具。结果:在检索到的3,672篇文章中,9篇研究最终被纳入本综述。偏倚风险评估确定3项研究具有低偏倚风险,6项研究具有中等偏倚风险。这9项研究的AP干预表现出不同的特点,个体干预时间从45 - 60分钟不等,干预频率从每周一次到每周一次不等,干预时间从4周到6个月不等。FMS采用大肌肉运动发展测验-2 (TGMD-2)、Bruininks-Oseretsky运动能力测验(BOTMP)、Peabody运动发展量表-2 (PDMS-2)和儿童运动评估量表(MABC)进行评估。关于AP干预对儿童FMS的影响,7项研究报告有显著影响,2项研究报告无显著影响。结论:虽然纳入的研究结果不一致,但AP干预通常对典型发育儿童的FMS有积极作用。为了更好地了解AP在发展儿童FMS方面的潜力,需要高质量的AP干预措施和在不同人群、环境和时间框架内进行更深入的研究。此外,需要更加明确AP干预措施的组成部分及其与FMS疗效的定量关系。
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引用次数: 0
A quality improvement initiative to improve growth monitoring of children attending immunization clinic in an urban primary health centre in Delhi. 一项质量改进倡议,旨在改善对在德里城市初级保健中心免疫诊所就诊的儿童的生长监测。
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-17 DOI: 10.1186/s12887-024-05373-y
Ravneet Kaur, Udita Singh, K Srinath, Anjusha Ranjith, Baridalyne Nongkynrih

Background: Immunization clinics present an opportunity for passive screening for malnutrition among young children through plotting of growth charts. Passive screening for malnutrition can enable timely interventions and improve morbidity and mortality of under-five children. Therefore, we aimed to increase the plotting of growth charts (weight-for-age) to 90%, among under-five children attending immunization clinics in an Urban Health Centre (UHC) in south Delhi over three months.

Methodology: A Quality Improvement (QI) initiative was undertaken in the immunization clinic of an urban primary health centre in southern Delhi, from January to March 2024. A multi-faceted QI team was formed. The baseline coverage of weight-for-age growth chart plotting in the immunization clinic was 31%. The process flow was mapped, and critical gaps identified by root cause analysis (Fish Bone technique). Change ideas were discussed and prioritized using a prioritization matrix to implement these through sequential PDSA cycles. The main change ideas implemented were training of health workers, allotting regular supervisors for the session, and appending a stamp for quick identification of underweight children. Run chart was used to assess the changes over time. We considered the outcome achieved if the plotting coverage was more than 90% sustained for at least six consecutive immunization sessions.

Results: Multiple change ideas were implemented over a period of three months. The coverage of growth chart plotting increased to more than 90%. Lack of motivation among stakeholders was a challenge for some change ideas. Monitoring of immunization sessions for plotting of growth chart was continued post the implementation of all change ideas to assess sustainability which showed positive results. Post-implementation of the change ideas, a meeting was held with the members of the QI team to get feedback on this activity.

Conclusion: There is potential for improving growth monitoring at immunization clinics, which can be beneficial in strengthening passive screening for malnutrition in primary care settings.

Clinical trial number: Not applicable.

背景:免疫诊所提供了一个通过绘制生长图表被动筛查幼儿营养不良的机会。营养不良被动筛查可使干预措施及时实施,并改善五岁以下儿童的发病率和死亡率。因此,我们的目标是在德里南部一个城市卫生中心(UHC)的免疫诊所就诊的5岁以下儿童中,在三个月内将生长图(年龄体重)绘制率提高到90%。方法:2024年1月至3月,在德里南部一个城市初级保健中心的免疫诊所开展了一项质量改进倡议。组建了一个多方面的QI团队。免疫门诊体重年龄增长图的基线覆盖率为31%。绘制了工艺流程,并通过根本原因分析(鱼骨技术)确定了关键差距。讨论了变更想法,并使用优先级矩阵对其进行优先级排序,通过顺序的PDSA循环实现这些想法。实施的主要改革想法是培训卫生工作者,为会议分配定期监督员,并附加快速识别体重不足儿童的印章。使用运行图来评估随时间的变化。我们认为,如果规划覆盖率在至少连续六次免疫接种中持续超过90%,则实现了结果。结果:在三个月的时间里实施了多个改变想法。增长图绘制覆盖率提高到90%以上。利益相关者缺乏动力是一些变革理念面临的挑战。在实施所有变革理念以评估可持续性并取得积极成果后,继续监测免疫接种期以绘制生长图。变更想法实施后,与QI团队成员召开了一次会议,以获得对该活动的反馈。结论:免疫诊所有可能改善生长监测,这有助于加强初级保健机构营养不良的被动筛查。临床试验号:不适用。
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引用次数: 0
Impact of pediatric COVID-19 isolation on children's well-being and caregiver mental health. 儿童COVID-19隔离对儿童福祉和照顾者心理健康的影响。
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-17 DOI: 10.1186/s12887-025-05399-w
Song I Yang, Chi-Hyun Choi, Eun Joo Lee, Sun Hee Jee, Mi Seon Han

