International journal of innovative medicine and health science最新文献

{"title":"THE USAGE OF THE FINITE ELEMENT ANALYSIS IN THE DESIGN OF NEW DENTAL IMPLANT SYSTEMS","authors":"Y. Sergeev, A. Dolgalev, D. Choniashvili, V. Avanisyan","doi":"10.33667/2782-4101-2023-1-19-23","DOIUrl":"https://doi.org/10.33667/2782-4101-2023-1-19-23","url":null,"abstract":"Introduction. The development of new dental implants in the context of the booming domestic industry makes it possible to find alternative options in the treatment of clinically difficult situations, to select the necessary individual solution during dental implant surgery and consequently to perform the surgery in an error-free manner and achieve the desired results. The development of a dental implant is a multistep process, and the characteristics of the implant material and its biophysical characteristics must be studied in detail until the implant is integrated into the bone tissue.The aim of the study: to estimate the opportunities and prospects of applying the finite elements method by developing the new systems of dental implants according to the literature data.Materials and methods. A search was carried out in the national digital libraries e-library, CyberLeninka, as well as PubMed, Medline, Web of Science and Google Scholar using the following keywords: dental implant, finiteelement analysis, mathematical model. Sixty-nine papers were selected and analysed.Results. The finite element method is an accurate method to analyse the implant being developed, but it has certain limitations, because in the finite element mesh, the implant-bone interface is a continuous relationship. The absence of micro-movement at the implant-bone interface during loading is different from the actual clinical situation. The expected 100 % osseointegration based on 3D-modelling can’t be an ideal option and never corresponds to the reality in the clinical situation. However, the use of the finite element method makes it possible to test single loads and inclination angles, which in the clinical situation is very rare","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"15 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91208828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STATIC STRENGTH ESTIMATE OF STRUCTURAL ELEMENTS OF IMPLANT SYSTEMS LIKO 4 × 10 OF VARIOUS DESIGNS","authors":"A. A. Sarkisov, V. Avanisyan, A. Dolgalev, Y. Sergeev","doi":"10.33667/2782-4101-2023-1-10-14","DOIUrl":"https://doi.org/10.33667/2782-4101-2023-1-10-14","url":null,"abstract":"Introduction. The creation of effective, reliable, safe, technologically advanced and competitive products is the main task of medical device engineering. The most important requirement to modern medical devices is to guarantee patients’ safety during their lifetime. Today the use of modern computer-aided engineering analysis packages is the most effective calculation method for evaluating the strength and reliability of unique medical devices that can lead to serious consequences if their operation is disturbed. One of the most suitable and efficient systems for computer-aided engineering (CAE) system is the ANSYS software.The purpose of this study was the comparative assessment of the elastic and elastoplastic formation of 4x10 dental implants of different designs on the abutment-pin and screw-body interface, using the computer simulation of the stress-strain state.Materials and methods. Two kinds of dental implants were chosen for this study: a Liko-M 4 × 10 implant with the cylindrical body shape and a Liko-M DG 4 × 10 implant with a tapered body shape. The contact between the abutment and screw as well as the implant body and screw is frictional. The pre-tensioning of the screw from the initial tightening was 400 N. The load was applied to the cylindrical surface of the abutment at a percentage of its height.Results. Elastic and elasto-plastic calculations of the stress-strain state of Liko-M 4 × 10 and Liko-M DG 4 × 10 implants were performed. Besides the results of the main calculations of the stress-strain state of the implants Liko-M 4x10 and Liko-M DG 4 × 10, necessary to assess their static strength, we have also calculated the strength coefficients of implant bodies. Comparative analysis of the static strength of the Liko-M 4 × 10 and Liko-M DG 4 × 10 implants provides conclusions, which are significant for practical application of the implants.","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"217 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72674150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"REAL-TIME POLYMERASE CHAIN REACTION (PCR) APPLICATION FOR THE DETECTION OF PERIODONTOPATOGENS","authors":"E. Jafarov, A. Dolgalev, U. B. Edisherashvili, M. Z. Choniashvili, D. T. Taimazova","doi":"10.33667/2782-4101-2023-1-7-9","DOIUrl":"https://doi.org/10.33667/2782-4101-2023-1-7-9","url":null,"abstract":"The ethiological factor of periodontal diseases is the presence of periodontopathogens; in state