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BMC Cardiovascular Disorders最新文献

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A cross-sectional study: carotid artery stiffness in individuals with varying cardiovascular disease risk using shear wave elasticity. 横断面研究：使用剪切波弹性在不同心血管疾病风险个体的颈动脉僵硬度
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-04 DOI: 10.1186/s12872-026-05547-9
Chuanjian Chen, Junni Shi, Yanchun Xie, Lixia Zhang, Shengnan Li, Yunqian Huang, Man Chen
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引用次数: 0
Association of triglyceride-glucose index with carotid atherosclerosis in the general population: a case-control study of 14,535 participants. 甘油三酯-葡萄糖指数与普通人群颈动脉粥样硬化的关系：14535名参与者的病例对照研究
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-04 DOI: 10.1186/s12872-026-05581-7
Hong Wang, Zhihong Ma, Siqi Ge, Junping Tian
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引用次数: 0
Study of the prognostic value of the systemic immune-inflammation index combined with the triglyceride-glucose index in coronary heart disease: a retrospective study based on the MIMIC database. 全身免疫-炎症指数联合甘油三酯-葡萄糖指数对冠心病预后价值的研究：基于MIMIC数据库的回顾性研究
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-04 DOI: 10.1186/s12872-026-05544-y
Chen-Yang Wu, Yu-Qin Zhan, Yu-Bin Shen, Ting-Shan Yu, Ya-Hui Ding

Background: The combined impact of the systemic immune-inflammation index (SII) and the triglyceride-glucose index (TyG) on short- and long-term outcomes in patients with coronary heart disease (CHD) remains unclear. This study aimed to investigate the association between the SII combined with the TyG index and mortality risk in CHD patients.

Methods: This study included 970 CHD patients from the MIMIC-IV database. Participants were divided into four quartiles based on median SII and TyG values: T1 (low SII and low TyG), T2 (low SII and high TyG), T3 (high SII and low TyG), and T4 (high SII and high TyG). The combined impact of these indices on CHD patient prognosis was explored using Cox proportional hazards models, Kaplan-Meier survival curves, receiver operating characteristic (ROC) curves, and subgroup analyses.

Results: Compared with the T1 group, the T4 group showed a significantly increased risk of mortality. Multivariate Cox regression analysis revealed the highest 30-day (HR = 2.446, 95% CI 1.366-4.382, p = 0.003) and 1-year (HR = 1.586, 95% CI 1.054-2.387, p = 0.027) mortality risks in the T4 group. ROC curves further confirmed that the combined SII-TyG index demonstrated superior predictive capability for both short-term (AUC = 0.728, 95% CI 0.677-0.778) and long-term (AUC = 0.742, 95% CI 0.703-0.780) outcomes in CHD patients compared to the SII or TyG index alone. Subgroup analyses indicated that the predictive value of the combined index demonstrated considerable universality across different clinical strata. Furthermore, incorporating the combined index into baseline models moderately improved mortality prediction performance. Similarly, a cohort of 1,621 CHD patients from the eICU2.0 database yielded comparable findings: elevated SII and TyG indices correlated with increased in-hospital mortality risk (T4 HR = 3.378, 95% CI 1.716-6.649, p < 0.001), and ROC curve analysis confirmed that combined assessment demonstrated the highest predictive efficacy (AUC = 0.800, 95% CI 0.760-0.840).

Conclusion: In summary, the combined assessment of SII and TyG indices assists clinicians in identifying high-risk populations and improving outcomes for patients with CHD.