Background: The Korean government implemented mandatory hospital isolation in the early phase of the COVID-19 pandemic. This study investigated the mental health of children and caregivers who underwent mandatory hospital isolation due to COVID-19.

Methods: This prospective study examined the physical condition and mental health of children under 7 years of age with COVID-19 and the mental health of their caregivers who underwent isolation in negative pressure rooms at two hospitals in Korea from April to September 2021. Caregivers received a self-report questionnaire via text message. Their responses were analyzed to compare the physical condition and mental health of children with COVID-19 and the mental health of their caregivers during and after isolation and identify factors influencing caregivers' mental health.

Results: Sixty caregivers participated in the study. More than half of the caregivers perceived their children's disease severity as mild. During hospital isolation, 36.4% of the children experienced decreased oral intake, which improved significantly post-isolation (8.7%, P = 0.014). During isolation, approximately 22.2% of the children frequently awoke from sleep, 20.0% displayed irritability, and 70.8% had symptoms of depression. Approximately 36.7% of caregivers showed at least moderate levels of depression during isolation, which significantly decreased to 14.3% three months after discharge (P = 0.032). Factors associated with caregivers' mental health included child-related issues, such as difficulty concentrating, frequent awakenings, and irritability.

Conclusion: Mandatory hospital isolation has a significantly negative psychological impact on children and caregivers during pandemics. Isolation decisions must be carefully considered during pandemics, especially those concerning young children. Heightened vigilance is warranted for the early detection and intervention of mental health issues in children and their caregivers.

背景:韩国政府在新冠肺炎疫情初期实施了强制医院隔离。本研究调查了因COVID-19而接受强制住院隔离的儿童和护理人员的心理健康状况。方法:本前瞻性研究调查了2021年4月至9月在韩国两家医院负压室隔离的7岁以下COVID-19儿童及其护理人员的身体状况和心理健康状况。护理人员通过短信收到了一份自我报告问卷。分析他们的反应,比较COVID-19儿童及其照顾者在隔离期间和隔离后的身体状况和心理健康状况,并确定影响照顾者心理健康的因素。结果:60名护理人员参与了本研究。超过一半的照顾者认为他们孩子的疾病严重程度是轻微的。在医院隔离期间,36.4%的儿童口腔摄入量减少,隔离后明显改善(8.7%,P = 0.014)。在隔离期间,约22.2%的儿童经常从睡眠中醒来,20.0%表现出烦躁,70.8%有抑郁症状。大约36.7%的护理人员在隔离期间表现出至少中等程度的抑郁,出院3个月后显著下降至14.3% (P = 0.032)。与照顾者心理健康相关的因素包括与儿童有关的问题,如难以集中注意力、频繁醒来和易怒。结论:大流行期间强制医院隔离对儿童和护理人员有显著的负面心理影响。在大流行期间,必须仔细考虑隔离决定,特别是涉及幼儿的隔离决定。必须提高警惕,及早发现和干预儿童及其照料者的心理健康问题。
{"title":"Impact of pediatric COVID-19 isolation on children's well-being and caregiver mental health.","authors":"Song I Yang, Chi-Hyun Choi, Eun Joo Lee, Sun Hee Jee, Mi Seon Han","doi":"10.1186/s12887-025-05399-w","DOIUrl":"10.1186/s12887-025-05399-w","url":null,"abstract":"<p><strong>Background: </strong>The Korean government implemented mandatory hospital isolation in the early phase of the COVID-19 pandemic. This study investigated the mental health of children and caregivers who underwent mandatory hospital isolation due to COVID-19.</p><p><strong>Methods: </strong>This prospective study examined the physical condition and mental health of children under 7 years of age with COVID-19 and the mental health of their caregivers who underwent isolation in negative pressure rooms at two hospitals in Korea from April to September 2021. Caregivers received a self-report questionnaire via text message. Their responses were analyzed to compare the physical condition and mental health of children with COVID-19 and the mental health of their caregivers during and after isolation and identify factors influencing caregivers' mental health.</p><p><strong>Results: </strong>Sixty caregivers participated in the study. More than half of the caregivers perceived their children's disease severity as mild. During hospital isolation, 36.4% of the children experienced decreased oral intake, which improved significantly post-isolation (8.7%, P = 0.014). During isolation, approximately 22.2% of the children frequently awoke from sleep, 20.0% displayed irritability, and 70.8% had symptoms of depression. Approximately 36.7% of caregivers showed at least moderate levels of depression during isolation, which significantly decreased to 14.3% three months after discharge (P = 0.032). Factors associated with caregivers' mental health included child-related issues, such as difficulty concentrating, frequent awakenings, and irritability.</p><p><strong>Conclusion: </strong>Mandatory hospital isolation has a significantly negative psychological impact on children and caregivers during pandemics. Isolation decisions must be carefully considered during pandemics, especially those concerning young children. Heightened vigilance is warranted for the early detection and intervention of mental health issues in children and their caregivers.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"37"},"PeriodicalIF":2.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Idiopathic multicentric Castleman disease in children: a single-center retrospective analysis. 儿童特发性多中心Castleman病:单中心回顾性分析
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-17 DOI: 10.1186/s12887-024-05347-0
Junye Du, Jiafeng Yao, Honghao Ma, Li Li, Ang Wei, Liping Zhang, Dong Wang, Zhigang Li, Rui Zhang, Tianyou Wang