of imbalance with commensals they begin to affect pathologically. With a decrease in the number of periodontopathogens in the biofilm, it is possible to restore the balance and prevent periodontal diseases or their transition to the stage of remission. Nowadays, the most informative and accessible diagnostic method for determining periodontopathogens is real-time polymerase chain reaction (PCR).","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89674131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARATIVE STATIC STRENGTH EVALUATION OF THE IMPLANT-ABUTMENT JOINTS IN DIFFERENT IMPLANT DESIGNS","authors":"A. A. Elkanov, A. Dolgalev, Y. Sergeev, V. Avanisyan","doi":"10.33667/2782-4101-2023-1-4-6","DOIUrl":"https://doi.org/10.33667/2782-4101-2023-1-4-6","url":null,"abstract":"Nowadays the problem of optimal restorative prosthetics on dental implants is of paramount importance for solving a number of clinically difficult cases and extends beyond the alternative treatment at the complete and partial adentia both on the upper and lower jaws. An essential factor here is understanding of the biomechanical behaviour of the implant-abutment interface, because an optimal implant-abutment interface simulates the biophysical behaviour of natural teeth and ensures the long-term function of the prosthetic restoration. The optimal method for assessing the implant-abutment junction is the static tensile strength method. The limit is determined by performing a single loading of the dental implant in the implant-abutment area.The aim of the study was to assess the implant-abutment deformation of demountable and non-demountable structures of the 4x10 cylindrical and cone-shaped dental implants with determination of their static strength limit.Materials and methods. Two brands of dental implants have been chosen as the objects of research – cylindrical implant LIKO M 4x10 and cone-shaped implant LIKO M DG 4x10. A subject of the research is the ultimate strength of the implant-abutment unit of demountable and non-demountable abutment design.Results. Static loading tests with estimation of the deformation limit of the implant-abutment unit were carried out along with the comparative estimation of the strength of demountable and non-demountable abutment constructions of dental implants of various shapes.Conclusion. The carried out comparative analysis of the static strength makes it possible to optimise the process of prosthodontic treatment on dental implants taking into account the maximal limits of the loaded structures and to carry out the equilibrium load distribution.","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"256 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73518383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NOVEL METHOD FOR QUANTIFYING HEPATIC STEATOSIS IN PATIENTS WITH METABOLICALLY ASSOCIATED FATTY LIVER DISEASE","authors":"A. Borsukov, D. Venidiktova, S. Borsukov","doi":"10.33667/2782-4101-2022-2-12-16","DOIUrl":"https://doi.org/10.33667/2782-4101-2022-2-12-16","url":null,"abstract":"Introduction. The article presents an overview of novel complex algorithm based on methods of ultrasound steatometry, combined elastography and dual-energy X-ray absorbtiometry in “Whole body” mode in diagnostic and monitoring of metabolically associated fatty liver disease.The purpose of the study: to assess the possibility of quantitative ultrasound steatometry using in the detection and monitoring of metabolically associated fatty liver disease.Material and methods. 157 patients were examined. The main group consisted of 47 patients with liver steatosis; 45 patients with steatohepatitis and clinically insignificant liver fibrosis (F0-F1); 32 patients with steatohepatitis and clinically significant liver fibrosis (F2-F3); 33 patients with focal hepatic steatosis. We used complex algorithm based on methods of questionnaires, laboratory tests, ultrasound steatometry, combined elastography and dual-energy x-ray absorbtiometry in “Whole body” mode, liver biopsy. to determine the severity of steatosis, a scale was used: S0 – no steatosis; 2.9 dB/cm.Results and conclusion. It is possible to use quantitative ultrasound steatometry for metabolically associated fatty liver disease, as a reference method both for the initial detection of the disease and for monitoring non-drug treatment (sensitivity 90.7%, specificity 92.4%). The optimal complex for the diagnosis and monitoring of non-drug treatment of metabolically associated fatty liver disease includes an assessment of the level of compliance, the use of quantitative ultrasound steatometry and dual-energy X-ray absorptiometry in the «Whole body» mode (sensitivity 92.8%, specificity 92.3%).","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87729766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RESULTS of MORPHOLOGICAL ANALYSIS of ANIMAL HARD TISSUES IN NORMAL AND SIMULATED OSTEOPOROSIS USING A NON-INVASIVE COMPUTED MICROTOMOGRAPHY