背景：全身免疫-炎症指数（SII）和甘油三酯-葡萄糖指数（TyG）对冠心病（CHD）患者短期和长期预后的综合影响尚不清楚。本研究旨在探讨SII联合TyG指数与冠心病患者死亡风险的关系。方法：本研究从MIMIC-IV数据库中纳入970例冠心病患者。参与者根据SII和TyG值的中位数分为四个四分位数：T1（低SII和低TyG）， T2（低SII和高TyG）， T3（高SII和低TyG）和T4（高SII和高TyG）。采用Cox比例风险模型、Kaplan-Meier生存曲线、受试者工作特征（ROC）曲线和亚组分析探讨这些指标对冠心病患者预后的综合影响。结果：与T1组相比，T4组死亡风险明显升高。多因素Cox回归分析显示，T4组30天（HR = 2.446, 95% CI 1.366 ~ 4.382, p = 0.003）和1年（HR = 1.586, 95% CI 1.054 ~ 2.387, p = 0.027）死亡率最高。ROC曲线进一步证实，与单独使用SII或TyG指数相比，联合使用SII-TyG指数对冠心病患者的短期（AUC = 0.728, 95% CI 0.677-0.778）和长期（AUC = 0.742, 95% CI 0.703-0.780）预后的预测能力均优于单独使用SII或TyG指数。亚组分析表明，综合指标的预测价值在不同的临床层次显示出相当大的普遍性。此外，将综合指数纳入基线模型可适度提高死亡率预测性能。同样，来自eICU2.0数据库的1,621例冠心病患者的队列也得出了类似的结果：SII和TyG指数升高与院内死亡风险增加相关（T4 HR = 3.378, 95% CI 1.716-6.649, p）结论：综上所述，SII和TyG指数的联合评估有助于临床医生识别高危人群并改善冠心病患者的预后。
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引用次数: 0
Early-onset hypertension associated with a CACNA1H variant of uncertain significance: a case report and literature review. 早发性高血压与意义不确定的CACNA1H变异相关：1例报告及文献复习
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-04 DOI: 10.1186/s12872-026-05587-1
Xiang Fang, Ruhui Liu, Jing Zeng
{"title":"Early-onset hypertension associated with a CACNA1H variant of uncertain significance: a case report and literature review.","authors":"Xiang Fang, Ruhui Liu, Jing Zeng","doi":"10.1186/s12872-026-05587-1","DOIUrl":"https://doi.org/10.1186/s12872-026-05587-1","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146117856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical relevance of the TAPSE/SPAP ratio in pulmonary arterial hypertension: a single-center retrospective study. 肺动脉高压患者TAPSE/SPAP比值的临床相关性：单中心回顾性研究
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-03 DOI: 10.1186/s12872-026-05567-5
Wenjie Chen, Xiaoqin Luo, Jun Luo, Jie Song, Haihua Qiu, Jingyuan Chen, Chenying Fan, Jiang Li
{"title":"Clinical relevance of the TAPSE/SPAP ratio in pulmonary arterial hypertension: a single-center retrospective study.","authors":"Wenjie Chen, Xiaoqin Luo, Jun Luo, Jie Song, Haihua Qiu, Jingyuan Chen, Chenying Fan, Jiang Li","doi":"10.1186/s12872-026-05567-5","DOIUrl":"https://doi.org/10.1186/s12872-026-05567-5","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The safety and effectiveness of a modified guidewire pigtailing technique in transesophageal echocardiography-guided percutaneous closure of secundum atrial septal defects. 改良导丝拖尾技术在经食管超声心动图引导下经皮房间隔缺损修补术中的安全性和有效性。
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-03 DOI: 10.1186/s12872-026-05576-4
Huipin Hua, Peng Miao, Xun Zhang, Shucan Xu, Jing Jin, Jun Shao
{"title":"The safety and effectiveness of a modified guidewire pigtailing technique in transesophageal echocardiography-guided percutaneous closure of secundum atrial septal defects.","authors":"Huipin Hua, Peng Miao, Xun Zhang, Shucan Xu, Jing Jin, Jun Shao","doi":"10.1186/s12872-026-05576-4","DOIUrl":"https://doi.org/10.1186/s12872-026-05576-4","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous closure of an ultra-long-tunnel-type patent foramen ovale: a rare case with multimodal imaging guidance. 经皮缝合超长隧道型卵圆孔未闭：一例罕见的多模式影像引导。
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-03 DOI: 10.1186/s12872-026-05529-x
Bo Li, Ming Li, Beibei Song

