Pub Date : 2026-03-18DOI: 10.1186/s12872-026-05741-9
Haikal Balweel, Surya Sinaga Immanuel, Jordan Budiono, Clarissa Cusan, Jesslyn Ellenia Gotama, Novaro Adeneur Tafriend, Agus Harsoyo
{"title":"Potential use of ivabradine in postoperative junctional ectopic tachycardia: a systematic review and single-arm meta-analysis.","authors":"Haikal Balweel, Surya Sinaga Immanuel, Jordan Budiono, Clarissa Cusan, Jesslyn Ellenia Gotama, Novaro Adeneur Tafriend, Agus Harsoyo","doi":"10.1186/s12872-026-05741-9","DOIUrl":"https://doi.org/10.1186/s12872-026-05741-9","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147472637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-18DOI: 10.1186/s12872-026-05736-6
Deborah Oke, Okechukwu Ogah, Yusuf Bello, Oluwatosin Lawal, Yusuf Kareem, Ololade Adeyemi, Oluwatoyin Olalemi, Babatunde Adedokun, Babatunde Salako, Isaac Adewole, Deborah Watson-Jones, Imran Morhason-Bello
{"title":"Patterns of blood pressure and factors associated with hypertension among young adults in Ibadan, Nigeria.","authors":"Deborah Oke, Okechukwu Ogah, Yusuf Bello, Oluwatosin Lawal, Yusuf Kareem, Ololade Adeyemi, Oluwatoyin Olalemi, Babatunde Adedokun, Babatunde Salako, Isaac Adewole, Deborah Watson-Jones, Imran Morhason-Bello","doi":"10.1186/s12872-026-05736-6","DOIUrl":"https://doi.org/10.1186/s12872-026-05736-6","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-18DOI: 10.1186/s12872-026-05727-7
Wei-Feng Yan, Xue-Ming Li, Yue Gao, Li Jiang, Rong Xu, Shi-Qin Yu, Jia-Ke Li, Yuan Li, Jin Wang, Zhi-Gang Yang
{"title":"Gender differences in asymptomatic hyperuricemia's effects on left ventricular function and remodeling in hypertension: insights from cardiac MRI.","authors":"Wei-Feng Yan, Xue-Ming Li, Yue Gao, Li Jiang, Rong Xu, Shi-Qin Yu, Jia-Ke Li, Yuan Li, Jin Wang, Zhi-Gang Yang","doi":"10.1186/s12872-026-05727-7","DOIUrl":"https://doi.org/10.1186/s12872-026-05727-7","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147472591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-18DOI: 10.1186/s12872-026-05747-3
Wei Zhang, Kaihang Xu, Shiguang Liu, Juan Chen, Hua Jiang
{"title":"A novel duplication frameshift mutation in the BAG3 gene in a patient with dilated cardiomyopathy.","authors":"Wei Zhang, Kaihang Xu, Shiguang Liu, Juan Chen, Hua Jiang","doi":"10.1186/s12872-026-05747-3","DOIUrl":"https://doi.org/10.1186/s12872-026-05747-3","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-17DOI: 10.1186/s12872-026-05673-4
José Fernando Vilela-Martin, Tatiana Palotta Minari, Marco Antônio Vieira da Silva, Valquíria da Silva Lopes, Kléber Aparecido de Oliveira, Marco Aurélio de Almeida, Riccardo Lacchini, José Eduardo Tanus-Santos, Heitor Moreno, Juan Carlos Yugar-Toledo, Luciana Neves Cosenso-Martin
Ambulatory blood pressure monitoring (ABPM), alongside peripheral blood pressure (BP) measurements, provides valuable insights into central hemodynamics, including pulse wave velocity (PWV), augmentation index (AI75%), and central pressure-factors closely linked to arterial stiffness. The progression of arterial stiffness is associated with matrix metalloproteinase-9 (MMP-9), an extracellular matrix enzyme. This study aims to assess the correlation between variables obtained through ABPM and MMP-9 levels across different BP categories. A total of 101 individuals were enrolled, divided into three groups: 21 normotensive (NT), 36 prehypertensive (PH), and 44 controlled hypertensive (CHT) participants. Peripheral and central BP parameters were evaluated using the Mobil-O-Graph® 24-hour PWA monitor, and plasma MMP-9 levels were measured in all participants. Participants' ages ranged from 30 to 71 years. MMP-9 concentrations were significantly higher in the PH group (4.74 ± 0.5 ng/mL) compared to the CHT group (4.41 ± 0.5 ng/mL; p = 0.002). MMP-9 levels showed a correlation with cardiac output and heart rate during all three ABPM evaluation periods (24 h, wakefulness, and sleep). PWV values were higher in the CHT group than in the PH group (8.1 ± 1.2 vs. 6.9 ± 1; p = 0.0003), whereas AI75% did not differ significantly between the groups (22.6 ± 8.9 vs. 19.8 ± 7.4; p = NS). Prehypertensive individuals exhibit higher MMP-9 levels compared to controlled hypertensive patients, suggesting that antihypertensive therapy may contribute to reduced plasma MMP-9 levels.