Objective: To investigate the clinical features, pathological phenotype, treatment and prognosis of idiopathic multicenter Castleman disease (iMCD)in children.

Methods: From January 2017 to September 2023, basic information, laboratory tests, treatment and prognosis of children diagnosed with iMCD who attended Beijing Children's Hospital of Capital Medical University were collected.

Results: A total of 9 children were enrolled, with a median age of onset of median 11 (2-15) years, 6 males and 3 female. 3 cases were pathologically typed as plasma cell type, 1 case was mixed type, and the remaining 5 cases were hyaline vascular type. 9 children received different regimens of chemotherapy. The median follow-up time was 26 (13, 58) months, with no deaths, 7/9 cases showing improvement, 1/9 cases showing stable condition, and 1/9 cases showing active condition.

Conclusion: Children with multicentric CD often have systemic symptoms, lymph node enlargement and related compression symptoms are the most common manifestations, followed by fever, malaise and other systemic symptoms. Anti-IL-6-based therapy combined with hormones lenalidomide and other medications have a specific therapeutic effect on multicentric CD.

目的:探讨儿童特发性多中心Castleman病(iMCD)的临床特点、病理表型、治疗及预后。方法:收集2017年1月至2023年9月在首都医科大学附属北京儿童医院就诊的诊断为iMCD患儿的基本信息、实验室检查、治疗及预后。结果:共有9名儿童入组,中位发病年龄为11(2-15)岁,其中6名男性,3名女性。病理分型为浆细胞型3例,混合型1例,透明血管型5例。9名儿童接受了不同的化疗方案。中位随访时间26(13.58)个月,无死亡病例,7/9好转,1/9病情稳定,1/9病情活跃。结论:多中心性CD患儿多有全身性症状,淋巴结肿大及相关压迫症状是最常见的表现,其次为发热、不适等全身性症状。以抗il -6为基础的治疗联合激素来那度胺等药物对多中心性CD有特异性治疗效果。
{"title":"Idiopathic multicentric Castleman disease in children: a single-center retrospective analysis.","authors":"Junye Du, Jiafeng Yao, Honghao Ma, Li Li, Ang Wei, Liping Zhang, Dong Wang, Zhigang Li, Rui Zhang, Tianyou Wang","doi":"10.1186/s12887-024-05347-0","DOIUrl":"https://doi.org/10.1186/s12887-024-05347-0","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinical features, pathological phenotype, treatment and prognosis of idiopathic multicenter Castleman disease (iMCD)in children.</p><p><strong>Methods: </strong>From January 2017 to September 2023, basic information, laboratory tests, treatment and prognosis of children diagnosed with iMCD who attended Beijing Children's Hospital of Capital Medical University were collected.</p><p><strong>Results: </strong>A total of 9 children were enrolled, with a median age of onset of median 11 (2-15) years, 6 males and 3 female. 3 cases were pathologically typed as plasma cell type, 1 case was mixed type, and the remaining 5 cases were hyaline vascular type. 9 children received different regimens of chemotherapy. The median follow-up time was 26 (13, 58) months, with no deaths, 7/9 cases showing improvement, 1/9 cases showing stable condition, and 1/9 cases showing active condition.</p><p><strong>Conclusion: </strong>Children with multicentric CD often have systemic symptoms, lymph node enlargement and related compression symptoms are the most common manifestations, followed by fever, malaise and other systemic symptoms. Anti-IL-6-based therapy combined with hormones lenalidomide and other medications have a specific therapeutic effect on multicentric CD.