TECHNIQUE","authors":"A. Dolgalev, I. Rzhepakovsky, A. Danaev, V. Avanisyan, G. Shulga, A. Korobkeev","doi":"10.33667/2782-4101-2022-2-17-21","DOIUrl":"https://doi.org/10.33667/2782-4101-2022-2-17-21","url":null,"abstract":"Introduction. X-ray microtomography is a non-destructive method of microstructural analysis, which has a high level of detail and allows the possibility of assessing the internal architecture of organs and tissues using 3D-analysis[1]. The specifics of working with such equipment can be divided into in vivo and in vitro, i.e. working with live laboratory animals (mice, rats, rabbits) under anesthesia or studying organs and tissues separated from the animal [2].The aim of the work was to study the microstructure of sheep bone tissues in normal and simulated osteoporosis using computed microtomography.Materials and methods. We performed microCT analysis of different sheep bones in normal and experimental osteoporosis. Bone tissue of the jaw, iliac and femur, and teeth were collected from control and experimental animals. Bone tissue samples were fixed in 10% buffered formalin. X-ray microCT scanner Skyscan 1176 (BrukermicroCT, Belgium) and software Skyscan 1176 control program (10.0.0.0), Nrecon (1.7.4.2), DataViewer (1.5.6.2), CT-analyser (1.18.4.0), CTvox (3.3.0r1403) were used to scan and process materials.Results. MicroCT examination and 3D-imaging confirmed the elimination of trabeculae in the metaphyseal region of the femur in sheep with experimental osteoporosis from the centre to the periphery; in addition, 3D-analysis showed a 15.1% decrease in bone percentage, a 7.8% decrease in bone mineral density, and an increase in Tb. Sp. (trabecular separation), Tb. Pf. (trabecular pattern factor) and SMI (structure model index) by 30.2%, 20.8% and 23.6%, respectively, and a decrease in Tb.N. (trabecular number) index by 18.6%, indicating calcium washout, decreased trabecular connectivity and a transition from a lamellar to a rod-like architecture. Similar changes were found in the 3D-analysis of the jaw bone tissue. Thus, a decrease of 18.9% in mineral density was found, as well as a significant increase of 11.58 and 2.21 in the indices, particularly Tb. Pf. and SMI. 3D-analysis of iliac microtomography also indicates a simulation of osteoporosis, as evidenced by a significant increase in the main indices characterising the development of this pathology.Conclusions. The obtained results not only objectively testify to the development of osteoporosis in the experimental animals, but also indicate signs of the adaptation-compensatory reactions of the body, characterized by appearance of large single trabeculae in the metaphysis of the femur as well as by not expressed reduction of bone mineral density and bone tissue area.","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81893158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE EFFECT of HIGH-INTENSITY INTERVAL PHYSICAL TRAINING ON THE ENERGY SUPPLY SYSTEM IN PATIENTS AFTER HEART SURGERY","authors":"A. Kuular, T. Kakuchaya, T. Dzhitava, A. Filatova, N. Pachuashvili","doi":"10.33667/2782-4101-2022-2-4-8","DOIUrl":"https://doi.org/10.33667/2782-4101-2022-2-4-8","url":null,"abstract":"Introduction. A number of studies have found a reduction in the risk of rehospitalization during cardiorehabilitation after heart surgery. The purpose of the training program for cardiorehabilitation after cardiac surgery is to optimize energy supply systems. Depending on the intensity and duration of the load being performed, energy supply systems 'switch on' in the body.Purpose of the study: to study the effectiveness of the optimal cardiorehabilitation training program on the aerobic energy supply system in cardiac surgery patients.Materials and methods. In our study, we examined 47 patients who underwent aortic valve replacement under cardiopulmonary bypass, with an EC duration of 52±20.5 minutes. The patients were divided into two groups: the control group (n=23), who underwent a course of cardiorehabilitation on exercise bikes with constant aerobic training of moderate and medium intensity, at the age of 50.2±3.4 years, and the main group (n=24) – with a course of cardiorehabilitation on exercise bikes with aerobic high-intensity interval physical training, at the age of 51.2±2.8 years (p>0.05). Gender was not taken into account. Anaerobic training was carried out on SCHILLER exercise bikes from day 14 after aortic valve replacement. The load power ranged from 25 to 70–95 watts. Before cardiac rehabilitation, the level of lactate, glucose, pH, pCO2, pO2, BE, lipid profile, BNP in the blood before and after ergometric exercise, data on external respiration, heart rate and blood pressure were assessed. After the course of rehabilitation, the above parameters were evaluated. The duration of the course was 2 weeks. Results. When evaluating the indicators at the end of the course of cardiorehabilitation was being done, a significant decrease in the controlled parameters after training was observed in