{"title":"Psychological impact of infertility on women in Kathmandu, Nepal: a cross-sectional study of depressive symptoms and associated factors.","authors":"Pratima Dawadi, Sabina Shrestha, Prabha Dawadee, Rajendra Gautam","doi":"10.1186/s12905-026-04349-7","DOIUrl":"https://doi.org/10.1186/s12905-026-04349-7","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146218870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-19DOI: 10.1186/s12905-026-04352-y
Jiatian Ye, Xinyi Qiu Mm, Xiaorong Qi
{"title":"Fertility-preserving treatment for endometrial atypical hyperplasia and endometrial cancer: a systematic review and meta-analysis.","authors":"Jiatian Ye, Xinyi Qiu Mm, Xiaorong Qi","doi":"10.1186/s12905-026-04352-y","DOIUrl":"https://doi.org/10.1186/s12905-026-04352-y","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146225583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-17DOI: 10.1186/s12905-026-04342-0
Jia Pu, Lan Huang, Yuemei Li, Qianmei Zhong
{"title":"Latent profile analysis of reproductive concern among women of childbearing age with systemic lupus erythematosus in China: a cross-sectional study.","authors":"Jia Pu, Lan Huang, Yuemei Li, Qianmei Zhong","doi":"10.1186/s12905-026-04342-0","DOIUrl":"https://doi.org/10.1186/s12905-026-04342-0","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146212160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-17DOI: 10.1186/s12905-026-04348-8
Anna Biasioli, Francesca Previtera, Ilaria Mazzera, Matilde Degano, Silvia Zermano, Veronica Tius, Ilaria Piacenti, Renato Seracchioli, Diego Raimondo, Monica Della Martina, Martina Arcieri, Stefano Restaino, Lorenza Driul, Giuseppe Vizzielli
Background: Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form of nociplastic pain, is associated with various chronic pain syndromes collectively known as Central Sensitivity Syndromes, such as fibromyalgia and irritable bowel syndrome. These central mechanisms may contribute to treatment failure and symptom recurrence in endometriosis, significantly impacting quality of life. The Central Sensitization Inventory (CSI), initially validated in patients with fibromyalgia, has demonstrated utility in identifying central sensitization in those with endometriosis. The primary outcome of this study was to assess the prevalence of central sensitization in patients with a diagnosis of endometriosis/adenomyosis. The secondary objective was to evaluate the association between the patient's demographic and clinical characteristics and the diagnosis of central sensitization syndrome.
Methods: This was a single-center, observational, cross-sectional study. Between February 1, 2023, and August 31, 2023, we prospectively enrolled 142 patients with a diagnosis of endometriosis/adenomyosis, as determined by surgery/ultrasound, who attended the "Endometriosis and Pelvic Pain" unit within the Obstetrics and Gynecology Clinic in Udine. Demographic and clinical data were collected. The prevalence of central sensitization was assessed using a validated questionnaire, the Central Sensitization Inventory. A CSI score ≥ 40 was considered as an indicator of Central Sensitization Syndrome.
Results: The prevalence of CS was 52.1%. Among the clinical characteristics, only dyspareunia and vulvodynia were significantly associated with CS in our patients (p < 0.001), while other symptoms and even the type of endometriosis were not. However, a significant association was found with the onset of symptoms being more than 5 years, compared to earlier-onset forms (p < 0.001). A strong association was also found between positive CSI and overlap syndromes.
Conclusions: Given the high prevalence of central sensitization based on the CSI among this tertiary-referral cohort, identifying it precociously might be useful for counseling patients and choosing a multimodal treatment in addition to conventional strategies. Further studies are needed to confirm these findings in broader and non-selected populations and to validate the applicability of the CSI questionnaire as a screening tool for central sensitization in common practice.