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"38"},"PeriodicalIF":2.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Burden of undernutrition and its associated factors among children aged 6-59 months: findings from 2016 Ethiopian demographic health survey (EDHS) data. 6-59个月儿童营养不良负担及其相关因素:2016年埃塞俄比亚人口健康调查(EDHS)数据的调查结果
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-16 DOI: 10.1186/s12887-025-05400-6
Wegayehu Enbeyle Sheferaw, Gabriel A Ogunmola, Roy Rillera Marzo, Solomon Abebaw, Assaye Belay, Batholomew Chibuike James, Yesewzer Enawgaw

Background: Despite numerous government nutrition-specific and sensitive interventions, undernutrition (e.g., underweight) remains the major public health concern among under-five-year-old children in Ethiopia. Therefore, this study aimed to assess underweight and associated factors among children in Ethiopia using 2016 EDHS data.

Method: The current study used 9,013 children under five years old. An ordinal logistic regression (e.g., proportional odds model) was applied to determine the associated risk factors of being underweight. The current study used SAS software version 9.4 at the 5% significance level.

Results: The prevalence of underweight was 25.3%. Variables such as children's sex, place of residence, whether the child is twin at birth, breastfeeding status, size of children at birth, childbirth order, employment status of mothers, parents' educational level, children's age groups, the incidence of diarrhea in the past two weeks, and baby fortified food were statistically associated with underweight among under-five age in years.

Conclusions: Underweight among under-five children is predicted by place of residence. In addition, there is a regional disparity of underweight among children. Therefore, further effort is needed to improve health education in children's welfare and health facilities to enhance patients' understanding of proper information and feeding.

背景:尽管政府采取了许多针对营养的敏感干预措施,但营养不足(如体重不足)仍然是埃塞俄比亚五岁以下儿童的主要公共卫生问题。因此,本研究旨在利用2016年EDHS数据评估埃塞俄比亚儿童体重不足及其相关因素。方法:本研究使用了9013名5岁以下的儿童。采用有序逻辑回归(如比例优势模型)来确定体重过轻的相关危险因素。本研究采用SAS软件9.4版本,显著性水平为5%。结果:体重过轻的患病率为25.3%。儿童的性别、居住地、是否为双胞胎、母乳喂养状况、出生时孩子的体型、分娩顺序、母亲的就业状况、父母的受教育程度、儿童的年龄组、过去两周内腹泻的发生率、婴儿强化食品等变量与5岁以下儿童的体重不足有统计学意义。结论:五岁以下儿童体重不足可由居住地预测。此外,儿童体重过轻的情况也存在地区差异。因此,需要进一步努力改善儿童福利和卫生机构的健康教育,以提高患者对正确信息和喂养的理解。
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引用次数: 0
Modified lung ultrasound score for improved monitoring of pARDS on ECMO, a case report. 改良肺超声评分改善ECMO中pARDS的监测1例报告。
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-16 DOI: 10.1186/s12887-024-05308-7
E Küng, L Aichhorn, M Di Nardo, F Cardona, A Berger, R I Milos, M Watzenböck, J B Brandt

Background: Lung ultrasound scoring is a validated tool for assessing lung pathology. However, existing scoring systems typically overlook the size of consolidations, limiting their accuracy in certain clinical scenarios.