both groups, and largely in the group of high-intensity interval physical training than in the group of constant training of medium intensity.Conclusions. Analysis of the results showed that properly selected parameters of high-intensity interval training could optimize anaerobic glycolysis in patients undergoing operations under cardiopulmonary bypass, as well as increase the functionality of patients. As more and more repetitions of the load are performed, interval training becomes more and more aerobic.","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75004440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TISSUE-ENGINEERED BONE IMPLANTS FOR THE REPLACEMENT OF JAWBONE DEFECTS. LITERATURE REVIEW","authors":"K. Kobets, A. Kazaryan, S. Bopkhoev","doi":"10.33667/2782-4101-2022-2-21-26","DOIUrl":"https://doi.org/10.33667/2782-4101-2022-2-21-26","url":null,"abstract":"The purpose of the study: to trace the development of methods of bone implants for the replacement of jawbone defects: from ceramic and polymeric scaffolds to complex tissue-engineered structures with stem cells, growth factors and vascular anastomoses based on literature data.Materials and methods: searching, systematization and analysis of scientific data on various types of 3D-printed bone implants and their effectiveness in replacing bone defects.Conclusions: Modern technologies of 3D-printing, cell and tissue engineering, microvascular surgical techniques closely approach scientists and clinicians to creation of an artificial bone implant which in the body must become a living structure capable of integrating with the patient’s bone. Only complex approach which includes reconstruction of the implant of individual shape and sufficient mechanical strength, giving of osteoinductive and osteogenic properties, providing of internal axial and external angiogenesis is the basis for such tissue-engineered construction.","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79877139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE CHOICE OF A PERSONALIZED METHOD IN THE DIAGNOSTICS OF BREAST CANCER IN A CYST BY MEANS OF HYBRID TECHNOLOGIES UNDER ULTRASOUND NAVIGATION","authors":"M. Arabachyan, A. Borsukov","doi":"10.33667/2782-4101-2022-2-9-11","DOIUrl":"https://doi.org/10.33667/2782-4101-2022-2-9-11","url":null,"abstract":"The article presents the results of the use of a new improved method of cytologic diagnostics of cancer in a breast cyst by applying hybrid technologies. By using our new created method with the application of ozone-oxygen mixture, unlike the traditional method of fine needle aspiration biopsy of breast cysts with a solid parietal component, the probability of obtaining unaltered atypical cells in the punctate in the presence of malignization increases, thereby promoting the informativeness and sensitivity of this diagnostic method.","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88442743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"POST-STROKE MOTOR IMPAIRMENTS: THE POSSIBILITIES OF INNOVATIVE TECHNOLOGIES AND THE RESULTS OF THE OWN RESEARCH","authors":"E. Kostenko, L. Petrova, A. Rylsky","doi":"10.33667/2782-4101-2022-1-4-10","DOIUrl":"https://doi.org/10.33667/2782-4101-2022-1-4-10","url":null,"abstract":"Introduction.The article presents an overview of innovative technologies based on methods sensomotor retraining of the patient using neuromuscular electrical stimulation (NFES) and biofeedback (BFB) as the most promising in the medical rehabilitation (MR) of motor impairment in patients with brain stroke (BS). The results of our own study are also presented.The aim of the study - an assessment of the effectiveness of a comprehensive rehabilitation program with the inclusion of NFES and stabilometric postural control using the BFB method in patients with after-stroke motor disfunction in the chronic ischemic stroke (IS).Material and methods. We examined 87 patients (41 women and 46 men) in the chronic IS, mean age 58.4±6.4 years. The stroke duration was 228.59±31.9 days. The main group included 52 patients who, along with the standard treatment regimen, underwent NFES and BFB-stabilometric training. The comparison group consisted of 35 patients whose rehabilitation complex did not include the above methods.Results and conclusion. Due to comlex rehabilitation with NFES and BFB stabilometric postural training it has been improved the function of walking. The clinical effect was noted 3 weeks after the start of rehabilitation, reaching a maximum by the 5th week. The inclusion of BFB-based methods in the medical rehabilitation leads to earlier motor and social adaptation of the after-stroke patient, restoration of the impairment balance function, which is associated with an increase in neuroplasticity.","PeriodicalId":91707,"journal":{"name":"International journal of innovative medicine and health science","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81737416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}