{"title":"Central sensitization in women with endometriosis: a cross-sectional study.","authors":"Anna Biasioli, Francesca Previtera, Ilaria Mazzera, Matilde Degano, Silvia Zermano, Veronica Tius, Ilaria Piacenti, Renato Seracchioli, Diego Raimondo, Monica Della Martina, Martina Arcieri, Stefano Restaino, Lorenza Driul, Giuseppe Vizzielli","doi":"10.1186/s12905-026-04348-8","DOIUrl":"https://doi.org/10.1186/s12905-026-04348-8","url":null,"abstract":"<p><strong>Background: </strong>Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form of nociplastic pain, is associated with various chronic pain syndromes collectively known as Central Sensitivity Syndromes, such as fibromyalgia and irritable bowel syndrome. These central mechanisms may contribute to treatment failure and symptom recurrence in endometriosis, significantly impacting quality of life. The Central Sensitization Inventory (CSI), initially validated in patients with fibromyalgia, has demonstrated utility in identifying central sensitization in those with endometriosis. The primary outcome of this study was to assess the prevalence of central sensitization in patients with a diagnosis of endometriosis/adenomyosis. The secondary objective was to evaluate the association between the patient's demographic and clinical characteristics and the diagnosis of central sensitization syndrome.</p><p><strong>Methods: </strong>This was a single-center, observational, cross-sectional study. Between February 1, 2023, and August 31, 2023, we prospectively enrolled 142 patients with a diagnosis of endometriosis/adenomyosis, as determined by surgery/ultrasound, who attended the \"Endometriosis and Pelvic Pain\" unit within the Obstetrics and Gynecology Clinic in Udine. Demographic and clinical data were collected. The prevalence of central sensitization was assessed using a validated questionnaire, the Central Sensitization Inventory. A CSI score ≥ 40 was considered as an indicator of Central Sensitization Syndrome.</p><p><strong>Results: </strong>The prevalence of CS was 52.1%. Among the clinical characteristics, only dyspareunia and vulvodynia were significantly associated with CS in our patients (p < 0.001), while other symptoms and even the type of endometriosis were not. However, a significant association was found with the onset of symptoms being more than 5 years, compared to earlier-onset forms (p < 0.001). A strong association was also found between positive CSI and overlap syndromes.</p><p><strong>Conclusions: </strong>Given the high prevalence of central sensitization based on the CSI among this tertiary-referral cohort, identifying it precociously might be useful for counseling patients and choosing a multimodal treatment in addition to conventional strategies. Further studies are needed to confirm these findings in broader and non-selected populations and to validate the applicability of the CSI questionnaire as a screening tool for central sensitization in common practice.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146212225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-16DOI: 10.1186/s12905-026-04336-y
Hui Feng, Jian Zhao, Jing Zhang, Peng Jia, Yan Zhang
{"title":"The role of E7 oncoprotein self-sampling and self-testing in cervical cancer screening.","authors":"Hui Feng, Jian Zhao, Jing Zhang, Peng Jia, Yan Zhang","doi":"10.1186/s12905-026-04336-y","DOIUrl":"https://doi.org/10.1186/s12905-026-04336-y","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146200262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-13DOI: 10.1186/s12905-026-04300-w
Ashraful Alam, Md Emon Prodhan, Tahmina Akhter, Naymul Islam Sagar, Mohammad Nayeem Hasan
<p><strong>Background: </strong>Women in low- and middle-income nations are disproportionately afflicted by depression and anxiety, which are contributing factors to the worldwide disease burden. The purpose of this study is to measure the prevalence of anxiety and depression in Bangladeshi women aged 15-49 years and to evaluate the associations between these mental health outcomes and three aspects of empowerment (attitudes toward violence, social independence, and decision-making autonomy).</p><p><strong>Methods: </strong>This study analyzed cross-sectional data from the 2022 Bangladesh Demographic and Health Survey. Empowerment was measured with the survey-based women's empowerment (SWPER) index and categorized as low, medium or high for each domain. Bivariate analysis via chi-square tests was used to identify significant covariates associated with the outcomes. Survey-weighted logistic regressions were performed to estimate adjusted odds ratios (AORs) with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>High anxiety and depression affected 8.1% and 10.4% of the women, respectively. Low empowerment in the attitudes toward violence was associated with high anxiety (AOR = 1.42, 95% CI: 1.07-1.89) and depression (AOR = 1.54, 95% CI: 1.19-1.99). Social independence empowerment was significantly associated with anxiety (low: AOR = 1.38, 95% CI: 1.12-1.69; medium: AOR = 1.24, 95% CI: 1.02-1.51), whereas in the decision-making section, medium and high empowerment increased anxiety risk (medium: AOR = 1.47, 95% CI: 1.17-1.86; high: AOR = 1.44, 95% CI: 1.15-1.82). Compared with women aged 15-24 years, those aged 25-34 years had increased risks of both anxiety (AOR = 1.69, 95% CI: 1.37-2.07) and depression (AOR = 1.43, 95% CI: 1.19-1.74), as did women aged 35-49 years (anxiety: AOR = 1.96, 95% CI: 1.56-2.47; depression: AOR = 1.55, 95% CI: 1.27-1.89). Agricultural work was protective against anxiety (AOR = 0.75, 95% CI: 0.64-0.88), whereas skilled/professional employment increased anxiety (AOR = 1.23, 95% CI: 1.01-1.49). Husband unemployment amplified both outcomes (anxiety: AOR = 1.88, 95% CI: 1.45-2.43; depression: AOR = 1.59, 95% CI: 1.25-2.02). Poverty heightened anxiety (AOR = 1.21, 95% CI: 1.03-1.42), whereas a lack of internet use elevated depression (AOR = 1.28, 95% CI: 1.09-1.52). Muslim women had increased risks of anxiety (AOR = 1.63, 95% CI: 1.24-2.13) and depression (AOR = 1.43, 95% CI: 1.12-1.83). Divisional disparities were also a significant risk factor for both anxiety (Rangpur: AOR = 1.66, 95% CI: 1.19-2.31; Khulna: AOR = 1.40, 95% CI: 1.02-1.93) and depression (Rangpur: AOR = 1.86, 95% CI: 1.43-2.40; Khulna: AOR = 1.34, 95% CI: 1.02-1.76). Conversely, having one to two children was protective against depression (AOR = 0.75, 95% CI: 0.61-0.92).