Case presentation: We describe the first application of adding the maximum consolidation depth in centimeters (cm) to the conventional score. This modification (LUS+) was used in an eight-month-old patient with severe respiratory failure undergoing extracorporeal life support (ECLS). Spearman's correlation analysis revealed a similar correlation in LUS+ compared to conventional lung ultrasound score. Importantly, LUS + showed improvement following cessation of lung rest on day 5, preceding the changes observed in conventional lung ultrasound scores and tidal volume measurements on day 9.

Conclusions: The integration of consolidation depth, quantified in centimeters, represents a valuable refinement of the conventional lung ultrasound score, enhancing its utility in monitoring pediatric acute respiratory distress patients undergoing ECLS.

背景:肺超声评分是评估肺部病理的有效工具。然而,现有的评分系统通常忽略了合并的大小,限制了它们在某些临床情况下的准确性。案例介绍:我们描述了在常规评分基础上增加厘米(cm)最大固结深度的第一个应用。该改良(LUS+)用于一名接受体外生命支持(ECLS)的8个月大的严重呼吸衰竭患者。Spearman相关分析显示LUS+与常规肺超声评分有相似的相关性。重要的是,LUS +在第5天停止肺休息后有所改善,在第9天观察到常规肺超声评分和潮气量测量的变化之前。结论:整合实变深度,以厘米为单位量化,代表了传统肺超声评分的有价值的改进,增强了其在监测接受ECLS的儿科急性呼吸窘迫患者中的应用。
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引用次数: 0
A qualitative systematic review of umbilical cord care practices in Nigeria. 尼日利亚脐带护理实践的定性系统评价。
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-15 DOI: 10.1186/s12887-025-05387-0
Precious Ebube Anyakorah, Florence Chinelo Aguna, David Chinaecherem Innocent, Anthony Chinonso Uwandu-Uzoma, Uzochukwu Godswill Ekeleme, Chidera Chisom Obasi, Stanley Chinedu Eneh, Chidinma Peace Ahunam, Ihuoma Chimdimma Dike, Vivian Chidimma Maduekwe, Oluwaseunayo Deborah Ayando, Chinazaekpere Oguguo Duruji, Rejoicing Chijindum Innocent, Princess Chidiebube Uwaezuoke, Oluwafunmilayo Opeyemi Adenuga, Chiagoziem Ogazirilem Emerole

Background: Umbilical cord care is an important aspect of newborn health, and different practices exist around the world, often influenced by cultural, healthcare infrastructure, and socioeconomic factors. The objective of this systematic review is to synthesize current literature on umbilical cord care practices in Nigeria, with an emphasis on the impact of cultural beliefs, healthcare infrastructure, and socioeconomic factors.

Methods: A comprehensive search for literature was performed across PubMED, MEDLINE and Google scholar for studies published between 2010 and 2023. The preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines was followed for the execution of this study. Eligibility criteria included only English studies investigating umbilical cord care practices in Nigeria, with outcomes connected to cultural, healthcare, or socioeconomic factors. Critical Appraisal Skills Programme (CASP) checklist was used to critically appraise the quality and rigor of selected studies. Due to the heterogeneity of the studies (qualitative and quantitative), qualitative narrative synthesis was used to synthesize the studies in a textual format for comprehensive understanding.

Results: A total of 11 included studies were found out of 1532 studies. The findings reveal a range of cord care practices, emphasizing the use of various methods such as methylated spirit, hot compresses, and indigenous substances. Cultural beliefs, a lack of healthcare infrastructure, and socioeconomic circumstances all have a big impact on cord care decisions. Disparities in knowledge and adherence to evidence-based procedures are noticeable, particularly in the use of chlorhexidine gel. Infections continue to be a problem, highlighting the significance of appropriate therapies.

Conclusion: This systematic review offers a comprehensive perspective of Nigerian umbilical cord care practices, emphasizing the importance of culturally responsive educational interventions, enhanced healthcare infrastructure, and targeted legislative measures. Despite its limitations, the study is an important resource for guiding future research, policy creation, and interventions to improve maternal and newborn health outcomes in Nigeria.

