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Understanding emotional and practical challenges of initiating oxygen therapy in pulmonary fibrosis: insights from a patient-centered survey. 了解在肺纤维化中启动氧疗的情绪和实际挑战：来自以患者为中心的调查的见解。
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-31 DOI: 10.1186/s12890-026-04143-z
Marjolein Drent, Lian Trapman, Miranda Hennevelt-Leenen, Jan C Grutters, Anne-Marie Russell
{"title":"Understanding emotional and practical challenges of initiating oxygen therapy in pulmonary fibrosis: insights from a patient-centered survey.","authors":"Marjolein Drent, Lian Trapman, Miranda Hennevelt-Leenen, Jan C Grutters, Anne-Marie Russell","doi":"10.1186/s12890-026-04143-z","DOIUrl":"https://doi.org/10.1186/s12890-026-04143-z","url":null,"abstract":"","PeriodicalId":9148,"journal":{"name":"BMC Pulmonary Medicine","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isoniazid-induced alopecia in isoniazid-monoresistant pulmonary tuberculosis. 异烟肼单耐药肺结核患者异烟肼致脱发。
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-31 DOI: 10.1186/s12890-026-04150-0
Emine Afşin, Şeref Özkara, Fatma Ceren Gökdemir
{"title":"Isoniazid-induced alopecia in isoniazid-monoresistant pulmonary tuberculosis.","authors":"Emine Afşin, Şeref Özkara, Fatma Ceren Gökdemir","doi":"10.1186/s12890-026-04150-0","DOIUrl":"https://doi.org/10.1186/s12890-026-04150-0","url":null,"abstract":"","PeriodicalId":9148,"journal":{"name":"BMC Pulmonary Medicine","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mobile phone auscultation to delineate pneumonia from other respiratory conditions and controls: a prospective cohort study. 手机听诊与其他呼吸系统疾病和对照：一项前瞻性队列研究。
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-30 DOI: 10.1186/s12890-026-04135-z
Martin Huecker, Ryan Close, Jonathan Mattingly, Haely Studebaker, Craig Zeigler, Daniel O'Brien, Jeremy Thomas
{"title":"Mobile phone auscultation to delineate pneumonia from other respiratory conditions and controls: a prospective cohort study.","authors":"Martin Huecker, Ryan Close, Jonathan Mattingly, Haely Studebaker, Craig Zeigler, Daniel O'Brien, Jeremy Thomas","doi":"10.1186/s12890-026-04135-z","DOIUrl":"https://doi.org/10.1186/s12890-026-04135-z","url":null,"abstract":"","PeriodicalId":9148,"journal":{"name":"BMC Pulmonary Medicine","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146084210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elevated MMP2 expression in fibrotic interstitial lung disease: a potential biomarker for assessment of disease severity. 纤维化间质性肺疾病中MMP2表达升高：评估疾病严重程度的潜在生物标志物
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-29 DOI: 10.1186/s12890-026-04139-9
Yiying Huang, Tianbai Niu, Jiawen Yang, Yining Liu, Zehu Chen, Kongqiu Wang, Xiaobin Zheng, Xuegang Li, Jing Liu
{"title":"Elevated MMP2 expression in fibrotic interstitial lung disease: a potential biomarker for assessment of disease severity.","authors":"Yiying Huang, Tianbai Niu, Jiawen Yang, Yining Liu, Zehu Chen, Kongqiu Wang, Xiaobin Zheng, Xuegang Li, Jing Liu","doi":"10.1186/s12890-026-04139-9","DOIUrl":"https://doi.org/10.1186/s12890-026-04139-9","url":null,"abstract":"","PeriodicalId":9148,"journal":{"name":"BMC Pulmonary Medicine","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146084242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Self‑report underestimates the frequency of the acute respiratory exacerbations of COPD but is associated with BAL neutrophilia and lymphocytosis: an observational study. 更正：自我报告低估了COPD急性呼吸恶化的频率，但与BAL嗜中性粒细胞增多和淋巴细胞增多有关：一项观察性研究。
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-29 DOI: 10.1186/s12890-025-04076-z
Yorusaliem Abrham, Siyang Zeng, Wendy Lin, Colin Lo, Alexander Beckert, Laurel Evans, Michelle Dunn, Brian Giang, Krish Thakkar, Julian Roman, Paul D Blanc, Mehrdad Arjomandi
{"title":"Correction: Self‑report underestimates the frequency of the acute respiratory exacerbations of COPD but is associated with BAL neutrophilia and lymphocytosis: an observational study.","authors":"Yorusaliem Abrham, Siyang Zeng, Wendy Lin, Colin Lo, Alexander Beckert, Laurel Evans, Michelle Dunn, Brian Giang, Krish Thakkar, Julian Roman, Paul D Blanc, Mehrdad Arjomandi","doi":"10.1186/s12890-025-04076-z","DOIUrl":"10.1186/s12890-025-04076-z","url":null,"abstract":"","PeriodicalId":9148,"journal":{"name":"BMC Pulmonary Medicine","volume":"26 1","pages":"31"},"PeriodicalIF":2.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12853590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146084273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Voriconazole-Induced acute interstitial pulmonary edema with angioedema: A case report. 伏立康唑致急性间质性肺水肿伴血管性水肿1例。
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-29 DOI: 10.1186/s12890-026-04141-1
Yuzhen Jin, Lijie Qin, Peng Liu, Zhaoxia Song, Mengjie Li