</p><p><strong>Conclusions: </strong>Women's empowerment affects mental health in opposite ways: rejecting violence and gaining social independence lowers anxiety and depression,
{"title":"SWPER-Measured women's empowerment and mental health in Bangladesh: a cross-sectional study from 2022 demographic and health survey.","authors":"Ashraful Alam, Md Emon Prodhan, Tahmina Akhter, Naymul Islam Sagar, Mohammad Nayeem Hasan","doi":"10.1186/s12905-026-04300-w","DOIUrl":"10.1186/s12905-026-04300-w","url":null,"abstract":"<p><strong>Background: </strong>Women in low- and middle-income nations are disproportionately afflicted by depression and anxiety, which are contributing factors to the worldwide disease burden. The purpose of this study is to measure the prevalence of anxiety and depression in Bangladeshi women aged 15-49 years and to evaluate the associations between these mental health outcomes and three aspects of empowerment (attitudes toward violence, social independence, and decision-making autonomy).</p><p><strong>Methods: </strong>This study analyzed cross-sectional data from the 2022 Bangladesh Demographic and Health Survey. Empowerment was measured with the survey-based women's empowerment (SWPER) index and categorized as low, medium or high for each domain. Bivariate analysis via chi-square tests was used to identify significant covariates associated with the outcomes. Survey-weighted logistic regressions were performed to estimate adjusted odds ratios (AORs) with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>High anxiety and depression affected 8.1% and 10.4% of the women, respectively. Low empowerment in the attitudes toward violence was associated with high anxiety (AOR = 1.42, 95% CI: 1.07-1.89) and depression (AOR = 1.54, 95% CI: 1.19-1.99). Social independence empowerment was significantly associated with anxiety (low: AOR = 1.38, 95% CI: 1.12-1.69; medium: AOR = 1.24, 95% CI: 1.02-1.51), whereas in the decision-making section, medium and high empowerment increased anxiety risk (medium: AOR = 1.47, 95% CI: 1.17-1.86; high: AOR = 1.44, 95% CI: 1.15-1.82). Compared with women aged 15-24 years, those aged 25-34 years had increased risks of both anxiety (AOR = 1.69, 95% CI: 1.37-2.07) and depression (AOR = 1.43, 95% CI: 1.19-1.74), as did women aged 35-49 years (anxiety: AOR = 1.96, 95% CI: 1.56-2.47; depression: AOR = 1.55, 95% CI: 1.27-1.89). Agricultural work was protective against anxiety (AOR = 0.75, 95% CI: 0.64-0.88), whereas skilled/professional employment increased anxiety (AOR = 1.23, 95% CI: 1.01-1.49). Husband unemployment amplified both outcomes (anxiety: AOR = 1.88, 95% CI: 1.45-2.43; depression: AOR = 1.59, 95% CI: 1.25-2.02). Poverty heightened anxiety (AOR = 1.21, 95% CI: 1.03-1.42), whereas a lack of internet use elevated depression (AOR = 1.28, 95% CI: 1.09-1.52). Muslim women had increased risks of anxiety (AOR = 1.63, 95% CI: 1.24-2.13) and depression (AOR = 1.43, 95% CI: 1.12-1.83). Divisional disparities were also a significant risk factor for both anxiety (Rangpur: AOR = 1.66, 95% CI: 1.19-2.31; Khulna: AOR = 1.40, 95% CI: 1.02-1.93) and depression (Rangpur: AOR = 1.86, 95% CI: 1.43-2.40; Khulna: AOR = 1.34, 95% CI: 1.02-1.76). Conversely, having one to two children was protective against depression (AOR = 0.75, 95% CI: 0.61-0.92).</p><p><strong>Conclusions: </strong>Women's empowerment affects mental health in opposite ways: rejecting violence and gaining social independence lowers anxiety and depression, ","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":"119"},"PeriodicalIF":2.7,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12918478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-13DOI: 10.1186/s12905-026-04306-4
Valeria Schellenberg, Till Neugebauer, Yüce Yilmaz-Aslan, Patrick Brzoska
{"title":"Trends in endometriosis hospitalizations in Germany, 2000-2023.","authors":"Valeria Schellenberg, Till Neugebauer, Yüce Yilmaz-Aslan, Patrick Brzoska","doi":"10.1186/s12905-026-04306-4","DOIUrl":"10.1186/s12905-026-04306-4","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12930568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-13DOI: 10.1186/s12905-026-04335-z
Anna Cirkel, Hartmut Göbel, Carl Göbel, Ibrahim Alkatout, Antonia Kaiser, Norbert Brüggemann, Jens Minnerup, Achim Rody, Christoph Cirkel
{"title":"Prevalence of migraine subtypes in women with endometriosis and/or dysmenorrhea: results from a cross-sectional multicenter trial.","authors":"Anna Cirkel, Hartmut Göbel, Carl Göbel, Ibrahim Alkatout, Antonia Kaiser, Norbert Brüggemann, Jens Minnerup, Achim Rody, Christoph Cirkel","doi":"10.1186/s12905-026-04335-z","DOIUrl":"10.1186/s12905-026-04335-z","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12930695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146177729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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