Patent foramen ovale (PFO) is a common congenital cardiac anomaly, and ultra-long tunnel PFO (> 20 mm) presents a significant interventional challenge despite routine standard closure. A 68-year-old female with recurrent headaches, chest pain history, and prior right coronary artery stenting was confirmed to have a 37-mm ultra-long tunnel PFO via transesophageal echocardiography (TEE) and digital subtraction angiography (DSA). After initial percutaneous closure failure, the patient was successfully treated with a modified trans-tunnel puncture technique and deployment of an Abbott 18/25 mm Amplatzer PFO Occluder. Follow-up showed gradual resolution of residual shunt, with no shunt detected by June 2025. The imaging-guided modified trans-tunnel puncture technique is an effective strategy for complex ultra-long tunnel PFOs.

卵圆孔未闭（PFO）是一种常见的先天性心脏异常，尽管常规标准闭合，超长隧道PFO （bbb20 mm）仍然存在重大的介入挑战。68岁女性，反复头痛，胸痛病史，既往右冠状动脉支架植入术，经食管超声心动图（TEE）和数字减影血管造影（DSA）证实为37毫米超长隧道PFO。在最初的经皮闭合失败后，患者通过改进的跨隧道穿刺技术和部署Abbott 18/25 mm Amplatzer PFO闭塞器成功治疗。随访显示残余分流逐渐消失，到2025年6月未发现分流。成像引导下的改进跨隧道穿刺技术是治疗复杂超长隧道PFOs的有效策略。
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引用次数: 0
Association between autoimmune diseases and atrial fibrillation: a real-world analysis from German outpatient data. 自身免疫性疾病与心房颤动之间的关联：来自德国门诊数据的真实世界分析
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-02 DOI: 10.1186/s12872-026-05559-5
Jamschid Sedighi, Mark Luedde, Priyanka Boettger, Boris Dinov, Birgit Assmus, Samuel Sossalla, Karel Kostev
{"title":"Association between autoimmune diseases and atrial fibrillation: a real-world analysis from German outpatient data.","authors":"Jamschid Sedighi, Mark Luedde, Priyanka Boettger, Boris Dinov, Birgit Assmus, Samuel Sossalla, Karel Kostev","doi":"10.1186/s12872-026-05559-5","DOIUrl":"https://doi.org/10.1186/s12872-026-05559-5","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146104123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety profile of ticagrelor: an analysis based on literature and database review. 替格瑞洛的安全性：基于文献和数据库回顾的分析。
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-02 DOI: 10.1186/s12872-026-05536-y
Renzhu Liu, Lu Xiao, Qingzi Yan, Xiang Liu
{"title":"Safety profile of ticagrelor: an analysis based on literature and database review.","authors":"Renzhu Liu, Lu Xiao, Qingzi Yan, Xiang Liu","doi":"10.1186/s12872-026-05536-y","DOIUrl":"https://doi.org/10.1186/s12872-026-05536-y","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146104066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of levels of cardiac troponins between asphyxiated and normal neonates in Enugu. 埃努古地区窒息和正常新生儿心肌肌钙蛋白水平的测定。
IF 2.3 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
BMC Cardiovascular Disorders
Pub Date : 2026-02-02 DOI: 10.1186/s12872-026-05556-8
Philip C Elobuike, Herbert A Obu, Ann E Aronu, Josephat M Chinawa
{"title":"Determination of levels of cardiac troponins between asphyxiated and normal neonates in Enugu.","authors":"Philip C Elobuike, Herbert A Obu, Ann E Aronu, Josephat M Chinawa","doi":"10.1186/s12872-026-05556-8","DOIUrl":"https://doi.org/10.1186/s12872-026-05556-8","url":null,"abstract":"","PeriodicalId":9195,"journal":{"name":"BMC Cardiovascular Disorders","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146104117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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