Background: Voriconazole is a first-line antifungal agent for invasive fungal infections. Reports of voriconazole-induced interstitial pulmonary edema are exceedingly rare.

Case presentation: We describe a 74-year-old woman with pneumonia who developed facial edema, dyspnea, and pink frothy sputum after four days of voriconazole therapy. Chest computed tomography (CT) revealed bilateral pleural effusions and interlobular septal thickening. She was initially misdiagnosed with acute heart failure, but failed to respond to diuretics. Both B-type natriuretic peptide (BNP) levels and echocardiography were unremarkable. The diagnosis of voriconazole-induced acute interstitial pulmonary edema was established. Voriconazole withdrawal and corticosteroid therapy resulted in rapid clinical resolution.

Conclusion: Voriconazole hypersensitivity may manifest as acute interstitial pulmonary edema with concomitant angioedema, a presentation that can mimic cardiogenic pulmonary edema. Early recognition and timely corticosteroid intervention are crucial for favorable outcomes.

背景：伏立康唑是治疗侵袭性真菌感染的一线抗真菌药物。伏立康唑引起间质性肺水肿的报道极为罕见。病例介绍：我们描述了一位74岁的肺炎女性，她在接受伏立康唑治疗4天后出现面部水肿、呼吸困难和粉红色泡沫痰。胸部电脑断层扫描显示双侧胸腔积液及小叶间隔增厚。她最初被误诊为急性心力衰竭，但对利尿剂没有反应。b型利钠肽（BNP）水平及超声心动图均无明显差异。建立伏立康唑致急性间质性肺水肿的诊断。戒除伏立康唑和皮质类固醇治疗导致快速临床解决。结论：伏立康唑超敏反应可能表现为急性间质性肺水肿并伴有血管性水肿，其表现类似心源性肺水肿。早期识别和及时的皮质类固醇干预是获得良好结果的关键。
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引用次数: 0
Correction: LncNFYC-AS1 ameliorates Mycoplasma pneumoniae pneumonia via regulating miR- 1323. 更正：LncNFYC-AS1通过调节miR- 1323改善肺炎支原体肺炎。
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-29 DOI: 10.1186/s12890-025-04073-2
Cai Chen, Jianping Hu, Mao Guo, Li Li, Qihong Yang
{"title":"Correction: LncNFYC-AS1 ameliorates Mycoplasma pneumoniae pneumonia via regulating miR- 1323.","authors":"Cai Chen, Jianping Hu, Mao Guo, Li Li, Qihong Yang","doi":"10.1186/s12890-025-04073-2","DOIUrl":"10.1186/s12890-025-04073-2","url":null,"abstract":"","PeriodicalId":9148,"journal":{"name":"BMC Pulmonary Medicine","volume":"26 1","pages":"32"},"PeriodicalIF":2.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12857143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146084187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic assessment of the COPD patient: it is time to consider respiratory muscle ultrasound. 慢性阻塞性肺病患者的预后评估：是时候考虑呼吸肌超声了。
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-29 DOI: 10.1186/s12890-026-04118-0
Zeyang Dong, Mengyao Zhao, Xixi Sun, Xianting Yan, Sihui Zheng, Jian Ye, Bin Huang, Jin Ge
{"title":"Prognostic assessment of the COPD patient: it is time to consider respiratory muscle ultrasound.","authors":"Zeyang Dong, Mengyao Zhao, Xixi Sun, Xianting Yan, Sihui Zheng, Jian Ye, Bin Huang, Jin Ge","doi":"10.1186/s12890-026-04118-0","DOIUrl":"https://doi.org/10.1186/s12890-026-04118-0","url":null,"abstract":"","PeriodicalId":9148,"journal":{"name":"BMC Pulmonary Medicine","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146084204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinct comorbidity profiles and outcomes in asbestosis versus idiopathic pulmonary fibrosis: a 6-year prospective cohort study. 石棉沉滞症与特发性肺纤维化的独特合并症概况和结果：一项为期6年的前瞻性队列研究
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-29 DOI: 10.1186/s12890-025-04070-5
Yawen Song, Yuanying Wang, Nafeisa Dilixiati, Dongmei Wang, Yiran Wang, Qiao Ye