背景:脐带护理是新生儿健康的一个重要方面,世界各地存在不同的做法,往往受到文化、卫生保健基础设施和社会经济因素的影响。本系统综述的目的是综合目前关于尼日利亚脐带护理实践的文献,重点是文化信仰、医疗基础设施和社会经济因素的影响。方法:综合检索PubMED、MEDLINE和谷歌scholar网站2010 - 2023年间发表的文献。本研究遵循系统评价和荟萃分析(PRISMA)指南的首选报告项目。入选标准仅包括调查尼日利亚脐带护理实践的英语研究,其结果与文化、医疗保健或社会经济因素有关。使用批判性评估技能计划(CASP)检查表对选定研究的质量和严谨性进行批判性评估。由于研究的异质性(定性和定量),我们采用定性叙事综合的方法,以文本形式对研究进行综合,以便全面理解。结果:在1532项研究中,共发现11项纳入研究。研究结果揭示了一系列脐带护理实践,强调使用各种方法,如甲基化酒精、热敷和本土物质。文化信仰、缺乏卫生保健基础设施和社会经济环境都对脐带护理决策产生重大影响。在知识和遵守循证程序方面的差异是显而易见的,特别是在氯己定凝胶的使用方面。感染仍然是一个问题,强调了适当治疗的重要性。结论:本系统综述提供了尼日利亚脐带护理实践的全面视角,强调了文化响应性教育干预、加强医疗基础设施和有针对性立法措施的重要性。尽管有其局限性,但该研究是指导未来研究、制定政策和干预措施以改善尼日利亚孕产妇和新生儿健康结果的重要资源。
{"title":"A qualitative systematic review of umbilical cord care practices in Nigeria.","authors":"Precious Ebube Anyakorah, Florence Chinelo Aguna, David Chinaecherem Innocent, Anthony Chinonso Uwandu-Uzoma, Uzochukwu Godswill Ekeleme, Chidera Chisom Obasi, Stanley Chinedu Eneh, Chidinma Peace Ahunam, Ihuoma Chimdimma Dike, Vivian Chidimma Maduekwe, Oluwaseunayo Deborah Ayando, Chinazaekpere Oguguo Duruji, Rejoicing Chijindum Innocent, Princess Chidiebube Uwaezuoke, Oluwafunmilayo Opeyemi Adenuga, Chiagoziem Ogazirilem Emerole","doi":"10.1186/s12887-025-05387-0","DOIUrl":"10.1186/s12887-025-05387-0","url":null,"abstract":"<p><strong>Background: </strong>Umbilical cord care is an important aspect of newborn health, and different practices exist around the world, often influenced by cultural, healthcare infrastructure, and socioeconomic factors. The objective of this systematic review is to synthesize current literature on umbilical cord care practices in Nigeria, with an emphasis on the impact of cultural beliefs, healthcare infrastructure, and socioeconomic factors.</p><p><strong>Methods: </strong>A comprehensive search for literature was performed across PubMED, MEDLINE and Google scholar for studies published between 2010 and 2023. The preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines was followed for the execution of this study. Eligibility criteria included only English studies investigating umbilical cord care practices in Nigeria, with outcomes connected to cultural, healthcare, or socioeconomic factors. Critical Appraisal Skills Programme (CASP) checklist was used to critically appraise the quality and rigor of selected studies. Due to the heterogeneity of the studies (qualitative and quantitative), qualitative narrative synthesis was used to synthesize the studies in a textual format for comprehensive understanding.</p><p><strong>Results: </strong>A total of 11 included studies were found out of 1532 studies. The findings reveal a range of cord care practices, emphasizing the use of various methods such as methylated spirit, hot compresses, and indigenous substances. Cultural beliefs, a lack of healthcare infrastructure, and socioeconomic circumstances all have a big impact on cord care decisions. Disparities in knowledge and adherence to evidence-based procedures are noticeable, particularly in the use of chlorhexidine gel. Infections continue to be a problem, highlighting the significance of appropriate therapies.</p><p><strong>Conclusion: </strong>This systematic review offers a comprehensive perspective of Nigerian umbilical cord care practices, emphasizing the importance of culturally responsive educational interventions, enhanced healthcare infrastructure, and targeted legislative measures. Despite its limitations, the study is an important resource for guiding future research, policy creation, and interventions to improve maternal and newborn health outcomes in Nigeria.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"34"},"PeriodicalIF":2.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parents' views and experiences of raising babies born with cleft lip and palate: a qualitative study. 父母养育唇腭裂婴儿的观点与经验:一项质性研究。
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-15 DOI: 10.1186/s12887-024-05379-6
Delaram Alinezhad, Farnoosh Mohammadi, Mohammad Javad Kharazifared, Mahdia Gholami, Sarvin Sarmadi, Samaneh Razeghi

Background: Parents of children born with cleft lip/palate encounter numerous challenges. This study aims to provide a deeper understanding for authorities to better support these parents by exploring the views and experiences of Iranian parents raising babies with cleft lip/palate through qualitative research.

