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Microglia-neuronal communication mediated by P2X4R–BDNF-TrkB promotes synaptic plasticity and anterior cingulate cortex hyperactivity in muscle pain chronicity. Comment on Br J Anaesth 2025; 135: 710–22 P2X4R-BDNF-TrkB介导的小胶质细胞-神经元通讯促进了肌肉疼痛慢性中的突触可塑性和前扣带皮质亢进。Br [J][研究][2025];135: 710 - 22所示
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-03-01 Epub Date: 2026-01-13 DOI: 10.1016/j.bja.2025.12.018
Parth Aphale, Himanshu Shekhar, Shashank Dokania
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引用次数: 0
Laryngeal mask airway sizes: evaluation of the use of the size 6 LMA 喉罩气道尺寸:评估6尺寸LMA的使用。
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-03-01 Epub Date: 2026-01-16 DOI: 10.1016/j.bja.2025.12.024
Katherine McKee , James Turnbull , Anil Patel , Archie I.J. Brain
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引用次数: 0
Associate Editorial Board and cover image caption 副编辑委员会和封面图片说明
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-03-01 Epub Date: 2026-02-21 DOI: 10.1016/S0007-0912(26)00068-1
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引用次数: 0
Impact of peripheral nerve blocks on chronic opioid use after elective total knee arthroplasty from a large US claims database: impact of intraoperative opioids. Comment on Br J Anaesth 2025; 134: 1779-83. 来自美国大型索赔数据库的外周神经阻滞对选择性全膝关节置换术后慢性阿片类药物使用的影响:术中阿片类药物的影响Br [J][研究][2025];134: 1779 - 83。
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-28 DOI: 10.1016/j.bja.2026.01.045
Brian A Williams, Michael S Patzkowski
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引用次数: 0
Impact of propofol or sevoflurane on the renoprotective effect of remote ischaemic preconditioning in cardiac surgery. Response to Br J Anaesth 2026; 136:1098-9. 异丙酚或七氟醚对心脏手术中远程缺血预处理肾保护作用的影响。生物工程学报,2016;136:1098-9。
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-28 DOI: 10.1016/j.bja.2026.01.038
Alexander Zarbock, John A Kellum
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引用次数: 0
Managing postinduction hypotension: the jury is still out. 诱导后低血压的处理:尚无定论。
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-27 DOI: 10.1016/j.bja.2026.01.035
Kristen K Thomsen, Matthieu Legrand

The EPITUBE trial compared preventive continuous norepinephrine infusion with reactive ephedrine bolus injections in patients undergoing cardiac surgery during induction of anaesthesia, showing no difference in the incidence of severe postinduction hypotension or postoperative outcomes. However, several design features limited the ability to detect a treatment effect, including rescue ephedrine use in the norepinephrine group, absence of vasopressor use in more than half of control patients, and widespread norepinephrine exposure later in surgery. As a result, the two groups achieved only minimal separation in actual vasopressor exposure. The findings reinforce that preventive norepinephrine infusion is feasible and safe, but further research is needed to determine whether it can improve outcomes in selected surgical populations.

EPITUBE试验比较了心脏手术患者在麻醉诱导期间预防性持续输注去甲肾上腺素和反应性麻黄素丸注射,在诱导后严重低血压的发生率和术后结局方面没有差异。然而,一些设计特征限制了检测治疗效果的能力,包括在去甲肾上腺素组中使用救援麻黄素,超过一半的对照患者不使用血管加压素,以及手术后期广泛使用去甲肾上腺素。结果,两组在实际的血管加压素暴露中只实现了最小的分离。研究结果强调预防性去甲肾上腺素输注是可行和安全的,但需要进一步的研究来确定它是否能改善选定手术人群的预后。
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引用次数: 0
Corrigendum to 'Functional analysis of RYR1 variants in Australian and New Zealand patients at risk of susceptibility to malignant hyperthermia' (Br J Anaesth 2026; 136: 323-32). “澳大利亚和新西兰恶性高热易感性患者RYR1变异的功能分析”的勘误表(Br J Anaesth 2026; 136: 323-32)。
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-27 DOI: 10.1016/j.bja.2026.02.003
Anja H Schiemann, Sophie M Burling, Remai Allen, Terasa Bulger, Roslyn G Machon, Margaret Perry, Neil Street, Luuk R van den Bersselaar, Kathryn M Stowell
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引用次数: 0
Continuous versus bolus norepinephrine administration and arterial blood pressure stability during induction of general anaesthesia in high-risk noncardiac surgery patients. Response to Br J Anaesth 2026; 136: 425-6. 高危非心脏手术患者全麻诱导期间持续与大剂量去甲肾上腺素与动脉血压稳定性的比较生物工程学报,2016;136: 425 - 6。
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-27 DOI: 10.1016/j.bja.2026.01.043
Christina Vokuhl, Kristen K Thomsen
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引用次数: 0
qNOX index for quantification of intraoperative nociception and analgesia: limitations to clinical utility. Response to Br J Anaesth 2026; 136: 1057-8. qNOX指数用于术中疼痛和镇痛的量化:临床应用的局限性。生物工程学报,2016;136: 1057 - 8。
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-27 DOI: 10.1016/j.bja.2026.01.039
Hao Kong, Hong Zhang
{"title":"qNOX index for quantification of intraoperative nociception and analgesia: limitations to clinical utility. Response to Br J Anaesth 2026; 136: 1057-8.","authors":"Hao Kong, Hong Zhang","doi":"10.1016/j.bja.2026.01.039","DOIUrl":"https://doi.org/10.1016/j.bja.2026.01.039","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147321345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The aetiology of recurrent perioperative hypersensitivity reactions in a large French cohort. 法国一个大型队列中复发性围手术期超敏反应的病因分析。
IF 9.2 1区 医学 Q1 ANESTHESIOLOGY Pub Date : 2026-02-27 DOI: 10.1016/j.bja.2026.01.040
Khalif Bouaita, Catherine Neukirch, Simon Aubert, Pascale Roland-Nicaise, Philippe Montravers, Luc de Chaisemartin, Aurélie Gouel-Chéron
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引用次数: 0
期刊
British journal of anaesthesia
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