Background: Asbestosis and idiopathic pulmonary fibrosis (IPF) share overlapping clinical and pathological features; however, differences in comorbidities and prognostic patterns between the two diseases remain poorly defined. This study aimed to compare comorbidities and prognostic factors associated with pulmonary fibrosis progression and mortality in asbestosis and IPF.

Methods: This prospective cohort study included 254 patients with asbestosis and 548 patients with IPF enrolled between 2016 and 2020, with follow-up through 2022. Outcomes included progressive pulmonary fibrosis (PPF) and all-cause mortality. Multivariable Cox models were applied to identify independent risk factors associated with these outcomes.

Results: Patients with asbestosis exhibited a higher comorbidity burden. Specifically, they more frequently had asthma, lung cancer, pleural disease, cardiovascular/cerebrovascular disease, and connective tissue disease, whereas emphysema was more common in IPF (all P < 0.05). Over a median follow-up of 44 months (IQR 24-61), IPF patients had a higher cumulative incidence of endpoint events than those with asbestosis. In asbestosis, a usual interstitial pneumonia (UIP) pattern on HRCT predicted disease progression. In IPF, risk factors for progression included hypoxemia, forced vital capacity (FVC) < 80%, and UIP compared with probable UIP. Interestingly, combined emphysema was protective against IPF progression. Mortality in asbestosis was associated with lung cancer, pulmonary hypertension (PH), and atrial fibrillation, whereas in IPF, it was linked to FVC < 80% and PH.

Conclusions: Asbestosis and IPF show distinct comorbidity patterns and prognostic drivers. IPF prognosis is mainly determined by fibrosis severity, while asbestosis mortality is driven largely by asbestos-related complications.

背景：石棉肺和特发性肺纤维化（IPF）具有重叠的临床和病理特征；然而，两种疾病的合并症和预后模式的差异仍然不明确。本研究旨在比较石棉沉滞和IPF中与肺纤维化进展和死亡率相关的合并症和预后因素。方法：这项前瞻性队列研究纳入了2016年至2020年间入选的254例石棉沉滞患者和548例IPF患者，随访至2022年。结果包括进行性肺纤维化（PPF）和全因死亡率。应用多变量Cox模型确定与这些结果相关的独立危险因素。结果：石棉沉滞患者表现出较高的合并症负担。具体来说，他们更常患有哮喘、肺癌、胸膜疾病、心脑血管疾病和结缔组织疾病，而肺气肿在IPF中更常见(所有P结论：石棉肺和IPF表现出不同的合并症模式和预后驱动因素。IPF的预后主要由纤维化严重程度决定，而石棉肺的死亡率主要由石棉相关并发症驱动。
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引用次数: 0
The effect of respiratory training on lung function in intensive care unit patients: a systematic review and meta-analysis. 呼吸训练对重症监护病房患者肺功能的影响：系统回顾和荟萃分析。
IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
BMC Pulmonary Medicine
Pub Date : 2026-01-27 DOI: 10.1186/s12890-026-04122-4
Hejin Yang, Hui Huang, Wenjuan Dai, Lizhu Wei, Miao Huang, Lihong Yuan
{"title":"The effect of respiratory training on lung function in intensive care unit patients: a systematic review and meta-analysis.","authors":"Hejin Yang, Hui Huang, Wenjuan Dai, Lizhu Wei, Miao Huang, Lihong Yuan","doi":"10.1186/s12890-026-04122-4","DOIUrl":"https://doi.org/10.1186/s12890-026-04122-4","url":null,"abstract":"","PeriodicalId":9148,"journal":{"name":"BMC Pulmonary Medicine","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146060053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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