Methods: This qualitative study collected data through face-to-face, in-depth, semi-structured interviews. Using purposive sampling, parents of children with cleft lip/palate who visited the Department of Oral and Maxillofacial Surgery at the Children's Medical Center in Tehran, Iran, were selected. Thematic content analysis was employed to interpret the data and identify themes and subthemes.

Results: From 20 interviews, six themes were identified. The diagnosis theme was associated with timing. Key concerns within the psychosocial experiences theme included initial reactions, pressure from society, the child's future in the community, hiding from family, feeling guilty about the anomaly, and couples' relationships. The challenges in childcare theme included feeding difficulties, financial challenges, and cleft treatments. The information acquisition theme included primary awareness and the importance of knowing how to care for the child. The coping theme included gaining awareness, accepting the problem as God's will and destiny, minimizing the significance of the child's cleft, and support. Parents had concerns about informing the child of his/her condition.

Conclusions: Parents of infants with cleft lip/palate feel unsupported by medical staff in feeding practices and seek improved training for staff. They propose a program to empower staff and advocate for psychological support for parents. Access to specialized baby bottles and financial support is crucial, along with establishing a parent-led community for sharing experiences.

背景:唇腭裂患儿的父母面临着许多挑战。本研究旨在通过质性研究探讨伊朗父母养育唇腭裂婴儿的观点和经验,为当局更好地支持这些父母提供更深入的了解。方法:本定性研究通过面对面、深入、半结构化访谈收集数据。采用有目的的抽样方法,选取了在伊朗德黑兰儿童医疗中心口腔颌面外科就诊的唇腭裂儿童的父母。采用主题内容分析来解释数据,识别主题和副主题。结果:从20个访谈中,确定了6个主题。诊断主题与时间有关。心理社会体验主题的主要关注点包括最初的反应、来自社会的压力、孩子在社区中的未来、对家庭的逃避、对异常的内疚以及夫妻关系。儿童保育主题的挑战包括喂养困难、经济困难和唇腭裂治疗。信息获取主题包括基本意识和知道如何照顾儿童的重要性。应对的主题包括提高意识,接受问题是上帝的旨意和命运,尽量减少孩子的唇裂的重要性,以及支持。父母对告知孩子他/她的病情有顾虑。结论:唇腭裂患儿家长在喂养实践中感到医护人员不支持,并寻求对医护人员进行改进培训。他们提出了一项赋予员工权力的计划,并倡导为父母提供心理支持。获得专门的奶瓶和经济支持至关重要,同时建立一个由家长主导的社区来分享经验。
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引用次数: 0
Assessing the impact of mindfulness programs on attention-deficit/ hyperactivity disorder in children and adolescents: a systematic review. 评估正念计划对儿童和青少年注意力缺陷/多动障碍的影响:一项系统综述。
IF 2 3区 医学 Q2 PEDIATRICS Pub Date : 2025-01-14 DOI: 10.1186/s12887-024-05310-z
Meshal A Sultan, Faisal A Nawaz, Batol Alattar, Eman Khalaf, Sidra Shadan, Naila El-Abiary, Shakeel Tegginmani, Rakhtan K Qasba, Jigar Jogia

Background: Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder which poses challenges for the individuals with the disorder and their families. While stimulant medications are effective, a comprehensive approach, including psychosocial and behavioral interventions, is recommended. There is a growing body of research exploring the potential benefits of mindfulness-based interventions for children with ADHD. Our study aims to assess the effectiveness of mindfulness interventions in reducing ADHD symptoms in children and adolescents through a systematic review of relevant studies.

Methods: Following PRISMA guidelines, our systematic review searched PubMed, Cochrane library, Psycinfo, and Scopus from January 2000 to August 2022. We included studies focusing on mindfulness for pediatric ADHD, comprising various study designs with a minimum 8-week duration. Descriptive statistics summarized results, while risk of bias was assessed using Cochrane RoB and ROBANS tools. The quality of RCTs was further evaluated using the Correlation of Quality Measures tool.