动态血压监测（ABPM）与外周血压（BP）测量一起，提供了对中心血流动力学的有价值的见解，包括脉搏波速度（PWV）、增强指数（AI75%）和与动脉硬度密切相关的中心压力因素。动脉硬化的进展与基质金属蛋白酶-9 （MMP-9）有关，这是一种细胞外基质酶。本研究旨在评估通过ABPM获得的变量与不同BP类别的MMP-9水平之间的相关性。共有101人被纳入研究，分为三组：21名正常血压（NT）、36名高血压前期（PH）和44名高血压控制（CHT）参与者。使用mobile - o - graph®24小时PWA监测仪评估外周和中枢血压参数，并测量所有参与者的血浆MMP-9水平。参与者的年龄从30岁到71岁不等。PH组MMP-9浓度（4.74±0.5 ng/mL）显著高于CHT组（4.41±0.5 ng/mL, p = 0.002）。在所有三个ABPM评估期间（24小时、清醒和睡眠），MMP-9水平与心输出量和心率相关。CHT组PWV值高于PH组（8.1±1.2 vs. 6.9±1,p = 0.0003），而AI75%组间差异无统计学意义（22.6±8.9 vs. 19.8±7.4,p = NS）。与控制高血压的患者相比，高血压前期个体表现出更高的MMP-9水平，这表明抗高血压治疗可能有助于降低血浆MMP-9水平。
{"title":"Effects of antihypertensive therapy on matrix metalloproteinase-9 levels in controlled hypertensive patients.","authors":"José Fernando Vilela-Martin, Tatiana Palotta Minari, Marco Antônio Vieira da Silva, Valquíria da Silva Lopes, Kléber Aparecido de Oliveira, Marco Aurélio de Almeida, Riccardo Lacchini, José Eduardo Tanus-Santos, Heitor Moreno, Juan Carlos Yugar-Toledo, Luciana Neves Cosenso-Martin","doi":"10.1186/s12872-026-05673-4","DOIUrl":"https://doi.org/10.1186/s12872-026-05673-4","url":null,"abstract":"<p><p>Ambulatory blood pressure monitoring (ABPM), alongside peripheral blood pressure (BP) measurements, provides valuable insights into central hemodynamics, including pulse wave velocity (PWV), augmentation index (AI75%), and central pressure-factors closely linked to arterial stiffness. The progression of arterial stiffness is associated with matrix metalloproteinase-9 (MMP-9), an extracellular matrix enzyme. This study aims to assess the correlation between variables obtained through ABPM and MMP-9 levels across different BP categories. A total of 101 individuals were enrolled, divided into three groups: 21 normotensive (NT), 36 prehypertensive (PH), and 44 controlled hypertensive (CHT) participants. Peripheral and central BP parameters were evaluated using the Mobil-O-Graph<sup>®</sup> 24-hour PWA monitor, and plasma MMP-9 levels were measured in all participants. Participants' ages ranged from 30 to 71 years. MMP-9 concentrations were significantly higher in the PH group (4.74 ± 0.5 ng/mL) compared to the CHT group (4.41 ± 0.5 ng/mL; p = 0.002). MMP-9 levels showed a correlation with cardiac output and heart rate during all three ABPM evaluation periods (24 h, wakefulness, and sleep). PWV values were higher in the CHT group than in the PH group (8.1 ± 1.2 vs. 6.9 ± 1; p = 0.0003), whereas AI75% did not differ significantly between the groups (22.6 ± 8.9 vs. 19.8 ± 7.4; p = NS). Prehypertensive individuals exhibit higher MMP-9 levels compared to controlled hypertensive patients, suggesting that antihypertensive therapy may contribute to reduced plasma MMP-9 levels.</p>","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147472643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-16DOI: 10.1186/s12872-026-05744-6
Meltem Uyaner Kan, Hasan Kan, Yakup Alsancak, Filiz Alkan Baylan
{"title":"Mitral stenosis severity and the hypoxic response: potential role of hypoxia-inducible factor-2α - a cross-sectional study.","authors":"Meltem Uyaner Kan, Hasan Kan, Yakup Alsancak, Filiz Alkan Baylan","doi":"10.1186/s12872-026-05744-6","DOIUrl":"https://doi.org/10.1186/s12872-026-05744-6","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147466941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new diagnostic prediction model for infective endocarditis based on the 2023 duke-international society for cardiovascular infectious disease criteria: a multicenter observational study.","authors":"Shun Yamashita, Ryosuke Osako, Takanori Yamaguchi, Yoshinori Tokushima, Yukinori Harada, Taiju Miyagami, Yosuke Sasaki, Yasutomo Oda, Masaki Tago","doi":"10.1186/s12872-026-05742-8","DOIUrl":"https://doi.org/10.1186/s12872-026-05742-8","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147466824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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