Results: In the initial search, 450 records were identified, and after removing duplicates, 339 underwent screening. Forty-one studies underwent full text assessment for eligibility, with 11 studies meeting inclusion criteria, including seven RCTs, two Quasi RCTs, and three cohort studies. These studies, conducted in five countries, involved participants aged 7 to 18 years. Six studies showed improvement in hyperactivity/inattentive symptoms, and five studies showed improvement in impulsivity.

Conclusions: This systematic review demonstrates the potential benefits of mindfulness programs on ADHD symptoms in children and adolescents. This study emphasizes the need for high-quality research to explore mindfulness-based interventions for ADHD management in younger populations. PROSPERO registration number: IDCRD42024520800.

背景:注意缺陷多动障碍(ADHD)是一种常见的神经发育障碍,对患者及其家庭构成了挑战。虽然兴奋剂药物有效,但建议采用综合方法,包括社会心理和行为干预。越来越多的研究在探索以正念为基础的干预对多动症儿童的潜在益处。本研究旨在通过对相关研究的系统回顾,评估正念干预在减少儿童和青少年ADHD症状方面的有效性。方法:根据PRISMA指南,我们的系统综述检索了PubMed、Cochrane图书馆、Psycinfo和Scopus,检索时间为2000年1月至2022年8月。我们纳入了专注于正念治疗小儿多动症的研究,包括各种研究设计,持续时间至少为8周。描述性统计总结了结果,而使用Cochrane RoB和ROBANS工具评估偏倚风险。使用质量测量相关工具进一步评价rct的质量。结果:在最初的搜索中,确定了450条记录,在删除重复记录后,筛选了339条记录。41项研究进行了资格的全文评估,其中11项研究符合纳入标准,包括7项随机对照试验、2项准随机对照试验和3项队列研究。这些研究在五个国家进行,参与者年龄在7到18岁之间。六项研究显示多动症/注意力不集中症状有所改善,五项研究显示冲动性有所改善。结论:本系统综述证明了正念训练对儿童和青少年ADHD症状的潜在益处。本研究强调需要进行高质量的研究,以探索以正念为基础的干预措施在年轻人群中的ADHD管理。普洛斯彼罗注册号:IDCRD42024520800。
{"title":"Assessing the impact of mindfulness programs on attention-deficit/ hyperactivity disorder in children and adolescents: a systematic review.","authors":"Meshal A Sultan, Faisal A Nawaz, Batol Alattar, Eman Khalaf, Sidra Shadan, Naila El-Abiary, Shakeel Tegginmani, Rakhtan K Qasba, Jigar Jogia","doi":"10.1186/s12887-024-05310-z","DOIUrl":"10.1186/s12887-024-05310-z","url":null,"abstract":"<p><strong>Background: </strong>Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder which poses challenges for the individuals with the disorder and their families. While stimulant medications are effective, a comprehensive approach, including psychosocial and behavioral interventions, is recommended. There is a growing body of research exploring the potential benefits of mindfulness-based interventions for children with ADHD. Our study aims to assess the effectiveness of mindfulness interventions in reducing ADHD symptoms in children and adolescents through a systematic review of relevant studies.</p><p><strong>Methods: </strong>Following PRISMA guidelines, our systematic review searched PubMed, Cochrane library, Psycinfo, and Scopus from January 2000 to August 2022. We included studies focusing on mindfulness for pediatric ADHD, comprising various study designs with a minimum 8-week duration. Descriptive statistics summarized results, while risk of bias was assessed using Cochrane RoB and ROBANS tools. The quality of RCTs was further evaluated using the Correlation of Quality Measures tool.</p><p><strong>Results: </strong>In the initial search, 450 records were identified, and after removing duplicates, 339 underwent screening. Forty-one studies underwent full text assessment for eligibility, with 11 studies meeting inclusion criteria, including seven RCTs, two Quasi RCTs, and three cohort studies. These studies, conducted in five countries, involved participants aged 7 to 18 years. Six studies showed improvement in hyperactivity/inattentive symptoms, and five studies showed improvement in impulsivity.</p><p><strong>Conclusions: </strong>This systematic review demonstrates the potential benefits of mindfulness programs on ADHD symptoms in children and adolescents. This study emphasizes the need for high-quality research to explore mindfulness-based interventions for ADHD management in younger populations. PROSPERO registration number: IDCRD42024520800.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"32"},"PeriodicalIF":2.0,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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BMC Pediatrics
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